http://togogenome.org/gene/420245:LBRM_19_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3N4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/420245:LBRM_34_3780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHC5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/420245:LBRM_31_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHX3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/420245:LBRM_05_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_35_6030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJI7 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/420245:LBRM_25_1910 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_19_1430 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_24_0110 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7I9 ^@ Function|||Subunit ^@ Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase VP55 that creates mRNA's poly(A) tail. In the presence of VP39, VP55 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.|||Methyltransferase activity: Monomer, poly(A) polymerase activity: Heterodimer composed of a catalytic component, VP55, and a processivity factor, VP39. Interacts with Rap94 and NPH-I; these interactions might help linking transcription to capping and polyadenylation. http://togogenome.org/gene/420245:LBRM_09_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_2550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/420245:LBRM_28_2700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB93 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/420245:LBRM_26_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_34_3830 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHQ6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/420245:LBRM_17_1580 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z334 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_1680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGS6 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_34_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGF1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/420245:LBRM_30_0820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/420245:LBRM_11_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z072 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/420245:LBRM_26_1960 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_21_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z680 ^@ Similarity|||Subunit ^@ Belongs to the helicase family. PIF1 subfamily.|||Monomer. http://togogenome.org/gene/420245:LBRM_17_0080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2L6 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_04_1170 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXL9 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/420245:LBRM_24_2160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z876 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/420245:LBRM_33_1900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFU1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_30_3690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDC2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_15_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/420245:LBRM_27_2550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA96 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/420245:LBRM_18_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_15_1380 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z240 ^@ Similarity ^@ Belongs to the NOP5/NOP56 family. http://togogenome.org/gene/420245:LBRM_14_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1H9 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/420245:LBRM_34_4450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI12 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/420245:LBRM_34_4560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_30_3000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Component of the ribosomal small subunit (SSU) processome.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.|||nucleolus http://togogenome.org/gene/420245:LBRM_31_2110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Component of the 60S subunit of the ribosome.|||Cytoplasm|||Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus|||Ribosomal protein L40 is part of the 60S ribosomal subunit. http://togogenome.org/gene/420245:LBRM_15_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z261 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/420245:LBRM_17_1500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3A5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDA1 family.|||Required for 60S pre-ribosomal subunits export to the cytoplasm.|||nucleolus http://togogenome.org/gene/420245:LBRM_26_2120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_4310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI03 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/420245:LBRM_32_0550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHU3 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family.|||Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. http://togogenome.org/gene/420245:LBRM_33_2420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGM1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_25_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z862 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/420245:LBRM_30_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0220 family.|||Membrane http://togogenome.org/gene/420245:LBRM_14_1020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_04_0350 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXB3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/420245:LBRM_06_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY32 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/420245:LBRM_32_1570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEL1 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/420245:LBRM_30_1610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCL0 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/420245:LBRM_35_4770 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJI3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/420245:LBRM_05_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXK6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Nucleus|||Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.|||The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). http://togogenome.org/gene/420245:LBRM_26_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z912 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/420245:LBRM_21_2000 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCU (TC 1.A.77) family.|||Membrane|||Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_35_3980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIY5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/420245:LBRM_08_0540 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYV0 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/420245:LBRM_35_5840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/420245:LBRM_05_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/420245:LBRM_25_1510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8U0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_21_1810 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6B0 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/420245:LBRM_29_1400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/420245:LBRM_05_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXP0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_23_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7K2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/420245:LBRM_30_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCH2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/420245:LBRM_31_2680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_10_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZT5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/420245:LBRM_33_3480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/420245:LBRM_31_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_4110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF78 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/420245:LBRM_25_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8A2 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/420245:LBRM_29_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/420245:LBRM_27_1590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9Z1 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/420245:LBRM_35_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Nucleus http://togogenome.org/gene/420245:LBRM_30_3120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD89 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_16_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2L9 ^@ Function|||Similarity ^@ Belongs to the calflagin family.|||May contribute to the rapid motility of the trypanosomes, playing a role either in flagellar structure or in calcium metabolism. Could alternate between a GDP-bound inactive form to a calcium/GTP-bound active form. http://togogenome.org/gene/420245:LBRM_26_1890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9D9 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/420245:LBRM_29_2900 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_34_4690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHR6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/420245:LBRM_28_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/420245:LBRM_18_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z340 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/420245:LBRM_35_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHY9 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/420245:LBRM_32_3970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM18 family.|||Membrane http://togogenome.org/gene/420245:LBRM_18_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3C8 ^@ Similarity ^@ Belongs to the WD repeat ARPC1 family. http://togogenome.org/gene/420245:LBRM_17_0180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2Q2 ^@ Similarity ^@ Belongs to the peptidase M20A family.|||Belongs to the peptidase M20B family. http://togogenome.org/gene/420245:LBRM_19_1800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z413 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/420245:LBRM_14_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. http://togogenome.org/gene/420245:LBRM_30_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ku80 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_23_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z794 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Mitochondrion matrix|||NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. http://togogenome.org/gene/420245:LBRM_02_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWT4 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/420245:LBRM_05_0350 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Trypanothione is the parasite analog of glutathione; this enzyme is the equivalent of glutathione reductase. http://togogenome.org/gene/420245:LBRM_23_0370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z704 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/420245:LBRM_15_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1N8 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/420245:LBRM_30_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCC1 ^@ Similarity ^@ Belongs to the MDM20/NAA25 family. http://togogenome.org/gene/420245:LBRM_15_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z207 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.|||Early endosome membrane|||Endosome membrane|||Membrane|||phagosome membrane http://togogenome.org/gene/420245:LBRM_30_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM NCBP2 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_31_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_18_0450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z386 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFZ6 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/420245:LBRM_24_1340 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z844 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_2280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Membrane http://togogenome.org/gene/420245:LBRM_27_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS18 family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_3520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light intermediate chain family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_18_0290 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z347 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/420245:LBRM_30_3180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMG-CoA reductase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/420245:LBRM_34_1570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR4 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/420245:LBRM_35_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIL1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/420245:LBRM_29_1130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBN0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_24_2390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8C4 ^@ Similarity ^@ Belongs to the UPF0610 family. http://togogenome.org/gene/420245:LBRM_30_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SDHAF2 family.|||Interacts with the flavoprotein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. http://togogenome.org/gene/420245:LBRM_26_0890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z952 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/420245:LBRM_24_1200 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z832 ^@ Similarity ^@ Belongs to the SURF6 family. http://togogenome.org/gene/420245:LBRM_33_0911 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G7 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/420245:LBRM_34_4670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI05 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_07_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYI4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/420245:LBRM_14_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z175 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_10_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZK5 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/420245:LBRM_35_5400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJJ1 ^@ Caution|||Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_28_3110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG8 family.|||Membrane http://togogenome.org/gene/420245:LBRM_24_2140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z812 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/420245:LBRM_34_2950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA12 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_29_2510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC35 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/420245:LBRM_34_2750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH17 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/420245:LBRM_22_1440 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6V5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Mitochondrion|||Monomer. http://togogenome.org/gene/420245:LBRM_23_1690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7D1 ^@ Similarity ^@ Belongs to the CFAP53 family. http://togogenome.org/gene/420245:LBRM_26_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z902 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/420245:LBRM_14_1540 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1L3 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/420245:LBRM_11_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0A9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/420245:LBRM_05_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXS3 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/420245:LBRM_15_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1Y1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Membrane|||Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. http://togogenome.org/gene/420245:LBRM_05_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY59 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/420245:LBRM_35_3210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ74 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/420245:LBRM_27_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9V5 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/420245:LBRM_34_1960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHC3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/420245:LBRM_31_3590 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE28 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/420245:LBRM_29_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBA4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_32_3240 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFC5 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/420245:LBRM_32_1760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEJ2 ^@ Similarity|||Subunit ^@ Belongs to the helicase family. PIF1 subfamily.|||Monomer. http://togogenome.org/gene/420245:LBRM_34_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGY0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_32_3720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF32 ^@ Similarity ^@ Belongs to the FAM161 family. http://togogenome.org/gene/420245:LBRM_30_3510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD63 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/420245:LBRM_28_1900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAW4 ^@ Similarity ^@ Belongs to the proteasome subunit S1 family. http://togogenome.org/gene/420245:LBRM_21_1580 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6A1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/420245:LBRM_32_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_31_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD72 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/420245:LBRM_18_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z348 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. http://togogenome.org/gene/420245:LBRM_21_0460 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5Z1 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/420245:LBRM_35_3230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ28 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/420245:LBRM_34_2300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH50 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/420245:LBRM_35_4000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJF6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/420245:LBRM_30_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCM4 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/420245:LBRM_21_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z661 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_32_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEM0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_16_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM5 / TYW2 family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/420245:LBRM_08_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYZ7 ^@ Similarity ^@ Belongs to the SEC3 family. http://togogenome.org/gene/420245:LBRM_29_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBM3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_27_1520 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9Z8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/420245:LBRM_21_1130 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6E5 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/420245:LBRM_24_2360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z836 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/420245:LBRM_35_0680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_33_2550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DeSI family.|||Belongs to the glycosyl hydrolase 85 family.|||cytosol http://togogenome.org/gene/420245:LBRM_23_1280 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z792 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM234 family.|||Membrane http://togogenome.org/gene/420245:LBRM_18_1430 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3H1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/420245:LBRM_21_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z690 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_05_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXQ8 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/420245:LBRM_35_3800 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/420245:LBRM_32_4060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF77 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_28_2400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 63 family.|||Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.