http://togogenome.org/gene/36874:EL262_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A099WTB5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/36874:EL262_RS09780 ^@ http://purl.uniprot.org/uniprot/A0A1T4NA27 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/36874:EL262_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A1T4K307 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A1T4KWY8 ^@ Similarity ^@ Belongs to the IPP isomerase type 1 family. http://togogenome.org/gene/36874:EL262_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A0A2EW38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/36874:EL262_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A1T4JR83 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/36874:EL262_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A0A2EPM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/36874:EL262_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A1T4JX20 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/36874:EL262_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A1T4KRT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/36874:EL262_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A1T4NL33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A099WXI9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/36874:EL262_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A099WV07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/36874:EL262_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A099WSJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/36874:EL262_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A0A2ELW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/36874:EL262_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A099WZZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/36874:EL262_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A1T4KNA2 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/36874:EL262_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A099WTF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/36874:EL262_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A1T4KB75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07200 ^@ http://purl.uniprot.org/uniprot/A0A1T4MXP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/36874:EL262_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0A2EW51 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/36874:EL262_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A099WUM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/36874:EL262_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A099WTS4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/36874:EL262_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A1T4LU23 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/36874:EL262_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4S6 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/36874:EL262_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A1T4KPU2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/36874:EL262_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A099WTL2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/36874:EL262_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A1T4NS01 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/36874:EL262_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A1T4MUQ4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/36874:EL262_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A099WUZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/36874:EL262_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A1T4MDQ0 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/36874:EL262_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A1T4LBE0 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/36874:EL262_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPD0 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/36874:EL262_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPP2 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/36874:EL262_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A1T4N7M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/36874:EL262_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A099WX33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/36874:EL262_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A099WSK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A1T4N9A2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/36874:EL262_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A099WZB3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A0A2EJZ2 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/36874:EL262_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A099WXW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A1T4M950 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A0A2ENK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/36874:EL262_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/36874:EL262_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A1T4JS57 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/36874:EL262_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A1T4P194 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/36874:EL262_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A1T4MFI7 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/36874:EL262_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A1T4KQE8 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/36874:EL262_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A099WYZ8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A099WZE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A099WTR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A1T4N8F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A1T4MW05 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09820 ^@ http://purl.uniprot.org/uniprot/A0A099WSR3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A1T4LM79 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/36874:EL262_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A099WWD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/36874:EL262_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A1T4MCB7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A099WZC3 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/36874:EL262_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A1T4NNW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A1T4JML2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/36874:EL262_RS00100 ^@ http://purl.uniprot.org/uniprot/A0A1T4MUQ5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/36874:EL262_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A099WYP8 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/36874:EL262_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A099WT97 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/36874:EL262_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A1T4K050 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/36874:EL262_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A0A2ETP9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/36874:EL262_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A1T4M8E4 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/36874:EL262_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A0A2EWB8 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/36874:EL262_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNS2 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/36874:EL262_RS04395 ^@ http://purl.uniprot.org/uniprot/A0A1T4K1Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A099WSA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A1T4K0N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/36874:EL262_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A1T4NFT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A099WQU1 ^@ Caution|||Subcellular Location Annotation ^@ Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A099WVG3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/36874:EL262_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A1T4MBN4 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A1T4MEA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/36874:EL262_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A1T4LMQ6 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/36874:EL262_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A099WQR1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS06090 ^@ http://purl.uniprot.org/uniprot/A0A1T4L5V3 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/36874:EL262_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQ42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/36874:EL262_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A1T4L0T4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/36874:EL262_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A099WTB8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/36874:EL262_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A1T4LY19 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/36874:EL262_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A0A2EQM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/36874:EL262_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A099WTH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/36874:EL262_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A1T4JP74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/36874:EL262_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLZ1 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A099WZ48 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/36874:EL262_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A1T4KI27 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBM7 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/36874:EL262_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPP4 ^@ Similarity ^@ Belongs to the AIR synthase family. http://togogenome.org/gene/36874:EL262_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4H7 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/36874:EL262_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A0A2EPT2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/36874:EL262_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A099WY94 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A1T4MIP3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/36874:EL262_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A099WWQ7 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/36874:EL262_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A1T4MZ34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/36874:EL262_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A099WUY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A0A2EVI8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A1T4JPS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A099WTG9 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/36874:EL262_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A099WTW6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/36874:EL262_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A1T4K538 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/36874:EL262_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A1T4JPM7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/36874:EL262_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A099WUJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/36874:EL262_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A1T4NDZ3 