http://togogenome.org/gene/1449976:KALB_RS24730 ^@ http://purl.uniprot.org/uniprot/W5WC89 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS13625 ^@ http://purl.uniprot.org/uniprot/W5W5W2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1449976:KALB_RS39080 ^@ http://purl.uniprot.org/uniprot/W5WKB3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1449976:KALB_RS09700 ^@ http://purl.uniprot.org/uniprot/W5W4E3 ^@ Caution|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/1449976:KALB_RS16815 ^@ http://purl.uniprot.org/uniprot/W5WF23 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS38230 ^@ http://purl.uniprot.org/uniprot/W5WSM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS39985 ^@ http://purl.uniprot.org/uniprot/W5WKU8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS05900 ^@ http://purl.uniprot.org/uniprot/W5W154 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS24830 ^@ http://purl.uniprot.org/uniprot/W5WCA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS08245 ^@ http://purl.uniprot.org/uniprot/W5WA10 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS08460 ^@ http://purl.uniprot.org/uniprot/W5W2R3 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/1449976:KALB_RS39275 ^@ http://purl.uniprot.org/uniprot/W5WKF4 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1449976:KALB_RS35365 ^@ http://purl.uniprot.org/uniprot/W5WII4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1449976:KALB_RS40300 ^@ http://purl.uniprot.org/uniprot/W5WLB1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1449976:KALB_RS00525 ^@ http://purl.uniprot.org/uniprot/W5VYU9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS37440 ^@ http://purl.uniprot.org/uniprot/W5WK73 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1449976:KALB_RS41620 ^@ http://purl.uniprot.org/uniprot/W5WM13 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS30535 ^@ http://purl.uniprot.org/uniprot/W5WEF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42330 ^@ http://purl.uniprot.org/uniprot/W5WN28 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1449976:KALB_RS18420 ^@ http://purl.uniprot.org/uniprot/W5W821 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1449976:KALB_RS20075 ^@ http://purl.uniprot.org/uniprot/W5WA50 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS31315 ^@ http://purl.uniprot.org/uniprot/W5WFX1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS36305 ^@ http://purl.uniprot.org/uniprot/W5WRF8 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS05955 ^@ http://purl.uniprot.org/uniprot/W5W051 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS13705 ^@ http://purl.uniprot.org/uniprot/W5W6N4 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1449976:KALB_RS35540 ^@ http://purl.uniprot.org/uniprot/W5WIM4 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/1449976:KALB_RS02325 ^@ http://purl.uniprot.org/uniprot/W5VZ34 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/1449976:KALB_RS14735 ^@ http://purl.uniprot.org/uniprot/W5W6F4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1449976:KALB_RS36200 ^@ http://purl.uniprot.org/uniprot/W5WIQ5 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1449976:KALB_RS30955 ^@ http://purl.uniprot.org/uniprot/W5WND3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS41845 ^@ http://purl.uniprot.org/uniprot/W5WUN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1449976:KALB_RS08010 ^@ http://purl.uniprot.org/uniprot/W5W2A4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1449976:KALB_RS13315 ^@ http://purl.uniprot.org/uniprot/W5W584 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS34905 ^@ http://purl.uniprot.org/uniprot/W5WGY6 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1449976:KALB_RS44405 ^@ http://purl.uniprot.org/uniprot/W5WF51 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1449976:KALB_RS04140 ^@ http://purl.uniprot.org/uniprot/W5VZ72 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/1449976:KALB_RS16465 ^@ http://purl.uniprot.org/uniprot/W5W844 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/1449976:KALB_RS16270 ^@ http://purl.uniprot.org/uniprot/W5W702 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1449976:KALB_RS09555 ^@ http://purl.uniprot.org/uniprot/W5W4B3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1449976:KALB_RS44090 ^@ http://purl.uniprot.org/uniprot/W5W9P0 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/1449976:KALB_RS03615 ^@ http://purl.uniprot.org/uniprot/W5W7B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS05270 ^@ http://purl.uniprot.org/uniprot/W5W885 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1449976:KALB_RS37880 ^@ http://purl.uniprot.org/uniprot/W5WSC3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS31170 ^@ http://purl.uniprot.org/uniprot/W5WFV0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS38860 ^@ http://purl.uniprot.org/uniprot/W5WJ84 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1449976:KALB_RS09215 ^@ http://purl.uniprot.org/uniprot/W5W379 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1449976:KALB_RS08510 ^@ http://purl.uniprot.org/uniprot/W5W2S6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1449976:KALB_RS32640 ^@ http://purl.uniprot.org/uniprot/W5WFL8 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/1449976:KALB_RS15350 ^@ http://purl.uniprot.org/uniprot/W5W6S6 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/1449976:KALB_RS05330 ^@ http://purl.uniprot.org/uniprot/W5W0T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06540 ^@ http://purl.uniprot.org/uniprot/W5W1P8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS42810 ^@ http://purl.uniprot.org/uniprot/W5WV69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS32820 ^@ http://purl.uniprot.org/uniprot/W5WHF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS12425 ^@ http://purl.uniprot.org/uniprot/W5W3T3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS42525 ^@ http://purl.uniprot.org/uniprot/W5WMJ7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS37460 ^@ http://purl.uniprot.org/uniprot/W5WJQ8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS16675 ^@ http://purl.uniprot.org/uniprot/W5W880 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1449976:KALB_RS26825 ^@ http://purl.uniprot.org/uniprot/W5WD71 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS03565 ^@ http://purl.uniprot.org/uniprot/W5W7A4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1449976:KALB_RS16375 ^@ http://purl.uniprot.org/uniprot/W5W641 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS06295 ^@ http://purl.uniprot.org/uniprot/W5W2C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS01640 ^@ http://purl.uniprot.org/uniprot/W5VZ31 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1449976:KALB_RS34455 ^@ http://purl.uniprot.org/uniprot/W5WHM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS41365 ^@ http://purl.uniprot.org/uniprot/W5WLW3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS10810 ^@ http://purl.uniprot.org/uniprot/W5W2Z0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS35475 ^@ http://purl.uniprot.org/uniprot/W5WI99 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS14475 ^@ http://purl.uniprot.org/uniprot/W5W6A1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1449976:KALB_RS15045 ^@ http://purl.uniprot.org/uniprot/W5W659 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/1449976:KALB_RS13580 ^@ http://purl.uniprot.org/uniprot/W5W6I9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS10130 ^@ http://purl.uniprot.org/uniprot/W5W2L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS12185 ^@ http://purl.uniprot.org/uniprot/W5WC96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS37385 ^@ http://purl.uniprot.org/uniprot/W5WJP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1449976:KALB_RS18205 ^@ http://purl.uniprot.org/uniprot/W5W7A3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS22100 ^@ http://purl.uniprot.org/uniprot/W5WA81 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/1449976:KALB_RS41825 ^@ http://purl.uniprot.org/uniprot/W5WM53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1449976:KALB_RS34445 ^@ http://purl.uniprot.org/uniprot/W5WHZ2 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1449976:KALB_RS16945 ^@ http://purl.uniprot.org/uniprot/W5W7T4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS36285 ^@ http://purl.uniprot.org/uniprot/W5WJ34 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS32830 ^@ http://purl.uniprot.org/uniprot/W5WFQ8 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1449976:KALB_RS01705 ^@ http://purl.uniprot.org/uniprot/W5VXX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS05915 ^@ http://purl.uniprot.org/uniprot/W5W1A4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1449976:KALB_RS02280 ^@ http://purl.uniprot.org/uniprot/W5VY72 ^@ Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. http://togogenome.org/gene/1449976:KALB_RS06195 ^@ http://purl.uniprot.org/uniprot/W5W1D9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS31355 ^@ http://purl.uniprot.org/uniprot/W5WG68 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1449976:KALB_RS03360 ^@ http://purl.uniprot.org/uniprot/W5VYP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS22965 ^@ http://purl.uniprot.org/uniprot/W5WAP6 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS05850 ^@ http://purl.uniprot.org/uniprot/W5W146 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS18630 ^@ http://purl.uniprot.org/uniprot/W5W9D4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS44025 ^@ http://purl.uniprot.org/uniprot/W5W8D7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1449976:KALB_RS35660 ^@ http://purl.uniprot.org/uniprot/W5WR35 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1449976:KALB_RS43345 ^@ http://purl.uniprot.org/uniprot/W5WLU2 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/1449976:KALB_RS04800 ^@ http://purl.uniprot.org/uniprot/W5W0I8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS35600 ^@ http://purl.uniprot.org/uniprot/W5WIC7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS39235 ^@ http://purl.uniprot.org/uniprot/W5WT54 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1449976:KALB_RS03580 ^@ http://purl.uniprot.org/uniprot/W5VZU7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS16370 ^@ http://purl.uniprot.org/uniprot/W5W716 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS16185 ^@ http://purl.uniprot.org/uniprot/W5W7E7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40475 ^@ http://purl.uniprot.org/uniprot/W5WLE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS21085 ^@ http://purl.uniprot.org/uniprot/W5W959 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Vgb family.|||Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS00075 ^@ http://purl.uniprot.org/uniprot/W5VYK3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1449976:KALB_RS33650 ^@ http://purl.uniprot.org/uniprot/W5WI05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1449976:KALB_RS12005 ^@ http://purl.uniprot.org/uniprot/W5W4I6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/1449976:KALB_RS29150 ^@ http://purl.uniprot.org/uniprot/W5WEL7 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS16155 ^@ http://purl.uniprot.org/uniprot/W5WEQ8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1449976:KALB_RS15145 ^@ http://purl.uniprot.org/uniprot/W5W6M9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1449976:KALB_RS34320 ^@ http://purl.uniprot.org/uniprot/W5WQ87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS13945 ^@ http://purl.uniprot.org/uniprot/W5WDB9 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1449976:KALB_RS19680 ^@ http://purl.uniprot.org/uniprot/W5W9B1 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1449976:KALB_RS37230 ^@ http://purl.uniprot.org/uniprot/W5WRY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS33485 ^@ http://purl.uniprot.org/uniprot/W5WHX3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS15280 ^@ http://purl.uniprot.org/uniprot/W5W7C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS00450 ^@ http://purl.uniprot.org/uniprot/W5VYT3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS32040 ^@ http://purl.uniprot.org/uniprot/W5WF98 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS08055 ^@ http://purl.uniprot.org/uniprot/W5W3D6 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1449976:KALB_RS43240 ^@ http://purl.uniprot.org/uniprot/W5WMT4 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS16455 ^@ http://purl.uniprot.org/uniprot/W5WEV8 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS03855 ^@ http://purl.uniprot.org/uniprot/W5W026 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS17905 ^@ http://purl.uniprot.org/uniprot/W5W7R2 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/1449976:KALB_RS02330 ^@ http://purl.uniprot.org/uniprot/W5VY80 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS40755 ^@ http://purl.uniprot.org/uniprot/W5WLM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS14305 ^@ http://purl.uniprot.org/uniprot/W5W6W2 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1449976:KALB_RS28040 ^@ http://purl.uniprot.org/uniprot/W5WDZ1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS16650 ^@ http://purl.uniprot.org/uniprot/W5W875 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS15945 ^@ http://purl.uniprot.org/uniprot/W5W6Q7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS11190 ^@ http://purl.uniprot.org/uniprot/W5W382 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS07770 ^@ http://purl.uniprot.org/uniprot/W5W191 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1449976:KALB_RS09915 ^@ http://purl.uniprot.org/uniprot/W5WAY8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/1449976:KALB_RS11115 ^@ http://purl.uniprot.org/uniprot/W5W369 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS33620 ^@ http://purl.uniprot.org/uniprot/W5WHI5 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1449976:KALB_RS13655 ^@ http://purl.uniprot.org/uniprot/W5W6M8 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/1449976:KALB_RS27595 ^@ http://purl.uniprot.org/uniprot/W5WLC6 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1449976:KALB_RS34395 ^@ http://purl.uniprot.org/uniprot/W5WQA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS07925 ^@ http://purl.uniprot.org/uniprot/W5W2F6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1449976:KALB_RS41055 ^@ http://purl.uniprot.org/uniprot/W5WLR4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1449976:KALB_RS31785 ^@ http://purl.uniprot.org/uniprot/W5WG41 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1449976:KALB_RS04415 ^@ http://purl.uniprot.org/uniprot/W5W0B2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS18085 ^@ http://purl.uniprot.org/uniprot/W5W8D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS28175 ^@ http://purl.uniprot.org/uniprot/W5WER8 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS15710 ^@ http://purl.uniprot.org/uniprot/W5W7K8 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS14370 ^@ http://purl.uniprot.org/uniprot/W5WDJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS49090 ^@ http://purl.uniprot.org/uniprot/W5W2I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS26785 ^@ http://purl.uniprot.org/uniprot/W5WCC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13305 ^@ http://purl.uniprot.org/uniprot/W5W5K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS18715 ^@ http://purl.uniprot.org/uniprot/W5W7P5 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1449976:KALB_RS17345 ^@ http://purl.uniprot.org/uniprot/W5W6P2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS23585 ^@ http://purl.uniprot.org/uniprot/W5WAL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42870 ^@ http://purl.uniprot.org/uniprot/W5WND7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1449976:KALB_RS27160 ^@ http://purl.uniprot.org/uniprot/W5WL42 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS40210 ^@ http://purl.uniprot.org/uniprot/W5WL11 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1449976:KALB_RS27105 ^@ http://purl.uniprot.org/uniprot/W5WDC9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS34540 ^@ http://purl.uniprot.org/uniprot/W5WQD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS01805 ^@ http://purl.uniprot.org/uniprot/W5VYU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS30810 ^@ http://purl.uniprot.org/uniprot/W5WNA7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS00630 ^@ http://purl.uniprot.org/uniprot/W5VY58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS16925 ^@ http://purl.uniprot.org/uniprot/W5W8C4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS36845 ^@ http://purl.uniprot.org/uniprot/W5WRP8 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS40550 ^@ http://purl.uniprot.org/uniprot/W5WM37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1449976:KALB_RS36350 ^@ http://purl.uniprot.org/uniprot/W5WHT5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1449976:KALB_RS36730 ^@ http://purl.uniprot.org/uniprot/W5WJT2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1449976:KALB_RS49180 ^@ http://purl.uniprot.org/uniprot/W5W7D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS00010 ^@ http://purl.uniprot.org/uniprot/W5W598 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1449976:KALB_RS01050 ^@ http://purl.uniprot.org/uniprot/W5VXK9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS43455 ^@ http://purl.uniprot.org/uniprot/W5WN48 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1449976:KALB_RS35960 ^@ http://purl.uniprot.org/uniprot/W5WR95 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1449976:KALB_RS35695 ^@ http://purl.uniprot.org/uniprot/W5WJ88 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/1449976:KALB_RS02645 ^@ http://purl.uniprot.org/uniprot/W5W025 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS25565 ^@ http://purl.uniprot.org/uniprot/W5WBJ9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1449976:KALB_RS05795 ^@ http://purl.uniprot.org/uniprot/W5W177 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS38005 ^@ http://purl.uniprot.org/uniprot/W5WSF1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS37960 ^@ http://purl.uniprot.org/uniprot/W5WK06 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1449976:KALB_RS34340 ^@ http://purl.uniprot.org/uniprot/W5WGM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS25650 ^@ http://purl.uniprot.org/uniprot/W5WDA3 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS39210 ^@ http://purl.uniprot.org/uniprot/W5WT48 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS34315 ^@ http://purl.uniprot.org/uniprot/W5WGL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Cell membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/1449976:KALB_RS34265 ^@ http://purl.uniprot.org/uniprot/W5WGK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS30925 ^@ http://purl.uniprot.org/uniprot/W5WEP0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS20150 ^@ http://purl.uniprot.org/uniprot/W5W8H6 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1449976:KALB_RS00845 ^@ http://purl.uniprot.org/uniprot/W5VYM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS37270 ^@ http://purl.uniprot.org/uniprot/W5WJ86 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS20710 ^@ http://purl.uniprot.org/uniprot/W5W9B7 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1449976:KALB_RS35925 ^@ http://purl.uniprot.org/uniprot/W5WIL3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1449976:KALB_RS33455 ^@ http://purl.uniprot.org/uniprot/W5WHF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/1449976:KALB_RS02890 ^@ http://purl.uniprot.org/uniprot/W5VZN1 ^@ Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS03925 ^@ http://purl.uniprot.org/uniprot/W5W0X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1449976:KALB_RS01650 ^@ http://purl.uniprot.org/uniprot/W5VYS3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1449976:KALB_RS16055 ^@ http://purl.uniprot.org/uniprot/W5WEK3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS09785 ^@ http://purl.uniprot.org/uniprot/W5W2E9 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/1449976:KALB_RS12645 ^@ http://purl.uniprot.org/uniprot/W5W4V7 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/1449976:KALB_RS41490 ^@ http://purl.uniprot.org/uniprot/W5WKR1 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1449976:KALB_RS19860 ^@ http://purl.uniprot.org/uniprot/W5W8V6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS34950 ^@ http://purl.uniprot.org/uniprot/W5WGZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS15205 ^@ http://purl.uniprot.org/uniprot/W5W696 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS15720 ^@ http://purl.uniprot.org/uniprot/W5W5N5 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1449976:KALB_RS39565 ^@ http://purl.uniprot.org/uniprot/W5WKW2 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1449976:KALB_RS15080 ^@ http://purl.uniprot.org/uniprot/W5WE06 ^@ Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. http://togogenome.org/gene/1449976:KALB_RS36345 ^@ http://purl.uniprot.org/uniprot/W5WIS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1449976:KALB_RS03065 ^@ http://purl.uniprot.org/uniprot/W5VZR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1449976:KALB_RS09580 ^@ http://purl.uniprot.org/uniprot/W5W4B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1449976:KALB_RS32735 ^@ http://purl.uniprot.org/uniprot/W5WFN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS22390 ^@ http://purl.uniprot.org/uniprot/W5WAV1 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS21550 ^@ http://purl.uniprot.org/uniprot/W5W9Y5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS35895 ^@ http://purl.uniprot.org/uniprot/W5WJC8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS33850 ^@ http://purl.uniprot.org/uniprot/W5WHC4 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS37375 ^@ http://purl.uniprot.org/uniprot/W5WIE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1449976:KALB_RS39445 ^@ http://purl.uniprot.org/uniprot/W5WLD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42255 ^@ http://purl.uniprot.org/uniprot/W5WN14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/1449976:KALB_RS41425 ^@ http://purl.uniprot.org/uniprot/W5WLP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS11380 ^@ http://purl.uniprot.org/uniprot/W5W4I4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS34605 ^@ http://purl.uniprot.org/uniprot/W5WGS7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS14150 ^@ http://purl.uniprot.org/uniprot/W5W642 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1449976:KALB_RS35905 ^@ http://purl.uniprot.org/uniprot/W5WHK6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1449976:KALB_RS38495 ^@ http://purl.uniprot.org/uniprot/W5WSS2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS03420 ^@ http://purl.uniprot.org/uniprot/W5VZX5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1449976:KALB_RS43320 ^@ http://purl.uniprot.org/uniprot/W5WLT7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1449976:KALB_RS29975 ^@ http://purl.uniprot.org/uniprot/W5WFT1 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/1449976:KALB_RS31180 ^@ http://purl.uniprot.org/uniprot/W5WNH6 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS12475 ^@ http://purl.uniprot.org/uniprot/W5W3U2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS10250 ^@ http://purl.uniprot.org/uniprot/W5W3N6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS14055 ^@ http://purl.uniprot.org/uniprot/W5W6T2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS42555 ^@ http://purl.uniprot.org/uniprot/W5WN66 ^@ Caution|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS14225 ^@ http://purl.uniprot.org/uniprot/W5W655 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS37940 ^@ http://purl.uniprot.org/uniprot/W5WKI2 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/1449976:KALB_RS32855 ^@ http://purl.uniprot.org/uniprot/W5WFR2 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1449976:KALB_RS07895 ^@ http://purl.uniprot.org/uniprot/W5W9T9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1449976:KALB_RS38485 ^@ http://purl.uniprot.org/uniprot/W5WK21 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS32475 ^@ http://purl.uniprot.org/uniprot/W5WGU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1449976:KALB_RS10700 ^@ http://purl.uniprot.org/uniprot/W5W4Z9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS17595 ^@ http://purl.uniprot.org/uniprot/W5W6V2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS03245 ^@ http://purl.uniprot.org/uniprot/W5VZU3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS24900 ^@ http://purl.uniprot.org/uniprot/W5WJS0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/1449976:KALB_RS15170 ^@ http://purl.uniprot.org/uniprot/W5W6N6 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the IcmF family.