|||Endoplasmic reticulum membrane http://togogenome.org/gene/420245:LBRM_14_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z4J0 ^@ Similarity ^@ Belongs to the SNF8 family. http://togogenome.org/gene/420245:LBRM_32_1460 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEG3 ^@ Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. http://togogenome.org/gene/420245:LBRM_33_0830 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6P9 ^@ Similarity ^@ Belongs to the ATPase gamma chain family. http://togogenome.org/gene/420245:LBRM_22_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6U0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Belongs to the NDUFAF7 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_28_0220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAC8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_33_3420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG86 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/420245:LBRM_35_4340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJF4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/420245:LBRM_10_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/420245:LBRM_35_3380 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ92 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/420245:LBRM_15_0401 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/420245:LBRM_08_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ01 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/420245:LBRM_17_1550 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3B6 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/420245:LBRM_07_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYR3 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/420245:LBRM_23_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z782 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_2170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGA1 ^@ Similarity ^@ Belongs to the CEP43 family. http://togogenome.org/gene/420245:LBRM_33_2610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC45 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_28_2870 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBJ2 ^@ Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family. http://togogenome.org/gene/420245:LBRM_16_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/420245:LBRM_34_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Membrane http://togogenome.org/gene/420245:LBRM_12_0910 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_12_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_01_0430 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWP4 ^@ Similarity ^@ Belongs to the dymeclin family. http://togogenome.org/gene/420245:LBRM_35_5130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ81 ^@ Similarity ^@ Belongs to the DNAAF1 family. http://togogenome.org/gene/420245:LBRM_27_0200 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_35_3620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIU3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/420245:LBRM_35_4110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit I family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_15_1570 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z219 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND1 (condensin subunit 1) family.|||Chromosome|||Nucleus http://togogenome.org/gene/420245:LBRM_19_1080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_2670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZES0 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_28_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAT1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/420245:LBRM_10_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZS6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M8 family.|||Binds 1 zinc ion per subunit.|||Has an integral role during the infection of macrophages in the mammalian host. http://togogenome.org/gene/420245:LBRM_21_2070 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G0 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/420245:LBRM_27_2400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAE7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/420245:LBRM_17_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z307 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_30_3340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/420245:LBRM_35_5180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_22_1170 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6V1 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/420245:LBRM_31_3310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE05 ^@ Function|||Similarity ^@ Belongs to the phytoene/squalene synthase family.|||Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. http://togogenome.org/gene/420245:LBRM_24_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7V8 ^@ Similarity ^@ Belongs to the TCTP family. http://togogenome.org/gene/420245:LBRM_18_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/420245:LBRM_23_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z701 ^@ Similarity ^@ Belongs to the HUS1 family. http://togogenome.org/gene/420245:LBRM_05_0130 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXT4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_14_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z4K4 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/420245:LBRM_31_2560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE24 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.|||Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/420245:LBRM_06_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYA3 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. http://togogenome.org/gene/420245:LBRM_25_1990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane|||Regulates also the sphingolipid metabolism. http://togogenome.org/gene/420245:LBRM_32_2450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEQ2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/420245:LBRM_23_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7G1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. RsmH family. http://togogenome.org/gene/420245:LBRM_28_2620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB25 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/420245:LBRM_35_1880 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIA6 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/420245:LBRM_22_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6R7 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/420245:LBRM_15_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z206 ^@ Similarity ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily. http://togogenome.org/gene/420245:LBRM_35_3500 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIT3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/420245:LBRM_15_0540 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1T2 ^@ Similarity ^@ Belongs to the protease inhibitor I11 (ecotin) family. http://togogenome.org/gene/420245:LBRM_27_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9N7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/420245:LBRM_21_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6H1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/420245:LBRM_18_1410 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3H9 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/420245:LBRM_30_3760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/420245:LBRM_19_0440 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/420245:LBRM_32_1270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z661 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_35_4220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ77 ^@ Similarity ^@ Belongs to the CDC73 family. http://togogenome.org/gene/420245:LBRM_14_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_01_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_26_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z983 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit beta family. http://togogenome.org/gene/420245:LBRM_08_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYR2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/420245:LBRM_35_3090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIM7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/420245:LBRM_34_2140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHE9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KMP-11 family.|||Monomer.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_29_2570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_1920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGT3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/420245:LBRM_33_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFK6 ^@ Similarity ^@ Belongs to the IWR1/SLC7A6OS family. http://togogenome.org/gene/420245:LBRM_21_0120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_31_3330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE17 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_35_4090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAP2/GCS1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/420245:LBRM_14_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1E4 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/420245:LBRM_34_2120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGY5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/420245:LBRM_10_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_26_1660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9D6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/420245:LBRM_32_3270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_21_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z674 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_35_2370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIF5 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/420245:LBRM_19_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z017 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_09_1540 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TET family. JBP1 subfamily.|||Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Also specifically binds to base J-containing DNA (J-DNA). Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis. Thymine dioxygenase activity and J-DNA-binding are independent functions.|||Monomer. Binds to DNA as a monomer.|||Nucleus http://togogenome.org/gene/420245:LBRM_04_0530 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXE3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_35_4140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIZ8 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/420245:LBRM_35_3320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ35 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/420245:LBRM_14_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_3230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAT1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/420245:LBRM_33_1510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGJ6 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_16_1590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/420245:LBRM_32_4080 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_3430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIS4 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/420245:LBRM_22_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6K0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG92 ^@ Similarity ^@ Belongs to the UQCRB/QCR7 family. http://togogenome.org/gene/420245:LBRM_02_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.|||Cytoplasm|||Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. http://togogenome.org/gene/420245:LBRM_14_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1P1 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/420245:LBRM_29_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBK6 ^@ Similarity ^@ Belongs to the NFX1 family. http://togogenome.org/gene/420245:LBRM_31_2970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDY0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_35_6050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/420245:LBRM_22_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6V3 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/420245:LBRM_07_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYJ0 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/420245:LBRM_21_1280 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/420245:LBRM_10_0970 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZT5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/420245:LBRM_05_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXN6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_04_1020 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.|||nucleolus http://togogenome.org/gene/420245:LBRM_03_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWZ0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/420245:LBRM_22_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6S6 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/420245:LBRM_24_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7K3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_35_5640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJE5 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/420245:LBRM_35_6410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJL4 ^@ Similarity ^@ Belongs to the CNOT10 family. http://togogenome.org/gene/420245:LBRM_32_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZED1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_24_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7M1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/420245:LBRM_35_1200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIB2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/420245:LBRM_31_2810 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDV9 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/420245:LBRM_17_0260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2Q8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_23_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z779 ^@ Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family. http://togogenome.org/gene/420245:LBRM_24_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7P4 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/420245:LBRM_22_0530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6W4 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/420245:LBRM_14_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_34_4230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/420245:LBRM_27_1800 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA62 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Cytoplasm|||In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. http://togogenome.org/gene/420245:LBRM_34_1340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal targeting signal receptor family.|||Cytoplasm|||Membrane http://togogenome.org/gene/420245:LBRM_16_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2A0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/420245:LBRM_01_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWI9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_35_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIH9 ^@ Similarity ^@ Belongs to the eukaryotic ATPase epsilon family. http://togogenome.org/gene/420245:LBRM_10_1120 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_34_3770 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHC5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/420245:LBRM_31_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD99 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_27_1690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/420245:LBRM_26_2500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9P1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_15_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z228 ^@ Similarity ^@ Belongs to the SPCS3 family. http://togogenome.org/gene/420245:LBRM_23_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6Y6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_13_1420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z197 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/420245:LBRM_09_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZD2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_35_6720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK52 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/420245:LBRM_28_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP52 family.|||Cytoplasm|||flagellum http://togogenome.org/gene/420245:LBRM_28_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAI9 ^@ Similarity ^@ Belongs to the VPS37 family. http://togogenome.org/gene/420245:LBRM_30_0370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGI0 ^@ Subcellular Location Annotation ^@ trans-Golgi network http://togogenome.org/gene/420245:LBRM_33_2210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFV1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/420245:LBRM_35_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIK4 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/420245:LBRM_32_2580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZER6 ^@ Similarity ^@ Belongs to the nucleoporin NSP1/NUP62 family. http://togogenome.org/gene/420245:LBRM_35_1750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. http://togogenome.org/gene/420245:LBRM_34_3040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_35_6760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_22_0370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6M0 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/420245:LBRM_33_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFE6 ^@ Similarity ^@ Belongs to the IFT57 family. http://togogenome.org/gene/420245:LBRM_15_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z202 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/420245:LBRM_34_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_30_1940 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCQ8 ^@ Similarity ^@ Belongs to the APC1 family. http://togogenome.org/gene/420245:LBRM_24_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7W4 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/420245:LBRM_30_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC81 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_01_0470 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWJ0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/420245:LBRM_31_1950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDP7 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_30_3380 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/420245:LBRM_24_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7Q1 ^@ Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Homodimer. http://togogenome.org/gene/420245:LBRM_29_0450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBG6 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/420245:LBRM_33_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGK9 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/420245:LBRM_27_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9V1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_28_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAS4 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/420245:LBRM_11_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0A0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/420245:LBRM_28_1250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAZ9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Vacuole membrane http://togogenome.org/gene/420245:LBRM_14_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1D6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_18_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_27_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA60 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_19_1860 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z4A3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_35_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIB2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/420245:LBRM_32_3670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF19 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_35_7200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_31_1550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDL9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_24_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7X0 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/420245:LBRM_35_4260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/420245:LBRM_11_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z054 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_0930 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6R1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/420245:LBRM_24_1970 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7Z9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_30_1170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_5610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_19_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG86 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/420245:LBRM_24_2330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z826 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_25_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/420245:LBRM_25_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8R5 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. http://togogenome.org/gene/420245:LBRM_22_1330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6U5 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_28_2600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB79 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family. http://togogenome.org/gene/420245:LBRM_21_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_24_2090 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8A0 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/420245:LBRM_26_1840 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9B8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/420245:LBRM_23_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7E6 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. http://togogenome.org/gene/420245:LBRM_28_2220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA13 subunit family.|||Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_11_0890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0J8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/420245:LBRM_33_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFK2 ^@ Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family.|||Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences. http://togogenome.org/gene/420245:LBRM_29_2480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC30 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by AMP.|||Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Glycosome|||Homotetramer. http://togogenome.org/gene/420245:LBRM_23_1720 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7D4 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6. http://togogenome.org/gene/420245:LBRM_05_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXN9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/420245:LBRM_30_3020 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_10_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_3400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ44 ^@ Function ^@ Could act as a receptor for an unknown ligand. http://togogenome.org/gene/420245:LBRM_34_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGQ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_29_2140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC70 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/420245:LBRM_22_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6U1 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/420245:LBRM_15_1560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z214 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_25_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8L7 ^@ Similarity ^@ Belongs to the SLBP family. http://togogenome.org/gene/420245:LBRM_04_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXJ3 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/420245:LBRM_23_1760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7M7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Converts protoheme IX and farnesyl diphosphate to heme O.