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/36874:EL262_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A099WSA1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrC family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/36874:EL262_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A099WWW7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A1T4JSD2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/36874:EL262_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A1T4MI00 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A1T4NC98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A1T4KCL5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/36874:EL262_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A1T4N3Z3 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/36874:EL262_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A099WVU3 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/36874:EL262_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A099WYJ1 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/36874:EL262_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0A2EXY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/36874:EL262_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A0A2EKU9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxC family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/36874:EL262_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A1T4JZA3 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/36874:EL262_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A1T4M6D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A1T4MXH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/36874:EL262_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A099WV88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/36874:EL262_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A099WT77 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A099WTT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/36874:EL262_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family.|||Cell outer membrane|||Fimbrium|||Membrane http://togogenome.org/gene/36874:EL262_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A1T4K2N4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/36874:EL262_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A099WPQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/36874:EL262_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A0A2EVF2 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/36874:EL262_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A099WTK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/36874:EL262_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A1T4L0N1 ^@ Similarity ^@ Belongs to the XseB family. http://togogenome.org/gene/36874:EL262_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A1T4KGG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/36874:EL262_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A0A2EST7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A1T4KZZ7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/36874:EL262_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A1T4L4D6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/36874:EL262_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A1T4MDT6 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/36874:EL262_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A099WXM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/36874:EL262_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A1T4MIQ4 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/36874:EL262_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A099WZA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/36874:EL262_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A1T4JZ75 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/36874:EL262_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBR4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/36874:EL262_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A1T4KQ26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/36874:EL262_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A1T4M759 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A1T4JMD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A1T4KDB0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/36874:EL262_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A099WX78 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A1T4JPK1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/36874:EL262_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A099X134 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/36874:EL262_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9N8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/36874:EL262_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A099WUA3 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/36874:EL262_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A099WTY0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A1T4NPY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A1T4MW46 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/36874:EL262_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A1T4MK34 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A1T4LWQ5 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/36874:EL262_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A1T4K2K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/36874:EL262_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A1T4JZ64 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/36874:EL262_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9R2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/36874:EL262_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A1T4K611 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/36874:EL262_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A0A2EMC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A1T4LGT1 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/36874:EL262_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A1T4KP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A1T4KLN2 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/36874:EL262_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A1T4M7U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A099WRW1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/36874:EL262_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A0A2EYE8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A1T4LWV2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A099WTX1 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/36874:EL262_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A1T4KNV9 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/36874:EL262_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A1T4KSP9 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/36874:EL262_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A1T4MI78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/36874:EL262_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A1T4M809 ^@ Similarity ^@ In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/36874:EL262_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A1T4JMS9 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/36874:EL262_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A1T4JPS9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A1T4K121 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9T2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A099WWM8 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/36874:EL262_RS08085 ^@ http://purl.uniprot.org/uniprot/A0A099WVT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0A2EY50 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A099WTH8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A099WTH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A099WX56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/36874:EL262_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A0A2EZR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A1T4MUQ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/36874:EL262_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A099WWS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/36874:EL262_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A099WZG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/36874:EL262_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A1T4MD94 ^@ Function ^@ Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/36874:EL262_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A1T4KMQ0 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A1T4JZI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A099WSU6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A1T4LXC5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/36874:EL262_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A1T4LJW2 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A099WTU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/36874:EL262_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A1T4NFN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A099WYZ2 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/36874:EL262_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A1T4M386 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/36874:EL262_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A1T4L4W6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/36874:EL262_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A099X0J7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/36874:EL262_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A0A2EWA0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A099WS62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/36874:EL262_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A1T4LS38 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/36874:EL262_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A099WZ72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/36874:EL262_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0A2EKX6 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/36874:EL262_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/36874:EL262_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A1T4L0W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XseA family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A1T4KE41 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/36874:EL262_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A0A2EZX1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A1T4MXV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/36874:EL262_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A099WQK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A1T4MSH7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/36874:EL262_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A1T4NR66 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A1T4JW98 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/36874:EL262_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A1T4N6G8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/36874:EL262_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A099WXF5 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/36874:EL262_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A1T4MND0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A1T4LG32 