http://togogenome.org/gene/1178016:EROM_100280 ^@ http://purl.uniprot.org/uniprot/I7AGF4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/1178016:EROM_081530 ^@ http://purl.uniprot.org/uniprot/I7AP38 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/1178016:EROM_101240 ^@ http://purl.uniprot.org/uniprot/I7APY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_051470 ^@ http://purl.uniprot.org/uniprot/I7ARS2 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/1178016:EROM_060390 ^@ http://purl.uniprot.org/uniprot/I6ZIW7 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/1178016:EROM_101540 ^@ http://purl.uniprot.org/uniprot/I7AQ15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_041010 ^@ http://purl.uniprot.org/uniprot/I6ZI25 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_040830 ^@ http://purl.uniprot.org/uniprot/I6ZT92 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/1178016:EROM_071550 ^@ http://purl.uniprot.org/uniprot/I6ZUM2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DCP2 subfamily. http://togogenome.org/gene/1178016:EROM_010390 ^@ http://purl.uniprot.org/uniprot/I7AL57 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_061270 ^@ http://purl.uniprot.org/uniprot/I6ZJ28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_041210 ^@ http://purl.uniprot.org/uniprot/I7AR97 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/1178016:EROM_020680 ^@ http://purl.uniprot.org/uniprot/I6ZH70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.|||Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.|||Endoplasmic reticulum membrane http://togogenome.org/gene/1178016:EROM_080260 ^@ http://purl.uniprot.org/uniprot/I6ZJM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/1178016:EROM_070910 ^@ http://purl.uniprot.org/uniprot/I7ASD6 ^@ Similarity ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_081080 ^@ http://purl.uniprot.org/uniprot/I7ANZ9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/1178016:EROM_111430 ^@ http://purl.uniprot.org/uniprot/I7AQJ0 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/1178016:EROM_060590 ^@ http://purl.uniprot.org/uniprot/I6ZIY5 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/1178016:EROM_080550 ^@ http://purl.uniprot.org/uniprot/I7AFH9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/1178016:EROM_100260 ^@ http://purl.uniprot.org/uniprot/I6ZKL5 ^@ Similarity ^@ In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family. http://togogenome.org/gene/1178016:EROM_041090 ^@ http://purl.uniprot.org/uniprot/I6ZTB2 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/1178016:EROM_081920 ^@ http://purl.uniprot.org/uniprot/I6ZV32 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/1178016:EROM_061500 ^@ http://purl.uniprot.org/uniprot/I6ZUA4 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/1178016:EROM_110850 ^@ http://purl.uniprot.org/uniprot/I7AUA8 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/1178016:EROM_020200 ^@ http://purl.uniprot.org/uniprot/I7AD17 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/1178016:EROM_110050 ^@ http://purl.uniprot.org/uniprot/I7AQ36 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_111760 ^@ http://purl.uniprot.org/uniprot/I7AUL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/1178016:EROM_101610 ^@ http://purl.uniprot.org/uniprot/I6ZW39 ^@ Similarity ^@ Belongs to the HIT family. http://togogenome.org/gene/1178016:EROM_021390 ^@ http://purl.uniprot.org/uniprot/I7ALR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC24 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/1178016:EROM_010090 ^@ http://purl.uniprot.org/uniprot/I7AL28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/1178016:EROM_041400 ^@ http://purl.uniprot.org/uniprot/I6ZTD2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_071620 ^@ http://purl.uniprot.org/uniprot/I6ZJJ3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/1178016:EROM_031110 ^@ http://purl.uniprot.org/uniprot/I6ZHR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.|||Cytoplasm|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. http://togogenome.org/gene/1178016:EROM_110920 ^@ http://purl.uniprot.org/uniprot/I7AQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1178016:EROM_100880 ^@ http://purl.uniprot.org/uniprot/I7APU8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_060410 ^@ http://purl.uniprot.org/uniprot/I7AER8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/1178016:EROM_060110 ^@ http://purl.uniprot.org/uniprot/I6ZTV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_100400 ^@ http://purl.uniprot.org/uniprot/I6ZVT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/1178016:EROM_070690 ^@ http://purl.uniprot.org/uniprot/I7AF61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane|||Water channel required to facilitate the transport of water across membranes. Involved in osmotolerance. http://togogenome.org/gene/1178016:EROM_061430 ^@ http://purl.uniprot.org/uniprot/I7ANA8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/1178016:EROM_010250 ^@ http://purl.uniprot.org/uniprot/I7ACR0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_020840 ^@ http://purl.uniprot.org/uniprot/I7ALK9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_071680 ^@ http://purl.uniprot.org/uniprot/I7ANQ8 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/1178016:EROM_111400 ^@ http://purl.uniprot.org/uniprot/I6ZWG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_101490 ^@ http://purl.uniprot.org/uniprot/I7AQ10 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/1178016:EROM_060080 ^@ http://purl.uniprot.org/uniprot/I6ZIQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Membrane http://togogenome.org/gene/1178016:EROM_041370 ^@ http://purl.uniprot.org/uniprot/I6ZI53 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1178016:EROM_101660 ^@ http://purl.uniprot.org/uniprot/I6ZW44 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1178016:EROM_070600 ^@ http://purl.uniprot.org/uniprot/I6ZUF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_050260 ^@ http://purl.uniprot.org/uniprot/I7AML5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus http://togogenome.org/gene/1178016:EROM_110480 ^@ http://purl.uniprot.org/uniprot/I7AGV4 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1178016:EROM_071010 ^@ http://purl.uniprot.org/uniprot/I7ASE4 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/1178016:EROM_100330 ^@ http://purl.uniprot.org/uniprot/I7AGF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1178016:EROM_101190 ^@ http://purl.uniprot.org/uniprot/I7APY0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/1178016:EROM_011170 ^@ http://purl.uniprot.org/uniprot/I6ZS80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_050870 ^@ http://purl.uniprot.org/uniprot/I7AMQ6 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1178016:EROM_020360 ^@ http://purl.uniprot.org/uniprot/I6ZSC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. http://togogenome.org/gene/1178016:EROM_030700 ^@ http://purl.uniprot.org/uniprot/I6ZSX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/1178016:EROM_081430 ^@ http://purl.uniprot.org/uniprot/I7AP29 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/1178016:EROM_061510 ^@ http://purl.uniprot.org/uniprot/I7AS60 ^@ Similarity ^@ Belongs to the DNA polymerase type-B-like family. http://togogenome.org/gene/1178016:EROM_070440 ^@ http://purl.uniprot.org/uniprot/I7AF42 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/1178016:EROM_111510 ^@ http://purl.uniprot.org/uniprot/I7AUJ9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/1178016:EROM_040570 ^@ http://purl.uniprot.org/uniprot/I7ADZ2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/1178016:EROM_110780 ^@ http://purl.uniprot.org/uniprot/I7AGY1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1178016:EROM_101370 ^@ http://purl.uniprot.org/uniprot/I7ATZ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_110800 ^@ http://purl.uniprot.org/uniprot/I7AUA3 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/1178016:EROM_040890 ^@ http://purl.uniprot.org/uniprot/I6ZT96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC1 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_071250 ^@ http://purl.uniprot.org/uniprot/I6ZUK2 ^@ Similarity ^@ Belongs to the FAM72 family. http://togogenome.org/gene/1178016:EROM_060420 ^@ http://purl.uniprot.org/uniprot/I6ZU21 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/1178016:EROM_100840 ^@ http://purl.uniprot.org/uniprot/I7AGK2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/1178016:EROM_080770 ^@ http://purl.uniprot.org/uniprot/I6ZUU4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_070840 ^@ http://purl.uniprot.org/uniprot/I7AF73 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||This promotes the activity of RNA polymerase II. http://togogenome.org/gene/1178016:EROM_021120 ^@ http://purl.uniprot.org/uniprot/I7AQJ2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily. http://togogenome.org/gene/1178016:EROM_051020 ^@ http://purl.uniprot.org/uniprot/I6ZII5 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1178016:EROM_071210 ^@ http://purl.uniprot.org/uniprot/I7ASG3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_071390 ^@ http://purl.uniprot.org/uniprot/I7AFB6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family. http://togogenome.org/gene/1178016:EROM_080480 ^@ http://purl.uniprot.org/uniprot/I7AFH5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_051000 ^@ http://purl.uniprot.org/uniprot/I6ZTN6 ^@ Similarity ^@ Belongs to the NARF family. http://togogenome.org/gene/1178016:EROM_030810 ^@ http://purl.uniprot.org/uniprot/I7AQW5 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/1178016:EROM_081940 ^@ http://purl.uniprot.org/uniprot/I6ZK19 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_061540 ^@ http://purl.uniprot.org/uniprot/I7AF02 ^@ Similarity ^@ Belongs to the WD repeat rae1 family. http://togogenome.org/gene/1178016:EROM_081510 ^@ http://purl.uniprot.org/uniprot/I7ASY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/1178016:EROM_110980 ^@ http://purl.uniprot.org/uniprot/I7AGZ8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_050770 ^@ http://purl.uniprot.org/uniprot/I7AMP8 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/1178016:EROM_110900 ^@ http://purl.uniprot.org/uniprot/I7AUB4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_020700 ^@ http://purl.uniprot.org/uniprot/I7AD68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus http://togogenome.org/gene/1178016:EROM_080830 ^@ http://purl.uniprot.org/uniprot/I6ZUU6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/1178016:EROM_060440 ^@ http://purl.uniprot.org/uniprot/I6ZIX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_040790 ^@ http://purl.uniprot.org/uniprot/I7AR67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/1178016:EROM_031070 ^@ http://purl.uniprot.org/uniprot/I7AM30 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/1178016:EROM_080850 ^@ http://purl.uniprot.org/uniprot/I6ZJS5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/1178016:EROM_101460 ^@ http://purl.uniprot.org/uniprot/I6ZW25 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/1178016:EROM_050230 ^@ http://purl.uniprot.org/uniprot/I6ZTG9 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1178016:EROM_110680 ^@ http://purl.uniprot.org/uniprot/I7AGX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/1178016:EROM_060680 ^@ http://purl.uniprot.org/uniprot/I6ZU41 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1178016:EROM_081770 ^@ http://purl.uniprot.org/uniprot/I6ZK05 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_050290 ^@ http://purl.uniprot.org/uniprot/I7ARG3 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/1178016:EROM_011100 ^@ http://purl.uniprot.org/uniprot/I7ALB8 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1178016:EROM_030490 ^@ http://purl.uniprot.org/uniprot/I7ADM7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_111030 ^@ http://purl.uniprot.org/uniprot/I7AH04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_100110 ^@ http://purl.uniprot.org/uniprot/I7APN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Cytoplasm|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_051150 ^@ http://purl.uniprot.org/uniprot/I6ZTQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_071670 ^@ http://purl.uniprot.org/uniprot/I6ZJJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/1178016:EROM_110320 ^@ http://purl.uniprot.org/uniprot/I7AQ59 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_060020 ^@ http://purl.uniprot.org/uniprot/I7ART9 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/1178016:EROM_081450 ^@ http://purl.uniprot.org/uniprot/I6ZUY5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. http://togogenome.org/gene/1178016:EROM_110300 ^@ http://purl.uniprot.org/uniprot/I7AU54 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/1178016:EROM_021320 ^@ http://purl.uniprot.org/uniprot/I7AQK9 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/1178016:EROM_021270 ^@ http://purl.uniprot.org/uniprot/I7AQK5 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_080270 ^@ http://purl.uniprot.org/uniprot/I7ANT3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/1178016:EROM_111060 ^@ http://purl.uniprot.org/uniprot/I6ZL85 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/1178016:EROM_021260 ^@ http://purl.uniprot.org/uniprot/I6ZSL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/1178016:EROM_070030 ^@ http://purl.uniprot.org/uniprot/I7ANC1 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1178016:EROM_051050 ^@ http://purl.uniprot.org/uniprot/I6ZTP0 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/1178016:EROM_080510 ^@ http://purl.uniprot.org/uniprot/I7ASQ3 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/1178016:EROM_010800 ^@ http://purl.uniprot.org/uniprot/I7AL93 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1178016:EROM_050240 ^@ http://purl.uniprot.org/uniprot/I7ARF7 ^@ Similarity ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_100040 ^@ http://purl.uniprot.org/uniprot/I6ZKJ9 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/1178016:EROM_080320 ^@ http://purl.uniprot.org/uniprot/I7ANT8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1178016:EROM_071290 ^@ http://purl.uniprot.org/uniprot/I7AFA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''. http://togogenome.org/gene/1178016:EROM_070960 ^@ http://purl.uniprot.org/uniprot/I7ASE0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/1178016:EROM_110060 ^@ http://purl.uniprot.org/uniprot/I7AGS6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_070330 ^@ http://purl.uniprot.org/uniprot/I7ANE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC6 subfamily.|||Chromosome|||Nucleus http://togogenome.org/gene/1178016:EROM_100590 ^@ http://purl.uniprot.org/uniprot/I7AGH9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/1178016:EROM_100430 ^@ http://purl.uniprot.org/uniprot/I7APQ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1178016:EROM_100320 ^@ http://purl.uniprot.org/uniprot/I7APP7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1178016:EROM_080630 ^@ http://purl.uniprot.org/uniprot/I7ASR0 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. http://togogenome.org/gene/1178016:EROM_030940 ^@ http://purl.uniprot.org/uniprot/I7ADR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_081100 ^@ http://purl.uniprot.org/uniprot/I6ZUW1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. http://togogenome.org/gene/1178016:EROM_020500 ^@ http://purl.uniprot.org/uniprot/I7AD46 ^@ Function|||Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1178016:EROM_060720 ^@ http://purl.uniprot.org/uniprot/I7AEU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_070490 ^@ http://purl.uniprot.org/uniprot/I7AF45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/1178016:EROM_060430 ^@ http://purl.uniprot.org/uniprot/I7AS00 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_080150 ^@ http://purl.uniprot.org/uniprot/I7ASM2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_050360 ^@ http://purl.uniprot.org/uniprot/I7AMM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_060940 ^@ http://purl.uniprot.org/uniprot/I6ZU60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Cytoplasm|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_080870 ^@ http://purl.uniprot.org/uniprot/I7AFJ9 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/1178016:EROM_070560 ^@ http://purl.uniprot.org/uniprot/I7ASA6 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/1178016:EROM_010260 ^@ http://purl.uniprot.org/uniprot/I6ZS03 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/1178016:EROM_080360 ^@ http://purl.uniprot.org/uniprot/I6ZJN6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_081400 ^@ http://purl.uniprot.org/uniprot/I6ZUY1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_030570 ^@ http://purl.uniprot.org/uniprot/I6ZHM1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1178016:EROM_111340 ^@ http://purl.uniprot.org/uniprot/I7AH31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC13 family.|||nuclear pore complex http://togogenome.org/gene/1178016:EROM_100960 ^@ http://purl.uniprot.org/uniprot/I7ATV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/1178016:EROM_070060 ^@ http://purl.uniprot.org/uniprot/I7AS68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_031230 ^@ http://purl.uniprot.org/uniprot/I7ADT2 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/1178016:EROM_040310 ^@ http://purl.uniprot.org/uniprot/I7ADX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/1178016:EROM_100920 ^@ http://purl.uniprot.org/uniprot/I6ZKR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/1178016:EROM_021180 ^@ http://purl.uniprot.org/uniprot/I6ZHB7 ^@ Similarity ^@ Belongs to the DIM1 family. http://togogenome.org/gene/1178016:EROM_060180 ^@ http://purl.uniprot.org/uniprot/I6ZIR1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/1178016:EROM_071340 ^@ http://purl.uniprot.org/uniprot/I7AFB1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/1178016:EROM_100700 ^@ http://purl.uniprot.org/uniprot/I6ZVV5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/1178016:EROM_040910 ^@ http://purl.uniprot.org/uniprot/I6ZI18 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_010940 ^@ http://purl.uniprot.org/uniprot/I6ZGX2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/1178016:EROM_030880 ^@ http://purl.uniprot.org/uniprot/I7AM18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1178016:EROM_010240 ^@ http://purl.uniprot.org/uniprot/I7AL42 ^@ Function|||Similarity ^@ Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|||Belongs to the actin family. http://togogenome.org/gene/1178016:EROM_030960 ^@ http://purl.uniprot.org/uniprot/I7AQX5 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion|||Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/1178016:EROM_061220 ^@ http://purl.uniprot.org/uniprot/I7AN95 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/1178016:EROM_011190 ^@ http://purl.uniprot.org/uniprot/I6ZGZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_041470 ^@ http://purl.uniprot.org/uniprot/I6ZTD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/1178016:EROM_031140 ^@ http://purl.uniprot.org/uniprot/I6ZT07 ^@ Similarity ^@ Belongs to the cytidylate kinase family. Type 1 subfamily. http://togogenome.org/gene/1178016:EROM_081360 ^@ http://purl.uniprot.org/uniprot/I7ASX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_041240 ^@ http://purl.uniprot.org/uniprot/I7AE39 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/1178016:EROM_030780 ^@ http://purl.uniprot.org/uniprot/I7AM12 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/1178016:EROM_110400 ^@ http://purl.uniprot.org/uniprot/I7AU64 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1178016:EROM_100670 ^@ http://purl.uniprot.org/uniprot/I6ZKP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RRP8 family.|||S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.