http://togogenome.org/gene/172713:B4V02_RS17770 ^@ http://purl.uniprot.org/uniprot/A0A222WQZ0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS21245 ^@ http://purl.uniprot.org/uniprot/A0A222WTJ5 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/172713:B4V02_RS22885 ^@ http://purl.uniprot.org/uniprot/A0A222WS41 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/172713:B4V02_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A222WMG2 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/172713:B4V02_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A222WL54 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/172713:B4V02_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A222WI96 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A222WKF6 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/172713:B4V02_RS22460 ^@ http://purl.uniprot.org/uniprot/A0A222WRR1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/172713:B4V02_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A222WKI7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/172713:B4V02_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A222WMT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A222WI12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A222WVK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/172713:B4V02_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A222WMP2 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/172713:B4V02_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A222WGX7 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/172713:B4V02_RS13485 ^@ http://purl.uniprot.org/uniprot/A0A222WNB7 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/172713:B4V02_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A222WKJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/172713:B4V02_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A222WLU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/172713:B4V02_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A222WI32 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/172713:B4V02_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A222WQJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/172713:B4V02_RS15415 ^@ http://purl.uniprot.org/uniprot/A0A222WPZ9 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/172713:B4V02_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A222WKJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS15025 ^@ http://purl.uniprot.org/uniprot/A0A222WN60 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.|||Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/172713:B4V02_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A222WID3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/172713:B4V02_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A222WS08 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A222WMU8 ^@ Similarity ^@ Belongs to the cycloisomerase 2 family. http://togogenome.org/gene/172713:B4V02_RS16920 ^@ http://purl.uniprot.org/uniprot/A0A222WR51 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/172713:B4V02_RS14965 ^@ http://purl.uniprot.org/uniprot/A0A222WPF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/172713:B4V02_RS15160 ^@ http://purl.uniprot.org/uniprot/A0A222WPG9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A222WRL6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/172713:B4V02_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A222WRW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A222WIP4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS17815 ^@ http://purl.uniprot.org/uniprot/A0A222WQI6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/172713:B4V02_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A222WI05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/172713:B4V02_RS17775 ^@ http://purl.uniprot.org/uniprot/A0A222WPK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/172713:B4V02_RS15435 ^@ http://purl.uniprot.org/uniprot/A0A222WPQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/172713:B4V02_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A222WKZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS18910 ^@ http://purl.uniprot.org/uniprot/A0A222WRI6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/172713:B4V02_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A222WKF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A222WIP0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/172713:B4V02_RS24510 ^@ http://purl.uniprot.org/uniprot/A0A222WUZ6 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/172713:B4V02_RS25050 ^@ http://purl.uniprot.org/uniprot/A0A222WV90 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/172713:B4V02_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A222WTH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/172713:B4V02_RS24320 ^@ http://purl.uniprot.org/uniprot/A0A222WSK5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/172713:B4V02_RS15120 ^@ http://purl.uniprot.org/uniprot/A0A222WN53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/172713:B4V02_RS18835 ^@ http://purl.uniprot.org/uniprot/A0A222WRH6 ^@ Similarity ^@ Belongs to the GbsR family. http://togogenome.org/gene/172713:B4V02_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A222WIT0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/172713:B4V02_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A222WM48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/172713:B4V02_RS24335 ^@ http://purl.uniprot.org/uniprot/A0A222WUD8 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/172713:B4V02_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A222WIZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/172713:B4V02_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A222WHL0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A222WFT0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A222WPF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/172713:B4V02_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A222WIE4 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/172713:B4V02_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A222WGW8 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/172713:B4V02_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A222WJV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/172713:B4V02_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A222WJX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/172713:B4V02_RS21400 ^@ http://purl.uniprot.org/uniprot/A0A222WSW1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/172713:B4V02_RS15320 ^@ http://purl.uniprot.org/uniprot/A0A222WPB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A222WHB4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/172713:B4V02_RS24565 ^@ http://purl.uniprot.org/uniprot/A0A222WV11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RpoE family.