http://togogenome.org/gene/361101:EL147_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZAR9 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/361101:EL147_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A4U9YD19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/361101:EL147_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A4V6L242 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A4V6L0I1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/361101:EL147_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIH3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/361101:EL147_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKK2 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/361101:EL147_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A4U9YBF7 ^@ Similarity ^@ Belongs to the UPF0223 family. http://togogenome.org/gene/361101:EL147_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/361101:EL147_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A4V6L2R6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/361101:EL147_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A4V6L6T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/361101:EL147_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZII0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/361101:EL147_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A4V6L066 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/361101:EL147_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A4U9XYG3 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/361101:EL147_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZAG7 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/361101:EL147_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM20 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/361101:EL147_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJ38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/361101:EL147_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJG0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/361101:EL147_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZRU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A4U9YGY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A4U9XVS1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A4U9YY61 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/361101:EL147_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A4U9YCJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y3V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/361101:EL147_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A4V6L1G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/361101:EL147_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLH5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/361101:EL147_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJZ4 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/361101:EL147_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A4U9Z021 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/361101:EL147_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y6A6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/361101:EL147_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A4U9YIG9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/361101:EL147_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A4V6L0T8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A4V6Z3P7 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/361101:EL147_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A4V6KZB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/361101:EL147_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLU2 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/361101:EL147_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A4U9XII0 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/361101:EL147_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/361101:EL147_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKS8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/361101:EL147_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/361101:EL147_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZA76 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PPase class C family.|||Binds 2 manganese ions per subunit.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A4U9YEI9 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/361101:EL147_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A4U9YM28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A4V6L7X9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/361101:EL147_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJI5 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/361101:EL147_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKE9 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/361101:EL147_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A4U9XL48 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/361101:EL147_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A4U9Z5R5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZRP7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/361101:EL147_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A4U9YZ17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HPr family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.|||P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity. http://togogenome.org/gene/361101:EL147_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A4U9YBE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQI2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/361101:EL147_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y2K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GpsB family.|||Cytoplasm|||Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.|||Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA. http://togogenome.org/gene/361101:EL147_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A4U9XY30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/361101:EL147_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A4U9YJC2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A4U9YFC5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/361101:EL147_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A4U9XW92 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/361101:EL147_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJX2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/361101:EL147_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKN3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/361101:EL147_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZCZ6 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/361101:EL147_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/361101:EL147_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A4U9XK23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/361101:EL147_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A4U9XTV1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/361101:EL147_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A4U9XT35 ^@ Function ^@ Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. http://togogenome.org/gene/361101:EL147_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/361101:EL147_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y0K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/361101:EL147_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/361101:EL147_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A4U9XK35 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZPR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZIU9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/361101:EL147_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A4U9XK62 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/361101:EL147_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZTR8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/361101:EL147_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A4U9Z8J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/361101:EL147_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A4U9YBU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y7D0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZAE3 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/361101:EL147_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A4U9XI74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y485 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/361101:EL147_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZBX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0154 family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZEK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/361101:EL147_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A4V6L1J3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/361101:EL147_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJ32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM30 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/361101:EL147_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A4U9XN59 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/361101:EL147_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/361101:EL147_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y1B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. http://togogenome.org/gene/361101:EL147_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A4U9XN84 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/361101:EL147_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A4V6L0D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A4U9XL66 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/361101:EL147_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A4U9XME4 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/361101:EL147_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/361101:EL147_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A4U9XTV0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/361101:EL147_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A4U9YQI9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A4V6L077 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/361101:EL147_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A4U9YUM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/361101:EL147_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIB5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/361101:EL147_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A4V6Z3X7 ^@ Similarity|||Subunit ^@ Belongs to the UPF0237 family.|||Homodimer. http://togogenome.org/gene/361101:EL147_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQ53 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/361101:EL147_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A4V6L1H1 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/361101:EL147_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZE43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family. YeeN subfamily.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/361101:EL147_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y978 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/361101:EL147_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A4V6L0B5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/361101:EL147_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y8K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/361101:EL147_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A4U9YKQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/361101:EL147_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/361101:EL147_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A4U9YHB8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/361101:EL147_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A4V6Z3V9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/361101:EL147_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHX0 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/361101:EL147_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A4U9XMX7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/361101:EL147_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A4V6L277 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/361101:EL147_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A4U9YHE5 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/361101:EL147_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A4U9XRU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/361101:EL147_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A4U9YDR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A4U9YBC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/361101:EL147_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZH09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/361101:EL147_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/361101:EL147_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKF1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/361101:EL147_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A4U9XRA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A4U9XP89 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZFJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/361101:EL147_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQN7 