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/420245:LBRM_26_1830 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/420245:LBRM_04_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXJ8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_13_1540 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1D1 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/420245:LBRM_24_2350 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z896 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_29_0130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBC7 ^@ Similarity ^@ Belongs to the proteasome subunit S2 family. http://togogenome.org/gene/420245:LBRM_29_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBE6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/420245:LBRM_35_3540 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIU2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/420245:LBRM_13_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z169 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/420245:LBRM_35_1480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI59 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/420245:LBRM_16_0860 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2C8 ^@ Similarity ^@ Belongs to the peptidase M67A family. CSN5 subfamily. http://togogenome.org/gene/420245:LBRM_14_1280 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z4I8 ^@ Similarity ^@ Belongs to the PTEN phosphatase protein family. http://togogenome.org/gene/420245:LBRM_34_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYZ8 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/420245:LBRM_23_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7D3 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/420245:LBRM_35_7120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK74 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/420245:LBRM_18_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F3 ^@ Function|||Similarity ^@ Belongs to the peptidase C13 family.|||Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. http://togogenome.org/gene/420245:LBRM_13_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0R5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/420245:LBRM_35_6690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJQ6 ^@ Similarity ^@ Belongs to the TMA16 family. http://togogenome.org/gene/420245:LBRM_35_5430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJC3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/420245:LBRM_21_1270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z667 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_07_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYG0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_35_1570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI82 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/420245:LBRM_34_2850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHN4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family.|||Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues. http://togogenome.org/gene/420245:LBRM_09_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ51 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_25_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/420245:LBRM_33_2590 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG07 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/420245:LBRM_33_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFE9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/420245:LBRM_30_2440 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCY0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_25_0790 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8D3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_13_0770 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z180 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.|||Cytoplasm|||Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.|||cytoskeleton|||spindle|||spindle pole http://togogenome.org/gene/420245:LBRM_35_5510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJD3 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/420245:LBRM_01_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/420245:LBRM_02_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWS8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_23_1560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7B8 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_26_2410 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/420245:LBRM_22_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6P8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/420245:LBRM_33_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/420245:LBRM_15_1510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z255 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS1/PSF1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_18_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_04_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXF0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/420245:LBRM_07_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_28_2950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB69 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/420245:LBRM_34_2441 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHJ8 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/420245:LBRM_34_2000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH21 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_28_2570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBG8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_35_2980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIU0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_21_1740 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6D7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/420245:LBRM_08_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-X family.|||DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|||Nucleus http://togogenome.org/gene/420245:LBRM_24_1850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7Y2 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/420245:LBRM_07_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAPT1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_3230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum http://togogenome.org/gene/420245:LBRM_32_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZED7 ^@ Similarity ^@ Belongs to the VPS29 family. http://togogenome.org/gene/420245:LBRM_03_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX05 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/420245:LBRM_34_2390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGY4 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/420245:LBRM_24_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7J1 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/420245:LBRM_31_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBX2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. http://togogenome.org/gene/420245:LBRM_09_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZF1 ^@ Function|||Similarity ^@ Belongs to the calmodulin family.|||May be involved in calcium-mediated signal transduction. http://togogenome.org/gene/420245:LBRM_04_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXE6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_35_3450 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIT2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/420245:LBRM_24_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7W0 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/420245:LBRM_32_2780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF37 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/420245:LBRM_35_2400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_07_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_31_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBW3 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/420245:LBRM_29_2620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND3 (condensin subunit 3) family.|||Chromosome http://togogenome.org/gene/420245:LBRM_17_1210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z388 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_2240 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIX6 ^@ Function|||Similarity ^@ Belongs to the chaperonin (HSP60) family.|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_26_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8V8 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/420245:LBRM_25_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8E6 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/420245:LBRM_16_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z289 ^@ Similarity ^@ Belongs to the ELP3 family. http://togogenome.org/gene/420245:LBRM_32_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_2960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/420245:LBRM_35_7320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/420245:LBRM_31_1760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_28_0460 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAS7 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/420245:LBRM_22_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6T4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/420245:LBRM_30_3420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD51 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/420245:LBRM_22_1040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6S8 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/420245:LBRM_23_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z775 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/420245:LBRM_34_1760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_1480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCM0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/420245:LBRM_34_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH08 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/420245:LBRM_07_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYJ0 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/420245:LBRM_28_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAX2 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/420245:LBRM_07_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYF0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_10_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZL4 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/420245:LBRM_29_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBS2 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/420245:LBRM_05_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z875 ^@ Similarity ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily. http://togogenome.org/gene/420245:LBRM_28_2670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBH8 ^@ Similarity ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. http://togogenome.org/gene/420245:LBRM_28_2250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAY8 ^@ Similarity ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family. http://togogenome.org/gene/420245:LBRM_24_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/420245:LBRM_25_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8I0 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/420245:LBRM_35_4070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIZ0 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_30_2420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCV3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_27_1680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_32_1200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEE2 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/420245:LBRM_25_1270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8W0 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/420245:LBRM_26_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z929 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_35_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/420245:LBRM_31_3620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_30_3100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD11 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic AdoMetDC family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/420245:LBRM_28_2050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAW6 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/420245:LBRM_35_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIL1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/420245:LBRM_01_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWJ6 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/420245:LBRM_10_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_07_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYL1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_28_2060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB31 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_09_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZD6 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/420245:LBRM_23_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z790 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/420245:LBRM_29_0910 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBJ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/420245:LBRM_27_2050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/420245:LBRM_16_0930 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2B2 ^@ Function|||Similarity ^@ Belongs to the calflagin family.|||May contribute to the rapid motility of the trypanosomes, playing a role either in flagellar structure or in calcium metabolism. Could alternate between a GDP-bound inactive form to a calcium/GTP-bound active form. http://togogenome.org/gene/420245:LBRM_31_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Membrane http://togogenome.org/gene/420245:LBRM_10_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZI7 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/420245:LBRM_35_3280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIQ3 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_35_2390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/420245:LBRM_15_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z280 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.|||E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress. http://togogenome.org/gene/420245:LBRM_29_2840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_3110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHZ0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_02_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Membrane http://togogenome.org/gene/420245:LBRM_15_0550 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1V6 ^@ Similarity ^@ Belongs to the protease inhibitor I11 (ecotin) family. http://togogenome.org/gene/420245:LBRM_32_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE43 ^@ Similarity ^@ Belongs to the WD repeat SEC13 family. http://togogenome.org/gene/420245:LBRM_18_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z365 ^@ Similarity ^@ Belongs to the tubulin--tyrosine ligase family. http://togogenome.org/gene/420245:LBRM_35_7150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZKA0 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/420245:LBRM_25_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8U3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/420245:LBRM_13_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0N8 ^@ Caution|||Function|||Similarity ^@ Belongs to the RNase HII family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_29_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBL6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/420245:LBRM_18_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z397 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/420245:LBRM_05_1090 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_06_0350 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY19 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/420245:LBRM_22_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the battenin family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFF8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/420245:LBRM_30_0830 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCE5 ^@ Similarity ^@ Belongs to the GrpE family. http://togogenome.org/gene/420245:LBRM_18_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3A1 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/420245:LBRM_04_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXD9 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/420245:LBRM_30_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_3220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/420245:LBRM_04_0930 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXE0 ^@ Similarity ^@ Belongs to the TRAPPC13 family. http://togogenome.org/gene/420245:LBRM_21_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z631 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/420245:LBRM_05_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/420245:LBRM_08_0330 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYR9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/420245:LBRM_24_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z860 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/420245:LBRM_26_0110 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8U8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_23_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z788 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_13_1480 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z170 ^@ Function|||Similarity ^@ Belongs to the squalene monooxygenase family.|||Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. http://togogenome.org/gene/420245:LBRM_25_1710 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/420245:LBRM_09_1400 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZE6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_27_1370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_35_2580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIP8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/420245:LBRM_28_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.|||Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_16_1090 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2E1 ^@ Function|||Similarity ^@ Belongs to the UFM1 family.|||Ubiquitin-like modifier. http://togogenome.org/gene/420245:LBRM_30_2790 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCY4 ^@ Function|||Similarity ^@ Belongs to the chaperonin (HSP60) family.|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_01_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_30_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCK4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS30 family. http://togogenome.org/gene/420245:LBRM_23_1360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7A3 ^@ Similarity ^@ Belongs to the RICTOR family. http://togogenome.org/gene/420245:LBRM_13_1520 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_33_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFP0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_25_0890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8K7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/420245:LBRM_14_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_29_2720 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0Q3 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/420245:LBRM_27_2480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA85 ^@ Similarity ^@ Belongs to the SPT5 family. http://togogenome.org/gene/420245:LBRM_21_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6A5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/420245:LBRM_28_1960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAV9 ^@ Similarity ^@ Belongs to the AAA ATPase family. PCH2 subfamily. http://togogenome.org/gene/420245:LBRM_25_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z872 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_3430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD69 ^@ Similarity ^@ Belongs to the XPO2/CSE1 family. http://togogenome.org/gene/420245:LBRM_21_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5Y3 ^@ Similarity ^@ Belongs to the VPS51 family. http://togogenome.org/gene/420245:LBRM_10_1090 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZT5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/420245:LBRM_35_4740 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ47 ^@ Similarity ^@ Belongs to the CFAP298 family. http://togogenome.org/gene/420245:LBRM_18_0130 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z345 ^@ Similarity ^@ Belongs to the TMCO4 family. http://togogenome.org/gene/420245:LBRM_11_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer. http://togogenome.org/gene/420245:LBRM_09_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZF1 ^@ Function|||Similarity ^@ Belongs to the calmodulin family.|||May be involved in calcium-mediated signal transduction. http://togogenome.org/gene/420245:LBRM_27_2560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAF0 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/420245:LBRM_33_2140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.