|||Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.|||Heterodimer of an alpha and a beta chain.|||Homodimer.|||Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS07380 ^@ http://purl.uniprot.org/uniprot/W5W2Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS42795 ^@ http://purl.uniprot.org/uniprot/W5WNC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS41605 ^@ http://purl.uniprot.org/uniprot/W5WLS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS28195 ^@ http://purl.uniprot.org/uniprot/W5WEA3 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1449976:KALB_RS19245 ^@ http://purl.uniprot.org/uniprot/W5W9N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS30110 ^@ http://purl.uniprot.org/uniprot/W5WE72 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS34720 ^@ http://purl.uniprot.org/uniprot/W5WHT2 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1449976:KALB_RS18220 ^@ http://purl.uniprot.org/uniprot/W5W903 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1449976:KALB_RS03935 ^@ http://purl.uniprot.org/uniprot/W5VZ37 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS03405 ^@ http://purl.uniprot.org/uniprot/W5VZQ1 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/1449976:KALB_RS42110 ^@ http://purl.uniprot.org/uniprot/W5WM20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1449976:KALB_RS00240 ^@ http://purl.uniprot.org/uniprot/W5W5D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS39340 ^@ http://purl.uniprot.org/uniprot/W5WKR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS32495 ^@ http://purl.uniprot.org/uniprot/W5WP61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1449976:KALB_RS02750 ^@ http://purl.uniprot.org/uniprot/W5VZB8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1449976:KALB_RS04525 ^@ http://purl.uniprot.org/uniprot/W5W0I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS29080 ^@ http://purl.uniprot.org/uniprot/W5WDM4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS04445 ^@ http://purl.uniprot.org/uniprot/W5VZC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1449976:KALB_RS40170 ^@ http://purl.uniprot.org/uniprot/W5WTP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily.|||Periplasm http://togogenome.org/gene/1449976:KALB_RS28960 ^@ http://purl.uniprot.org/uniprot/W5WM63 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS43025 ^@ http://purl.uniprot.org/uniprot/W5WVC0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS18435 ^@ http://purl.uniprot.org/uniprot/W5W8L4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1449976:KALB_RS16470 ^@ http://purl.uniprot.org/uniprot/W5W732 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1449976:KALB_RS29890 ^@ http://purl.uniprot.org/uniprot/W5WFB3 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS03240 ^@ http://purl.uniprot.org/uniprot/W5W730 ^@ Function|||Similarity|||Subunit ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS07450 ^@ http://purl.uniprot.org/uniprot/W5W2Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS39560 ^@ http://purl.uniprot.org/uniprot/W5WTC2 ^@ Function|||Similarity ^@ Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.|||In the C-terminal section; belongs to the radical SAM superfamily. CofH family.|||In the N-terminal section; belongs to the radical SAM superfamily. CofG family. http://togogenome.org/gene/1449976:KALB_RS16065 ^@ http://purl.uniprot.org/uniprot/W5W7T6 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1449976:KALB_RS42645 ^@ http://purl.uniprot.org/uniprot/W5WMC7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1449976:KALB_RS35100 ^@ http://purl.uniprot.org/uniprot/W5WIS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1449976:KALB_RS03560 ^@ http://purl.uniprot.org/uniprot/W5VYT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1449976:KALB_RS09455 ^@ http://purl.uniprot.org/uniprot/W5W498 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS39010 ^@ http://purl.uniprot.org/uniprot/W5WT08 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS15705 ^@ http://purl.uniprot.org/uniprot/W5W701 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS11465 ^@ http://purl.uniprot.org/uniprot/W5W4C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS40340 ^@ http://purl.uniprot.org/uniprot/W5WK32 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1449976:KALB_RS13710 ^@ http://purl.uniprot.org/uniprot/W5W5J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS12770 ^@ http://purl.uniprot.org/uniprot/W5W4X9 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1449976:KALB_RS23130 ^@ http://purl.uniprot.org/uniprot/W5WIQ1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS32590 ^@ http://purl.uniprot.org/uniprot/W5WFL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS42025 ^@ http://purl.uniprot.org/uniprot/W5WM90 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1449976:KALB_RS36545 ^@ http://purl.uniprot.org/uniprot/W5WRJ2 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1449976:KALB_RS10830 ^@ http://purl.uniprot.org/uniprot/W5W3Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08320 ^@ http://purl.uniprot.org/uniprot/W5W3K3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1449976:KALB_RS42765 ^@ http://purl.uniprot.org/uniprot/W5WMP2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40925 ^@ http://purl.uniprot.org/uniprot/W5WU69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS40745 ^@ http://purl.uniprot.org/uniprot/W5WKC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS11400 ^@ http://purl.uniprot.org/uniprot/W5WBV4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS18625 ^@ http://purl.uniprot.org/uniprot/W5W8U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS35730 ^@ http://purl.uniprot.org/uniprot/W5WHH7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1449976:KALB_RS17600 ^@ http://purl.uniprot.org/uniprot/W5WFH1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS40890 ^@ http://purl.uniprot.org/uniprot/W5WLH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1449976:KALB_RS40065 ^@ http://purl.uniprot.org/uniprot/W5WJX3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS15330 ^@ http://purl.uniprot.org/uniprot/W5W7D3 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS05310 ^@ http://purl.uniprot.org/uniprot/W5W0S8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS36340 ^@ http://purl.uniprot.org/uniprot/W5WJL4 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1449976:KALB_RS21655 ^@ http://purl.uniprot.org/uniprot/W5W9F7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS19280 ^@ http://purl.uniprot.org/uniprot/W5W7Z2 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1449976:KALB_RS43090 ^@ http://purl.uniprot.org/uniprot/W5WMM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS33010 ^@ http://purl.uniprot.org/uniprot/W5WPG3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/1449976:KALB_RS08240 ^@ http://purl.uniprot.org/uniprot/W5W1H0 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/1449976:KALB_RS43650 ^@ http://purl.uniprot.org/uniprot/W5W8H8 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS08265 ^@ http://purl.uniprot.org/uniprot/W5W1H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS03060 ^@ http://purl.uniprot.org/uniprot/W5W6Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1449976:KALB_RS27295 ^@ http://purl.uniprot.org/uniprot/W5WDR8 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1449976:KALB_RS32350 ^@ http://purl.uniprot.org/uniprot/W5WGR4 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS15475 ^@ http://purl.uniprot.org/uniprot/W5W5H3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS10785 ^@ http://purl.uniprot.org/uniprot/W5W2Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13855 ^@ http://purl.uniprot.org/uniprot/W5W6Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS01195 ^@ http://purl.uniprot.org/uniprot/W5VYU0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS01695 ^@ http://purl.uniprot.org/uniprot/W5VZL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1449976:KALB_RS19785 ^@ http://purl.uniprot.org/uniprot/W5W9Z8 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/1449976:KALB_RS27290 ^@ http://purl.uniprot.org/uniprot/W5WL67 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/1449976:KALB_RS14860 ^@ http://purl.uniprot.org/uniprot/W5W6H7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS23010 ^@ http://purl.uniprot.org/uniprot/W5WAQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS06660 ^@ http://purl.uniprot.org/uniprot/W5W1R5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1449976:KALB_RS20470 ^@ http://purl.uniprot.org/uniprot/W5W9R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS27030 ^@ http://purl.uniprot.org/uniprot/W5WDB1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS09390 ^@ http://purl.uniprot.org/uniprot/W5W288 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS09590 ^@ http://purl.uniprot.org/uniprot/W5W2B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1449976:KALB_RS25320 ^@ http://purl.uniprot.org/uniprot/W5WJZ3 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS10510 ^@ http://purl.uniprot.org/uniprot/W5W2T3 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1449976:KALB_RS36595 ^@ http://purl.uniprot.org/uniprot/W5WRK0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1449976:KALB_RS32745 ^@ http://purl.uniprot.org/uniprot/W5WGZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS34715 ^@ http://purl.uniprot.org/uniprot/W5WIK8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1449976:KALB_RS28315 ^@ http://purl.uniprot.org/uniprot/W5WLW1 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1449976:KALB_RS22290 ^@ http://purl.uniprot.org/uniprot/W5WAT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40050 ^@ http://purl.uniprot.org/uniprot/W5WL64 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1449976:KALB_RS32865 ^@ http://purl.uniprot.org/uniprot/W5WH19 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS42520 ^@ http://purl.uniprot.org/uniprot/W5WV14 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS17465 ^@ http://purl.uniprot.org/uniprot/W5W7H7 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1449976:KALB_RS34880 ^@ http://purl.uniprot.org/uniprot/W5WGY1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1449976:KALB_RS32125 ^@ http://purl.uniprot.org/uniprot/W5WH25 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS19990 ^@ http://purl.uniprot.org/uniprot/W5WGW4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS33380 ^@ http://purl.uniprot.org/uniprot/W5WHF1 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/1449976:KALB_RS08735 ^@ http://purl.uniprot.org/uniprot/W5WAE6 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1449976:KALB_RS13635 ^@ http://purl.uniprot.org/uniprot/W5W5H6 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1449976:KALB_RS05650 ^@ http://purl.uniprot.org/uniprot/W5VZZ6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1449976:KALB_RS28920 ^@ http://purl.uniprot.org/uniprot/W5WF92 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS17895 ^@ http://purl.uniprot.org/uniprot/W5W895 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. PqqE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).|||Interacts with PqqD. The interaction is necessary for activity of PqqE. http://togogenome.org/gene/1449976:KALB_RS33760 ^@ http://purl.uniprot.org/uniprot/W5WGB0 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/1449976:KALB_RS14245 ^@ http://purl.uniprot.org/uniprot/W5WDH7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS14945 ^@ http://purl.uniprot.org/uniprot/W5W636 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1449976:KALB_RS00605 ^@ http://purl.uniprot.org/uniprot/W5VY53 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS13330 ^@ http://purl.uniprot.org/uniprot/W5W5K8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS02350 ^@ http://purl.uniprot.org/uniprot/W5VZ38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS04210 ^@ http://purl.uniprot.org/uniprot/W5VZ84 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1449976:KALB_RS10520 ^@ http://purl.uniprot.org/uniprot/W5W3Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS06880 ^@ http://purl.uniprot.org/uniprot/W5W998 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1449976:KALB_RS04045 ^@ http://purl.uniprot.org/uniprot/W5W7K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS07645 ^@ http://purl.uniprot.org/uniprot/W5W290 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS46500 ^@ http://purl.uniprot.org/uniprot/W5W5T5 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/1449976:KALB_RS27890 ^@ http://purl.uniprot.org/uniprot/W5WEK7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS37820 ^@ http://purl.uniprot.org/uniprot/W5WKF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS02670 ^@ http://purl.uniprot.org/uniprot/W5W029 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS30520 ^@ http://purl.uniprot.org/uniprot/W5WFN9 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS04535 ^@ http://purl.uniprot.org/uniprot/W5W0D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS03645 ^@ http://purl.uniprot.org/uniprot/W5W016 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1449976:KALB_RS38260 ^@ http://purl.uniprot.org/uniprot/W5WSM8 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1449976:KALB_RS37355 ^@ http://purl.uniprot.org/uniprot/W5WS12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36175 ^@ http://purl.uniprot.org/uniprot/W5WIQ2 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1449976:KALB_RS39700 ^@ http://purl.uniprot.org/uniprot/W5WKN9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS16625 ^@ http://purl.uniprot.org/uniprot/W5WEY5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS13735 ^@ http://purl.uniprot.org/uniprot/W5W5J5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1449976:KALB_RS43350 ^@ http://purl.uniprot.org/uniprot/W5WVL3 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS44910 ^@ http://purl.uniprot.org/uniprot/W5WDC7 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1449976:KALB_RS22090 ^@ http://purl.uniprot.org/uniprot/W5WAQ2 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1449976:KALB_RS11525 ^@ http://purl.uniprot.org/uniprot/W5W5H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1449976:KALB_RS29015 ^@ http://purl.uniprot.org/uniprot/W5WES8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS24710 ^@ http://purl.uniprot.org/uniprot/W5WBV0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1449976:KALB_RS33025 ^@ http://purl.uniprot.org/uniprot/W5WGU8 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1449976:KALB_RS26985 ^@ http://purl.uniprot.org/uniprot/W5WCH0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS33715 ^@ http://purl.uniprot.org/uniprot/W5WPX9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS01945 ^@ http://purl.uniprot.org/uniprot/W5VZ78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS38360 ^@ http://purl.uniprot.org/uniprot/W5WKU9 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/1449976:KALB_RS15275 ^@ http://purl.uniprot.org/uniprot/W5W6Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS10750 ^@ http://purl.uniprot.org/uniprot/W5W509 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS14335 ^@ http://purl.uniprot.org/uniprot/W5W5T8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1449976:KALB_RS21095 ^@ http://purl.uniprot.org/uniprot/W5WA86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS09070 ^@ http://purl.uniprot.org/uniprot/W5W2Z1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS05370 ^@ http://purl.uniprot.org/uniprot/W5W0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40710 ^@ http://purl.uniprot.org/uniprot/W5WM97 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS32370 ^@ http://purl.uniprot.org/uniprot/W5WP42 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1449976:KALB_RS38795 ^@ http://purl.uniprot.org/uniprot/W5WKG2 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1449976:KALB_RS30860 ^@ http://purl.uniprot.org/uniprot/W5WFZ6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS12895 ^@ http://purl.uniprot.org/uniprot/W5W5C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36185 ^@ http://purl.uniprot.org/uniprot/W5WRD6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1449976:KALB_RS43505 ^@ http://purl.uniprot.org/uniprot/W5WN56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1449976:KALB_RS32060 ^@ http://purl.uniprot.org/uniprot/W5WG91 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS05470 ^@ http://purl.uniprot.org/uniprot/W5W8C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS26780 ^@ http://purl.uniprot.org/uniprot/W5WD62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13435 ^@ http://purl.uniprot.org/uniprot/W5W6F5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS05210 ^@ http://purl.uniprot.org/uniprot/W5W0R3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1449976:KALB_RS17525 ^@ http://purl.uniprot.org/uniprot/W5WFF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS38865 ^@ http://purl.uniprot.org/uniprot/W5WSY0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1449976:KALB_RS34760 ^@ http://purl.uniprot.org/uniprot/W5WQH9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS19385 ^@ http://purl.uniprot.org/uniprot/W5WGJ1 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1449976:KALB_RS35315 ^@ http://purl.uniprot.org/uniprot/W5WIH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1449976:KALB_RS20755 ^@ http://purl.uniprot.org/uniprot/W5W8U2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS38515 ^@ http://purl.uniprot.org/uniprot/W5WJ28 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1449976:KALB_RS34690 ^@ http://purl.uniprot.org/uniprot/W5WIK1 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.|||Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine. http://togogenome.org/gene/1449976:KALB_RS02555 ^@ http://purl.uniprot.org/uniprot/W5VYB4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/1449976:KALB_RS40290 ^@ http://purl.uniprot.org/uniprot/W5WK22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1449976:KALB_RS41980 ^@ http://purl.uniprot.org/uniprot/W5WMW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS11435 ^@ http://purl.uniprot.org/uniprot/W5W5G4 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1449976:KALB_RS21330 ^@ http://purl.uniprot.org/uniprot/W5W9A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS34870 ^@ http://purl.uniprot.org/uniprot/W5WIN6 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1449976:KALB_RS00715 ^@ http://purl.uniprot.org/uniprot/W5W5P1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12210 ^@ http://purl.uniprot.org/uniprot/W5WCA1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1449976:KALB_RS24705 ^@ http://purl.uniprot.org/uniprot/W5WCT6 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS12430 ^@ http://purl.uniprot.org/uniprot/W5WCE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS05605 ^@ http://purl.uniprot.org/uniprot/W5W8E9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS06965 ^@ http://purl.uniprot.org/uniprot/W5W2Q6 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS18815 ^@ http://purl.uniprot.org/uniprot/W5W8E1 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/1449976:KALB_RS20110 ^@ http://purl.uniprot.org/uniprot/W5W8G5 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1449976:KALB_RS38600 ^@ http://purl.uniprot.org/uniprot/W5WKD0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1449976:KALB_RS31995 ^@ http://purl.uniprot.org/uniprot/W5WNX2 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1449976:KALB_RS27480 ^@ http://purl.uniprot.org/uniprot/W5WDW1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1449976:KALB_RS04050 ^@ http://purl.uniprot.org/uniprot/W5W098 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS39505 ^@ http://purl.uniprot.org/uniprot/W5WJL5 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1449976:KALB_RS09490 ^@ http://purl.uniprot.org/uniprot/W5W2A1 ^@ Similarity ^@ Belongs to the peptidase S45 family. http://togogenome.org/gene/1449976:KALB_RS08295 ^@ http://purl.uniprot.org/uniprot/W5W2M9 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/1449976:KALB_RS40810 ^@ http://purl.uniprot.org/uniprot/W5WMB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS24715 ^@ http://purl.uniprot.org/uniprot/W5WB49 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1449976:KALB_RS47060 ^@ http://purl.uniprot.org/uniprot/W5WNK2 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1449976:KALB_RS02050 ^@ http://purl.uniprot.org/uniprot/W5VZS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS09105 ^@ http://purl.uniprot.org/uniprot/W5WAK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40795 ^@ http://purl.uniprot.org/uniprot/W5WKD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS48525 ^@ http://purl.uniprot.org/uniprot/W5W807 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS20625 ^@ http://purl.uniprot.org/uniprot/W5W9V2 ^@ Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. http://togogenome.org/gene/1449976:KALB_RS42565 ^@ http://purl.uniprot.org/uniprot/W5WLB3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1449976:KALB_RS29570 ^@ http://purl.uniprot.org/uniprot/W5WFK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS37350 ^@ http://purl.uniprot.org/uniprot/W5WID7 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1449976:KALB_RS48040 ^@ http://purl.uniprot.org/uniprot/W5WKN7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS02795 ^@ http://purl.uniprot.org/uniprot/W5W046 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS05885 ^@ http://purl.uniprot.org/uniprot/W5W8L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS11295 ^@ http://purl.uniprot.org/uniprot/W5WBU2 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS10325 ^@ http://purl.uniprot.org/uniprot/W5W4R4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS29515 ^@ http://purl.uniprot.org/uniprot/W5WF31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS27070 ^@ http://purl.uniprot.org/uniprot/W5WDM2 ^@ Function|||Subunit ^@ Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1449976:KALB_RS39845 ^@ http://purl.uniprot.org/uniprot/W5WJT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1449976:KALB_RS01475 ^@ http://purl.uniprot.org/uniprot/W5VZH6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS15660 ^@ http://purl.uniprot.org/uniprot/W5W7J6 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS42615 ^@ http://purl.uniprot.org/uniprot/W5WN73 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS15995 ^@ http://purl.uniprot.org/uniprot/W5W6R9 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS41955 ^@ http://purl.uniprot.org/uniprot/W5WMW0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1449976:KALB_RS40450 ^@ http://purl.uniprot.org/uniprot/W5WLD8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1449976:KALB_RS06670 ^@ http://purl.uniprot.org/uniprot/W5W1L8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS33965 ^@ http://purl.uniprot.org/uniprot/W5WHP4 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1449976:KALB_RS18650 ^@ http://purl.uniprot.org/uniprot/W5W8U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS10635 ^@ http://purl.uniprot.org/uniprot/W5W2V4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS10525 ^@ http://purl.uniprot.org/uniprot/W5W4V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS10435 ^@ http://purl.uniprot.org/uniprot/W5W3S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS28760 ^@ http://purl.uniprot.org/uniprot/W5WM32 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS00785 ^@ http://purl.uniprot.org/uniprot/W5VXG2 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1449976:KALB_RS40365 ^@ http://purl.uniprot.org/uniprot/W5WK37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1449976:KALB_RS07780 ^@ http://purl.uniprot.org/uniprot/W5W2C9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1449976:KALB_RS04515 ^@ http://purl.uniprot.org/uniprot/W5VZD6 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1449976:KALB_RS41660 ^@ http://purl.uniprot.org/uniprot/W5WKU6 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS09410 ^@ http://purl.uniprot.org/uniprot/W5W350 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS08845 ^@ http://purl.uniprot.org/uniprot/W5W2V6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protease inhibitor I16 (SSI) family.