|||nucleolus http://togogenome.org/gene/1178016:EROM_050880 ^@ http://purl.uniprot.org/uniprot/I7AED4 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/1178016:EROM_080730 ^@ http://purl.uniprot.org/uniprot/I7ASS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/1178016:EROM_051440 ^@ http://purl.uniprot.org/uniprot/I7AMV3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1178016:EROM_081500 ^@ http://purl.uniprot.org/uniprot/I6ZUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/1178016:EROM_070110 ^@ http://purl.uniprot.org/uniprot/I7AS72 ^@ Similarity ^@ Belongs to the histidine acid phosphatase family. http://togogenome.org/gene/1178016:EROM_100080 ^@ http://purl.uniprot.org/uniprot/I6ZVQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/1178016:EROM_110960 ^@ http://purl.uniprot.org/uniprot/I6ZL75 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1178016:EROM_070650 ^@ http://purl.uniprot.org/uniprot/I6ZUG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_111210 ^@ http://purl.uniprot.org/uniprot/I7AUE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum http://togogenome.org/gene/1178016:EROM_101500 ^@ http://purl.uniprot.org/uniprot/I7AGQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/1178016:EROM_041390 ^@ http://purl.uniprot.org/uniprot/I7AE49 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/1178016:EROM_020350 ^@ http://purl.uniprot.org/uniprot/I7AD31 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1178016:EROM_021060 ^@ http://purl.uniprot.org/uniprot/I6ZSJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_110450 ^@ http://purl.uniprot.org/uniprot/I7AU69 ^@ Similarity ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_110070 ^@ http://purl.uniprot.org/uniprot/I6ZW54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAPC3/SRD2 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_031200 ^@ http://purl.uniprot.org/uniprot/I7AQY8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_020790 ^@ http://purl.uniprot.org/uniprot/I7ALK2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/1178016:EROM_071580 ^@ http://purl.uniprot.org/uniprot/I7ANP9 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/1178016:EROM_070770 ^@ http://purl.uniprot.org/uniprot/I6ZJB3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/1178016:EROM_060730 ^@ http://purl.uniprot.org/uniprot/I6ZU46 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_101180 ^@ http://purl.uniprot.org/uniprot/I6ZKU1 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/1178016:EROM_030190 ^@ http://purl.uniprot.org/uniprot/I6ZHJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/1178016:EROM_070720 ^@ http://purl.uniprot.org/uniprot/I6ZJB0 ^@ Subcellular Location Annotation ^@ Nucleus membrane|||perinuclear region http://togogenome.org/gene/1178016:EROM_040550 ^@ http://purl.uniprot.org/uniprot/I6ZHY3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM5 / TYW2 family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/1178016:EROM_081850 ^@ http://purl.uniprot.org/uniprot/I7AFT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_051170 ^@ http://purl.uniprot.org/uniprot/I6ZIK0 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_011150 ^@ http://purl.uniprot.org/uniprot/I7ALC1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/1178016:EROM_030180 ^@ http://purl.uniprot.org/uniprot/I7AQR1 ^@ Function|||Similarity ^@ Belongs to the UDPGP type 1 family.|||Plays a central role as a glucosyl donor in cellular metabolic pathways. http://togogenome.org/gene/1178016:EROM_011210 ^@ http://purl.uniprot.org/uniprot/I7ACZ3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/1178016:EROM_110790 ^@ http://purl.uniprot.org/uniprot/I6ZWB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/1178016:EROM_070020 ^@ http://purl.uniprot.org/uniprot/I6ZJ55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/1178016:EROM_060100 ^@ http://purl.uniprot.org/uniprot/I7AEK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_101670 ^@ http://purl.uniprot.org/uniprot/I7AU23 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/1178016:EROM_030550 ^@ http://purl.uniprot.org/uniprot/I6ZSW4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/1178016:EROM_050280 ^@ http://purl.uniprot.org/uniprot/I6ZTH3 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/1178016:EROM_051570 ^@ http://purl.uniprot.org/uniprot/I7ART0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1178016:EROM_050030 ^@ http://purl.uniprot.org/uniprot/I7ARE0 ^@ Similarity ^@ Belongs to the NTE family. http://togogenome.org/gene/1178016:EROM_061440 ^@ http://purl.uniprot.org/uniprot/I7AEZ5 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/1178016:EROM_041280 ^@ http://purl.uniprot.org/uniprot/I7AMG3 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/1178016:EROM_030800 ^@ http://purl.uniprot.org/uniprot/I6ZSY3 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/1178016:EROM_050210 ^@ http://purl.uniprot.org/uniprot/I7AML1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/1178016:EROM_040980 ^@ http://purl.uniprot.org/uniprot/I7AE20 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/1178016:EROM_101130 ^@ http://purl.uniprot.org/uniprot/I6ZKT6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_060700 ^@ http://purl.uniprot.org/uniprot/I6ZIZ2 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/1178016:EROM_020110 ^@ http://purl.uniprot.org/uniprot/I6ZSA2 ^@ Similarity ^@ Belongs to the lipin family. http://togogenome.org/gene/1178016:EROM_011310 ^@ http://purl.uniprot.org/uniprot/I7AD02 ^@ Similarity ^@ Belongs to the UPF0329 family. http://togogenome.org/gene/1178016:EROM_060950 ^@ http://purl.uniprot.org/uniprot/I7AS31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA40 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_070540 ^@ http://purl.uniprot.org/uniprot/I7AF49 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/1178016:EROM_061610 ^@ http://purl.uniprot.org/uniprot/I6ZUB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the folylpolyglutamate synthase family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion matrix http://togogenome.org/gene/1178016:EROM_020170 ^@ http://purl.uniprot.org/uniprot/I7AQA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_051410 ^@ http://purl.uniprot.org/uniprot/I6ZTS0 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/1178016:EROM_050610 ^@ http://purl.uniprot.org/uniprot/I6ZIE5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/1178016:EROM_110420 ^@ http://purl.uniprot.org/uniprot/I7AQ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/1178016:EROM_030310 ^@ http://purl.uniprot.org/uniprot/I7AQS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_011140 ^@ http://purl.uniprot.org/uniprot/I6ZGZ2 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/1178016:EROM_080330 ^@ http://purl.uniprot.org/uniprot/I7AFG6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_111270 ^@ http://purl.uniprot.org/uniprot/I6ZLA2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/1178016:EROM_050330 ^@ http://purl.uniprot.org/uniprot/I6ZTH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_030280 ^@ http://purl.uniprot.org/uniprot/I7ALX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_020590 ^@ http://purl.uniprot.org/uniprot/I7ALI1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1178016:EROM_050310 ^@ http://purl.uniprot.org/uniprot/I7AML8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/1178016:EROM_110640 ^@ http://purl.uniprot.org/uniprot/I6ZWA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCR4/nocturin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_010860 ^@ http://purl.uniprot.org/uniprot/I7ACW6 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1178016:EROM_100560 ^@ http://purl.uniprot.org/uniprot/I7ATR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family.|||nucleolus http://togogenome.org/gene/1178016:EROM_100780 ^@ http://purl.uniprot.org/uniprot/I7APT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_111360 ^@ http://purl.uniprot.org/uniprot/I7AUF9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_050660 ^@ http://purl.uniprot.org/uniprot/I6ZIF0 ^@ Function|||Similarity ^@ Belongs to the GPI family.|||In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. http://togogenome.org/gene/1178016:EROM_101220 ^@ http://purl.uniprot.org/uniprot/I7ATX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_040630 ^@ http://purl.uniprot.org/uniprot/I6ZT76 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/1178016:EROM_100970 ^@ http://purl.uniprot.org/uniprot/I6ZKS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ING family.|||Nucleus http://togogenome.org/gene/1178016:EROM_071200 ^@ http://purl.uniprot.org/uniprot/I6ZUK0 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/1178016:EROM_051100 ^@ http://purl.uniprot.org/uniprot/I6ZTP6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1178016:EROM_100750 ^@ http://purl.uniprot.org/uniprot/I6ZVV9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1178016:EROM_081890 ^@ http://purl.uniprot.org/uniprot/I6ZVQ0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/1178016:EROM_071130 ^@ http://purl.uniprot.org/uniprot/I7ANL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/1178016:EROM_111320 ^@ http://purl.uniprot.org/uniprot/I6ZLA7 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/1178016:EROM_020670 ^@ http://purl.uniprot.org/uniprot/I7AQF2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/1178016:EROM_081170 ^@ http://purl.uniprot.org/uniprot/I6ZJU9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/1178016:EROM_061060 ^@ http://purl.uniprot.org/uniprot/I6ZJ15 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/1178016:EROM_101070 ^@ http://purl.uniprot.org/uniprot/I7ATV9 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/1178016:EROM_041590 ^@ http://purl.uniprot.org/uniprot/I6ZI73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||Nucleus http://togogenome.org/gene/1178016:EROM_101480 ^@ http://purl.uniprot.org/uniprot/I6ZKW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/1178016:EROM_081270 ^@ http://purl.uniprot.org/uniprot/I6ZJV7 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/1178016:EROM_070320 ^@ http://purl.uniprot.org/uniprot/I6ZJ77 ^@ Similarity ^@ Belongs to the REXO1/REXO3 family. http://togogenome.org/gene/1178016:EROM_030600 ^@ http://purl.uniprot.org/uniprot/I6ZSW9 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/1178016:EROM_050980 ^@ http://purl.uniprot.org/uniprot/I7AMR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_050910 ^@ http://purl.uniprot.org/uniprot/I7ARL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_030070 ^@ http://purl.uniprot.org/uniprot/I6ZSR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_081070 ^@ http://purl.uniprot.org/uniprot/I6ZJU0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/1178016:EROM_111660 ^@ http://purl.uniprot.org/uniprot/I7AUK7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1178016:EROM_061030 ^@ http://purl.uniprot.org/uniprot/I7AEW4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/1178016:EROM_101200 ^@ http://purl.uniprot.org/uniprot/I7AGN0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/1178016:EROM_101330 ^@ http://purl.uniprot.org/uniprot/I6ZKV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/1178016:EROM_031090 ^@ http://purl.uniprot.org/uniprot/I6ZT03 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/1178016:EROM_111560 ^@ http://purl.uniprot.org/uniprot/I7AUK2 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/1178016:EROM_041410 ^@ http://purl.uniprot.org/uniprot/I7ARB4 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1178016:EROM_041070 ^@ http://purl.uniprot.org/uniprot/I7AME4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/1178016:EROM_110240 ^@ http://purl.uniprot.org/uniprot/I7AU49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/1178016:EROM_041120 ^@ http://purl.uniprot.org/uniprot/I7AME9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_020400 ^@ http://purl.uniprot.org/uniprot/I7AD35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anamorsin family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_061200 ^@ http://purl.uniprot.org/uniprot/I7AS46 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/1178016:EROM_101250 ^@ http://purl.uniprot.org/uniprot/I7AGN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1178016:EROM_101060 ^@ http://purl.uniprot.org/uniprot/I6ZVY2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_051060 ^@ http://purl.uniprot.org/uniprot/I7ARN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/1178016:EROM_010030 ^@ http://purl.uniprot.org/uniprot/I6ZGN6 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/1178016:EROM_080820 ^@ http://purl.uniprot.org/uniprot/I7AFJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_050740 ^@ http://purl.uniprot.org/uniprot/I6ZTL3 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1178016:EROM_050370 ^@ http://purl.uniprot.org/uniprot/I7AE97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Nucleus http://togogenome.org/gene/1178016:EROM_011030 ^@ http://purl.uniprot.org/uniprot/I7AQ57 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/1178016:EROM_040730 ^@ http://purl.uniprot.org/uniprot/I6ZT84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_111650 ^@ http://purl.uniprot.org/uniprot/I6ZWK3 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/1178016:EROM_080200 ^@ http://purl.uniprot.org/uniprot/I7ASM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/1178016:EROM_111890 ^@ http://purl.uniprot.org/uniprot/I7AHA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC5 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_101600 ^@ http://purl.uniprot.org/uniprot/I7AGR4 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/1178016:EROM_111150 ^@ http://purl.uniprot.org/uniprot/I6ZWE8 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/1178016:EROM_070930 ^@ http://purl.uniprot.org/uniprot/I7ANJ4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. http://togogenome.org/gene/1178016:EROM_040070 ^@ http://purl.uniprot.org/uniprot/I6ZHU4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/1178016:EROM_111810 ^@ http://purl.uniprot.org/uniprot/I7AUL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/1178016:EROM_100380 ^@ http://purl.uniprot.org/uniprot/I7APQ2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/1178016:EROM_101620 ^@ http://purl.uniprot.org/uniprot/I7AU19 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1178016:EROM_081820 ^@ http://purl.uniprot.org/uniprot/I6ZK09 ^@ Function ^@ Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. http://togogenome.org/gene/1178016:EROM_050250 ^@ http://purl.uniprot.org/uniprot/I6ZIB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dUTPase family.|||Homotrimer.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1178016:EROM_110750 ^@ http://purl.uniprot.org/uniprot/I7AU98 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/1178016:EROM_100180 ^@ http://purl.uniprot.org/uniprot/I7AGE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Sterol O-acyltransferase that catalyzes the formation of stery esters. http://togogenome.org/gene/1178016:EROM_020010 ^@ http://purl.uniprot.org/uniprot/I6ZS95 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1178016:EROM_050520 ^@ http://purl.uniprot.org/uniprot/I7AEA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_070970 ^@ http://purl.uniprot.org/uniprot/I6ZJD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/1178016:EROM_110870 ^@ http://purl.uniprot.org/uniprot/I7AQB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_060780 ^@ http://purl.uniprot.org/uniprot/I6ZU48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SSU72 phosphatase family.|||Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.|||Component of the cleavage and polyadenylation factor (CPF) complex.|||Nucleus|||Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). http://togogenome.org/gene/1178016:EROM_100190 ^@ http://purl.uniprot.org/uniprot/I6ZVR3 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/1178016:EROM_100390 ^@ http://purl.uniprot.org/uniprot/I7AGG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Membrane http://togogenome.org/gene/1178016:EROM_081320 ^@ http://purl.uniprot.org/uniprot/I6ZJW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Membrane http://togogenome.org/gene/1178016:EROM_050950 ^@ http://purl.uniprot.org/uniprot/I6ZTN2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/1178016:EROM_110010 ^@ http://purl.uniprot.org/uniprot/I6ZW48 ^@ Function|||Similarity ^@ Belongs to the DNA glycosylase MPG family.|||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. http://togogenome.org/gene/1178016:EROM_021210 ^@ http://purl.uniprot.org/uniprot/I6ZSL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Endoplasmic reticulum membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/1178016:EROM_080180 ^@ http://purl.uniprot.org/uniprot/I7AFF6 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/1178016:EROM_010540 ^@ http://purl.uniprot.org/uniprot/I6ZGT5 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/1178016:EROM_050270 ^@ http://purl.uniprot.org/uniprot/I7AE90 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/1178016:EROM_070700 ^@ http://purl.uniprot.org/uniprot/I6ZUG3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_040090 ^@ http://purl.uniprot.org/uniprot/I7ADV8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/1178016:EROM_030240 ^@ http://purl.uniprot.org/uniprot/I7ALX1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1178016:EROM_010290 ^@ http://purl.uniprot.org/uniprot/I7AL47 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/1178016:EROM_050710 ^@ http://purl.uniprot.org/uniprot/I6ZIF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/1178016:EROM_050220 ^@ http://purl.uniprot.org/uniprot/I7AE86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/1178016:EROM_030330 ^@ http://purl.uniprot.org/uniprot/I7ALY0 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1178016:EROM_031290 ^@ http://purl.uniprot.org/uniprot/I6ZT17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/1178016:EROM_051310 ^@ http://purl.uniprot.org/uniprot/I6ZTR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1178016:EROM_080580 ^@ http://purl.uniprot.org/uniprot/I6ZJQ4 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/1178016:EROM_011060 ^@ http://purl.uniprot.org/uniprot/I7ACY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1178016:EROM_100630 ^@ http://purl.uniprot.org/uniprot/I7APS4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_030390 ^@ http://purl.uniprot.org/uniprot/I7ADL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/1178016:EROM_071220 ^@ http://purl.uniprot.org/uniprot/I6ZJF5 ^@ Function ^@ Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins). http://togogenome.org/gene/1178016:EROM_071350 ^@ http://purl.uniprot.org/uniprot/I6ZUK9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_111440 ^@ http://purl.uniprot.org/uniprot/I7AH56 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/1178016:EROM_100900 ^@ http://purl.uniprot.org/uniprot/I6ZVX2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_040350 ^@ http://purl.uniprot.org/uniprot/I7AM88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/1178016:EROM_041040 ^@ http://purl.uniprot.org/uniprot/I6ZTA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyltransferase 2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum|||Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. http://togogenome.org/gene/1178016:EROM_081055 ^@ http://purl.uniprot.org/uniprot/I7ANZ9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/1178016:EROM_101420 ^@ http://purl.uniprot.org/uniprot/I7ATZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_031260 ^@ http://purl.uniprot.org/uniprot/I6ZHS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_060350 ^@ http://purl.uniprot.org/uniprot/I7AN29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dUTPase family.|||Homotrimer.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1178016:EROM_060250 ^@ http://purl.uniprot.org/uniprot/I7AEL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_071710 ^@ http://purl.uniprot.org/uniprot/I7ASK9 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/1178016:EROM_010710 ^@ http://purl.uniprot.org/uniprot/I7ACV3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/1178016:EROM_070510 ^@ http://purl.uniprot.org/uniprot/I7ASA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_081980 ^@ http://purl.uniprot.org/uniprot/I7AT33 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/1178016:EROM_020960 ^@ http://purl.uniprot.org/uniprot/I6ZSI8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_111920 ^@ http://purl.uniprot.org/uniprot/I6ZLI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STE12 transcription factor family.|||Nucleus http://togogenome.org/gene/1178016:EROM_020810 ^@ http://purl.uniprot.org/uniprot/I6ZSH4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/1178016:EROM_010880 ^@ http://purl.uniprot.org/uniprot/I7AQ43 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1178016:EROM_060980 ^@ http://purl.uniprot.org/uniprot/I7AEV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.|||nucleolus http://togogenome.org/gene/1178016:EROM_110620 ^@ http://purl.uniprot.org/uniprot/I7AQ90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNO1 family.|||Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).|||Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species. http://togogenome.org/gene/1178016:EROM_071280 ^@ http://purl.uniprot.org/uniprot/I7ANM4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. http://togogenome.org/gene/1178016:EROM_111410 ^@ http://purl.uniprot.org/uniprot/I7AUG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Forms a complex with TRM82.|||Nucleus http://togogenome.org/gene/1178016:EROM_100300 ^@ http://purl.uniprot.org/uniprot/I7ATP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Membrane http://togogenome.org/gene/1178016:EROM_050020 ^@ http://purl.uniprot.org/uniprot/I6ZTF3 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_111350 ^@ http://purl.uniprot.org/uniprot/I6ZWG3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. http://togogenome.org/gene/1178016:EROM_030500 ^@ http://purl.uniprot.org/uniprot/I6ZSW0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_051160 ^@ http://purl.uniprot.org/uniprot/I7ARP2 ^@ Similarity ^@ Belongs to the Clp1 family. NOL9/GRC3 subfamily. http://togogenome.org/gene/1178016:EROM_020440 ^@ http://purl.uniprot.org/uniprot/I7ALG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_040990 ^@ http://purl.uniprot.org/uniprot/I6ZTA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_030360 ^@ http://purl.uniprot.org/uniprot/I7AQS8 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/1178016:EROM_020530 ^@ http://purl.uniprot.org/uniprot/I6ZH57 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL5 family.