http://togogenome.org/gene/479434:STHE_RS02280 ^@ http://purl.uniprot.org/uniprot/D1C7R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/479434:STHE_RS03855 ^@ http://purl.uniprot.org/uniprot/D1C1U2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS03945 ^@ http://purl.uniprot.org/uniprot/D1C1V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/479434:STHE_RS02810 ^@ http://purl.uniprot.org/uniprot/D1C187 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/479434:STHE_RS06000 ^@ http://purl.uniprot.org/uniprot/D1C313 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/479434:STHE_RS07365 ^@ http://purl.uniprot.org/uniprot/D1C3S6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS00165 ^@ http://purl.uniprot.org/uniprot/D1C5F7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/479434:STHE_RS03125 ^@ http://purl.uniprot.org/uniprot/D1C1F0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/479434:STHE_RS16900 ^@ http://purl.uniprot.org/uniprot/D1CAE3 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/479434:STHE_RS05025 ^@ http://purl.uniprot.org/uniprot/D1C2H0 ^@ Function|||Similarity ^@ 3'-5' exonuclease.|||Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily. http://togogenome.org/gene/479434:STHE_RS00550 ^@ http://purl.uniprot.org/uniprot/D1C5N5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/479434:STHE_RS09930 ^@ http://purl.uniprot.org/uniprot/D1C582 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/479434:STHE_RS06285 ^@ http://purl.uniprot.org/uniprot/D1C370 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS14315 ^@ http://purl.uniprot.org/uniprot/D1C8X6 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS04265 ^@ http://purl.uniprot.org/uniprot/D1C224 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/479434:STHE_RS16230 ^@ http://purl.uniprot.org/uniprot/D1CA03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07435 ^@ http://purl.uniprot.org/uniprot/D1C3U0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS07240 ^@ http://purl.uniprot.org/uniprot/D1C3Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/479434:STHE_RS05710 ^@ http://purl.uniprot.org/uniprot/D1C2V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS13595 ^@ http://purl.uniprot.org/uniprot/D1C8I5 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/479434:STHE_RS14750 ^@ http://purl.uniprot.org/uniprot/D1C955 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/479434:STHE_RS01080 ^@ http://purl.uniprot.org/uniprot/D1C6C0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS12900 ^@ http://purl.uniprot.org/uniprot/D1C849 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS07685 ^@ http://purl.uniprot.org/uniprot/D1C3Z2 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/479434:STHE_RS13370 ^@ http://purl.uniprot.org/uniprot/D1C8E0 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/479434:STHE_RS03360 ^@ http://purl.uniprot.org/uniprot/D1C1J7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS02635 ^@ http://purl.uniprot.org/uniprot/D1C152 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS03605 ^@ http://purl.uniprot.org/uniprot/D1C1P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS15885 ^@ http://purl.uniprot.org/uniprot/D1C9T3 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/479434:STHE_RS07225 ^@ http://purl.uniprot.org/uniprot/D1C3P7 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS01545 ^@ http://purl.uniprot.org/uniprot/D1C6Z4 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/479434:STHE_RS08990 ^@ http://purl.uniprot.org/uniprot/D1C4P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10050 ^@ http://purl.uniprot.org/uniprot/D1C5A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08145 ^@ http://purl.uniprot.org/uniprot/D1C476 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/479434:STHE_RS08230 ^@ http://purl.uniprot.org/uniprot/D1C491 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08745 ^@ http://purl.uniprot.org/uniprot/D1C4J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/479434:STHE_RS04180 ^@ http://purl.uniprot.org/uniprot/D1C207 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/479434:STHE_RS09570 ^@ http://purl.uniprot.org/uniprot/D1C510 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS01375 ^@ http://purl.uniprot.org/uniprot/D1C6V9 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/479434:STHE_RS07050 ^@ http://purl.uniprot.org/uniprot/D1C3L2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/479434:STHE_RS12265 ^@ http://purl.uniprot.org/uniprot/D1C7Z3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS15100 ^@ http://purl.uniprot.org/uniprot/D1C9C5 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.|||Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA). http://togogenome.org/gene/479434:STHE_RS04745 ^@ http://purl.uniprot.org/uniprot/D1C2B5 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/479434:STHE_RS14975 ^@ http://purl.uniprot.org/uniprot/D1C9A0 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/479434:STHE_RS14045 ^@ http://purl.uniprot.org/uniprot/D1C8S4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS06965 ^@ http://purl.uniprot.org/uniprot/D1C3J5 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/479434:STHE_RS11805 ^@ http://purl.uniprot.org/uniprot/D1C7C8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS15750 ^@ http://purl.uniprot.org/uniprot/D1C9Q6 ^@ Similarity|||Subunit ^@ Belongs to the multicopper oxidase family.|||Homotrimer. http://togogenome.org/gene/479434:STHE_RS15980 ^@ http://purl.uniprot.org/uniprot/D1C9V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS02990 ^@ http://purl.uniprot.org/uniprot/D1C1C3 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/479434:STHE_RS01320 ^@ http://purl.uniprot.org/uniprot/D1C6U7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/479434:STHE_RS11895 ^@ http://purl.uniprot.org/uniprot/D1C7E5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/479434:STHE_RS02190 ^@ http://purl.uniprot.org/uniprot/D1C7Q2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/479434:STHE_RS04630 ^@ http://purl.uniprot.org/uniprot/D1C293 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/479434:STHE_RS06325 ^@ http://purl.uniprot.org/uniprot/D1C378 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/479434:STHE_RS09605 ^@ http://purl.uniprot.org/uniprot/D1C517 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/479434:STHE_RS00710 ^@ http://purl.uniprot.org/uniprot/D1C646 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/479434:STHE_RS11430 ^@ http://purl.uniprot.org/uniprot/D1C752 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS17380 ^@ http://purl.uniprot.org/uniprot/D1CAN7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/479434:STHE_RS12950 ^@ http://purl.uniprot.org/uniprot/D1C855 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/479434:STHE_RS05950 ^@ http://purl.uniprot.org/uniprot/D1C303 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/479434:STHE_RS10945 ^@ http://purl.uniprot.org/uniprot/D1C6H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS11670 ^@ http://purl.uniprot.org/uniprot/D1C7A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS00610 ^@ http://purl.uniprot.org/uniprot/D1C625 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02145 ^@ http://purl.uniprot.org/uniprot/D1C7P2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/479434:STHE_RS09300 ^@ http://purl.uniprot.org/uniprot/D1C4V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS13125 ^@ http://purl.uniprot.org/uniprot/D1C890 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/479434:STHE_RS07150 ^@ http://purl.uniprot.org/uniprot/D1C3N2 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/479434:STHE_RS00830 ^@ http://purl.uniprot.org/uniprot/D1C670 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS08625 ^@ http://purl.uniprot.org/uniprot/D1C4H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS15175 ^@ http://purl.uniprot.org/uniprot/D1C9D9 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/479434:STHE_RS01855 ^@ http://purl.uniprot.org/uniprot/D1C7I4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS02875 ^@ http://purl.uniprot.org/uniprot/D1C1A1 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/479434:STHE_RS05940 ^@ http://purl.uniprot.org/uniprot/D1C301 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/479434:STHE_RS19290 ^@ http://purl.uniprot.org/uniprot/D1C5C6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS13285 ^@ http://purl.uniprot.org/uniprot/D1C8C3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/479434:STHE_RS04590 ^@ http://purl.uniprot.org/uniprot/D1C285 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/479434:STHE_RS13090 ^@ http://purl.uniprot.org/uniprot/D1C883 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the CofC family.|||Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.|||The exact nature of the substrate is currently not known. This entry has been annotated based on its similarity to Actinobacteria. http://togogenome.org/gene/479434:STHE_RS01570 ^@ http://purl.uniprot.org/uniprot/D1C6Z9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/479434:STHE_RS06290 ^@ http://purl.uniprot.org/uniprot/D1C371 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS07395 ^@ http://purl.uniprot.org/uniprot/D1C3T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/479434:STHE_RS01190 ^@ http://purl.uniprot.org/uniprot/D1C6E2 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/479434:STHE_RS05560 ^@ http://purl.uniprot.org/uniprot/D1C2S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS08545 ^@ http://purl.uniprot.org/uniprot/D1C4F5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates ribosomal protein L11. http://togogenome.org/gene/479434:STHE_RS07290 ^@ http://purl.uniprot.org/uniprot/D1C3R0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS12785 ^@ http://purl.uniprot.org/uniprot/D1C826 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS05650 ^@ http://purl.uniprot.org/uniprot/D1C2U5 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/479434:STHE_RS09245 ^@ http://purl.uniprot.org/uniprot/D1C4U5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/479434:STHE_RS12225 ^@ http://purl.uniprot.org/uniprot/D1C7Y4 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/479434:STHE_RS05580 ^@ http://purl.uniprot.org/uniprot/D1C2T1 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/479434:STHE_RS08480 ^@ http://purl.uniprot.org/uniprot/D1C4E2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/479434:STHE_RS04540 ^@ http://purl.uniprot.org/uniprot/D1C275 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/479434:STHE_RS03625 ^@ http://purl.uniprot.org/uniprot/D1C1Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/479434:STHE_RS10820 ^@ http://purl.uniprot.org/uniprot/D1C6F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02560 ^@ http://purl.uniprot.org/uniprot/D1C137 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/479434:STHE_RS04610 ^@ http://purl.uniprot.org/uniprot/D1C289 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/479434:STHE_RS00705 ^@ http://purl.uniprot.org/uniprot/D1C645 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/479434:STHE_RS13255 ^@ http://purl.uniprot.org/uniprot/D1C8B7 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/479434:STHE_RS13610 ^@ http://purl.uniprot.org/uniprot/D1C8I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS17785 ^@ http://purl.uniprot.org/uniprot/D1C1S6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05170 ^@ http://purl.uniprot.org/uniprot/D1C2K1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/479434:STHE_RS08375 ^@ http://purl.uniprot.org/uniprot/D1C4B9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS18270 ^@ http://purl.uniprot.org/uniprot/D1C9X8 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/479434:STHE_RS09845 ^@ http://purl.uniprot.org/uniprot/D1C565 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/479434:STHE_RS06895 ^@ http://purl.uniprot.org/uniprot/D1C3I3 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/479434:STHE_RS09375 ^@ http://purl.uniprot.org/uniprot/D1C4X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14275 ^@ http://purl.uniprot.org/uniprot/D1C8W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06660 ^@ http://purl.uniprot.org/uniprot/D1C3E0 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/479434:STHE_RS07195 ^@ http://purl.uniprot.org/uniprot/D1C3P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/479434:STHE_RS09125 ^@ http://purl.uniprot.org/uniprot/D1C4S1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/479434:STHE_RS16505 ^@ http://purl.uniprot.org/uniprot/D1CA60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS17175 ^@ http://purl.uniprot.org/uniprot/D1CAJ6 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/479434:STHE_RS08440 ^@ http://purl.uniprot.org/uniprot/D1C4D3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS00790 ^@ http://purl.uniprot.org/uniprot/D1C662 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14790 ^@ http://purl.uniprot.org/uniprot/D1C964 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS17520 ^@ http://purl.uniprot.org/uniprot/D1CAR5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/479434:STHE_RS17320 ^@ http://purl.uniprot.org/uniprot/D1CAM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS02710 ^@ http://purl.uniprot.org/uniprot/D1C167 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15235 ^@ http://purl.uniprot.org/uniprot/D1C9F2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS16820 ^@ http://purl.uniprot.org/uniprot/D1CAC7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/479434:STHE_RS07530 ^@ http://purl.uniprot.org/uniprot/D1C3W1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS15660 ^@ http://purl.uniprot.org/uniprot/D1C9N8 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/479434:STHE_RS14795 ^@ http://purl.uniprot.org/uniprot/D1C965 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08020 ^@ http://purl.uniprot.org/uniprot/D1C452 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS13660 ^@ http://purl.uniprot.org/uniprot/D1C8J7 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/479434:STHE_RS06235 ^@ http://purl.uniprot.org/uniprot/D1C360 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS10055 ^@ http://purl.uniprot.org/uniprot/D1C5A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02845 ^@ http://purl.uniprot.org/uniprot/D1C195 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/479434:STHE_RS16925 ^@ http://purl.uniprot.org/uniprot/D1CAE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/479434:STHE_RS08075 ^@ http://purl.uniprot.org/uniprot/D1C463 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/479434:STHE_RS04930 ^@ http://purl.uniprot.org/uniprot/D1C2F1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/479434:STHE_RS00285 ^@ http://purl.uniprot.org/uniprot/D1C5I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05550 ^@ http://purl.uniprot.org/uniprot/D1C2S6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS14900 ^@ http://purl.uniprot.org/uniprot/D1C985 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS03450 ^@ http://purl.uniprot.org/uniprot/D1C1L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS13535 ^@ http://purl.uniprot.org/uniprot/D1C8H3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10010 ^@ http://purl.uniprot.org/uniprot/D1C599 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/479434:STHE_RS05585 ^@ http://purl.uniprot.org/uniprot/D1C2T2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/479434:STHE_RS07820 ^@ http://purl.uniprot.org/uniprot/D1C419 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/479434:STHE_RS09640 ^@ http://purl.uniprot.org/uniprot/D1C524 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10815 ^@ http://purl.uniprot.org/uniprot/D1C6F1 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/479434:STHE_RS03980 ^@ http://purl.uniprot.org/uniprot/D1C1W6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/479434:STHE_RS05980 ^@ http://purl.uniprot.org/uniprot/D1C309 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06855 ^@ http://purl.uniprot.org/uniprot/D1C3H5 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/479434:STHE_RS09155 ^@ http://purl.uniprot.org/uniprot/D1C4S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS05910 ^@ http://purl.uniprot.org/uniprot/D1C2Z5 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/479434:STHE_RS12585 ^@ http://purl.uniprot.org/uniprot/D1CAY2 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/479434:STHE_RS03520 ^@ http://purl.uniprot.org/uniprot/D1C1M9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS07185 ^@ http://purl.uniprot.org/uniprot/D1C3N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/479434:STHE_RS11345 ^@ http://purl.uniprot.org/uniprot/D1C6Q4 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/479434:STHE_RS07200 ^@ http://purl.uniprot.org/uniprot/D1C3P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/479434:STHE_RS02840 ^@ http://purl.uniprot.org/uniprot/D1C194 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/479434:STHE_RS09025 ^@ http://purl.uniprot.org/uniprot/D1C4Q1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/479434:STHE_RS04410 ^@ http://purl.uniprot.org/uniprot/D1C252 ^@ Function|||Similarity ^@ Belongs to the gas vesicle protein type A family.|||Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. http://togogenome.org/gene/479434:STHE_RS07840 ^@ http://purl.uniprot.org/uniprot/D1C423 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS08060 ^@ http://purl.uniprot.org/uniprot/D1C460 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/479434:STHE_RS10545 ^@ http://purl.uniprot.org/uniprot/D1C5W9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS09525 ^@ http://purl.uniprot.org/uniprot/D1C501 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/479434:STHE_RS09345 ^@ http://purl.uniprot.org/uniprot/D1C4W5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/479434:STHE_RS11715 ^@ http://purl.uniprot.org/uniprot/D1C7B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/479434:STHE_RS10630 ^@ http://purl.uniprot.org/uniprot/D1C5Y6 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/479434:STHE_RS09280 ^@ http://purl.uniprot.org/uniprot/D1C4V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/479434:STHE_RS05570 ^@ http://purl.uniprot.org/uniprot/D1C2T0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/479434:STHE_RS00440 ^@ http://purl.uniprot.org/uniprot/D1C5L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08470 ^@ http://purl.uniprot.org/uniprot/D1C4E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS19200 ^@ http://purl.uniprot.org/uniprot/D1C3T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS12195 ^@ http://purl.uniprot.org/uniprot/D1C7X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/479434:STHE_RS03130 ^@ http://purl.uniprot.org/uniprot/D1C1F1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/479434:STHE_RS16240 ^@ http://purl.uniprot.org/uniprot/D1CA05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/479434:STHE_RS14335 ^@ http://purl.uniprot.org/uniprot/D1C8Y0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS11880 ^@ http://purl.uniprot.org/uniprot/D1C7E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS13375 ^@ http://purl.uniprot.org/uniprot/D1C8E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15215 ^@ http://purl.uniprot.org/uniprot/D1C9E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS15290 ^@ http://purl.uniprot.org/uniprot/D1C9G4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS14510 ^@ http://purl.uniprot.org/uniprot/D1C915 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/479434:STHE_RS03020 ^@ http://purl.uniprot.org/uniprot/D1C1C9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS10685 ^@ http://purl.uniprot.org/uniprot/D1C5Z8 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/479434:STHE_RS01850 ^@ http://purl.uniprot.org/uniprot/D1C7I3 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/479434:STHE_RS12565 ^@ http://purl.uniprot.org/uniprot/D1CAX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS00720 ^@ http://purl.uniprot.org/uniprot/D1C648 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS13960 ^@ http://purl.uniprot.org/uniprot/D1C8Q6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS01460 ^@ http://purl.uniprot.org/uniprot/D1C6X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS05065 ^@ http://purl.uniprot.org/uniprot/D1C2H8 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS14595 ^@ http://purl.uniprot.org/uniprot/D1C930 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/479434:STHE_RS04655 ^@ http://purl.uniprot.org/uniprot/D1C297 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04110 ^@ http://purl.uniprot.org/uniprot/D1C1Z3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS08405 ^@ http://purl.uniprot.org/uniprot/D1C4C6 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/479434:STHE_RS02085 ^@ http://purl.uniprot.org/uniprot/D1C7N0 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/479434:STHE_RS00800 ^@ http://purl.uniprot.org/uniprot/D1C664 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/479434:STHE_RS03740 ^@ http://purl.uniprot.org/uniprot/D1C1S2 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/479434:STHE_RS06400 ^@ http://purl.uniprot.org/uniprot/D1C391 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/479434:STHE_RS02575 ^@ http://purl.uniprot.org/uniprot/D1C140 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/479434:STHE_RS11770 ^@ http://purl.uniprot.org/uniprot/D1C7C1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS18680 ^@ http://purl.uniprot.org/uniprot/D1C128 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS08630 ^@ http://purl.uniprot.org/uniprot/D1C4H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02040 ^@ http://purl.uniprot.org/uniprot/D1C7M1 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/479434:STHE_RS11005 ^@ http://purl.uniprot.org/uniprot/D1C6I7 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/479434:STHE_RS16750 ^@ http://purl.uniprot.org/uniprot/D1CAB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS00005 ^@ http://purl.uniprot.org/uniprot/D1C5C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/479434:STHE_RS13935 ^@ http://purl.uniprot.org/uniprot/D1C8Q1 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/479434:STHE_RS08665 ^@ http://purl.uniprot.org/uniprot/D1C4H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/479434:STHE_RS07540 ^@ http://purl.uniprot.org/uniprot/D1C3W3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/479434:STHE_RS11675 ^@ http://purl.uniprot.org/uniprot/D1C7A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/479434:STHE_RS12280 ^@ http://purl.uniprot.org/uniprot/D1C7Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS18310 ^@ http://purl.uniprot.org/uniprot/D1CA78 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/479434:STHE_RS12430 ^@ http://purl.uniprot.org/uniprot/D1CAV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12835 ^@ http://purl.uniprot.org/uniprot/D1C836 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS17850 ^@ http://purl.uniprot.org/uniprot/D1C2X9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/479434:STHE_RS18055 ^@ http://purl.uniprot.org/uniprot/D1C6H5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS01675 ^@ http://purl.uniprot.org/uniprot/D1C720 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/479434:STHE_RS08120 ^@ http://purl.uniprot.org/uniprot/D1C471 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/479434:STHE_RS02835 ^@ http://purl.uniprot.org/uniprot/D1C193 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/479434:STHE_RS05535 ^@ http://purl.uniprot.org/uniprot/D1C2S3 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/479434:STHE_RS02630 ^@ http://purl.uniprot.org/uniprot/D1C151 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS10520 ^@ http://purl.uniprot.org/uniprot/D1C5W4 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/479434:STHE_RS02455 ^@ http://purl.uniprot.org/uniprot/D1C121 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/479434:STHE_RS15275 ^@ http://purl.uniprot.org/uniprot/D1C9G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03180 ^@ http://purl.uniprot.org/uniprot/D1C1G2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/479434:STHE_RS08050 ^@ http://purl.uniprot.org/uniprot/D1C458 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/479434:STHE_RS02735 ^@ http://purl.uniprot.org/uniprot/D1C172 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/479434:STHE_RS02890 ^@ http://purl.uniprot.org/uniprot/D1C1A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/479434:STHE_RS12395 ^@ http://purl.uniprot.org/uniprot/D1CAU4 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/479434:STHE_RS03060 ^@ http://purl.uniprot.org/uniprot/D1C1D7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/479434:STHE_RS10930 ^@ http://purl.uniprot.org/uniprot/D1C6H4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/479434:STHE_RS14690 ^@ http://purl.uniprot.org/uniprot/D1C945 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS11500 ^@ http://purl.uniprot.org/uniprot/D1C767 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/479434:STHE_RS00620 ^@ http://purl.uniprot.org/uniprot/D1C627 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/479434:STHE_RS05165 ^@ http://purl.uniprot.org/uniprot/D1C2K0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/479434:STHE_RS00310 ^@ http://purl.uniprot.org/uniprot/D1C5I6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/479434:STHE_RS14780 ^@ http://purl.uniprot.org/uniprot/D1C961 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/479434:STHE_RS03960 ^@ http://purl.uniprot.org/uniprot/D1C1W2 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/479434:STHE_RS12205 ^@ http://purl.uniprot.org/uniprot/D1C7Y0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS12070 ^@ http://purl.uniprot.org/uniprot/D1C7H7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS09180 ^@ http://purl.uniprot.org/uniprot/D1C4T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS09560 ^@ http://purl.uniprot.org/uniprot/D1C508 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS07265 ^@ http://purl.uniprot.org/uniprot/D1C3Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS02515 ^@ http://purl.uniprot.org/uniprot/D1C134 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS03455 ^@ http://purl.uniprot.org/uniprot/D1C1L6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS08520 ^@ http://purl.uniprot.org/uniprot/D1C4F0 ^@ Similarity ^@ Belongs to the LppX/LprAFG lipoprotein family. http://togogenome.org/gene/479434:STHE_RS07130 ^@ http://purl.uniprot.org/uniprot/D1C3M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/479434:STHE_RS09675 ^@ http://purl.uniprot.org/uniprot/D1C531 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08560 ^@ http://purl.uniprot.org/uniprot/D1C4F8 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/479434:STHE_RS04070 ^@ http://purl.uniprot.org/uniprot/D1C1Y4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS11455 ^@ http://purl.uniprot.org/uniprot/D1C757 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS00065 ^@ http://purl.uniprot.org/uniprot/D1C5D6 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/479434:STHE_RS08535 ^@ http://purl.uniprot.org/uniprot/D1C4F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS01450 ^@ http://purl.uniprot.org/uniprot/D1C6X5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS13790 ^@ http://purl.uniprot.org/uniprot/D1C8M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14035 ^@ http://purl.uniprot.org/uniprot/D1C8S2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/479434:STHE_RS05885 ^@ http://purl.uniprot.org/uniprot/D1C2Z0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/479434:STHE_RS09315 ^@ http://purl.uniprot.org/uniprot/D1C4V9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS11495 ^@ http://purl.uniprot.org/uniprot/D1C766 ^@ Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family. http://togogenome.org/gene/479434:STHE_RS00235 ^@ http://purl.uniprot.org/uniprot/D1C5H1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS01430 ^@ http://purl.uniprot.org/uniprot/D1C6X1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS06775 ^@ http://purl.uniprot.org/uniprot/D1C3G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS13540 ^@ http://purl.uniprot.org/uniprot/D1C8H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02005 ^@ http://purl.uniprot.org/uniprot/D1C7L4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/479434:STHE_RS01065 ^@ http://purl.uniprot.org/uniprot/D1C6B7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS05835 ^@ http://purl.uniprot.org/uniprot/D1C2Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/479434:STHE_RS01790 ^@ http://purl.uniprot.org/uniprot/D1C743 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS13455 ^@ http://purl.uniprot.org/uniprot/D1C8F7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/479434:STHE_RS05005 ^@ http://purl.uniprot.org/uniprot/D1C2G6 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/479434:STHE_RS09465 ^@ http://purl.uniprot.org/uniprot/D1C4Y9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/479434:STHE_RS04455 ^@ http://purl.uniprot.org/uniprot/D1C259 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/479434:STHE_RS09325 ^@ http://purl.uniprot.org/uniprot/D1C4W1 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/479434:STHE_RS03135 ^@ http://purl.uniprot.org/uniprot/D1C1F2 ^@ Similarity ^@ Belongs to the alkylbase DNA glycosidase AlkA family. http://togogenome.org/gene/479434:STHE_RS14340 ^@ http://purl.uniprot.org/uniprot/D1C8Y1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS06990 ^@ http://purl.uniprot.org/uniprot/D1C3K0 