|||Involved in the biogenesis of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/420245:LBRM_07_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYJ8 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/420245:LBRM_28_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB91 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_19_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3S5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/420245:LBRM_25_0240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8K0 ^@ Similarity ^@ Belongs to the CWC26 family. http://togogenome.org/gene/420245:LBRM_24_2370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8B8 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_34_3140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHQ9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/420245:LBRM_35_3710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIV4 ^@ Similarity ^@ Belongs to the SMAP family. http://togogenome.org/gene/420245:LBRM_22_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6W0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_08_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYZ0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_32_2050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_4660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJL0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/420245:LBRM_34_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGM7 ^@ Similarity ^@ Belongs to the peptidase C64 family. http://togogenome.org/gene/420245:LBRM_24_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7S0 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/420245:LBRM_34_3250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/420245:LBRM_17_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2S2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_14_1360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1J7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/420245:LBRM_27_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9U3 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/420245:LBRM_29_1410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBQ3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/420245:LBRM_34_2840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH27 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/420245:LBRM_34_4010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHW6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/420245:LBRM_02_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_28_2310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBE4 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_34_4710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHK0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/420245:LBRM_25_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8M4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/420245:LBRM_35_2250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIE8 ^@ Function|||Similarity ^@ Belongs to the chaperonin (HSP60) family.|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_07_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYK4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/420245:LBRM_30_1980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCS4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_04_0440 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXI9 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/420245:LBRM_09_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZE5 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/420245:LBRM_33_2180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFX4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/420245:LBRM_10_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZU0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_3600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH87 ^@ Similarity ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. http://togogenome.org/gene/420245:LBRM_35_4010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIY6 ^@ Similarity|||Subunit ^@ Belongs to the NAC-beta family.|||Part of the nascent polypeptide-associated complex (NAC). http://togogenome.org/gene/420245:LBRM_31_1980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDQ1 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/420245:LBRM_35_3140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIN6 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/420245:LBRM_31_2130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Component of the 60S subunit of the ribosome.|||Cytoplasm|||Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus|||Ribosomal protein L40 is part of the 60S ribosomal subunit. http://togogenome.org/gene/420245:LBRM_35_3650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJA1 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/420245:LBRM_16_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2I4 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/420245:LBRM_22_1540 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_07_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYD1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.|||Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.|||In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.|||Nucleus http://togogenome.org/gene/420245:LBRM_35_7260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK18 ^@ Similarity ^@ Belongs to the non-repetitive/WGA-negative nucleoporin family. http://togogenome.org/gene/420245:LBRM_32_1900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COPE family.|||Cytoplasm|||Membrane|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/420245:LBRM_19_1120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS53 family.|||Endosome membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/420245:LBRM_29_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBJ3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_28_3090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI4 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/420245:LBRM_23_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z761 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/420245:LBRM_34_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGP7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_35_4600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_13_0470 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0W4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_30_1950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCU1 ^@ Subcellular Location Annotation ^@ cilium http://togogenome.org/gene/420245:LBRM_34_2970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHM6 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/420245:LBRM_33_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_1950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFU6 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/420245:LBRM_32_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEF7 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/420245:LBRM_12_0080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0F0 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/420245:LBRM_34_5180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/420245:LBRM_22_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXF0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/420245:LBRM_22_0540 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6M8 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/420245:LBRM_05_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_14_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1A8 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/420245:LBRM_31_1890 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS3/PSF3 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_2090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFT4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/420245:LBRM_29_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBX3 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/420245:LBRM_29_1600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_07_1110 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYQ8 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. http://togogenome.org/gene/420245:LBRM_05_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_09_1080 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZG4 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/420245:LBRM_19_1290 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3V4 ^@ Similarity ^@ Belongs to the WD repeat LST8 family. http://togogenome.org/gene/420245:LBRM_34_0440 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGC7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/420245:LBRM_32_4070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_1000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEB9 ^@ Function|||Similarity ^@ Belongs to the AB hydrolase superfamily.|||Demethylates proteins that have been reversibly carboxymethylated. http://togogenome.org/gene/420245:LBRM_29_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBM6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/420245:LBRM_32_4160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFM6 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/420245:LBRM_28_2340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB56 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/420245:LBRM_19_1170 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z435 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/420245:LBRM_26_1500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z990 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG7 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/420245:LBRM_17_0090 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2W9 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/420245:LBRM_07_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.|||Belongs to the adaptor complexes large subunit family.|||coated pit http://togogenome.org/gene/420245:LBRM_25_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8A2 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/420245:LBRM_18_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z368 ^@ Similarity ^@ Belongs to the FAM221 family. http://togogenome.org/gene/420245:LBRM_19_1610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_1970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGM family.|||Endoplasmic reticulum membrane|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.|||Membrane http://togogenome.org/gene/420245:LBRM_35_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI57 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/420245:LBRM_15_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z292 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/420245:LBRM_15_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1N4 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/420245:LBRM_30_3160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MNS1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_30_2890 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD16 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_35_4900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/420245:LBRM_28_2510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_10_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z007 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/420245:LBRM_35_5000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_2880 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF46 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/420245:LBRM_33_2260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGA6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_13_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0Y7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/420245:LBRM_11_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0A7 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/420245:LBRM_33_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/420245:LBRM_14_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1K2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/420245:LBRM_35_7160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK13 ^@ Similarity ^@ Belongs to the UFL1 family. http://togogenome.org/gene/420245:LBRM_10_1080 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZT5 ^@ Similarity ^@ Belongs to the histone H3 family. http://togogenome.org/gene/420245:LBRM_28_2080 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAX0 ^@ Similarity ^@ Belongs to the BCP1 family. http://togogenome.org/gene/420245:LBRM_30_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFB2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_25_1400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT2/3/5 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_32_3290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_19_1850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z405 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_32_4050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFL8 ^@ Similarity ^@ Belongs to the SHQ1 family. http://togogenome.org/gene/420245:LBRM_13_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0U7 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/420245:LBRM_30_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_2420 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP53 family.|||nucleolus|||nucleoplasm http://togogenome.org/gene/420245:LBRM_28_1990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||Nucleus http://togogenome.org/gene/420245:LBRM_16_1210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC08 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/420245:LBRM_05_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXS9 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family.|||Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/420245:LBRM_05_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Membrane http://togogenome.org/gene/420245:LBRM_27_1870 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA39 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/420245:LBRM_34_1820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGV7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/420245:LBRM_34_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGM6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/420245:LBRM_14_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z4L2 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/420245:LBRM_14_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1G3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/420245:LBRM_27_2180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAC5 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/420245:LBRM_14_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1I8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/420245:LBRM_32_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE93 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily. http://togogenome.org/gene/420245:LBRM_34_4640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAPC3/SRD2 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_4170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHM3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_25_1680 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KIF-binding protein family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_34_4850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHM0 ^@ Similarity ^@ Belongs to the RecA family. DMC1 subfamily. http://togogenome.org/gene/420245:LBRM_18_0910 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3C2 ^@ Similarity ^@ Belongs to the GCN1 family. http://togogenome.org/gene/420245:LBRM_30_2300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCU4 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/420245:LBRM_30_2200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the REI1 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_34_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/420245:LBRM_32_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE81 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/420245:LBRM_08_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYY5 ^@ Similarity ^@ Belongs to the dpy-30 family. http://togogenome.org/gene/420245:LBRM_28_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAW2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_33_2510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG18 ^@ Similarity ^@ Belongs to the CFAP91 family. http://togogenome.org/gene/420245:LBRM_02_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_2990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHH4 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/420245:LBRM_07_0090 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYD6 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/420245:LBRM_08_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYT3 ^@ Similarity ^@ Belongs to the neutral sphingomyelinase family. http://togogenome.org/gene/420245:LBRM_32_4030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFM0 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/420245:LBRM_08_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYR7 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/420245:LBRM_27_1920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA38 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/420245:LBRM_14_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1H3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_35_1270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI50 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/420245:LBRM_07_1120 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYP6 ^@ Similarity ^@ Belongs to the dpy-30 family. http://togogenome.org/gene/420245:LBRM_35_6810 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJS3 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/420245:LBRM_10_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZP6 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/420245:LBRM_01_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWM9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_15_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z208 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. http://togogenome.org/gene/420245:LBRM_32_2030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEP2 ^@ Function|||Similarity ^@ Belongs to the chaperonin (HSP60) family.|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_35_5520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJD2 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/420245:LBRM_26_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. LDAH family.|||Lipid droplet http://togogenome.org/gene/420245:LBRM_23_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z735 ^@ Similarity ^@ Belongs to the DIM1 family. http://togogenome.org/gene/420245:LBRM_14_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1H4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Choline transporter.|||Membrane http://togogenome.org/gene/420245:LBRM_34_3760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHA6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/420245:LBRM_27_2160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.|||Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.|||nucleolus http://togogenome.org/gene/420245:LBRM_24_1560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7Z4 ^@ Similarity ^@ Belongs to the TRAPP small subunits family. BET3 subfamily. http://togogenome.org/gene/420245:LBRM_27_0220 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9R8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCC1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_19_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z012 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/420245:LBRM_28_1950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB23 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/420245:LBRM_35_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHV3 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/420245:LBRM_33_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/420245:LBRM_24_2420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z870 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/420245:LBRM_27_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9S8 ^@ Similarity ^@ Belongs to the CAND family. http://togogenome.org/gene/420245:LBRM_34_2150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHE9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KMP-11 family.|||Monomer.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_34_3970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_22_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6T2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/420245:LBRM_15_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_35_5650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJV8 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/420245:LBRM_18_1210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/420245:LBRM_27_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9W2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/420245:LBRM_14_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1J3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/420245:LBRM_33_3100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG56 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_33_1620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/420245:LBRM_32_1170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZES3 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/420245:LBRM_26_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z952 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/420245:LBRM_01_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_15_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1R6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_23_1860 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXR6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_02_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWV7 ^@ Similarity ^@ Belongs to the ARPC4 family. http://togogenome.org/gene/420245:LBRM_34_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAP2/GCS1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/420245:LBRM_13_1430 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z163 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_13_1000 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z109 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/420245:LBRM_27_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA00 ^@ Similarity ^@ Belongs to the WD repeat SMU1 family. http://togogenome.org/gene/420245:LBRM_32_3330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEZ6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_12_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0D8 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/420245:LBRM_27_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGJ3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_04_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXD1 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/420245:LBRM_32_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEZ3 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/420245:LBRM_35_2070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIV7 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/420245:LBRM_04_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYK2 ^@ Cofactor|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/420245:LBRM_03_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWY1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/420245:LBRM_32_3550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF14 ^@ Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. http://togogenome.org/gene/420245:LBRM_28_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_1630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHC8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_34_3740 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHA6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/420245:LBRM_26_2160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9F8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_09_0970 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZF1 ^@ Function|||Similarity ^@ Belongs to the calmodulin family.