|||Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. http://togogenome.org/gene/1178016:EROM_031120 ^@ http://purl.uniprot.org/uniprot/I7AM32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGC family.|||Membrane http://togogenome.org/gene/1178016:EROM_111500 ^@ http://purl.uniprot.org/uniprot/I6ZWJ3 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/1178016:EROM_020890 ^@ http://purl.uniprot.org/uniprot/I7ALL4 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/1178016:EROM_021240 ^@ http://purl.uniprot.org/uniprot/I7ALQ0 ^@ Similarity ^@ Belongs to the V-ATPase G subunit family. http://togogenome.org/gene/1178016:EROM_030610 ^@ http://purl.uniprot.org/uniprot/I7AQV0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/1178016:EROM_030680 ^@ http://purl.uniprot.org/uniprot/I7AM06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the URM1 family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_040770 ^@ http://purl.uniprot.org/uniprot/I7AE06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP4 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_041610 ^@ http://purl.uniprot.org/uniprot/I7AE67 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_110630 ^@ http://purl.uniprot.org/uniprot/I7AGW9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/1178016:EROM_050580 ^@ http://purl.uniprot.org/uniprot/I6ZTJ9 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/1178016:EROM_110830 ^@ http://purl.uniprot.org/uniprot/I7AGY5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_031240 ^@ http://purl.uniprot.org/uniprot/I6ZT13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_100800 ^@ http://purl.uniprot.org/uniprot/I6ZVW2 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1178016:EROM_110180 ^@ http://purl.uniprot.org/uniprot/I7AU44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 31 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_110770 ^@ http://purl.uniprot.org/uniprot/I7AQA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_040850 ^@ http://purl.uniprot.org/uniprot/I6ZI13 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/1178016:EROM_110230 ^@ http://purl.uniprot.org/uniprot/I6ZW69 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/1178016:EROM_021340 ^@ http://purl.uniprot.org/uniprot/I7ALR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/1178016:EROM_070750 ^@ http://purl.uniprot.org/uniprot/I6ZUG7 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/1178016:EROM_050680 ^@ http://purl.uniprot.org/uniprot/I7AEC1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/1178016:EROM_030150 ^@ http://purl.uniprot.org/uniprot/I7ALW0 ^@ Similarity ^@ Belongs to the CHS7 family. http://togogenome.org/gene/1178016:EROM_030380 ^@ http://purl.uniprot.org/uniprot/I7ALY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/1178016:EROM_081490 ^@ http://purl.uniprot.org/uniprot/I7AFP7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/1178016:EROM_070300 ^@ http://purl.uniprot.org/uniprot/I6ZUD4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/1178016:EROM_040290 ^@ http://purl.uniprot.org/uniprot/I6ZHW1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL27 family. http://togogenome.org/gene/1178016:EROM_080860 ^@ http://purl.uniprot.org/uniprot/I7ANY0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_051600 ^@ http://purl.uniprot.org/uniprot/I7AEJ1 ^@ Similarity ^@ Belongs to the activator 1 large subunit family. http://togogenome.org/gene/1178016:EROM_081200 ^@ http://purl.uniprot.org/uniprot/I6ZUW5 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/1178016:EROM_100140 ^@ http://purl.uniprot.org/uniprot/I7ATN1 ^@ Similarity ^@ Belongs to the RNase PH family. http://togogenome.org/gene/1178016:EROM_111220 ^@ http://purl.uniprot.org/uniprot/I6ZL98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_050040 ^@ http://purl.uniprot.org/uniprot/I6ZI90 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_040180 ^@ http://purl.uniprot.org/uniprot/I7AR18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_041680 ^@ http://purl.uniprot.org/uniprot/I6ZI85 ^@ Similarity ^@ Belongs to the UPF0328 family. http://togogenome.org/gene/1178016:EROM_021160 ^@ http://purl.uniprot.org/uniprot/I6ZSK9 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/1178016:EROM_071270 ^@ http://purl.uniprot.org/uniprot/I6ZJF9 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/1178016:EROM_041180 ^@ http://purl.uniprot.org/uniprot/I7AMF3 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/1178016:EROM_081210 ^@ http://purl.uniprot.org/uniprot/I7ASW3 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/1178016:EROM_070790 ^@ http://purl.uniprot.org/uniprot/I7AF69 ^@ Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_030260 ^@ http://purl.uniprot.org/uniprot/I6ZSU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/1178016:EROM_071700 ^@ http://purl.uniprot.org/uniprot/I6ZUN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS4/SLD5 family.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/1178016:EROM_031340 ^@ http://purl.uniprot.org/uniprot/I6ZT21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H3 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_070120 ^@ http://purl.uniprot.org/uniprot/I6ZJ62 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_051130 ^@ http://purl.uniprot.org/uniprot/I7AMS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LTN1 family.|||Component of the ribosome quality control complex (RQC).|||E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. http://togogenome.org/gene/1178016:EROM_021280 ^@ http://purl.uniprot.org/uniprot/I6ZHC5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 37 family. http://togogenome.org/gene/1178016:EROM_101360 ^@ http://purl.uniprot.org/uniprot/I6ZW14 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_101170 ^@ http://purl.uniprot.org/uniprot/I7ATX0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/1178016:EROM_060310 ^@ http://purl.uniprot.org/uniprot/I6ZU00 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/1178016:EROM_100500 ^@ http://purl.uniprot.org/uniprot/I6ZVU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/1178016:EROM_050560 ^@ http://purl.uniprot.org/uniprot/I7AMN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/1178016:EROM_040010 ^@ http://purl.uniprot.org/uniprot/I6ZHU1 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1178016:EROM_061520 ^@ http://purl.uniprot.org/uniprot/I6ZJ47 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/1178016:EROM_100660 ^@ http://purl.uniprot.org/uniprot/I7ATS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NGG1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_110970 ^@ http://purl.uniprot.org/uniprot/I7AQC3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ERF4 family.|||Endoplasmic reticulum membrane|||Interacts with ERF2. http://togogenome.org/gene/1178016:EROM_070740 ^@ http://purl.uniprot.org/uniprot/I7AF64 ^@ Similarity ^@ Belongs to the SEC3 family. http://togogenome.org/gene/1178016:EROM_041300 ^@ http://purl.uniprot.org/uniprot/I6ZTC5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/1178016:EROM_030470 ^@ http://purl.uniprot.org/uniprot/I6ZHL3 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/1178016:EROM_110670 ^@ http://purl.uniprot.org/uniprot/I7AQ94 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/1178016:EROM_031370 ^@ http://purl.uniprot.org/uniprot/I7AM50 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/1178016:EROM_111770 ^@ http://purl.uniprot.org/uniprot/I6ZLG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/1178016:EROM_031050 ^@ http://purl.uniprot.org/uniprot/I7AQX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_010110 ^@ http://purl.uniprot.org/uniprot/I6ZRZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPP10 family.|||nucleolus http://togogenome.org/gene/1178016:EROM_111300 ^@ http://purl.uniprot.org/uniprot/I6ZWF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EST3 family.|||Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.|||Nucleus|||telomere http://togogenome.org/gene/1178016:EROM_081090 ^@ http://purl.uniprot.org/uniprot/I7AFL3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1178016:EROM_100470 ^@ http://purl.uniprot.org/uniprot/I6ZKM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||Nucleus http://togogenome.org/gene/1178016:EROM_050790 ^@ http://purl.uniprot.org/uniprot/I6ZTL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_021050 ^@ http://purl.uniprot.org/uniprot/I7ADA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_011120 ^@ http://purl.uniprot.org/uniprot/I6ZS77 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/1178016:EROM_071530 ^@ http://purl.uniprot.org/uniprot/I7ANP5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/1178016:EROM_101300 ^@ http://purl.uniprot.org/uniprot/I7AGN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_030410 ^@ http://purl.uniprot.org/uniprot/I7AQT2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1178016:EROM_030205 ^@ http://purl.uniprot.org/uniprot/I7ADK4 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1178016:EROM_050380 ^@ http://purl.uniprot.org/uniprot/I6ZTI2 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/1178016:EROM_061560 ^@ http://purl.uniprot.org/uniprot/I7AS62 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1178016:EROM_080130 ^@ http://purl.uniprot.org/uniprot/I6ZUP8 ^@ Function|||Similarity ^@ Belongs to the WD repeat SEC31 family.|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. http://togogenome.org/gene/1178016:EROM_010990 ^@ http://purl.uniprot.org/uniprot/I6ZGX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1178016:EROM_100720 ^@ http://purl.uniprot.org/uniprot/I6ZKP7 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/1178016:EROM_101570 ^@ http://purl.uniprot.org/uniprot/I7AU13 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1178016:EROM_070830 ^@ http://purl.uniprot.org/uniprot/I7ANI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB4 family.|||Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.