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/479434:STHE_RS15630 ^@ http://purl.uniprot.org/uniprot/D1C9N2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06795 ^@ http://purl.uniprot.org/uniprot/D1C3G5 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/479434:STHE_RS03190 ^@ http://purl.uniprot.org/uniprot/D1C1G5 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/479434:STHE_RS16680 ^@ http://purl.uniprot.org/uniprot/D1CA96 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/479434:STHE_RS04035 ^@ http://purl.uniprot.org/uniprot/D1C1X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS17695 ^@ http://purl.uniprot.org/uniprot/D1C7P5 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/479434:STHE_RS09130 ^@ http://purl.uniprot.org/uniprot/D1C4S2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/479434:STHE_RS02135 ^@ http://purl.uniprot.org/uniprot/D1C7P0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS03815 ^@ http://purl.uniprot.org/uniprot/D1C1T6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS06035 ^@ http://purl.uniprot.org/uniprot/D1C320 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS04910 ^@ http://purl.uniprot.org/uniprot/D1C2E7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/479434:STHE_RS02400 ^@ http://purl.uniprot.org/uniprot/D1C7U3 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/479434:STHE_RS02685 ^@ http://purl.uniprot.org/uniprot/D1C162 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/479434:STHE_RS15780 ^@ http://purl.uniprot.org/uniprot/D1C9R3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/479434:STHE_RS06420 ^@ http://purl.uniprot.org/uniprot/D1C395 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS03320 ^@ http://purl.uniprot.org/uniprot/D1C1J0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS17080 ^@ http://purl.uniprot.org/uniprot/D1CAH7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS06075 ^@ http://purl.uniprot.org/uniprot/D1C328 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/479434:STHE_RS00340 ^@ http://purl.uniprot.org/uniprot/D1C5J3 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/479434:STHE_RS13810 ^@ http://purl.uniprot.org/uniprot/D1C8M7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/479434:STHE_RS15835 ^@ http://purl.uniprot.org/uniprot/D1C9S3 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/479434:STHE_RS05000 ^@ http://purl.uniprot.org/uniprot/D1C2G5 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/479434:STHE_RS07040 ^@ http://purl.uniprot.org/uniprot/D1C3L0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/479434:STHE_RS05690 ^@ http://purl.uniprot.org/uniprot/D1C2V3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS10165 ^@ http://purl.uniprot.org/uniprot/D1C5P5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS04785 ^@ http://purl.uniprot.org/uniprot/D1C2C3 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/479434:STHE_RS08870 ^@ http://purl.uniprot.org/uniprot/D1C4L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/479434:STHE_RS13735 ^@ http://purl.uniprot.org/uniprot/D1C8L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06370 ^@ http://purl.uniprot.org/uniprot/D1C385 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/479434:STHE_RS02995 ^@ http://purl.uniprot.org/uniprot/D1C1C4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/479434:STHE_RS06495 ^@ http://purl.uniprot.org/uniprot/D1C3A8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/479434:STHE_RS08920 ^@ http://purl.uniprot.org/uniprot/D1C4N0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS05205 ^@ http://purl.uniprot.org/uniprot/D1C2K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/479434:STHE_RS01955 ^@ http://purl.uniprot.org/uniprot/D1C7K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS10810 ^@ http://purl.uniprot.org/uniprot/D1C6F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04970 ^@ http://purl.uniprot.org/uniprot/D1C2F9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/479434:STHE_RS02970 ^@ http://purl.uniprot.org/uniprot/D1C1B9 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/479434:STHE_RS06645 ^@ http://purl.uniprot.org/uniprot/D1C3D7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS13050 ^@ http://purl.uniprot.org/uniprot/D1C875 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS05325 ^@ http://purl.uniprot.org/uniprot/D1C2N2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/479434:STHE_RS16255 ^@ http://purl.uniprot.org/uniprot/D1CA08 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/479434:STHE_RS11465 ^@ http://purl.uniprot.org/uniprot/D1C759 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/479434:STHE_RS06505 ^@ http://purl.uniprot.org/uniprot/D1C3B0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/479434:STHE_RS18110 ^@ http://purl.uniprot.org/uniprot/D1C7Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS09470 ^@ http://purl.uniprot.org/uniprot/D1C4Z0 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/479434:STHE_RS14115 ^@ http://purl.uniprot.org/uniprot/D1C8T8 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/479434:STHE_RS09945 ^@ http://purl.uniprot.org/uniprot/D1C585 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/479434:STHE_RS01465 ^@ http://purl.uniprot.org/uniprot/D1C6X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS07015 ^@ http://purl.uniprot.org/uniprot/D1C3K5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/479434:STHE_RS07600 ^@ http://purl.uniprot.org/uniprot/D1C3X5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03075 ^@ http://purl.uniprot.org/uniprot/D1C1E0 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/479434:STHE_RS05210 ^@ http://purl.uniprot.org/uniprot/D1C2K9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/479434:STHE_RS05330 ^@ http://purl.uniprot.org/uniprot/D1C2N3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/479434:STHE_RS04725 ^@ http://purl.uniprot.org/uniprot/D1C2B1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/479434:STHE_RS15115 ^@ http://purl.uniprot.org/uniprot/D1C9C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/479434:STHE_RS03470 ^@ http://purl.uniprot.org/uniprot/D1C1L9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/479434:STHE_RS01495 ^@ http://purl.uniprot.org/uniprot/D1C6Y4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS15555 ^@ http://purl.uniprot.org/uniprot/D1C9L6 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS17250 ^@ http://purl.uniprot.org/uniprot/D1CAL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06875 ^@ http://purl.uniprot.org/uniprot/D1C3H9 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/479434:STHE_RS05625 ^@ http://purl.uniprot.org/uniprot/D1C2U0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/479434:STHE_RS05985 ^@ http://purl.uniprot.org/uniprot/D1C310 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/479434:STHE_RS14025 ^@ http://purl.uniprot.org/uniprot/D1C8S0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16485 ^@ http://purl.uniprot.org/uniprot/D1CA56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS17365 ^@ http://purl.uniprot.org/uniprot/D1CAN4 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/479434:STHE_RS15600 ^@ http://purl.uniprot.org/uniprot/D1C9M6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/479434:STHE_RS13060 ^@ http://purl.uniprot.org/uniprot/D1C877 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/479434:STHE_RS04895 ^@ http://purl.uniprot.org/uniprot/D1C2E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS12725 ^@ http://purl.uniprot.org/uniprot/D1C814 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/479434:STHE_RS08785 ^@ http://purl.uniprot.org/uniprot/D1C4K1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/479434:STHE_RS10675 ^@ http://purl.uniprot.org/uniprot/D1C5Z6 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/479434:STHE_RS00670 ^@ http://purl.uniprot.org/uniprot/D1C638 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS16700 ^@ http://purl.uniprot.org/uniprot/D1CAA2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS04705 ^@ http://purl.uniprot.org/uniprot/D1C2A7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS17795 ^@ http://purl.uniprot.org/uniprot/D1C1U5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/479434:STHE_RS13210 ^@ http://purl.uniprot.org/uniprot/D1C8A7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/479434:STHE_RS11085 ^@ http://purl.uniprot.org/uniprot/D1C6K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS13185 ^@ http://purl.uniprot.org/uniprot/D1C8A2 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/479434:STHE_RS07835 ^@ http://purl.uniprot.org/uniprot/D1C422 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/479434:STHE_RS17725 ^@ http://purl.uniprot.org/uniprot/D1C155 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS04245 ^@ http://purl.uniprot.org/uniprot/D1C220 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09120 ^@ http://purl.uniprot.org/uniprot/D1C4S0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/479434:STHE_RS01865 ^@ http://purl.uniprot.org/uniprot/D1C7I6 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/479434:STHE_RS00470 ^@ http://purl.uniprot.org/uniprot/D1C5L9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome|||Secreted http://togogenome.org/gene/479434:STHE_RS06005 ^@ http://purl.uniprot.org/uniprot/D1C314 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/479434:STHE_RS02405 ^@ http://purl.uniprot.org/uniprot/D1C7U4 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS08570 ^@ http://purl.uniprot.org/uniprot/D1C4G0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/479434:STHE_RS15070 ^@ http://purl.uniprot.org/uniprot/D1C9B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS15815 ^@ http://purl.uniprot.org/uniprot/D1C9R9 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/479434:STHE_RS01915 ^@ http://purl.uniprot.org/uniprot/D1C7J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02255 ^@ http://purl.uniprot.org/uniprot/D1C7R4 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/479434:STHE_RS03555 ^@ http://purl.uniprot.org/uniprot/D1C1N6 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/479434:STHE_RS08100 ^@ http://purl.uniprot.org/uniprot/D1C468 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/479434:STHE_RS02580 ^@ http://purl.uniprot.org/uniprot/D1C141 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05490 ^@ http://purl.uniprot.org/uniprot/D1C2R4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS04965 ^@ http://purl.uniprot.org/uniprot/D1C2F8 ^@ Function|||Similarity ^@ Belongs to the peptidase S9C family.|||This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. http://togogenome.org/gene/479434:STHE_RS04835 ^@ http://purl.uniprot.org/uniprot/D1C2D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04715 ^@ http://purl.uniprot.org/uniprot/D1C2A9 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/479434:STHE_RS13480 ^@ http://purl.uniprot.org/uniprot/D1C8G2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/479434:STHE_RS08655 ^@ http://purl.uniprot.org/uniprot/D1C4H6 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/479434:STHE_RS13025 ^@ http://purl.uniprot.org/uniprot/D1C870 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS01825 ^@ http://purl.uniprot.org/uniprot/D1C7H8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/479434:STHE_RS14860 ^@ http://purl.uniprot.org/uniprot/D1C978 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/479434:STHE_RS18150 ^@ http://purl.uniprot.org/uniprot/D1C8D1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/479434:STHE_RS16090 ^@ http://purl.uniprot.org/uniprot/D1C9X5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS00755 ^@ http://purl.uniprot.org/uniprot/D1C655 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07635 ^@ http://purl.uniprot.org/uniprot/D1C3Y2 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/479434:STHE_RS01650 ^@ http://purl.uniprot.org/uniprot/D1C715 ^@ Function ^@ Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). http://togogenome.org/gene/479434:STHE_RS05185 ^@ http://purl.uniprot.org/uniprot/D1C2K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS04890 ^@ http://purl.uniprot.org/uniprot/D1C2E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15825 ^@ http://purl.uniprot.org/uniprot/D1C9S1 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/479434:STHE_RS09070 ^@ http://purl.uniprot.org/uniprot/D1C4R0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS14280 ^@ http://purl.uniprot.org/uniprot/D1C8W9 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/479434:STHE_RS00640 ^@ http://purl.uniprot.org/uniprot/D1C631 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/479434:STHE_RS05755 ^@ http://purl.uniprot.org/uniprot/D1C2W6 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/479434:STHE_RS01860 ^@ http://purl.uniprot.org/uniprot/D1C7I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/479434:STHE_RS06765 ^@ http://purl.uniprot.org/uniprot/D1C3F9 ^@ Similarity ^@ Belongs to the selenium-binding protein family. http://togogenome.org/gene/479434:STHE_RS07285 ^@ http://purl.uniprot.org/uniprot/D1C3Q9 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/479434:STHE_RS10745 ^@ http://purl.uniprot.org/uniprot/D1C610 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10380 ^@ http://purl.uniprot.org/uniprot/D1C5U0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/479434:STHE_RS10840 ^@ http://purl.uniprot.org/uniprot/D1C6F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/479434:STHE_RS06750 ^@ http://purl.uniprot.org/uniprot/D1C3F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS11865 ^@ http://purl.uniprot.org/uniprot/D1C7D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/479434:STHE_RS16310 ^@ http://purl.uniprot.org/uniprot/D1CA21 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS02170 ^@ http://purl.uniprot.org/uniprot/D1C7P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/479434:STHE_RS06275 ^@ http://purl.uniprot.org/uniprot/D1C368 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/479434:STHE_RS08275 ^@ http://purl.uniprot.org/uniprot/D1C499 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/479434:STHE_RS15560 ^@ http://purl.uniprot.org/uniprot/D1C9L8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/479434:STHE_RS08940 ^@ http://purl.uniprot.org/uniprot/D1C4N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16140 ^@ http://purl.uniprot.org/uniprot/D1C9Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS03595 ^@ http://purl.uniprot.org/uniprot/D1C1P4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS07155 ^@ http://purl.uniprot.org/uniprot/D1C3N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS11090 ^@ http://purl.uniprot.org/uniprot/D1C6K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09625 ^@ http://purl.uniprot.org/uniprot/D1C521 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/479434:STHE_RS16215 ^@ http://purl.uniprot.org/uniprot/D1CA00 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family. http://togogenome.org/gene/479434:STHE_RS07895 ^@ http://purl.uniprot.org/uniprot/D1C431 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS04775 ^@ http://purl.uniprot.org/uniprot/D1C2C1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS12640 ^@ http://purl.uniprot.org/uniprot/D1CAZ3 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/479434:STHE_RS17570 ^@ http://purl.uniprot.org/uniprot/D1CAS5 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/479434:STHE_RS06725 ^@ http://purl.uniprot.org/uniprot/D1C3F0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08620 ^@ http://purl.uniprot.org/uniprot/D1C4G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/479434:STHE_RS04575 ^@ http://purl.uniprot.org/uniprot/D1C282 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS09830 ^@ http://purl.uniprot.org/uniprot/D1C562 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/479434:STHE_RS02015 ^@ http://purl.uniprot.org/uniprot/D1C7L6 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/479434:STHE_RS04220 ^@ http://purl.uniprot.org/uniprot/D1C215 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/479434:STHE_RS03985 ^@ http://purl.uniprot.org/uniprot/D1C1W7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS05860 ^@ http://purl.uniprot.org/uniprot/D1C2Y5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/479434:STHE_RS17210 ^@ http://purl.uniprot.org/uniprot/D1CAK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS01290 ^@ http://purl.uniprot.org/uniprot/D1C6T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS07190 ^@ http://purl.uniprot.org/uniprot/D1C3P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/479434:STHE_RS09695 ^@ http://purl.uniprot.org/uniprot/D1C535 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/479434:STHE_RS08710 ^@ http://purl.uniprot.org/uniprot/D1C4I7 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/479434:STHE_RS15625 ^@ http://purl.uniprot.org/uniprot/D1C9N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06065 ^@ http://purl.uniprot.org/uniprot/D1C326 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/479434:STHE_RS07755 ^@ http://purl.uniprot.org/uniprot/D1C406 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS11195 ^@ http://purl.uniprot.org/uniprot/D1C6M3 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/479434:STHE_RS03840 ^@ http://purl.uniprot.org/uniprot/D1C1U0 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/479434:STHE_RS07575 ^@ http://purl.uniprot.org/uniprot/D1C3X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08160 ^@ http://purl.uniprot.org/uniprot/D1C478 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/479434:STHE_RS05225 ^@ http://purl.uniprot.org/uniprot/D1C2L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS01875 ^@ http://purl.uniprot.org/uniprot/D1C7I8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/479434:STHE_RS10060 ^@ http://purl.uniprot.org/uniprot/D1C5A8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS07720 ^@ http://purl.uniprot.org/uniprot/D1C3Z9 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/479434:STHE_RS09340 ^@ http://purl.uniprot.org/uniprot/D1C4W4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06470 ^@ http://purl.uniprot.org/uniprot/D1C3A3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/479434:STHE_RS06565 ^@ http://purl.uniprot.org/uniprot/D1C3C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS06265 ^@ http://purl.uniprot.org/uniprot/D1C366 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/479434:STHE_RS05260 ^@ http://purl.uniprot.org/uniprot/D1C2L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/479434:STHE_RS11105 ^@ http://purl.uniprot.org/uniprot/D1C6K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03090 ^@ http://purl.uniprot.org/uniprot/D1C1E3 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/479434:STHE_RS12150 ^@ http://purl.uniprot.org/uniprot/D1C7W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06475 ^@ http://purl.uniprot.org/uniprot/D1C3A4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/479434:STHE_RS12255 ^@ http://purl.uniprot.org/uniprot/D1C7Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/479434:STHE_RS06220 ^@ http://purl.uniprot.org/uniprot/D1C357 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/479434:STHE_RS04375 ^@ http://purl.uniprot.org/uniprot/D1C245 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/479434:STHE_RS17495 ^@ http://purl.uniprot.org/uniprot/D1CAR0 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/479434:STHE_RS11540 ^@ http://purl.uniprot.org/uniprot/D1C775 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS12160 ^@ http://purl.uniprot.org/uniprot/D1C7X0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/479434:STHE_RS08185 ^@ http://purl.uniprot.org/uniprot/D1C481 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/479434:STHE_RS16210 ^@ http://purl.uniprot.org/uniprot/D1C9Z9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/479434:STHE_RS09320 ^@ http://purl.uniprot.org/uniprot/D1C4W0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS00815 ^@ http://purl.uniprot.org/uniprot/D1C667 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/479434:STHE_RS13560 ^@ http://purl.uniprot.org/uniprot/D1C8H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS04795 ^@ http://purl.uniprot.org/uniprot/D1C2C5 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/479434:STHE_RS05880 ^@ http://purl.uniprot.org/uniprot/D1C2Y9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/479434:STHE_RS07775 ^@ http://purl.uniprot.org/uniprot/D1C410 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/479434:STHE_RS08660 ^@ http://purl.uniprot.org/uniprot/D1C4H7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/479434:STHE_RS17565 ^@ http://purl.uniprot.org/uniprot/D1CAS4 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS14370 ^@ http://purl.uniprot.org/uniprot/D1C8Y7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/479434:STHE_RS05290 ^@ http://purl.uniprot.org/uniprot/D1C2M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/479434:STHE_RS01595 ^@ http://purl.uniprot.org/uniprot/D1C704 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/479434:STHE_RS09860 ^@ http://purl.uniprot.org/uniprot/D1C568 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/479434:STHE_RS11390 ^@ http://purl.uniprot.org/uniprot/D1C6R4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/479434:STHE_RS05300 ^@ http://purl.uniprot.org/uniprot/D1C2M7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/479434:STHE_RS16790 ^@ http://purl.uniprot.org/uniprot/D1CAC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS17460 ^@ http://purl.uniprot.org/uniprot/D1CAQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14645 ^@ http://purl.uniprot.org/uniprot/D1C936 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/479434:STHE_RS12310 ^@ http://purl.uniprot.org/uniprot/D1C802 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/479434:STHE_RS02295 ^@ http://purl.uniprot.org/uniprot/D1C7S2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/479434:STHE_RS13405 ^@ http://purl.uniprot.org/uniprot/D1C8E7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS00920 ^@ http://purl.uniprot.org/uniprot/D1C688 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/479434:STHE_RS05245 ^@ http://purl.uniprot.org/uniprot/D1C2L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS06500 ^@ http://purl.uniprot.org/uniprot/D1C3A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/479434:STHE_RS09550 ^@ http://purl.uniprot.org/uniprot/D1C506 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/479434:STHE_RS05900 ^@ http://purl.uniprot.org/uniprot/D1C2Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02770 ^@ http://purl.uniprot.org/uniprot/D1C179 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/479434:STHE_RS12015 ^@ http://purl.uniprot.org/uniprot/D1C7G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04465 ^@ http://purl.uniprot.org/uniprot/D1C261 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/479434:STHE_RS07870 ^@ http://purl.uniprot.org/uniprot/D1C426 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS12505 ^@ http://purl.uniprot.org/uniprot/D1CAW6 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/479434:STHE_RS00750 ^@ http://purl.uniprot.org/uniprot/D1C654 ^@ Similarity|||Subunit ^@ Belongs to the multicopper oxidase family.|||Homotrimer. http://togogenome.org/gene/479434:STHE_RS09295 ^@ http://purl.uniprot.org/uniprot/D1C4V5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS13240 ^@ http://purl.uniprot.org/uniprot/D1C8B4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/479434:STHE_RS08725 ^@ http://purl.uniprot.org/uniprot/D1C4J0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/479434:STHE_RS10870 ^@ http://purl.uniprot.org/uniprot/D1C6G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/479434:STHE_RS11505 ^@ http://purl.uniprot.org/uniprot/D1C768 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/479434:STHE_RS03895 ^@ http://purl.uniprot.org/uniprot/D1C1V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS00365 ^@ http://purl.uniprot.org/uniprot/D1C5J8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/479434:STHE_RS03175 ^@ http://purl.uniprot.org/uniprot/D1C1G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06490 ^@ http://purl.uniprot.org/uniprot/D1C3A7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/479434:STHE_RS03395 ^@ http://purl.uniprot.org/uniprot/D1C1K4 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/479434:STHE_RS10415 ^@ http://purl.uniprot.org/uniprot/D1C5U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09965 ^@ http://purl.uniprot.org/uniprot/D1C589 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/479434:STHE_RS06480 ^@ http://purl.uniprot.org/uniprot/D1C3A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/479434:STHE_RS00185 ^@ http://purl.uniprot.org/uniprot/D1C5G1 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/479434:STHE_RS02275 ^@ http://purl.uniprot.org/uniprot/D1C7R8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/479434:STHE_RS10130 ^@ http://purl.uniprot.org/uniprot/D1C5C3 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/479434:STHE_RS07380 ^@ http://purl.uniprot.org/uniprot/D1C3S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05600 ^@ http://purl.uniprot.org/uniprot/D1C2T5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS06805 ^@ http://purl.uniprot.org/uniprot/D1C3G7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/479434:STHE_RS14935 ^@ http://purl.uniprot.org/uniprot/D1C992 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/479434:STHE_RS12250 ^@ http://purl.uniprot.org/uniprot/D1C7Z0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12490 ^@ http://purl.uniprot.org/uniprot/D1CAW2 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/479434:STHE_RS09925 ^@ http://purl.uniprot.org/uniprot/D1C581 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/479434:STHE_RS04345 ^@ http://purl.uniprot.org/uniprot/D1C239 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS16585 ^@ http://purl.uniprot.org/uniprot/D1CA77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05360 ^@ http://purl.uniprot.org/uniprot/D1C2N9 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/479434:STHE_RS07810 ^@ http://purl.uniprot.org/uniprot/D1C417 ^@ Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS08270 ^@ http://purl.uniprot.org/uniprot/D1C498 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05145 ^@ http://purl.uniprot.org/uniprot/D1C2J6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS15610 ^@ http://purl.uniprot.org/uniprot/D1C9M8 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/479434:STHE_RS05840 ^@ http://purl.uniprot.org/uniprot/D1C2Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS01775 ^@ http://purl.uniprot.org/uniprot/D1C740 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/479434:STHE_RS01615 ^@ http://purl.uniprot.org/uniprot/D1C708 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/479434:STHE_RS09785 ^@ http://purl.uniprot.org/uniprot/D1C553 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/479434:STHE_RS08740 ^@ http://purl.uniprot.org/uniprot/D1C4J3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/479434:STHE_RS00715 ^@ http://purl.uniprot.org/uniprot/D1C647 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/479434:STHE_RS05035 ^@ http://purl.uniprot.org/uniprot/D1C2H2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS09490 ^@ http://purl.uniprot.org/uniprot/D1C4Z4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/479434:STHE_RS12020 ^@ http://purl.uniprot.org/uniprot/D1C7G8 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/479434:STHE_RS12065 ^@ http://purl.uniprot.org/uniprot/D1C7H6 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/479434:STHE_RS05040 ^@ http://purl.uniprot.org/uniprot/D1C2H3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/479434:STHE_RS09460 ^@ http://purl.uniprot.org/uniprot/D1C4Y8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/479434:STHE_RS05155 ^@ http://purl.uniprot.org/uniprot/D1C2J8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/479434:STHE_RS10625 ^@ http://purl.uniprot.org/uniprot/D1C5Y5 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/479434:STHE_RS13635 ^@ http://purl.uniprot.org/uniprot/D1C8J2 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/479434:STHE_RS00860 ^@ http://purl.uniprot.org/uniprot/D1C676 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS04800 ^@ http://purl.uniprot.org/uniprot/D1C2C6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/479434:STHE_RS02780 ^@ http://purl.uniprot.org/uniprot/D1C181 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/479434:STHE_RS05250 ^@ http://purl.uniprot.org/uniprot/D1C2L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/479434:STHE_RS08395 ^@ http://purl.uniprot.org/uniprot/D1C4C4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/479434:STHE_RS02260 ^@ http://purl.uniprot.org/uniprot/D1C7R5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS07215 ^@ http://purl.uniprot.org/uniprot/D1C3P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/479434:STHE_RS11000 ^@ http://purl.uniprot.org/uniprot/D1C6I6 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/479434:STHE_RS04700 ^@ http://purl.uniprot.org/uniprot/D1C2A6 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS11400 ^@ http://purl.uniprot.org/uniprot/D1C6R7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02010 ^@ http://purl.uniprot.org/uniprot/D1C7L5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS00280 ^@ http://purl.uniprot.org/uniprot/D1C5I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS03615 ^@ http://purl.uniprot.org/uniprot/D1C1P8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/479434:STHE_RS15595 ^@ http://purl.uniprot.org/uniprot/D1C9M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/479434:STHE_RS12540 ^@ http://purl.uniprot.org/uniprot/D1CAX3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/479434:STHE_RS07910 ^@ http://purl.uniprot.org/uniprot/D1C434 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS01770 ^@ http://purl.uniprot.org/uniprot/D1C739 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/479434:STHE_RS07750 ^@ http://purl.uniprot.org/uniprot/D1C405 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS01530 ^@ http://purl.uniprot.org/uniprot/D1C6Z1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/479434:STHE_RS02690 ^@ http://purl.uniprot.org/uniprot/D1C163 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/479434:STHE_RS06455 ^@ http://purl.uniprot.org/uniprot/D1C3A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02270 ^@ http://purl.uniprot.org/uniprot/D1C7R7 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/479434:STHE_RS03950 ^@ http://purl.uniprot.org/uniprot/D1C1W0 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/479434:STHE_RS01895 ^@ http://purl.uniprot.org/uniprot/D1C7J2 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS12895 ^@ http://purl.uniprot.org/uniprot/D1C848 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS04125 ^@ http://purl.uniprot.org/uniprot/D1C1Z6 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/479434:STHE_RS08505 ^@ http://purl.uniprot.org/uniprot/D1C4E7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/479434:STHE_RS13895 ^@ http://purl.uniprot.org/uniprot/D1C8P3 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/479434:STHE_RS00195 ^@ http://purl.uniprot.org/uniprot/D1C5G3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/479434:STHE_RS03645 ^@ http://purl.uniprot.org/uniprot/D1C1Q4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/479434:STHE_RS15000 ^@ http://purl.uniprot.org/uniprot/D1C9A5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/479434:STHE_RS04740 ^@ http://purl.uniprot.org/uniprot/D1C2B4 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/479434:STHE_RS12005 ^@ http://purl.uniprot.org/uniprot/D1C7G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/479434:STHE_RS06315 ^@ http://purl.uniprot.org/uniprot/D1C376 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/479434:STHE_RS03035 ^@ http://purl.uniprot.org/uniprot/D1C1D2 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/479434:STHE_RS16550 ^@ http://purl.uniprot.org/uniprot/D1CA69 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/479434:STHE_RS11840 ^@ http://purl.uniprot.org/uniprot/D1C7D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09405 ^@ http://purl.uniprot.org/uniprot/D1C4X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS00450 ^@ http://purl.uniprot.org/uniprot/D1C5L5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02805 ^@ http://purl.uniprot.org/uniprot/D1C186 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/479434:STHE_RS09835 ^@ http://purl.uniprot.org/uniprot/D1C563 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/479434:STHE_RS02790 ^@ http://purl.uniprot.org/uniprot/D1C183 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/479434:STHE_RS07620 ^@ http://purl.uniprot.org/uniprot/D1C3X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS09880 ^@ http://purl.uniprot.org/uniprot/D1C572 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/479434:STHE_RS05220 ^@ http://purl.uniprot.org/uniprot/D1C2L1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/479434:STHE_RS09225 ^@ http://purl.uniprot.org/uniprot/D1C4U1 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/479434:STHE_RS14640 ^@ http://purl.uniprot.org/uniprot/D1C935 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS03485 ^@ http://purl.uniprot.org/uniprot/D1C1M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS05315 ^@ http://purl.uniprot.org/uniprot/D1C2N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/479434:STHE_RS07625 ^@ http://purl.uniprot.org/uniprot/D1C3Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS09755 ^@ http://purl.uniprot.org/uniprot/D1C547 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS17490 ^@ http://purl.uniprot.org/uniprot/D1CAQ9 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/479434:STHE_RS16285 ^@ http://purl.uniprot.org/uniprot/D1CA16 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/479434:STHE_RS08320 ^@ http://purl.uniprot.org/uniprot/D1C4A8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/479434:STHE_RS16085 ^@ http://purl.uniprot.org/uniprot/D1C9X4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/479434:STHE_RS08005 ^@ http://purl.uniprot.org/uniprot/D1C449 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/479434:STHE_RS08980 ^@ http://purl.uniprot.org/uniprot/D1C4P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14680 ^@ http://purl.uniprot.org/uniprot/D1C943 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/479434:STHE_RS11100 ^@ http://purl.uniprot.org/uniprot/D1C6K6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the L-aspartate dehydrogenase family.|||Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.|||The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. http://togogenome.org/gene/479434:STHE_RS13440 ^@ http://purl.uniprot.org/uniprot/D1C8F4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03465 ^@ http://purl.uniprot.org/uniprot/D1C1L8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/479434:STHE_RS16430 ^@ http://purl.uniprot.org/uniprot/D1CA46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06740 ^@ http://purl.uniprot.org/uniprot/D1C3F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS11945 ^@ http://purl.uniprot.org/uniprot/D1C7F3 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/479434:STHE_RS10670 ^@ http://purl.uniprot.org/uniprot/D1C5Z5 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/479434:STHE_RS02340 ^@ http://purl.uniprot.org/uniprot/D1C7T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Homodimer.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. http://togogenome.org/gene/479434:STHE_RS15640 ^@ http://purl.uniprot.org/uniprot/D1C9N4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06040 ^@ http://purl.uniprot.org/uniprot/D1C321 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS12365 ^@ http://purl.uniprot.org/uniprot/D1CAT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AmiS/UreI family.|||Membrane http://togogenome.org/gene/479434:STHE_RS09730 ^@ http://purl.uniprot.org/uniprot/D1C542 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/479434:STHE_RS01505 ^@ http://purl.uniprot.org/uniprot/D1C6Y6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS02610 ^@ http://purl.uniprot.org/uniprot/D1C147 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02115 ^@ http://purl.uniprot.org/uniprot/D1C7N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08225 ^@ http://purl.uniprot.org/uniprot/D1C490 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS11960 ^@ http://purl.uniprot.org/uniprot/D1C7F6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/479434:STHE_RS03955 ^@ http://purl.uniprot.org/uniprot/D1C1W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/479434:STHE_RS03505 ^@ http://purl.uniprot.org/uniprot/D1C1M6 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/479434:STHE_RS06460 ^@ http://purl.uniprot.org/uniprot/D1C3A1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS00445 ^@ http://purl.uniprot.org/uniprot/D1C5L4 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/479434:STHE_RS04235 ^@ http://purl.uniprot.org/uniprot/D1C218 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS14535 ^@ http://purl.uniprot.org/uniprot/D1C920 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS07975 ^@ http://purl.uniprot.org/uniprot/D1C446 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/479434:STHE_RS09145 ^@ http://purl.uniprot.org/uniprot/D1C4S5 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/479434:STHE_RS05470 ^@ http://purl.uniprot.org/uniprot/D1C2R1 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family.|||Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/479434:STHE_RS13615 ^@ http://purl.uniprot.org/uniprot/D1C8I8 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/479434:STHE_RS00540 ^@ http://purl.uniprot.org/uniprot/D1C5N3 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/479434:STHE_RS09480 ^@ http://purl.uniprot.org/uniprot/D1C4Z2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS11760 ^@ http://purl.uniprot.org/uniprot/D1C7B9 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/479434:STHE_RS10075 ^@ http://purl.uniprot.org/uniprot/D1C5B1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/479434:STHE_RS17060 ^@ http://purl.uniprot.org/uniprot/D1CAH4 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/479434:STHE_RS00925 ^@ http://purl.uniprot.org/uniprot/D1C689 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08965 ^@ http://purl.uniprot.org/uniprot/D1C4N9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS14525 ^@ http://purl.uniprot.org/uniprot/D1C918 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/479434:STHE_RS08215 ^@ http://purl.uniprot.org/uniprot/D1C488 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/479434:STHE_RS08810 ^@ http://purl.uniprot.org/uniprot/D1C4K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/479434:STHE_RS08310 ^@ http://purl.uniprot.org/uniprot/D1C4A6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS03550 ^@ http://purl.uniprot.org/uniprot/D1C1N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/479434:STHE_RS06025 ^@ http://purl.uniprot.org/uniprot/D1C318 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/479434:STHE_RS01690 ^@ http://purl.uniprot.org/uniprot/D1C723 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/479434:STHE_RS14055 ^@ http://purl.uniprot.org/uniprot/D1C8S6 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/479434:STHE_RS03600 ^@ http://purl.uniprot.org/uniprot/D1C1P5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS10245 ^@ http://purl.uniprot.org/uniprot/D1C5R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/479434:STHE_RS13445 ^@ http://purl.uniprot.org/uniprot/D1C8F5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03755 ^@ http://purl.uniprot.org/uniprot/D1C1S5 ^@ Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. http://togogenome.org/gene/479434:STHE_RS04105 ^@ http://purl.uniprot.org/uniprot/D1C1Z1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS16610 ^@ http://purl.uniprot.org/uniprot/D1CA82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05320 ^@ http://purl.uniprot.org/uniprot/D1C2N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/479434:STHE_RS17280 ^@ http://purl.uniprot.org/uniprot/D1CAL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05445 ^@ http://purl.uniprot.org/uniprot/D1C2Q6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/479434:STHE_RS05200 ^@ http://purl.uniprot.org/uniprot/D1C2K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/479434:STHE_RS00330 ^@ http://purl.uniprot.org/uniprot/D1C5J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS16325 ^@ http://purl.uniprot.org/uniprot/D1CA24 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/479434:STHE_RS03920 ^@ http://purl.uniprot.org/uniprot/D1C1V4 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/479434:STHE_RS07180 ^@ http://purl.uniprot.org/uniprot/D1C3N8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/479434:STHE_RS00675 ^@ http://purl.uniprot.org/uniprot/D1C639 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/479434:STHE_RS12840 ^@ http://purl.uniprot.org/uniprot/D1C837 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/479434:STHE_RS05305 ^@ http://purl.uniprot.org/uniprot/D1C2M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/479434:STHE_RS17585 ^@ http://purl.uniprot.org/uniprot/D1CAS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS17735 ^@ http://purl.uniprot.org/uniprot/D1C1A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/479434:STHE_RS12200 ^@ http://purl.uniprot.org/uniprot/D1C7X9 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS05870 ^@ http://purl.uniprot.org/uniprot/D1C2Y7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/479434:STHE_RS01750 ^@ http://purl.uniprot.org/uniprot/D1C735 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/479434:STHE_RS05295 ^@ http://purl.uniprot.org/uniprot/D1C2M6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/479434:STHE_RS16145 ^@ http://purl.uniprot.org/uniprot/D1C9Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05345 ^@ http://purl.uniprot.org/uniprot/D1C2N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/479434:STHE_RS01255 ^@ http://purl.uniprot.org/uniprot/D1C6T2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/479434:STHE_RS06060 ^@ http://purl.uniprot.org/uniprot/D1C325 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/479434:STHE_RS07375 ^@ http://purl.uniprot.org/uniprot/D1C3S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15465 ^@ http://purl.uniprot.org/uniprot/D1C9J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03370 ^@ http://purl.uniprot.org/uniprot/D1C1J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS09500 ^@ http://purl.uniprot.org/uniprot/D1C4Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02700 ^@ http://purl.uniprot.org/uniprot/D1C165 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/479434:STHE_RS07300 ^@ http://purl.uniprot.org/uniprot/D1C3R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/479434:STHE_RS03510 ^@ http://purl.uniprot.org/uniprot/D1C1M7 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/479434:STHE_RS10965 ^@ http://purl.uniprot.org/uniprot/D1C6I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS06410 ^@ http://purl.uniprot.org/uniprot/D1C393 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/479434:STHE_RS08130 ^@ http://purl.uniprot.org/uniprot/D1C473 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/479434:STHE_RS16470 ^@ http://purl.uniprot.org/uniprot/D1CA53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/479434:STHE_RS15605 ^@ http://purl.uniprot.org/uniprot/D1C9M7 ^@ Function ^@ Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. http://togogenome.org/gene/479434:STHE_RS09195 ^@ http://purl.uniprot.org/uniprot/D1C4T5 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/479434:STHE_RS12400 ^@ http://purl.uniprot.org/uniprot/D1CAU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/479434:STHE_RS04145 ^@ http://purl.uniprot.org/uniprot/D1C200 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/479434:STHE_RS11060 ^@ http://purl.uniprot.org/uniprot/D1C6J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15785 ^@ http://purl.uniprot.org/uniprot/D1C9R4 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/479434:STHE_RS11485 ^@ http://purl.uniprot.org/uniprot/D1C764 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/479434:STHE_RS00140 ^@ http://purl.uniprot.org/uniprot/D1C5F1 