http://togogenome.org/gene/526218:STERM_RS17995 ^@ http://purl.uniprot.org/uniprot/D1ARJ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/526218:STERM_RS17295 ^@ http://purl.uniprot.org/uniprot/D1AQS8 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/526218:STERM_RS07505 ^@ http://purl.uniprot.org/uniprot/D1AI05 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/526218:STERM_RS19065 ^@ http://purl.uniprot.org/uniprot/D1AG52 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/526218:STERM_RS17465 ^@ http://purl.uniprot.org/uniprot/D1AQW1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/526218:STERM_RS11985 ^@ http://purl.uniprot.org/uniprot/D1ALE7 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/526218:STERM_RS21330 ^@ http://purl.uniprot.org/uniprot/D1AMA1 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/526218:STERM_RS20035 ^@ http://purl.uniprot.org/uniprot/D1AGB8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/526218:STERM_RS01905 ^@ http://purl.uniprot.org/uniprot/D1ALZ8 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/526218:STERM_RS11830 ^@ http://purl.uniprot.org/uniprot/D1ALB6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/526218:STERM_RS19820 ^@ http://purl.uniprot.org/uniprot/D1AGV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/526218:STERM_RS00865 ^@ http://purl.uniprot.org/uniprot/D1AJZ8 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/526218:STERM_RS20725 ^@ http://purl.uniprot.org/uniprot/D1AS14 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/526218:STERM_RS06370 ^@ http://purl.uniprot.org/uniprot/D1AHC4 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/526218:STERM_RS09360 ^@ http://purl.uniprot.org/uniprot/D1AJ74 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/526218:STERM_RS17075 ^@ http://purl.uniprot.org/uniprot/D1AQN6 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/526218:STERM_RS15045 ^@ http://purl.uniprot.org/uniprot/D1ANU3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/526218:STERM_RS02640 ^@ http://purl.uniprot.org/uniprot/D1AN34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/526218:STERM_RS15600 ^@ http://purl.uniprot.org/uniprot/D1APH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS10495 ^@ http://purl.uniprot.org/uniprot/D1AK72 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/526218:STERM_RS07255 ^@ http://purl.uniprot.org/uniprot/D1AHV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08110 ^@ http://purl.uniprot.org/uniprot/D1AIC4 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS08235 ^@ http://purl.uniprot.org/uniprot/D1AIE9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/526218:STERM_RS11570 ^@ http://purl.uniprot.org/uniprot/D1AL64 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/526218:STERM_RS11980 ^@ http://purl.uniprot.org/uniprot/D1ALE6 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/526218:STERM_RS08820 ^@ http://purl.uniprot.org/uniprot/D1AIR6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS14515 ^@ http://purl.uniprot.org/uniprot/D1ANJ3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/526218:STERM_RS08370 ^@ http://purl.uniprot.org/uniprot/D1AIH6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/526218:STERM_RS13510 ^@ http://purl.uniprot.org/uniprot/D1AMM0 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS00370 ^@ http://purl.uniprot.org/uniprot/D1AJQ6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS18650 ^@ http://purl.uniprot.org/uniprot/D1ARV9 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/526218:STERM_RS06400 ^@ http://purl.uniprot.org/uniprot/D1AHD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS00895 ^@ http://purl.uniprot.org/uniprot/D1AKP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/526218:STERM_RS00795 ^@ http://purl.uniprot.org/uniprot/D1AJY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/526218:STERM_RS11730 ^@ http://purl.uniprot.org/uniprot/D1AL96 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/526218:STERM_RS18295 ^@ http://purl.uniprot.org/uniprot/D1ARP7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS00470 ^@ http://purl.uniprot.org/uniprot/D1AJS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/526218:STERM_RS09415 ^@ http://purl.uniprot.org/uniprot/D1AJ85 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/526218:STERM_RS01470 ^@ http://purl.uniprot.org/uniprot/D1AL10 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/526218:STERM_RS09070 ^@ http://purl.uniprot.org/uniprot/D1AJ15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS09630 ^@ http://purl.uniprot.org/uniprot/D1AJC7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/526218:STERM_RS20195 ^@ http://purl.uniprot.org/uniprot/D1AGF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/526218:STERM_RS05200 ^@ http://purl.uniprot.org/uniprot/D1AFN7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/526218:STERM_RS10445 ^@ http://purl.uniprot.org/uniprot/D1AK62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS05435 ^@ http://purl.uniprot.org/uniprot/D1AFT4 ^@ Similarity ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/526218:STERM_RS16110 ^@ http://purl.uniprot.org/uniprot/D1APS3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/526218:STERM_RS12880 ^@ http://purl.uniprot.org/uniprot/D1AM94 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/526218:STERM_RS14680 ^@ http://purl.uniprot.org/uniprot/D1ANM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS00260 ^@ http://purl.uniprot.org/uniprot/D1AJN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS13695 ^@ http://purl.uniprot.org/uniprot/D1AMQ2 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/526218:STERM_RS18860 ^@ http://purl.uniprot.org/uniprot/D1AG11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase H family.|||Binds 2 metal ions per subunit. Manganese or magnesium.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. http://togogenome.org/gene/526218:STERM_RS08245 ^@ http://purl.uniprot.org/uniprot/D1AIF1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/526218:STERM_RS09495 ^@ http://purl.uniprot.org/uniprot/D1AJA0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/526218:STERM_RS19620 ^@ http://purl.uniprot.org/uniprot/D1AGR7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/526218:STERM_RS11665 ^@ http://purl.uniprot.org/uniprot/D1AL83 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS01745 ^@ http://purl.uniprot.org/uniprot/D1ALW6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS15685 ^@ http://purl.uniprot.org/uniprot/D1API9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class A bacterial acid phosphatase family.|||Periplasm http://togogenome.org/gene/526218:STERM_RS00630 ^@ http://purl.uniprot.org/uniprot/D1AJV8 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/526218:STERM_RS12875 ^@ http://purl.uniprot.org/uniprot/D1AM93 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/526218:STERM_RS09250 ^@ http://purl.uniprot.org/uniprot/D1AJ52 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/526218:STERM_RS01265 ^@ http://purl.uniprot.org/uniprot/D1AKW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/526218:STERM_RS12500 ^@ http://purl.uniprot.org/uniprot/D1ALQ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS02805 ^@ http://purl.uniprot.org/uniprot/D1ANX1 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/526218:STERM_RS19120 ^@ http://purl.uniprot.org/uniprot/D1AG63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS05335 ^@ http://purl.uniprot.org/uniprot/D1AFR4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/526218:STERM_RS00110 ^@ http://purl.uniprot.org/uniprot/D1AIU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/526218:STERM_RS00095 ^@ http://purl.uniprot.org/uniprot/D1AIU5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS03590 ^@ http://purl.uniprot.org/uniprot/D1AQ25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15825 ^@ http://purl.uniprot.org/uniprot/D1APL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01900 ^@ http://purl.uniprot.org/uniprot/D1ALZ7 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-II family. http://togogenome.org/gene/526218:STERM_RS03780 ^@ http://purl.uniprot.org/uniprot/D1AQ63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/526218:STERM_RS11335 ^@ http://purl.uniprot.org/uniprot/D1AL17 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS13680 ^@ http://purl.uniprot.org/uniprot/D1AMP9 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/526218:STERM_RS09505 ^@ http://purl.uniprot.org/uniprot/D1AJA2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS03755 ^@ http://purl.uniprot.org/uniprot/D1AQ58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/526218:STERM_RS09680 ^@ http://purl.uniprot.org/uniprot/D1AJD6 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/526218:STERM_RS01515 ^@ http://purl.uniprot.org/uniprot/D1ALR8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/526218:STERM_RS02850 ^@ http://purl.uniprot.org/uniprot/D1ANY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS00575 ^@ http://purl.uniprot.org/uniprot/D1AJU7 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/526218:STERM_RS11630 ^@ http://purl.uniprot.org/uniprot/D1AL76 ^@ Function|||Similarity|||Subunit ^@ Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.|||Belongs to the HutP family.|||Homohexamer. http://togogenome.org/gene/526218:STERM_RS10725 ^@ http://purl.uniprot.org/uniprot/D1AKB9 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/526218:STERM_RS13480 ^@ http://purl.uniprot.org/uniprot/D1AML4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/526218:STERM_RS00815 ^@ http://purl.uniprot.org/uniprot/D1AJY8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS04815 ^@ http://purl.uniprot.org/uniprot/D1AFF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS09660 ^@ http://purl.uniprot.org/uniprot/D1AJD2 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/526218:STERM_RS05650 ^@ http://purl.uniprot.org/uniprot/D1AFX7 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/526218:STERM_RS16925 ^@ http://purl.uniprot.org/uniprot/D1AQK7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS17055 ^@ http://purl.uniprot.org/uniprot/D1AQN2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS03730 ^@ http://purl.uniprot.org/uniprot/D1AQ53 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/526218:STERM_RS15035 ^@ http://purl.uniprot.org/uniprot/D1ANU1 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/526218:STERM_RS17015 ^@ http://purl.uniprot.org/uniprot/D1AQM4 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/526218:STERM_RS13045 ^@ http://purl.uniprot.org/uniprot/D1AMC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS00820 ^@ http://purl.uniprot.org/uniprot/D1AJY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS16710 ^@ http://purl.uniprot.org/uniprot/D1AQG3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS02855 ^@ http://purl.uniprot.org/uniprot/D1ANY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/526218:STERM_RS00495 ^@ http://purl.uniprot.org/uniprot/D1AJT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/526218:STERM_RS03870 ^@ http://purl.uniprot.org/uniprot/D1AQ81 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/526218:STERM_RS16390 ^@ http://purl.uniprot.org/uniprot/D1AQA1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/526218:STERM_RS09795 ^@ http://purl.uniprot.org/uniprot/D1AJF9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS17635 ^@ http://purl.uniprot.org/uniprot/D1ARB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell inner membrane|||H(+)-stimulated, divalent metal cation uptake system.