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/36874:EL262_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A099WT85 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/36874:EL262_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A1T4LZH6 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/36874:EL262_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A1T4MNL2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A099WQV4 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/36874:EL262_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4M2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Fimbrium|||Membrane http://togogenome.org/gene/36874:EL262_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A099WXX3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/36874:EL262_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLM4 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/36874:EL262_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A099WTA4 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/36874:EL262_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9J6 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/36874:EL262_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A1T4NWN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/36874:EL262_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A0A2ES79 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/36874:EL262_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A099WP02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/36874:EL262_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A1T4MTA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/36874:EL262_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A1T4JRE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/36874:EL262_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A1T4KZL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A0A2EM28 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A1T4M8C4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A1T4K480 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/36874:EL262_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A099X108 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/36874:EL262_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A099WQ18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A1T4K181 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A1T4KRY8 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/36874:EL262_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A1T4LQM1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/36874:EL262_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A099WYW7 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A099WUU5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/36874:EL262_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A099WS43 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/36874:EL262_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A1T4N7Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A1T4M768 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A099WW17 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/36874:EL262_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A1T4NXB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/36874:EL262_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A1T4KQQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the precorrin methyltransferase family.|||Homodimer.|||Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. http://togogenome.org/gene/36874:EL262_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A1T4MSY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/36874:EL262_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A0A2EM62 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/36874:EL262_RS05875 ^@ http://purl.uniprot.org/uniprot/A0A1T4M1Q5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/36874:EL262_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A0A2ENV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/36874:EL262_RS07195 ^@ http://purl.uniprot.org/uniprot/A0A099WVR6 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/36874:EL262_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A099WQ25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/36874:EL262_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A0A2EVM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/36874:EL262_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A1T4JM38 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/36874:EL262_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A1T4LNZ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/36874:EL262_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A0A2EVW0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A1T4L4C4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A1T4NYX9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A1T4N3C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A1T4LXD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylmalonyl-CoA mutase family.|||Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/36874:EL262_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A099WXM4 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/36874:EL262_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A1T4JME0 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/36874:EL262_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A099WTI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/36874:EL262_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A099WUI2 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A1T4KN18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/36874:EL262_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A1T4KSI6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A099WT51 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/36874:EL262_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A1T4JS37 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/36874:EL262_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A1T4LKL4 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/36874:EL262_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A099WZ12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/36874:EL262_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A1T4LM72 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/36874:EL262_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A1T4JXM7 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A1T4K3Q7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/36874:EL262_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A1T4N1J9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/36874:EL262_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A1T4L127 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/36874:EL262_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A1T4KBL0 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/36874:EL262_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A1T4KZZ5 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/36874:EL262_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A099WXS9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/36874:EL262_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A1T4LXU0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/36874:EL262_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A1T4LFV4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/36874:EL262_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A1T4MIS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A1T4M874 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/36874:EL262_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A1T4JL35 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/36874:EL262_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A099WSM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/36874:EL262_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A1T4LWC8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A1T4L137 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/36874:EL262_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A1T4JT17 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/36874:EL262_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A1T4KD98 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/36874:EL262_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A1T4KS39 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/36874:EL262_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A099X0A6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/36874:EL262_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A099WSL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A1T4K5X1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/36874:EL262_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A099WTV6 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/36874:EL262_RS01820 ^@ http://purl.uniprot.org/uniprot/A0A1T4MA43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A1T4MTP7 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/36874:EL262_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQD2 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/36874:EL262_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A099WUZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/36874:EL262_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A0A2ES84 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/36874:EL262_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A1T4M6V4 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/36874:EL262_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A1T4MXQ4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9C9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A099WXC7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A1T4K2B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/36874:EL262_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A1T4JYP6 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/36874:EL262_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A1T4JYY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/36874:EL262_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A099WXH7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/36874:EL262_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A0A2EM49 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS05570 ^@ http://purl.uniprot.org/uniprot/A0A099WV03 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/36874:EL262_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A1T4MZF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/36874:EL262_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A1T4MRZ5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/36874:EL262_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A1T4K5V0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/36874:EL262_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A1T4JPD5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/36874:EL262_RS09765 ^@ http://purl.uniprot.org/uniprot/A0A1T4NB76 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/36874:EL262_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A1T4LGT2 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A0A2EYA7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A099WYI8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/36874:EL262_RS04240 ^@ http://purl.uniprot.org/uniprot/A0A1T4K0A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A1T4L0H2 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/36874:EL262_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A1T4KP49 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/36874:EL262_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A1T4K3J0 ^@ Similarity ^@ Belongs to the peptidase C25 family.