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/479434:STHE_RS10600 ^@ http://purl.uniprot.org/uniprot/D1C5Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/479434:STHE_RS17095 ^@ http://purl.uniprot.org/uniprot/D1CAI0 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/479434:STHE_RS10140 ^@ http://purl.uniprot.org/uniprot/D1C5P0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/479434:STHE_RS01455 ^@ http://purl.uniprot.org/uniprot/D1C6X6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS08530 ^@ http://purl.uniprot.org/uniprot/D1C4F2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/479434:STHE_RS00200 ^@ http://purl.uniprot.org/uniprot/D1C5G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS06840 ^@ http://purl.uniprot.org/uniprot/D1C3H2 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/479434:STHE_RS05100 ^@ http://purl.uniprot.org/uniprot/D1C2I6 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/479434:STHE_RS05255 ^@ http://purl.uniprot.org/uniprot/D1C2L8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/479434:STHE_RS01265 ^@ http://purl.uniprot.org/uniprot/D1C6T4 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/479434:STHE_RS01735 ^@ http://purl.uniprot.org/uniprot/D1C732 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/479434:STHE_RS15495 ^@ http://purl.uniprot.org/uniprot/D1C9K5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS06415 ^@ http://purl.uniprot.org/uniprot/D1C394 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/479434:STHE_RS17760 ^@ http://purl.uniprot.org/uniprot/D1C1N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06530 ^@ http://purl.uniprot.org/uniprot/D1C3B5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/479434:STHE_RS12575 ^@ http://purl.uniprot.org/uniprot/D1CAY0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS06215 ^@ http://purl.uniprot.org/uniprot/D1C356 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/479434:STHE_RS02860 ^@ http://purl.uniprot.org/uniprot/D1C198 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/479434:STHE_RS14915 ^@ http://purl.uniprot.org/uniprot/D1C988 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/479434:STHE_RS10300 ^@ http://purl.uniprot.org/uniprot/D1C5S3 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/479434:STHE_RS05095 ^@ http://purl.uniprot.org/uniprot/D1C2I5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/479434:STHE_RS04640 ^@ http://purl.uniprot.org/uniprot/D1C294 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08125 ^@ http://purl.uniprot.org/uniprot/D1C472 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/479434:STHE_RS00795 ^@ http://purl.uniprot.org/uniprot/D1C663 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/479434:STHE_RS12730 ^@ http://purl.uniprot.org/uniprot/D1C815 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/479434:STHE_RS09735 ^@ http://purl.uniprot.org/uniprot/D1C543 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/479434:STHE_RS04315 ^@ http://purl.uniprot.org/uniprot/D1C233 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS04495 ^@ http://purl.uniprot.org/uniprot/D1C266 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12500 ^@ http://purl.uniprot.org/uniprot/D1CAW5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/479434:STHE_RS05810 ^@ http://purl.uniprot.org/uniprot/D1C2X5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09820 ^@ http://purl.uniprot.org/uniprot/D1C560 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/479434:STHE_RS17660 ^@ http://purl.uniprot.org/uniprot/D1C6S2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/479434:STHE_RS14270 ^@ http://purl.uniprot.org/uniprot/D1C8W7 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/479434:STHE_RS09420 ^@ http://purl.uniprot.org/uniprot/D1C4Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/479434:STHE_RS09150 ^@ http://purl.uniprot.org/uniprot/D1C4S6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS01010 ^@ http://purl.uniprot.org/uniprot/D1C6A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS05820 ^@ http://purl.uniprot.org/uniprot/D1C2X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS02870 ^@ http://purl.uniprot.org/uniprot/D1C1A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/479434:STHE_RS15415 ^@ http://purl.uniprot.org/uniprot/D1C9I8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS15570 ^@ http://purl.uniprot.org/uniprot/D1C9M0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15950 ^@ http://purl.uniprot.org/uniprot/D1C9U6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05815 ^@ http://purl.uniprot.org/uniprot/D1C2X6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/479434:STHE_RS11860 ^@ http://purl.uniprot.org/uniprot/D1C7D8 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/479434:STHE_RS15650 ^@ http://purl.uniprot.org/uniprot/D1C9N6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS08525 ^@ http://purl.uniprot.org/uniprot/D1C4F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/479434:STHE_RS05080 ^@ http://purl.uniprot.org/uniprot/D1C2I1 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/479434:STHE_RS10430 ^@ http://purl.uniprot.org/uniprot/D1C5V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/479434:STHE_RS11080 ^@ http://purl.uniprot.org/uniprot/D1C6K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS09565 ^@ http://purl.uniprot.org/uniprot/D1C509 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS11025 ^@ http://purl.uniprot.org/uniprot/D1C6J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08455 ^@ http://purl.uniprot.org/uniprot/D1C4D6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/479434:STHE_RS14985 ^@ http://purl.uniprot.org/uniprot/D1C9A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS06130 ^@ http://purl.uniprot.org/uniprot/D1C339 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS00145 ^@ http://purl.uniprot.org/uniprot/D1C5F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08500 ^@ http://purl.uniprot.org/uniprot/D1C4E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08585 ^@ http://purl.uniprot.org/uniprot/D1C4G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09760 ^@ http://purl.uniprot.org/uniprot/D1C548 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS02045 ^@ http://purl.uniprot.org/uniprot/D1C7M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/479434:STHE_RS14420 ^@ http://purl.uniprot.org/uniprot/D1C8Z7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/479434:STHE_RS17820 ^@ http://purl.uniprot.org/uniprot/D1C299 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/479434:STHE_RS11530 ^@ http://purl.uniprot.org/uniprot/D1C773 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/479434:STHE_RS09105 ^@ http://purl.uniprot.org/uniprot/D1C4R7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS05175 ^@ http://purl.uniprot.org/uniprot/D1C2K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS12920 ^@ http://purl.uniprot.org/uniprot/D1C850 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/479434:STHE_RS03880 ^@ http://purl.uniprot.org/uniprot/D1C1U7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/479434:STHE_RS07235 ^@ http://purl.uniprot.org/uniprot/D1C3P9 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/479434:STHE_RS00700 ^@ http://purl.uniprot.org/uniprot/D1C644 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS11920 ^@ http://purl.uniprot.org/uniprot/D1C7F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS19015 ^@ http://purl.uniprot.org/uniprot/D1C549 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/479434:STHE_RS06300 ^@ http://purl.uniprot.org/uniprot/D1C373 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/479434:STHE_RS15545 ^@ http://purl.uniprot.org/uniprot/D1C9L4 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/479434:STHE_RS01250 ^@ http://purl.uniprot.org/uniprot/D1C6T1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/479434:STHE_RS00395 ^@ http://purl.uniprot.org/uniprot/D1C5K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07640 ^@ http://purl.uniprot.org/uniprot/D1C3Y3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS14385 ^@ http://purl.uniprot.org/uniprot/D1C8Z0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04605 ^@ http://purl.uniprot.org/uniprot/D1C288 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/479434:STHE_RS11140 ^@ http://purl.uniprot.org/uniprot/D1C6L4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06250 ^@ http://purl.uniprot.org/uniprot/D1C363 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS14665 ^@ http://purl.uniprot.org/uniprot/D1C940 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05990 ^@ http://purl.uniprot.org/uniprot/D1C311 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS02855 ^@ http://purl.uniprot.org/uniprot/D1C197 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/479434:STHE_RS07675 ^@ http://purl.uniprot.org/uniprot/D1C3Z0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/479434:STHE_RS16330 ^@ http://purl.uniprot.org/uniprot/D1CA25 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS01120 ^@ http://purl.uniprot.org/uniprot/D1C6C8 ^@ Similarity ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily. http://togogenome.org/gene/479434:STHE_RS14705 ^@ http://purl.uniprot.org/uniprot/D1C948 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS15110 ^@ http://purl.uniprot.org/uniprot/D1C9C7 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/479434:STHE_RS09600 ^@ http://purl.uniprot.org/uniprot/D1C516 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/479434:STHE_RS04695 ^@ http://purl.uniprot.org/uniprot/D1C2A5 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/479434:STHE_RS05935 ^@ http://purl.uniprot.org/uniprot/D1C300 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS04365 ^@ http://purl.uniprot.org/uniprot/D1C243 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02060 ^@ http://purl.uniprot.org/uniprot/D1C7M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS11045 ^@ http://purl.uniprot.org/uniprot/D1C6J5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/479434:STHE_RS05280 ^@ http://purl.uniprot.org/uniprot/D1C2M3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS09380 ^@ http://purl.uniprot.org/uniprot/D1C4X2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/479434:STHE_RS08460 ^@ http://purl.uniprot.org/uniprot/D1C4D7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/479434:STHE_RS06365 ^@ http://purl.uniprot.org/uniprot/D1C384 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/479434:STHE_RS08900 ^@ http://purl.uniprot.org/uniprot/D1C4M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS14310 ^@ http://purl.uniprot.org/uniprot/D1C8X5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS12295 ^@ http://purl.uniprot.org/uniprot/D1C7Z9 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/479434:STHE_RS05015 ^@ http://purl.uniprot.org/uniprot/D1C2G8 ^@ Cofactor ^@ The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/479434:STHE_RS12270 ^@ http://purl.uniprot.org/uniprot/D1C7Z4 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/479434:STHE_RS08155 ^@ http://purl.uniprot.org/uniprot/D1C477 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/479434:STHE_RS12215 ^@ http://purl.uniprot.org/uniprot/D1C7Y2 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/479434:STHE_RS12790 ^@ http://purl.uniprot.org/uniprot/D1C827 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS06930 ^@ http://purl.uniprot.org/uniprot/D1C3I9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS13775 ^@ http://purl.uniprot.org/uniprot/D1C8M0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05460 ^@ http://purl.uniprot.org/uniprot/D1C2Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08485 ^@ http://purl.uniprot.org/uniprot/D1C4E3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/479434:STHE_RS04030 ^@ http://purl.uniprot.org/uniprot/D1C1X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS07260 ^@ http://purl.uniprot.org/uniprot/D1C3Q5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS04215 ^@ http://purl.uniprot.org/uniprot/D1C214 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/479434:STHE_RS11905 ^@ http://purl.uniprot.org/uniprot/D1C7E7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS17135 ^@ http://purl.uniprot.org/uniprot/D1CAI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/479434:STHE_RS15045 ^@ http://purl.uniprot.org/uniprot/D1C9B4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/479434:STHE_RS15820 ^@ http://purl.uniprot.org/uniprot/D1C9S0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS09750 ^@ http://purl.uniprot.org/uniprot/D1C546 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/479434:STHE_RS10355 ^@ http://purl.uniprot.org/uniprot/D1C5T5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/479434:STHE_RS13150 ^@ http://purl.uniprot.org/uniprot/D1C895 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/479434:STHE_RS01745 ^@ http://purl.uniprot.org/uniprot/D1C734 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/479434:STHE_RS06770 ^@ http://purl.uniprot.org/uniprot/D1C3G0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/479434:STHE_RS10255 ^@ http://purl.uniprot.org/uniprot/D1C5R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS13340 ^@ http://purl.uniprot.org/uniprot/D1C8D4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS05265 ^@ http://purl.uniprot.org/uniprot/D1C2M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/479434:STHE_RS09395 ^@ http://purl.uniprot.org/uniprot/D1C4X5 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/479434:STHE_RS11645 ^@ http://purl.uniprot.org/uniprot/D1C796 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07805 ^@ http://purl.uniprot.org/uniprot/D1C416 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS08245 ^@ http://purl.uniprot.org/uniprot/D1C494 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/479434:STHE_RS02440 ^@ http://purl.uniprot.org/uniprot/D1C7V2 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/479434:STHE_RS11185 ^@ http://purl.uniprot.org/uniprot/D1C6M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/479434:STHE_RS06085 ^@ http://purl.uniprot.org/uniprot/D1C330 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS09205 ^@ http://purl.uniprot.org/uniprot/D1C4T7 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/479434:STHE_RS06610 ^@ http://purl.uniprot.org/uniprot/D1C3D0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/479434:STHE_RS17780 ^@ http://purl.uniprot.org/uniprot/D1C1S3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/479434:STHE_RS07025 ^@ http://purl.uniprot.org/uniprot/D1C3K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16860 ^@ http://purl.uniprot.org/uniprot/D1CAD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08360 ^@ http://purl.uniprot.org/uniprot/D1C4B6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/479434:STHE_RS02130 ^@ http://purl.uniprot.org/uniprot/D1C7N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS03805 ^@ http://purl.uniprot.org/uniprot/D1C1T4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/479434:STHE_RS15845 ^@ http://purl.uniprot.org/uniprot/D1C9S5 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/479434:STHE_RS14715 ^@ http://purl.uniprot.org/uniprot/D1C950 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/479434:STHE_RS05285 ^@ http://purl.uniprot.org/uniprot/D1C2M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS05235 ^@ http://purl.uniprot.org/uniprot/D1C2L4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS00400 ^@ http://purl.uniprot.org/uniprot/D1C5K4 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/479434:STHE_RS09075 ^@ http://purl.uniprot.org/uniprot/D1C4R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS04780 ^@ http://purl.uniprot.org/uniprot/D1C2C2 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/479434:STHE_RS13980 ^@ http://purl.uniprot.org/uniprot/D1C8R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08070 ^@ http://purl.uniprot.org/uniprot/D1C462 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/479434:STHE_RS13505 ^@ http://purl.uniprot.org/uniprot/D1C8G7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/479434:STHE_RS09475 ^@ http://purl.uniprot.org/uniprot/D1C4Z1 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/479434:STHE_RS13520 ^@ http://purl.uniprot.org/uniprot/D1C8H0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/479434:STHE_RS10500 ^@ http://purl.uniprot.org/uniprot/D1C5W0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS10790 ^@ http://purl.uniprot.org/uniprot/D1C6E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16575 ^@ http://purl.uniprot.org/uniprot/D1CA75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16665 ^@ http://purl.uniprot.org/uniprot/D1CA93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06550 ^@ http://purl.uniprot.org/uniprot/D1C3B9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/479434:STHE_RS10015 ^@ http://purl.uniprot.org/uniprot/D1C5A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/479434:STHE_RS01425 ^@ http://purl.uniprot.org/uniprot/D1C6X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS00320 ^@ http://purl.uniprot.org/uniprot/D1C5I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/479434:STHE_RS17690 ^@ http://purl.uniprot.org/uniprot/D1C7P1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/479434:STHE_RS19020 ^@ http://purl.uniprot.org/uniprot/D1C550 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/479434:STHE_RS01470 ^@ http://purl.uniprot.org/uniprot/D1C6X9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/479434:STHE_RS10125 ^@ http://purl.uniprot.org/uniprot/D1C5C2 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/479434:STHE_RS12595 ^@ http://purl.uniprot.org/uniprot/D1CAY4 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/479434:STHE_RS06745 ^@ http://purl.uniprot.org/uniprot/D1C3F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15220 ^@ http://purl.uniprot.org/uniprot/D1C9E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS17350 ^@ http://purl.uniprot.org/uniprot/D1CAN1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS01700 ^@ http://purl.uniprot.org/uniprot/D1C725 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/479434:STHE_RS11165 ^@ http://purl.uniprot.org/uniprot/D1C6L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09415 ^@ http://purl.uniprot.org/uniprot/D1C4X9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/479434:STHE_RS13020 ^@ http://purl.uniprot.org/uniprot/D1C869 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS08815 ^@ http://purl.uniprot.org/uniprot/D1C4K7 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06030 ^@ http://purl.uniprot.org/uniprot/D1C319 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS16955 ^@ http://purl.uniprot.org/uniprot/D1CAF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS03215 ^@ http://purl.uniprot.org/uniprot/D1C1H0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/479434:STHE_RS07135 ^@ http://purl.uniprot.org/uniprot/D1C3M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/479434:STHE_RS07370 ^@ http://purl.uniprot.org/uniprot/D1C3S7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/479434:STHE_RS00455 ^@ http://purl.uniprot.org/uniprot/D1C5L6 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/479434:STHE_RS13970 ^@ http://purl.uniprot.org/uniprot/D1C8Q8 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/479434:STHE_RS08950 ^@ http://purl.uniprot.org/uniprot/D1C4N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04760 ^@ http://purl.uniprot.org/uniprot/D1C2B8 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/479434:STHE_RS14480 ^@ http://purl.uniprot.org/uniprot/D1C909 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/479434:STHE_RS08800 ^@ http://purl.uniprot.org/uniprot/D1C4K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/479434:STHE_RS05750 ^@ http://purl.uniprot.org/uniprot/D1C2W5 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/479434:STHE_RS09100 ^@ http://purl.uniprot.org/uniprot/D1C4R6 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/479434:STHE_RS00180 ^@ http://purl.uniprot.org/uniprot/D1C5G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS06995 ^@ http://purl.uniprot.org/uniprot/D1C3K1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/479434:STHE_RS01685 ^@ http://purl.uniprot.org/uniprot/D1C722 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/479434:STHE_RS15430 ^@ http://purl.uniprot.org/uniprot/D1C9J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/479434:STHE_RS07030 ^@ http://purl.uniprot.org/uniprot/D1C3K8 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/479434:STHE_RS15180 ^@ http://purl.uniprot.org/uniprot/D1C9E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15485 ^@ http://purl.uniprot.org/uniprot/D1C9K2 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/479434:STHE_RS03350 ^@ http://purl.uniprot.org/uniprot/D1C1J5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/479434:STHE_RS09505 ^@ http://purl.uniprot.org/uniprot/D1C4Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS16640 ^@ http://purl.uniprot.org/uniprot/D1CA88 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/479434:STHE_RS06280 ^@ http://purl.uniprot.org/uniprot/D1C369 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/479434:STHE_RS08690 ^@ http://purl.uniprot.org/uniprot/D1C4I3 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/479434:STHE_RS11935 ^@ http://purl.uniprot.org/uniprot/D1C7F1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/479434:STHE_RS10335 ^@ http://purl.uniprot.org/uniprot/D1C5T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06655 ^@ http://purl.uniprot.org/uniprot/D1C3D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/479434:STHE_RS13755 ^@ http://purl.uniprot.org/uniprot/D1C8L6 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/479434:STHE_RS01760 ^@ http://purl.uniprot.org/uniprot/D1C737 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS02785 ^@ http://purl.uniprot.org/uniprot/D1C182 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/479434:STHE_RS01285 ^@ http://purl.uniprot.org/uniprot/D1C6T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS13260 ^@ http://purl.uniprot.org/uniprot/D1C8B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS02850 ^@ http://purl.uniprot.org/uniprot/D1C196 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/479434:STHE_RS14345 ^@ http://purl.uniprot.org/uniprot/D1C8Y2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/479434:STHE_RS06425 ^@ http://purl.uniprot.org/uniprot/D1C396 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS17840 ^@ http://purl.uniprot.org/uniprot/D1C2W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05240 ^@ http://purl.uniprot.org/uniprot/D1C2L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/479434:STHE_RS07205 ^@ http://purl.uniprot.org/uniprot/D1C3P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/479434:STHE_RS01800 ^@ http://purl.uniprot.org/uniprot/D1C745 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/479434:STHE_RS13470 ^@ http://purl.uniprot.org/uniprot/D1C8G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Mitochondrion http://togogenome.org/gene/479434:STHE_RS00055 ^@ http://purl.uniprot.org/uniprot/D1C5D4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/479434:STHE_RS17110 ^@ http://purl.uniprot.org/uniprot/D1CAI3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/479434:STHE_RS05335 ^@ http://purl.uniprot.org/uniprot/D1C2N4 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/479434:STHE_RS15375 ^@ http://purl.uniprot.org/uniprot/D1C9I1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/479434:STHE_RS02035 ^@ http://purl.uniprot.org/uniprot/D1C7M0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/479434:STHE_RS16645 ^@ http://purl.uniprot.org/uniprot/D1CA89 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS09825 ^@ http://purl.uniprot.org/uniprot/D1C561 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/479434:STHE_RS15120 ^@ http://purl.uniprot.org/uniprot/D1C9C9 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS08385 ^@ http://purl.uniprot.org/uniprot/D1C4C1 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS13015 ^@ http://purl.uniprot.org/uniprot/D1C868 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/479434:STHE_RS14965 ^@ http://purl.uniprot.org/uniprot/D1C998 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/479434:STHE_RS06510 ^@ http://purl.uniprot.org/uniprot/D1C3B1 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/479434:STHE_RS03230 ^@ http://purl.uniprot.org/uniprot/D1C1H3 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/479434:STHE_RS11855 ^@ http://purl.uniprot.org/uniprot/D1C7D7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/479434:STHE_RS01075 ^@ http://purl.uniprot.org/uniprot/D1C6B9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS04175 ^@ http://purl.uniprot.org/uniprot/D1C206 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/479434:STHE_RS09085 ^@ http://purl.uniprot.org/uniprot/D1C4R3 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/479434:STHE_RS06780 ^@ http://purl.uniprot.org/uniprot/D1C3G2 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/479434:STHE_RS07655 ^@ http://purl.uniprot.org/uniprot/D1C3Y6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS05310 ^@ http://purl.uniprot.org/uniprot/D1C2M9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/479434:STHE_RS14670 ^@ http://purl.uniprot.org/uniprot/D1C941 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS14020 ^@ http://purl.uniprot.org/uniprot/D1C8R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS13715 ^@ http://purl.uniprot.org/uniprot/D1C8K8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12495 ^@ http://purl.uniprot.org/uniprot/D1CAW4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/479434:STHE_RS05215 ^@ http://purl.uniprot.org/uniprot/D1C2L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/479434:STHE_RS09020 ^@ http://purl.uniprot.org/uniprot/D1C4Q0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/479434:STHE_RS08635 ^@ http://purl.uniprot.org/uniprot/D1C4H2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/479434:STHE_RS00070 ^@ http://purl.uniprot.org/uniprot/D1C5D7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS11535 ^@ http://purl.uniprot.org/uniprot/D1C774 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/479434:STHE_RS14555 ^@ http://purl.uniprot.org/uniprot/D1C924 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS11545 ^@ http://purl.uniprot.org/uniprot/D1C776 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/479434:STHE_RS11875 ^@ http://purl.uniprot.org/uniprot/D1C7E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/479434:STHE_RS11040 ^@ http://purl.uniprot.org/uniprot/D1C6J4 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/479434:STHE_RS06465 ^@ http://purl.uniprot.org/uniprot/D1C3A2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS15410 ^@ http://purl.uniprot.org/uniprot/D1C9I7 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/479434:STHE_RS07110 ^@ http://purl.uniprot.org/uniprot/D1C3M4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/479434:STHE_RS02380 ^@ http://purl.uniprot.org/uniprot/D1C7T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14125 ^@ http://purl.uniprot.org/uniprot/D1C8U0 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/479434:STHE_RS08135 ^@ http://purl.uniprot.org/uniprot/D1C474 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/479434:STHE_RS04730 ^@ http://purl.uniprot.org/uniprot/D1C2B2 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/479434:STHE_RS10205 ^@ http://purl.uniprot.org/uniprot/D1C5Q4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS01035 ^@ http://purl.uniprot.org/uniprot/D1C6B1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS13850 ^@ http://purl.uniprot.org/uniprot/D1C8N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08955 ^@ http://purl.uniprot.org/uniprot/D1C4N7 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/479434:STHE_RS05275 ^@ http://purl.uniprot.org/uniprot/D1C2M2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/479434:STHE_RS08175 ^@ http://purl.uniprot.org/uniprot/D1C479 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/479434:STHE_RS00425 ^@ http://purl.uniprot.org/uniprot/D1C5L0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/479434:STHE_RS07325 ^@ http://purl.uniprot.org/uniprot/D1C3R8 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS16985 ^@ http://purl.uniprot.org/uniprot/D1CAF9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/479434:STHE_RS09545 ^@ http://purl.uniprot.org/uniprot/D1C505 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/479434:STHE_RS11440 ^@ http://purl.uniprot.org/uniprot/D1C754 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS09590 ^@ http://purl.uniprot.org/uniprot/D1C514 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/479434:STHE_RS04515 ^@ http://purl.uniprot.org/uniprot/D1C270 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS02740 ^@ http://purl.uniprot.org/uniprot/D1C173 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/479434:STHE_RS13485 ^@ http://purl.uniprot.org/uniprot/D1C8G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS00035 ^@ http://purl.uniprot.org/uniprot/D1C5D0 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/479434:STHE_RS08890 ^@ http://purl.uniprot.org/uniprot/D1C4M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/479434:STHE_RS17550 ^@ http://purl.uniprot.org/uniprot/D1CAS1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS14440 ^@ http://purl.uniprot.org/uniprot/D1C901 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15770 ^@ http://purl.uniprot.org/uniprot/D1C9R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02730 ^@ http://purl.uniprot.org/uniprot/D1C171 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/479434:STHE_RS08550 ^@ http://purl.uniprot.org/uniprot/D1C4F6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS08325 ^@ http://purl.uniprot.org/uniprot/D1C4A9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/479434:STHE_RS03800 ^@ http://purl.uniprot.org/uniprot/D1C1T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/479434:STHE_RS06070 ^@ http://purl.uniprot.org/uniprot/D1C327 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/479434:STHE_RS05915 ^@ http://purl.uniprot.org/uniprot/D1C2Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/479434:STHE_RS10135 ^@ http://purl.uniprot.org/uniprot/D1C5N9 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/479434:STHE_RS02520 ^@ http://purl.uniprot.org/uniprot/D1C135 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/479434:STHE_RS09110 ^@ http://purl.uniprot.org/uniprot/D1C4R8 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/479434:STHE_RS13820 ^@ http://purl.uniprot.org/uniprot/D1C8M9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/479434:STHE_RS16555 ^@ http://purl.uniprot.org/uniprot/D1CA70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12965 ^@ http://purl.uniprot.org/uniprot/D1C858 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/479434:STHE_RS17730 ^@ http://purl.uniprot.org/uniprot/D1C185 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/479434:STHE_RS07610 ^@ http://purl.uniprot.org/uniprot/D1C3X7 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/479434:STHE_RS03650 ^@ http://purl.uniprot.org/uniprot/D1C1Q5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NosZ family.