|||Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors. http://togogenome.org/gene/172713:B4V02_RS20045 ^@ http://purl.uniprot.org/uniprot/A0A222WS26 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/172713:B4V02_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A222WJZ3 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/172713:B4V02_RS25265 ^@ http://purl.uniprot.org/uniprot/A0A222WT10 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/172713:B4V02_RS18995 ^@ http://purl.uniprot.org/uniprot/A0A222WRK1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/172713:B4V02_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A222WKD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/172713:B4V02_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A222WH86 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/172713:B4V02_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A222WKY3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/172713:B4V02_RS15325 ^@ http://purl.uniprot.org/uniprot/A0A222WN90 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A222WIX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/172713:B4V02_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A222WNZ5 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A222WUN8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/172713:B4V02_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A222WR41 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/172713:B4V02_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A222WTF0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/172713:B4V02_RS25255 ^@ http://purl.uniprot.org/uniprot/A0A222WTA5 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/172713:B4V02_RS22115 ^@ http://purl.uniprot.org/uniprot/A0A222WT97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS25225 ^@ http://purl.uniprot.org/uniprot/A0A222WVD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/172713:B4V02_RS17065 ^@ http://purl.uniprot.org/uniprot/A0A222WP38 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A222WGX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/172713:B4V02_RS25215 ^@ http://purl.uniprot.org/uniprot/A0A222WVL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/172713:B4V02_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A222WJ04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/172713:B4V02_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A222WIZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/172713:B4V02_RS24775 ^@ http://purl.uniprot.org/uniprot/A0A222WV42 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/172713:B4V02_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A222WMC5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/172713:B4V02_RS25335 ^@ http://purl.uniprot.org/uniprot/A0A222WUV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A222WQA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS20990 ^@ http://purl.uniprot.org/uniprot/A0A222WS25 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/172713:B4V02_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A222WHD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A222WLK6 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/172713:B4V02_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A222WL61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS16165 ^@ http://purl.uniprot.org/uniprot/A0A222WQ26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A222WKP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/172713:B4V02_RS21225 ^@ http://purl.uniprot.org/uniprot/A0A222WR33 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/172713:B4V02_RS20070 ^@ http://purl.uniprot.org/uniprot/A0A222WQF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A222WIC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS11505 ^@ http://purl.uniprot.org/uniprot/A0A222WLD1 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/172713:B4V02_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A222WFW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS20420 ^@ http://purl.uniprot.org/uniprot/A0A222WSL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A222WKQ8 ^@ Similarity|||Subunit ^@ Belongs to the MtrB family.|||Oligomer of 11 identical subunits arranged in doughnut-like structure. http://togogenome.org/gene/172713:B4V02_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A222WPG3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/172713:B4V02_RS21515 ^@ http://purl.uniprot.org/uniprot/A0A222WTK0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/172713:B4V02_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A222WM63 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/172713:B4V02_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A222WL85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS22010 ^@ http://purl.uniprot.org/uniprot/A0A222WTH3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/172713:B4V02_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A222WPK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane http://togogenome.org/gene/172713:B4V02_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A222WKH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/172713:B4V02_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A222WPX6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/172713:B4V02_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A222WH63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/172713:B4V02_RS24330 ^@ http://purl.uniprot.org/uniprot/A0A222WUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/172713:B4V02_RS24700 ^@ http://purl.uniprot.org/uniprot/A0A222WSZ1 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/172713:B4V02_RS15255 ^@ http://purl.uniprot.org/uniprot/A0A222WQA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/172713:B4V02_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A222WIS7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/172713:B4V02_RS21445 ^@ http://purl.uniprot.org/uniprot/A0A222WR54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A222WL83 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS24710 ^@ http://purl.uniprot.org/uniprot/A0A222WSR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A222WQG4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A222WIC5 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/172713:B4V02_RS21505 ^@ http://purl.uniprot.org/uniprot/A0A222WR84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0154 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A222WI94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/172713:B4V02_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A222WKY5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/172713:B4V02_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A222WHD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/172713:B4V02_RS11625 ^@ http://purl.uniprot.org/uniprot/A0A222WLD2 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/172713:B4V02_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A222WI95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A222WIJ0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/172713:B4V02_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A222WQN2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/172713:B4V02_RS20075 ^@ http://purl.uniprot.org/uniprot/A0A222WSV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS21975 ^@ http://purl.uniprot.org/uniprot/A0A222WRF0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/172713:B4V02_RS10690 ^@ http://purl.uniprot.org/uniprot/A0A222WN00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/172713:B4V02_RS23935 ^@ http://purl.uniprot.org/uniprot/A0A222WS77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A222WPB8 