|||May be involved in calcium-mediated signal transduction. http://togogenome.org/gene/420245:LBRM_28_2480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/420245:LBRM_28_1030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD70 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/420245:LBRM_27_2210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA52 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/420245:LBRM_04_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXK9 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. http://togogenome.org/gene/420245:LBRM_23_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z791 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_21_1920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6E1 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/420245:LBRM_09_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ94 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. Torsin subfamily. http://togogenome.org/gene/420245:LBRM_31_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_04_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL29 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_28_2120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_30_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCC7 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_32_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZET2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_27_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH75 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/420245:LBRM_26_1710 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9J7 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/420245:LBRM_28_1460 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_28_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAU5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/420245:LBRM_35_3110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_12_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0K0 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/420245:LBRM_26_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z948 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/420245:LBRM_26_2140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9S2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/420245:LBRM_30_1920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDC3 ^@ Similarity ^@ Belongs to the ZNF277 family. http://togogenome.org/gene/420245:LBRM_23_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z783 ^@ Function|||Similarity ^@ Belongs to the BMT2 family.|||Probable S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/420245:LBRM_30_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCJ0 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/420245:LBRM_19_1750 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z496 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/420245:LBRM_16_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_19_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3V3 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/420245:LBRM_08_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/420245:LBRM_25_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8F1 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/420245:LBRM_35_6680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK29 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/420245:LBRM_14_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_3960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_07_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYK6 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/420245:LBRM_34_5200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AMY1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_24_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_28_2960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/420245:LBRM_28_2661 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBF2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/420245:LBRM_03_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX55 ^@ Similarity ^@ Belongs to the uroporphyrinogen-III synthase family. http://togogenome.org/gene/420245:LBRM_18_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z362 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_30_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_30_3550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDS9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/420245:LBRM_03_0260 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX11 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/420245:LBRM_30_2880 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCZ8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/420245:LBRM_18_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3C0 ^@ Similarity ^@ Belongs to the WD repeat PWP2 family. http://togogenome.org/gene/420245:LBRM_22_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.|||Nucleus http://togogenome.org/gene/420245:LBRM_31_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDB0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_35_5310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJQ7 ^@ Similarity ^@ Belongs to the NOB1 family. http://togogenome.org/gene/420245:LBRM_25_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_35_1540 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIE0 ^@ Similarity ^@ Belongs to the CFAP36 family. http://togogenome.org/gene/420245:LBRM_16_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2C9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/420245:LBRM_19_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3U9 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/420245:LBRM_18_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3E9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_30_2950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD00 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/420245:LBRM_18_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3L2 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 3 family. http://togogenome.org/gene/420245:LBRM_28_0550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAU3 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/420245:LBRM_16_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z268 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/420245:LBRM_35_3300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ58 ^@ Similarity ^@ Belongs to the LipB family. http://togogenome.org/gene/420245:LBRM_35_2890 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ41 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_34_4870 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI52 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/420245:LBRM_02_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_26_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z931 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/420245:LBRM_30_3620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD70 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/420245:LBRM_04_1030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_13_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z137 ^@ Similarity ^@ Belongs to the TCP10 family. http://togogenome.org/gene/420245:LBRM_33_1290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFL1 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/420245:LBRM_35_2040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIC2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_26_0330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9A2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/420245:LBRM_34_1730 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_35_2520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS4 family.|||Membrane|||centrosome|||cilium membrane http://togogenome.org/gene/420245:LBRM_05_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_15_1470 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z209 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/420245:LBRM_34_4130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_29_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBC0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/420245:LBRM_19_1660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z416 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/420245:LBRM_18_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F0 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/420245:LBRM_09_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0602 family.|||centrosome http://togogenome.org/gene/420245:LBRM_05_0180 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXL7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/420245:LBRM_19_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_28_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC1 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Nucleus|||ORC is composed of six subunits. http://togogenome.org/gene/420245:LBRM_09_1120 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZG7 ^@ Similarity ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. http://togogenome.org/gene/420245:LBRM_33_2630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 3-oxoacid CoA-transferase family.|||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_05_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/420245:LBRM_31_2010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_22_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6L9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_28_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAP6 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_08_0090 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYR6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Adaptor protein complex 3 (AP-3) is a heterotetramer.|||Belongs to the adaptor complexes large subunit family.|||Golgi apparatus http://togogenome.org/gene/420245:LBRM_35_1900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGC family.|||Membrane http://togogenome.org/gene/420245:LBRM_13_0220 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCC2/Nipped-B family.|||Nucleus http://togogenome.org/gene/420245:LBRM_24_1460 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z810 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/420245:LBRM_27_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9W8 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/420245:LBRM_03_0370 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_2130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZID9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/420245:LBRM_22_1420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z745 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/420245:LBRM_01_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWH5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/420245:LBRM_26_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z938 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/420245:LBRM_34_4410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_14_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_24_2150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z876 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/420245:LBRM_22_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6W2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/420245:LBRM_34_3360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHS7 ^@ Similarity ^@ Belongs to the XPC family. http://togogenome.org/gene/420245:LBRM_28_2610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RFT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in N-linked oligosaccharide assembly.|||Membrane http://togogenome.org/gene/420245:LBRM_18_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z387 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/420245:LBRM_32_3600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFF9 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/420245:LBRM_06_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LZTFL1 family.|||Cytoplasm|||Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.|||Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking. http://togogenome.org/gene/420245:LBRM_11_0180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z033 ^@ Similarity ^@ In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family. http://togogenome.org/gene/420245:LBRM_35_6180 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJJ9 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/420245:LBRM_33_2820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR1 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/420245:LBRM_19_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP11 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/420245:LBRM_11_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z037 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/420245:LBRM_21_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5X1 ^@ Similarity ^@ Belongs to the actin family. ARP6 subfamily. http://togogenome.org/gene/420245:LBRM_19_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3S9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_4880 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJP4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. http://togogenome.org/gene/420245:LBRM_22_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6P5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_33_3470 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_3310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHE6 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/420245:LBRM_09_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ4 family.|||Component of a multi-subunit COQ enzyme complex.|||Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_19_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z426 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP72 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_27_1850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_28_2270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB44 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/420245:LBRM_04_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXG8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_34_2340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_29_2360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC13 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_01_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_18_0870 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/420245:LBRM_16_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z234 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/420245:LBRM_32_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE99 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/420245:LBRM_30_2530 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCW6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_35_4430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_25_1030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8J0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SLX1 family.|||Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.|||Forms a heterodimer with a member of the SLX4 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/420245:LBRM_12_0680 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS5 family.|||Membrane|||centriolar satellite|||cilium membrane http://togogenome.org/gene/420245:LBRM_27_2630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HOP2 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_35_6830 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK65 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/420245:LBRM_33_2060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/420245:LBRM_32_4140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/420245:LBRM_33_2840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG54 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/420245:LBRM_06_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYB0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/420245:LBRM_26_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z918 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/420245:LBRM_24_2290 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8B3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/420245:LBRM_35_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHZ1 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/420245:LBRM_34_2040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHG8 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/420245:LBRM_29_2270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC15 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/420245:LBRM_04_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXC4 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/420245:LBRM_35_2150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZID5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/420245:LBRM_08_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYY0 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/420245:LBRM_32_3090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEW0 ^@ Subcellular Location Annotation ^@ Dynein axonemal particle|||neuron projection http://togogenome.org/gene/420245:LBRM_30_0220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCA0 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_06_0830 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY75 ^@ Function|||Similarity ^@ Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.|||In the C-terminal section; belongs to the thymidylate synthase family.|||In the N-terminal section; belongs to the dihydrofolate reductase family. http://togogenome.org/gene/420245:LBRM_13_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z177 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/420245:LBRM_05_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I 51 kDa subunit family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_34_4980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_35_5860 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJY6 ^@ Similarity ^@ Belongs to the CAP family. http://togogenome.org/gene/420245:LBRM_19_0460 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3K8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_35_3690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIV5 ^@ Similarity ^@ Belongs to the NipSnap family. http://togogenome.org/gene/420245:LBRM_34_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GPC1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_17_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z333 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/420245:LBRM_34_3560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHA0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/420245:LBRM_05_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_29_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBR9 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/420245:LBRM_28_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCI5 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/420245:LBRM_15_1040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1Y7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/420245:LBRM_10_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z048 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP16 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_35_2870 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIK7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/420245:LBRM_31_2920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDY1 ^@ Similarity ^@ Belongs to the UQCRH/QCR6 family. http://togogenome.org/gene/420245:LBRM_24_2060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z804 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/420245:LBRM_34_3920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_4810 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. http://togogenome.org/gene/420245:LBRM_33_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/420245:LBRM_31_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||nucleolus http://togogenome.org/gene/420245:LBRM_06_0620 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY54 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/420245:LBRM_11_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0H3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS21 family. http://togogenome.org/gene/420245:LBRM_24_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7V4 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/420245:LBRM_34_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_15_0402 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/420245:LBRM_28_2770 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/420245:LBRM_25_1130 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8F0 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. http://togogenome.org/gene/420245:LBRM_25_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8C7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/420245:LBRM_33_3330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosyl-DNA phosphodiesterase family.