|||Homodimer.|||In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.|||Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.|||Periplasm http://togogenome.org/gene/479434:STHE_RS07175 ^@ http://purl.uniprot.org/uniprot/D1C3N7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS03925 ^@ http://purl.uniprot.org/uniprot/D1C1V5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/479434:STHE_RS04625 ^@ http://purl.uniprot.org/uniprot/D1C292 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/479434:STHE_RS09200 ^@ http://purl.uniprot.org/uniprot/D1C4T6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/479434:STHE_RS11190 ^@ http://purl.uniprot.org/uniprot/D1C6M2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/479434:STHE_RS11870 ^@ http://purl.uniprot.org/uniprot/D1C7E0 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/479434:STHE_RS14940 ^@ http://purl.uniprot.org/uniprot/D1C993 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS02885 ^@ http://purl.uniprot.org/uniprot/D1C1A3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/479434:STHE_RS04135 ^@ http://purl.uniprot.org/uniprot/D1C1Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS03865 ^@ http://purl.uniprot.org/uniprot/D1C1U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/479434:STHE_RS05340 ^@ http://purl.uniprot.org/uniprot/D1C2N5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS03315 ^@ http://purl.uniprot.org/uniprot/D1C1I9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/479434:STHE_RS04120 ^@ http://purl.uniprot.org/uniprot/D1C1Z5 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/479434:STHE_RS16510 ^@ http://purl.uniprot.org/uniprot/D1CA61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS01445 ^@ http://purl.uniprot.org/uniprot/D1C6X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/479434:STHE_RS00385 ^@ http://purl.uniprot.org/uniprot/D1C5K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10650 ^@ http://purl.uniprot.org/uniprot/D1C5Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS06970 ^@ http://purl.uniprot.org/uniprot/D1C3J6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/479434:STHE_RS02330 ^@ http://purl.uniprot.org/uniprot/D1C7S9 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/479434:STHE_RS07940 ^@ http://purl.uniprot.org/uniprot/D1C439 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/479434:STHE_RS10805 ^@ http://purl.uniprot.org/uniprot/D1C6E9 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/479434:STHE_RS16335 ^@ http://purl.uniprot.org/uniprot/D1CA26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04025 ^@ http://purl.uniprot.org/uniprot/D1C1X5 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/479434:STHE_RS00205 ^@ http://purl.uniprot.org/uniprot/D1C5G5 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/479434:STHE_RS05790 ^@ http://purl.uniprot.org/uniprot/D1C2X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05180 ^@ http://purl.uniprot.org/uniprot/D1C2K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/479434:STHE_RS08010 ^@ http://purl.uniprot.org/uniprot/D1C450 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/479434:STHE_RS17580 ^@ http://purl.uniprot.org/uniprot/D1CAS7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/479434:STHE_RS15170 ^@ http://purl.uniprot.org/uniprot/D1C9D8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06330 ^@ http://purl.uniprot.org/uniprot/D1C379 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/479434:STHE_RS05395 ^@ http://purl.uniprot.org/uniprot/D1C2P6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS03680 ^@ http://purl.uniprot.org/uniprot/D1C1R0 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/479434:STHE_RS06570 ^@ http://purl.uniprot.org/uniprot/D1C3C3 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/479434:STHE_RS06295 ^@ http://purl.uniprot.org/uniprot/D1C372 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/479434:STHE_RS06640 ^@ http://purl.uniprot.org/uniprot/D1C3D6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/479434:STHE_RS06600 ^@ http://purl.uniprot.org/uniprot/D1C3C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/479434:STHE_RS16020 ^@ http://purl.uniprot.org/uniprot/D1C9W1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/479434:STHE_RS14980 ^@ http://purl.uniprot.org/uniprot/D1C9A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS17635 ^@ http://purl.uniprot.org/uniprot/D1C665 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/479434:STHE_RS16840 ^@ http://purl.uniprot.org/uniprot/D1CAD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15145 ^@ http://purl.uniprot.org/uniprot/D1C9D3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/479434:STHE_RS06785 ^@ http://purl.uniprot.org/uniprot/D1C3G3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/479434:STHE_RS07880 ^@ http://purl.uniprot.org/uniprot/D1C428 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS04915 ^@ http://purl.uniprot.org/uniprot/D1C2E8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/479434:STHE_RS10755 ^@ http://purl.uniprot.org/uniprot/D1C612 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS15765 ^@ http://purl.uniprot.org/uniprot/D1C9R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS02325 ^@ http://purl.uniprot.org/uniprot/D1C7S8 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/479434:STHE_RS12760 ^@ http://purl.uniprot.org/uniprot/D1C821 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/479434:STHE_RS10040 ^@ http://purl.uniprot.org/uniprot/D1C5A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS12735 ^@ http://purl.uniprot.org/uniprot/D1C816 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS08430 ^@ http://purl.uniprot.org/uniprot/D1C4D1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/479434:STHE_RS02315 ^@ http://purl.uniprot.org/uniprot/D1C7S6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/479434:STHE_RS02760 ^@ http://purl.uniprot.org/uniprot/D1C177 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/479434:STHE_RS10170 ^@ http://purl.uniprot.org/uniprot/D1C5P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS06120 ^@ http://purl.uniprot.org/uniprot/D1C337 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/479434:STHE_RS09045 ^@ http://purl.uniprot.org/uniprot/D1C4Q5 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/479434:STHE_RS05195 ^@ http://purl.uniprot.org/uniprot/D1C2K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/479434:STHE_RS05270 ^@ http://purl.uniprot.org/uniprot/D1C2M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/479434:STHE_RS17480 ^@ http://purl.uniprot.org/uniprot/D1CAQ7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/479434:STHE_RS04955 ^@ http://purl.uniprot.org/uniprot/D1C2F6 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/479434:STHE_RS01845 ^@ http://purl.uniprot.org/uniprot/D1C7I2 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/479434:STHE_RS03810 ^@ http://purl.uniprot.org/uniprot/D1C1T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/479434:STHE_RS13390 ^@ http://purl.uniprot.org/uniprot/D1C8E5 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/479434:STHE_RS05230 ^@ http://purl.uniprot.org/uniprot/D1C2L3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/479434:STHE_RS17165 ^@ http://purl.uniprot.org/uniprot/D1CAJ4 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/479434:STHE_RS14145 ^@ http://purl.uniprot.org/uniprot/D1C8U4 ^@ Function ^@ Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/479434:STHE_RS17115 ^@ http://purl.uniprot.org/uniprot/D1CAI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS01410 ^@ http://purl.uniprot.org/uniprot/D1C6W7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07585 ^@ http://purl.uniprot.org/uniprot/D1C3X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS04075 ^@ http://purl.uniprot.org/uniprot/D1C1Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS14970 ^@ http://purl.uniprot.org/uniprot/D1C999 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07815 ^@ http://purl.uniprot.org/uniprot/D1C418 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS12460 ^@ http://purl.uniprot.org/uniprot/D1CAV6 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/479434:STHE_RS03545 ^@ http://purl.uniprot.org/uniprot/D1C1N4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/479434:STHE_RS06735 ^@ http://purl.uniprot.org/uniprot/D1C3F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS10215 ^@ http://purl.uniprot.org/uniprot/D1C5Q6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/479434:STHE_RS11755 ^@ http://purl.uniprot.org/uniprot/D1C7B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS05555 ^@ http://purl.uniprot.org/uniprot/D1C2S7 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS16315 ^@ http://purl.uniprot.org/uniprot/D1CA22 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/479434:STHE_RS09185 ^@ http://purl.uniprot.org/uniprot/D1C4T3 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/479434:STHE_RS03415 ^@ http://purl.uniprot.org/uniprot/D1C1K8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/479434:STHE_RS01555 ^@ http://purl.uniprot.org/uniprot/D1C6Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/479434:STHE_RS10080 ^@ http://purl.uniprot.org/uniprot/D1C5B2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/479434:STHE_RS11110 ^@ http://purl.uniprot.org/uniprot/D1C6K8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/479434:STHE_RS00810 ^@ http://purl.uniprot.org/uniprot/D1C666 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/479434:STHE_RS16815 ^@ http://purl.uniprot.org/uniprot/D1CAC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS14505 ^@ http://purl.uniprot.org/uniprot/D1C914 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS02660 ^@ http://purl.uniprot.org/uniprot/D1C157 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/479434:STHE_RS04090 ^@ http://purl.uniprot.org/uniprot/D1C1Y8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/479434:STHE_RS03670 ^@ http://purl.uniprot.org/uniprot/D1C1Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15330 ^@ http://purl.uniprot.org/uniprot/D1C9H2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/479434:STHE_RS15965 ^@ http://purl.uniprot.org/uniprot/D1C9V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS16635 ^@ http://purl.uniprot.org/uniprot/D1CA87 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/479434:STHE_RS06545 ^@ http://purl.uniprot.org/uniprot/D1C3B8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Nucleus|||Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. http://togogenome.org/gene/479434:STHE_RS08610 ^@ http://purl.uniprot.org/uniprot/D1C4G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS15450 ^@ http://purl.uniprot.org/uniprot/D1C9J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS00725 ^@ http://purl.uniprot.org/uniprot/D1C649 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/479434:STHE_RS12130 ^@ http://purl.uniprot.org/uniprot/D1C7W4 ^@ Cofactor|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/479434:STHE_RS04845 ^@ http://purl.uniprot.org/uniprot/D1C2D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/479434:STHE_RS01030 ^@ http://purl.uniprot.org/uniprot/D1C6B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/479434:STHE_RS16850 ^@ http://purl.uniprot.org/uniprot/D1CAD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/479434:STHE_RS03365 ^@ http://purl.uniprot.org/uniprot/D1C1J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/479434:STHE_RS05115 ^@ http://purl.uniprot.org/uniprot/D1C2I9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/479434:STHE_RS07555 ^@ http://purl.uniprot.org/uniprot/D1C3W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS00870 ^@ http://purl.uniprot.org/uniprot/D1C678 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/479434:STHE_RS07690 ^@ http://purl.uniprot.org/uniprot/D1C3Z3 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/479434:STHE_RS04615 ^@ http://purl.uniprot.org/uniprot/D1C290 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/479434:STHE_RS08400 ^@ http://purl.uniprot.org/uniprot/D1C4C5 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/479434:STHE_RS08180 ^@ http://purl.uniprot.org/uniprot/D1C480 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/479434:STHE_RS13410 ^@ http://purl.uniprot.org/uniprot/D1C8E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/479434:STHE_RS04395 ^@ http://purl.uniprot.org/uniprot/D1C249 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/479434:STHE_RS09440 ^@ http://purl.uniprot.org/uniprot/D1C4Y4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/479434:STHE_RS11135 ^@ http://purl.uniprot.org/uniprot/D1C6L3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/479434:STHE_RS06845 ^@ http://purl.uniprot.org/uniprot/D1C3H3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/479434:STHE_RS13290 ^@ http://purl.uniprot.org/uniprot/D1C8C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/479434:STHE_RS16830 ^@ http://purl.uniprot.org/uniprot/D1CAC9 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/479434:STHE_RS05720 ^@ http://purl.uniprot.org/uniprot/D1C2V9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/479434:STHE_RS02420 ^@ http://purl.uniprot.org/uniprot/D1C7U8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family.