|||Belongs to the peptidase S8 family. http://togogenome.org/gene/36874:EL262_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A1T4MCT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/36874:EL262_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A1T4MC36 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/36874:EL262_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A1T4NK33 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A099WT21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/36874:EL262_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A099WZ45 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/36874:EL262_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A099X1F9 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/36874:EL262_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A0A2EQX9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/36874:EL262_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A099WW62 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/36874:EL262_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/36874:EL262_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A1T4LKF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A1T4NUR7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/36874:EL262_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0A2EVL8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/36874:EL262_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A099X000 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/36874:EL262_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A1T4KQJ2 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/36874:EL262_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A099WUR2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A1T4N5U4 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/36874:EL262_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A1T4NR29 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A099X0F4 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/36874:EL262_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A099WZ83 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/36874:EL262_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A099WV01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/36874:EL262_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A1T4LK57 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/36874:EL262_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A1T4LGZ8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/36874:EL262_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A1T4N3R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A099WXK3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/36874:EL262_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A099WWA8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A0A2EQW9 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/36874:EL262_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A0A2EN89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/36874:EL262_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A099WU80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/36874:EL262_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A1T4LNT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/36874:EL262_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A1T4LZX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/36874:EL262_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A099WUI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A1T4M671 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/36874:EL262_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A1T4K5V7 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/36874:EL262_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4L6 ^@ Similarity ^@ Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family. http://togogenome.org/gene/36874:EL262_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A1T4LKJ7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/36874:EL262_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A1T4KSB9 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/36874:EL262_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A1T4JRB7 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A0A2ERI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/36874:EL262_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A0A2ESU8 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/36874:EL262_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A099WND7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A0A2EPW6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A1T4N8Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/36874:EL262_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A1T4JKP6 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A099WU84 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A1T4N6J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A1T4K6T5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/36874:EL262_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A1T4JT22 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/36874:EL262_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A1T4MA99 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/36874:EL262_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A1T4NFU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A1T4LSJ9 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/36874:EL262_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A099WTI3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/36874:EL262_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A1T4KCK3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/36874:EL262_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A1T4M937 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A1T4JY94 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/36874:EL262_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A0A2EU52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/36874:EL262_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A099WPM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/36874:EL262_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A099WPL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A1T4KAT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm|||Degrades oligopeptides. http://togogenome.org/gene/36874:EL262_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A099WYL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/36874:EL262_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A099WYU5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/36874:EL262_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A1T4KCF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A1T4NB02 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/36874:EL262_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A099WQ11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/36874:EL262_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A0A2EJB8 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/36874:EL262_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A1T4NAV1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A099WRY2 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/36874:EL262_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A099WXS0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/36874:EL262_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A1T4L276 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/36874:EL262_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A1T4KDL7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4Q5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Fimbrium|||Membrane http://togogenome.org/gene/36874:EL262_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A1T4KC16 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/36874:EL262_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A099WUD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A1T4LUP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/36874:EL262_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A0A2ENU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/36874:EL262_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A1T4KD55 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/36874:EL262_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A1T4NYK9 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/36874:EL262_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A099X1B9 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/36874:EL262_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A099X039 ^@ Caution|||Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A1T4MU67 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A0A2EWF8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPL8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/36874:EL262_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A1T4NZ17 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/36874:EL262_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A1T4MKM3 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/36874:EL262_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A099WTI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/36874:EL262_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A099X061 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/36874:EL262_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A099WX49 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/36874:EL262_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A1T4NL54 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/36874:EL262_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A099WTH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/36874:EL262_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A1T4JXL5 ^@ Similarity ^@ Belongs to the NusB family. http://togogenome.org/gene/36874:EL262_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A1T4LXJ2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A099WUV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0A2EP67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/36874:EL262_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A099WWE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/36874:EL262_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A099WSR2 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/36874:EL262_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A1T4L581 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A1T4JXV3 ^@ Similarity ^@ Belongs to the peptidase C25 family. http://togogenome.org/gene/36874:EL262_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A1T4K2Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A099WUT6 