http://togogenome.org/gene/178339:BH719_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A1D8B253 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/178339:BH719_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3N0 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/178339:BH719_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V3 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/178339:BH719_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A1D8B272 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/178339:BH719_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2R5 ^@ Similarity|||Subunit ^@ Belongs to the multicopper oxidase family.|||Homotrimer. http://togogenome.org/gene/178339:BH719_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A1D8B265 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/178339:BH719_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A1D8B370 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0A0 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/178339:BH719_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z8 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/178339:BH719_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1R5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Y7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/178339:BH719_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A1D8B235 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/178339:BH719_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2L2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3W3 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/178339:BH719_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Q5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/178339:BH719_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A1D8B133 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/178339:BH719_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A1D8B143 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/178339:BH719_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A1D8B331 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/178339:BH719_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0N2 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/178339:BH719_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A1D8B161 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/178339:BH719_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2V7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/178339:BH719_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/178339:BH719_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/178339:BH719_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2G6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/178339:BH719_RS00100 ^@ http://purl.uniprot.org/uniprot/A0A1D8B035 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/178339:BH719_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3G9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/178339:BH719_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4H5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/178339:BH719_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2D8 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/178339:BH719_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A1D8B414 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/178339:BH719_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A1D8B217 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B132 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/178339:BH719_RS04425 ^@ http://purl.uniprot.org/uniprot/A0A1D8B227 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/178339:BH719_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/178339:BH719_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/178339:BH719_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/178339:BH719_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3T4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/178339:BH719_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A1D8B430 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/178339:BH719_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A1D8B020 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/178339:BH719_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A1D8B226 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/178339:BH719_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A1D8B298 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS01970 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0W5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A1D8B051 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/178339:BH719_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/178339:BH719_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1I9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Q6 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/178339:BH719_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3W5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Y4 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/178339:BH719_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/178339:BH719_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A1D8B163 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A1D8B057 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/178339:BH719_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B060 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/178339:BH719_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/178339:BH719_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/178339:BH719_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A1D8B045 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/178339:BH719_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2H6 ^@ Function|||Similarity ^@ Belongs to the GrpE family.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/178339:BH719_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A1D8B233 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A1D8B196 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/178339:BH719_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3L8 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/178339:BH719_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A1D8B291 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A1D8B028 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A1D8B209 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A1D8B160 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/178339:BH719_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A1D8B404 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/178339:BH719_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/178339:BH719_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A1D8B067 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/178339:BH719_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2R1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1D7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4H8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/178339:BH719_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1W3 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/178339:BH719_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A1D8B342 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/178339:BH719_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3E5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/178339:BH719_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A1D8B243 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/178339:BH719_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3S3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/178339:BH719_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1S6 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/178339:BH719_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A1D8B022 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A1D8B401 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3H8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/178339:BH719_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1K5 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/178339:BH719_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3K3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/178339:BH719_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A1D8B318 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A1D8B225 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/178339:BH719_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A1D8B395 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/178339:BH719_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Membrane http://togogenome.org/gene/178339:BH719_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1T3 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/178339:BH719_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0K9 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/178339:BH719_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A1D8B471 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A1D8B099 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/178339:BH719_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/178339:BH719_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1I0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/178339:BH719_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0B4 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/178339:BH719_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1I2 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/178339:BH719_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1G5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z0 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/178339:BH719_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A1D8B068 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A1D8B436 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/178339:BH719_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A1D8B121 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/178339:BH719_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A1D8B065 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/178339:BH719_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2N3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/178339:BH719_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1S9 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/178339:BH719_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0K0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/178339:BH719_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A1D8B319 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Z9 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/178339:BH719_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U3 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/178339:BH719_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3V9 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/178339:BH719_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A1D8B449 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-fucose isomerase family.|||Converts the aldose L-fucose into the corresponding ketose L-fuculose.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4E5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/178339:BH719_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A1D8B250 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/178339:BH719_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1L2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0R9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/178339:BH719_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1V3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2K4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/178339:BH719_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2G5 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/178339:BH719_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A1D8B244 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/178339:BH719_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A1D8B151 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/178339:BH719_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Q6 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/178339:BH719_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A1D8B423 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/178339:BH719_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3T2 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/178339:BH719_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1C3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/178339:BH719_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A1D8B438 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A1D8B152 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2F8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A1D8B411 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/178339:BH719_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A1D8B222 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/178339:BH719_RS07195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A1D8B434 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1G4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/178339:BH719_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A1D8B070 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A1D8B095 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/178339:BH719_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0G1 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/178339:BH719_RS05700 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2P7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/178339:BH719_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4E8 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/178339:BH719_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A1D8B412 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S8 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/178339:BH719_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3H7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/178339:BH719_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A1D8B420 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/178339:BH719_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0W2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/178339:BH719_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0G9 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A1D8B248 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/178339:BH719_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0D0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/178339:BH719_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3X8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/178339:BH719_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2R7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2N5 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/178339:BH719_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A1D8B381 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A1D8B097 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/178339:BH719_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0B6 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/178339:BH719_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A1D8B413 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/178339:BH719_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/178339:BH719_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A1D8B047 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4G7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/178339:BH719_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A1D8B165 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3F9 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/178339:BH719_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2M7 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/178339:BH719_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/178339:BH719_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A1D8B294 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/178339:BH719_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/178339:BH719_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0E3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/178339:BH719_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A1D8B062 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/178339:BH719_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A1D8B063 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/178339:BH719_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/178339:BH719_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A1D8B119 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/178339:BH719_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3B2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/178339:BH719_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3L1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/178339:BH719_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A1D8B175 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/178339:BH719_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1P3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/178339:BH719_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/178339:BH719_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A1D8B367 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/178339:BH719_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A1D8B416 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/178339:BH719_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J3 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/178339:BH719_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1X6 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/178339:BH719_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/178339:BH719_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A1D8B278 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/178339:BH719_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A1D8B072 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/178339:BH719_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B193 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/178339:BH719_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A1D8B421 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/178339:BH719_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A1D8B054 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/178339:BH719_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0L6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/178339:BH719_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2J5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/178339:BH719_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Q8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/178339:BH719_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3B6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/178339:BH719_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A1D8B309 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/178339:BH719_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4E9 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/178339:BH719_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B350 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2V6 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/178339:BH719_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A1D8B388 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/178339:BH719_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A1D8B269 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/178339:BH719_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/178339:BH719_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A1D8B134 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B046 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/178339:BH719_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A1D8B207 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/178339:BH719_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A1D8B208 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A1D8B044 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A1D8B245 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/178339:BH719_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2L4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J4 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/178339:BH719_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/178339:BH719_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0A2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/178339:BH719_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A1D8B031 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/178339:BH719_RS07340 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A1D8B313 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1X5 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/178339:BH719_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3V3 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/178339:BH719_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/178339:BH719_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V0 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/178339:BH719_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/178339:BH719_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Fes family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A1D8B052 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/178339:BH719_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B176 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/178339:BH719_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A1D8B287 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/178339:BH719_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0X1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1H7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/178339:BH719_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B033 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3N2 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/178339:BH719_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1N4 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/178339:BH719_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2H2 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/178339:BH719_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A1D8B114 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/178339:BH719_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A1D8B408 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3S4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/178339:BH719_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3N3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/178339:BH719_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2X6 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/178339:BH719_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B249 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A1D8B386 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A1D8B254 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/178339:BH719_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1C4 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/178339:BH719_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B101 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/178339:BH719_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A1D8B251 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/178339:BH719_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B135 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/178339:BH719_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Q8 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/178339:BH719_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/178339:BH719_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A1D8B257 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/178339:BH719_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A1D8B498 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A1D8B094 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A1D8B210 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRP transporter (TC 2.A.7.5) family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Q5 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/178339:BH719_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0D9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/178339:BH719_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2P5 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/178339:BH719_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A1D8B215 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A1D8B442 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/178339:BH719_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A1D8B113 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/178339:BH719_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A1D8B379 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/178339:BH719_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3I7 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/178339:BH719_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A1D8B234 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3W9 