|||Nucleus http://togogenome.org/gene/1178016:EROM_110100 ^@ http://purl.uniprot.org/uniprot/I7AQ40 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/1178016:EROM_021000 ^@ http://purl.uniprot.org/uniprot/I7ADA0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_101230 ^@ http://purl.uniprot.org/uniprot/I6ZKU6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_031320 ^@ http://purl.uniprot.org/uniprot/I7AM46 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1178016:EROM_060890 ^@ http://purl.uniprot.org/uniprot/I6ZU58 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1178016:EROM_020390 ^@ http://purl.uniprot.org/uniprot/I7ALG2 ^@ Function|||Similarity ^@ Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.|||Belongs to the proteasome subunit S1 family. http://togogenome.org/gene/1178016:EROM_081310 ^@ http://purl.uniprot.org/uniprot/I7ASX2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/1178016:EROM_080980 ^@ http://purl.uniprot.org/uniprot/I6ZJT2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_041170 ^@ http://purl.uniprot.org/uniprot/I6ZI36 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/1178016:EROM_111880 ^@ http://purl.uniprot.org/uniprot/I7AQN1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/1178016:EROM_041230 ^@ http://purl.uniprot.org/uniprot/I7AMF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/1178016:EROM_101010 ^@ http://purl.uniprot.org/uniprot/I6ZVX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF6 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_020340 ^@ http://purl.uniprot.org/uniprot/I7ALG0 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/1178016:EROM_051010 ^@ http://purl.uniprot.org/uniprot/I7ARM8 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/1178016:EROM_100940 ^@ http://purl.uniprot.org/uniprot/I7AGK9 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/1178016:EROM_030200 ^@ http://purl.uniprot.org/uniprot/I7ALW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SKP1 family.|||Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.|||Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/1178016:EROM_040720 ^@ http://purl.uniprot.org/uniprot/I7AE02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/1178016:EROM_010400 ^@ http://purl.uniprot.org/uniprot/I7ACS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat ELP2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_060880 ^@ http://purl.uniprot.org/uniprot/I7AEV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_051390 ^@ http://purl.uniprot.org/uniprot/I7AMU8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/1178016:EROM_051270 ^@ http://purl.uniprot.org/uniprot/I6ZIL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/1178016:EROM_110090 ^@ http://purl.uniprot.org/uniprot/I6ZKZ6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_040600 ^@ http://purl.uniprot.org/uniprot/I6ZHY8 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/1178016:EROM_100150 ^@ http://purl.uniprot.org/uniprot/I6ZKK8 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1178016:EROM_110720 ^@ http://purl.uniprot.org/uniprot/I7AQ99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/1178016:EROM_051500 ^@ http://purl.uniprot.org/uniprot/I7AEI2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1178016:EROM_051380 ^@ http://purl.uniprot.org/uniprot/I6ZIM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.|||Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.|||Cytoplasm|||P-body http://togogenome.org/gene/1178016:EROM_070250 ^@ http://purl.uniprot.org/uniprot/I6ZUD0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1178016:EROM_051650 ^@ http://purl.uniprot.org/uniprot/I6ZW48 ^@ Function|||Similarity ^@ Belongs to the DNA glycosylase MPG family.|||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. http://togogenome.org/gene/1178016:EROM_040840 ^@ http://purl.uniprot.org/uniprot/I7AR69 ^@ Similarity|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1178016:EROM_020250 ^@ http://purl.uniprot.org/uniprot/I7AD22 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_100220 ^@ http://purl.uniprot.org/uniprot/I7APP1 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/1178016:EROM_110530 ^@ http://purl.uniprot.org/uniprot/I7AGV8 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/1178016:EROM_010280 ^@ http://purl.uniprot.org/uniprot/I6ZGR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_040270 ^@ http://purl.uniprot.org/uniprot/I6ZT48 ^@ Similarity ^@ Belongs to the proteasome subunit S2 family. http://togogenome.org/gene/1178016:EROM_080070 ^@ http://purl.uniprot.org/uniprot/I7AFE8 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/1178016:EROM_081570 ^@ http://purl.uniprot.org/uniprot/I6ZJY4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/1178016:EROM_020150 ^@ http://purl.uniprot.org/uniprot/I7AD13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/1178016:EROM_071650 ^@ http://purl.uniprot.org/uniprot/I6ZUN0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_111110 ^@ http://purl.uniprot.org/uniprot/I6ZL90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/1178016:EROM_081790 ^@ http://purl.uniprot.org/uniprot/I7AFS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_071320 ^@ http://purl.uniprot.org/uniprot/I6ZJG4 ^@ Function|||Similarity ^@ Component of the 60S subunit of the ribosome.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/1178016:EROM_060650 ^@ http://purl.uniprot.org/uniprot/I7AN56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1178016:EROM_071560 ^@ http://purl.uniprot.org/uniprot/I7ASJ5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_031250 ^@ http://purl.uniprot.org/uniprot/I7AQZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_021010 ^@ http://purl.uniprot.org/uniprot/I6ZSJ3 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/1178016:EROM_060810 ^@ http://purl.uniprot.org/uniprot/I7AN67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_010750 ^@ http://purl.uniprot.org/uniprot/I7AL87 ^@ Similarity ^@ Belongs to the MBF1 family. http://togogenome.org/gene/1178016:EROM_110170 ^@ http://purl.uniprot.org/uniprot/I6ZW64 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/1178016:EROM_110330 ^@ http://purl.uniprot.org/uniprot/I7AGU4 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/1178016:EROM_101100 ^@ http://purl.uniprot.org/uniprot/I7AGM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||DNA polymerase II participates in chromosomal DNA replication.|||Nucleus http://togogenome.org/gene/1178016:EROM_061390 ^@ http://purl.uniprot.org/uniprot/I7AEZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS2/PSF2 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_021070 ^@ http://purl.uniprot.org/uniprot/I7AQI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BBP/SF1 family.|||Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.|||Nucleus http://togogenome.org/gene/1178016:EROM_111120 ^@ http://purl.uniprot.org/uniprot/I7AQD9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_060270 ^@ http://purl.uniprot.org/uniprot/I7ARW2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_061290 ^@ http://purl.uniprot.org/uniprot/I7AN99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/1178016:EROM_081440 ^@ http://purl.uniprot.org/uniprot/I7AFP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYG1 (TC 2.A.94) family.|||Membrane http://togogenome.org/gene/1178016:EROM_031220 ^@ http://purl.uniprot.org/uniprot/I7AM39 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/1178016:EROM_110390 ^@ http://purl.uniprot.org/uniprot/I6ZW82 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_020710 ^@ http://purl.uniprot.org/uniprot/I6ZSG2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/1178016:EROM_040680 ^@ http://purl.uniprot.org/uniprot/I6ZT79 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/1178016:EROM_070410 ^@ http://purl.uniprot.org/uniprot/I7AS93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/1178016:EROM_061450 ^@ http://purl.uniprot.org/uniprot/I6ZU99 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/1178016:EROM_111910 ^@ http://purl.uniprot.org/uniprot/I7AUM6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_011230 ^@ http://purl.uniprot.org/uniprot/I7AQ78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_061010 ^@ http://purl.uniprot.org/uniprot/I6ZJ11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the CWC24 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/1178016:EROM_070880 ^@ http://purl.uniprot.org/uniprot/I7ANI9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/1178016:EROM_082020 ^@ http://purl.uniprot.org/uniprot/I6ZV42 ^@ Similarity ^@ Belongs to the UPF0328 family. http://togogenome.org/gene/1178016:EROM_111750 ^@ http://purl.uniprot.org/uniprot/I6ZWL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_061490 ^@ http://purl.uniprot.org/uniprot/I7AEZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_021150 ^@ http://purl.uniprot.org/uniprot/I7ADB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND1 (condensin subunit 1) family.|||Chromosome|||Nucleus http://togogenome.org/gene/1178016:EROM_020970 ^@ http://purl.uniprot.org/uniprot/I7AQH9 ^@ Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family.|||Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences. http://togogenome.org/gene/1178016:EROM_071660 ^@ http://purl.uniprot.org/uniprot/I7ASK5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_080220 ^@ http://purl.uniprot.org/uniprot/I7ANS9 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/1178016:EROM_060170 ^@ http://purl.uniprot.org/uniprot/I7ARV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/1178016:EROM_010660 ^@ http://purl.uniprot.org/uniprot/I7ACU8 ^@ Similarity ^@ In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1178016:EROM_020140 ^@ http://purl.uniprot.org/uniprot/I7ALE1 ^@ Similarity ^@ Belongs to the IPP isomerase type 1 family. http://togogenome.org/gene/1178016:EROM_040960 ^@ http://purl.uniprot.org/uniprot/I6ZI22 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/1178016:EROM_081280 ^@ http://purl.uniprot.org/uniprot/I7AP17 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_061360 ^@ http://purl.uniprot.org/uniprot/I7AS54 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/1178016:EROM_030720 ^@ http://purl.uniprot.org/uniprot/I6ZHN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/1178016:EROM_101690 ^@ http://purl.uniprot.org/uniprot/I7AQ31 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_010460 ^@ http://purl.uniprot.org/uniprot/I7ACS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.|||Nucleus http://togogenome.org/gene/1178016:EROM_100290 ^@ http://purl.uniprot.org/uniprot/I6ZVS4 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/1178016:EROM_100620 ^@ http://purl.uniprot.org/uniprot/I6ZKP0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24 family.