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS09865 ^@ http://purl.uniprot.org/uniprot/D1AJH3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/526218:STERM_RS10615 ^@ http://purl.uniprot.org/uniprot/D1AK97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01770 ^@ http://purl.uniprot.org/uniprot/D1ALX1 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/526218:STERM_RS12245 ^@ http://purl.uniprot.org/uniprot/D1ALJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS13810 ^@ http://purl.uniprot.org/uniprot/D1AN45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS14600 ^@ http://purl.uniprot.org/uniprot/D1ANK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease M5 family.|||Cytoplasm|||Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. http://togogenome.org/gene/526218:STERM_RS14500 ^@ http://purl.uniprot.org/uniprot/D1ANJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/526218:STERM_RS10850 ^@ http://purl.uniprot.org/uniprot/D1AKE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS00015 ^@ http://purl.uniprot.org/uniprot/D1AIS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/526218:STERM_RS07510 ^@ http://purl.uniprot.org/uniprot/D1AI06 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/526218:STERM_RS10715 ^@ http://purl.uniprot.org/uniprot/D1AKB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19780 ^@ http://purl.uniprot.org/uniprot/D1AGU9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/526218:STERM_RS16315 ^@ http://purl.uniprot.org/uniprot/D1AQ86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/526218:STERM_RS20200 ^@ http://purl.uniprot.org/uniprot/D1AGF1 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/526218:STERM_RS11345 ^@ http://purl.uniprot.org/uniprot/D1AL19 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/526218:STERM_RS00835 ^@ http://purl.uniprot.org/uniprot/D1AJZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/526218:STERM_RS20360 ^@ http://purl.uniprot.org/uniprot/D1AGI3 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS08960 ^@ http://purl.uniprot.org/uniprot/D1AIZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/526218:STERM_RS16025 ^@ http://purl.uniprot.org/uniprot/D1APQ6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/526218:STERM_RS20555 ^@ http://purl.uniprot.org/uniprot/D1AGL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/526218:STERM_RS11455 ^@ http://purl.uniprot.org/uniprot/D1AL41 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS03030 ^@ http://purl.uniprot.org/uniprot/D1AP16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS13360 ^@ http://purl.uniprot.org/uniprot/D1AMJ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS00825 ^@ http://purl.uniprot.org/uniprot/D1AJZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19710 ^@ http://purl.uniprot.org/uniprot/D1AGT5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/526218:STERM_RS08375 ^@ http://purl.uniprot.org/uniprot/D1AIH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell inner membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/526218:STERM_RS15100 ^@ http://purl.uniprot.org/uniprot/D1AP74 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS03220 ^@ http://purl.uniprot.org/uniprot/D1AP54 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS01605 ^@ http://purl.uniprot.org/uniprot/D1ALT6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS07635 ^@ http://purl.uniprot.org/uniprot/D1AI31 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/526218:STERM_RS13840 ^@ http://purl.uniprot.org/uniprot/D1AN51 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/526218:STERM_RS09235 ^@ http://purl.uniprot.org/uniprot/D1AJ49 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||In the N-terminal section; belongs to the DHNA family. http://togogenome.org/gene/526218:STERM_RS03430 ^@ http://purl.uniprot.org/uniprot/D1APZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS09730 ^@ http://purl.uniprot.org/uniprot/D1AJE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/526218:STERM_RS09650 ^@ http://purl.uniprot.org/uniprot/D1AJD0 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/526218:STERM_RS05520 ^@ http://purl.uniprot.org/uniprot/D1AFV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS12070 ^@ http://purl.uniprot.org/uniprot/D1ALG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01950 ^@ http://purl.uniprot.org/uniprot/D1AM07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10010 ^@ http://purl.uniprot.org/uniprot/D1AJK2 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS08455 ^@ http://purl.uniprot.org/uniprot/D1AIJ3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/526218:STERM_RS01005 ^@ http://purl.uniprot.org/uniprot/D1AKR7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/526218:STERM_RS16780 ^@ http://purl.uniprot.org/uniprot/D1AQH8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS11565 ^@ http://purl.uniprot.org/uniprot/D1AL63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/526218:STERM_RS10360 ^@ http://purl.uniprot.org/uniprot/D1AK45 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/526218:STERM_RS06385 ^@ http://purl.uniprot.org/uniprot/D1AHC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS17185 ^@ http://purl.uniprot.org/uniprot/D1AQQ7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS10825 ^@ http://purl.uniprot.org/uniprot/D1AKD9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/526218:STERM_RS10560 ^@ http://purl.uniprot.org/uniprot/D1AK86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS20160 ^@ http://purl.uniprot.org/uniprot/D1AGE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17440 ^@ http://purl.uniprot.org/uniprot/D1AQV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS07725 ^@ http://purl.uniprot.org/uniprot/D1AI49 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/526218:STERM_RS07050 ^@ http://purl.uniprot.org/uniprot/D1AHR5 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/526218:STERM_RS12265 ^@ http://purl.uniprot.org/uniprot/D1ALK3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/526218:STERM_RS03340 ^@ http://purl.uniprot.org/uniprot/D1APX4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS12215 ^@ http://purl.uniprot.org/uniprot/D1ALJ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS12175 ^@ http://purl.uniprot.org/uniprot/D1ALI5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/526218:STERM_RS12210 ^@ http://purl.uniprot.org/uniprot/D1ALJ2 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/526218:STERM_RS12240 ^@ http://purl.uniprot.org/uniprot/D1ALJ8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/526218:STERM_RS03290 ^@ http://purl.uniprot.org/uniprot/D1APW4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/526218:STERM_RS14530 ^@ http://purl.uniprot.org/uniprot/D1ANJ5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/526218:STERM_RS06065 ^@ http://purl.uniprot.org/uniprot/D1AH61 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/526218:STERM_RS05710 ^@ http://purl.uniprot.org/uniprot/D1AFY9 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/526218:STERM_RS09095 ^@ http://purl.uniprot.org/uniprot/D1AJ20 ^@ Similarity ^@ Belongs to the SIS family. PHI subfamily. http://togogenome.org/gene/526218:STERM_RS05700 ^@ http://purl.uniprot.org/uniprot/D1AFY7 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/526218:STERM_RS04665 ^@ http://purl.uniprot.org/uniprot/D1AFC8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS12605 ^@ http://purl.uniprot.org/uniprot/D1AM45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/526218:STERM_RS05730 ^@ http://purl.uniprot.org/uniprot/D1AFZ3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/526218:STERM_RS08725 ^@ http://purl.uniprot.org/uniprot/D1AIP6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/526218:STERM_RS13355 ^@ http://purl.uniprot.org/uniprot/D1AMI9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS14450 ^@ http://purl.uniprot.org/uniprot/D1ANI0 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/526218:STERM_RS05795 ^@ http://purl.uniprot.org/uniprot/D1AH07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/526218:STERM_RS11000 ^@ http://purl.uniprot.org/uniprot/D1AKH6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/526218:STERM_RS09845 ^@ http://purl.uniprot.org/uniprot/D1AJG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/526218:STERM_RS09155 ^@ http://purl.uniprot.org/uniprot/D1AJ33 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/526218:STERM_RS10375 ^@ http://purl.uniprot.org/uniprot/D1AK48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS13590 ^@ http://purl.uniprot.org/uniprot/D1AMN6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/526218:STERM_RS11725 ^@ http://purl.uniprot.org/uniprot/D1AL95 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/526218:STERM_RS15885 ^@ http://purl.uniprot.org/uniprot/D1APM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS02345 ^@ http://purl.uniprot.org/uniprot/D1AMX3 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS02770 ^@ http://purl.uniprot.org/uniprot/D1ANW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS05295 ^@ http://purl.uniprot.org/uniprot/D1AFQ6 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS15435 ^@ http://purl.uniprot.org/uniprot/D1APE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS10295 ^@ http://purl.uniprot.org/uniprot/D1AK31 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS16190 ^@ http://purl.uniprot.org/uniprot/D1APT9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/526218:STERM_RS19590 ^@ http://purl.uniprot.org/uniprot/D1AGR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS11580 ^@ http://purl.uniprot.org/uniprot/D1AL66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS20515 ^@ http://purl.uniprot.org/uniprot/D1AGL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS08535 ^@ http://purl.uniprot.org/uniprot/D1AIK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS02495 ^@ http://purl.uniprot.org/uniprot/D1AN05 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS19530 ^@ http://purl.uniprot.org/uniprot/D1AGP9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/526218:STERM_RS08625 ^@ http://purl.uniprot.org/uniprot/D1AIM6 ^@ Similarity ^@ Belongs to the NusB family. http://togogenome.org/gene/526218:STERM_RS11915 ^@ http://purl.uniprot.org/uniprot/D1ALD3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/526218:STERM_RS10000 ^@ http://purl.uniprot.org/uniprot/D1AJK0 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS10710 ^@ http://purl.uniprot.org/uniprot/D1AKB6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/526218:STERM_RS13425 ^@ http://purl.uniprot.org/uniprot/D1AMK3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/526218:STERM_RS11360 ^@ http://purl.uniprot.org/uniprot/D1AL22 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/526218:STERM_RS13205 ^@ http://purl.uniprot.org/uniprot/D1AMF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07485 ^@ http://purl.uniprot.org/uniprot/D1AI01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS14840 ^@ http://purl.uniprot.org/uniprot/D1ANQ2 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/526218:STERM_RS00935 ^@ http://purl.uniprot.org/uniprot/D1AKQ3 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/526218:STERM_RS09785 ^@ http://purl.uniprot.org/uniprot/D1AJF7 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS15125 ^@ http://purl.uniprot.org/uniprot/D1AP80 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS16185 ^@ http://purl.uniprot.org/uniprot/D1APT8 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/526218:STERM_RS16360 ^@ http://purl.uniprot.org/uniprot/D1AQ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/526218:STERM_RS17035 ^@ http://purl.uniprot.org/uniprot/D1AQM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08815 ^@ http://purl.uniprot.org/uniprot/D1AIR5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/526218:STERM_RS13335 ^@ http://purl.uniprot.org/uniprot/D1AMI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08300 ^@ http://purl.uniprot.org/uniprot/D1AIG2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/526218:STERM_RS11095 ^@ http://purl.uniprot.org/uniprot/D1AKJ6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/526218:STERM_RS14750 ^@ http://purl.uniprot.org/uniprot/D1ANN5 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS15805 ^@ http://purl.uniprot.org/uniprot/D1APL1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS07190 ^@ http://purl.uniprot.org/uniprot/D1AHU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19815 ^@ http://purl.uniprot.org/uniprot/D1AGV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS11800 ^@ http://purl.uniprot.org/uniprot/D1ALB0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/526218:STERM_RS17740 ^@ http://purl.uniprot.org/uniprot/D1ARD9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/526218:STERM_RS16050 ^@ http://purl.uniprot.org/uniprot/D1APR1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS14535 ^@ http://purl.uniprot.org/uniprot/D1ANJ6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS11670 ^@ http://purl.uniprot.org/uniprot/D1AL84 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/526218:STERM_RS09090 ^@ http://purl.uniprot.org/uniprot/D1AJ19 ^@ Similarity ^@ Belongs to the HPS/KGPDC family. HPS subfamily. http://togogenome.org/gene/526218:STERM_RS05275 ^@ http://purl.uniprot.org/uniprot/D1AFQ2 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS13235 ^@ http://purl.uniprot.org/uniprot/D1AMG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/526218:STERM_RS12585 ^@ http://purl.uniprot.org/uniprot/D1AM41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS11220 ^@ http://purl.uniprot.org/uniprot/D1AKM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07970 ^@ http://purl.uniprot.org/uniprot/D1AI96 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS18340 ^@ http://purl.uniprot.org/uniprot/D1ARQ6 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/526218:STERM_RS20080 ^@ http://purl.uniprot.org/uniprot/D1AGC7 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/526218:STERM_RS12920 ^@ http://purl.uniprot.org/uniprot/D1AMA2 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/526218:STERM_RS18090 ^@ http://purl.uniprot.org/uniprot/D1ARK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/526218:STERM_RS11815 ^@ http://purl.uniprot.org/uniprot/D1ALB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS16400 ^@ http://purl.uniprot.org/uniprot/D1AQA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS15880 ^@ http://purl.uniprot.org/uniprot/D1APM6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS08275 ^@ http://purl.uniprot.org/uniprot/D1AIF7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/526218:STERM_RS12120 ^@ http://purl.uniprot.org/uniprot/D1ALH4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/526218:STERM_RS13705 ^@ http://purl.uniprot.org/uniprot/D1AMQ4 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/526218:STERM_RS03050 ^@ http://purl.uniprot.org/uniprot/D1AP20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/526218:STERM_RS18095 ^@ http://purl.uniprot.org/uniprot/D1ARK7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/526218:STERM_RS01975 ^@ http://purl.uniprot.org/uniprot/D1AM11 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS17020 ^@ http://purl.uniprot.org/uniprot/D1AQM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS21360 ^@ http://purl.uniprot.org/uniprot/D1AN94 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/526218:STERM_RS15440 ^@ http://purl.uniprot.org/uniprot/D1APE3 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/526218:STERM_RS01035 ^@ http://purl.uniprot.org/uniprot/D1AKS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/526218:STERM_RS16130 ^@ http://purl.uniprot.org/uniprot/D1APS7 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS01275 ^@ http://purl.uniprot.org/uniprot/D1AKX1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/526218:STERM_RS13710 ^@ http://purl.uniprot.org/uniprot/D1AMQ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS01015 ^@ http://purl.uniprot.org/uniprot/D1AKR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/526218:STERM_RS18840 ^@ http://purl.uniprot.org/uniprot/D1AG07 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS14965 ^@ http://purl.uniprot.org/uniprot/D1ANS7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/526218:STERM_RS14885 ^@ http://purl.uniprot.org/uniprot/D1ANR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS02355 ^@ http://purl.uniprot.org/uniprot/D1AMX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18980 ^@ http://purl.uniprot.org/uniprot/D1AG36 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS17990 ^@ http://purl.uniprot.org/uniprot/D1ARJ0 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/526218:STERM_RS14470 ^@ http://purl.uniprot.org/uniprot/D1ANI4 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/526218:STERM_RS09145 ^@ http://purl.uniprot.org/uniprot/D1AJ31 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/526218:STERM_RS18865 ^@ http://purl.uniprot.org/uniprot/D1AG12 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/526218:STERM_RS05765 ^@ http://purl.uniprot.org/uniprot/D1AH01 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/526218:STERM_RS08740 ^@ http://purl.uniprot.org/uniprot/D1AIP9 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/526218:STERM_RS11940 ^@ http://purl.uniprot.org/uniprot/D1ALD8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/526218:STERM_RS16680 ^@ http://purl.uniprot.org/uniprot/D1AQF7 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS11600 ^@ http://purl.uniprot.org/uniprot/D1AL70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS17085 ^@ http://purl.uniprot.org/uniprot/D1AQN8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS13440 ^@ http://purl.uniprot.org/uniprot/D1AMK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19270 ^@ http://purl.uniprot.org/uniprot/D1AG88 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS10325 ^@ http://purl.uniprot.org/uniprot/D1AK37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS09930 ^@ http://purl.uniprot.org/uniprot/D1AJI6 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/526218:STERM_RS13500 ^@ http://purl.uniprot.org/uniprot/D1AML8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS15370 ^@ http://purl.uniprot.org/uniprot/D1APC9 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS09780 ^@ http://purl.uniprot.org/uniprot/D1AJF6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/526218:STERM_RS01740 ^@ http://purl.uniprot.org/uniprot/D1ALW5 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS17460 ^@ http://purl.uniprot.org/uniprot/D1AQW0 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/526218:STERM_RS00585 ^@ http://purl.uniprot.org/uniprot/D1AJU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS12480 ^@ http://purl.uniprot.org/uniprot/D1ALQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/526218:STERM_RS05055 ^@ http://purl.uniprot.org/uniprot/D1AFK8 ^@ Similarity ^@ Belongs to the CobT family. http://togogenome.org/gene/526218:STERM_RS13115 ^@ http://purl.uniprot.org/uniprot/D1AME1 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/526218:STERM_RS03515 ^@ http://purl.uniprot.org/uniprot/D1AQ09 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/526218:STERM_RS13520 ^@ http://purl.uniprot.org/uniprot/D1AMM2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS16810 ^@ http://purl.uniprot.org/uniprot/D1AQI4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS19225 ^@ http://purl.uniprot.org/uniprot/D1AG79 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS15005 ^@ http://purl.uniprot.org/uniprot/D1ANT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS20420 ^@ http://purl.uniprot.org/uniprot/D1AGJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/526218:STERM_RS08475 ^@ http://purl.uniprot.org/uniprot/D1AIJ7 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/526218:STERM_RS05490 ^@ http://purl.uniprot.org/uniprot/D1AFU5 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/526218:STERM_RS05860 ^@ http://purl.uniprot.org/uniprot/D1AH20 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/526218:STERM_RS18400 ^@ http://purl.uniprot.org/uniprot/D1ARR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07645 ^@ http://purl.uniprot.org/uniprot/D1AI33 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/526218:STERM_RS09405 ^@ http://purl.uniprot.org/uniprot/D1AJ83 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/526218:STERM_RS11415 ^@ http://purl.uniprot.org/uniprot/D1AL33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell inner membrane http://togogenome.org/gene/526218:STERM_RS05410 ^@ http://purl.uniprot.org/uniprot/D1AFS9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS05820 ^@ http://purl.uniprot.org/uniprot/D1AH12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS17270 ^@ http://purl.uniprot.org/uniprot/D1AQS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS01500 ^@ http://purl.uniprot.org/uniprot/D1ALR5 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/526218:STERM_RS05035 ^@ http://purl.uniprot.org/uniprot/D1AFK4 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/526218:STERM_RS16030 ^@ http://purl.uniprot.org/uniprot/D1APQ7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/526218:STERM_RS00995 ^@ http://purl.uniprot.org/uniprot/D1AKR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS00600 ^@ http://purl.uniprot.org/uniprot/D1AJV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS11180 ^@ http://purl.uniprot.org/uniprot/D1AKL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/526218:STERM_RS17535 ^@ http://purl.uniprot.org/uniprot/D1AR99 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS15540 ^@ http://purl.uniprot.org/uniprot/D1APG0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS12135 ^@ http://purl.uniprot.org/uniprot/D1ALH7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/526218:STERM_RS08265 ^@ http://purl.uniprot.org/uniprot/D1AIF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS04970 ^@ http://purl.uniprot.org/uniprot/D1AFJ1 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/526218:STERM_RS11205 ^@ http://purl.uniprot.org/uniprot/D1AKL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS01010 ^@ http://purl.uniprot.org/uniprot/D1AKR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/526218:STERM_RS00380 ^@ http://purl.uniprot.org/uniprot/D1AJQ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/526218:STERM_RS19245 ^@ http://purl.uniprot.org/uniprot/D1AG83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/526218:STERM_RS14720 ^@ http://purl.uniprot.org/uniprot/D1ANM9 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/526218:STERM_RS05785 ^@ http://purl.uniprot.org/uniprot/D1AH05 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/526218:STERM_RS13605 ^@ http://purl.uniprot.org/uniprot/D1AMN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/526218:STERM_RS13700 ^@ http://purl.uniprot.org/uniprot/D1AMQ3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/526218:STERM_RS13430 ^@ http://purl.uniprot.org/uniprot/D1AMK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS11395 ^@ http://purl.uniprot.org/uniprot/D1AL29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/526218:STERM_RS13485 ^@ http://purl.uniprot.org/uniprot/D1AML5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/526218:STERM_RS01490 ^@ http://purl.uniprot.org/uniprot/D1ALR3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS00250 ^@ http://purl.uniprot.org/uniprot/D1AJN1 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS01290 ^@ http://purl.uniprot.org/uniprot/D1AKX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/526218:STERM_RS13255 ^@ http://purl.uniprot.org/uniprot/D1AMG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19605 ^@ http://purl.uniprot.org/uniprot/D1AGR4 ^@ Caution|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS19825 ^@ http://purl.uniprot.org/uniprot/D1AGV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS16545 ^@ http://purl.uniprot.org/uniprot/D1AQD2 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS11105 ^@ http://purl.uniprot.org/uniprot/D1AKJ8 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/526218:STERM_RS05135 ^@ http://purl.uniprot.org/uniprot/D1AFM4 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/526218:STERM_RS00375 ^@ http://purl.uniprot.org/uniprot/D1AJQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS01400 ^@ http://purl.uniprot.org/uniprot/D1AKZ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS03610 ^@ http://purl.uniprot.org/uniprot/D1AQ29 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/526218:STERM_RS10540 ^@ http://purl.uniprot.org/uniprot/D1AK81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS16040 ^@ http://purl.uniprot.org/uniprot/D1APQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08240 ^@ http://purl.uniprot.org/uniprot/D1AIF0 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/526218:STERM_RS08610 ^@ http://purl.uniprot.org/uniprot/D1AIM3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/526218:STERM_RS18170 ^@ http://purl.uniprot.org/uniprot/D1ARM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/526218:STERM_RS08720 ^@ http://purl.uniprot.org/uniprot/D1AIP5 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/526218:STERM_RS08185 ^@ http://purl.uniprot.org/uniprot/D1AID9 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/526218:STERM_RS04095 ^@ http://purl.uniprot.org/uniprot/D1AR17 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/526218:STERM_RS20450 ^@ http://purl.uniprot.org/uniprot/D1AGK1 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/526218:STERM_RS05900 ^@ http://purl.uniprot.org/uniprot/D1AH28 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/526218:STERM_RS03475 ^@ http://purl.uniprot.org/uniprot/D1AQ01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/526218:STERM_RS05655 ^@ http://purl.uniprot.org/uniprot/D1AFX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/526218:STERM_RS03705 ^@ http://purl.uniprot.org/uniprot/D1AQ48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS14465 ^@ http://purl.uniprot.org/uniprot/D1ANI3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/526218:STERM_RS13570 ^@ http://purl.uniprot.org/uniprot/D1AMN2 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS06790 ^@ http://purl.uniprot.org/uniprot/D1AHL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/526218:STERM_RS10415 ^@ http://purl.uniprot.org/uniprot/D1AK56 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/526218:STERM_RS19180 ^@ http://purl.uniprot.org/uniprot/D1AG70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19015 ^@ http://purl.uniprot.org/uniprot/D1AG42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS10735 ^@ http://purl.uniprot.org/uniprot/D1AKC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/526218:STERM_RS03060 ^@ http://purl.uniprot.org/uniprot/D1AP22 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/526218:STERM_RS20025 ^@ http://purl.uniprot.org/uniprot/D1AGB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS08675 ^@ http://purl.uniprot.org/uniprot/D1AIN6 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/526218:STERM_RS10240 ^@ http://purl.uniprot.org/uniprot/D1AK20 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/526218:STERM_RS10570 ^@ http://purl.uniprot.org/uniprot/D1AK88 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/526218:STERM_RS10085 ^@ http://purl.uniprot.org/uniprot/D1AJL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/526218:STERM_RS18020 ^@ http://purl.uniprot.org/uniprot/D1ARJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS19720 ^@ http://purl.uniprot.org/uniprot/D1AGT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/526218:STERM_RS06750 ^@ http://purl.uniprot.org/uniprot/D1AHK3 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/526218:STERM_RS19005 ^@ http://purl.uniprot.org/uniprot/D1AG40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18145 ^@ http://purl.uniprot.org/uniprot/D1ARL7 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/526218:STERM_RS18305 ^@ http://purl.uniprot.org/uniprot/D1ARP9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/526218:STERM_RS10760 ^@ http://purl.uniprot.org/uniprot/D1AKC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS12970 ^@ http://purl.uniprot.org/uniprot/D1AMB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS01170 ^@ http://purl.uniprot.org/uniprot/D1AKV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/526218:STERM_RS01305 ^@ http://purl.uniprot.org/uniprot/D1AKX7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/526218:STERM_RS03390 ^@ http://purl.uniprot.org/uniprot/D1APY4 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/526218:STERM_RS05065 ^@ http://purl.uniprot.org/uniprot/D1AFL0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/526218:STERM_RS18395 ^@ http://purl.uniprot.org/uniprot/D1ARR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19725 ^@ http://purl.uniprot.org/uniprot/D1AGT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS02920 ^@ http://purl.uniprot.org/uniprot/D1ANZ3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS03600 ^@ http://purl.uniprot.org/uniprot/D1AQ27 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/526218:STERM_RS04945 ^@ http://purl.uniprot.org/uniprot/D1AFI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell inner membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/526218:STERM_RS18285 ^@ http://purl.uniprot.org/uniprot/D1ARP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS16605 ^@ http://purl.uniprot.org/uniprot/D1AQE2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/526218:STERM_RS05210 ^@ http://purl.uniprot.org/uniprot/D1AFN9 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/526218:STERM_RS02925 ^@ http://purl.uniprot.org/uniprot/D1ANZ4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/526218:STERM_RS20560 ^@ http://purl.uniprot.org/uniprot/D1AGL8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/526218:STERM_RS13405 ^@ http://purl.uniprot.org/uniprot/D1AMJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10130 ^@ http://purl.uniprot.org/uniprot/D1AJM6 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/526218:STERM_RS09840 ^@ http://purl.uniprot.org/uniprot/D1AJG8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/526218:STERM_RS16920 ^@ http://purl.uniprot.org/uniprot/D1AQK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS13805 ^@ http://purl.uniprot.org/uniprot/D1AN44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS01270 ^@ http://purl.uniprot.org/uniprot/D1AKX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/526218:STERM_RS18320 ^@ http://purl.uniprot.org/uniprot/D1ARQ2 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS07745 ^@ http://purl.uniprot.org/uniprot/D1AI53 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/526218:STERM_RS09835 ^@ http://purl.uniprot.org/uniprot/D1AJG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS08030 ^@ http://purl.uniprot.org/uniprot/D1AIA8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/526218:STERM_RS18640 ^@ http://purl.uniprot.org/uniprot/D1ARV7 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/526218:STERM_RS03140 ^@ http://purl.uniprot.org/uniprot/D1AP39 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/526218:STERM_RS13085 ^@ http://purl.uniprot.org/uniprot/D1AMD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/526218:STERM_RS02430 ^@ http://purl.uniprot.org/uniprot/D1AMZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01335 ^@ http://purl.uniprot.org/uniprot/D1AKY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/526218:STERM_RS20145 ^@ http://purl.uniprot.org/uniprot/D1AGE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS11440 ^@ http://purl.uniprot.org/uniprot/D1AL38 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS00810 ^@ http://purl.uniprot.org/uniprot/D1AJY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS03225 ^@ http://purl.uniprot.org/uniprot/D1AP55 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS03415 ^@ http://purl.uniprot.org/uniprot/D1APY9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS05290 ^@ http://purl.uniprot.org/uniprot/D1AFQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS11065 ^@ http://purl.uniprot.org/uniprot/D1AKJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS20365 ^@ http://purl.uniprot.org/uniprot/D1AGI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/526218:STERM_RS04990 ^@ http://purl.uniprot.org/uniprot/D1AFJ5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/526218:STERM_RS12615 ^@ http://purl.uniprot.org/uniprot/D1AM47 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/526218:STERM_RS06325 ^@ http://purl.uniprot.org/uniprot/D1AHB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17130 ^@ http://purl.uniprot.org/uniprot/D1AQP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS02685 ^@ http://purl.uniprot.org/uniprot/D1ANU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS05145 ^@ http://purl.uniprot.org/uniprot/D1AFM6 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/526218:STERM_RS01880 ^@ http://purl.uniprot.org/uniprot/D1ALZ3 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/526218:STERM_RS14705 ^@ http://purl.uniprot.org/uniprot/D1ANM6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/526218:STERM_RS13000 ^@ http://purl.uniprot.org/uniprot/D1AMB8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS18085 ^@ http://purl.uniprot.org/uniprot/D1ARK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS13265 ^@ http://purl.uniprot.org/uniprot/D1AMH1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/526218:STERM_RS13110 ^@ http://purl.uniprot.org/uniprot/D1AME0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS09800 ^@ http://purl.uniprot.org/uniprot/D1AJG0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS19890 ^@ http://purl.uniprot.org/uniprot/D1AGX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS14890 ^@ http://purl.uniprot.org/uniprot/D1ANR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19840 ^@ http://purl.uniprot.org/uniprot/D1AGW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/526218:STERM_RS11100 ^@ http://purl.uniprot.org/uniprot/D1AKJ7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/526218:STERM_RS01340 ^@ http://purl.uniprot.org/uniprot/D1AKY4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/526218:STERM_RS20240 ^@ http://purl.uniprot.org/uniprot/D1AGF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS10565 ^@ http://purl.uniprot.org/uniprot/D1AK87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/526218:STERM_RS09970 ^@ http://purl.uniprot.org/uniprot/D1AJJ4 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/526218:STERM_RS15365 ^@ http://purl.uniprot.org/uniprot/D1APC8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS01875 ^@ http://purl.uniprot.org/uniprot/D1ALZ2 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/526218:STERM_RS08315 ^@ http://purl.uniprot.org/uniprot/D1AIG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/526218:STERM_RS20215 ^@ http://purl.uniprot.org/uniprot/D1AGF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS05835 ^@ http://purl.uniprot.org/uniprot/D1AH15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/526218:STERM_RS09950 ^@ http://purl.uniprot.org/uniprot/D1AJJ0 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/526218:STERM_RS22415 ^@ http://purl.uniprot.org/uniprot/D1AQI8 ^@ Caution|||Similarity ^@ Belongs to the mannitol dehydrogenase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS09720 ^@ http://purl.uniprot.org/uniprot/D1AJE4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/526218:STERM_RS05945 ^@ http://purl.uniprot.org/uniprot/D1AH37 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/526218:STERM_RS08630 ^@ http://purl.uniprot.org/uniprot/D1AIM7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS05455 ^@ http://purl.uniprot.org/uniprot/D1AFT8 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/526218:STERM_RS20050 ^@ http://purl.uniprot.org/uniprot/D1AGC1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS16070 ^@ http://purl.uniprot.org/uniprot/D1APR5 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS12975 ^@ http://purl.uniprot.org/uniprot/D1AMB3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/526218:STERM_RS03015 ^@ http://purl.uniprot.org/uniprot/D1AP13 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS09245 ^@ http://purl.uniprot.org/uniprot/D1AJ51 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/526218:STERM_RS10550 ^@ http://purl.uniprot.org/uniprot/D1AK83 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/526218:STERM_RS13465 ^@ http://purl.uniprot.org/uniprot/D1AML1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS01095 ^@ http://purl.uniprot.org/uniprot/D1AKT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS10700 ^@ http://purl.uniprot.org/uniprot/D1AKB4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS19540 ^@ http://purl.uniprot.org/uniprot/D1AGQ1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/526218:STERM_RS17705 ^@ http://purl.uniprot.org/uniprot/D1ARD2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/526218:STERM_RS10765 ^@ http://purl.uniprot.org/uniprot/D1AKC7 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/526218:STERM_RS05750 ^@ http://purl.uniprot.org/uniprot/D1AGZ8 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/526218:STERM_RS11615 ^@ http://purl.uniprot.org/uniprot/D1AL73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17810 ^@ http://purl.uniprot.org/uniprot/D1ARF3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.|||Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. http://togogenome.org/gene/526218:STERM_RS03505 ^@ http://purl.uniprot.org/uniprot/D1AQ07 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/526218:STERM_RS11950 ^@ http://purl.uniprot.org/uniprot/D1ALE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS14795 ^@ http://purl.uniprot.org/uniprot/D1ANP3 ^@ Similarity ^@ Belongs to the archaeal-type GPI family. http://togogenome.org/gene/526218:STERM_RS13645 ^@ http://purl.uniprot.org/uniprot/D1AMP2 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/526218:STERM_RS17915 ^@ http://purl.uniprot.org/uniprot/D1ARH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS03020 ^@ http://purl.uniprot.org/uniprot/D1AP14 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/526218:STERM_RS07585 ^@ http://purl.uniprot.org/uniprot/D1AI21 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS12090 ^@ http://purl.uniprot.org/uniprot/D1ALG8 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/526218:STERM_RS19845 ^@ http://purl.uniprot.org/uniprot/D1AGW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/526218:STERM_RS05050 ^@ http://purl.uniprot.org/uniprot/D1AFK7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS05780 ^@ http://purl.uniprot.org/uniprot/D1AH04 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/526218:STERM_RS16095 ^@ http://purl.uniprot.org/uniprot/D1APS0 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/526218:STERM_RS16560 ^@ http://purl.uniprot.org/uniprot/D1AQD5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/526218:STERM_RS08775 ^@ http://purl.uniprot.org/uniprot/D1AIQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/526218:STERM_RS17805 ^@ http://purl.uniprot.org/uniprot/D1ARF2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/526218:STERM_RS12000 ^@ http://purl.uniprot.org/uniprot/D1ALF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/526218:STERM_RS08840 ^@ http://purl.uniprot.org/uniprot/D1AIS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS19060 ^@ http://purl.uniprot.org/uniprot/D1AG51 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/526218:STERM_RS01390 ^@ http://purl.uniprot.org/uniprot/D1AKZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS11535 ^@ http://purl.uniprot.org/uniprot/D1AL57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS17445 ^@ http://purl.uniprot.org/uniprot/D1AQV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/526218:STERM_RS01845 ^@ http://purl.uniprot.org/uniprot/D1ALY6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/526218:STERM_RS11365 ^@ http://purl.uniprot.org/uniprot/D1AL23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/526218:STERM_RS11635 ^@ http://purl.uniprot.org/uniprot/D1AL77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/526218:STERM_RS00510 ^@ http://purl.uniprot.org/uniprot/D1AJT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/526218:STERM_RS13785 ^@ http://purl.uniprot.org/uniprot/D1AMS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS13725 ^@ http://purl.uniprot.org/uniprot/D1AMQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS00120 ^@ http://purl.uniprot.org/uniprot/D1AIV0 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/526218:STERM_RS05550 ^@ http://purl.uniprot.org/uniprot/D1AFV7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/526218:STERM_RS13420 ^@ http://purl.uniprot.org/uniprot/D1AMK2 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/526218:STERM_RS03200 ^@ http://purl.uniprot.org/uniprot/D1AP50 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS03435 ^@ http://purl.uniprot.org/uniprot/D1APZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS13075 ^@ http://purl.uniprot.org/uniprot/D1AMD3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS14715 ^@ http://purl.uniprot.org/uniprot/D1ANM8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS19215 ^@ http://purl.uniprot.org/uniprot/D1AG77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS02820 ^@ http://purl.uniprot.org/uniprot/D1ANX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS01135 ^@ http://purl.uniprot.org/uniprot/D1AKU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS00945 ^@ http://purl.uniprot.org/uniprot/D1AKQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/526218:STERM_RS17065 ^@ http://purl.uniprot.org/uniprot/D1AQN4 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS16175 ^@ http://purl.uniprot.org/uniprot/D1APT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/526218:STERM_RS07880 ^@ http://purl.uniprot.org/uniprot/D1AI79 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/526218:STERM_RS13340 ^@ http://purl.uniprot.org/uniprot/D1AMI6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS18770 ^@ http://purl.uniprot.org/uniprot/D1ARY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. RhaD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS11150 ^@ http://purl.uniprot.org/uniprot/D1AKK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS10190 ^@ http://purl.uniprot.org/uniprot/D1AK10 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/526218:STERM_RS05160 ^@ http://purl.uniprot.org/uniprot/D1AFM9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the PduL family.