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/361101:EL147_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A4U9XI10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A4U9XU05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/361101:EL147_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/361101:EL147_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A4U9YAN9 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/361101:EL147_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A4U9XPH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/361101:EL147_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQ12 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/361101:EL147_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A4U9YF47 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/361101:EL147_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A4U9XVY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/361101:EL147_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/361101:EL147_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZUB5 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/361101:EL147_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y8K4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/361101:EL147_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A4U9YL55 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/361101:EL147_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi. http://togogenome.org/gene/361101:EL147_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/361101:EL147_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJN6 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/361101:EL147_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A4U9YHT2 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/361101:EL147_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A4U9YV21 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/361101:EL147_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A4U9YJ71 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/361101:EL147_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y6N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y3I8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/361101:EL147_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A4U9XPM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/361101:EL147_RS07350 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y9P7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/361101:EL147_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A4U9XPJ7 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/361101:EL147_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y9T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/361101:EL147_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/361101:EL147_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIX7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/361101:EL147_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A4U9YCN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/361101:EL147_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A4V6L4E5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A4U9XMA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/361101:EL147_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLB7 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/361101:EL147_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A4V6KZU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/361101:EL147_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIQ2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/361101:EL147_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A4U9Z1V0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/361101:EL147_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A4U9XUI3 ^@ Similarity ^@ Belongs to the UPF0346 family. http://togogenome.org/gene/361101:EL147_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A4U9XL88 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/361101:EL147_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZDJ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/361101:EL147_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A4V6L319 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKV4 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/361101:EL147_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A4U9YBZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGL0 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/361101:EL147_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A4U9XRN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/361101:EL147_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A4U9YFS0 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/361101:EL147_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKH0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y2F8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/361101:EL147_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y9J5 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/361101:EL147_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIK4 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A4U9YV28 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/361101:EL147_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A4U9XMK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/361101:EL147_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y491 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A4V6L025 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/361101:EL147_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHV7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/361101:EL147_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A4U9XGM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/361101:EL147_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A4U9YFB8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/361101:EL147_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/361101:EL147_RS08870 ^@ http://purl.uniprot.org/uniprot/A0A4U9XXH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/361101:EL147_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y8Y6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/361101:EL147_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y5T1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A4V0HAL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/361101:EL147_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/361101:EL147_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A4U9XZ93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/361101:EL147_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A4U9XRZ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/361101:EL147_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A4V6KZG2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/361101:EL147_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A4U9YHB2 ^@ Function|||Similarity ^@ Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. http://togogenome.org/gene/361101:EL147_RS07115 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLG7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/361101:EL147_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A4V6L298 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArsC family. Spx subfamily.|||Cytoplasm|||Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.|||Interacts with the C-terminal domain of the alpha subunit of the RNAP. http://togogenome.org/gene/361101:EL147_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIP4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/361101:EL147_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A4U9YJT1 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/361101:EL147_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/361101:EL147_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKD7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A4U9Z6C6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/361101:EL147_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A4U9XQR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/361101:EL147_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y0H9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A4V6L2X9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/361101:EL147_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A4U9XM75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A4U9XPF3 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/361101:EL147_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A4V6Z3T1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/361101:EL147_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJ04 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/361101:EL147_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A4U9XPP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/361101:EL147_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A4V6Z425 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/361101:EL147_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZGI3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/361101:EL147_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/361101:EL147_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKR7 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/361101:EL147_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y8X0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/361101:EL147_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZQ44 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/361101:EL147_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A4U9XXF7 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/361101:EL147_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A4U9XLT6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/361101:EL147_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZN64 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/361101:EL147_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A4U9XII3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RpoE family.|||Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors. http://togogenome.org/gene/361101:EL147_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y6V4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 73 family. http://togogenome.org/gene/361101:EL147_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y694 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/361101:EL147_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/361101:EL147_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/361101:EL147_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A4U9XYX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/361101:EL147_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A4U9XMM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/361101:EL147_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A4U9YJB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/361101:EL147_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A4U9XJS1 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/361101:EL147_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y804 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/361101:EL147_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A4U9XMV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/361101:EL147_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A4U9XHM5 ^@ Similarity ^@ Belongs to the UPF0374 family. http://togogenome.org/gene/361101:EL147_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZHP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/361101:EL147_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A4U9XIW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/361101:EL147_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y2N4 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/361101:EL147_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A4U9XUC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/361101:EL147_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A4V6KZL9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/361101:EL147_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A4U9XL99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/361101:EL147_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A4U9XP72 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/361101:EL147_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A4U9ZB65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0298 family.|||Cytoplasm http://togogenome.org/gene/361101:EL147_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A4U9XZN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/361101:EL147_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A4U9XND1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/361101:EL147_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A4U9YCH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/361101:EL147_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A4U9Y3S1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/361101:EL147_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A4U9XKG1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer.