http://togogenome.org/gene/351607:ACEL_RS01725 ^@ http://purl.uniprot.org/uniprot/A0LRP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/351607:ACEL_RS09690 ^@ http://purl.uniprot.org/uniprot/A0LW39 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/351607:ACEL_RS05765 ^@ http://purl.uniprot.org/uniprot/A0LTY3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/351607:ACEL_RS02755 ^@ http://purl.uniprot.org/uniprot/A0LS98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS08520 ^@ http://purl.uniprot.org/uniprot/A0LVG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS01050 ^@ http://purl.uniprot.org/uniprot/A0LRB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/351607:ACEL_RS01545 ^@ http://purl.uniprot.org/uniprot/A0LRK9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/351607:ACEL_RS10195 ^@ http://purl.uniprot.org/uniprot/A0LWD7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/351607:ACEL_RS06400 ^@ http://purl.uniprot.org/uniprot/A0LUA7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/351607:ACEL_RS09305 ^@ http://purl.uniprot.org/uniprot/A0LVW2 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/351607:ACEL_RS09645 ^@ http://purl.uniprot.org/uniprot/A0LW30 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MshB deacetylase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. http://togogenome.org/gene/351607:ACEL_RS09990 ^@ http://purl.uniprot.org/uniprot/A0LW96 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/351607:ACEL_RS07680 ^@ http://purl.uniprot.org/uniprot/A0LV04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS07745 ^@ http://purl.uniprot.org/uniprot/A0LV14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/351607:ACEL_RS01705 ^@ http://purl.uniprot.org/uniprot/A0LRP1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS00245 ^@ http://purl.uniprot.org/uniprot/A0LQW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS10355 ^@ http://purl.uniprot.org/uniprot/A0LWG8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/351607:ACEL_RS03305 ^@ http://purl.uniprot.org/uniprot/A0LSK5 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/351607:ACEL_RS03635 ^@ http://purl.uniprot.org/uniprot/A0LSS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/351607:ACEL_RS10930 ^@ http://purl.uniprot.org/uniprot/A0LWS1 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/351607:ACEL_RS04440 ^@ http://purl.uniprot.org/uniprot/A0LT71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/351607:ACEL_RS08745 ^@ http://purl.uniprot.org/uniprot/A0LVK8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/351607:ACEL_RS06895 ^@ http://purl.uniprot.org/uniprot/A0LUK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/351607:ACEL_RS09410 ^@ http://purl.uniprot.org/uniprot/A0LVY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/351607:ACEL_RS03340 ^@ http://purl.uniprot.org/uniprot/A0LSL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. http://togogenome.org/gene/351607:ACEL_RS06110 ^@ http://purl.uniprot.org/uniprot/A0LU50 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/351607:ACEL_RS08350 ^@ http://purl.uniprot.org/uniprot/A0LVD2 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS09745 ^@ http://purl.uniprot.org/uniprot/A0LW50 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/351607:ACEL_RS08160 ^@ http://purl.uniprot.org/uniprot/A0LV98 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS07320 ^@ http://purl.uniprot.org/uniprot/A0LUT3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/351607:ACEL_RS02375 ^@ http://purl.uniprot.org/uniprot/A0LS22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04695 ^@ http://purl.uniprot.org/uniprot/A0LTC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01230 ^@ http://purl.uniprot.org/uniprot/A0LRE9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/351607:ACEL_RS08910 ^@ http://purl.uniprot.org/uniprot/A0LVP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/351607:ACEL_RS06630 ^@ http://purl.uniprot.org/uniprot/A0LUF0 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Catalyzes the reversible reductive amination of pyruvate to L-alanine. http://togogenome.org/gene/351607:ACEL_RS06310 ^@ http://purl.uniprot.org/uniprot/A0LU90 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/351607:ACEL_RS05885 ^@ http://purl.uniprot.org/uniprot/A0LU07 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS03790 ^@ http://purl.uniprot.org/uniprot/A0LSU9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/351607:ACEL_RS04345 ^@ http://purl.uniprot.org/uniprot/A0LT53 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/351607:ACEL_RS05535 ^@ http://purl.uniprot.org/uniprot/A0LTT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS06800 ^@ http://purl.uniprot.org/uniprot/A0LUI4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/351607:ACEL_RS01920 ^@ http://purl.uniprot.org/uniprot/A0LRT5 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06105 ^@ http://purl.uniprot.org/uniprot/A0LU49 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/351607:ACEL_RS01115 ^@ http://purl.uniprot.org/uniprot/A0LRC6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/351607:ACEL_RS04085 ^@ http://purl.uniprot.org/uniprot/A0LT06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS00480 ^@ http://purl.uniprot.org/uniprot/A0LR06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/351607:ACEL_RS04835 ^@ http://purl.uniprot.org/uniprot/A0LTE9 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/351607:ACEL_RS06525 ^@ http://purl.uniprot.org/uniprot/A0LUC9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/351607:ACEL_RS04350 ^@ http://purl.uniprot.org/uniprot/A0LT54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/351607:ACEL_RS02500 ^@ http://purl.uniprot.org/uniprot/A0LS46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS05105 ^@ http://purl.uniprot.org/uniprot/A0LTK4 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/351607:ACEL_RS02010 ^@ http://purl.uniprot.org/uniprot/A0LRV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01525 ^@ http://purl.uniprot.org/uniprot/A0LRK6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/351607:ACEL_RS00580 ^@ http://purl.uniprot.org/uniprot/A0LR26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04090 ^@ http://purl.uniprot.org/uniprot/A0LT07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/351607:ACEL_RS05195 ^@ http://purl.uniprot.org/uniprot/A0LTM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04770 ^@ http://purl.uniprot.org/uniprot/A0LTD6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/351607:ACEL_RS08385 ^@ http://purl.uniprot.org/uniprot/A0LVD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS00145 ^@ http://purl.uniprot.org/uniprot/A0LQU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS07670 ^@ http://purl.uniprot.org/uniprot/A0LV02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/351607:ACEL_RS04265 ^@ http://purl.uniprot.org/uniprot/A0LT38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS01200 ^@ http://purl.uniprot.org/uniprot/A0LRE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.|||Homooctamer.|||Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. http://togogenome.org/gene/351607:ACEL_RS06715 ^@ http://purl.uniprot.org/uniprot/A0LUG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/351607:ACEL_RS01290 ^@ http://purl.uniprot.org/uniprot/A0LRG2 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/351607:ACEL_RS09685 ^@ http://purl.uniprot.org/uniprot/A0LW38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/351607:ACEL_RS10120 ^@ http://purl.uniprot.org/uniprot/A0LWC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06330 ^@ http://purl.uniprot.org/uniprot/A0LU94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05725 ^@ http://purl.uniprot.org/uniprot/A0LTX5 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/351607:ACEL_RS10365 ^@ http://purl.uniprot.org/uniprot/A0LWG9 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/351607:ACEL_RS04325 ^@ http://purl.uniprot.org/uniprot/A0LT49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/351607:ACEL_RS07980 ^@ http://purl.uniprot.org/uniprot/A0LV61 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/351607:ACEL_RS05275 ^@ http://purl.uniprot.org/uniprot/A0LTN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/351607:ACEL_RS05045 ^@ http://purl.uniprot.org/uniprot/A0LTJ2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/351607:ACEL_RS03330 ^@ http://purl.uniprot.org/uniprot/A0LSL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/351607:ACEL_RS10750 ^@ http://purl.uniprot.org/uniprot/A0LWN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/351607:ACEL_RS02965 ^@ http://purl.uniprot.org/uniprot/A0LSE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01000 ^@ http://purl.uniprot.org/uniprot/A0LRA3 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/351607:ACEL_RS00530 ^@ http://purl.uniprot.org/uniprot/A0LR16 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/351607:ACEL_RS09340 ^@ http://purl.uniprot.org/uniprot/A0LVW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS10900 ^@ http://purl.uniprot.org/uniprot/A0LWR6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/351607:ACEL_RS05780 ^@ http://purl.uniprot.org/uniprot/A0LTY6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS08020 ^@ http://purl.uniprot.org/uniprot/A0LV69 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/351607:ACEL_RS03765 ^@ http://purl.uniprot.org/uniprot/A0LSU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS00675 ^@ http://purl.uniprot.org/uniprot/A0LR43 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/351607:ACEL_RS03510 ^@ http://purl.uniprot.org/uniprot/A0LSP5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/351607:ACEL_RS03065 ^@ http://purl.uniprot.org/uniprot/A0LSG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS03180 ^@ http://purl.uniprot.org/uniprot/A0LSI2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family. http://togogenome.org/gene/351607:ACEL_RS09440 ^@ http://purl.uniprot.org/uniprot/A0LVY8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/351607:ACEL_RS08070 ^@ http://purl.uniprot.org/uniprot/A0LV79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/351607:ACEL_RS06720 ^@ http://purl.uniprot.org/uniprot/A0LUG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/351607:ACEL_RS03380 ^@ http://purl.uniprot.org/uniprot/A0LSL9 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/351607:ACEL_RS02125 ^@ http://purl.uniprot.org/uniprot/A0LRX5 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/351607:ACEL_RS01680 ^@ http://purl.uniprot.org/uniprot/A0LRN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/351607:ACEL_RS05185 ^@ http://purl.uniprot.org/uniprot/A0LTM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS03350 ^@ http://purl.uniprot.org/uniprot/A0LSL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/351607:ACEL_RS03945 ^@ http://purl.uniprot.org/uniprot/A0LSX9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS01415 ^@ http://purl.uniprot.org/uniprot/A0LRI7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS05530 ^@ http://purl.uniprot.org/uniprot/A0LTT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/351607:ACEL_RS07995 ^@ http://purl.uniprot.org/uniprot/A0LV64 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/351607:ACEL_RS05175 ^@ http://purl.uniprot.org/uniprot/A0LTL8 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS05215 ^@ http://purl.uniprot.org/uniprot/A0LTM6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/351607:ACEL_RS06680 ^@ http://purl.uniprot.org/uniprot/A0LUG0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS09405 ^@ http://purl.uniprot.org/uniprot/A0LVY2 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS06510 ^@ http://purl.uniprot.org/uniprot/A0LUC6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/351607:ACEL_RS01605 ^@ http://purl.uniprot.org/uniprot/A0LRM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS06540 ^@ http://purl.uniprot.org/uniprot/A0LUD2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/351607:ACEL_RS05660 ^@ http://purl.uniprot.org/uniprot/A0LTW2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS03500 ^@ http://purl.uniprot.org/uniprot/A0LSP3 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/351607:ACEL_RS05125 ^@ http://purl.uniprot.org/uniprot/A0LTK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/351607:ACEL_RS10705 ^@ http://purl.uniprot.org/uniprot/A0LWM7 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/351607:ACEL_RS04860 ^@ http://purl.uniprot.org/uniprot/A0LTF4 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/351607:ACEL_RS04670 ^@ http://purl.uniprot.org/uniprot/A0LTB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS08800 ^@ http://purl.uniprot.org/uniprot/A0LVL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/351607:ACEL_RS10055 ^@ http://purl.uniprot.org/uniprot/A0LWA9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS04755 ^@ http://purl.uniprot.org/uniprot/A0LTD3 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/351607:ACEL_RS04850 ^@ http://purl.uniprot.org/uniprot/A0LTF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/351607:ACEL_RS06505 ^@ http://purl.uniprot.org/uniprot/A0LUC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS12190 ^@ http://purl.uniprot.org/uniprot/A0LR61 ^@ Similarity ^@ Belongs to the neocarzinostatin family. http://togogenome.org/gene/351607:ACEL_RS05200 ^@ http://purl.uniprot.org/uniprot/A0LTM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/351607:ACEL_RS06580 ^@ http://purl.uniprot.org/uniprot/A0LUE0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/351607:ACEL_RS10390 ^@ http://purl.uniprot.org/uniprot/A0LWH3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS02935 ^@ http://purl.uniprot.org/uniprot/A0LSD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS08140 ^@ http://purl.uniprot.org/uniprot/A0LV94 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/351607:ACEL_RS01210 ^@ http://purl.uniprot.org/uniprot/A0LRE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS08510 ^@ http://purl.uniprot.org/uniprot/A0LVG2 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/351607:ACEL_RS02615 ^@ http://purl.uniprot.org/uniprot/A0LS69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS07225 ^@ http://purl.uniprot.org/uniprot/A0LUR4 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/351607:ACEL_RS10420 ^@ http://purl.uniprot.org/uniprot/A0LWH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/351607:ACEL_RS01990 ^@ http://purl.uniprot.org/uniprot/A0LRU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS10180 ^@ http://purl.uniprot.org/uniprot/A0LWD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/351607:ACEL_RS06325 ^@ http://purl.uniprot.org/uniprot/A0LU93 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/351607:ACEL_RS00885 ^@ http://purl.uniprot.org/uniprot/A0LR83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/351607:ACEL_RS06125 ^@ http://purl.uniprot.org/uniprot/A0LU53 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/351607:ACEL_RS10440 ^@ http://purl.uniprot.org/uniprot/A0LWI0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03755 ^@ http://purl.uniprot.org/uniprot/A0LSU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01555 ^@ http://purl.uniprot.org/uniprot/A0LRL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/351607:ACEL_RS06690 ^@ http://purl.uniprot.org/uniprot/A0LUG2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/351607:ACEL_RS09855 ^@ http://purl.uniprot.org/uniprot/A0LW71 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/351607:ACEL_RS02255 ^@ http://purl.uniprot.org/uniprot/A0LRZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS08700 ^@ http://purl.uniprot.org/uniprot/A0LVJ9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/351607:ACEL_RS10450 ^@ http://purl.uniprot.org/uniprot/A0LWI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/351607:ACEL_RS06910 ^@ http://purl.uniprot.org/uniprot/A0LUK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/351607:ACEL_RS07010 ^@ http://purl.uniprot.org/uniprot/A0LUM5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/351607:ACEL_RS06930 ^@ http://purl.uniprot.org/uniprot/A0LUK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/351607:ACEL_RS11070 ^@ http://purl.uniprot.org/uniprot/A0LWU5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/351607:ACEL_RS06465 ^@ http://purl.uniprot.org/uniprot/A0LUB7 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/351607:ACEL_RS06595 ^@ http://purl.uniprot.org/uniprot/A0LUE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS05935 ^@ http://purl.uniprot.org/uniprot/A0LU17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS03345 ^@ http://purl.uniprot.org/uniprot/A0LSL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/351607:ACEL_RS05250 ^@ http://purl.uniprot.org/uniprot/A0LTN3 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/351607:ACEL_RS04435 ^@ http://purl.uniprot.org/uniprot/A0LT70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/351607:ACEL_RS01560 ^@ http://purl.uniprot.org/uniprot/A0LRL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/351607:ACEL_RS00400 ^@ http://purl.uniprot.org/uniprot/A0LQZ1 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/351607:ACEL_RS04395 ^@ http://purl.uniprot.org/uniprot/A0LT62 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/351607:ACEL_RS00690 ^@ http://purl.uniprot.org/uniprot/A0LR46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS05065 ^@ http://purl.uniprot.org/uniprot/A0LTJ6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/351607:ACEL_RS00225 ^@ http://purl.uniprot.org/uniprot/A0LQV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02795 ^@ http://purl.uniprot.org/uniprot/A0LSA6 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/351607:ACEL_RS04745 ^@ http://purl.uniprot.org/uniprot/A0LTD1 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS03020 ^@ http://purl.uniprot.org/uniprot/A0LSF3 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/351607:ACEL_RS04035 ^@ http://purl.uniprot.org/uniprot/A0LSZ6 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/351607:ACEL_RS06600 ^@ http://purl.uniprot.org/uniprot/A0LUE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS00025 ^@ http://purl.uniprot.org/uniprot/A0LQS1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/351607:ACEL_RS03545 ^@ http://purl.uniprot.org/uniprot/A0LSQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS11325 ^@ http://purl.uniprot.org/uniprot/A0LRY1 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/351607:ACEL_RS05245 ^@ http://purl.uniprot.org/uniprot/A0LTN2 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/351607:ACEL_RS00525 ^@ http://purl.uniprot.org/uniprot/A0LR15 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/351607:ACEL_RS04315 ^@ http://purl.uniprot.org/uniprot/A0LT47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/351607:ACEL_RS08495 ^@ http://purl.uniprot.org/uniprot/A0LVG0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/351607:ACEL_RS05705 ^@ http://purl.uniprot.org/uniprot/A0LTX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/351607:ACEL_RS07925 ^@ http://purl.uniprot.org/uniprot/A0LV50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS08955 ^@ http://purl.uniprot.org/uniprot/A0LVQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06030 ^@ http://purl.uniprot.org/uniprot/A0LU34 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/351607:ACEL_RS05900 ^@ http://purl.uniprot.org/uniprot/A0LU10 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/351607:ACEL_RS04300 ^@ http://purl.uniprot.org/uniprot/A0LT44 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/351607:ACEL_RS03315 ^@ http://purl.uniprot.org/uniprot/A0LSK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01615 ^@ http://purl.uniprot.org/uniprot/A0LRM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/351607:ACEL_RS08640 ^@ http://purl.uniprot.org/uniprot/A0LVI8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03595 ^@ http://purl.uniprot.org/uniprot/A0LSR2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS01710 ^@ http://purl.uniprot.org/uniprot/A0LRP2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/351607:ACEL_RS00880 ^@ http://purl.uniprot.org/uniprot/A0LR82 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/351607:ACEL_RS05415 ^@ http://purl.uniprot.org/uniprot/A0LTR5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS07775 ^@ http://purl.uniprot.org/uniprot/A0LV20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/351607:ACEL_RS10110 ^@ http://purl.uniprot.org/uniprot/A0LWB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS11055 ^@ http://purl.uniprot.org/uniprot/A0LWU2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/351607:ACEL_RS03335 ^@ http://purl.uniprot.org/uniprot/A0LSL1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/351607:ACEL_RS10695 ^@ http://purl.uniprot.org/uniprot/A0LWM5 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/351607:ACEL_RS01600 ^@ http://purl.uniprot.org/uniprot/A0LRM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/351607:ACEL_RS10735 ^@ http://purl.uniprot.org/uniprot/A0LWN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS10545 ^@ http://purl.uniprot.org/uniprot/A0LWK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/351607:ACEL_RS05335 ^@ http://purl.uniprot.org/uniprot/A0LTP8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS08055 ^@ http://purl.uniprot.org/uniprot/A0LV76 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/351607:ACEL_RS03360 ^@ http://purl.uniprot.org/uniprot/A0LSL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/351607:ACEL_RS06460 ^@ http://purl.uniprot.org/uniprot/A0LUB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS09535 ^@ http://purl.uniprot.org/uniprot/A0LW08 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/351607:ACEL_RS11060 ^@ http://purl.uniprot.org/uniprot/A0LWU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/351607:ACEL_RS07810 ^@ http://purl.uniprot.org/uniprot/A0LV27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/351607:ACEL_RS02105 ^@ http://purl.uniprot.org/uniprot/A0LRX1 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/351607:ACEL_RS07675 ^@ http://purl.uniprot.org/uniprot/A0LV03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS10395 ^@ http://purl.uniprot.org/uniprot/A0LWH4 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/351607:ACEL_RS04975 ^@ http://purl.uniprot.org/uniprot/A0LTH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS12585 ^@ http://purl.uniprot.org/uniprot/A0LT59 ^@ Similarity ^@ Belongs to the peptidase C40 family.|||Belongs to the transglycosylase Slt family. http://togogenome.org/gene/351607:ACEL_RS04040 ^@ http://purl.uniprot.org/uniprot/A0LSZ7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/351607:ACEL_RS00385 ^@ http://purl.uniprot.org/uniprot/A0LQY8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/351607:ACEL_RS07725 ^@ http://purl.uniprot.org/uniprot/A0LV10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS00555 ^@ http://purl.uniprot.org/uniprot/A0LR21 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/351607:ACEL_RS06090 ^@ http://purl.uniprot.org/uniprot/A0LU46 ^@ Domain|||Function|||Similarity|||Subunit ^@ ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.|||Belongs to the AAA ATPase family.|||Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.|||Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets. http://togogenome.org/gene/351607:ACEL_RS02005 ^@ http://purl.uniprot.org/uniprot/A0LRV2 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/351607:ACEL_RS09595 ^@ http://purl.uniprot.org/uniprot/A0LW20 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/351607:ACEL_RS11460 ^@ http://purl.uniprot.org/uniprot/A0LTP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS05850 ^@ http://purl.uniprot.org/uniprot/A0LU00 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/351607:ACEL_RS10625 ^@ http://purl.uniprot.org/uniprot/A0LWL7 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/351607:ACEL_RS04525 ^@ http://purl.uniprot.org/uniprot/A0LT88 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/351607:ACEL_RS11095 ^@ http://purl.uniprot.org/uniprot/A0LWV0 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/351607:ACEL_RS02425 ^@ http://purl.uniprot.org/uniprot/A0LS32 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/351607:ACEL_RS09500 ^@ http://purl.uniprot.org/uniprot/A0LW01 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/351607:ACEL_RS03520 ^@ http://purl.uniprot.org/uniprot/A0LSP7 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/351607:ACEL_RS02000 ^@ http://purl.uniprot.org/uniprot/A0LRV1 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/351607:ACEL_RS01055 ^@ http://purl.uniprot.org/uniprot/A0LRB4 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/351607:ACEL_RS01135 ^@ http://purl.uniprot.org/uniprot/A0LRD0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS11195 ^@ http://purl.uniprot.org/uniprot/A0LWX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/351607:ACEL_RS04730 ^@ http://purl.uniprot.org/uniprot/A0LTC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS08660 ^@ http://purl.uniprot.org/uniprot/A0LVJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/351607:ACEL_RS08765 ^@ http://purl.uniprot.org/uniprot/A0LVL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS04045 ^@ http://purl.uniprot.org/uniprot/A0LSZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS07845 ^@ http://purl.uniprot.org/uniprot/A0LV34 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/351607:ACEL_RS08035 ^@ http://purl.uniprot.org/uniprot/A0LV72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS03625 ^@ http://purl.uniprot.org/uniprot/A0LSR8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03760 ^@ http://purl.uniprot.org/uniprot/A0LSU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04405 ^@ http://purl.uniprot.org/uniprot/A0LT64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS02120 ^@ http://purl.uniprot.org/uniprot/A0LRX4 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/351607:ACEL_RS10230 ^@ http://purl.uniprot.org/uniprot/A0LWE4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/351607:ACEL_RS03225 ^@ http://purl.uniprot.org/uniprot/A0LSI9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/351607:ACEL_RS05285 ^@ http://purl.uniprot.org/uniprot/A0LTN9 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/351607:ACEL_RS10455 ^@ http://purl.uniprot.org/uniprot/A0LWI3 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/351607:ACEL_RS01765 ^@ http://purl.uniprot.org/uniprot/A0LRQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS04390 ^@ http://purl.uniprot.org/uniprot/A0LT61 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/351607:ACEL_RS11170 ^@ http://purl.uniprot.org/uniprot/A0LWW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS10010 ^@ http://purl.uniprot.org/uniprot/A0LWA0 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/351607:ACEL_RS10045 ^@ http://purl.uniprot.org/uniprot/A0LWA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/351607:ACEL_RS10975 ^@ http://purl.uniprot.org/uniprot/A0LWS7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/351607:ACEL_RS10040 ^@ http://purl.uniprot.org/uniprot/A0LWA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/351607:ACEL_RS08185 ^@ http://purl.uniprot.org/uniprot/A0LVA3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/351607:ACEL_RS06865 ^@ http://purl.uniprot.org/uniprot/A0LUJ7 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06835 ^@ http://purl.uniprot.org/uniprot/A0LUJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS08245 ^@ http://purl.uniprot.org/uniprot/A0LVB3 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/351607:ACEL_RS06830 ^@ http://purl.uniprot.org/uniprot/A0LUJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/351607:ACEL_RS06345 ^@ http://purl.uniprot.org/uniprot/A0LU96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS07185 ^@ http://purl.uniprot.org/uniprot/A0LUQ6 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/351607:ACEL_RS10620 ^@ http://purl.uniprot.org/uniprot/A0LWL6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS07005 ^@ http://purl.uniprot.org/uniprot/A0LUM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS06695 ^@ http://purl.uniprot.org/uniprot/A0LUG3 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/351607:ACEL_RS01575 ^@ http://purl.uniprot.org/uniprot/A0LRL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/351607:ACEL_RS01400 ^@ http://purl.uniprot.org/uniprot/A0LRI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS03580 ^@ http://purl.uniprot.org/uniprot/A0LSQ9 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/351607:ACEL_RS08905 ^@ http://purl.uniprot.org/uniprot/A0LVP1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/351607:ACEL_RS01785 ^@ http://purl.uniprot.org/uniprot/A0LRQ8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03455 ^@ http://purl.uniprot.org/uniprot/A0LSN5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/351607:ACEL_RS03300 ^@ http://purl.uniprot.org/uniprot/A0LSK4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/351607:ACEL_RS10755 ^@ http://purl.uniprot.org/uniprot/A0LWN7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/351607:ACEL_RS03285 ^@ http://purl.uniprot.org/uniprot/A0LSK1 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/351607:ACEL_RS10485 ^@ http://purl.uniprot.org/uniprot/A0LWI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS07940 ^@ http://purl.uniprot.org/uniprot/A0LV53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS05800 ^@ http://purl.uniprot.org/uniprot/A0LTZ0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/351607:ACEL_RS01905 ^@ http://purl.uniprot.org/uniprot/A0LRT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS05205 ^@ http://purl.uniprot.org/uniprot/A0LTM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS05915 ^@ http://purl.uniprot.org/uniprot/A0LU13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/351607:ACEL_RS06550 ^@ http://purl.uniprot.org/uniprot/A0LUD4 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/351607:ACEL_RS09965 ^@ http://purl.uniprot.org/uniprot/A0LW92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS07830 ^@ http://purl.uniprot.org/uniprot/A0LV31 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS10815 ^@ http://purl.uniprot.org/uniprot/A0LWQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS01980 ^@ http://purl.uniprot.org/uniprot/A0LRU7 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/351607:ACEL_RS09350 ^@ http://purl.uniprot.org/uniprot/A0LVX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/351607:ACEL_RS00030 ^@ http://purl.uniprot.org/uniprot/A0LQS2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/351607:ACEL_RS08530 ^@ http://purl.uniprot.org/uniprot/A0LVG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02790 ^@ http://purl.uniprot.org/uniprot/A0LSA5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/351607:ACEL_RS04985 ^@ http://purl.uniprot.org/uniprot/A0LTH9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS01595 ^@ http://purl.uniprot.org/uniprot/A0LRL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS07600 ^@ http://purl.uniprot.org/uniprot/A0LUY8 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/351607:ACEL_RS08330 ^@ http://purl.uniprot.org/uniprot/A0LVC8 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/351607:ACEL_RS08100 ^@ http://purl.uniprot.org/uniprot/A0LV85 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/351607:ACEL_RS06925 ^@ http://purl.uniprot.org/uniprot/A0LUK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS10710 ^@ http://purl.uniprot.org/uniprot/A0LWM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS09585 ^@ http://purl.uniprot.org/uniprot/A0LW18 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/351607:ACEL_RS10415 ^@ http://purl.uniprot.org/uniprot/A0LWH7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/351607:ACEL_RS04445 ^@ http://purl.uniprot.org/uniprot/A0LT72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05455 ^@ http://purl.uniprot.org/uniprot/A0LTS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS06145 ^@ http://purl.uniprot.org/uniprot/A0LU57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01690 ^@ http://purl.uniprot.org/uniprot/A0LRN8 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS11035 ^@ http://purl.uniprot.org/uniprot/A0LWT8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/351607:ACEL_RS00015 ^@ http://purl.uniprot.org/uniprot/A0LQR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/351607:ACEL_RS03730 ^@ http://purl.uniprot.org/uniprot/A0LST7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01590 ^@ http://purl.uniprot.org/uniprot/A0LRL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/351607:ACEL_RS06860 ^@ http://purl.uniprot.org/uniprot/A0LUJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03835 ^@ http://purl.uniprot.org/uniprot/A0LSV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS00610 ^@ http://purl.uniprot.org/uniprot/A0LR32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03525 ^@ http://purl.uniprot.org/uniprot/A0LSP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/351607:ACEL_RS09485 ^@ http://purl.uniprot.org/uniprot/A0LVZ8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/351607:ACEL_RS04305 ^@ http://purl.uniprot.org/uniprot/A0LT45 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/351607:ACEL_RS07985 ^@ http://purl.uniprot.org/uniprot/A0LV62 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/351607:ACEL_RS01385 ^@ http://purl.uniprot.org/uniprot/A0LRI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS07195 ^@ http://purl.uniprot.org/uniprot/A0LUQ8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/351607:ACEL_RS07765 ^@ http://purl.uniprot.org/uniprot/A0LV18 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/351607:ACEL_RS04340 ^@ http://purl.uniprot.org/uniprot/A0LT52 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/351607:ACEL_RS05450 ^@ http://purl.uniprot.org/uniprot/A0LTS2 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06115 ^@ http://purl.uniprot.org/uniprot/A0LU51 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/351607:ACEL_RS01395 ^@ http://purl.uniprot.org/uniprot/A0LRI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS08885 ^@ http://purl.uniprot.org/uniprot/A0LVN7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/351607:ACEL_RS08085 ^@ http://purl.uniprot.org/uniprot/A0LV82 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/351607:ACEL_RS11015 ^@ http://purl.uniprot.org/uniprot/A0LWT4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/351607:ACEL_RS01085 ^@ http://purl.uniprot.org/uniprot/A0LRC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01685 ^@ http://purl.uniprot.org/uniprot/A0LRN7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/351607:ACEL_RS02150 ^@ http://purl.uniprot.org/uniprot/A0LRY0 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/351607:ACEL_RS07615 ^@ http://purl.uniprot.org/uniprot/A0LUZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/351607:ACEL_RS04070 ^@ http://purl.uniprot.org/uniprot/A0LT03 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/351607:ACEL_RS06670 ^@ http://purl.uniprot.org/uniprot/A0LUF8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS04825 ^@ http://purl.uniprot.org/uniprot/A0LTE7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/351607:ACEL_RS04740 ^@ http://purl.uniprot.org/uniprot/A0LTD0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/351607:ACEL_RS10960 ^@ http://purl.uniprot.org/uniprot/A0LWS4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer. http://togogenome.org/gene/351607:ACEL_RS04785 ^@ http://purl.uniprot.org/uniprot/A0LTD9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS01650 ^@ http://purl.uniprot.org/uniprot/A0LRN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/351607:ACEL_RS05070 ^@ http://purl.uniprot.org/uniprot/A0LTJ7 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/351607:ACEL_RS01070 ^@ http://purl.uniprot.org/uniprot/A0LRB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS03655 ^@ http://purl.uniprot.org/uniprot/A0LSS4 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/351607:ACEL_RS06615 ^@ http://purl.uniprot.org/uniprot/A0LUE7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS05555 ^@ http://purl.uniprot.org/uniprot/A0LTU2 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/351607:ACEL_RS01450 ^@ http://purl.uniprot.org/uniprot/A0LRJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS04895 ^@ http://purl.uniprot.org/uniprot/A0LTG1 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/351607:ACEL_RS03355 ^@ http://purl.uniprot.org/uniprot/A0LSL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/351607:ACEL_RS10185 ^@ http://purl.uniprot.org/uniprot/A0LWD5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/351607:ACEL_RS11450 ^@ http://purl.uniprot.org/uniprot/A0LTI4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/351607:ACEL_RS01580 ^@ http://purl.uniprot.org/uniprot/A0LRL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/351607:ACEL_RS00605 ^@ http://purl.uniprot.org/uniprot/A0LR31 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/351607:ACEL_RS05305 ^@ http://purl.uniprot.org/uniprot/A0LTP2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/351607:ACEL_RS06585 ^@ http://purl.uniprot.org/uniprot/A0LUE1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/351607:ACEL_RS01520 ^@ http://purl.uniprot.org/uniprot/A0LRK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS00940 ^@ http://purl.uniprot.org/uniprot/A0LR93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/351607:ACEL_RS04505 ^@ http://purl.uniprot.org/uniprot/A0LT84 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/351607:ACEL_RS00495 ^@ http://purl.uniprot.org/uniprot/A0LR09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/351607:ACEL_RS11040 ^@ http://purl.uniprot.org/uniprot/A0LWT9 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/351607:ACEL_RS06470 ^@ http://purl.uniprot.org/uniprot/A0LUB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS00305 ^@ http://purl.uniprot.org/uniprot/A0LQX3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/351607:ACEL_RS02430 ^@ http://purl.uniprot.org/uniprot/A0LS33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS08960 ^@ http://purl.uniprot.org/uniprot/A0LVQ1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/351607:ACEL_RS03990 ^@ http://purl.uniprot.org/uniprot/A0LSY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01435 ^@ http://purl.uniprot.org/uniprot/A0LRJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS08025 ^@ http://purl.uniprot.org/uniprot/A0LV70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/351607:ACEL_RS05710 ^@ http://purl.uniprot.org/uniprot/A0LTX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/351607:ACEL_RS00535 ^@ http://purl.uniprot.org/uniprot/A0LR17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/351607:ACEL_RS04125 ^@ http://purl.uniprot.org/uniprot/A0LT14 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/351607:ACEL_RS04100 ^@ http://purl.uniprot.org/uniprot/A0LT09 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06890 ^@ http://purl.uniprot.org/uniprot/A0LUK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06190 ^@ http://purl.uniprot.org/uniprot/A0LU67 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/351607:ACEL_RS06075 ^@ http://purl.uniprot.org/uniprot/A0LU43 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS07045 ^@ http://purl.uniprot.org/uniprot/A0LUN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/351607:ACEL_RS00595 ^@ http://purl.uniprot.org/uniprot/A0LR29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS05695 ^@ http://purl.uniprot.org/uniprot/A0LTW9 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/351607:ACEL_RS11145 ^@ http://purl.uniprot.org/uniprot/A0LWW0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS05730 ^@ http://purl.uniprot.org/uniprot/A0LTX6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS06735 ^@ http://purl.uniprot.org/uniprot/A0LUH1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/351607:ACEL_RS07780 ^@ http://purl.uniprot.org/uniprot/A0LV21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/351607:ACEL_RS09515 ^@ http://purl.uniprot.org/uniprot/A0LW04 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/351607:ACEL_RS03295 ^@ http://purl.uniprot.org/uniprot/A0LSK3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS11075 ^@ http://purl.uniprot.org/uniprot/A0LWU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01345 ^@ http://purl.uniprot.org/uniprot/A0LRH3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/351607:ACEL_RS06515 ^@ http://purl.uniprot.org/uniprot/A0LUC7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/351607:ACEL_RS06230 ^@ http://purl.uniprot.org/uniprot/A0LU75 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/351607:ACEL_RS10090 ^@ http://purl.uniprot.org/uniprot/A0LWB5 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/351607:ACEL_RS00435 ^@ http://purl.uniprot.org/uniprot/A0LQZ8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS12370 ^@ http://purl.uniprot.org/uniprot/A0LRA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS03645 ^@ http://purl.uniprot.org/uniprot/A0LSS2 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/351607:ACEL_RS01665 ^@ http://purl.uniprot.org/uniprot/A0LRN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/351607:ACEL_RS10100 ^@ http://purl.uniprot.org/uniprot/A0LWB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01240 ^@ http://purl.uniprot.org/uniprot/A0LRF1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/351607:ACEL_RS02035 ^@ http://purl.uniprot.org/uniprot/A0LRV8 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/351607:ACEL_RS09615 ^@ http://purl.uniprot.org/uniprot/A0LW24 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/351607:ACEL_RS07020 ^@ http://purl.uniprot.org/uniprot/A0LUM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS03820 ^@ http://purl.uniprot.org/uniprot/A0LSV5 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/351607:ACEL_RS04415 ^@ http://purl.uniprot.org/uniprot/A0LT66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/351607:ACEL_RS00170 ^@ http://purl.uniprot.org/uniprot/A0LQU7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS10590 ^@ http://purl.uniprot.org/uniprot/A0LWL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/351607:ACEL_RS07970 ^@ http://purl.uniprot.org/uniprot/A0LV59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/351607:ACEL_RS06650 ^@ http://purl.uniprot.org/uniprot/A0LUF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/351607:ACEL_RS05525 ^@ http://purl.uniprot.org/uniprot/A0LTT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/351607:ACEL_RS02750 ^@ http://purl.uniprot.org/uniprot/A0LS97 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS03670 ^@ http://purl.uniprot.org/uniprot/A0LSS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS01005 ^@ http://purl.uniprot.org/uniprot/A0LRA4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/351607:ACEL_RS07585 ^@ http://purl.uniprot.org/uniprot/A0LUY5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS02685 ^@ http://purl.uniprot.org/uniprot/A0LS84 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/351607:ACEL_RS03895 ^@ http://purl.uniprot.org/uniprot/A0LSX0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/351607:ACEL_RS05940 ^@ http://purl.uniprot.org/uniprot/A0LU18 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/351607:ACEL_RS01970 ^@ http://purl.uniprot.org/uniprot/A0LRU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/351607:ACEL_RS01645 ^@ http://purl.uniprot.org/uniprot/A0LRM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS07825 ^@ http://purl.uniprot.org/uniprot/A0LV30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/351607:ACEL_RS01020 ^@ http://purl.uniprot.org/uniprot/A0LRA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05100 ^@ http://purl.uniprot.org/uniprot/A0LTK3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/351607:ACEL_RS04840 ^@ http://purl.uniprot.org/uniprot/A0LTF0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/351607:ACEL_RS02675 ^@ http://purl.uniprot.org/uniprot/A0LS82 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/351607:ACEL_RS02245 ^@ http://purl.uniprot.org/uniprot/A0LRZ7 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/351607:ACEL_RS08915 ^@ http://purl.uniprot.org/uniprot/A0LVP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/351607:ACEL_RS10290 ^@ http://purl.uniprot.org/uniprot/A0LWF5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/351607:ACEL_RS08065 ^@ http://purl.uniprot.org/uniprot/A0LV78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS05810 ^@ http://purl.uniprot.org/uniprot/A0LTZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04205 ^@ http://purl.uniprot.org/uniprot/A0LT27 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/351607:ACEL_RS09740 ^@ http://purl.uniprot.org/uniprot/A0LW49 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/351607:ACEL_RS04535 ^@ http://purl.uniprot.org/uniprot/A0LT90 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/351607:ACEL_RS06970 ^@ http://purl.uniprot.org/uniprot/A0LUL8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/351607:ACEL_RS01335 ^@ http://purl.uniprot.org/uniprot/A0LRH1 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS06235 ^@ http://purl.uniprot.org/uniprot/A0LU76 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/351607:ACEL_RS06790 ^@ http://purl.uniprot.org/uniprot/A0LUI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS11135 ^@ http://purl.uniprot.org/uniprot/A0LWV8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/351607:ACEL_RS05845 ^@ http://purl.uniprot.org/uniprot/A0LTZ9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/351607:ACEL_RS08925 ^@ http://purl.uniprot.org/uniprot/A0LVP4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/351607:ACEL_RS05435 ^@ http://purl.uniprot.org/uniprot/A0LTR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06040 ^@ http://purl.uniprot.org/uniprot/A0LU36 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/351607:ACEL_RS04150 ^@ http://purl.uniprot.org/uniprot/A0LT19 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/351607:ACEL_RS03120 ^@ http://purl.uniprot.org/uniprot/A0LSH3 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/351607:ACEL_RS06665 ^@ http://purl.uniprot.org/uniprot/A0LUF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS04495 ^@ http://purl.uniprot.org/uniprot/A0LT82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01570 ^@ http://purl.uniprot.org/uniprot/A0LRL4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/351607:ACEL_RS06160 ^@ http://purl.uniprot.org/uniprot/A0LU60 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/351607:ACEL_RS08620 ^@ http://purl.uniprot.org/uniprot/A0LVI4 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/351607:ACEL_RS07635 ^@ http://purl.uniprot.org/uniprot/A0LUZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03630 ^@ http://purl.uniprot.org/uniprot/A0LSR9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/351607:ACEL_RS03095 ^@ http://purl.uniprot.org/uniprot/A0LSG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS09510 ^@ http://purl.uniprot.org/uniprot/A0LW03 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/351607:ACEL_RS03465 ^@ http://purl.uniprot.org/uniprot/A0LSN7 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/351607:ACEL_RS05790 ^@ http://purl.uniprot.org/uniprot/A0LTY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/351607:ACEL_RS11000 ^@ http://purl.uniprot.org/uniprot/A0LWT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/351607:ACEL_RS07720 ^@ http://purl.uniprot.org/uniprot/A0LV09 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/351607:ACEL_RS07945 ^@ http://purl.uniprot.org/uniprot/A0LV54 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/351607:ACEL_RS05970 ^@ http://purl.uniprot.org/uniprot/A0LU24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01550 ^@ http://purl.uniprot.org/uniprot/A0LRL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/351607:ACEL_RS07630 ^@ http://purl.uniprot.org/uniprot/A0LUZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS10245 ^@ http://purl.uniprot.org/uniprot/A0LWE6 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS10825 ^@ http://purl.uniprot.org/uniprot/A0LWQ2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/351607:ACEL_RS07340 ^@ http://purl.uniprot.org/uniprot/A0LUT7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/351607:ACEL_RS00190 ^@ http://purl.uniprot.org/uniprot/A0LQV1 ^@ Function|||Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||May catalyze the transamination reaction in phenylalanine biosynthesis. http://togogenome.org/gene/351607:ACEL_RS03140 ^@ http://purl.uniprot.org/uniprot/P54583 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Has a very high specific activity on carboxymethylcellulose. http://togogenome.org/gene/351607:ACEL_RS00010 ^@ http://purl.uniprot.org/uniprot/A0LQR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/351607:ACEL_RS09525 ^@ http://purl.uniprot.org/uniprot/A0LW06 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/351607:ACEL_RS05510 ^@ http://purl.uniprot.org/uniprot/A0LTT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/351607:ACEL_RS02065 ^@ http://purl.uniprot.org/uniprot/A0LRW4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/351607:ACEL_RS00490 ^@ http://purl.uniprot.org/uniprot/A0LR08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/351607:ACEL_RS06730 ^@ http://purl.uniprot.org/uniprot/A0LUH0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS09090 ^@ http://purl.uniprot.org/uniprot/A0LVS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||May bind 1 zinc ion per subunit.|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/351607:ACEL_RS01720 ^@ http://purl.uniprot.org/uniprot/A0LRP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/351607:ACEL_RS11265 ^@ http://purl.uniprot.org/uniprot/A0LR57 ^@ Similarity ^@ Belongs to the neocarzinostatin family. http://togogenome.org/gene/351607:ACEL_RS00710 ^@ http://purl.uniprot.org/uniprot/A0LR50 ^@ Similarity ^@ Belongs to the glycosyl hydrolase family 6. http://togogenome.org/gene/351607:ACEL_RS03840 ^@ http://purl.uniprot.org/uniprot/A0LSV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS01235 ^@ http://purl.uniprot.org/uniprot/A0LRF0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/351607:ACEL_RS08130 ^@ http://purl.uniprot.org/uniprot/A0LV92 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/351607:ACEL_RS02830 ^@ http://purl.uniprot.org/uniprot/A0LSB3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/351607:ACEL_RS05190 ^@ http://purl.uniprot.org/uniprot/A0LTM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS03805 ^@ http://purl.uniprot.org/uniprot/A0LSV2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/351607:ACEL_RS05155 ^@ http://purl.uniprot.org/uniprot/A0LTL4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/351607:ACEL_RS07590 ^@ http://purl.uniprot.org/uniprot/A0LUY6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/351607:ACEL_RS04655 ^@ http://purl.uniprot.org/uniprot/A0LTB3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/351607:ACEL_RS03365 ^@ http://purl.uniprot.org/uniprot/A0LSL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/351607:ACEL_RS02580 ^@ http://purl.uniprot.org/uniprot/A0LS62 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/351607:ACEL_RS09760 ^@ http://purl.uniprot.org/uniprot/A0LW53 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS12355 ^@ http://purl.uniprot.org/uniprot/A0LUK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01695 ^@ http://purl.uniprot.org/uniprot/A0LRN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS01315 ^@ http://purl.uniprot.org/uniprot/A0LRG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS03205 ^@ http://purl.uniprot.org/uniprot/A0LSI7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/351607:ACEL_RS06495 ^@ http://purl.uniprot.org/uniprot/A0LUC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS03660 ^@ http://purl.uniprot.org/uniprot/A0LSS5 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/351607:ACEL_RS10265 ^@ http://purl.uniprot.org/uniprot/A0LWF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01175 ^@ http://purl.uniprot.org/uniprot/A0LRD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02410 ^@ http://purl.uniprot.org/uniprot/A0LS29 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/351607:ACEL_RS10865 ^@ http://purl.uniprot.org/uniprot/A0LWR0 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/351607:ACEL_RS09920 ^@ http://purl.uniprot.org/uniprot/A0LW84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS03485 ^@ http://purl.uniprot.org/uniprot/A0LSP1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/351607:ACEL_RS07200 ^@ http://purl.uniprot.org/uniprot/A0LUQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02535 ^@ http://purl.uniprot.org/uniprot/A0LS53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/351607:ACEL_RS02760 ^@ http://purl.uniprot.org/uniprot/A0LS99 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/351607:ACEL_RS02610 ^@ http://purl.uniprot.org/uniprot/A0LS68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01700 ^@ http://purl.uniprot.org/uniprot/A0LRP0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/351607:ACEL_RS00865 ^@ http://purl.uniprot.org/uniprot/A0LR79 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/351607:ACEL_RS03860 ^@ http://purl.uniprot.org/uniprot/A0LSW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05770 ^@ http://purl.uniprot.org/uniprot/A0LTY4 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/351607:ACEL_RS10760 ^@ http://purl.uniprot.org/uniprot/A0LWN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/351607:ACEL_RS09755 ^@ http://purl.uniprot.org/uniprot/A0LW52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06915 ^@ http://purl.uniprot.org/uniprot/A0LUK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/351607:ACEL_RS08555 ^@ http://purl.uniprot.org/uniprot/A0LVH0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/351607:ACEL_RS00835 ^@ http://purl.uniprot.org/uniprot/A0LR73 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/351607:ACEL_RS03930 ^@ http://purl.uniprot.org/uniprot/A0LSX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/351607:ACEL_RS08120 ^@ http://purl.uniprot.org/uniprot/A0LV90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/351607:ACEL_RS02205 ^@ http://purl.uniprot.org/uniprot/A0LRY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02095 ^@ http://purl.uniprot.org/uniprot/A0LRW9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS01620 ^@ http://purl.uniprot.org/uniprot/A0LRM4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/351607:ACEL_RS07125 ^@ http://purl.uniprot.org/uniprot/A0LUP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS05905 ^@ http://purl.uniprot.org/uniprot/A0LU11 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/351607:ACEL_RS10700 ^@ http://purl.uniprot.org/uniprot/A0LWM6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS05575 ^@ http://purl.uniprot.org/uniprot/A0LTU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS01850 ^@ http://purl.uniprot.org/uniprot/A0LRS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/351607:ACEL_RS00085 ^@ http://purl.uniprot.org/uniprot/A0LQT1 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/351607:ACEL_RS07120 ^@ http://purl.uniprot.org/uniprot/A0LUP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/351607:ACEL_RS06410 ^@ http://purl.uniprot.org/uniprot/A0LUA9 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/351607:ACEL_RS08095 ^@ http://purl.uniprot.org/uniprot/A0LV84 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/351607:ACEL_RS06130 ^@ http://purl.uniprot.org/uniprot/A0LU54 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/351607:ACEL_RS09000 ^@ http://purl.uniprot.org/uniprot/A0LVQ6 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/351607:ACEL_RS08050 ^@ http://purl.uniprot.org/uniprot/A0LV75 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/351607:ACEL_RS11045 ^@ http://purl.uniprot.org/uniprot/A0LWU0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/351607:ACEL_RS03475 ^@ http://purl.uniprot.org/uniprot/A0LSN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/351607:ACEL_RS01540 ^@ http://purl.uniprot.org/uniprot/A0LRK8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/351607:ACEL_RS01065 ^@ http://purl.uniprot.org/uniprot/A0LRB6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/351607:ACEL_RS00845 ^@ http://purl.uniprot.org/uniprot/A0LR75 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/351607:ACEL_RS02275 ^@ http://purl.uniprot.org/uniprot/A0LS03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06710 ^@ http://purl.uniprot.org/uniprot/A0LUG6 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/351607:ACEL_RS01480 ^@ http://purl.uniprot.org/uniprot/A0LRK0 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/351607:ACEL_RS01390 ^@ http://purl.uniprot.org/uniprot/A0LRI2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS03650 ^@ http://purl.uniprot.org/uniprot/A0LSS3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS07665 ^@ http://purl.uniprot.org/uniprot/A0LV01 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/351607:ACEL_RS08390 ^@ http://purl.uniprot.org/uniprot/A0LVE0 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/351607:ACEL_RS08875 ^@ http://purl.uniprot.org/uniprot/A0LVN5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS03740 ^@ http://purl.uniprot.org/uniprot/A0LST9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02420 ^@ http://purl.uniprot.org/uniprot/A0LS31 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/351607:ACEL_RS04320 ^@ http://purl.uniprot.org/uniprot/A0LT48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/351607:ACEL_RS06840 ^@ http://purl.uniprot.org/uniprot/A0LUJ2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS01745 ^@ http://purl.uniprot.org/uniprot/A0LRQ0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS01715 ^@ http://purl.uniprot.org/uniprot/A0LRP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/351607:ACEL_RS05640 ^@ http://purl.uniprot.org/uniprot/A0LTV8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/351607:ACEL_RS01675 ^@ http://purl.uniprot.org/uniprot/A0LRN5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/351607:ACEL_RS03250 ^@ http://purl.uniprot.org/uniprot/A0LSJ4 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/351607:ACEL_RS00265 ^@ http://purl.uniprot.org/uniprot/A0LQW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06225 ^@ http://purl.uniprot.org/uniprot/A0LU74 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/351607:ACEL_RS00875 ^@ http://purl.uniprot.org/uniprot/A0LR81 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/351607:ACEL_RS10600 ^@ http://purl.uniprot.org/uniprot/A0LWL2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/351607:ACEL_RS01610 ^@ http://purl.uniprot.org/uniprot/A0LRM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/351607:ACEL_RS11185 ^@ http://purl.uniprot.org/uniprot/A0LWW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of guanine in position 518 of 16S rRNA. http://togogenome.org/gene/351607:ACEL_RS07565 ^@ http://purl.uniprot.org/uniprot/A0LUY1 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/351607:ACEL_RS01875 ^@ http://purl.uniprot.org/uniprot/A0LRS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/351607:ACEL_RS06575 ^@ http://purl.uniprot.org/uniprot/A0LUD9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/351607:ACEL_RS03855 ^@ http://purl.uniprot.org/uniprot/A0LSW2 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/351607:ACEL_RS01130 ^@ http://purl.uniprot.org/uniprot/A0LRC9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06545 ^@ http://purl.uniprot.org/uniprot/A0LUD3 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/351607:ACEL_RS02690 ^@ http://purl.uniprot.org/uniprot/A0LS85 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/351607:ACEL_RS00995 ^@ http://purl.uniprot.org/uniprot/A0LRA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01735 ^@ http://purl.uniprot.org/uniprot/A0LRP8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/351607:ACEL_RS07930 ^@ http://purl.uniprot.org/uniprot/A0LV51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/351607:ACEL_RS09820 ^@ http://purl.uniprot.org/uniprot/A0LW64 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS02600 ^@ http://purl.uniprot.org/uniprot/A0LS66 ^@ Similarity|||Subunit ^@ Belongs to the multicopper oxidase family.|||Homotrimer. http://togogenome.org/gene/351607:ACEL_RS01865 ^@ http://purl.uniprot.org/uniprot/A0LRS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/351607:ACEL_RS06685 ^@ http://purl.uniprot.org/uniprot/A0LUG1 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/351607:ACEL_RS00700 ^@ http://purl.uniprot.org/uniprot/A0LR48 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/351607:ACEL_RS00430 ^@ http://purl.uniprot.org/uniprot/A0LQZ7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/351607:ACEL_RS00390 ^@ http://purl.uniprot.org/uniprot/A0LQY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase group 1 family. MshA subfamily.|||Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS04945 ^@ http://purl.uniprot.org/uniprot/A0LTH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/351607:ACEL_RS06355 ^@ http://purl.uniprot.org/uniprot/A0LU98 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/351607:ACEL_RS09275 ^@ http://purl.uniprot.org/uniprot/A0LVV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS00330 ^@ http://purl.uniprot.org/uniprot/A0LQX7 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/351607:ACEL_RS05180 ^@ http://purl.uniprot.org/uniprot/A0LTL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/351607:ACEL_RS10490 ^@ http://purl.uniprot.org/uniprot/A0LWJ0 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/351607:ACEL_RS06500 ^@ http://purl.uniprot.org/uniprot/A0LUC4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/351607:ACEL_RS04690 ^@ http://purl.uniprot.org/uniprot/A0LTC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS10820 ^@ http://purl.uniprot.org/uniprot/A0LWQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS00585 ^@ http://purl.uniprot.org/uniprot/A0LR27 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/351607:ACEL_RS07730 ^@ http://purl.uniprot.org/uniprot/A0LV11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS10070 ^@ http://purl.uniprot.org/uniprot/A0LWB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/351607:ACEL_RS07800 ^@ http://purl.uniprot.org/uniprot/A0LV25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/351607:ACEL_RS11715 ^@ http://purl.uniprot.org/uniprot/A0LWE8 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/351607:ACEL_RS05805 ^@ http://purl.uniprot.org/uniprot/A0LTZ1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/351607:ACEL_RS08260 ^@ http://purl.uniprot.org/uniprot/A0LVB6 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/351607:ACEL_RS00340 ^@ http://purl.uniprot.org/uniprot/A0LQX9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS01410 ^@ http://purl.uniprot.org/uniprot/A0LRI6 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/351607:ACEL_RS07085 ^@ http://purl.uniprot.org/uniprot/A0LUN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS08230 ^@ http://purl.uniprot.org/uniprot/A0LVB0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/351607:ACEL_RS06490 ^@ http://purl.uniprot.org/uniprot/A0LUC2 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/351607:ACEL_RS01080 ^@ http://purl.uniprot.org/uniprot/A0LRB9 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/351607:ACEL_RS08040 ^@ http://purl.uniprot.org/uniprot/A0LV73 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/351607:ACEL_RS09625 ^@ http://purl.uniprot.org/uniprot/A0LW26 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/351607:ACEL_RS04940 ^@ http://purl.uniprot.org/uniprot/A0LTH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05745 ^@ http://purl.uniprot.org/uniprot/A0LTX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS03570 ^@ http://purl.uniprot.org/uniprot/A0LSQ7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/351607:ACEL_RS11270 ^@ http://purl.uniprot.org/uniprot/A0LR60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS11005 ^@ http://purl.uniprot.org/uniprot/A0LWT2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/351607:ACEL_RS08180 ^@ http://purl.uniprot.org/uniprot/A0LVA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/351607:ACEL_RS00840 ^@ http://purl.uniprot.org/uniprot/A0LR74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/351607:ACEL_RS01430 ^@ http://purl.uniprot.org/uniprot/A0LRJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS09700 ^@ http://purl.uniprot.org/uniprot/A0LW41 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/351607:ACEL_RS06475 ^@ http://purl.uniprot.org/uniprot/A0LUB9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/351607:ACEL_RS01405 ^@ http://purl.uniprot.org/uniprot/A0LRI5 ^@ Similarity ^@ Belongs to the complex I 24 kDa subunit family. http://togogenome.org/gene/351607:ACEL_RS06725 ^@ http://purl.uniprot.org/uniprot/A0LUG9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS00815 ^@ http://purl.uniprot.org/uniprot/A0LR69 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/351607:ACEL_RS01250 ^@ http://purl.uniprot.org/uniprot/A0LRF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/351607:ACEL_RS07770 ^@ http://purl.uniprot.org/uniprot/A0LV19 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/351607:ACEL_RS07795 ^@ http://purl.uniprot.org/uniprot/A0LV24 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/351607:ACEL_RS06625 ^@ http://purl.uniprot.org/uniprot/A0LUE9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/351607:ACEL_RS06530 ^@ http://purl.uniprot.org/uniprot/A0LUD0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/351607:ACEL_RS07920 ^@ http://purl.uniprot.org/uniprot/A0LV49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS06675 ^@ http://purl.uniprot.org/uniprot/A0LUF9 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/351607:ACEL_RS10015 ^@ http://purl.uniprot.org/uniprot/A0LWA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS03585 ^@ http://purl.uniprot.org/uniprot/A0LSR0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/351607:ACEL_RS05345 ^@ http://purl.uniprot.org/uniprot/A0LTQ1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/351607:ACEL_RS08625 ^@ http://purl.uniprot.org/uniprot/A0LVI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS06080 ^@ http://purl.uniprot.org/uniprot/A0LU44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/351607:ACEL_RS07905 ^@ http://purl.uniprot.org/uniprot/A0LV46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS02180 ^@ http://purl.uniprot.org/uniprot/A0LRY5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/351607:ACEL_RS02770 ^@ http://purl.uniprot.org/uniprot/A0LSA1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/351607:ACEL_RS11065 ^@ http://purl.uniprot.org/uniprot/A0LWU4 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS00620 ^@ http://purl.uniprot.org/uniprot/A0LR34 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/351607:ACEL_RS04530 ^@ http://purl.uniprot.org/uniprot/A0LT89 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS01880 ^@ http://purl.uniprot.org/uniprot/A0LRS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/351607:ACEL_RS00005 ^@ http://purl.uniprot.org/uniprot/A0LQR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/351607:ACEL_RS01445 ^@ http://purl.uniprot.org/uniprot/A0LRJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS05795 ^@ http://purl.uniprot.org/uniprot/A0LTY9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS05075 ^@ http://purl.uniprot.org/uniprot/A0LTJ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/351607:ACEL_RS06485 ^@ http://purl.uniprot.org/uniprot/A0LUC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/351607:ACEL_RS05505 ^@ http://purl.uniprot.org/uniprot/A0LTT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/351607:ACEL_RS03905 ^@ http://purl.uniprot.org/uniprot/A0LSX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/351607:ACEL_RS04515 ^@ http://purl.uniprot.org/uniprot/A0LT86 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/351607:ACEL_RS07075 ^@ http://purl.uniprot.org/uniprot/A0LUN4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/351607:ACEL_RS00600 ^@ http://purl.uniprot.org/uniprot/A0LR30 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS10780 ^@ http://purl.uniprot.org/uniprot/A0LWP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS04750 ^@ http://purl.uniprot.org/uniprot/A0LTD2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/351607:ACEL_RS01425 ^@ http://purl.uniprot.org/uniprot/A0LRI9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/351607:ACEL_RS06560 ^@ http://purl.uniprot.org/uniprot/A0LUD6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/351607:ACEL_RS03085 ^@ http://purl.uniprot.org/uniprot/A0LSG6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/351607:ACEL_RS05690 ^@ http://purl.uniprot.org/uniprot/A0LTW8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/351607:ACEL_RS01325 ^@ http://purl.uniprot.org/uniprot/A0LRG9 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/351607:ACEL_RS05330 ^@ http://purl.uniprot.org/uniprot/A0LTP7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/351607:ACEL_RS08545 ^@ http://purl.uniprot.org/uniprot/A0LVG8 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/351607:ACEL_RS06060 ^@ http://purl.uniprot.org/uniprot/A0LU40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS07820 ^@ http://purl.uniprot.org/uniprot/A0LV29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/351607:ACEL_RS05835 ^@ http://purl.uniprot.org/uniprot/A0LTZ7 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/351607:ACEL_RS04715 ^@ http://purl.uniprot.org/uniprot/A0LTC5 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/351607:ACEL_RS09775 ^@ http://purl.uniprot.org/uniprot/A0LW56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS05750 ^@ http://purl.uniprot.org/uniprot/A0LTY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS04420 ^@ http://purl.uniprot.org/uniprot/A0LT67 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS08845 ^@ http://purl.uniprot.org/uniprot/A0LVM7 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/351607:ACEL_RS04855 ^@ http://purl.uniprot.org/uniprot/A0LTF3 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/351607:ACEL_RS05500 ^@ http://purl.uniprot.org/uniprot/A0LTT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/351607:ACEL_RS09795 ^@ http://purl.uniprot.org/uniprot/A0LW60 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/351607:ACEL_RS05580 ^@ http://purl.uniprot.org/uniprot/A0LTU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS00825 ^@ http://purl.uniprot.org/uniprot/A0LR71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscL family.|||Membrane http://togogenome.org/gene/351607:ACEL_RS01505 ^@ http://purl.uniprot.org/uniprot/A0LRK2 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/351607:ACEL_RS06390 ^@ http://purl.uniprot.org/uniprot/A0LUA5 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/351607:ACEL_RS01965 ^@ http://purl.uniprot.org/uniprot/A0LRU4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/351607:ACEL_RS01635 ^@ http://purl.uniprot.org/uniprot/A0LRM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/351607:ACEL_RS04790 ^@ http://purl.uniprot.org/uniprot/A0LTE0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/351607:ACEL_RS11205 ^@ http://purl.uniprot.org/uniprot/A0LWX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/351607:ACEL_RS10460 ^@ http://purl.uniprot.org/uniprot/A0LWI4 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/351607:ACEL_RS09680 ^@ http://purl.uniprot.org/uniprot/A0LW37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/351607:ACEL_RS03845 ^@ http://purl.uniprot.org/uniprot/A0LSW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/351607:ACEL_RS08900 ^@ http://purl.uniprot.org/uniprot/A0LVP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/351607:ACEL_RS11050 ^@ http://purl.uniprot.org/uniprot/A0LWU1 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/351607:ACEL_RS03110 ^@ http://purl.uniprot.org/uniprot/A0LSH1 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/351607:ACEL_RS12235 ^@ http://purl.uniprot.org/uniprot/A0LSJ9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS08320 ^@ http://purl.uniprot.org/uniprot/A0LVC6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/351607:ACEL_RS01790 ^@ http://purl.uniprot.org/uniprot/A0LRQ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS04830 ^@ http://purl.uniprot.org/uniprot/A0LTE8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/351607:ACEL_RS07750 ^@ http://purl.uniprot.org/uniprot/A0LV15 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/351607:ACEL_RS05920 ^@ http://purl.uniprot.org/uniprot/A0LU14 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/351607:ACEL_RS00165 ^@ http://purl.uniprot.org/uniprot/A0LQU6 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/351607:ACEL_RS06275 ^@ http://purl.uniprot.org/uniprot/A0LU83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/351607:ACEL_RS12705 ^@ http://purl.uniprot.org/uniprot/A0LWH9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/351607:ACEL_RS04965 ^@ http://purl.uniprot.org/uniprot/A0LTH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/351607:ACEL_RS06305 ^@ http://purl.uniprot.org/uniprot/A0LU89 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/351607:ACEL_RS06645 ^@ http://purl.uniprot.org/uniprot/A0LUF3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/351607:ACEL_RS08685 ^@ http://purl.uniprot.org/uniprot/A0LVJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/351607:ACEL_RS04370 ^@ http://purl.uniprot.org/uniprot/A0LT57 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/351607:ACEL_RS07035 ^@ http://purl.uniprot.org/uniprot/A0LUN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/351607:ACEL_RS01205 ^@ http://purl.uniprot.org/uniprot/A0LRE4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/351607:ACEL_RS07265 ^@ http://purl.uniprot.org/uniprot/A0LUS2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/351607:ACEL_RS03900 ^@ http://purl.uniprot.org/uniprot/A0LSX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/351607:ACEL_RS02880 ^@ http://purl.uniprot.org/uniprot/A0LSC3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/351607:ACEL_RS11030 ^@ http://purl.uniprot.org/uniprot/A0LWT7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/351607:ACEL_RS10845 ^@ http://purl.uniprot.org/uniprot/A0LWQ6 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/351607:ACEL_RS12460 ^@ http://purl.uniprot.org/uniprot/A0LVL3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 9 (cellulase E) family. http://togogenome.org/gene/351607:ACEL_RS04970 ^@ http://purl.uniprot.org/uniprot/A0LTH6 ^@ Caution|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/351607:ACEL_RS08145 ^@ http://purl.uniprot.org/uniprot/A0LV95 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.