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/172713:B4V02_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A222WLP9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A222WHX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS17695 ^@ http://purl.uniprot.org/uniprot/A0A222WQH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A222WKT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/172713:B4V02_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A222WQH9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A222WHD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/172713:B4V02_RS06540 ^@ http://purl.uniprot.org/uniprot/A0A222WKR6 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/172713:B4V02_RS25030 ^@ http://purl.uniprot.org/uniprot/A0A222WUK7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/172713:B4V02_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A222WPV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/172713:B4V02_RS15445 ^@ http://purl.uniprot.org/uniprot/A0A222WN72 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/172713:B4V02_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A222WKU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A222WPJ9 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/172713:B4V02_RS15370 ^@ http://purl.uniprot.org/uniprot/A0A222WPL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A222WH62 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/172713:B4V02_RS02995 ^@ http://purl.uniprot.org/uniprot/A0A222WIY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/172713:B4V02_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A222WKS9 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/172713:B4V02_RS25520 ^@ http://purl.uniprot.org/uniprot/A0A222WUI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/172713:B4V02_RS23360 ^@ http://purl.uniprot.org/uniprot/A0A222WS36 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/172713:B4V02_RS17720 ^@ http://purl.uniprot.org/uniprot/A0A222WVJ9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/172713:B4V02_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A222WKE7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A222WM53 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/172713:B4V02_RS24270 ^@ http://purl.uniprot.org/uniprot/A0A222WUY3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/172713:B4V02_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A222WI63 ^@ Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family. http://togogenome.org/gene/172713:B4V02_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A222WKW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/172713:B4V02_RS14425 ^@ http://purl.uniprot.org/uniprot/A0A222WPP9 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/172713:B4V02_RS17045 ^@ http://purl.uniprot.org/uniprot/A0A222WRC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/172713:B4V02_RS25055 ^@ http://purl.uniprot.org/uniprot/A0A222WUQ8 ^@ Similarity ^@ Belongs to the alpha/beta-type SASP family. http://togogenome.org/gene/172713:B4V02_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A222WH77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS20305 ^@ http://purl.uniprot.org/uniprot/A0A222WSK0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS24325 ^@ http://purl.uniprot.org/uniprot/A0A222WSH7 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/172713:B4V02_RS22745 ^@ http://purl.uniprot.org/uniprot/A0A222WRR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family. BdbC subfamily.|||Membrane http://togogenome.org/gene/172713:B4V02_RS15385 ^@ http://purl.uniprot.org/uniprot/A0A222WPP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/172713:B4V02_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A222WKI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A222WMP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A222WHL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A222WHZ2 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/172713:B4V02_RS15970 ^@ http://purl.uniprot.org/uniprot/A0A222WNP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS16650 ^@ http://purl.uniprot.org/uniprot/A0A222WQT4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A222WKS0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/172713:B4V02_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A222WI08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS08675 ^@ http://purl.uniprot.org/uniprot/A0A222WJU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/172713:B4V02_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A222WIB3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A222WIR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A222WI64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/172713:B4V02_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A222WLV9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS24930 ^@ http://purl.uniprot.org/uniprot/A0A222WST7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/172713:B4V02_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A222WQG1 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/172713:B4V02_RS24255 ^@ http://purl.uniprot.org/uniprot/A0A222WU86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/172713:B4V02_RS24380 ^@ http://purl.uniprot.org/uniprot/A0A222WTV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A222WQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/172713:B4V02_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A222WPW9 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/172713:B4V02_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A222WHB7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A222WJG1 ^@ PTM|||Subcellular Location Annotation ^@ Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS22450 ^@ http://purl.uniprot.org/uniprot/A0A222WRT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A222WLW4 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/172713:B4V02_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A222WGS0 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/172713:B4V02_RS22015 ^@ http://purl.uniprot.org/uniprot/A0A222WT75 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/172713:B4V02_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A222WL36 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/172713:B4V02_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A222WI13 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/172713:B4V02_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A222WFT3 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/172713:B4V02_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A222WGT2 ^@ Similarity ^@ Belongs to the HPS/KGPDC family. HPS subfamily. http://togogenome.org/gene/172713:B4V02_RS25220 ^@ http://purl.uniprot.org/uniprot/A0A222WT09 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/172713:B4V02_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A222WHZ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/172713:B4V02_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A222WMA4 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/172713:B4V02_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A222WPR7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A222WK91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A222WJ22 