|||Homodimer.|||Secreted http://togogenome.org/gene/1449976:KALB_RS17620 ^@ http://purl.uniprot.org/uniprot/W5W6V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40760 ^@ http://purl.uniprot.org/uniprot/W5WMA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS32890 ^@ http://purl.uniprot.org/uniprot/W5WH22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06935 ^@ http://purl.uniprot.org/uniprot/W5W1V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1449976:KALB_RS38555 ^@ http://purl.uniprot.org/uniprot/W5WKY5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1449976:KALB_RS45925 ^@ http://purl.uniprot.org/uniprot/W5WGE0 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS37790 ^@ http://purl.uniprot.org/uniprot/W5WJX2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS02510 ^@ http://purl.uniprot.org/uniprot/W5W6P0 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1449976:KALB_RS18770 ^@ http://purl.uniprot.org/uniprot/W5WG79 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1449976:KALB_RS06550 ^@ http://purl.uniprot.org/uniprot/W5W1K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS31580 ^@ http://purl.uniprot.org/uniprot/W5WG09 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1449976:KALB_RS43635 ^@ http://purl.uniprot.org/uniprot/W5W1D4 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/1449976:KALB_RS34755 ^@ http://purl.uniprot.org/uniprot/W5WGV6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS27705 ^@ http://purl.uniprot.org/uniprot/W5WE10 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS38200 ^@ http://purl.uniprot.org/uniprot/W5WIX7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS37080 ^@ http://purl.uniprot.org/uniprot/W5WI86 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS02820 ^@ http://purl.uniprot.org/uniprot/W5W049 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1449976:KALB_RS22645 ^@ http://purl.uniprot.org/uniprot/W5WAH4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1449976:KALB_RS36480 ^@ http://purl.uniprot.org/uniprot/W5WJN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS27000 ^@ http://purl.uniprot.org/uniprot/W5WE45 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS30410 ^@ http://purl.uniprot.org/uniprot/W5WFC5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS04145 ^@ http://purl.uniprot.org/uniprot/W5W7L6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. PqqE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).|||Interacts with PqqD. The interaction is necessary for activity of PqqE. http://togogenome.org/gene/1449976:KALB_RS06730 ^@ http://purl.uniprot.org/uniprot/W5W0P9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS14665 ^@ http://purl.uniprot.org/uniprot/W5W6E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1449976:KALB_RS15375 ^@ http://purl.uniprot.org/uniprot/W5WE66 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS13990 ^@ http://purl.uniprot.org/uniprot/W5W4N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS39160 ^@ http://purl.uniprot.org/uniprot/W5WT38 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1449976:KALB_RS30295 ^@ http://purl.uniprot.org/uniprot/W5WMX1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1449976:KALB_RS23760 ^@ http://purl.uniprot.org/uniprot/W5WBF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40200 ^@ http://purl.uniprot.org/uniprot/W5WL97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1449976:KALB_RS21770 ^@ http://purl.uniprot.org/uniprot/W5WB68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS28740 ^@ http://purl.uniprot.org/uniprot/W5WEN0 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1449976:KALB_RS38410 ^@ http://purl.uniprot.org/uniprot/W5WKV8 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS01260 ^@ http://purl.uniprot.org/uniprot/W5W639 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS06430 ^@ http://purl.uniprot.org/uniprot/W5W926 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS24670 ^@ http://purl.uniprot.org/uniprot/W5WJM6 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS18955 ^@ http://purl.uniprot.org/uniprot/W5W9J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1449976:KALB_RS14615 ^@ http://purl.uniprot.org/uniprot/W5W6D0 ^@ Function ^@ Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/1449976:KALB_RS29310 ^@ http://purl.uniprot.org/uniprot/W5WEY4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS39895 ^@ http://purl.uniprot.org/uniprot/W5WJU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS15090 ^@ http://purl.uniprot.org/uniprot/W5W798 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1449976:KALB_RS29630 ^@ http://purl.uniprot.org/uniprot/W5WDY3 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/1449976:KALB_RS02945 ^@ http://purl.uniprot.org/uniprot/W5W071 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS15805 ^@ http://purl.uniprot.org/uniprot/W5WEF0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1449976:KALB_RS13865 ^@ http://purl.uniprot.org/uniprot/W5W4M0 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS44570 ^@ http://purl.uniprot.org/uniprot/W5WQR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbxX/CfxQ family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS17680 ^@ http://purl.uniprot.org/uniprot/W5W8R3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1449976:KALB_RS10045 ^@ http://purl.uniprot.org/uniprot/W5W4K5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS42440 ^@ http://purl.uniprot.org/uniprot/W5WL91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36230 ^@ http://purl.uniprot.org/uniprot/W5WRE5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS07455 ^@ http://purl.uniprot.org/uniprot/W5W1Z7 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/1449976:KALB_RS02675 ^@ http://purl.uniprot.org/uniprot/W5VZA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS38840 ^@ http://purl.uniprot.org/uniprot/W5WSX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36220 ^@ http://purl.uniprot.org/uniprot/W5WIQ9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1449976:KALB_RS01990 ^@ http://purl.uniprot.org/uniprot/W5W6G4 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1449976:KALB_RS36475 ^@ http://purl.uniprot.org/uniprot/W5WJ64 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1449976:KALB_RS35465 ^@ http://purl.uniprot.org/uniprot/W5WIK6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1449976:KALB_RS25195 ^@ http://purl.uniprot.org/uniprot/W5WJW8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS07920 ^@ http://purl.uniprot.org/uniprot/W5W9U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1449976:KALB_RS40370 ^@ http://purl.uniprot.org/uniprot/W5WTT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS34130 ^@ http://purl.uniprot.org/uniprot/W5WHS1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/1449976:KALB_RS36055 ^@ http://purl.uniprot.org/uniprot/W5WHN5 ^@ Similarity ^@ Belongs to the PhoU family. http://togogenome.org/gene/1449976:KALB_RS38275 ^@ http://purl.uniprot.org/uniprot/W5WJY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1449976:KALB_RS38125 ^@ http://purl.uniprot.org/uniprot/W5WIT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS35515 ^@ http://purl.uniprot.org/uniprot/W5WIL9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS17070 ^@ http://purl.uniprot.org/uniprot/W5W7V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1449976:KALB_RS18820 ^@ http://purl.uniprot.org/uniprot/W5W7R3 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1449976:KALB_RS15795 ^@ http://purl.uniprot.org/uniprot/W5W6M1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS26375 ^@ http://purl.uniprot.org/uniprot/W5WC35 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS29855 ^@ http://purl.uniprot.org/uniprot/W5WE28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1449976:KALB_RS00625 ^@ http://purl.uniprot.org/uniprot/W5VYW6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS39545 ^@ http://purl.uniprot.org/uniprot/W5WLG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS19085 ^@ http://purl.uniprot.org/uniprot/W5WGD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS02460 ^@ http://purl.uniprot.org/uniprot/W5W6N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS12175 ^@ http://purl.uniprot.org/uniprot/W5W4L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12465 ^@ http://purl.uniprot.org/uniprot/W5W5X0 ^@ Similarity ^@ Belongs to the PhoU family. http://togogenome.org/gene/1449976:KALB_RS08180 ^@ http://purl.uniprot.org/uniprot/W5W3G4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS14490 ^@ http://purl.uniprot.org/uniprot/W5WDM5 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1449976:KALB_RS01180 ^@ http://purl.uniprot.org/uniprot/W5VXM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12360 ^@ http://purl.uniprot.org/uniprot/W5W526 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13925 ^@ http://purl.uniprot.org/uniprot/W5W607 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS31725 ^@ http://purl.uniprot.org/uniprot/W5WNS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS19375 ^@ http://purl.uniprot.org/uniprot/W5W8N7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS16525 ^@ http://purl.uniprot.org/uniprot/W5WEX1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1449976:KALB_RS35835 ^@ http://purl.uniprot.org/uniprot/W5WR73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1449976:KALB_RS04570 ^@ http://purl.uniprot.org/uniprot/W5W7U9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS19690 ^@ http://purl.uniprot.org/uniprot/W5W8T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS40100 ^@ http://purl.uniprot.org/uniprot/W5WL74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1449976:KALB_RS48880 ^@ http://purl.uniprot.org/uniprot/W5WPV3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS36120 ^@ http://purl.uniprot.org/uniprot/W5WJH4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1449976:KALB_RS04490 ^@ http://purl.uniprot.org/uniprot/W5W0C4 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1449976:KALB_RS38520 ^@ http://purl.uniprot.org/uniprot/W5WSS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS37480 ^@ http://purl.uniprot.org/uniprot/W5WS38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS07775 ^@ http://purl.uniprot.org/uniprot/W5W9R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1449976:KALB_RS35700 ^@ http://purl.uniprot.org/uniprot/W5WIH4 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1449976:KALB_RS40350 ^@ http://purl.uniprot.org/uniprot/W5WLC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1449976:KALB_RS16920 ^@ http://purl.uniprot.org/uniprot/W5W7S9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS05540 ^@ http://purl.uniprot.org/uniprot/W5W1R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1449976:KALB_RS34310 ^@ http://purl.uniprot.org/uniprot/W5WHJ9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1449976:KALB_RS05400 ^@ http://purl.uniprot.org/uniprot/W5VZV7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1449976:KALB_RS36510 ^@ http://purl.uniprot.org/uniprot/W5WIV2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1449976:KALB_RS21060 ^@ http://purl.uniprot.org/uniprot/W5W954 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1449976:KALB_RS40120 ^@ http://purl.uniprot.org/uniprot/W5WTN2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1449976:KALB_RS04820 ^@ http://purl.uniprot.org/uniprot/W5W1D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS08300 ^@ http://purl.uniprot.org/uniprot/W5W3J7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS16315 ^@ http://purl.uniprot.org/uniprot/W5W818 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS08825 ^@ http://purl.uniprot.org/uniprot/W5W1Y6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07730 ^@ http://purl.uniprot.org/uniprot/W5W256 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS32300 ^@ http://purl.uniprot.org/uniprot/W5WGQ4 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1449976:KALB_RS33660 ^@ http://purl.uniprot.org/uniprot/W5WG94 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS35555 ^@ http://purl.uniprot.org/uniprot/W5WHC2 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS09485 ^@ http://purl.uniprot.org/uniprot/W5W366 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS07185 ^@ http://purl.uniprot.org/uniprot/W5W1U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06145 ^@ http://purl.uniprot.org/uniprot/W5W1B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1449976:KALB_RS30685 ^@ http://purl.uniprot.org/uniprot/W5WEI4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS15830 ^@ http://purl.uniprot.org/uniprot/W5WEF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS39595 ^@ http://purl.uniprot.org/uniprot/W5WLH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06235 ^@ http://purl.uniprot.org/uniprot/W5W1J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS12280 ^@ http://purl.uniprot.org/uniprot/W5WCB7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS33170 ^@ http://purl.uniprot.org/uniprot/W5WHM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS15885 ^@ http://purl.uniprot.org/uniprot/W5W747 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS00880 ^@ http://purl.uniprot.org/uniprot/W5VYA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12490 ^@ http://purl.uniprot.org/uniprot/W5W5X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS31800 ^@ http://purl.uniprot.org/uniprot/W5WGE8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1449976:KALB_RS21285 ^@ http://purl.uniprot.org/uniprot/W5WHP7 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1449976:KALB_RS02595 ^@ http://purl.uniprot.org/uniprot/W5W017 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1449976:KALB_RS40390 ^@ http://purl.uniprot.org/uniprot/W5WK42 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS14925 ^@ http://purl.uniprot.org/uniprot/W5W581 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS07790 ^@ http://purl.uniprot.org/uniprot/W5W266 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1449976:KALB_RS06760 ^@ http://purl.uniprot.org/uniprot/W5W979 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/1449976:KALB_RS36870 ^@ http://purl.uniprot.org/uniprot/W5WJD8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/1449976:KALB_RS04400 ^@ http://purl.uniprot.org/uniprot/W5W7R6 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS35870 ^@ http://purl.uniprot.org/uniprot/W5WJC2 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1449976:KALB_RS02125 ^@ http://purl.uniprot.org/uniprot/W5VZT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS13470 ^@ http://purl.uniprot.org/uniprot/W5WCZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS26275 ^@ http://purl.uniprot.org/uniprot/W5WD80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1449976:KALB_RS37775 ^@ http://purl.uniprot.org/uniprot/W5WJJ4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS26770 ^@ http://purl.uniprot.org/uniprot/W5WDG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS25180 ^@ http://purl.uniprot.org/uniprot/W5WD19 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS18490 ^@ http://purl.uniprot.org/uniprot/W5W957 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS03570 ^@ http://purl.uniprot.org/uniprot/W5W001 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1449976:KALB_RS35770 ^@ http://purl.uniprot.org/uniprot/W5WJA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS04650 ^@ http://purl.uniprot.org/uniprot/W5W1A2 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS17040 ^@ http://purl.uniprot.org/uniprot/W5WF66 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS02660 ^@ http://purl.uniprot.org/uniprot/W5W6R8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/1449976:KALB_RS34440 ^@ http://purl.uniprot.org/uniprot/W5WGP2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS33720 ^@ http://purl.uniprot.org/uniprot/W5WHK1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1449976:KALB_RS00755 ^@ http://purl.uniprot.org/uniprot/W5VY83 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/1449976:KALB_RS38090 ^@ http://purl.uniprot.org/uniprot/W5WKL8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1449976:KALB_RS40335 ^@ http://purl.uniprot.org/uniprot/W5WL39 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS43095 ^@ http://purl.uniprot.org/uniprot/W5WLL5 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/1449976:KALB_RS07285 ^@ http://purl.uniprot.org/uniprot/W5W0Z2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS40945 ^@ http://purl.uniprot.org/uniprot/W5WKG1 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/1449976:KALB_RS20535 ^@ http://purl.uniprot.org/uniprot/W5W8Q7 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1449976:KALB_RS28775 ^@ http://purl.uniprot.org/uniprot/W5WEF6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS08865 ^@ http://purl.uniprot.org/uniprot/W5W401 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1449976:KALB_RS22870 ^@ http://purl.uniprot.org/uniprot/W5WA34 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1449976:KALB_RS20245 ^@ http://purl.uniprot.org/uniprot/W5W924 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS38700 ^@ http://purl.uniprot.org/uniprot/W5WKE4 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1449976:KALB_RS13875 ^@ http://purl.uniprot.org/uniprot/W5W5Z9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS39140 ^@ http://purl.uniprot.org/uniprot/W5WT33 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/1449976:KALB_RS13285 ^@ http://purl.uniprot.org/uniprot/W5W6C0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS39225 ^@ http://purl.uniprot.org/uniprot/W5WKE5 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS29370 ^@ http://purl.uniprot.org/uniprot/W5WDS8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1449976:KALB_RS02285 ^@ http://purl.uniprot.org/uniprot/W5W6K7 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS34940 ^@ http://purl.uniprot.org/uniprot/W5WIQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS25130 ^@ http://purl.uniprot.org/uniprot/W5WD10 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS36140 ^@ http://purl.uniprot.org/uniprot/W5WJ08 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/1449976:KALB_RS14035 ^@ http://purl.uniprot.org/uniprot/W5W5P2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1449976:KALB_RS34770 ^@ http://purl.uniprot.org/uniprot/W5WIL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS36145 ^@ http://purl.uniprot.org/uniprot/W5WJH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1449976:KALB_RS40280 ^@ http://purl.uniprot.org/uniprot/W5WLW6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1449976:KALB_RS02515 ^@ http://purl.uniprot.org/uniprot/W5VZG8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS01155 ^@ http://purl.uniprot.org/uniprot/W5VXM3 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1449976:KALB_RS40555 ^@ http://purl.uniprot.org/uniprot/W5WL88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1449976:KALB_RS14060 ^@ http://purl.uniprot.org/uniprot/W5W5P6 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS28285 ^@ http://purl.uniprot.org/uniprot/W5WD81 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/1449976:KALB_RS43690 ^@ http://purl.uniprot.org/uniprot/W5W0Q7 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS35860 ^@ http://purl.uniprot.org/uniprot/W5WR78 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1449976:KALB_RS09340 ^@ http://purl.uniprot.org/uniprot/W5W3A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS30615 ^@ http://purl.uniprot.org/uniprot/W5WN33 ^@ Function|||Subunit ^@ Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1449976:KALB_RS09640 ^@ http://purl.uniprot.org/uniprot/W5W2C4 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1449976:KALB_RS37170 ^@ http://purl.uniprot.org/uniprot/W5WK18 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1449976:KALB_RS36700 ^@ http://purl.uniprot.org/uniprot/W5WJA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1449976:KALB_RS38815 ^@ http://purl.uniprot.org/uniprot/W5WSX1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1449976:KALB_RS40090 ^@ http://purl.uniprot.org/uniprot/W5WJX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS28595 ^@ http://purl.uniprot.org/uniprot/W5WEL0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS40270 ^@ http://purl.uniprot.org/uniprot/W5WTR3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS08325 ^@ http://purl.uniprot.org/uniprot/W5W2G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS32965 ^@ http://purl.uniprot.org/uniprot/W5WH38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS37105 ^@ http://purl.uniprot.org/uniprot/W5WI91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS29585 ^@ http://purl.uniprot.org/uniprot/W5WMI0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS21000 ^@ http://purl.uniprot.org/uniprot/W5WAR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1449976:KALB_RS30325 ^@ http://purl.uniprot.org/uniprot/W5WFK3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS33360 ^@ http://purl.uniprot.org/uniprot/W5WHV1 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS08005 ^@ http://purl.uniprot.org/uniprot/W5W3C3 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1449976:KALB_RS36915 ^@ http://purl.uniprot.org/uniprot/W5WRR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS25395 ^@ http://purl.uniprot.org/uniprot/W5WCN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS38300 ^@ http://purl.uniprot.org/uniprot/W5WJY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS04200 ^@ http://purl.uniprot.org/uniprot/W5W117 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS05085 ^@ http://purl.uniprot.org/uniprot/W5W0P2 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1449976:KALB_RS19035 ^@ http://purl.uniprot.org/uniprot/W5WGC4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS25505 ^@ http://purl.uniprot.org/uniprot/W5WD72 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1449976:KALB_RS15005 ^@ http://purl.uniprot.org/uniprot/W5WDY6 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1449976:KALB_RS42100 ^@ http://purl.uniprot.org/uniprot/W5WMA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1449976:KALB_RS20660 ^@ http://purl.uniprot.org/uniprot/W5W9A9 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1449976:KALB_RS00175 ^@ http://purl.uniprot.org/uniprot/W5VYM2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1449976:KALB_RS02790 ^@ http://purl.uniprot.org/uniprot/W5VZL4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS01810 ^@ http://purl.uniprot.org/uniprot/W5VXY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1449976:KALB_RS29885 ^@ http://purl.uniprot.org/uniprot/W5WMN9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1449976:KALB_RS14835 ^@ http://purl.uniprot.org/uniprot/W5W6H1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1449976:KALB_RS00035 ^@ http://purl.uniprot.org/uniprot/W5W5A1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1449976:KALB_RS19790 ^@ http://purl.uniprot.org/uniprot/W5W896 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS40275 ^@ http://purl.uniprot.org/uniprot/W5WLA7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1449976:KALB_RS29730 ^@ http://purl.uniprot.org/uniprot/W5WE05 ^@ Similarity ^@ Belongs to the EccD/Snm4 family. http://togogenome.org/gene/1449976:KALB_RS16365 ^@ http://purl.uniprot.org/uniprot/W5W826 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS01370 ^@ http://purl.uniprot.org/uniprot/W5VZF7 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1449976:KALB_RS31125 ^@ http://purl.uniprot.org/uniprot/W5WER9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1449976:KALB_RS12290 ^@ http://purl.uniprot.org/uniprot/W5W5U3 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1449976:KALB_RS32330 ^@ http://purl.uniprot.org/uniprot/W5WH62 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1449976:KALB_RS19005 ^@ http://purl.uniprot.org/uniprot/W5W9J9 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS38735 ^@ http://purl.uniprot.org/uniprot/W5WK59 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/1449976:KALB_RS26410 ^@ http://purl.uniprot.org/uniprot/W5WKN6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1449976:KALB_RS04470 ^@ http://purl.uniprot.org/uniprot/W5VZC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1449976:KALB_RS10390 ^@ http://purl.uniprot.org/uniprot/W5WB83 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28A subfamily. http://togogenome.org/gene/1449976:KALB_RS18080 ^@ http://purl.uniprot.org/uniprot/W5WFR3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS12260 ^@ http://purl.uniprot.org/uniprot/W5W507 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08705 ^@ http://purl.uniprot.org/uniprot/W5W1W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS15870 ^@ http://purl.uniprot.org/uniprot/W5W6N5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS31795 ^@ http://purl.uniprot.org/uniprot/W5WNT3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1449976:KALB_RS36295 ^@ http://purl.uniprot.org/uniprot/W5WIS3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS27230 ^@ http://purl.uniprot.org/uniprot/W5WDF7 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1449976:KALB_RS41090 ^@ http://purl.uniprot.org/uniprot/W5WKI9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS39400 ^@ http://purl.uniprot.org/uniprot/W5WKI0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1449976:KALB_RS24635 ^@ http://purl.uniprot.org/uniprot/W5WBU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS38405 ^@ http://purl.uniprot.org/uniprot/W5WKA1 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS01220 ^@ http://purl.uniprot.org/uniprot/W5VZB5 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1449976:KALB_RS20070 ^@ http://purl.uniprot.org/uniprot/W5W9I4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS06085 ^@ http://purl.uniprot.org/uniprot/W5W8Q6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1449976:KALB_RS30795 ^@ http://purl.uniprot.org/uniprot/W5WGC8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS04295 ^@ http://purl.uniprot.org/uniprot/W5W0D4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS36240 ^@ http://purl.uniprot.org/uniprot/W5WJJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1449976:KALB_RS02605 ^@ http://purl.uniprot.org/uniprot/W5VYC4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/1449976:KALB_RS37015 ^@ http://purl.uniprot.org/uniprot/W5WJG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS17960 ^@ http://purl.uniprot.org/uniprot/W5W8A7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS13785 ^@ http://purl.uniprot.org/uniprot/W5W5K2 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1449976:KALB_RS12710 ^@ http://purl.uniprot.org/uniprot/W5W591 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/1449976:KALB_RS38110 ^@ http://purl.uniprot.org/uniprot/W5WK36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06370 ^@ http://purl.uniprot.org/uniprot/W5W1G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1449976:KALB_RS07810 ^@ http://purl.uniprot.org/uniprot/W5W270 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS22455 ^@ http://purl.uniprot.org/uniprot/W5WIC2 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40045 ^@ http://purl.uniprot.org/uniprot/W5WTL7 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/1449976:KALB_RS03895 ^@ http://purl.uniprot.org/uniprot/W5W077 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1449976:KALB_RS25680 ^@ http://purl.uniprot.org/uniprot/W5WBL8 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS08260 ^@ http://purl.uniprot.org/uniprot/W5W2F1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1449976:KALB_RS08900 ^@ http://purl.uniprot.org/uniprot/W5W200 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS41290 ^@ http://purl.uniprot.org/uniprot/W5WUD0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS43190 ^@ http://purl.uniprot.org/uniprot/W5WMS7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS34190 ^@ http://purl.uniprot.org/uniprot/W5WGJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS09810 ^@ http://purl.uniprot.org/uniprot/W5W2F3 ^@ Caution|||Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS19530 ^@ http://purl.uniprot.org/uniprot/W5W986 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/1449976:KALB_RS39585 ^@ http://purl.uniprot.org/uniprot/W5WTC9 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1449976:KALB_RS13880 ^@ http://purl.uniprot.org/uniprot/W5W6R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1449976:KALB_RS26875 ^@ http://purl.uniprot.org/uniprot/W5WE26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS20265 ^@ http://purl.uniprot.org/uniprot/W5WA84 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS07010 ^@ http://purl.uniprot.org/uniprot/W5W1W9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS29090 ^@ http://purl.uniprot.org/uniprot/W5WEU5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS43415 ^@ http://purl.uniprot.org/uniprot/W5WMW4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1449976:KALB_RS36775 ^@ http://purl.uniprot.org/uniprot/W5WJB9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/1449976:KALB_RS43445 ^@ http://purl.uniprot.org/uniprot/W5WLV7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1449976:KALB_RS20350 ^@ http://purl.uniprot.org/uniprot/W5WAA1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS04900 ^@ http://purl.uniprot.org/uniprot/W5W814 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS33115 ^@ http://purl.uniprot.org/uniprot/W5WH70 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1449976:KALB_RS33125 ^@ http://purl.uniprot.org/uniprot/W5WGW8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS40220 ^@ http://purl.uniprot.org/uniprot/W5WTQ2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1449976:KALB_RS08355 ^@ http://purl.uniprot.org/uniprot/W5WA36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS09840 ^@ http://purl.uniprot.org/uniprot/W5WAX5 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1449976:KALB_RS34705 ^@ http://purl.uniprot.org/uniprot/W5WQG8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1449976:KALB_RS32335 ^@ http://purl.uniprot.org/uniprot/W5WGE3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1449976:KALB_RS40870 ^@ http://purl.uniprot.org/uniprot/W5WKE7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS08380 ^@ http://purl.uniprot.org/uniprot/W5WA40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS35385 ^@ http://purl.uniprot.org/uniprot/W5WQV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1449976:KALB_RS21945 ^@ http://purl.uniprot.org/uniprot/W5WBA0 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS40400 ^@ http://purl.uniprot.org/uniprot/W5WLC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1449976:KALB_RS06610 ^@ http://purl.uniprot.org/uniprot/W5W951 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS13270 ^@ http://purl.uniprot.org/uniprot/W5W483 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS22630 ^@ http://purl.uniprot.org/uniprot/W5WIF3 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1449976:KALB_RS05940 ^@ http://purl.uniprot.org/uniprot/W5W1A8 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Has an organic peroxide-dependent peroxidase activity. http://togogenome.org/gene/1449976:KALB_RS13700 ^@ http://purl.uniprot.org/uniprot/W5W5X5 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1449976:KALB_RS33080 ^@ http://purl.uniprot.org/uniprot/W5WFV8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1449976:KALB_RS01110 ^@ http://purl.uniprot.org/uniprot/W5VYS4 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1449976:KALB_RS41050 ^@ http://purl.uniprot.org/uniprot/W5WU88 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1449976:KALB_RS42175 ^@ http://purl.uniprot.org/uniprot/W5WMC1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS24330 ^@ http://purl.uniprot.org/uniprot/W5WBP2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1449976:KALB_RS04395 ^@ http://purl.uniprot.org/uniprot/W5VZB4 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/1449976:KALB_RS33280 ^@ http://purl.uniprot.org/uniprot/W5WG27 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS02010 ^@ http://purl.uniprot.org/uniprot/W5VY24 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1449976:KALB_RS30195 ^@ http://purl.uniprot.org/uniprot/W5WFH8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS41180 ^@ http://purl.uniprot.org/uniprot/W5WLL2 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1449976:KALB_RS37315 ^@ http://purl.uniprot.org/uniprot/W5WK49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS08160 ^@ http://purl.uniprot.org/uniprot/W5W2D4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1449976:KALB_RS40770 ^@ http://purl.uniprot.org/uniprot/W5WKD1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS23815 ^@ http://purl.uniprot.org/uniprot/W5WAP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS03915 ^@ http://purl.uniprot.org/uniprot/W5W7I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1449976:KALB_RS42095 ^@ http://purl.uniprot.org/uniprot/W5WUT1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/1449976:KALB_RS38845 ^@ http://purl.uniprot.org/uniprot/W5WKH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07205 ^@ http://purl.uniprot.org/uniprot/W5W2V3 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1449976:KALB_RS28045 ^@ http://purl.uniprot.org/uniprot/W5WD09 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS38280 ^@ http://purl.uniprot.org/uniprot/W5WIY9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1449976:KALB_RS40190 ^@ http://purl.uniprot.org/uniprot/W5WK00 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1449976:KALB_RS30855 ^@ http://purl.uniprot.org/uniprot/W5WNB6 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1449976:KALB_RS17350 ^@ http://purl.uniprot.org/uniprot/W5WFC3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS34480 ^@ http://purl.uniprot.org/uniprot/W5WHN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13870 ^@ http://purl.uniprot.org/uniprot/W5WDA4 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS10205 ^@ http://purl.uniprot.org/uniprot/W5W2N2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS10560 ^@ http://purl.uniprot.org/uniprot/W5W2U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS29565 ^@ http://purl.uniprot.org/uniprot/W5WF43 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS09735 ^@ http://purl.uniprot.org/uniprot/W5W2E1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1449976:KALB_RS16480 ^@ http://purl.uniprot.org/uniprot/W5WEW3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS13695 ^@ http://purl.uniprot.org/uniprot/W5WD74 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS22340 ^@ http://purl.uniprot.org/uniprot/W5WAU4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1449976:KALB_RS24805 ^@ http://purl.uniprot.org/uniprot/W5WCA4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1449976:KALB_RS15410 ^@ http://purl.uniprot.org/uniprot/W5W7E5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS01530 ^@ http://purl.uniprot.org/uniprot/W5VXU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS02345 ^@ http://purl.uniprot.org/uniprot/W5VZY0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1449976:KALB_RS07825 ^@ http://purl.uniprot.org/uniprot/W5W2D7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1449976:KALB_RS31490 ^@ http://purl.uniprot.org/uniprot/W5WNN1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS10210 ^@ http://purl.uniprot.org/uniprot/W5WB52 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS01780 ^@ http://purl.uniprot.org/uniprot/W5VYU6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1449976:KALB_RS01585 ^@ http://purl.uniprot.org/uniprot/W5W694 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1449976:KALB_RS02580 ^@ http://purl.uniprot.org/uniprot/W5VYB9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1449976:KALB_RS38685 ^@ http://purl.uniprot.org/uniprot/W5WK50 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS41695 ^@ http://purl.uniprot.org/uniprot/W5WM27 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS19810 ^@ http://purl.uniprot.org/uniprot/W5W8U8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS08315 ^@ http://purl.uniprot.org/uniprot/W5W2N4 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1449976:KALB_RS17735 ^@ http://purl.uniprot.org/uniprot/W5W7M5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS13360 ^@ http://purl.uniprot.org/uniprot/W5W5L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS05960 ^@ http://purl.uniprot.org/uniprot/W5W8N1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS01690 ^@ http://purl.uniprot.org/uniprot/W5VZ40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/1449976:KALB_RS29560 ^@ http://purl.uniprot.org/uniprot/W5WMH6 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS02680 ^@ http://purl.uniprot.org/uniprot/W5VYD6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1449976:KALB_RS07190 ^@ http://purl.uniprot.org/uniprot/W5W0X4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS10905 ^@ http://purl.uniprot.org/uniprot/W5W410 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS38715 ^@ http://purl.uniprot.org/uniprot/W5WJ61 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.|||Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides. http://togogenome.org/gene/1449976:KALB_RS38980 ^@ http://purl.uniprot.org/uniprot/W5WK99 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS03620 ^@ http://purl.uniprot.org/uniprot/W5W011 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS38665 ^@ http://purl.uniprot.org/uniprot/W5WJ52 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS43080 ^@ http://purl.uniprot.org/uniprot/W5WMW1 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1449976:KALB_RS27935 ^@ http://purl.uniprot.org/uniprot/W5WEL4 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1449976:KALB_RS38350 ^@ http://purl.uniprot.org/uniprot/W5WSP8 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1449976:KALB_RS34520 ^@ http://purl.uniprot.org/uniprot/W5WI08 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1449976:KALB_RS29860 ^@ http://purl.uniprot.org/uniprot/W5WMN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS29420 ^@ http://purl.uniprot.org/uniprot/W5WME7 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1449976:KALB_RS34100 ^@ http://purl.uniprot.org/uniprot/W5WQ41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS34580 ^@ http://purl.uniprot.org/uniprot/W5WGS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1449976:KALB_RS16490 ^@ http://purl.uniprot.org/uniprot/W5W849 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/1449976:KALB_RS30470 ^@ http://purl.uniprot.org/uniprot/W5WN03 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS19845 ^@ http://purl.uniprot.org/uniprot/W5WGT3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS15345 ^@ http://purl.uniprot.org/uniprot/W5WE60 ^@ Function|||Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate. http://togogenome.org/gene/1449976:KALB_RS26290 ^@ http://purl.uniprot.org/uniprot/W5WC22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1449976:KALB_RS15015 ^@ http://purl.uniprot.org/uniprot/W5W784 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS10320 ^@ http://purl.uniprot.org/uniprot/W5W3U8 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1449976:KALB_RS07575 ^@ http://purl.uniprot.org/uniprot/W5W325 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1449976:KALB_RS08305 ^@ http://purl.uniprot.org/uniprot/W5W1I3 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/1449976:KALB_RS26425 ^@ http://purl.uniprot.org/uniprot/W5WD04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS07935 ^@ http://purl.uniprot.org/uniprot/W5W292 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS13675 ^@ http://purl.uniprot.org/uniprot/W5W5X1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS26890 ^@ http://purl.uniprot.org/uniprot/W5WKY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS14170 ^@ http://purl.uniprot.org/uniprot/W5WDG3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1449976:KALB_RS00005 ^@ http://purl.uniprot.org/uniprot/W5VX16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1449976:KALB_RS34035 ^@ http://purl.uniprot.org/uniprot/W5WQ28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS40655 ^@ http://purl.uniprot.org/uniprot/W5WU21 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1449976:KALB_RS32455 ^@ http://purl.uniprot.org/uniprot/W5WH86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1449976:KALB_RS27055 ^@ http://purl.uniprot.org/uniprot/W5WDB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS15305 ^@ http://purl.uniprot.org/uniprot/W5W7D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS14830 ^@ http://purl.uniprot.org/uniprot/W5WDU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS32425 ^@ http://purl.uniprot.org/uniprot/W5WGT0 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1449976:KALB_RS01340 ^@ http://purl.uniprot.org/uniprot/W5VYY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS28975 ^@ http://purl.uniprot.org/uniprot/W5WEI8 ^@ Similarity ^@ Belongs to the clavaminate synthase family. http://togogenome.org/gene/1449976:KALB_RS09745 ^@ http://purl.uniprot.org/uniprot/W5W3J4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/1449976:KALB_RS34915 ^@ http://purl.uniprot.org/uniprot/W5WI87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1449976:KALB_RS14175 ^@ http://purl.uniprot.org/uniprot/W5W646 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS14235 ^@ http://purl.uniprot.org/uniprot/W5W5S5 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1449976:KALB_RS28820 ^@ http://purl.uniprot.org/uniprot/W5WF74 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS02500 ^@ http://purl.uniprot.org/uniprot/W5VZ70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS19850 ^@ http://purl.uniprot.org/uniprot/W5W9E1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS05520 ^@ http://purl.uniprot.org/uniprot/W5W0W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS16430 ^@ http://purl.uniprot.org/uniprot/W5WEV4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1449976:KALB_RS16585 ^@ http://purl.uniprot.org/uniprot/W5W865 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS30585 ^@ http://purl.uniprot.org/uniprot/W5WEG4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS09550 ^@ http://purl.uniprot.org/uniprot/W5W3F3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS35845 ^@ http://purl.uniprot.org/uniprot/W5WJB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS41775 ^@ http://purl.uniprot.org/uniprot/W5WM44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1449976:KALB_RS30275 ^@ http://purl.uniprot.org/uniprot/W5WFJ2 ^@ Similarity ^@ Belongs to the clavaminate synthase family. http://togogenome.org/gene/1449976:KALB_RS34855 ^@ http://purl.uniprot.org/uniprot/W5WGX7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS40430 ^@ http://purl.uniprot.org/uniprot/W5WM01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS23270 ^@ http://purl.uniprot.org/uniprot/W5WAA7 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS40160 ^@ http://purl.uniprot.org/uniprot/W5WL01 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS21735 ^@ http://purl.uniprot.org/uniprot/W5WHX9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS42570 ^@ http://purl.uniprot.org/uniprot/W5WV25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1449976:KALB_RS24860 ^@ http://purl.uniprot.org/uniprot/W5WCW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS35480 ^@ http://purl.uniprot.org/uniprot/W5WHA8 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1449976:KALB_RS01090 ^@ http://purl.uniprot.org/uniprot/W5VZ71 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS29825 ^@ http://purl.uniprot.org/uniprot/W5WF02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS38765 ^@ http://purl.uniprot.org/uniprot/W5WSW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1449976:KALB_RS22125 ^@ http://purl.uniprot.org/uniprot/W5WA83 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/1449976:KALB_RS30665 ^@ http://purl.uniprot.org/uniprot/W5WN43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07580 ^@ http://purl.uniprot.org/uniprot/W5W226 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1449976:KALB_RS14965 ^@ http://purl.uniprot.org/uniprot/W5W776 ^@ Function|||Similarity ^@ Belongs to the LuxC family.