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/178339:BH719_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/178339:BH719_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1S2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/178339:BH719_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A1D8B256 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/178339:BH719_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2I0 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/178339:BH719_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A1D8B110 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/178339:BH719_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2K8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A1D8B363 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/178339:BH719_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2K7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/178339:BH719_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A1D8B189 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2N2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/178339:BH719_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B344 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/178339:BH719_RS06640 ^@ http://purl.uniprot.org/uniprot/A0A1D8B343 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/178339:BH719_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2J7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/178339:BH719_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A1D8B238 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/178339:BH719_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A1D8B355 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/178339:BH719_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A1D8B195 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A1D8B237 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/178339:BH719_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A1D8B228 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/178339:BH719_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A1D8B473 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/178339:BH719_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A1D8B241 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/178339:BH719_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A1D8B419 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/178339:BH719_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3C2 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/178339:BH719_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0L4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/178339:BH719_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A1D8B276 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/178339:BH719_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A1D8B324 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/178339:BH719_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/178339:BH719_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A1D8B345 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/178339:BH719_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A1D8B088 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/178339:BH719_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A1D8B297 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B3 ^@ Similarity ^@ Belongs to the PNP/MTAP phosphorylase family. http://togogenome.org/gene/178339:BH719_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A1D8B261 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Y7 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/178339:BH719_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2Z7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/178339:BH719_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A1D8B252 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/178339:BH719_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4C3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/178339:BH719_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2L8 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/178339:BH719_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z3 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/178339:BH719_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3M4 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/178339:BH719_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0L7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/178339:BH719_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A1D8B433 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/178339:BH719_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0C0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A1D8B450 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1P6 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/178339:BH719_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A1D8B124 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/178339:BH719_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A1D8B327 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/178339:BH719_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3E3 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/178339:BH719_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A1D8B064 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A1D8B286 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Z7 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/178339:BH719_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4B1 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0D5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/178339:BH719_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A1D8B448 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/178339:BH719_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0A1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/178339:BH719_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A1D8B115 ^@ Similarity ^@ Belongs to the malic enzymes family. http://togogenome.org/gene/178339:BH719_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A1D8B255 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A1D8B406 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/178339:BH719_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A1D8B150 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/178339:BH719_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B214 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/178339:BH719_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V5 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/178339:BH719_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B236 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/178339:BH719_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Y9 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2E2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/178339:BH719_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A1D8B317 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0R7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A1D8B417 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/178339:BH719_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/178339:BH719_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A1D8B027 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/178339:BH719_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/178339:BH719_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1G1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/178339:BH719_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0F4 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/178339:BH719_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0F9 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/178339:BH719_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/178339:BH719_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2E7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/178339:BH719_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/178339:BH719_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A1D8B109 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/178339:BH719_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Y6 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/178339:BH719_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2R3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/178339:BH719_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A1D8B103 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3D6 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/178339:BH719_RS00630 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0F2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/178339:BH719_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2E9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/178339:BH719_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A1D8B104 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1X4 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/178339:BH719_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A1D8B357 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V2 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/178339:BH719_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A1D8B275 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/178339:BH719_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A1D8B032 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/178339:BH719_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1C8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/178339:BH719_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/178339:BH719_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Q1 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A1D8B083 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/178339:BH719_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A1D8B486 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B258 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/178339:BH719_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1M4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/178339:BH719_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A1D8B308 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/178339:BH719_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B268 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/178339:BH719_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2L5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A1D8B239 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1A9 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/178339:BH719_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/178339:BH719_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0F0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/178339:BH719_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/178339:BH719_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1U3 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/178339:BH719_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A1D8B336 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4C8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/178339:BH719_RS04395 ^@ http://purl.uniprot.org/uniprot/A0A1D8B230 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/178339:BH719_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A1D8B338 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/178339:BH719_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A1D8B166 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1V5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/178339:BH719_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0C1 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/178339:BH719_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A1D8B364 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/178339:BH719_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A1D8B339 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/178339:BH719_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3K5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/178339:BH719_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A1D8B424 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/178339:BH719_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A1D8B240 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/178339:BH719_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A1D8B359 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/178339:BH719_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A1D8B484 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/178339:BH719_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A1D8B116 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/178339:BH719_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1K2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/178339:BH719_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.