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/172713:B4V02_RS15295 ^@ http://purl.uniprot.org/uniprot/A0A222WQA9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/172713:B4V02_RS21015 ^@ http://purl.uniprot.org/uniprot/A0A222WTA8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/172713:B4V02_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A222WJP4 ^@ Activity Regulation|||Function|||PTM|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme. http://togogenome.org/gene/172713:B4V02_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A222WL82 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/172713:B4V02_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A222WL46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A222WJL9 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/172713:B4V02_RS15410 ^@ http://purl.uniprot.org/uniprot/A0A222WQD9 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/172713:B4V02_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A222WH80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/172713:B4V02_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A222WMR4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/172713:B4V02_RS22755 ^@ http://purl.uniprot.org/uniprot/A0A222WTM1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/172713:B4V02_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A222WHQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A222WI87 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/172713:B4V02_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A222WJP9 ^@ Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SspI family.|||Expressed only in the forespore compartment of sporulating cells.|||Spore core http://togogenome.org/gene/172713:B4V02_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A222WJ55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A222WJU2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/172713:B4V02_RS20120 ^@ http://purl.uniprot.org/uniprot/A0A222WQG9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A222WHT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A222WJM3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/172713:B4V02_RS16420 ^@ http://purl.uniprot.org/uniprot/A0A222WQG7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS22355 ^@ http://purl.uniprot.org/uniprot/A0A222WRP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A222WJC9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/172713:B4V02_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A222WL77 ^@ Function ^@ Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. http://togogenome.org/gene/172713:B4V02_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A222WHT7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/172713:B4V02_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A222WTJ8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.|||Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. http://togogenome.org/gene/172713:B4V02_RS24730 ^@ http://purl.uniprot.org/uniprot/A0A222WV33 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS15465 ^@ http://purl.uniprot.org/uniprot/A0A222WQ09 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/172713:B4V02_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A222WHQ3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS14895 ^@ http://purl.uniprot.org/uniprot/A0A222WPL9 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/172713:B4V02_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A222WGP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS25250 ^@ http://purl.uniprot.org/uniprot/A0A222WUC1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 535 of 16S rRNA. http://togogenome.org/gene/172713:B4V02_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A222WL10 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/172713:B4V02_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A222WIB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A222WMX5 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/172713:B4V02_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A222WIW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/172713:B4V02_RS25230 ^@ http://purl.uniprot.org/uniprot/A0A222WUT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.|||Cell membrane|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. http://togogenome.org/gene/172713:B4V02_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A222WMB5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/172713:B4V02_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A222WGJ6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/172713:B4V02_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A222WIU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/172713:B4V02_RS25465 ^@ http://purl.uniprot.org/uniprot/A0A222WUH5 ^@ Function|||Subunit ^@ Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A222WH58 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/172713:B4V02_RS20020 ^@ http://purl.uniprot.org/uniprot/A0A222WQE8 ^@ Similarity ^@ Belongs to the NifX/NifY family. http://togogenome.org/gene/172713:B4V02_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A222WJR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/172713:B4V02_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A222WMJ3 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/172713:B4V02_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A222WH48 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/172713:B4V02_RS10155 ^@ http://purl.uniprot.org/uniprot/A0A222WM15 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/172713:B4V02_RS25380 ^@ http://purl.uniprot.org/uniprot/A0A222WT27 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/172713:B4V02_RS25385 ^@ http://purl.uniprot.org/uniprot/A0A222WT36 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/172713:B4V02_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A222WQC4 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/172713:B4V02_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A222WHH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/172713:B4V02_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A222WGY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A222WJE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS24545 ^@ http://purl.uniprot.org/uniprot/A0A222WSP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS18490 ^@ http://purl.uniprot.org/uniprot/A0A222WPQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS15305 ^@ http://purl.uniprot.org/uniprot/A0A222WQB7 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/172713:B4V02_RS19830 ^@ http://purl.uniprot.org/uniprot/A0A222WRI9 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/172713:B4V02_RS19310 ^@ http://purl.uniprot.org/uniprot/A0A222WQ82 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/172713:B4V02_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A222WFY9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rhamnose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the interconversion of L-rhamnose and L-rhamnulose.