|||LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase. http://togogenome.org/gene/1449976:KALB_RS32460 ^@ http://purl.uniprot.org/uniprot/W5WGH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1449976:KALB_RS35525 ^@ http://purl.uniprot.org/uniprot/W5WIB1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS22670 ^@ http://purl.uniprot.org/uniprot/W5W9Z7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS32285 ^@ http://purl.uniprot.org/uniprot/W5WGD2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS08650 ^@ http://purl.uniprot.org/uniprot/W5W2S2 ^@ Similarity ^@ Belongs to the clavaminate synthase family. http://togogenome.org/gene/1449976:KALB_RS26570 ^@ http://purl.uniprot.org/uniprot/W5WC76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12785 ^@ http://purl.uniprot.org/uniprot/W5W5A4 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1449976:KALB_RS08065 ^@ http://purl.uniprot.org/uniprot/W5W1E6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1449976:KALB_RS16495 ^@ http://purl.uniprot.org/uniprot/W5W734 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS37195 ^@ http://purl.uniprot.org/uniprot/W5WK23 ^@ Function|||Subcellular Location Annotation ^@ Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS02475 ^@ http://purl.uniprot.org/uniprot/W5VZ66 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1449976:KALB_RS04015 ^@ http://purl.uniprot.org/uniprot/W5VZ51 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1449976:KALB_RS35750 ^@ http://purl.uniprot.org/uniprot/W5WII3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40600 ^@ http://purl.uniprot.org/uniprot/W5WLI4 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/1449976:KALB_RS13195 ^@ http://purl.uniprot.org/uniprot/W5W465 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS06215 ^@ http://purl.uniprot.org/uniprot/W5W2B4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1449976:KALB_RS03040 ^@ http://purl.uniprot.org/uniprot/W5VZQ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1449976:KALB_RS16630 ^@ http://purl.uniprot.org/uniprot/W5W872 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS32160 ^@ http://purl.uniprot.org/uniprot/W5WFC6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1449976:KALB_RS00250 ^@ http://purl.uniprot.org/uniprot/W5VYN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS31640 ^@ http://purl.uniprot.org/uniprot/W5WNQ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS36085 ^@ http://purl.uniprot.org/uniprot/W5WRB9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1449976:KALB_RS18345 ^@ http://purl.uniprot.org/uniprot/W5W805 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS35840 ^@ http://purl.uniprot.org/uniprot/W5WIW1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS02300 ^@ http://purl.uniprot.org/uniprot/W5VZ29 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS00220 ^@ http://purl.uniprot.org/uniprot/W5VYA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS21795 ^@ http://purl.uniprot.org/uniprot/W5WB72 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS05550 ^@ http://purl.uniprot.org/uniprot/W5VZY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1449976:KALB_RS24535 ^@ http://purl.uniprot.org/uniprot/W5WCR0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/1449976:KALB_RS02630 ^@ http://purl.uniprot.org/uniprot/W5VYC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1449976:KALB_RS21270 ^@ http://purl.uniprot.org/uniprot/W5WAZ3 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/1449976:KALB_RS17485 ^@ http://purl.uniprot.org/uniprot/W5W8M7 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1449976:KALB_RS00740 ^@ http://purl.uniprot.org/uniprot/W5W5P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS05415 ^@ http://purl.uniprot.org/uniprot/W5W1N8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1449976:KALB_RS43315 ^@ http://purl.uniprot.org/uniprot/W5WMU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1449976:KALB_RS36995 ^@ http://purl.uniprot.org/uniprot/W5WJY0 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1449976:KALB_RS30380 ^@ http://purl.uniprot.org/uniprot/W5WG01 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS23315 ^@ http://purl.uniprot.org/uniprot/W5WAY1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS20705 ^@ http://purl.uniprot.org/uniprot/W5WAH1 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1449976:KALB_RS25205 ^@ http://purl.uniprot.org/uniprot/W5WD23 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS21135 ^@ http://purl.uniprot.org/uniprot/W5W967 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS21765 ^@ http://purl.uniprot.org/uniprot/W5WAJ4 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1449976:KALB_RS14160 ^@ http://purl.uniprot.org/uniprot/W5W5R3 ^@ Similarity|||Subunit ^@ Belongs to the methylmalonyl-CoA mutase family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1449976:KALB_RS04125 ^@ http://purl.uniprot.org/uniprot/W5W0B0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1449976:KALB_RS17675 ^@ http://purl.uniprot.org/uniprot/W5W861 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/1449976:KALB_RS01245 ^@ http://purl.uniprot.org/uniprot/W5VZD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS12930 ^@ http://purl.uniprot.org/uniprot/W5W506 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42080 ^@ http://purl.uniprot.org/uniprot/W5WMY2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS08495 ^@ http://purl.uniprot.org/uniprot/W5W2L1 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/1449976:KALB_RS09680 ^@ http://purl.uniprot.org/uniprot/W5W3B4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS10925 ^@ http://purl.uniprot.org/uniprot/W5W547 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS49170 ^@ http://purl.uniprot.org/uniprot/W5W7A2 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1449976:KALB_RS07225 ^@ http://purl.uniprot.org/uniprot/W5W212 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08040 ^@ http://purl.uniprot.org/uniprot/W5W1E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS28500 ^@ http://purl.uniprot.org/uniprot/W5WF18 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS15335 ^@ http://purl.uniprot.org/uniprot/W5W6C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PhyH family. EctD subfamily.|||Homodimer.|||Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine. http://togogenome.org/gene/1449976:KALB_RS07180 ^@ http://purl.uniprot.org/uniprot/W5W2U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS19535 ^@ http://purl.uniprot.org/uniprot/W5W9U8 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1449976:KALB_RS43700 ^@ http://purl.uniprot.org/uniprot/W5W2U0 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS09655 ^@ http://purl.uniprot.org/uniprot/W5W3A6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1449976:KALB_RS43115 ^@ http://purl.uniprot.org/uniprot/W5WMQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1449976:KALB_RS11655 ^@ http://purl.uniprot.org/uniprot/W5W3F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS14515 ^@ http://purl.uniprot.org/uniprot/W5WDN0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1449976:KALB_RS22105 ^@ http://purl.uniprot.org/uniprot/W5W9N2 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1449976:KALB_RS36975 ^@ http://purl.uniprot.org/uniprot/W5WJ29 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1449976:KALB_RS10695 ^@ http://purl.uniprot.org/uniprot/W5W430 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06200 ^@ http://purl.uniprot.org/uniprot/W5W0D7 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1449976:KALB_RS01415 ^@ http://purl.uniprot.org/uniprot/W5W666 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1449976:KALB_RS48920 ^@ http://purl.uniprot.org/uniprot/W5WJ09 ^@ Similarity|||Subunit ^@ Belongs to the aminoglycoside phosphotransferase family.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS34020 ^@ http://purl.uniprot.org/uniprot/W5WI70 ^@ Similarity ^@ Belongs to the peptidase S15 family. http://togogenome.org/gene/1449976:KALB_RS00545 ^@ http://purl.uniprot.org/uniprot/W5VYG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1449976:KALB_RS23630 ^@ http://purl.uniprot.org/uniprot/W5WBD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS35910 ^@ http://purl.uniprot.org/uniprot/W5WR87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1449976:KALB_RS14410 ^@ http://purl.uniprot.org/uniprot/W5W5U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS32055 ^@ http://purl.uniprot.org/uniprot/W5WH11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS02550 ^@ http://purl.uniprot.org/uniprot/W5VZ79 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/1449976:KALB_RS39120 ^@ http://purl.uniprot.org/uniprot/W5WKM5 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1449976:KALB_RS44470 ^@ http://purl.uniprot.org/uniprot/W5WGA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42715 ^@ http://purl.uniprot.org/uniprot/W5WV54 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS13915 ^@ http://purl.uniprot.org/uniprot/W5W4M8 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/1449976:KALB_RS30690 ^@ http://purl.uniprot.org/uniprot/W5WN49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS19975 ^@ http://purl.uniprot.org/uniprot/W5W9G6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS22950 ^@ http://purl.uniprot.org/uniprot/W5WIL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EfeM/EfeO family.|||Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS29945 ^@ http://purl.uniprot.org/uniprot/W5WFC4 ^@ Similarity ^@ Belongs to the UPF0303 family. http://togogenome.org/gene/1449976:KALB_RS05545 ^@ http://purl.uniprot.org/uniprot/W5W0X5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1449976:KALB_RS35350 ^@ http://purl.uniprot.org/uniprot/W5WI73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS33535 ^@ http://purl.uniprot.org/uniprot/W5WHY2 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/1449976:KALB_RS39885 ^@ http://purl.uniprot.org/uniprot/W5WLM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1449976:KALB_RS49480 ^@ http://purl.uniprot.org/uniprot/W5WDN5 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS36555 ^@ http://purl.uniprot.org/uniprot/W5WJQ1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS21665 ^@ http://purl.uniprot.org/uniprot/W5WAH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.|||Belongs to the glycosyl hydrolase 46 family.|||Secreted http://togogenome.org/gene/1449976:KALB_RS17195 ^@ http://purl.uniprot.org/uniprot/W5WF96 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS03875 ^@ http://purl.uniprot.org/uniprot/W5W0V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1449976:KALB_RS42210 ^@ http://purl.uniprot.org/uniprot/W5WM39 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS18935 ^@ http://purl.uniprot.org/uniprot/W5W8G2 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/1449976:KALB_RS16735 ^@ http://purl.uniprot.org/uniprot/W5W6C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS06180 ^@ http://purl.uniprot.org/uniprot/W5W8Y9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1449976:KALB_RS10015 ^@ http://purl.uniprot.org/uniprot/W5WB20 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS25215 ^@ http://purl.uniprot.org/uniprot/W5WBD2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40440 ^@ http://purl.uniprot.org/uniprot/W5WK51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS29660 ^@ http://purl.uniprot.org/uniprot/W5WMJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS31530 ^@ http://purl.uniprot.org/uniprot/W5WG04 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS03465 ^@ http://purl.uniprot.org/uniprot/W5VZY3 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/1449976:KALB_RS01095 ^@ http://purl.uniprot.org/uniprot/W5VYE8 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1449976:KALB_RS42160 ^@ http://purl.uniprot.org/uniprot/W5WM30 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1449976:KALB_RS11755 ^@ http://purl.uniprot.org/uniprot/W5W4F4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS21300 ^@ http://purl.uniprot.org/uniprot/W5W9U0 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS39435 ^@ http://purl.uniprot.org/uniprot/W5WT96 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS27420 ^@ http://purl.uniprot.org/uniprot/W5WCQ6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1449976:KALB_RS35140 ^@ http://purl.uniprot.org/uniprot/W5WQQ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS32445 ^@ http://purl.uniprot.org/uniprot/W5WP53 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1449976:KALB_RS00180 ^@ http://purl.uniprot.org/uniprot/W5VXW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15865 ^@ http://purl.uniprot.org/uniprot/W5W7P1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS39735 ^@ http://purl.uniprot.org/uniprot/W5WKZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/1449976:KALB_RS27590 ^@ http://purl.uniprot.org/uniprot/W5WCT2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS39335 ^@ http://purl.uniprot.org/uniprot/W5WT75 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1449976:KALB_RS13825 ^@ http://purl.uniprot.org/uniprot/W5W5Z4 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1449976:KALB_RS25055 ^@ http://purl.uniprot.org/uniprot/W5WCZ8 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/1449976:KALB_RS27765 ^@ http://purl.uniprot.org/uniprot/W5WEI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1449976:KALB_RS33920 ^@ http://purl.uniprot.org/uniprot/W5WI52 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1449976:KALB_RS38855 ^@ http://purl.uniprot.org/uniprot/W5WK79 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1449976:KALB_RS35810 ^@ http://purl.uniprot.org/uniprot/W5WR69 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1449976:KALB_RS14985 ^@ http://purl.uniprot.org/uniprot/W5W6K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS40095 ^@ http://purl.uniprot.org/uniprot/W5WTM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1449976:KALB_RS08385 ^@ http://purl.uniprot.org/uniprot/W5W2P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS16910 ^@ http://purl.uniprot.org/uniprot/W5W6F6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS13740 ^@ http://purl.uniprot.org/uniprot/W5W4J7 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1449976:KALB_RS15715 ^@ http://purl.uniprot.org/uniprot/W5W6K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS43290 ^@ http://purl.uniprot.org/uniprot/W5WMU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS22165 ^@ http://purl.uniprot.org/uniprot/W5WAR3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS16875 ^@ http://purl.uniprot.org/uniprot/W5W8B5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS01885 ^@ http://purl.uniprot.org/uniprot/W5VY04 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1449976:KALB_RS01375 ^@ http://purl.uniprot.org/uniprot/W5VYM1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1449976:KALB_RS35805 ^@ http://purl.uniprot.org/uniprot/W5WHI7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1449976:KALB_RS40785 ^@ http://purl.uniprot.org/uniprot/W5WMB2 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1449976:KALB_RS30540 ^@ http://purl.uniprot.org/uniprot/W5WN19 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1449976:KALB_RS29225 ^@ http://purl.uniprot.org/uniprot/W5WDQ2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS36440 ^@ http://purl.uniprot.org/uniprot/W5WHU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1449976:KALB_RS35970 ^@ http://purl.uniprot.org/uniprot/W5WJE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS27760 ^@ http://purl.uniprot.org/uniprot/W5WE20 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS14870 ^@ http://purl.uniprot.org/uniprot/W5W622 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS40355 ^@ http://purl.uniprot.org/uniprot/W5WLY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1449976:KALB_RS13605 ^@ http://purl.uniprot.org/uniprot/W5W6K8 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1449976:KALB_RS43365 ^@ http://purl.uniprot.org/uniprot/W5WMV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07590 ^@ http://purl.uniprot.org/uniprot/W5W9N0 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1449976:KALB_RS30590 ^@ http://purl.uniprot.org/uniprot/W5WN29 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS02805 ^@ http://purl.uniprot.org/uniprot/W5VYF5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1449976:KALB_RS33090 ^@ http://purl.uniprot.org/uniprot/W5WH65 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/1449976:KALB_RS14510 ^@ http://purl.uniprot.org/uniprot/W5W4Z8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS33505 ^@ http://purl.uniprot.org/uniprot/W5WHG5 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1449976:KALB_RS37975 ^@ http://purl.uniprot.org/uniprot/W5WIQ3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS01660 ^@ http://purl.uniprot.org/uniprot/W5W6A4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS26390 ^@ http://purl.uniprot.org/uniprot/W5WDU1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1449976:KALB_RS00840 ^@ http://purl.uniprot.org/uniprot/W5W5S0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1449976:KALB_RS25405 ^@ http://purl.uniprot.org/uniprot/W5WC86 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS00275 ^@ http://purl.uniprot.org/uniprot/W5VYP4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS07820 ^@ http://purl.uniprot.org/uniprot/W5W9S4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1449976:KALB_RS01840 ^@ http://purl.uniprot.org/uniprot/W5W6D3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1449976:KALB_RS01400 ^@ http://purl.uniprot.org/uniprot/W5VZG2 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1449976:KALB_RS10650 ^@ http://purl.uniprot.org/uniprot/W5W4Y7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS32725 ^@ http://purl.uniprot.org/uniprot/W5WHD3 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1449976:KALB_RS36490 ^@ http://purl.uniprot.org/uniprot/W5WHV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42485 ^@ http://purl.uniprot.org/uniprot/W5WM95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS32480 ^@ http://purl.uniprot.org/uniprot/W5WH91 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1449976:KALB_RS16075 ^@ http://purl.uniprot.org/uniprot/W5W5W0 ^@ Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. http://togogenome.org/gene/1449976:KALB_RS20800 ^@ http://purl.uniprot.org/uniprot/W5W8V4 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS41565 ^@ http://purl.uniprot.org/uniprot/W5WKS4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS03585 ^@ http://purl.uniprot.org/uniprot/W5VYU4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1449976:KALB_RS36270 ^@ http://purl.uniprot.org/uniprot/W5WIS0 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1449976:KALB_RS08940 ^@ http://purl.uniprot.org/uniprot/W5W413 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1449976:KALB_RS02785 ^@ http://purl.uniprot.org/uniprot/W5W6U9 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS17940 ^@ http://purl.uniprot.org/uniprot/W5W8V2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protease inhibitor I16 (SSI) family.|||Homodimer.|||Secreted http://togogenome.org/gene/1449976:KALB_RS40385 ^@ http://purl.uniprot.org/uniprot/W5WL50 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1449976:KALB_RS12960 ^@ http://purl.uniprot.org/uniprot/W5W422 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm|||In the C-terminal section; belongs to the UPF0157 (GrpB) family.|||In the N-terminal section; belongs to the CoaE family. http://togogenome.org/gene/1449976:KALB_RS28025 ^@ http://purl.uniprot.org/uniprot/W5WLL9 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1449976:KALB_RS16635 ^@ http://purl.uniprot.org/uniprot/W5W757 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS25225 ^@ http://purl.uniprot.org/uniprot/W5WCK1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS42535 ^@ http://purl.uniprot.org/uniprot/W5WMA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1449976:KALB_RS13750 ^@ http://purl.uniprot.org/uniprot/W5W5Y4 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1449976:KALB_RS17980 ^@ http://purl.uniprot.org/uniprot/W5WFP2 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1449976:KALB_RS29060 ^@ http://purl.uniprot.org/uniprot/W5WM77 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS28590 ^@ http://purl.uniprot.org/uniprot/W5WM07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13570 ^@ http://purl.uniprot.org/uniprot/W5WD22 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1449976:KALB_RS33220 ^@ http://purl.uniprot.org/uniprot/W5WHQ9 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1449976:KALB_RS47335 ^@ http://purl.uniprot.org/uniprot/W5WKV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS06220 ^@ http://purl.uniprot.org/uniprot/W5W1E1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1449976:KALB_RS02610 ^@ http://purl.uniprot.org/uniprot/W5W6Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS31645 ^@ http://purl.uniprot.org/uniprot/W5WGC0 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1449976:KALB_RS31860 ^@ http://purl.uniprot.org/uniprot/W5WG55 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1449976:KALB_RS08855 ^@ http://purl.uniprot.org/uniprot/W5WAG4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1449976:KALB_RS16415 ^@ http://purl.uniprot.org/uniprot/W5W836 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1449976:KALB_RS14990 ^@ http://purl.uniprot.org/uniprot/W5W779 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1449976:KALB_RS13900 ^@ http://purl.uniprot.org/uniprot/W5W603 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1449976:KALB_RS05305 ^@ http://purl.uniprot.org/uniprot/W5W1L7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.|||Cell membrane|||Cytoplasm|||Homodimer.|||In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.|||In the N-terminal section; belongs to the LPG synthetase family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS38560 ^@ http://purl.uniprot.org/uniprot/W5WK33 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS34250 ^@ http://purl.uniprot.org/uniprot/W5WHU9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS40085 ^@ http://purl.uniprot.org/uniprot/W5WKY2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS17750 ^@ http://purl.uniprot.org/uniprot/W5W873 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS22025 ^@ http://purl.uniprot.org/uniprot/W5WA68 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1449976:KALB_RS12395 ^@ http://purl.uniprot.org/uniprot/W5W4R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS18725 ^@ http://purl.uniprot.org/uniprot/W5W8V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Mitochondrion matrix http://togogenome.org/gene/1449976:KALB_RS44190 ^@ http://purl.uniprot.org/uniprot/W5WBL6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS36425 ^@ http://purl.uniprot.org/uniprot/W5WJ55 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1449976:KALB_RS04720 ^@ http://purl.uniprot.org/uniprot/W5W0L8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1449976:KALB_RS17730 ^@ http://purl.uniprot.org/uniprot/W5W8S0 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1449976:KALB_RS33950 ^@ http://purl.uniprot.org/uniprot/W5WHE2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS31695 ^@ http://purl.uniprot.org/uniprot/W5WF26 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS01830 ^@ http://purl.uniprot.org/uniprot/W5VYV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS25665 ^@ http://purl.uniprot.org/uniprot/W5WK62 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/1449976:KALB_RS32525 ^@ http://purl.uniprot.org/uniprot/W5WGV0 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1449976:KALB_RS08740 ^@ http://purl.uniprot.org/uniprot/W5W304 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS41540 ^@ http://purl.uniprot.org/uniprot/W5WKR9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1449976:KALB_RS41895 ^@ http://purl.uniprot.org/uniprot/W5WUP4 ^@ Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the nitrobindin family.|||Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.|||Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.