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_1960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||Nucleus http://togogenome.org/gene/420245:LBRM_27_2720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/420245:LBRM_06_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY18 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/420245:LBRM_34_5230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHX4 ^@ Similarity ^@ Belongs to the LSM12 family. http://togogenome.org/gene/420245:LBRM_11_0430 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z063 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_24_2120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z841 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/420245:LBRM_14_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_2720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin interacting component (NIC) family.|||nuclear pore complex http://togogenome.org/gene/420245:LBRM_34_0810 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGI6 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/420245:LBRM_28_2990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB76 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_34_4750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_2160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHE9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KMP-11 family.|||Monomer.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_28_1660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_04_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pescadillo family.|||Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.|||nucleolus|||nucleoplasm http://togogenome.org/gene/420245:LBRM_35_5900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJP3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_35_1380 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI54 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/420245:LBRM_35_3290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIR1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/420245:LBRM_06_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY41 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/420245:LBRM_27_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG9 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.|||Preautophagosomal structure membrane http://togogenome.org/gene/420245:LBRM_27_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9N4 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion|||Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/420245:LBRM_18_1640 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3J3 ^@ Similarity ^@ Belongs to the NOC2 family. http://togogenome.org/gene/420245:LBRM_32_3610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF11 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/420245:LBRM_35_1920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIH8 ^@ Similarity ^@ Belongs to the COG3 family. http://togogenome.org/gene/420245:LBRM_32_3210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF18 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/420245:LBRM_19_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3N9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/420245:LBRM_03_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/420245:LBRM_26_2620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_35_4690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJH3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/420245:LBRM_18_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z380 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/420245:LBRM_28_2710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB34 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/420245:LBRM_25_0080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z882 ^@ Similarity ^@ Belongs to the polyadenylate-binding protein type-1 family. http://togogenome.org/gene/420245:LBRM_32_3560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF06 ^@ Function|||Similarity ^@ Belongs to the TCP-1 chaperonin family.|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_21_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5Y1 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/420245:LBRM_23_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6X4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/420245:LBRM_34_1610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.|||nucleolus http://togogenome.org/gene/420245:LBRM_13_0970 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z104 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/420245:LBRM_34_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGC5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/420245:LBRM_22_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6P3 ^@ Similarity ^@ Belongs to the PRP18 family. http://togogenome.org/gene/420245:LBRM_26_1630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9J4 ^@ Function|||Similarity ^@ Belongs to the proline oxidase family.|||Converts proline to delta-1-pyrroline-5-carboxylate. http://togogenome.org/gene/420245:LBRM_28_2890 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX15/CtaA family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_2920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the POC5 family.|||Essential for the assembly of the distal half of centrioles, required for centriole elongation.|||centriole http://togogenome.org/gene/420245:LBRM_33_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFM5 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/420245:LBRM_10_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZH1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/420245:LBRM_18_1330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3H0 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/420245:LBRM_34_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_3050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH51 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/420245:LBRM_26_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM10 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_18_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z373 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_28_2630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/420245:LBRM_19_1690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z400 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/420245:LBRM_35_4230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJE3 ^@ Similarity ^@ Belongs to the peptidase T1B family. HslV subfamily. http://togogenome.org/gene/420245:LBRM_07_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYD3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/420245:LBRM_23_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_3280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD74 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_28_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAP7 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_23_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z733 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/420245:LBRM_08_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYQ5 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/420245:LBRM_29_2800 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC60 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/420245:LBRM_29_0730 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_35_6710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJR4 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/420245:LBRM_02_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_16_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_4220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Belongs to the NAF1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/420245:LBRM_27_1090 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9W4 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/420245:LBRM_07_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYH0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/420245:LBRM_27_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA23 ^@ Similarity ^@ Belongs to the flagellar radial spoke RSP3 family. http://togogenome.org/gene/420245:LBRM_30_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD05 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_10_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZQ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/420245:LBRM_04_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXH2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/420245:LBRM_11_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0I3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_15_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1X5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-16 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Peroxisome membrane http://togogenome.org/gene/420245:LBRM_13_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z148 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/420245:LBRM_24_1210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_06_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXZ8 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/420245:LBRM_28_1910 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAW5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/420245:LBRM_29_1270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_15_1010 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1W7 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. http://togogenome.org/gene/420245:LBRM_19_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z448 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_35_3250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIW7 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/420245:LBRM_33_2900 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_11_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z097 ^@ Similarity ^@ Belongs to the WD repeat SEC31 family. http://togogenome.org/gene/420245:LBRM_35_5990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK14 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. http://togogenome.org/gene/420245:LBRM_09_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ59 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/420245:LBRM_34_0110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_35_3170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIP4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/420245:LBRM_27_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA92 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/420245:LBRM_26_1730 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9G2 ^@ Similarity ^@ Belongs to the MGMT family. http://togogenome.org/gene/420245:LBRM_21_1680 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6C5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/420245:LBRM_25_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8I4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/420245:LBRM_09_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/420245:LBRM_19_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3L5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_30_0390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC98 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_15_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z274 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/420245:LBRM_28_0120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_29_2820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCG8 ^@ Similarity ^@ Belongs to the IFT56 family. http://togogenome.org/gene/420245:LBRM_35_2410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIG2 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_35_6330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK42 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. http://togogenome.org/gene/420245:LBRM_11_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z096 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/420245:LBRM_33_1020 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFI6 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/420245:LBRM_34_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGJ4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_21_1290 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6H1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/420245:LBRM_25_1620 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8V4 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/420245:LBRM_35_4750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJL9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/420245:LBRM_06_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYB4 ^@ Similarity|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Homodimer. http://togogenome.org/gene/420245:LBRM_30_1130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCH8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_32_3820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFD7 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/420245:LBRM_10_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZX4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_22_1460 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z745 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/420245:LBRM_27_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAA3 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily. http://togogenome.org/gene/420245:LBRM_28_2330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_11_0330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_25_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8A2 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/420245:LBRM_26_0320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/420245:LBRM_34_3820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_19_1770 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z425 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_28_2090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB26 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/420245:LBRM_19_1180 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3U6 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/420245:LBRM_14_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1N7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL21 family. http://togogenome.org/gene/420245:LBRM_18_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z384 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/420245:LBRM_19_1710 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z483 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/420245:LBRM_30_2020 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCR6 ^@ Similarity ^@ Belongs to the CCDC25 family. http://togogenome.org/gene/420245:LBRM_34_0260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_34_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/420245:LBRM_19_0590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3P4 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/420245:LBRM_18_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3B8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/420245:LBRM_30_1370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCI4 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/420245:LBRM_35_3350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIR4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_30_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCK4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS30 family. http://togogenome.org/gene/420245:LBRM_34_3290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHK7 ^@ Function|||Subunit ^@ Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase VP55 that creates mRNA's poly(A) tail. In the presence of VP39, VP55 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.|||Methyltransferase activity: Monomer, poly(A) polymerase activity: Heterodimer composed of a catalytic component, VP55, and a processivity factor, VP39. Interacts with Rap94 and NPH-I; these interactions might help linking transcription to capping and polyadenylation. http://togogenome.org/gene/420245:LBRM_28_1380 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB08 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/420245:LBRM_35_3630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIU3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/420245:LBRM_32_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEG4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_28_2830 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/420245:LBRM_35_1950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIC3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/420245:LBRM_25_1440 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z925 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_2640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHJ2 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/420245:LBRM_28_2401 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBF2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/420245:LBRM_34_1360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/420245:LBRM_23_1750 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7C9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/420245:LBRM_28_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC13 family.|||nuclear pore complex http://togogenome.org/gene/420245:LBRM_16_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2J9 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_34_3350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_08_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC3 subfamily.|||Nucleus http://togogenome.org/gene/420245:LBRM_19_1320 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3V2 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/420245:LBRM_22_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_3190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHD6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/420245:LBRM_06_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY70 ^@ Similarity ^@ Belongs to the lipin family. http://togogenome.org/gene/420245:LBRM_35_4170 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reverse transcriptase family. Telomerase subfamily.|||Nucleus|||Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.|||telomere http://togogenome.org/gene/420245:LBRM_32_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEH6 ^@ Similarity ^@ Belongs to the proteasome subunit S14 family. http://togogenome.org/gene/420245:LBRM_27_2470 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA99 ^@ Similarity ^@ Belongs to the acyl-CoA oxidase family. http://togogenome.org/gene/420245:LBRM_35_5190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IMPACT family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_28_2010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAX4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).|||Cytoplasm http://togogenome.org/gene/420245:LBRM_06_1250 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_24_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7K0 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/420245:LBRM_26_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z921 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_28_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_28_2260 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/420245:LBRM_28_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAP8 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/420245:LBRM_35_7280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_25_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8M1 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_34_0430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGC7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/420245:LBRM_16_1360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2H8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/420245:LBRM_13_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z183 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_30_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCB7 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/420245:LBRM_23_0020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT11 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_25_0120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/420245:LBRM_34_1800 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_29_1610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_29_2280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC16 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/420245:LBRM_32_4130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_33_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFU9 ^@ Similarity ^@ Belongs to the NKAP family. http://togogenome.org/gene/420245:LBRM_28_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAQ8 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/420245:LBRM_29_2340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC08 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/420245:LBRM_14_0970 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Membrane|||Monomer. http://togogenome.org/gene/420245:LBRM_28_3070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB85 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/420245:LBRM_35_5340 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJA5 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/420245:LBRM_02_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWS5 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/420245:LBRM_05_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXV2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M49 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/420245:LBRM_35_6730 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/420245:LBRM_27_2430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAJ8 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/420245:LBRM_26_1850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9P4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_33_2040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPRBP/DCAF1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_14_0350 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1F0 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/420245:LBRM_26_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9C9 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/420245:LBRM_09_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CHFR family.