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A222WHC4 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/172713:B4V02_RS22095 ^@ http://purl.uniprot.org/uniprot/A0A222WRJ3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS25375 ^@ http://purl.uniprot.org/uniprot/A0A222WUS2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/172713:B4V02_RS22090 ^@ http://purl.uniprot.org/uniprot/A0A222WT96 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A222WIA5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/172713:B4V02_RS25320 ^@ http://purl.uniprot.org/uniprot/A0A222WT18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/172713:B4V02_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A222WQH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/172713:B4V02_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A222WH35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A222WHI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/172713:B4V02_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A222WLG2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Central regulator of manganese homeostasis.|||Cytoplasm|||DNA binding is strongly activated by Mn(2+).|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A222WQE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS16305 ^@ http://purl.uniprot.org/uniprot/A0A222WNN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. CshA subfamily.|||Cytoplasm|||DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.|||Oligomerizes, may be a member of the RNA degradosome. http://togogenome.org/gene/172713:B4V02_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A222WHQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/172713:B4V02_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A222WLQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/172713:B4V02_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A222WI72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/172713:B4V02_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A222WM00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/172713:B4V02_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A222WLI4 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/172713:B4V02_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A222WJ89 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/172713:B4V02_RS25040 ^@ http://purl.uniprot.org/uniprot/A0A222WW99 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/172713:B4V02_RS15075 ^@ http://purl.uniprot.org/uniprot/A0A222WPH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/172713:B4V02_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A222WJX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A222WNU8 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/172713:B4V02_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A222WMS8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A222WL98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A222WK85 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/172713:B4V02_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A222WKM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/172713:B4V02_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A222WIA3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/172713:B4V02_RS14970 ^@ http://purl.uniprot.org/uniprot/A0A222WN49 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/172713:B4V02_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A222WMM5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/172713:B4V02_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A222WN59 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/172713:B4V02_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A222WKG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/172713:B4V02_RS24530 ^@ http://purl.uniprot.org/uniprot/A0A222WTY1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A222WRU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SspH family.|||Spore core http://togogenome.org/gene/172713:B4V02_RS20705 ^@ http://purl.uniprot.org/uniprot/A0A222WSI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A222WGV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/172713:B4V02_RS24285 ^@ http://purl.uniprot.org/uniprot/A0A222WUP2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS20395 ^@ http://purl.uniprot.org/uniprot/A0A222WQL2 ^@ Similarity ^@ Belongs to the CAPAB/TerDEXZ family. http://togogenome.org/gene/172713:B4V02_RS21030 ^@ http://purl.uniprot.org/uniprot/A0A222WSX1 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/172713:B4V02_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A222WQC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/172713:B4V02_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A222WHE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/172713:B4V02_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A222WJ32 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/172713:B4V02_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A222WRG6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A222WNB3 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/172713:B4V02_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A222WLQ2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS16225 ^@ http://purl.uniprot.org/uniprot/A0A222WNP4 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/172713:B4V02_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A222WLA1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/172713:B4V02_RS21010 ^@ http://purl.uniprot.org/uniprot/A0A222WQV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/172713:B4V02_RS24935 ^@ http://purl.uniprot.org/uniprot/A0A222WSV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A222WJK1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/172713:B4V02_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A222WPP1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/172713:B4V02_RS20385 ^@ http://purl.uniprot.org/uniprot/A0A222WSB8 ^@ Similarity ^@ Belongs to the CAPAB/TerDEXZ family. http://togogenome.org/gene/172713:B4V02_RS24875 ^@ http://purl.uniprot.org/uniprot/A0A222WUI3 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/172713:B4V02_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A222WH92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/172713:B4V02_RS22640 ^@ http://purl.uniprot.org/uniprot/A0A222WRQ4 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/172713:B4V02_RS18215 ^@ http://purl.uniprot.org/uniprot/A0A222WPN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS25310 ^@ http://purl.uniprot.org/uniprot/A0A222WTB5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/172713:B4V02_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A222WLP2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/172713:B4V02_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A222WLS1 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/172713:B4V02_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A222WIE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/172713:B4V02_RS22250 ^@ http://purl.uniprot.org/uniprot/A0A222WRM7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/172713:B4V02_RS11575 ^@ http://purl.uniprot.org/uniprot/A0A222WLC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS22245 ^@ http://purl.uniprot.org/uniprot/A0A222WTC5 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/172713:B4V02_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A222WRS7 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/172713:B4V02_RS15055 ^@ http://purl.uniprot.org/uniprot/A0A222WP96 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/172713:B4V02_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A222WGR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/172713:B4V02_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A222WGT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/172713:B4V02_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A222WHQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/172713:B4V02_RS24850 ^@ http://purl.uniprot.org/uniprot/A0A222WV55 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A222WP66 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/172713:B4V02_RS25110 ^@ http://purl.uniprot.org/uniprot/A0A222WVA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the YabA family.