|||Periplasm|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/178339:BH719_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3F3 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/178339:BH719_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0D6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/178339:BH719_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Z4 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/178339:BH719_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A1D8B368 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A1D8B300 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A1D8B259 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/178339:BH719_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A1D8B107 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/178339:BH719_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/178339:BH719_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0M9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/178339:BH719_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/178339:BH719_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3E6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/178339:BH719_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/178339:BH719_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A1D8B246 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B9 ^@ Similarity ^@ Belongs to the bleomycin resistance protein family. http://togogenome.org/gene/178339:BH719_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2I3 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/178339:BH719_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/178339:BH719_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A1D8B441 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/178339:BH719_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A1D8B260 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/178339:BH719_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B483 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/178339:BH719_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A1D8B223 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/178339:BH719_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A1D8B089 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/178339:BH719_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1R1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/178339:BH719_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4B2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1J0 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/178339:BH719_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/178339:BH719_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A1D8B014 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/178339:BH719_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A1D8B288 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/178339:BH719_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1I5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/178339:BH719_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A1D8B102 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/178339:BH719_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A1D8B409 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A1D8B270 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/178339:BH719_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A1D8B197 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/178339:BH719_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A1D8B202 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/178339:BH719_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/178339:BH719_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4H3 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/178339:BH719_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3Q2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/178339:BH719_RS07200 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/178339:BH719_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2B5 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/178339:BH719_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1B0 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/178339:BH719_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A1D8B415 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A1D8B443 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/178339:BH719_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00745 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0E1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A1D8B145 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0P6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/178339:BH719_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A1D8B405 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/178339:BH719_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0B1 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/178339:BH719_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A1D8B084 ^@ Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. http://togogenome.org/gene/178339:BH719_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3S5 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/178339:BH719_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2V5 ^@ Function ^@ Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/178339:BH719_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A1D8B120 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/178339:BH719_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1N5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/178339:BH719_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2G1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/178339:BH719_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A1D8B232 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/178339:BH719_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Q0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/178339:BH719_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A1D8B264 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/178339:BH719_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4C9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/178339:BH719_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3R3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/178339:BH719_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1R0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1L3 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/178339:BH719_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A1D8B139 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/178339:BH719_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/178339:BH719_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0K6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/178339:BH719_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A1D8B247 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/178339:BH719_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4M7 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/178339:BH719_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1V7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/178339:BH719_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2I2 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/178339:BH719_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A1D8B303 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/178339:BH719_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/178339:BH719_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1L1 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/178339:BH719_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0A4 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/178339:BH719_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Z6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/178339:BH719_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A1D8B181 ^@ Caution|||Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A1D8B059 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/178339:BH719_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1Y8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/178339:BH719_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3E0 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/178339:BH719_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2S2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2A7 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/178339:BH719_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A1D8B090 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0I2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/178339:BH719_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A1D8B218 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/178339:BH719_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1W4 ^@ Function|||Similarity ^@ Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/178339:BH719_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0U7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/178339:BH719_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1W1 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/178339:BH719_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A1D8B488 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/178339:BH719_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0E9 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/178339:BH719_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A1D8B131 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/178339:BH719_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A1D8B078 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/178339:BH719_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A1D8B425 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/178339:BH719_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A1D8B323 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/178339:BH719_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A1D8B093 ^@ Similarity ^@ Belongs to the prokaryotic ubiquitin-like protein family. http://togogenome.org/gene/178339:BH719_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A1D8B075 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/178339:BH719_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1F5 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/178339:BH719_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A1D8B3R6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A1D8B216 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/178339:BH719_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/178339:BH719_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Y6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/178339:BH719_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A1D8B4A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/178339:BH719_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A1D8B056 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/178339:BH719_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Z6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/178339:BH719_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A1D8B123 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/178339:BH719_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0C5 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/178339:BH719_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0R4 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/178339:BH719_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A1D8B453 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/178339:BH719_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1E0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/178339:BH719_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A1D8B2Q7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/178339:BH719_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0N9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/178339:BH719_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A1D8B1F6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/178339:BH719_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A1D8B333 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/178339:BH719_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A1D8B378 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/178339:BH719_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A1D8B282 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/178339:BH719_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A1D8B0Y0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.