|||Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo. http://togogenome.org/gene/1449976:KALB_RS31690 ^@ http://purl.uniprot.org/uniprot/W5WG21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS40470 ^@ http://purl.uniprot.org/uniprot/W5WTV7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS03555 ^@ http://purl.uniprot.org/uniprot/W5VZU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1449976:KALB_RS40380 ^@ http://purl.uniprot.org/uniprot/W5WLY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS39675 ^@ http://purl.uniprot.org/uniprot/W5WKN5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS18580 ^@ http://purl.uniprot.org/uniprot/W5W9A0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS18055 ^@ http://purl.uniprot.org/uniprot/W5WFQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1449976:KALB_RS05300 ^@ http://purl.uniprot.org/uniprot/W5W0X3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1449976:KALB_RS40605 ^@ http://purl.uniprot.org/uniprot/W5WM65 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1449976:KALB_RS13860 ^@ http://purl.uniprot.org/uniprot/W5W5L3 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS40580 ^@ http://purl.uniprot.org/uniprot/W5WL93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1449976:KALB_RS33665 ^@ http://purl.uniprot.org/uniprot/W5WPX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS33160 ^@ http://purl.uniprot.org/uniprot/W5WPJ3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1449976:KALB_RS27150 ^@ http://purl.uniprot.org/uniprot/W5WE69 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS31205 ^@ http://purl.uniprot.org/uniprot/W5WNI1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1449976:KALB_RS39525 ^@ http://purl.uniprot.org/uniprot/W5WKK8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1449976:KALB_RS28690 ^@ http://purl.uniprot.org/uniprot/W5WEM3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS29920 ^@ http://purl.uniprot.org/uniprot/W5WFS0 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1449976:KALB_RS26790 ^@ http://purl.uniprot.org/uniprot/W5WKW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS09875 ^@ http://purl.uniprot.org/uniprot/W5W4H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS39500 ^@ http://purl.uniprot.org/uniprot/W5WKK0 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1449976:KALB_RS06080 ^@ http://purl.uniprot.org/uniprot/W5W078 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1449976:KALB_RS15465 ^@ http://purl.uniprot.org/uniprot/W5W7F3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS00920 ^@ http://purl.uniprot.org/uniprot/W5W5T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS42020 ^@ http://purl.uniprot.org/uniprot/W5WUR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS02015 ^@ http://purl.uniprot.org/uniprot/W5W6G8 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/1449976:KALB_RS19405 ^@ http://purl.uniprot.org/uniprot/W5W817 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS30700 ^@ http://purl.uniprot.org/uniprot/W5WG66 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS01850 ^@ http://purl.uniprot.org/uniprot/W5VZP2 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1449976:KALB_RS31715 ^@ http://purl.uniprot.org/uniprot/W5WG28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS20375 ^@ http://purl.uniprot.org/uniprot/W5WAA5 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/1449976:KALB_RS12640 ^@ http://purl.uniprot.org/uniprot/W5W5Z5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS10480 ^@ http://purl.uniprot.org/uniprot/W5W4U6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS04380 ^@ http://purl.uniprot.org/uniprot/W5W0F4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS17035 ^@ http://purl.uniprot.org/uniprot/W5W6H8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS16390 ^@ http://purl.uniprot.org/uniprot/W5W831 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS25315 ^@ http://purl.uniprot.org/uniprot/W5WBF5 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/1449976:KALB_RS14800 ^@ http://purl.uniprot.org/uniprot/W5W556 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42240 ^@ http://purl.uniprot.org/uniprot/W5WL54 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1449976:KALB_RS03955 ^@ http://purl.uniprot.org/uniprot/W5W0X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07710 ^@ http://purl.uniprot.org/uniprot/W5W181 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/1449976:KALB_RS14385 ^@ http://purl.uniprot.org/uniprot/W5W5U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS35945 ^@ http://purl.uniprot.org/uniprot/W5WJD7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1449976:KALB_RS43425 ^@ http://purl.uniprot.org/uniprot/W5WVM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS06140 ^@ http://purl.uniprot.org/uniprot/W5W271 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1449976:KALB_RS04575 ^@ http://purl.uniprot.org/uniprot/W5W0I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS21630 ^@ http://purl.uniprot.org/uniprot/W5W9F2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS35425 ^@ http://purl.uniprot.org/uniprot/W5WI88 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/1449976:KALB_RS40445 ^@ http://purl.uniprot.org/uniprot/W5WTU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1449976:KALB_RS26990 ^@ http://purl.uniprot.org/uniprot/W5WL02 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS07545 ^@ http://purl.uniprot.org/uniprot/W5W274 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS13040 ^@ http://purl.uniprot.org/uniprot/W5W533 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1449976:KALB_RS01890 ^@ http://purl.uniprot.org/uniprot/W5W6E3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1449976:KALB_RS07835 ^@ http://purl.uniprot.org/uniprot/W5W275 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1449976:KALB_RS42740 ^@ http://purl.uniprot.org/uniprot/W5WV58 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS03120 ^@ http://purl.uniprot.org/uniprot/W5W0A4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40875 ^@ http://purl.uniprot.org/uniprot/W5WU60 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS07865 ^@ http://purl.uniprot.org/uniprot/W5W1A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1449976:KALB_RS07050 ^@ http://purl.uniprot.org/uniprot/W5W9C8 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS07795 ^@ http://purl.uniprot.org/uniprot/W5W196 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS43075 ^@ http://purl.uniprot.org/uniprot/W5WVD2 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1449976:KALB_RS41655 ^@ http://purl.uniprot.org/uniprot/W5WLT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42635 ^@ http://purl.uniprot.org/uniprot/W5WML8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS11195 ^@ http://purl.uniprot.org/uniprot/W5WBT0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1449976:KALB_RS22955 ^@ http://purl.uniprot.org/uniprot/W5WB64 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/1449976:KALB_RS40425 ^@ http://purl.uniprot.org/uniprot/W5WLD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1449976:KALB_RS02765 ^@ http://purl.uniprot.org/uniprot/W5VZL1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1449976:KALB_RS24785 ^@ http://purl.uniprot.org/uniprot/W5WCU9 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1449976:KALB_RS27645 ^@ http://purl.uniprot.org/uniprot/W5WLD5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS34615 ^@ http://purl.uniprot.org/uniprot/W5WI27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1449976:KALB_RS35120 ^@ http://purl.uniprot.org/uniprot/W5WID4 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1449976:KALB_RS32145 ^@ http://purl.uniprot.org/uniprot/W5WGM1 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS18390 ^@ http://purl.uniprot.org/uniprot/W5W937 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS16215 ^@ http://purl.uniprot.org/uniprot/W5W7Z8 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1449976:KALB_RS13160 ^@ http://purl.uniprot.org/uniprot/W5W695 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS04750 ^@ http://purl.uniprot.org/uniprot/W5W1C0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS13615 ^@ http://purl.uniprot.org/uniprot/W5W4H5 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1449976:KALB_RS17640 ^@ http://purl.uniprot.org/uniprot/W5W6W3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1449976:KALB_RS10710 ^@ http://purl.uniprot.org/uniprot/W5W2W8 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1449976:KALB_RS25020 ^@ http://purl.uniprot.org/uniprot/W5WB94 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS36135 ^@ http://purl.uniprot.org/uniprot/W5WRC7 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/1449976:KALB_RS15585 ^@ http://purl.uniprot.org/uniprot/W5W7I3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS06440 ^@ http://purl.uniprot.org/uniprot/W5W2G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1449976:KALB_RS42515 ^@ http://purl.uniprot.org/uniprot/W5WLA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS16820 ^@ http://purl.uniprot.org/uniprot/W5W7R0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS36420 ^@ http://purl.uniprot.org/uniprot/W5WRH3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS28035 ^@ http://purl.uniprot.org/uniprot/W5WEN4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS14095 ^@ http://purl.uniprot.org/uniprot/W5WDE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/1449976:KALB_RS03255 ^@ http://purl.uniprot.org/uniprot/W5VZL8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS00850 ^@ http://purl.uniprot.org/uniprot/W5VZ13 ^@ Similarity|||Subunit ^@ Belongs to the Bpa family.|||Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings. http://togogenome.org/gene/1449976:KALB_RS18310 ^@ http://purl.uniprot.org/uniprot/W5WFV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS40205 ^@ http://purl.uniprot.org/uniprot/W5WLU6 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1449976:KALB_RS42700 ^@ http://purl.uniprot.org/uniprot/W5WN92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS35745 ^@ http://purl.uniprot.org/uniprot/W5WJ96 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1449976:KALB_RS18010 ^@ http://purl.uniprot.org/uniprot/W5W8W6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS34570 ^@ http://purl.uniprot.org/uniprot/W5WIH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS23430 ^@ http://purl.uniprot.org/uniprot/W5WC50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS15340 ^@ http://purl.uniprot.org/uniprot/W5W5F2 ^@ Function|||Similarity ^@ Belongs to the ectoine synthase family.|||Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. http://togogenome.org/gene/1449976:KALB_RS07535 ^@ http://purl.uniprot.org/uniprot/W5W145 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1449976:KALB_RS32730 ^@ http://purl.uniprot.org/uniprot/W5WGN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1449976:KALB_RS09935 ^@ http://purl.uniprot.org/uniprot/W5W2H5 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1449976:KALB_RS16020 ^@ http://purl.uniprot.org/uniprot/W5W6S3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1449976:KALB_RS31130 ^@ http://purl.uniprot.org/uniprot/W5WNG6 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1449976:KALB_RS40020 ^@ http://purl.uniprot.org/uniprot/W5WTL1 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS31300 ^@ http://purl.uniprot.org/uniprot/W5WNJ8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1449976:KALB_RS39350 ^@ http://purl.uniprot.org/uniprot/W5WKG8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/1449976:KALB_RS43515 ^@ http://purl.uniprot.org/uniprot/W5WMX6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1449976:KALB_RS09815 ^@ http://purl.uniprot.org/uniprot/W5WAX0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1449976:KALB_RS06470 ^@ http://purl.uniprot.org/uniprot/W5W1I9 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS03070 ^@ http://purl.uniprot.org/uniprot/W5W096 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS03415 ^@ http://purl.uniprot.org/uniprot/W5W768 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1449976:KALB_RS27215 ^@ http://purl.uniprot.org/uniprot/W5WDQ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS39945 ^@ http://purl.uniprot.org/uniprot/W5WTJ5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1449976:KALB_RS05855 ^@ http://purl.uniprot.org/uniprot/W5W035 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS16330 ^@ http://purl.uniprot.org/uniprot/W5WET9 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS38760 ^@ http://purl.uniprot.org/uniprot/W5WJ69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1449976:KALB_RS26655 ^@ http://purl.uniprot.org/uniprot/W5WKT3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS40835 ^@ http://purl.uniprot.org/uniprot/W5WMB9 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/1449976:KALB_RS10995 ^@ http://purl.uniprot.org/uniprot/W5W485 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS37000 ^@ http://purl.uniprot.org/uniprot/W5WJ35 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS37045 ^@ http://purl.uniprot.org/uniprot/W5WJZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15420 ^@ http://purl.uniprot.org/uniprot/W5W6E1 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1449976:KALB_RS36875 ^@ http://purl.uniprot.org/uniprot/W5WJV4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/1449976:KALB_RS43145 ^@ http://purl.uniprot.org/uniprot/W5WLQ5 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS03725 ^@ http://purl.uniprot.org/uniprot/W5W0T1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1449976:KALB_RS30790 ^@ http://purl.uniprot.org/uniprot/W5WFY2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS31215 ^@ http://purl.uniprot.org/uniprot/W5WGK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1449976:KALB_RS09705 ^@ http://purl.uniprot.org/uniprot/W5W3B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1449976:KALB_RS04775 ^@ http://purl.uniprot.org/uniprot/W5W1C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/1449976:KALB_RS23125 ^@ http://purl.uniprot.org/uniprot/W5WBW8 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1449976:KALB_RS32810 ^@ http://purl.uniprot.org/uniprot/W5WPC2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1449976:KALB_RS30270 ^@ http://purl.uniprot.org/uniprot/W5WMW7 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1449976:KALB_RS02725 ^@ http://purl.uniprot.org/uniprot/W5VZB3 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1449976:KALB_RS13960 ^@ http://purl.uniprot.org/uniprot/W5W5N1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS13920 ^@ http://purl.uniprot.org/uniprot/W5WDB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1449976:KALB_RS31310 ^@ http://purl.uniprot.org/uniprot/W5WGM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS35955 ^@ http://purl.uniprot.org/uniprot/W5WHL6 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1449976:KALB_RS31705 ^@ http://purl.uniprot.org/uniprot/W5WGD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS02355 ^@ http://purl.uniprot.org/uniprot/W5VY84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS43655 ^@ http://purl.uniprot.org/uniprot/W5W118 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/1449976:KALB_RS09600 ^@ http://purl.uniprot.org/uniprot/W5W3G2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS05525 ^@ http://purl.uniprot.org/uniprot/W5VZX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS39730 ^@ http://purl.uniprot.org/uniprot/W5WTF2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS20540 ^@ http://purl.uniprot.org/uniprot/W5WH69 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1449976:KALB_RS03830 ^@ http://purl.uniprot.org/uniprot/W5W021 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS41610 ^@ http://purl.uniprot.org/uniprot/W5WKT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS06865 ^@ http://purl.uniprot.org/uniprot/W5W2P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS49190 ^@ http://purl.uniprot.org/uniprot/W5W7L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS10255 ^@ http://purl.uniprot.org/uniprot/W5W2P0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS39255 ^@ http://purl.uniprot.org/uniprot/W5WJG6 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1449976:KALB_RS30160 ^@ http://purl.uniprot.org/uniprot/W5WE80 ^@ Similarity ^@ Belongs to the amidinotransferase family. http://togogenome.org/gene/1449976:KALB_RS40805 ^@ http://purl.uniprot.org/uniprot/W5WLN0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS34780 ^@ http://purl.uniprot.org/uniprot/W5WGW2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS04995 ^@ http://purl.uniprot.org/uniprot/W5W835 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40295 ^@ http://purl.uniprot.org/uniprot/W5WTR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1449976:KALB_RS03035 ^@ http://purl.uniprot.org/uniprot/W5W6Z0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1449976:KALB_RS31825 ^@ http://purl.uniprot.org/uniprot/W5WGF4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS07090 ^@ http://purl.uniprot.org/uniprot/W5W1S7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS05335 ^@ http://purl.uniprot.org/uniprot/W5VZU9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1449976:KALB_RS34895 ^@ http://purl.uniprot.org/uniprot/W5WIP1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1449976:KALB_RS21890 ^@ http://purl.uniprot.org/uniprot/W5WAL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS43490 ^@ http://purl.uniprot.org/uniprot/W5WMX3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1449976:KALB_RS34850 ^@ http://purl.uniprot.org/uniprot/W5WHV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1449976:KALB_RS00060 ^@ http://purl.uniprot.org/uniprot/W5VX26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS39720 ^@ http://purl.uniprot.org/uniprot/W5WLJ2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS34685 ^@ http://purl.uniprot.org/uniprot/W5WI41 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1449976:KALB_RS11370 ^@ http://purl.uniprot.org/uniprot/W5WGT0 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1449976:KALB_RS00890 ^@ http://purl.uniprot.org/uniprot/W5W5S9 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1449976:KALB_RS11405 ^@ http://purl.uniprot.org/uniprot/W5W4I9 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS32900 ^@ http://purl.uniprot.org/uniprot/W5WGS1 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS42500 ^@ http://purl.uniprot.org/uniprot/W5WMJ2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1449976:KALB_RS42015 ^@ http://purl.uniprot.org/uniprot/W5WL07 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1449976:KALB_RS35345 ^@ http://purl.uniprot.org/uniprot/W5WIW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13350 ^@ http://purl.uniprot.org/uniprot/W5WCX3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1449976:KALB_RS33550 ^@ http://purl.uniprot.org/uniprot/W5WPU9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS04425 ^@ http://purl.uniprot.org/uniprot/W5W7S1 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1449976:KALB_RS08985 ^@ http://purl.uniprot.org/uniprot/W5W339 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS17610 ^@ http://purl.uniprot.org/uniprot/W5W8Q0 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS21245 ^@ http://purl.uniprot.org/uniprot/W5WAY7 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1449976:KALB_RS34995 ^@ http://purl.uniprot.org/uniprot/W5WQM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1449976:KALB_RS12755 ^@ http://purl.uniprot.org/uniprot/W5WCK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS41040 ^@ http://purl.uniprot.org/uniprot/W5WLJ3 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1449976:KALB_RS34890 ^@ http://purl.uniprot.org/uniprot/W5WI82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS07195 ^@ http://purl.uniprot.org/uniprot/W5W9F4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1449976:KALB_RS18730 ^@ http://purl.uniprot.org/uniprot/W5W9F3 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1449976:KALB_RS37075 ^@ http://purl.uniprot.org/uniprot/W5WJ49 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1449976:KALB_RS36395 ^@ http://purl.uniprot.org/uniprot/W5WJ51 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1449976:KALB_RS20560 ^@ http://purl.uniprot.org/uniprot/W5W8R1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS02165 ^@ http://purl.uniprot.org/uniprot/W5W6J1 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1449976:KALB_RS13190 ^@ http://purl.uniprot.org/uniprot/W5W562 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS39520 ^@ http://purl.uniprot.org/uniprot/W5WLF4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1449976:KALB_RS32110 ^@ http://purl.uniprot.org/uniprot/W5WFB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS20370 ^@ http://purl.uniprot.org/uniprot/W5W9P1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS29010 ^@ http://purl.uniprot.org/uniprot/W5WM70 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS39055 ^@ http://purl.uniprot.org/uniprot/W5WKA9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS35800 ^@ http://purl.uniprot.org/uniprot/W5WIJ3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1449976:KALB_RS29455 ^@ http://purl.uniprot.org/uniprot/W5WDU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS07975 ^@ http://purl.uniprot.org/uniprot/W5W2G8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS20680 ^@ http://purl.uniprot.org/uniprot/W5WAG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1449976:KALB_RS23765 ^@ http://purl.uniprot.org/uniprot/W5WAP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS19835 ^@ http://purl.uniprot.org/uniprot/W5W8V3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1449976:KALB_RS09585 ^@ http://purl.uniprot.org/uniprot/W5W386 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15590 ^@ http://purl.uniprot.org/uniprot/W5W6I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS33225 ^@ http://purl.uniprot.org/uniprot/W5WH07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS31680 ^@ http://purl.uniprot.org/uniprot/W5WGC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS11415 ^@ http://purl.uniprot.org/uniprot/W5W4B5 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1449976:KALB_RS10790 ^@ http://purl.uniprot.org/uniprot/W5WBG2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS37785 ^@ http://purl.uniprot.org/uniprot/W5WSA0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS36075 ^@ http://purl.uniprot.org/uniprot/W5WIN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1449976:KALB_RS29460 ^@ http://purl.uniprot.org/uniprot/W5WMF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15935 ^@ http://purl.uniprot.org/uniprot/W5W758 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS41805 ^@ http://purl.uniprot.org/uniprot/W5WMT5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1449976:KALB_RS03710 ^@ http://purl.uniprot.org/uniprot/W5VYX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1449976:KALB_RS04355 ^@ http://purl.uniprot.org/uniprot/W5W0F0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS38705 ^@ http://purl.uniprot.org/uniprot/W5WL13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS34675 ^@ http://purl.uniprot.org/uniprot/W5WGU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS11805 ^@ http://purl.uniprot.org/uniprot/W5W4F9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1449976:KALB_RS09405 ^@ http://purl.uniprot.org/uniprot/W5W487 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1449976:KALB_RS40140 ^@ http://purl.uniprot.org/uniprot/W5WJY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/1449976:KALB_RS41305 ^@ http://purl.uniprot.org/uniprot/W5WLN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS19145 ^@ http://purl.uniprot.org/uniprot/W5W9M3 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1449976:KALB_RS14700 ^@ http://purl.uniprot.org/uniprot/W5W536 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS29690 ^@ http://purl.uniprot.org/uniprot/W5WF70 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS33500 ^@ http://purl.uniprot.org/uniprot/W5WPU2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1449976:KALB_RS37335 ^@ http://purl.uniprot.org/uniprot/W5WJN2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS07860 ^@ http://purl.uniprot.org/uniprot/W5W279 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1449976:KALB_RS09665 ^@ http://purl.uniprot.org/uniprot/W5WAU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1449976:KALB_RS36705 ^@ http://purl.uniprot.org/uniprot/W5WJS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1449976:KALB_RS14120 ^@ http://purl.uniprot.org/uniprot/W5WDF4 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1449976:KALB_RS18020 ^@ http://purl.uniprot.org/uniprot/W5W761 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1449976:KALB_RS21730 ^@ http://purl.uniprot.org/uniprot/W5W9H1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS35760 ^@ http://purl.uniprot.org/uniprot/W5WR60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS40570 ^@ http://purl.uniprot.org/uniprot/W5WLG5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1449976:KALB_RS16725 ^@ http://purl.uniprot.org/uniprot/W5W887 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS13810 ^@ http://purl.uniprot.org/uniprot/W5W5K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1449976:KALB_RS08950 ^@ http://purl.uniprot.org/uniprot/W5W210 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS05325 ^@ http://purl.uniprot.org/uniprot/W5W0Y0 ^@ Similarity ^@ Belongs to the LppX/LprAFG lipoprotein family. http://togogenome.org/gene/1449976:KALB_RS29520 ^@ http://purl.uniprot.org/uniprot/W5WFK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS33960 ^@ http://purl.uniprot.org/uniprot/W5WQ18 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS40750 ^@ http://purl.uniprot.org/uniprot/W5WU37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS01595 ^@ http://purl.uniprot.org/uniprot/W5VZJ9 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS15675 ^@ http://purl.uniprot.org/uniprot/W5WEC5 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1449976:KALB_RS23435 ^@ http://purl.uniprot.org/uniprot/W5WB09 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS39795 ^@ http://purl.uniprot.org/uniprot/W5WKQ6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS09545 ^@ http://purl.uniprot.org/uniprot/W5WAS3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1449976:KALB_RS19805 ^@ http://purl.uniprot.org/uniprot/W5WA03 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1449976:KALB_RS13200 ^@ http://purl.uniprot.org/uniprot/W5WCU0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS14355 ^@ http://purl.uniprot.org/uniprot/W5W6W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS27015 ^@ http://purl.uniprot.org/uniprot/W5WL09 ^@ Similarity ^@ Belongs to the darcynin family. http://togogenome.org/gene/1449976:KALB_RS20895 ^@ http://purl.uniprot.org/uniprot/W5WA11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS32345 ^@ http://purl.uniprot.org/uniprot/W5WP37 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1449976:KALB_RS20130 ^@ http://purl.uniprot.org/uniprot/W5WGZ3 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1449976:KALB_RS36520 ^@ http://purl.uniprot.org/uniprot/W5WRI8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1449976:KALB_RS10895 ^@ http://purl.uniprot.org/uniprot/W5W467 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS38850 ^@ http://purl.uniprot.org/uniprot/W5WL37 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1449976:KALB_RS21280 ^@ http://purl.uniprot.org/uniprot/W5W992 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1449976:KALB_RS43110 ^@ http://purl.uniprot.org/uniprot/W5WNL7 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS00080 ^@ http://purl.uniprot.org/uniprot/W5VXU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS00705 ^@ http://purl.uniprot.org/uniprot/W5VY73 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1449976:KALB_RS48885 ^@ http://purl.uniprot.org/uniprot/W5WHH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS11800 ^@ http://purl.uniprot.org/uniprot/W5W5L7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS16500 ^@ http://purl.uniprot.org/uniprot/W5W667 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/1449976:KALB_RS35325 ^@ http://purl.uniprot.org/uniprot/W5WI68 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1449976:KALB_RS38970 ^@ http://purl.uniprot.org/uniprot/W5WKJ6 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1449976:KALB_RS18105 ^@ http://purl.uniprot.org/uniprot/W5WFR9 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/1449976:KALB_RS23205 ^@ http://purl.uniprot.org/uniprot/W5WIR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1449976:KALB_RS16550 ^@ http://purl.uniprot.org/uniprot/W5WEX4 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1449976:KALB_RS20105 ^@ http://purl.uniprot.org/uniprot/W5W8Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1449976:KALB_RS29600 ^@ http://purl.uniprot.org/uniprot/W5WEW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1449976:KALB_RS17505 ^@ http://purl.uniprot.org/uniprot/W5W829 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1449976:KALB_RS33240 ^@ http://purl.uniprot.org/uniprot/W5WHC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS10270 ^@ http://purl.uniprot.org/uniprot/W5W4Q3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1449976:KALB_RS02780 ^@ http://purl.uniprot.org/uniprot/W5VYF3 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1449976:KALB_RS36680 ^@ http://purl.uniprot.org/uniprot/W5WJS3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1449976:KALB_RS09065 ^@ http://purl.uniprot.org/uniprot/W5W434 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1449976:KALB_RS10020 ^@ http://purl.uniprot.org/uniprot/W5W3P7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS37110 ^@ http://purl.uniprot.org/uniprot/W5WRV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS21325 ^@ http://purl.uniprot.org/uniprot/W5W9U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS36990 ^@ http://purl.uniprot.org/uniprot/W5WJG2 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS34725 ^@ http://purl.uniprot.org/uniprot/W5WGV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS02715 ^@ http://purl.uniprot.org/uniprot/W5VZK1 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1449976:KALB_RS30235 ^@ http://purl.uniprot.org/uniprot/W5WE98 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1449976:KALB_RS13150 ^@ http://purl.uniprot.org/uniprot/W5WCS9 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1449976:KALB_RS20555 ^@ http://purl.uniprot.org/uniprot/W5W985 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1449976:KALB_RS29680 ^@ http://purl.uniprot.org/uniprot/W5WDZ5 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1449976:KALB_RS29095 ^@ http://purl.uniprot.org/uniprot/W5WFC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS11030 ^@ http://purl.uniprot.org/uniprot/W5W328 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS02225 ^@ http://purl.uniprot.org/uniprot/W5VZC1 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1449976:KALB_RS00635 ^@ http://purl.uniprot.org/uniprot/W5VXD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS30205 ^@ http://purl.uniprot.org/uniprot/W5WF83 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1449976:KALB_RS35920 ^@ http://purl.uniprot.org/uniprot/W5WJD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS43480 ^@ http://purl.uniprot.org/uniprot/W5WN52 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1449976:KALB_RS23370 ^@ http://purl.uniprot.org/uniprot/W5WIU4 ^@ Similarity ^@ In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1449976:KALB_RS30145 ^@ http://purl.uniprot.org/uniprot/W5WFG9 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1449976:KALB_RS06005 ^@ http://purl.uniprot.org/uniprot/W5W062 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1449976:KALB_RS30125 ^@ http://purl.uniprot.org/uniprot/W5WFV6 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS33185 ^@ http://purl.uniprot.org/uniprot/W5WPJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS35850 ^@ http://purl.uniprot.org/uniprot/W5WIK3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1449976:KALB_RS06815 ^@ http://purl.uniprot.org/uniprot/W5W1T7 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1449976:KALB_RS42130 ^@ http://purl.uniprot.org/uniprot/W5WMZ0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1449976:KALB_RS31925 ^@ http://purl.uniprot.org/uniprot/W5WNV7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1449976:KALB_RS04410 ^@ http://purl.uniprot.org/uniprot/W5W157 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1449976:KALB_RS14530 ^@ http://purl.uniprot.org/uniprot/W5W5W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS09945 ^@ http://purl.uniprot.org/uniprot/W5WAZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15970 ^@ http://purl.uniprot.org/uniprot/W5W6R2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS30870 ^@ http://purl.uniprot.org/uniprot/W5WFQ5 ^@ Similarity ^@ Belongs to the peptidase M7 family. http://togogenome.org/gene/1449976:KALB_RS04740 ^@ http://purl.uniprot.org/uniprot/W5W7Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1449976:KALB_RS38105 ^@ http://purl.uniprot.org/uniprot/W5WSH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS01395 ^@ http://purl.uniprot.org/uniprot/W5VYZ3 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1449976:KALB_RS41145 ^@ http://purl.uniprot.org/uniprot/W5WLS9 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/1449976:KALB_RS00090 ^@ http://purl.uniprot.org/uniprot/W5W5A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/1449976:KALB_RS13115 ^@ http://purl.uniprot.org/uniprot/W5W548 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1449976:KALB_RS08235 ^@ http://purl.uniprot.org/uniprot/W5W2E7 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/1449976:KALB_RS09075 ^@ http://purl.uniprot.org/uniprot/W5W234 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1449976:KALB_RS07290 ^@ http://purl.uniprot.org/uniprot/W5W9H4 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS13885 ^@ http://purl.uniprot.org/uniprot/W5W5L8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1449976:KALB_RS02540 ^@ http://purl.uniprot.org/uniprot/W5VZH2 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS15295 ^@ http://purl.uniprot.org/uniprot/W5WE52 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS40780 ^@ http://purl.uniprot.org/uniprot/W5WLM7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1449976:KALB_RS13965 ^@ http://purl.uniprot.org/uniprot/W5W4N4 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/1449976:KALB_RS02655 ^@ http://purl.uniprot.org/uniprot/W5VYD2 ^@ Similarity ^@ Belongs to the CutC family. http://togogenome.org/gene/1449976:KALB_RS32470 ^@ http://purl.uniprot.org/uniprot/W5WP56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1449976:KALB_RS40660 ^@ http://purl.uniprot.org/uniprot/W5WLK6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS32535 ^@ http://purl.uniprot.org/uniprot/W5WGI8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1449976:KALB_RS36095 ^@ http://purl.uniprot.org/uniprot/W5WJG9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1449976:KALB_RS36655 ^@ http://purl.uniprot.org/uniprot/W5WJR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS14240 ^@ http://purl.uniprot.org/uniprot/W5W4T8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS39450 ^@ http://purl.uniprot.org/uniprot/W5WKJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36435 ^@ http://purl.uniprot.org/uniprot/W5WIU1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS05815 ^@ http://purl.uniprot.org/uniprot/W5W185 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1449976:KALB_RS06095 ^@ http://purl.uniprot.org/uniprot/W5W242 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS43450 ^@ http://purl.uniprot.org/uniprot/W5WVM6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS19720 ^@ http://purl.uniprot.org/uniprot/W5W884 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS24000 ^@ http://purl.uniprot.org/uniprot/W5WBT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS26840 ^@ http://purl.uniprot.org/uniprot/W5WDI0 ^@ Similarity ^@ Belongs to the acyltransferase PapA5 family. http://togogenome.org/gene/1449976:KALB_RS20550 ^@ http://purl.uniprot.org/uniprot/W5WAE0 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1449976:KALB_RS21510 ^@ http://purl.uniprot.org/uniprot/W5WHT4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1449976:KALB_RS37305 ^@ http://purl.uniprot.org/uniprot/W5WS00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS02825 ^@ http://purl.uniprot.org/uniprot/W5VZC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1449976:KALB_RS00460 ^@ http://purl.uniprot.org/uniprot/W5VX99 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1449976:KALB_RS09760 ^@ http://purl.uniprot.org/uniprot/W5W2E5 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS03770 ^@ http://purl.uniprot.org/uniprot/W5W7G2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS39660 ^@ http://purl.uniprot.org/uniprot/W5WTD8 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1449976:KALB_RS21685 ^@ http://purl.uniprot.org/uniprot/W5WHX1 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1449976:KALB_RS42105 ^@ http://purl.uniprot.org/uniprot/W5WMY6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1449976:KALB_RS40930 ^@ http://purl.uniprot.org/uniprot/W5WLP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS29530 ^@ http://purl.uniprot.org/uniprot/W5WDW4 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1449976:KALB_RS17400 ^@ http://purl.uniprot.org/uniprot/W5WFD3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1449976:KALB_RS10665 ^@ http://purl.uniprot.org/uniprot/W5WBD9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS13600 ^@ http://purl.uniprot.org/uniprot/W5W5U7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1449976:KALB_RS32490 ^@ http://purl.uniprot.org/uniprot/W5WFJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS04180 ^@ http://purl.uniprot.org/uniprot/W5W068 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1449976:KALB_RS08415 ^@ http://purl.uniprot.org/uniprot/W5W3M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS40650 ^@ http://purl.uniprot.org/uniprot/W5WKB5 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1449976:KALB_RS33785 ^@ http://purl.uniprot.org/uniprot/W5WGB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08395 ^@ http://purl.uniprot.org/uniprot/W5W2J0 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1449976:KALB_RS28265 ^@ http://purl.uniprot.org/uniprot/W5WLU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS13620 ^@ http://purl.uniprot.org/uniprot/W5WD60 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1449976:KALB_RS09525 ^@ http://purl.uniprot.org/uniprot/W5W3E7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS31250 ^@ http://purl.uniprot.org/uniprot/W5WEU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS37485 ^@ http://purl.uniprot.org/uniprot/W5WJR6 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1449976:KALB_RS10870 ^@ http://purl.uniprot.org/uniprot/W5W464 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS07670 ^@ http://purl.uniprot.org/uniprot/W5W295 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS35110 ^@ http://purl.uniprot.org/uniprot/W5WH28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15095 ^@ http://purl.uniprot.org/uniprot/W5W671 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1449976:KALB_RS18160 ^@ http://purl.uniprot.org/uniprot/W5W8F1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS17430 ^@ http://purl.uniprot.org/uniprot/W5W816 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS34680 ^@ http://purl.uniprot.org/uniprot/W5WQG3 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS36310 ^@ http://purl.uniprot.org/uniprot/W5WJ38 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1449976:KALB_RS36650 ^@ http://purl.uniprot.org/uniprot/W5WJ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS30675 ^@ http://purl.uniprot.org/uniprot/W5WG61 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS41135 ^@ http://purl.uniprot.org/uniprot/W5WKJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS35795 ^@ http://purl.uniprot.org/uniprot/W5WJA8 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/1449976:KALB_RS08990 ^@ http://purl.uniprot.org/uniprot/W5W423 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS01240 ^@ http://purl.uniprot.org/uniprot/W5VYX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS06790 ^@ http://purl.uniprot.org/uniprot/W5W1T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS37590 ^@ http://purl.uniprot.org/uniprot/W5WKA4 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1449976:KALB_RS36525 ^@ http://purl.uniprot.org/uniprot/W5WJ73 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1449976:KALB_RS31780 ^@ http://purl.uniprot.org/uniprot/W5WGW6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1449976:KALB_RS20420 ^@ http://purl.uniprot.org/uniprot/W5WH45 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1449976:KALB_RS35615 ^@ http://purl.uniprot.org/uniprot/W5WIP0 ^@ Function|||Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||May catalyze the transamination reaction in phenylalanine biosynthesis. http://togogenome.org/gene/1449976:KALB_RS22215 ^@ http://purl.uniprot.org/uniprot/W5WAS1 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1449976:KALB_RS28610 ^@ http://purl.uniprot.org/uniprot/W5WDF3 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1449976:KALB_RS41855 ^@ http://purl.uniprot.org/uniprot/W5WMU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1449976:KALB_RS38545 ^@ http://purl.uniprot.org/uniprot/W5WST0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS38710 ^@ http://purl.uniprot.org/uniprot/W5WK55 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1449976:KALB_RS09165 ^@ http://purl.uniprot.org/uniprot/W5W368 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS26295 ^@ http://purl.uniprot.org/uniprot/W5WKM1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1449976:KALB_RS39655 ^@ http://purl.uniprot.org/uniprot/W5WJP5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS09630 ^@ http://purl.uniprot.org/uniprot/W5W4C8 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1449976:KALB_RS10900 ^@ http://purl.uniprot.org/uniprot/W5W541 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1449976:KALB_RS04875 ^@ http://purl.uniprot.org/uniprot/W5VZK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1449976:KALB_RS39850 ^@ http://purl.uniprot.org/uniprot/W5WTH5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1449976:KALB_RS23320 ^@ http://purl.uniprot.org/uniprot/W5WAB7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS16930 ^@ http://purl.uniprot.org/uniprot/W5W7A1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1449976:KALB_RS13430 ^@ http://purl.uniprot.org/uniprot/W5W5N3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS38585 ^@ http://purl.uniprot.org/uniprot/W5WK38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS25380 ^@ http://purl.uniprot.org/uniprot/W5WC80 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1449976:KALB_RS29320 ^@ http://purl.uniprot.org/uniprot/W5WEQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1449976:KALB_RS28970 ^@ http://purl.uniprot.org/uniprot/W5WFA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS30115 ^@ http://purl.uniprot.org/uniprot/W5WMT2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS47855 ^@ http://purl.uniprot.org/uniprot/W5WFJ9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1449976:KALB_RS31370 ^@ http://purl.uniprot.org/uniprot/W5WEV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1449976:KALB_RS13070 ^@ http://purl.uniprot.org/uniprot/W5W445 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36455 ^@ http://purl.uniprot.org/uniprot/W5WJN3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS09855 ^@ http://purl.uniprot.org/uniprot/W5W3F2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1449976:KALB_RS38690 ^@ http://purl.uniprot.org/uniprot/W5WJ56 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1449976:KALB_RS42390 ^@ http://purl.uniprot.org/uniprot/W5WL80 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1449976:KALB_RS36615 ^@ http://purl.uniprot.org/uniprot/W5WHY3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS38460 ^@ http://purl.uniprot.org/uniprot/W5WK17 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS35220 ^@ http://purl.uniprot.org/uniprot/W5WIF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.|||Membrane http://togogenome.org/gene/1449976:KALB_RS38995 ^@ http://purl.uniprot.org/uniprot/W5WKK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS34135 ^@ http://purl.uniprot.org/uniprot/W5WI93 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1449976:KALB_RS01725 ^@ http://purl.uniprot.org/uniprot/W5VYT7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/1449976:KALB_RS42905 ^@ http://purl.uniprot.org/uniprot/W5WV92 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS18100 ^@ http://purl.uniprot.org/uniprot/W5W781 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1449976:KALB_RS21120 ^@ http://purl.uniprot.org/uniprot/W5WA90 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS43735 ^@ http://purl.uniprot.org/uniprot/W5W3Z6 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/1449976:KALB_RS15930 ^@ http://purl.uniprot.org/uniprot/W5WEH7 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1449976:KALB_RS34585 ^@ http://purl.uniprot.org/uniprot/W5WQE4 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1449976:KALB_RS13095 ^@ http://purl.uniprot.org/uniprot/W5W449 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS25770 ^@ http://purl.uniprot.org/uniprot/W5WDD3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS35000 ^@ http://purl.uniprot.org/uniprot/W5WIA8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1449976:KALB_RS13385 ^@ http://purl.uniprot.org/uniprot/W5W5M0 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1449976:KALB_RS43045 ^@ http://purl.uniprot.org/uniprot/W5WLK0 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1449976:KALB_RS08505 ^@ http://purl.uniprot.org/uniprot/W5WA64 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS07410 ^@ http://purl.uniprot.org/uniprot/W5W116 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1449976:KALB_RS17530 ^@ http://purl.uniprot.org/uniprot/W5W834 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS11150 ^@ http://purl.uniprot.org/uniprot/W5W4F2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/1449976:KALB_RS01895 ^@ http://purl.uniprot.org/uniprot/W5VZ69 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS38985 ^@ http://purl.uniprot.org/uniprot/W5WJA9 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1449976:KALB_RS15020 ^@ http://purl.uniprot.org/uniprot/W5W654 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1449976:KALB_RS16915 ^@ http://purl.uniprot.org/uniprot/W5WF41 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS16935 ^@ http://purl.uniprot.org/uniprot/W5W6G1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS07315 ^@ http://purl.uniprot.org/uniprot/W5W9H9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1449976:KALB_RS18240 ^@ http://purl.uniprot.org/uniprot/W5W8G8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1449976:KALB_RS32995 ^@ http://purl.uniprot.org/uniprot/W5WHI8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1449976:KALB_RS04765 ^@ http://purl.uniprot.org/uniprot/W5W7Y6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1449976:KALB_RS14030 ^@ http://purl.uniprot.org/uniprot/W5W6S9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS13025 ^@ http://purl.uniprot.org/uniprot/W5WCQ2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1449976:KALB_RS02530 ^@ http://purl.uniprot.org/uniprot/W5VYB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1449976:KALB_RS09610 ^@ http://purl.uniprot.org/uniprot/W5W393 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1449976:KALB_RS02220 ^@ http://purl.uniprot.org/uniprot/W5W6J8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS00020 ^@ http://purl.uniprot.org/uniprot/W5VYJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1449976:KALB_RS00420 ^@ http://purl.uniprot.org/uniprot/W5VYS8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1449976:KALB_RS12605 ^@ http://purl.uniprot.org/uniprot/W5WCH8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1449976:KALB_RS00030 ^@ http://purl.uniprot.org/uniprot/W5VX21 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1449976:KALB_RS01100 ^@ http://purl.uniprot.org/uniprot/W5VXL6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS03045 ^@ http://purl.uniprot.org/uniprot/W5W092 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1449976:KALB_RS40990 ^@ http://purl.uniprot.org/uniprot/W5WLI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS20520 ^@ http://purl.uniprot.org/uniprot/W5W9S5 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1449976:KALB_RS28220 ^@ http://purl.uniprot.org/uniprot/W5WEA8 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS10050 ^@ http://purl.uniprot.org/uniprot/W5W3J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS04725 ^@ http://purl.uniprot.org/uniprot/W5W1B5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS12140 ^@ http://purl.uniprot.org/uniprot/W5W4Y2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1449976:KALB_RS18440 ^@ http://purl.uniprot.org/uniprot/W5W946 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1449976:KALB_RS03735 ^@ http://purl.uniprot.org/uniprot/W5VYZ4 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1449976:KALB_RS05320 ^@ http://purl.uniprot.org/uniprot/W5W894 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS39220 ^@ http://purl.uniprot.org/uniprot/W5WLA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS13910 ^@ http://purl.uniprot.org/uniprot/W5W5M3 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS32645 ^@ http://purl.uniprot.org/uniprot/W5WP89 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS20120 ^@ http://purl.uniprot.org/uniprot/W5W902 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1449976:KALB_RS32165 ^@ http://purl.uniprot.org/uniprot/W5WP03 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/1449976:KALB_RS36110 ^@ http://purl.uniprot.org/uniprot/W5WRC3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS33810 ^@ http://purl.uniprot.org/uniprot/W5WGB8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/1449976:KALB_RS00340 ^@ http://purl.uniprot.org/uniprot/W5VYD0 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1449976:KALB_RS47850 ^@ http://purl.uniprot.org/uniprot/W5WN23 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1449976:KALB_RS36720 ^@ http://purl.uniprot.org/uniprot/W5WRM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS18805 ^@ http://purl.uniprot.org/uniprot/W5W8W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1449976:KALB_RS34635 ^@ http://purl.uniprot.org/uniprot/W5WQF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS04815 ^@ http://purl.uniprot.org/uniprot/W5W0N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS25150 ^@ http://purl.uniprot.org/uniprot/W5WCI3 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1449976:KALB_RS00505 ^@ http://purl.uniprot.org/uniprot/W5VY31 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS08690 ^@ http://purl.uniprot.org/uniprot/W5W2Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08015 ^@ http://purl.uniprot.org/uniprot/W5W1D7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1449976:KALB_RS27555 ^@ http://purl.uniprot.org/uniprot/W5WDX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS34815 ^@ http://purl.uniprot.org/uniprot/W5WI65 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1449976:KALB_RS08220 ^@ http://purl.uniprot.org/uniprot/W5WA06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS39485 ^@ http://purl.uniprot.org/uniprot/W5WTA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1449976:KALB_RS09440 ^@ http://purl.uniprot.org/uniprot/W5W294 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS40775 ^@ http://purl.uniprot.org/uniprot/W5WU44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1449976:KALB_RS10975 ^@ http://purl.uniprot.org/uniprot/W5W558 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS40325 ^@ http://purl.uniprot.org/uniprot/W5WLB5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1449976:KALB_RS15415 ^@ http://purl.uniprot.org/uniprot/W5WGT0 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1449976:KALB_RS08425 ^@ http://purl.uniprot.org/uniprot/W5W1L4 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1449976:KALB_RS14620 ^@ http://purl.uniprot.org/uniprot/W5W712 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. EgtD family.