|||Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/1178016:EROM_060120 ^@ http://purl.uniprot.org/uniprot/I7ARU9 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/1178016:EROM_080740 ^@ http://purl.uniprot.org/uniprot/I6ZJR8 ^@ Similarity ^@ Belongs to the type-1 OGG1 family. http://togogenome.org/gene/1178016:EROM_030275 ^@ http://purl.uniprot.org/uniprot/I6ZHK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1178016:EROM_111840 ^@ http://purl.uniprot.org/uniprot/I7AHA1 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/1178016:EROM_111160 ^@ http://purl.uniprot.org/uniprot/I7AUD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.|||Nucleus http://togogenome.org/gene/1178016:EROM_080840 ^@ http://purl.uniprot.org/uniprot/I7AST1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/1178016:EROM_110660 ^@ http://purl.uniprot.org/uniprot/I6ZL47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Cytoplasm|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/1178016:EROM_070290 ^@ http://purl.uniprot.org/uniprot/I7AF31 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1178016:EROM_050700 ^@ http://purl.uniprot.org/uniprot/I7ARK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGW family.|||Membrane http://togogenome.org/gene/1178016:EROM_040760 ^@ http://purl.uniprot.org/uniprot/I7AMC0 ^@ Similarity ^@ Belongs to the NOP5/NOP56 family. http://togogenome.org/gene/1178016:EROM_100540 ^@ http://purl.uniprot.org/uniprot/I7AGH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly. http://togogenome.org/gene/1178016:EROM_081470 ^@ http://purl.uniprot.org/uniprot/I6ZJX3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_101090 ^@ http://purl.uniprot.org/uniprot/I7APW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.|||Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1178016:EROM_051330 ^@ http://purl.uniprot.org/uniprot/I6ZIL6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1178016:EROM_040940 ^@ http://purl.uniprot.org/uniprot/I6ZTA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_080600 ^@ http://purl.uniprot.org/uniprot/I7AFI2 ^@ Similarity ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_021400 ^@ http://purl.uniprot.org/uniprot/I7ADE1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Mitochondrion|||Monomer. http://togogenome.org/gene/1178016:EROM_061050 ^@ http://purl.uniprot.org/uniprot/I7AS36 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/1178016:EROM_040480 ^@ http://purl.uniprot.org/uniprot/I6ZT63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.|||nucleolus http://togogenome.org/gene/1178016:EROM_010180 ^@ http://purl.uniprot.org/uniprot/I6ZGQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Membrane|||Probably involved in transport through the plasma membrane. http://togogenome.org/gene/1178016:EROM_040520 ^@ http://purl.uniprot.org/uniprot/I7ADY8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1178016:EROM_021200 ^@ http://purl.uniprot.org/uniprot/I7ADC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND2 (condensin subunit 2) family.|||Chromosome|||Cytoplasm http://togogenome.org/gene/1178016:EROM_060190 ^@ http://purl.uniprot.org/uniprot/I7AMY5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_100690 ^@ http://purl.uniprot.org/uniprot/I7AGI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/1178016:EROM_110740 ^@ http://purl.uniprot.org/uniprot/I6ZWB2 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/1178016:EROM_010930 ^@ http://purl.uniprot.org/uniprot/I7AQ48 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/1178016:EROM_060660 ^@ http://purl.uniprot.org/uniprot/I7AET8 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1178016:EROM_060840 ^@ http://purl.uniprot.org/uniprot/I7AS25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_101650 ^@ http://purl.uniprot.org/uniprot/I7AGR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/1178016:EROM_020990 ^@ http://purl.uniprot.org/uniprot/I7ALM3 ^@ Similarity ^@ In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/1178016:EROM_050930 ^@ http://purl.uniprot.org/uniprot/I7AMQ9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/1178016:EROM_071430 ^@ http://purl.uniprot.org/uniprot/I7ANN7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1178016:EROM_051460 ^@ http://purl.uniprot.org/uniprot/I6ZTS5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1178016:EROM_100130 ^@ http://purl.uniprot.org/uniprot/I6ZVR0 ^@ Similarity ^@ Belongs to the NFYB/HAP3 subunit family. http://togogenome.org/gene/1178016:EROM_081660 ^@ http://purl.uniprot.org/uniprot/I7AT04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Nucleus|||The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.|||centromere http://togogenome.org/gene/1178016:EROM_061480 ^@ http://purl.uniprot.org/uniprot/I7ANB1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_081110 ^@ http://purl.uniprot.org/uniprot/I7ASV3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/1178016:EROM_100200 ^@ http://purl.uniprot.org/uniprot/I7ATN5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/1178016:EROM_081760 ^@ http://purl.uniprot.org/uniprot/I7AT13 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/1178016:EROM_021300 ^@ http://purl.uniprot.org/uniprot/I7ADD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/1178016:EROM_030640 ^@ http://purl.uniprot.org/uniprot/I7ADN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM NCBP2 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_101470 ^@ http://purl.uniprot.org/uniprot/I7AU02 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS30 family. http://togogenome.org/gene/1178016:EROM_111380 ^@ http://purl.uniprot.org/uniprot/I7AQG3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_031430 ^@ http://purl.uniprot.org/uniprot/I7ADU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_021310 ^@ http://purl.uniprot.org/uniprot/I6ZSM4 ^@ Function ^@ Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle. http://togogenome.org/gene/1178016:EROM_081800 ^@ http://purl.uniprot.org/uniprot/I6ZV21 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/1178016:EROM_111700 ^@ http://purl.uniprot.org/uniprot/I6ZWK7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1178016:EROM_040930 ^@ http://purl.uniprot.org/uniprot/I7AE16 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_041110 ^@ http://purl.uniprot.org/uniprot/I6ZI30 ^@ Similarity ^@ Belongs to the glycosyltransferase 15 family. http://togogenome.org/gene/1178016:EROM_111820 ^@ http://purl.uniprot.org/uniprot/I6ZLH3 ^@ Function ^@ The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. http://togogenome.org/gene/1178016:EROM_080020 ^@ http://purl.uniprot.org/uniprot/I7AFE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_110430 ^@ http://purl.uniprot.org/uniprot/I7AGV1 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/1178016:EROM_101580 ^@ http://purl.uniprot.org/uniprot/I6ZKX7 ^@ Similarity ^@ Belongs to the enolase family. http://togogenome.org/gene/1178016:EROM_010950 ^@ http://purl.uniprot.org/uniprot/I7ALA7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1178016:EROM_040420 ^@ http://purl.uniprot.org/uniprot/I7ADY2 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.|||Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. http://togogenome.org/gene/1178016:EROM_041150 ^@ http://purl.uniprot.org/uniprot/I6ZTB6 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/1178016:EROM_071080 ^@ http://purl.uniprot.org/uniprot/I7ANK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecQ subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_051530 ^@ http://purl.uniprot.org/uniprot/I6ZIN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_031400 ^@ http://purl.uniprot.org/uniprot/I7AR00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/1178016:EROM_021110 ^@ http://purl.uniprot.org/uniprot/I6ZSK3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_110710 ^@ http://purl.uniprot.org/uniprot/I6ZL50 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_040130 ^@ http://purl.uniprot.org/uniprot/I6ZHU9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane|||May function both as a monomer and a homodimer. http://togogenome.org/gene/1178016:EROM_011300 ^@ http://purl.uniprot.org/uniprot/I7ALD0 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1178016:EROM_021130 ^@ http://purl.uniprot.org/uniprot/I6ZHB3 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/1178016:EROM_050810 ^@ http://purl.uniprot.org/uniprot/I6ZIG4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1178016:EROM_070900 ^@ http://purl.uniprot.org/uniprot/I6ZUH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_040580 ^@ http://purl.uniprot.org/uniprot/I6ZT72 ^@ Similarity ^@ Belongs to the SWI5/SAE3 family. http://togogenome.org/gene/1178016:EROM_080660 ^@ http://purl.uniprot.org/uniprot/I7AFI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/1178016:EROM_040220 ^@ http://purl.uniprot.org/uniprot/I6ZT44 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/1178016:EROM_051590 ^@ http://purl.uniprot.org/uniprot/I7AMW5 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1178016:EROM_080390 ^@ http://purl.uniprot.org/uniprot/I6ZUS0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1178016:EROM_051090 ^@ http://purl.uniprot.org/uniprot/I7AEE9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_020430 ^@ http://purl.uniprot.org/uniprot/I6ZH48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_111240 ^@ http://purl.uniprot.org/uniprot/I7AH22 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/1178016:EROM_031270 ^@ http://purl.uniprot.org/uniprot/I7AM43 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_010210 ^@ http://purl.uniprot.org/uniprot/I6ZRZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CPSF4/YTH1 family.|||Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.|||Nucleus http://togogenome.org/gene/1178016:EROM_030170 ^@ http://purl.uniprot.org/uniprot/I6ZST4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/1178016:EROM_030050 ^@ http://purl.uniprot.org/uniprot/I7ALU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TPT transporter family. SLC35D subfamily.|||Cytoplasmic vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homooligomer.|||Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.