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/36874:EL262_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A0A2ETD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/36874:EL262_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/36874:EL262_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A1T4M8R8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A1T4JYG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/36874:EL262_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A1T4KCM4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/36874:EL262_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A1T4KDB5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A1T4LUP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A0A2EQG0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/36874:EL262_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A1T4LY19 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/36874:EL262_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A1T4JZ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/36874:EL262_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A0A2EW56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/36874:EL262_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A0A2ERX6 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/36874:EL262_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A0A2EKB1 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/36874:EL262_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A099WSP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/36874:EL262_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A1T4MU81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/36874:EL262_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A099WQR6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A099X001 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/36874:EL262_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQP9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/36874:EL262_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A099WZY3 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/36874:EL262_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A1T4JL43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/36874:EL262_RS00115 ^@ http://purl.uniprot.org/uniprot/A0A1T4MUP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A1T4KFJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/36874:EL262_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A1T4NAS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A099WTG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/36874:EL262_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A1T4JT60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A099WXC0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A1T4JMY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A1T4KI90 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/36874:EL262_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A1T4K683 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/36874:EL262_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A1T4L3V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A1T4LTI7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A1T4KAS2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/36874:EL262_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A099WUE4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A1T4MNJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A1T4M0F3 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/36874:EL262_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A1T4N357 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/36874:EL262_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A1T4NAJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/36874:EL262_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A1T4L3A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A1T4KNF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/36874:EL262_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A1T4KWW0 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/36874:EL262_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A099WZP2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/36874:EL262_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A1T4KQ63 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/36874:EL262_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A1T4M8N0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/36874:EL262_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A1T4KMF6 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/36874:EL262_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A1T4NDC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/36874:EL262_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A1T4MW93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.|||Membrane http://togogenome.org/gene/36874:EL262_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A1T4NFG6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/36874:EL262_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/36874:EL262_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A099WRD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/36874:EL262_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/36874:EL262_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A099WQ38 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/36874:EL262_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A1T4JMJ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/36874:EL262_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A099WQ04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/36874:EL262_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A1T4K4A9 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/36874:EL262_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A1T4JRC6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/36874:EL262_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A0A2EMX0 ^@ Caution|||Similarity ^@ Belongs to the SusD family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS09050 ^@ http://purl.uniprot.org/uniprot/A0A1T4JQH4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.|||Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A1T4KC47 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/36874:EL262_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A099WUU9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/36874:EL262_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A1T4NF02 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/36874:EL262_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A099WZ19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/36874:EL262_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A1T4JMG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/36874:EL262_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A099WTU1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A099WSD2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A1T4KSD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/36874:EL262_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A1T4K449 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/36874:EL262_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A1T4NQI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A1T4KYK6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/36874:EL262_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A099WZH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/36874:EL262_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A0A2EGS7 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/36874:EL262_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A1T4LPE1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/36874:EL262_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A1T4MEE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/36874:EL262_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A1T4JLU5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/36874:EL262_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A1T4JKU2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/36874:EL262_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A0A2EGZ5 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/36874:EL262_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A099WXN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A1T4MF15 ^@ Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/36874:EL262_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1T4K288 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A099WZL0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/36874:EL262_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A1T4LAM5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A1T4KN44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/36874:EL262_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A1T4KPA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/36874:EL262_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A099WVC3 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/36874:EL262_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A1T4LAA7 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS09460 ^@ http://purl.uniprot.org/uniprot/A0A1T4JTF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A1T4NJW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/36874:EL262_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A099WZR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/36874:EL262_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A0A2EMP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/36874:EL262_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A1T4M879 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/36874:EL262_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A099WZA7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/36874:EL262_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A099WVD6 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/36874:EL262_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A1T4MWV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A1T4JWH1 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/36874:EL262_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A1T4KRX8 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/36874:EL262_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A1T4K0Q2 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/36874:EL262_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A1T4LZD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/36874:EL262_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A099WSZ9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/36874:EL262_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A1T4JNR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/36874:EL262_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A1T4LA73 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/36874:EL262_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A099WX68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/36874:EL262_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A1T4JM95 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/36874:EL262_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A1T4LTQ2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/36874:EL262_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A1T4JY37 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/36874:EL262_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A1T4K630 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/36874:EL262_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A099WNI6 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/36874:EL262_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A1T4M9E4 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family.