|||Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS29215 ^@ http://purl.uniprot.org/uniprot/W5WFE4 ^@ Similarity ^@ Belongs to the peptidase S15 family. http://togogenome.org/gene/1449976:KALB_RS12455 ^@ http://purl.uniprot.org/uniprot/W5WCF0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1449976:KALB_RS40305 ^@ http://purl.uniprot.org/uniprot/W5WLX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1449976:KALB_RS27475 ^@ http://purl.uniprot.org/uniprot/W5WLA4 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1449976:KALB_RS42395 ^@ http://purl.uniprot.org/uniprot/W5WUY8 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1449976:KALB_RS04860 ^@ http://purl.uniprot.org/uniprot/W5W804 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1449976:KALB_RS11815 ^@ http://purl.uniprot.org/uniprot/W5WC36 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS07930 ^@ http://purl.uniprot.org/uniprot/W5W3A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS30800 ^@ http://purl.uniprot.org/uniprot/W5WFP3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1449976:KALB_RS36600 ^@ http://purl.uniprot.org/uniprot/W5WJ85 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1449976:KALB_RS43775 ^@ http://purl.uniprot.org/uniprot/W5W4S9 ^@ Similarity ^@ Belongs to the EspG family. http://togogenome.org/gene/1449976:KALB_RS22770 ^@ http://purl.uniprot.org/uniprot/W5WA17 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS41740 ^@ http://purl.uniprot.org/uniprot/W5WM38 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS05000 ^@ http://purl.uniprot.org/uniprot/W5W0R7 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/1449976:KALB_RS36885 ^@ http://purl.uniprot.org/uniprot/W5WI44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS40285 ^@ http://purl.uniprot.org/uniprot/W5WL28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1449976:KALB_RS37085 ^@ http://purl.uniprot.org/uniprot/W5WRV5 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1449976:KALB_RS13455 ^@ http://purl.uniprot.org/uniprot/W5W5N9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1449976:KALB_RS13745 ^@ http://purl.uniprot.org/uniprot/W5WD85 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1449976:KALB_RS42835 ^@ http://purl.uniprot.org/uniprot/W5WV75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS36675 ^@ http://purl.uniprot.org/uniprot/W5WJA0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS39900 ^@ http://purl.uniprot.org/uniprot/W5WL31 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS40395 ^@ http://purl.uniprot.org/uniprot/W5WTT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1449976:KALB_RS13310 ^@ http://purl.uniprot.org/uniprot/W5W6C4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS30130 ^@ http://purl.uniprot.org/uniprot/W5WF67 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1449976:KALB_RS28485 ^@ http://purl.uniprot.org/uniprot/W5WDD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily.|||Periplasm http://togogenome.org/gene/1449976:KALB_RS27985 ^@ http://purl.uniprot.org/uniprot/W5WEM5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1449976:KALB_RS37495 ^@ http://purl.uniprot.org/uniprot/W5WJD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1449976:KALB_RS34900 ^@ http://purl.uniprot.org/uniprot/W5WHW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1449976:KALB_RS01570 ^@ http://purl.uniprot.org/uniprot/W5VZJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1B family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS22120 ^@ http://purl.uniprot.org/uniprot/W5WBD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1449976:KALB_RS42575 ^@ http://purl.uniprot.org/uniprot/W5WML0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1449976:KALB_RS49880 ^@ http://purl.uniprot.org/uniprot/W5W9I2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS04610 ^@ http://purl.uniprot.org/uniprot/W5W0E7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MshB deacetylase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. http://togogenome.org/gene/1449976:KALB_RS24005 ^@ http://purl.uniprot.org/uniprot/W5WCH3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS36835 ^@ http://purl.uniprot.org/uniprot/W5WJ01 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS29645 ^@ http://purl.uniprot.org/uniprot/W5WFM1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1449976:KALB_RS10580 ^@ http://purl.uniprot.org/uniprot/W5W3U3 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1449976:KALB_RS37410 ^@ http://purl.uniprot.org/uniprot/W5WJP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1449976:KALB_RS34415 ^@ http://purl.uniprot.org/uniprot/W5WGN8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS35320 ^@ http://purl.uniprot.org/uniprot/W5WIW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1449976:KALB_RS14155 ^@ http://purl.uniprot.org/uniprot/W5W6U4 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1449976:KALB_RS28925 ^@ http://purl.uniprot.org/uniprot/W5WEH9 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/1449976:KALB_RS01160 ^@ http://purl.uniprot.org/uniprot/W5W5Y1 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/1449976:KALB_RS04435 ^@ http://purl.uniprot.org/uniprot/W5W162 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1449976:KALB_RS15615 ^@ http://purl.uniprot.org/uniprot/W5W6I5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1449976:KALB_RS00700 ^@ http://purl.uniprot.org/uniprot/W5VYY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS30400 ^@ http://purl.uniprot.org/uniprot/W5WFL5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1449976:KALB_RS33365 ^@ http://purl.uniprot.org/uniprot/W5WH46 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS01825 ^@ http://purl.uniprot.org/uniprot/W5VZN9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1449976:KALB_RS02970 ^@ http://purl.uniprot.org/uniprot/W5W076 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1449976:KALB_RS07280 ^@ http://purl.uniprot.org/uniprot/W5W1V8 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/1449976:KALB_RS20530 ^@ http://purl.uniprot.org/uniprot/W5W981 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/1449976:KALB_RS19665 ^@ http://purl.uniprot.org/uniprot/W5W8S8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS15085 ^@ http://purl.uniprot.org/uniprot/W5W6L8 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/1449976:KALB_RS35245 ^@ http://purl.uniprot.org/uniprot/W5WIV1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1449976:KALB_RS03430 ^@ http://purl.uniprot.org/uniprot/W5VZQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS38975 ^@ http://purl.uniprot.org/uniprot/W5WL58 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1449976:KALB_RS21290 ^@ http://purl.uniprot.org/uniprot/W5WAB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS11920 ^@ http://purl.uniprot.org/uniprot/W5W4T0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42365 ^@ http://purl.uniprot.org/uniprot/W5WL75 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS38025 ^@ http://purl.uniprot.org/uniprot/W5WIR2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS03890 ^@ http://purl.uniprot.org/uniprot/W5W7I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS09090 ^@ http://purl.uniprot.org/uniprot/W5W437 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1449976:KALB_RS40360 ^@ http://purl.uniprot.org/uniprot/W5WL45 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1449976:KALB_RS30390 ^@ http://purl.uniprot.org/uniprot/W5WEC8 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/1449976:KALB_RS19490 ^@ http://purl.uniprot.org/uniprot/W5W8Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS23290 ^@ http://purl.uniprot.org/uniprot/W5WAX6 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1449976:KALB_RS20090 ^@ http://purl.uniprot.org/uniprot/W5WGY4 ^@ Similarity ^@ Belongs to the AHA1 family.|||Belongs to the UPF0098 family. http://togogenome.org/gene/1449976:KALB_RS21610 ^@ http://purl.uniprot.org/uniprot/W5WHV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS42195 ^@ http://purl.uniprot.org/uniprot/W5WUU6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS40565 ^@ http://purl.uniprot.org/uniprot/W5WTX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1449976:KALB_RS30440 ^@ http://purl.uniprot.org/uniprot/W5WED6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS18800 ^@ http://purl.uniprot.org/uniprot/W5WG83 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS08945 ^@ http://purl.uniprot.org/uniprot/W5W2X1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1449976:KALB_RS25555 ^@ http://purl.uniprot.org/uniprot/W5WD84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36180 ^@ http://purl.uniprot.org/uniprot/W5WHQ6 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/1449976:KALB_RS28010 ^@ http://purl.uniprot.org/uniprot/W5WEM9 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1449976:KALB_RS29550 ^@ http://purl.uniprot.org/uniprot/W5WEV0 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1449976:KALB_RS03980 ^@ http://purl.uniprot.org/uniprot/W5W0X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1449976:KALB_RS32225 ^@ http://purl.uniprot.org/uniprot/W5WH41 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1449976:KALB_RS04665 ^@ http://purl.uniprot.org/uniprot/W5W7W7 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1449976:KALB_RS32950 ^@ http://purl.uniprot.org/uniprot/W5WGT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS12405 ^@ http://purl.uniprot.org/uniprot/W5WCE1 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1449976:KALB_RS10455 ^@ http://purl.uniprot.org/uniprot/W5W4U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS36080 ^@ http://purl.uniprot.org/uniprot/W5WHP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1449976:KALB_RS01055 ^@ http://purl.uniprot.org/uniprot/W5W5W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS04075 ^@ http://purl.uniprot.org/uniprot/W5W0A2 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/1449976:KALB_RS30065 ^@ http://purl.uniprot.org/uniprot/W5WMS1 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1449976:KALB_RS35675 ^@ http://purl.uniprot.org/uniprot/W5WIG9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS38015 ^@ http://purl.uniprot.org/uniprot/W5WKJ9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1449976:KALB_RS00500 ^@ http://purl.uniprot.org/uniprot/W5VYU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS10230 ^@ http://purl.uniprot.org/uniprot/W5W2N6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/1449976:KALB_RS23260 ^@ http://purl.uniprot.org/uniprot/W5WC08 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1449976:KALB_RS42275 ^@ http://purl.uniprot.org/uniprot/W5WME3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1449976:KALB_RS33130 ^@ http://purl.uniprot.org/uniprot/W5WFW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-binding monooxygenase family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/1449976:KALB_RS42230 ^@ http://purl.uniprot.org/uniprot/W5WN08 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1449976:KALB_RS40320 ^@ http://purl.uniprot.org/uniprot/W5WTS3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS04565 ^@ http://purl.uniprot.org/uniprot/W5VZE8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1449976:KALB_RS40960 ^@ http://purl.uniprot.org/uniprot/W5WME1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS10290 ^@ http://purl.uniprot.org/uniprot/W5W3U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1449976:KALB_RS01815 ^@ http://purl.uniprot.org/uniprot/W5W6C7 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1449976:KALB_RS03860 ^@ http://purl.uniprot.org/uniprot/W5VZ22 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS16290 ^@ http://purl.uniprot.org/uniprot/W5W813 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1449976:KALB_RS35070 ^@ http://purl.uniprot.org/uniprot/W5WIC4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1449976:KALB_RS33790 ^@ http://purl.uniprot.org/uniprot/W5WPZ4 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1449976:KALB_RS34530 ^@ http://purl.uniprot.org/uniprot/W5WHP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1449976:KALB_RS13535 ^@ http://purl.uniprot.org/uniprot/W5W5C8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1449976:KALB_RS05425 ^@ http://purl.uniprot.org/uniprot/W5VZW3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1449976:KALB_RS33745 ^@ http://purl.uniprot.org/uniprot/W5WHK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS20665 ^@ http://purl.uniprot.org/uniprot/W5W8S7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1449976:KALB_RS38020 ^@ http://purl.uniprot.org/uniprot/W5WJP9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/1449976:KALB_RS37395 ^@ http://purl.uniprot.org/uniprot/W5WJB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1449976:KALB_RS39890 ^@ http://purl.uniprot.org/uniprot/W5WKS6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1449976:KALB_RS39570 ^@ http://purl.uniprot.org/uniprot/W5WLG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS08405 ^@ http://purl.uniprot.org/uniprot/W5WA44 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1449976:KALB_RS04690 ^@ http://purl.uniprot.org/uniprot/W5W7X2 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1449976:KALB_RS27265 ^@ http://purl.uniprot.org/uniprot/W5WL61 ^@ Similarity ^@ Belongs to the peptidase M7 family. http://togogenome.org/gene/1449976:KALB_RS10355 ^@ http://purl.uniprot.org/uniprot/W5W3Q6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS02080 ^@ http://purl.uniprot.org/uniprot/W5VYY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS04455 ^@ http://purl.uniprot.org/uniprot/W5W0G6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1449976:KALB_RS08995 ^@ http://purl.uniprot.org/uniprot/W5W2X9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1449976:KALB_RS08660 ^@ http://purl.uniprot.org/uniprot/W5WAD2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1449976:KALB_RS40790 ^@ http://purl.uniprot.org/uniprot/W5WLG1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1449976:KALB_RS37525 ^@ http://purl.uniprot.org/uniprot/W5WIG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS12915 ^@ http://purl.uniprot.org/uniprot/W5WCN1 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/1449976:KALB_RS07355 ^@ http://purl.uniprot.org/uniprot/W5W1X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS15325 ^@ http://purl.uniprot.org/uniprot/W5W6S0 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/1449976:KALB_RS13290 ^@ http://purl.uniprot.org/uniprot/W5W580 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1449976:KALB_RS35310 ^@ http://purl.uniprot.org/uniprot/W5WQT9 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1449976:KALB_RS10760 ^@ http://purl.uniprot.org/uniprot/W5W2Y0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1449976:KALB_RS34955 ^@ http://purl.uniprot.org/uniprot/W5WQL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1449976:KALB_RS06560 ^@ http://purl.uniprot.org/uniprot/W5W943 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1449976:KALB_RS35390 ^@ http://purl.uniprot.org/uniprot/W5WII9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1449976:KALB_RS31460 ^@ http://purl.uniprot.org/uniprot/W5WEX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS32575 ^@ http://purl.uniprot.org/uniprot/W5WGW0 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1449976:KALB_RS40375 ^@ http://purl.uniprot.org/uniprot/W5WLC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1449976:KALB_RS01540 ^@ http://purl.uniprot.org/uniprot/W5VZ16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS40405 ^@ http://purl.uniprot.org/uniprot/W5WLZ3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1449976:KALB_RS37295 ^@ http://purl.uniprot.org/uniprot/W5WJ92 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1449976:KALB_RS31185 ^@ http://purl.uniprot.org/uniprot/W5WG37 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Has an organic peroxide-dependent peroxidase activity. http://togogenome.org/gene/1449976:KALB_RS38605 ^@ http://purl.uniprot.org/uniprot/W5WKZ4 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. http://togogenome.org/gene/1449976:KALB_RS08700 ^@ http://purl.uniprot.org/uniprot/W5W2T2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1449976:KALB_RS24880 ^@ http://purl.uniprot.org/uniprot/W5WCC2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1449976:KALB_RS05535 ^@ http://purl.uniprot.org/uniprot/W5W121 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1449976:KALB_RS32815 ^@ http://purl.uniprot.org/uniprot/W5WH10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS16940 ^@ http://purl.uniprot.org/uniprot/W5WF45 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS40410 ^@ http://purl.uniprot.org/uniprot/W5WL55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1449976:KALB_RS13765 ^@ http://purl.uniprot.org/uniprot/W5W4K2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1449976:KALB_RS03050 ^@ http://purl.uniprot.org/uniprot/W5VZH4 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1449976:KALB_RS28835 ^@ http://purl.uniprot.org/uniprot/W5WM45 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS29830 ^@ http://purl.uniprot.org/uniprot/W5WE23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS08275 ^@ http://purl.uniprot.org/uniprot/W5W3I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS10920 ^@ http://purl.uniprot.org/uniprot/W5W471 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS05665 ^@ http://purl.uniprot.org/uniprot/W5W1T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS05880 ^@ http://purl.uniprot.org/uniprot/W5W041 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1449976:KALB_RS22960 ^@ http://purl.uniprot.org/uniprot/W5WBT2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1449976:KALB_RS03025 ^@ http://purl.uniprot.org/uniprot/W5VZG9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS13575 ^@ http://purl.uniprot.org/uniprot/W5W5R8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1449976:KALB_RS40025 ^@ http://purl.uniprot.org/uniprot/W5WL56 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS15820 ^@ http://purl.uniprot.org/uniprot/W5W6M7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1449976:KALB_RS03145 ^@ http://purl.uniprot.org/uniprot/W5W0A9 ^@ Similarity ^@ Belongs to the DNA photolyase family. http://togogenome.org/gene/1449976:KALB_RS23560 ^@ http://purl.uniprot.org/uniprot/W5WAK5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS14610 ^@ http://purl.uniprot.org/uniprot/W5WDQ1 ^@ Function|||Similarity ^@ Belongs to the EgtB family.|||Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/1449976:KALB_RS36935 ^@ http://purl.uniprot.org/uniprot/W5WI57 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1449976:KALB_RS25165 ^@ http://purl.uniprot.org/uniprot/W5WBC2 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1449976:KALB_RS02145 ^@ http://purl.uniprot.org/uniprot/W5VZA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1449976:KALB_RS37390 ^@ http://purl.uniprot.org/uniprot/W5WK61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1449976:KALB_RS09860 ^@ http://purl.uniprot.org/uniprot/W5W2G2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1449976:KALB_RS15310 ^@ http://purl.uniprot.org/uniprot/W5W6C1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1449976:KALB_RS03730 ^@ http://purl.uniprot.org/uniprot/W5W003 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1449976:KALB_RS34945 ^@ http://purl.uniprot.org/uniprot/W5WHY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1449976:KALB_RS25390 ^@ http://purl.uniprot.org/uniprot/W5WK09 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1449976:KALB_RS40435 ^@ http://purl.uniprot.org/uniprot/W5WL60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1449976:KALB_RS40195 ^@ http://purl.uniprot.org/uniprot/W5WTP8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1449976:KALB_RS02070 ^@ http://purl.uniprot.org/uniprot/W5VZ98 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1449976:KALB_RS13650 ^@ http://purl.uniprot.org/uniprot/W5W5W7 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1449976:KALB_RS13890 ^@ http://purl.uniprot.org/uniprot/W5W4M4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/1449976:KALB_RS06495 ^@ http://purl.uniprot.org/uniprot/W5W2H4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1449976:KALB_RS05155 ^@ http://purl.uniprot.org/uniprot/W5W1I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1449976:KALB_RS08350 ^@ http://purl.uniprot.org/uniprot/W5W1J4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1449976:KALB_RS11365 ^@ http://purl.uniprot.org/uniprot/W5W3A9 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/1449976:KALB_RS13665 ^@ http://purl.uniprot.org/uniprot/W5W4I3 ^@ Similarity ^@ Belongs to the guanylate kinase family.