|||Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.|||Involved in initiation control of chromosome replication. http://togogenome.org/gene/172713:B4V02_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A222WK45 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS25625 ^@ http://purl.uniprot.org/uniprot/A0A222WV30 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/172713:B4V02_RS21790 ^@ http://purl.uniprot.org/uniprot/A0A222WT54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS24720 ^@ http://purl.uniprot.org/uniprot/A0A222WV32 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/172713:B4V02_RS23375 ^@ http://purl.uniprot.org/uniprot/A0A222WTW8 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 51 family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/172713:B4V02_RS23845 ^@ http://purl.uniprot.org/uniprot/A0A222WUR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A222WKF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/172713:B4V02_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A222WMZ2 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/172713:B4V02_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A222WLC0 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/172713:B4V02_RS15115 ^@ http://purl.uniprot.org/uniprot/A0A222WP73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/172713:B4V02_RS16285 ^@ http://purl.uniprot.org/uniprot/A0A222WQ60 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/172713:B4V02_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A222WTI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/172713:B4V02_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A222WGS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A222WHB8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/172713:B4V02_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A222WKU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/172713:B4V02_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A222WI02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS19545 ^@ http://purl.uniprot.org/uniprot/A0A222WSM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS21165 ^@ http://purl.uniprot.org/uniprot/A0A222WSR5 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/172713:B4V02_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A222WV76 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A222WGQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS15095 ^@ http://purl.uniprot.org/uniprot/A0A222WPS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/172713:B4V02_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A222WVE8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/172713:B4V02_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A222WJR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/172713:B4V02_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A222WPT2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS06835 ^@ http://purl.uniprot.org/uniprot/A0A222WJP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS24985 ^@ http://purl.uniprot.org/uniprot/A0A222WSX3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/172713:B4V02_RS25475 ^@ http://purl.uniprot.org/uniprot/A0A222WUU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A222WIK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS19205 ^@ http://purl.uniprot.org/uniprot/A0A222WQ65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A222WMF5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/172713:B4V02_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A222WMX3 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A222WK12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/172713:B4V02_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A222WHZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/172713:B4V02_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A222WLP0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/172713:B4V02_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A222WR79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A222WH75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/172713:B4V02_RS21230 ^@ http://purl.uniprot.org/uniprot/A0A222WQZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/172713:B4V02_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A222WQF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/172713:B4V02_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A222WV95 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS15280 ^@ http://purl.uniprot.org/uniprot/A0A222WPM0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A222WLJ4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/172713:B4V02_RS24765 ^@ http://purl.uniprot.org/uniprot/A0A222WSR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/172713:B4V02_RS25020 ^@ http://purl.uniprot.org/uniprot/A0A222WU71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/172713:B4V02_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A222WHQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A222WI67 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/172713:B4V02_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A222WKD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A222WR59 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/172713:B4V02_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A222WI22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A222WIT7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/172713:B4V02_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A222WKI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Catalyzes the conversion of pyruvate to formate and acetyl-CoA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS16925 ^@ http://purl.uniprot.org/uniprot/A0A222WQP9 ^@ Similarity ^@ Belongs to the alpha/beta-type SASP family. http://togogenome.org/gene/172713:B4V02_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A222WKL4 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/172713:B4V02_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A222WJK5 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A222WJU9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/172713:B4V02_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A222WM16 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/172713:B4V02_RS21255 ^@ http://purl.uniprot.org/uniprot/A0A222WVD8 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/172713:B4V02_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A222WJN1 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/172713:B4V02_RS17600 ^@ http://purl.uniprot.org/uniprot/A0A222WPC8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/172713:B4V02_RS15130 ^@ http://purl.uniprot.org/uniprot/A0A222WN83 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A222WKV2 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/172713:B4V02_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A222WHR5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/172713:B4V02_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A222WNX2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/172713:B4V02_RS15165 ^@ http://purl.uniprot.org/uniprot/A0A222WP85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A222WHN6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/172713:B4V02_RS14290 ^@ http://purl.uniprot.org/uniprot/A0A222WMP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS18755 ^@ http://purl.uniprot.org/uniprot/A0A222WQ05 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/172713:B4V02_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A222WQP4 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/172713:B4V02_RS16730 ^@ http://purl.uniprot.org/uniprot/A0A222WP26 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A222WL88 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/172713:B4V02_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A222WH72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/172713:B4V02_RS23045 ^@ http://purl.uniprot.org/uniprot/A0A222WTR5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/172713:B4V02_RS15135 ^@ http://purl.uniprot.org/uniprot/A0A222WN06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A222WUP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A222WGS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/172713:B4V02_RS20390 ^@ http://purl.uniprot.org/uniprot/A0A222WQQ4 ^@ Similarity ^@ Belongs to the CAPAB/TerDEXZ family. http://togogenome.org/gene/172713:B4V02_RS14235 ^@ http://purl.uniprot.org/uniprot/A0A222WNQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A222WK07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A222WMX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/172713:B4V02_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A222WJB6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A222WJY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/172713:B4V02_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A222WHT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A222WH25 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/172713:B4V02_RS13505 ^@ http://purl.uniprot.org/uniprot/A0A222WM92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family. YeeN subfamily.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A222WPG6 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/172713:B4V02_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A222WIN8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/172713:B4V02_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A222WJL8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/172713:B4V02_RS15260 ^@ http://purl.uniprot.org/uniprot/A0A222WPW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/172713:B4V02_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A222WIL0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/172713:B4V02_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A222WL89 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/172713:B4V02_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A222WH93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A222WIN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS14945 ^@ http://purl.uniprot.org/uniprot/A0A222WPM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/172713:B4V02_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A222WM31 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS16335 ^@ http://purl.uniprot.org/uniprot/A0A222WQ54 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A222WNR8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/172713:B4V02_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A222WK23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A222WKN6 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/172713:B4V02_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A222WI66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A222WK22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A222WGT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A222WM76 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/172713:B4V02_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A222WHZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0316 family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS24540 ^@ http://purl.uniprot.org/uniprot/A0A222WUB7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A222WH97 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/172713:B4V02_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A222WLP8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A222WMC9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/172713:B4V02_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A222WJR9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS24560 ^@ http://purl.uniprot.org/uniprot/A0A222WUH0 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/172713:B4V02_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A222WJK9 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/172713:B4V02_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A222WJR6 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/172713:B4V02_RS14130 ^@ http://purl.uniprot.org/uniprot/A0A222WNN9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A222WKZ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/172713:B4V02_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A222WLE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS25210 ^@ http://purl.uniprot.org/uniprot/A0A222WT03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/172713:B4V02_RS24915 ^@ http://purl.uniprot.org/uniprot/A0A222WU51 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A222WLM1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/172713:B4V02_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A222WH81 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/172713:B4V02_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A222WK84 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/172713:B4V02_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A222WL52 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A222WIE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/172713:B4V02_RS15245 ^@ http://purl.uniprot.org/uniprot/A0A222WQ96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/172713:B4V02_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A222WQ64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A222WLY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A222WJE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/172713:B4V02_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A222WJR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS24715 ^@ http://purl.uniprot.org/uniprot/A0A222WSQ8 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/172713:B4V02_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A222WQ86 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/172713:B4V02_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A222WKG0 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/172713:B4V02_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A222WKG3 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/172713:B4V02_RS25075 ^@ http://purl.uniprot.org/uniprot/A0A222WU93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease M5 family.