|||Membrane http://togogenome.org/gene/1178016:EROM_110810 ^@ http://purl.uniprot.org/uniprot/I6ZL61 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/1178016:EROM_030010 ^@ http://purl.uniprot.org/uniprot/I7ADE8 ^@ Similarity ^@ Belongs to the UPF0328 family. http://togogenome.org/gene/1178016:EROM_071260 ^@ http://purl.uniprot.org/uniprot/I7ASG8 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/1178016:EROM_041140 ^@ http://purl.uniprot.org/uniprot/I7AE30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/1178016:EROM_010760 ^@ http://purl.uniprot.org/uniprot/I7ACV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HOP2 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_070810 ^@ http://purl.uniprot.org/uniprot/I7ASC6 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/1178016:EROM_020850 ^@ http://purl.uniprot.org/uniprot/I7AD84 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1178016:EROM_100120 ^@ http://purl.uniprot.org/uniprot/I7AGE0 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1178016:EROM_030930 ^@ http://purl.uniprot.org/uniprot/I7AM20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_040500 ^@ http://purl.uniprot.org/uniprot/I6ZHX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_100020 ^@ http://purl.uniprot.org/uniprot/I6ZVQ0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/1178016:EROM_030950 ^@ http://purl.uniprot.org/uniprot/I6ZSZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_111280 ^@ http://purl.uniprot.org/uniprot/I7AQF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_021290 ^@ http://purl.uniprot.org/uniprot/I7ALQ6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/1178016:EROM_041200 ^@ http://purl.uniprot.org/uniprot/I6ZTB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/1178016:EROM_070040 ^@ http://purl.uniprot.org/uniprot/I7AF09 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/1178016:EROM_111170 ^@ http://purl.uniprot.org/uniprot/I6ZL94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Endomembrane system|||Vacuole membrane http://togogenome.org/gene/1178016:EROM_020720 ^@ http://purl.uniprot.org/uniprot/I7AQF7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/1178016:EROM_110360 ^@ http://purl.uniprot.org/uniprot/I6ZL19 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1178016:EROM_060470 ^@ http://purl.uniprot.org/uniprot/I6ZU26 ^@ Similarity ^@ Belongs to the TUB family. http://togogenome.org/gene/1178016:EROM_100410 ^@ http://purl.uniprot.org/uniprot/I7ATQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Membrane http://togogenome.org/gene/1178016:EROM_060540 ^@ http://purl.uniprot.org/uniprot/I6ZIY0 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/1178016:EROM_050460 ^@ http://purl.uniprot.org/uniprot/I7AMM8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/1178016:EROM_061070 ^@ http://purl.uniprot.org/uniprot/I7AN85 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/1178016:EROM_061400 ^@ http://purl.uniprot.org/uniprot/I6ZU95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_011260 ^@ http://purl.uniprot.org/uniprot/I7ACZ7 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/1178016:EROM_100480 ^@ http://purl.uniprot.org/uniprot/I7APR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/1178016:EROM_040340 ^@ http://purl.uniprot.org/uniprot/I6ZHW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/1178016:EROM_050010 ^@ http://purl.uniprot.org/uniprot/I7AE74 ^@ Similarity ^@ Belongs to the UPF0328 family. http://togogenome.org/gene/1178016:EROM_011200 ^@ http://purl.uniprot.org/uniprot/I7ALC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/1178016:EROM_030120 ^@ http://purl.uniprot.org/uniprot/I6ZSS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_081000 ^@ http://purl.uniprot.org/uniprot/I7AFK7 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/1178016:EROM_111290 ^@ http://purl.uniprot.org/uniprot/I7AH27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/1178016:EROM_110690 ^@ http://purl.uniprot.org/uniprot/I6ZWA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Nucleus|||Required both for recombination and for the repair of DNA damage caused by X-rays. http://togogenome.org/gene/1178016:EROM_070850 ^@ http://purl.uniprot.org/uniprot/I6ZUH6 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/1178016:EROM_101320 ^@ http://purl.uniprot.org/uniprot/I7ATY5 ^@ Similarity ^@ Belongs to the acetyltransferase family. GCN5 subfamily. http://togogenome.org/gene/1178016:EROM_010440 ^@ http://purl.uniprot.org/uniprot/I7AL62 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. http://togogenome.org/gene/1178016:EROM_030350 ^@ http://purl.uniprot.org/uniprot/I6ZSU9 ^@ Similarity ^@ Belongs to the sirtuin family. Class I subfamily. http://togogenome.org/gene/1178016:EROM_101020 ^@ http://purl.uniprot.org/uniprot/I7ATV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC2 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Component of the origin recognition complex (ORC).|||Nucleus http://togogenome.org/gene/1178016:EROM_061370 ^@ http://purl.uniprot.org/uniprot/I6ZJ36 ^@ Similarity ^@ Belongs to the NEMF family. http://togogenome.org/gene/1178016:EROM_111050 ^@ http://purl.uniprot.org/uniprot/I7AUC8 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1178016:EROM_040400 ^@ http://purl.uniprot.org/uniprot/I7AM91 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1178016:EROM_020830 ^@ http://purl.uniprot.org/uniprot/I6ZH84 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/1178016:EROM_060370 ^@ http://purl.uniprot.org/uniprot/I6ZU11 ^@ Similarity ^@ Belongs to the RNase Z family. http://togogenome.org/gene/1178016:EROM_080800 ^@ http://purl.uniprot.org/uniprot/I6ZJS1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/1178016:EROM_100510 ^@ http://purl.uniprot.org/uniprot/I7ATR0 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/1178016:EROM_021090 ^@ http://purl.uniprot.org/uniprot/I7ALN4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1178016:EROM_041330 ^@ http://purl.uniprot.org/uniprot/I7AMG7 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/1178016:EROM_101310 ^@ http://purl.uniprot.org/uniprot/I6ZW09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_030890 ^@ http://purl.uniprot.org/uniprot/I7ADQ7 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/1178016:EROM_110190 ^@ http://purl.uniprot.org/uniprot/I6ZL04 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1178016:EROM_050060 ^@ http://purl.uniprot.org/uniprot/I7AE77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Belongs to the small GTPase superfamily. SAR1 family.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane http://togogenome.org/gene/1178016:EROM_020880 ^@ http://purl.uniprot.org/uniprot/I6ZH89 ^@ Similarity ^@ Belongs to the TRAPP small subunits family. BET3 subfamily. http://togogenome.org/gene/1178016:EROM_020650 ^@ http://purl.uniprot.org/uniprot/I7AD63 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/1178016:EROM_030830 ^@ http://purl.uniprot.org/uniprot/I7AM15 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/1178016:EROM_030130 ^@ http://purl.uniprot.org/uniprot/I7AQR0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/1178016:EROM_010420 ^@ http://purl.uniprot.org/uniprot/I7AQ00 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/1178016:EROM_110110 ^@ http://purl.uniprot.org/uniprot/I7AGS9 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/1178016:EROM_080210 ^@ http://purl.uniprot.org/uniprot/I6ZJM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/1178016:EROM_041050 ^@ http://purl.uniprot.org/uniprot/I7AR84 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/1178016:EROM_071370 ^@ http://purl.uniprot.org/uniprot/I6ZJG9 ^@ Similarity ^@ Belongs to the dopey family. http://togogenome.org/gene/1178016:EROM_021380 ^@ http://purl.uniprot.org/uniprot/I6ZHD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/1178016:EROM_020690 ^@ http://purl.uniprot.org/uniprot/I7ALJ3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/1178016:EROM_110700 ^@ http://purl.uniprot.org/uniprot/I7AU94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus http://togogenome.org/gene/1178016:EROM_040530 ^@ http://purl.uniprot.org/uniprot/I6ZT68 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1178016:EROM_040560 ^@ http://purl.uniprot.org/uniprot/I7AMA4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/1178016:EROM_081950 ^@ http://purl.uniprot.org/uniprot/I7AP72 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1178016:EROM_100530 ^@ http://purl.uniprot.org/uniprot/I7APR4 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/1178016:EROM_070470 ^@ http://purl.uniprot.org/uniprot/I6ZJ88 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_080170 ^@ http://purl.uniprot.org/uniprot/I7ANS6 ^@ Similarity ^@ Belongs to the V-ATPase H subunit family. http://togogenome.org/gene/1178016:EROM_100450 ^@ http://purl.uniprot.org/uniprot/I6ZVT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/1178016:EROM_030480 ^@ http://purl.uniprot.org/uniprot/I7ALZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/1178016:EROM_071490 ^@ http://purl.uniprot.org/uniprot/I7AFC3 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_081130 ^@ http://purl.uniprot.org/uniprot/I7AP05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.|||Nucleus http://togogenome.org/gene/1178016:EROM_061470 ^@ http://purl.uniprot.org/uniprot/I6ZJ44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1178016:EROM_101340 ^@ http://purl.uniprot.org/uniprot/I7APZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/1178016:EROM_110840 ^@ http://purl.uniprot.org/uniprot/I6ZWC3 ^@ Similarity ^@ Belongs to the DCP1 family. http://togogenome.org/gene/1178016:EROM_070310 ^@ http://purl.uniprot.org/uniprot/I7AS86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Membrane http://togogenome.org/gene/1178016:EROM_081910 ^@ http://purl.uniprot.org/uniprot/I7AFT8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/1178016:EROM_041000 ^@ http://purl.uniprot.org/uniprot/I7AR80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Component of the T-complex protein 1 (TCP1) complex.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. http://togogenome.org/gene/1178016:EROM_101350 ^@ http://purl.uniprot.org/uniprot/I7AGP3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_110760 ^@ http://purl.uniprot.org/uniprot/I6ZL55 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1178016:EROM_010140 ^@ http://purl.uniprot.org/uniprot/I7AL33 ^@ Similarity ^@ Belongs to the BRX1 family. http://togogenome.org/gene/1178016:EROM_111630 ^@ http://purl.uniprot.org/uniprot/I7AQL5 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/1178016:EROM_100710 ^@ http://purl.uniprot.org/uniprot/I7ATS5 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/1178016:EROM_050130 ^@ http://purl.uniprot.org/uniprot/I6ZTG0 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family.