|||PML body http://togogenome.org/gene/420245:LBRM_33_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS41 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_21_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z633 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_32_0240 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE57 ^@ Similarity ^@ Belongs to the U2 small nuclear ribonucleoprotein A family. http://togogenome.org/gene/420245:LBRM_07_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYF9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anamorsin family.|||Cytoplasm|||Mitochondrion intermembrane space|||Monomer. http://togogenome.org/gene/420245:LBRM_35_2600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZII3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. http://togogenome.org/gene/420245:LBRM_11_0790 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z082 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/420245:LBRM_35_1120 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI39 ^@ Subcellular Location Annotation ^@ cilium http://togogenome.org/gene/420245:LBRM_28_3230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB86 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/420245:LBRM_29_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_33_0860 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/420245:LBRM_26_1990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9F7 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/420245:LBRM_33_2670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGA2 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/420245:LBRM_19_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VPS36 family.|||Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II).|||Cytoplasm|||Endosome http://togogenome.org/gene/420245:LBRM_30_1550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCJ7 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_19_1470 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3Y2 ^@ Similarity ^@ Belongs to the pex2/pex10/pex12 family. http://togogenome.org/gene/420245:LBRM_34_5310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI69 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/420245:LBRM_23_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z741 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/420245:LBRM_35_1000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI21 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/420245:LBRM_35_4040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvT family.|||Mitochondrion|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/420245:LBRM_28_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_6620 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJQ4 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. http://togogenome.org/gene/420245:LBRM_34_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_13_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z156 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/420245:LBRM_31_3480 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_22_0090 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6I7 ^@ Similarity ^@ In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family. http://togogenome.org/gene/420245:LBRM_31_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBW8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/420245:LBRM_34_0370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGF0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/420245:LBRM_34_5040 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHN5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family. http://togogenome.org/gene/420245:LBRM_15_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_5790 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_05_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXQ4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_29_1810 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBU8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_28_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_1830 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFS0 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/420245:LBRM_33_0720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFR7 ^@ Similarity ^@ Belongs to the ERG4/ERG24 family. http://togogenome.org/gene/420245:LBRM_32_3680 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF65 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/420245:LBRM_29_1390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBP7 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/420245:LBRM_26_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9G0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_33_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFH3 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/420245:LBRM_31_3630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the histone H4 family.|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_23_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z762 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_34_3010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHB6 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_11_0710 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z080 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_28_2290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0220 family.|||Membrane http://togogenome.org/gene/420245:LBRM_07_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYN7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_27_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA40 ^@ Similarity ^@ Belongs to the diacylglycerol acyltransferase family. http://togogenome.org/gene/420245:LBRM_31_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDA2 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/420245:LBRM_11_0550 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0H3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS21 family. http://togogenome.org/gene/420245:LBRM_27_2010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAF3 ^@ Similarity ^@ In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family. http://togogenome.org/gene/420245:LBRM_11_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0I1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_35_7010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJU0 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/420245:LBRM_15_0930 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_24_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7G0 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/420245:LBRM_14_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1B0 ^@ Similarity ^@ Belongs to the SEC5 family. http://togogenome.org/gene/420245:LBRM_29_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/420245:LBRM_32_1190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEQ1 ^@ Similarity ^@ Belongs to the UPL family. K-HECT subfamily. http://togogenome.org/gene/420245:LBRM_17_1030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lariat debranching enzyme family.|||Nucleus http://togogenome.org/gene/420245:LBRM_30_3470 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD36 ^@ Similarity ^@ Belongs to the XPG/RAD2 endonuclease family. http://togogenome.org/gene/420245:LBRM_28_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAW1 ^@ Similarity ^@ Belongs to the SAS10 family. http://togogenome.org/gene/420245:LBRM_11_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z099 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_3990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHE0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_13_0930 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z100 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/420245:LBRM_21_0820 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/420245:LBRM_07_0280 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYE9 ^@ Similarity ^@ Belongs to the peptidase M20A family. ArgE subfamily. http://togogenome.org/gene/420245:LBRM_27_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNAAF3 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_16_0010 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_23_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z705 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_3840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. http://togogenome.org/gene/420245:LBRM_17_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z314 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/420245:LBRM_21_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z676 ^@ Similarity ^@ Belongs to the tubulin family. http://togogenome.org/gene/420245:LBRM_01_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWM0 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/420245:LBRM_09_1460 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZE9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/420245:LBRM_21_0030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z5U8 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/420245:LBRM_29_0960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/420245:LBRM_28_1670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_3860 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_16_1370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2G4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/420245:LBRM_21_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z697 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/420245:LBRM_03_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWY2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. http://togogenome.org/gene/420245:LBRM_30_1840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDB5 ^@ Caution|||Function|||Similarity ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/420245:LBRM_21_0810 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z624 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_04_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCO1/2 family.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_19_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z406 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/420245:LBRM_18_0520 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z395 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCB family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_30_0090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC85 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/420245:LBRM_23_1890 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXQ6 ^@ Similarity ^@ Belongs to the COG4 family. http://togogenome.org/gene/420245:LBRM_23_1700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7C5 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/420245:LBRM_13_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z123 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/420245:LBRM_24_2210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z818 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_30_0540 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCC4 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/420245:LBRM_30_0530 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCB6 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/420245:LBRM_26_2660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9R0 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/420245:LBRM_33_0290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG06 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/420245:LBRM_11_0950 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0B3 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/420245:LBRM_07_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYF4 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/420245:LBRM_25_1960 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8T6 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/420245:LBRM_32_0130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE52 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/420245:LBRM_31_3150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/420245:LBRM_34_1330 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH60 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_08_0890 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ53 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/420245:LBRM_29_2320 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCC6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_21_1410 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z693 ^@ Similarity ^@ Belongs to the thymidine kinase family. http://togogenome.org/gene/420245:LBRM_16_0810 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69.2) family.|||Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.|||Membrane http://togogenome.org/gene/420245:LBRM_29_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI5 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/420245:LBRM_21_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z646 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_18_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3E0 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/420245:LBRM_30_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCI6 ^@ Similarity ^@ Belongs to the bystin family. http://togogenome.org/gene/420245:LBRM_13_0200 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0R5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/420245:LBRM_29_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBM6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/420245:LBRM_25_1930 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8S3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_27_1600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAB2 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/420245:LBRM_29_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/420245:LBRM_14_1330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1J5 ^@ Similarity ^@ Belongs to the enolase family. http://togogenome.org/gene/420245:LBRM_25_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/420245:LBRM_18_1630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3K1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_21_0530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z694 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/420245:LBRM_05_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXW5 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/420245:LBRM_22_0060 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NFX1 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_28_1080 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAU5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/420245:LBRM_25_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8M0 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/420245:LBRM_12_0170 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the APH-1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_09_0420 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ48 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_25_1300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEN0 ^@ Similarity ^@ Belongs to the WD repeat SEC13 family. http://togogenome.org/gene/420245:LBRM_26_2370 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9U8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/420245:LBRM_33_1630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFZ3 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/420245:LBRM_19_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3N0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_03_0830 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX56 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/420245:LBRM_25_0610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8A2 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/420245:LBRM_35_6400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK31 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/420245:LBRM_31_3080 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/420245:LBRM_12_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0I7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/420245:LBRM_28_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAX1 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/420245:LBRM_13_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0U5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/420245:LBRM_32_2870 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEU9 ^@ Similarity ^@ Belongs to the iron/manganese superoxide dismutase family. http://togogenome.org/gene/420245:LBRM_24_1780 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z866 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/420245:LBRM_19_0110 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z056 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/420245:LBRM_33_1910 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGH3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.|||Cytoplasm|||May play a role in chaperone-mediated protein folding. http://togogenome.org/gene/420245:LBRM_10_0110 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZH4 ^@ Function|||Similarity ^@ Belongs to the WD repeat CIA1 family.|||Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. http://togogenome.org/gene/420245:LBRM_28_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAS6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/420245:LBRM_32_3230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFL5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_32_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEN8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_35_2950 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DTD family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_34_0360 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR9 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/420245:LBRM_16_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2A6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/420245:LBRM_28_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_13_1510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z167 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/420245:LBRM_27_0870 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCU (TC 1.A.77) family.|||Membrane|||Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_35_2060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIC4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Nucleus|||Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.|||The vault ribonucleoprotein particle is a huge (400 A x 670 A) cage structure of 12.9 MDa. It consists of a dimer of half-vaults, with each half-vault comprising 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). http://togogenome.org/gene/420245:LBRM_34_2630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHL4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/420245:LBRM_32_1750 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEJ6 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/420245:LBRM_15_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1U0 ^@ Similarity ^@ Belongs to the CMC family. http://togogenome.org/gene/420245:LBRM_34_3200 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHD6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/420245:LBRM_34_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGD7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/420245:LBRM_34_1980 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH80 ^@ Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM188 subfamily. http://togogenome.org/gene/420245:LBRM_27_2520 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Cytoplasm|||Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.|||Monomer. http://togogenome.org/gene/420245:LBRM_35_1860 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIT5 ^@ Function|||Similarity ^@ Belongs to the queuosine salvage protein family.|||Involved in salvaging queuosine. http://togogenome.org/gene/420245:LBRM_05_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/420245:LBRM_23_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_19_1820 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z492 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/420245:LBRM_30_1670 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_14_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_3590 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/420245:LBRM_18_1050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3K2 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/420245:LBRM_06_1030 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYC0 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/420245:LBRM_26_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9D6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/420245:LBRM_32_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE85 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/420245:LBRM_34_3730 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHP2 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/420245:LBRM_29_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBL3 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/420245:LBRM_34_1000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGK7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_30_3630 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD76 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/420245:LBRM_24_2340 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z833 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/420245:LBRM_31_3610 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEH8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_07_1200 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYN1 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/420245:LBRM_27_1880 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCC family.