|||Cytoplasm|||Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. http://togogenome.org/gene/172713:B4V02_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A222WLI0 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/172713:B4V02_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A222WIB0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/172713:B4V02_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A222WMH0 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/172713:B4V02_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A222WJC1 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/172713:B4V02_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A222WKW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A222WND6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/172713:B4V02_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A222WQ98 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/172713:B4V02_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A222WLG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A222WGV9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. http://togogenome.org/gene/172713:B4V02_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A222WJQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/172713:B4V02_RS24855 ^@ http://purl.uniprot.org/uniprot/A0A222WUX6 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/172713:B4V02_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A222WIX9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/172713:B4V02_RS20230 ^@ http://purl.uniprot.org/uniprot/A0A222WSY4 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/172713:B4V02_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A222WHP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/172713:B4V02_RS24160 ^@ http://purl.uniprot.org/uniprot/A0A222WUA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS18870 ^@ http://purl.uniprot.org/uniprot/A0A222WPV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A222WGD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS15540 ^@ http://purl.uniprot.org/uniprot/A0A222WNF8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/172713:B4V02_RS19375 ^@ http://purl.uniprot.org/uniprot/A0A222WS02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacteriophage holin family. Cp-1 holin subfamily.|||Membrane http://togogenome.org/gene/172713:B4V02_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A222WHT6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/172713:B4V02_RS18990 ^@ http://purl.uniprot.org/uniprot/A0A222WVC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/172713:B4V02_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A222WP49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A222WLC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/172713:B4V02_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A222WH70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/172713:B4V02_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A222WGR2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/172713:B4V02_RS25200 ^@ http://purl.uniprot.org/uniprot/A0A222WT80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/172713:B4V02_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A222WNC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/172713:B4V02_RS14140 ^@ http://purl.uniprot.org/uniprot/A0A222WMM4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/172713:B4V02_RS24845 ^@ http://purl.uniprot.org/uniprot/A0A222WUL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS24690 ^@ http://purl.uniprot.org/uniprot/A0A222WUK1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/172713:B4V02_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A222WSP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A222WGI6 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/172713:B4V02_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A222WM83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/172713:B4V02_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A222WR46 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/172713:B4V02_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A222WIC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/172713:B4V02_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A222WI60 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/172713:B4V02_RS18970 ^@ http://purl.uniprot.org/uniprot/A0A222WRY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/172713:B4V02_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A222WSH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/172713:B4V02_RS16350 ^@ http://purl.uniprot.org/uniprot/A0A222WQ67 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS16190 ^@ http://purl.uniprot.org/uniprot/A0A222WNL0 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/172713:B4V02_RS24265 ^@ http://purl.uniprot.org/uniprot/A0A222WSF5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A222WIK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/172713:B4V02_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A222WHS4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/172713:B4V02_RS21370 ^@ http://purl.uniprot.org/uniprot/A0A222WSX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A222WLE7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/172713:B4V02_RS21375 ^@ http://purl.uniprot.org/uniprot/A0A222WTL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/172713:B4V02_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A222WHY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/172713:B4V02_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A222WHI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/172713:B4V02_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A222WNP2 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/172713:B4V02_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A222WL72 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/172713:B4V02_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A222WRG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/172713:B4V02_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A222WMT3 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/172713:B4V02_RS15155 ^@ http://purl.uniprot.org/uniprot/A0A222WPS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/172713:B4V02_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A222WKZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/172713:B4V02_RS23515 ^@ http://purl.uniprot.org/uniprot/A0A222WS51 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/172713:B4V02_RS15340 ^@ http://purl.uniprot.org/uniprot/A0A222WN51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/172713:B4V02_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A222WHU5 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/172713:B4V02_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A222WI85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/172713:B4V02_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A222WKN2 ^@ Similarity ^@ Belongs to the UPF0473 family.