|||centrosome|||spindle pole http://togogenome.org/gene/420245:LBRM_04_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXH2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/420245:LBRM_24_1450 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7T5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_19_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_14_0980 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_5090 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_28_2030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0602 family.|||centrosome http://togogenome.org/gene/420245:LBRM_28_3030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBD3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/420245:LBRM_27_2220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFX0 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/420245:LBRM_11_0290 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.|||Membrane http://togogenome.org/gene/420245:LBRM_16_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2I2 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/420245:LBRM_22_0510 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6U7 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_33_1110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG98 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/420245:LBRM_09_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ25 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/420245:LBRM_28_2760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBI3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/420245:LBRM_19_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3Q0 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/420245:LBRM_05_0290 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_10_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZV8 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/420245:LBRM_23_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z720 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/420245:LBRM_34_4100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HDDC2 family.|||Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).|||Homodimer. http://togogenome.org/gene/420245:LBRM_26_0200 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z997 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.|||Nucleus http://togogenome.org/gene/420245:LBRM_06_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXY6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_35_0190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHU0 ^@ Similarity ^@ In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family. http://togogenome.org/gene/420245:LBRM_34_3640 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/420245:LBRM_34_5270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHT0 ^@ Subunit ^@ Homooctamer. Dimer of tetramers. http://togogenome.org/gene/420245:LBRM_29_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_35_2110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZID1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC4 family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_34_1220 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGL6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/420245:LBRM_10_0380 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_34_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/420245:LBRM_14_0250 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/420245:LBRM_27_1210 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZA44 ^@ Similarity ^@ Belongs to the TSR2 family. http://togogenome.org/gene/420245:LBRM_25_1810 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8X7 ^@ Similarity ^@ Belongs to the pex2/pex10/pex12 family. http://togogenome.org/gene/420245:LBRM_18_1350 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_30_1010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCF3 ^@ Function|||Similarity ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/420245:LBRM_18_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/420245:LBRM_30_0240 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_23_0080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6Z9 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/420245:LBRM_22_0560 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_25_1790 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_35_1840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_27_1310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9Y6 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/420245:LBRM_13_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/420245:LBRM_25_0260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z869 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/420245:LBRM_27_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9U0 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA mutase family. http://togogenome.org/gene/420245:LBRM_21_2030 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6F3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/420245:LBRM_35_0840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI01 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/420245:LBRM_34_3850 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHI4 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/420245:LBRM_03_0450 ^@ http://purl.uniprot.org/uniprot/A0A3P3YX15 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_34_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH00 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/420245:LBRM_13_0100 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/420245:LBRM_28_3140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZB84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_18_0690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z383 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/420245:LBRM_21_2010 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. http://togogenome.org/gene/420245:LBRM_26_1720 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9H1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HEATR1/UTP10 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/420245:LBRM_07_0200 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_34_0780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH44 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/420245:LBRM_29_2310 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZC25 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/420245:LBRM_31_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDJ4 ^@ Similarity ^@ Belongs to the dynein heavy chain family. http://togogenome.org/gene/420245:LBRM_32_0970 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGD7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/420245:LBRM_16_0750 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z298 ^@ Function|||Similarity ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. http://togogenome.org/gene/420245:LBRM_25_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8J5 ^@ Similarity ^@ Belongs to the SLBP family. http://togogenome.org/gene/420245:LBRM_34_5030 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHM9 ^@ Similarity ^@ Belongs to the PPR family. P subfamily. http://togogenome.org/gene/420245:LBRM_33_3510 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG96 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/420245:LBRM_29_1720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_32_3140 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFA8 ^@ Similarity ^@ Belongs to the SNAP family. http://togogenome.org/gene/420245:LBRM_06_0040 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL46 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_32_0820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZED0 ^@ Similarity ^@ Belongs to the DNAAF1 family. http://togogenome.org/gene/420245:LBRM_31_2960 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride exporter Fluc/FEX family.|||Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.|||Membrane http://togogenome.org/gene/420245:LBRM_24_1690 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z888 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_25_1530 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8N0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_29_0150 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/420245:LBRM_35_7380 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/420245:LBRM_26_0480 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z958 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/420245:LBRM_09_0070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYZ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/420245:LBRM_09_0920 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ86 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/420245:LBRM_10_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZP5 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/420245:LBRM_34_2940 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_34_4390 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.|||Membrane http://togogenome.org/gene/420245:LBRM_23_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z765 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/420245:LBRM_35_0550 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIE9 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/420245:LBRM_27_2690 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Nucleus|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. http://togogenome.org/gene/420245:LBRM_32_1490 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF48 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/420245:LBRM_35_5370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/420245:LBRM_27_0660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9V6 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/420245:LBRM_34_2190 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_07_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYM8 ^@ Similarity|||Subunit ^@ Belongs to the helicase family. PIF1 subfamily.|||Monomer. http://togogenome.org/gene/420245:LBRM_26_1240 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z951 ^@ Similarity ^@ Belongs to the DNAAF1 family. http://togogenome.org/gene/420245:LBRM_19_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/420245:LBRM_28_0540 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAG1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/420245:LBRM_32_1010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/420245:LBRM_19_1020 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3T2 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/420245:LBRM_27_2230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAH3 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/420245:LBRM_32_0500 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7M1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/420245:LBRM_35_0600 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_19_1890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z423 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/420245:LBRM_30_3580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD54 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/420245:LBRM_25_1660 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal TPase family.|||Nucleus http://togogenome.org/gene/420245:LBRM_14_1440 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1K5 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/420245:LBRM_16_0630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z278 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_15_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/420245:LBRM_28_2230 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAY4 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/420245:LBRM_07_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYM2 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/420245:LBRM_28_2580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/420245:LBRM_23_1590 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7B5 ^@ Similarity ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family. http://togogenome.org/gene/420245:LBRM_31_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZD88 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/420245:LBRM_29_1840 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBW2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_21_0740 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z619 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/420245:LBRM_19_1360 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/420245:LBRM_13_0340 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z0T4 ^@ Similarity ^@ Belongs to the CCDC124 family. http://togogenome.org/gene/420245:LBRM_35_0400 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/420245:LBRM_09_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PET117 family.|||Mitochondrion http://togogenome.org/gene/420245:LBRM_35_1010 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/420245:LBRM_21_0700 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z614 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/420245:LBRM_35_2280 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIF6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/420245:LBRM_10_0410 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/420245:LBRM_35_3490 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJ54 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/420245:LBRM_19_0490 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3N3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_30_1060 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/420245:LBRM_18_1650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/420245:LBRM_18_1140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3I3 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/420245:LBRM_35_1290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI51 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/420245:LBRM_35_3990 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3F9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/420245:LBRM_06_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYB2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_33_3460 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/420245:LBRM_19_0140 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z024 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_26_0050 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z904 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvP family.|||Mitochondrion|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/420245:LBRM_34_1790 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZGS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/420245:LBRM_31_0270 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDC0 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/420245:LBRM_32_0470 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZE73 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.|||Belongs to the DEAD box helicase family. eIF4A subfamily.|||eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G. http://togogenome.org/gene/420245:LBRM_34_3160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZH53 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/420245:LBRM_16_1430 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2H1 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_35_4440 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS2/PSF2 family.|||Nucleus http://togogenome.org/gene/420245:LBRM_33_0900 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the peroxisomal translocation machinery.|||Peroxisome membrane http://togogenome.org/gene/420245:LBRM_09_0990 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZ96 ^@ Similarity ^@ Belongs to the NEMF family. http://togogenome.org/gene/420245:LBRM_35_1100 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIA3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/420245:LBRM_29_1820 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBU8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_32_0580 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEV9 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/420245:LBRM_10_1260 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z074 ^@ Similarity ^@ Belongs to the CFAP45 family. http://togogenome.org/gene/420245:LBRM_15_0120 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/420245:LBRM_17_0160 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/420245:LBRM_11_0230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z734 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/420245:LBRM_33_1160 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZFL4 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/420245:LBRM_23_1640 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/420245:LBRM_32_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/420245:LBRM_14_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/420245:LBRM_33_0130 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZF93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP19 family.|||centriole|||cilium basal body http://togogenome.org/gene/420245:LBRM_27_2370 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/420245:LBRM_16_1670 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/420245:LBRM_26_2630 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9R0 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/420245:LBRM_15_0210 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z1Z7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/420245:LBRM_15_1230 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z213 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/420245:LBRM_19_0860 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3R8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/420245:LBRM_18_1610 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3K6 ^@ Similarity ^@ Belongs to the IUNH family. http://togogenome.org/gene/420245:LBRM_22_1080 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6S3 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/420245:LBRM_28_2020 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAX5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_24_0650 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z7L5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_31_2290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZDU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Component of the 60S subunit of the ribosome.|||Cytoplasm|||Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus|||Ribosomal protein L40 is part of the 60S ribosomal subunit. http://togogenome.org/gene/420245:LBRM_35_6350 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZJZ6 ^@ Similarity ^@ Belongs to the COG2 family. http://togogenome.org/gene/420245:LBRM_29_0770 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZBR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPP10 family.|||nucleolus http://togogenome.org/gene/420245:LBRM_02_0640 ^@ http://purl.uniprot.org/uniprot/A0A3P3YWY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP14 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.|||nucleolus http://togogenome.org/gene/420245:LBRM_33_3500 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZG88 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_10_0310 ^@ http://purl.uniprot.org/uniprot/A0A3P3YZJ2 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/420245:LBRM_33_0890 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. http://togogenome.org/gene/420245:LBRM_06_0870 ^@ http://purl.uniprot.org/uniprot/A0A3P3YY81 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/420245:LBRM_35_0760 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI00 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/420245:LBRM_26_1400 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z974 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/420245:LBRM_35_1780 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin heavy chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/420245:LBRM_17_0810 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z2W5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/420245:LBRM_35_1110 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIA3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/420245:LBRM_26_1640 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/420245:LBRM_23_0330 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z6Z4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/420245:LBRM_21_1150 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z655 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/420245:LBRM_27_0670 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z9S4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/420245:LBRM_15_0850 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z271 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/420245:LBRM_25_1760 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z8R3 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/420245:LBRM_04_0570 ^@ http://purl.uniprot.org/uniprot/A0A3P3YXD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/420245:LBRM_34_2790 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZHF6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/420245:LBRM_32_2000 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZEL6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/420245:LBRM_18_0880 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z3A0 ^@ Similarity ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family. http://togogenome.org/gene/420245:LBRM_28_1290 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZAQ2 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/420245:LBRM_35_6430 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZK03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.|||Cytoplasm|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. http://togogenome.org/gene/420245:LBRM_11_0300 ^@ http://purl.uniprot.org/uniprot/A0A3P3Z046 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/420245:LBRM_30_1070 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZCF1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/420245:LBRM_07_0800 ^@ http://purl.uniprot.org/uniprot/A0A3P3YYS9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/420245:LBRM_35_0940 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZI14 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/420245:LBRM_35_3720 ^@ http://purl.uniprot.org/uniprot/A0A3P3ZIV8 ^@ Similarity ^@ Belongs to the CFAP298 family.