|||Formed by 2 beta-barrels, each is capped on both ends by short alpha-helices.|||Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.|||There are 2 Zn(2+) ions per monomer; Zn(2+) and CoA bind inbetween the 2 domains in each monomer. http://togogenome.org/gene/526218:STERM_RS19705 ^@ http://purl.uniprot.org/uniprot/D1AGT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/526218:STERM_RS10370 ^@ http://purl.uniprot.org/uniprot/D1AK47 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/526218:STERM_RS00130 ^@ http://purl.uniprot.org/uniprot/D1AIV2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/526218:STERM_RS11400 ^@ http://purl.uniprot.org/uniprot/D1AL30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/526218:STERM_RS00930 ^@ http://purl.uniprot.org/uniprot/D1AKQ2 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/526218:STERM_RS11995 ^@ http://purl.uniprot.org/uniprot/D1ALE9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/526218:STERM_RS16705 ^@ http://purl.uniprot.org/uniprot/D1AQG2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS10080 ^@ http://purl.uniprot.org/uniprot/D1AJL6 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/526218:STERM_RS19020 ^@ http://purl.uniprot.org/uniprot/D1AG43 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS13410 ^@ http://purl.uniprot.org/uniprot/D1AMK0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/526218:STERM_RS03810 ^@ http://purl.uniprot.org/uniprot/D1AQ69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/526218:STERM_RS11845 ^@ http://purl.uniprot.org/uniprot/D1ALB9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/526218:STERM_RS08845 ^@ http://purl.uniprot.org/uniprot/D1AIS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS10840 ^@ http://purl.uniprot.org/uniprot/D1AKE2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/526218:STERM_RS05010 ^@ http://purl.uniprot.org/uniprot/D1AFJ9 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/526218:STERM_RS08420 ^@ http://purl.uniprot.org/uniprot/D1AII6 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/526218:STERM_RS15345 ^@ http://purl.uniprot.org/uniprot/D1APC4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS19920 ^@ http://purl.uniprot.org/uniprot/D1AGX7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/526218:STERM_RS14955 ^@ http://purl.uniprot.org/uniprot/D1ANS5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS07670 ^@ http://purl.uniprot.org/uniprot/D1AI38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS00005 ^@ http://purl.uniprot.org/uniprot/D1AIS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/526218:STERM_RS11810 ^@ http://purl.uniprot.org/uniprot/D1ALB2 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/526218:STERM_RS09185 ^@ http://purl.uniprot.org/uniprot/D1AJ40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01840 ^@ http://purl.uniprot.org/uniprot/D1ALY5 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/526218:STERM_RS17215 ^@ http://purl.uniprot.org/uniprot/D1AQR3 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/526218:STERM_RS03040 ^@ http://purl.uniprot.org/uniprot/D1AP18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/526218:STERM_RS01165 ^@ http://purl.uniprot.org/uniprot/D1AKU9 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS15735 ^@ http://purl.uniprot.org/uniprot/D1APJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS11975 ^@ http://purl.uniprot.org/uniprot/D1ALE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08225 ^@ http://purl.uniprot.org/uniprot/D1AIE7 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS03685 ^@ http://purl.uniprot.org/uniprot/D1AQ44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01280 ^@ http://purl.uniprot.org/uniprot/D1AKX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08915 ^@ http://purl.uniprot.org/uniprot/D1AIY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01925 ^@ http://purl.uniprot.org/uniprot/D1AM02 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/526218:STERM_RS09760 ^@ http://purl.uniprot.org/uniprot/D1AJF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/526218:STERM_RS01175 ^@ http://purl.uniprot.org/uniprot/D1AKV1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS14485 ^@ http://purl.uniprot.org/uniprot/D1ANI7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/526218:STERM_RS10455 ^@ http://purl.uniprot.org/uniprot/D1AK64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/526218:STERM_RS10065 ^@ http://purl.uniprot.org/uniprot/D1AJL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS09370 ^@ http://purl.uniprot.org/uniprot/D1AJ76 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/526218:STERM_RS18635 ^@ http://purl.uniprot.org/uniprot/D1ARV6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS15160 ^@ http://purl.uniprot.org/uniprot/D1AP87 ^@ Similarity ^@ Belongs to the UPF0310 family. http://togogenome.org/gene/526218:STERM_RS15890 ^@ http://purl.uniprot.org/uniprot/D1APM8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS09955 ^@ http://purl.uniprot.org/uniprot/D1AJJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell inner membrane|||Membrane|||Transport of potassium into the cell. http://togogenome.org/gene/526218:STERM_RS08010 ^@ http://purl.uniprot.org/uniprot/D1AIA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18510 ^@ http://purl.uniprot.org/uniprot/D1ART8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/526218:STERM_RS06760 ^@ http://purl.uniprot.org/uniprot/D1AHK5 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/526218:STERM_RS02635 ^@ http://purl.uniprot.org/uniprot/D1AN33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS20415 ^@ http://purl.uniprot.org/uniprot/D1AGJ4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/526218:STERM_RS16790 ^@ http://purl.uniprot.org/uniprot/D1AQI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS16885 ^@ http://purl.uniprot.org/uniprot/D1AQJ9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/526218:STERM_RS03495 ^@ http://purl.uniprot.org/uniprot/D1AQ05 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/526218:STERM_RS20220 ^@ http://purl.uniprot.org/uniprot/D1AGF5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS00035 ^@ http://purl.uniprot.org/uniprot/D1AIT3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/526218:STERM_RS03990 ^@ http://purl.uniprot.org/uniprot/D1ANB3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS03350 ^@ http://purl.uniprot.org/uniprot/D1APX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS00455 ^@ http://purl.uniprot.org/uniprot/D1AJS2 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/526218:STERM_RS11315 ^@ http://purl.uniprot.org/uniprot/D1AKP0 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/526218:STERM_RS08830 ^@ http://purl.uniprot.org/uniprot/D1AIR8 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/526218:STERM_RS08480 ^@ http://purl.uniprot.org/uniprot/D1AIJ8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS19220 ^@ http://purl.uniprot.org/uniprot/D1AG78 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS14610 ^@ http://purl.uniprot.org/uniprot/D1ANK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS11920 ^@ http://purl.uniprot.org/uniprot/D1ALD4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS19730 ^@ http://purl.uniprot.org/uniprot/D1AGT9 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS20175 ^@ http://purl.uniprot.org/uniprot/D1AGE6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/526218:STERM_RS07125 ^@ http://purl.uniprot.org/uniprot/D1AHT1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/526218:STERM_RS13300 ^@ http://purl.uniprot.org/uniprot/D1AMH8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS05540 ^@ http://purl.uniprot.org/uniprot/D1AFV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/526218:STERM_RS19695 ^@ http://purl.uniprot.org/uniprot/D1AGT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/526218:STERM_RS07950 ^@ http://purl.uniprot.org/uniprot/D1AI92 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS17355 ^@ http://purl.uniprot.org/uniprot/D1AQT9 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/526218:STERM_RS05205 ^@ http://purl.uniprot.org/uniprot/D1AFN8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/526218:STERM_RS19125 ^@ http://purl.uniprot.org/uniprot/D1AG64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS17165 ^@ http://purl.uniprot.org/uniprot/D1AQQ4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS09830 ^@ http://purl.uniprot.org/uniprot/D1AJG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/526218:STERM_RS15605 ^@ http://purl.uniprot.org/uniprot/D1APH3 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/526218:STERM_RS13225 ^@ http://purl.uniprot.org/uniprot/D1AMG3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/526218:STERM_RS08540 ^@ http://purl.uniprot.org/uniprot/D1AIK9 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/526218:STERM_RS13095 ^@ http://purl.uniprot.org/uniprot/D1AMD7 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/526218:STERM_RS16505 ^@ http://purl.uniprot.org/uniprot/D1AQC4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS03675 ^@ http://purl.uniprot.org/uniprot/D1AQ42 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/526218:STERM_RS05755 ^@ http://purl.uniprot.org/uniprot/D1AGZ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS08440 ^@ http://purl.uniprot.org/uniprot/D1AIJ0 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/526218:STERM_RS03135 ^@ http://purl.uniprot.org/uniprot/D1AP38 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/526218:STERM_RS09150 ^@ http://purl.uniprot.org/uniprot/D1AJ32 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/526218:STERM_RS09860 ^@ http://purl.uniprot.org/uniprot/D1AJH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/526218:STERM_RS19545 ^@ http://purl.uniprot.org/uniprot/D1AGQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/526218:STERM_RS20370 ^@ http://purl.uniprot.org/uniprot/D1AGI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS15740 ^@ http://purl.uniprot.org/uniprot/D1APJ8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/526218:STERM_RS05515 ^@ http://purl.uniprot.org/uniprot/D1AFV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/526218:STERM_RS13210 ^@ http://purl.uniprot.org/uniprot/D1AMG0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/526218:STERM_RS19090 ^@ http://purl.uniprot.org/uniprot/D1AG57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS19010 ^@ http://purl.uniprot.org/uniprot/D1AG41 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/526218:STERM_RS07665 ^@ http://purl.uniprot.org/uniprot/D1AI37 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/526218:STERM_RS05560 ^@ http://purl.uniprot.org/uniprot/D1AFV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS09755 ^@ http://purl.uniprot.org/uniprot/D1AJF1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/526218:STERM_RS05815 ^@ http://purl.uniprot.org/uniprot/D1AH11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/526218:STERM_RS13455 ^@ http://purl.uniprot.org/uniprot/D1AMK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/526218:STERM_RS00640 ^@ http://purl.uniprot.org/uniprot/D1AJW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS05855 ^@ http://purl.uniprot.org/uniprot/D1AH19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS14960 ^@ http://purl.uniprot.org/uniprot/D1ANS6 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/526218:STERM_RS03270 ^@ http://purl.uniprot.org/uniprot/D1AP64 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/526218:STERM_RS10485 ^@ http://purl.uniprot.org/uniprot/D1AK70 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/526218:STERM_RS09805 ^@ http://purl.uniprot.org/uniprot/D1AJG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07130 ^@ http://purl.uniprot.org/uniprot/D1AHT2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/526218:STERM_RS02380 ^@ http://purl.uniprot.org/uniprot/D1AMY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/526218:STERM_RS20545 ^@ http://purl.uniprot.org/uniprot/D1AGL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/526218:STERM_RS17475 ^@ http://purl.uniprot.org/uniprot/D1AQW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS03530 ^@ http://purl.uniprot.org/uniprot/D1AQ12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS07350 ^@ http://purl.uniprot.org/uniprot/D1AHX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS14855 ^@ http://purl.uniprot.org/uniprot/D1ANQ5 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/526218:STERM_RS16575 ^@ http://purl.uniprot.org/uniprot/D1AQD6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS07790 ^@ http://purl.uniprot.org/uniprot/D1AI62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19645 ^@ http://purl.uniprot.org/uniprot/D1AGS2 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/526218:STERM_RS03615 ^@ http://purl.uniprot.org/uniprot/D1AQ30 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10720 ^@ http://purl.uniprot.org/uniprot/D1AKB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/526218:STERM_RS02455 ^@ http://purl.uniprot.org/uniprot/D1AMZ7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/526218:STERM_RS19860 ^@ http://purl.uniprot.org/uniprot/D1AGW5 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/526218:STERM_RS19810 ^@ http://purl.uniprot.org/uniprot/D1AGV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/526218:STERM_RS20510 ^@ http://purl.uniprot.org/uniprot/D1AGK9 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/526218:STERM_RS04670 ^@ http://purl.uniprot.org/uniprot/D1AFC9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/526218:STERM_RS18695 ^@ http://purl.uniprot.org/uniprot/D1AIV3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS08230 ^@ http://purl.uniprot.org/uniprot/D1AIE8 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/526218:STERM_RS00135 ^@ http://purl.uniprot.org/uniprot/D1AIV3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS08435 ^@ http://purl.uniprot.org/uniprot/D1AII9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS16395 ^@ http://purl.uniprot.org/uniprot/D1AQA2 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS19995 ^@ http://purl.uniprot.org/uniprot/D1AGZ2 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS11435 ^@ http://purl.uniprot.org/uniprot/D1AL37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/526218:STERM_RS02675 ^@ http://purl.uniprot.org/uniprot/D1ANU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS10730 ^@ http://purl.uniprot.org/uniprot/D1AKC0 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/526218:STERM_RS05400 ^@ http://purl.uniprot.org/uniprot/D1AFS7 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/526218:STERM_RS01395 ^@ http://purl.uniprot.org/uniprot/D1AKZ5 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/526218:STERM_RS19795 ^@ http://purl.uniprot.org/uniprot/D1AGV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/526218:STERM_RS16200 ^@ http://purl.uniprot.org/uniprot/D1APU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS13400 ^@ http://purl.uniprot.org/uniprot/D1AMJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/526218:STERM_RS18955 ^@ http://purl.uniprot.org/uniprot/D1AG31 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/526218:STERM_RS07930 ^@ http://purl.uniprot.org/uniprot/D1AI88 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS19835 ^@ http://purl.uniprot.org/uniprot/D1AGW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19680 ^@ http://purl.uniprot.org/uniprot/D1AGS9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/526218:STERM_RS15275 ^@ http://purl.uniprot.org/uniprot/D1APB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS14810 ^@ http://purl.uniprot.org/uniprot/D1ANP6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS10095 ^@ http://purl.uniprot.org/uniprot/D1AJL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/526218:STERM_RS11865 ^@ http://purl.uniprot.org/uniprot/D1ALC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/526218:STERM_RS16815 ^@ http://purl.uniprot.org/uniprot/D1AQI5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS09120 ^@ http://purl.uniprot.org/uniprot/D1AJ25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/526218:STERM_RS00970 ^@ http://purl.uniprot.org/uniprot/D1AKR0 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/526218:STERM_RS08930 ^@ http://purl.uniprot.org/uniprot/D1AIY5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/526218:STERM_RS00695 ^@ http://purl.uniprot.org/uniprot/D1AJX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07650 ^@ http://purl.uniprot.org/uniprot/D1AI34 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS03620 ^@ http://purl.uniprot.org/uniprot/D1AQ31 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS06060 ^@ http://purl.uniprot.org/uniprot/D1AH60 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/526218:STERM_RS03010 ^@ http://purl.uniprot.org/uniprot/D1AP12 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/526218:STERM_RS08200 ^@ http://purl.uniprot.org/uniprot/D1AIE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS19735 ^@ http://purl.uniprot.org/uniprot/D1AGU0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/526218:STERM_RS14800 ^@ http://purl.uniprot.org/uniprot/D1ANP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07435 ^@ http://purl.uniprot.org/uniprot/D1AHZ1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/526218:STERM_RS11450 ^@ http://purl.uniprot.org/uniprot/D1AL40 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/526218:STERM_RS18290 ^@ http://purl.uniprot.org/uniprot/D1ARP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19805 ^@ http://purl.uniprot.org/uniprot/D1AGV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/526218:STERM_RS14880 ^@ http://purl.uniprot.org/uniprot/D1ANR0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS06170 ^@ http://purl.uniprot.org/uniprot/D1AH82 ^@ Similarity ^@ Belongs to the helicase family. DnaB subfamily. http://togogenome.org/gene/526218:STERM_RS07640 ^@ http://purl.uniprot.org/uniprot/D1AI32 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS16695 ^@ http://purl.uniprot.org/uniprot/D1AQG0 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/526218:STERM_RS10475 ^@ http://purl.uniprot.org/uniprot/D1AK68 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/526218:STERM_RS19755 ^@ http://purl.uniprot.org/uniprot/D1AGU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/526218:STERM_RS17745 ^@ http://purl.uniprot.org/uniprot/D1ARE0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS14625 ^@ http://purl.uniprot.org/uniprot/D1ANL0 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/526218:STERM_RS05810 ^@ http://purl.uniprot.org/uniprot/D1AH10 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/526218:STERM_RS13445 ^@ http://purl.uniprot.org/uniprot/D1AMK7 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/526218:STERM_RS19740 ^@ http://purl.uniprot.org/uniprot/D1AGU1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/526218:STERM_RS17540 ^@ http://purl.uniprot.org/uniprot/D1ARA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18000 ^@ http://purl.uniprot.org/uniprot/D1ARJ2 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/526218:STERM_RS16045 ^@ http://purl.uniprot.org/uniprot/D1APR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS05025 ^@ http://purl.uniprot.org/uniprot/D1AFK2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/526218:STERM_RS09735 ^@ http://purl.uniprot.org/uniprot/D1AJE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/526218:STERM_RS12885 ^@ http://purl.uniprot.org/uniprot/D1AM95 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/526218:STERM_RS03155 ^@ http://purl.uniprot.org/uniprot/D1AP42 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/526218:STERM_RS00040 ^@ http://purl.uniprot.org/uniprot/D1AIT4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/526218:STERM_RS07590 ^@ http://purl.uniprot.org/uniprot/D1AI22 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS13825 ^@ http://purl.uniprot.org/uniprot/D1AN48 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/526218:STERM_RS15850 ^@ http://purl.uniprot.org/uniprot/D1APM0 ^@ Similarity ^@ Belongs to the SIS family. PHI subfamily. http://togogenome.org/gene/526218:STERM_RS04950 ^@ http://purl.uniprot.org/uniprot/D1AFI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell inner membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/526218:STERM_RS00800 ^@ http://purl.uniprot.org/uniprot/D1AJY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS11795 ^@ http://purl.uniprot.org/uniprot/D1ALA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/526218:STERM_RS03405 ^@ http://purl.uniprot.org/uniprot/D1APY7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/526218:STERM_RS13435 ^@ http://purl.uniprot.org/uniprot/D1AMK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS12110 ^@ http://purl.uniprot.org/uniprot/D1ALH2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS18425 ^@ http://purl.uniprot.org/uniprot/D1ARS3 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS14895 ^@ http://purl.uniprot.org/uniprot/D1ANR3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS11375 ^@ http://purl.uniprot.org/uniprot/D1AL25 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/526218:STERM_RS20535 ^@ http://purl.uniprot.org/uniprot/D1AGL3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS12490 ^@ http://purl.uniprot.org/uniprot/D1ALQ2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS11355 ^@ http://purl.uniprot.org/uniprot/D1AL21 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/526218:STERM_RS20380 ^@ http://purl.uniprot.org/uniprot/D1AGI7 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS15040 ^@ http://purl.uniprot.org/uniprot/D1ANU2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/526218:STERM_RS17600 ^@ http://purl.uniprot.org/uniprot/D1ARB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS14845 ^@ http://purl.uniprot.org/uniprot/D1ANQ3 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS11575 ^@ http://purl.uniprot.org/uniprot/D1AL65 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/526218:STERM_RS04690 ^@ http://purl.uniprot.org/uniprot/D1AFD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS06090 ^@ http://purl.uniprot.org/uniprot/D1AH66 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/526218:STERM_RS10795 ^@ http://purl.uniprot.org/uniprot/D1AKD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/526218:STERM_RS02690 ^@ http://purl.uniprot.org/uniprot/D1ANU8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS03235 ^@ http://purl.uniprot.org/uniprot/D1AP57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS09670 ^@ http://purl.uniprot.org/uniprot/D1AJD4 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS00275 ^@ http://purl.uniprot.org/uniprot/D1AJN6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS16275 ^@ http://purl.uniprot.org/uniprot/D1APV3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/526218:STERM_RS00555 ^@ http://purl.uniprot.org/uniprot/D1AJU4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS17070 ^@ http://purl.uniprot.org/uniprot/D1AQN5 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS22515 ^@ http://purl.uniprot.org/uniprot/D1AL15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS14755 ^@ http://purl.uniprot.org/uniprot/D1ANN6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS20320 ^@ http://purl.uniprot.org/uniprot/D1AGH4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS07695 ^@ http://purl.uniprot.org/uniprot/D1AI43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/526218:STERM_RS03065 ^@ http://purl.uniprot.org/uniprot/D1AP23 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/526218:STERM_RS12960 ^@ http://purl.uniprot.org/uniprot/D1AMB0 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/526218:STERM_RS09665 ^@ http://purl.uniprot.org/uniprot/D1AJD3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10155 ^@ http://purl.uniprot.org/uniprot/D1AK03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS14420 ^@ http://purl.uniprot.org/uniprot/D1ANH5 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/526218:STERM_RS20180 ^@ http://purl.uniprot.org/uniprot/D1AGE7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/526218:STERM_RS14905 ^@ http://purl.uniprot.org/uniprot/D1ANR5 ^@ Function ^@ Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/526218:STERM_RS08365 ^@ http://purl.uniprot.org/uniprot/D1AIH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS10740 ^@ http://purl.uniprot.org/uniprot/D1AKC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/526218:STERM_RS07560 ^@ http://purl.uniprot.org/uniprot/D1AI16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01935 ^@ http://purl.uniprot.org/uniprot/D1AM04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/526218:STERM_RS20285 ^@ http://purl.uniprot.org/uniprot/D1AGG7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS12095 ^@ http://purl.uniprot.org/uniprot/D1ALG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/526218:STERM_RS14700 ^@ http://purl.uniprot.org/uniprot/D1ANM5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS05125 ^@ http://purl.uniprot.org/uniprot/D1AFM2 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/526218:STERM_RS10090 ^@ http://purl.uniprot.org/uniprot/D1AJL8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/526218:STERM_RS17645 ^@ http://purl.uniprot.org/uniprot/D1ARC0 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/526218:STERM_RS09560 ^@ http://purl.uniprot.org/uniprot/D1AJB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/526218:STERM_RS07910 ^@ http://purl.uniprot.org/uniprot/D1AI85 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/526218:STERM_RS18690 ^@ http://purl.uniprot.org/uniprot/D1ARW7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/526218:STERM_RS08770 ^@ http://purl.uniprot.org/uniprot/D1AIQ6 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/526218:STERM_RS09015 ^@ http://purl.uniprot.org/uniprot/D1AJ04 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/526218:STERM_RS10150 ^@ http://purl.uniprot.org/uniprot/D1AK02 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/526218:STERM_RS15545 ^@ http://purl.uniprot.org/uniprot/D1APG1 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS10290 ^@ http://purl.uniprot.org/uniprot/D1AK30 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS07440 ^@ http://purl.uniprot.org/uniprot/D1AHZ2 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/526218:STERM_RS08330 ^@ http://purl.uniprot.org/uniprot/D1AIG8 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/526218:STERM_RS00080 ^@ http://purl.uniprot.org/uniprot/D1AIU2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/526218:STERM_RS01020 ^@ http://purl.uniprot.org/uniprot/D1AKS0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/526218:STERM_RS10610 ^@ http://purl.uniprot.org/uniprot/D1AK96 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/526218:STERM_RS09985 ^@ http://purl.uniprot.org/uniprot/D1AJJ7 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/526218:STERM_RS13415 ^@ http://purl.uniprot.org/uniprot/D1AMK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS15190 ^@ http://purl.uniprot.org/uniprot/D1AP93 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS20190 ^@ http://purl.uniprot.org/uniprot/D1AGE9 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/526218:STERM_RS09810 ^@ http://purl.uniprot.org/uniprot/D1AJG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17795 ^@ http://purl.uniprot.org/uniprot/D1ARF0 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/526218:STERM_RS01000 ^@ http://purl.uniprot.org/uniprot/D1AKR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/526218:STERM_RS18680 ^@ http://purl.uniprot.org/uniprot/D1ARW5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS00435 ^@ http://purl.uniprot.org/uniprot/D1AJR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/526218:STERM_RS20410 ^@ http://purl.uniprot.org/uniprot/D1AGJ3 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/526218:STERM_RS02390 ^@ http://purl.uniprot.org/uniprot/D1AMY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS19700 ^@ http://purl.uniprot.org/uniprot/D1AGT3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/526218:STERM_RS03440 ^@ http://purl.uniprot.org/uniprot/D1APZ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/526218:STERM_RS04775 ^@ http://purl.uniprot.org/uniprot/D1AFF1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS17780 ^@ http://purl.uniprot.org/uniprot/D1ARE7 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/526218:STERM_RS16785 ^@ http://purl.uniprot.org/uniprot/D1AQH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS14655 ^@ http://purl.uniprot.org/uniprot/D1ANL6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/526218:STERM_RS10340 ^@ http://purl.uniprot.org/uniprot/D1AK40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10830 ^@ http://purl.uniprot.org/uniprot/D1AKE0 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/526218:STERM_RS18880 ^@ http://purl.uniprot.org/uniprot/D1AG15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10385 ^@ http://purl.uniprot.org/uniprot/D1AK50 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/526218:STERM_RS10315 ^@ http://purl.uniprot.org/uniprot/D1AK35 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS12040 ^@ http://purl.uniprot.org/uniprot/D1ALF8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/526218:STERM_RS18130 ^@ http://purl.uniprot.org/uniprot/D1ARL4 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/526218:STERM_RS17680 ^@ http://purl.uniprot.org/uniprot/D1ARC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18960 ^@ http://purl.uniprot.org/uniprot/D1AG32 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS18150 ^@ http://purl.uniprot.org/uniprot/D1ARL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01355 ^@ http://purl.uniprot.org/uniprot/D1AKY7 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/526218:STERM_RS05030 ^@ http://purl.uniprot.org/uniprot/D1AFK3 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/526218:STERM_RS13395 ^@ http://purl.uniprot.org/uniprot/D1AMJ7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/526218:STERM_RS01750 ^@ http://purl.uniprot.org/uniprot/D1ALW7 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/526218:STERM_RS09740 ^@ http://purl.uniprot.org/uniprot/D1AJE8 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/526218:STERM_RS21215 ^@ http://purl.uniprot.org/uniprot/D1AIJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS18995 ^@ http://purl.uniprot.org/uniprot/D1AG39 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/526218:STERM_RS09230 ^@ http://purl.uniprot.org/uniprot/D1AJ48 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS14460 ^@ http://purl.uniprot.org/uniprot/D1ANI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/526218:STERM_RS18590 ^@ http://purl.uniprot.org/uniprot/D1ARU7 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/526218:STERM_RS19025 ^@ http://purl.uniprot.org/uniprot/D1AG44 ^@ Similarity ^@ Belongs to the SIS family. PHI subfamily. http://togogenome.org/gene/526218:STERM_RS10695 ^@ http://purl.uniprot.org/uniprot/D1AKB3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/526218:STERM_RS00115 ^@ http://purl.uniprot.org/uniprot/D1AIU9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/526218:STERM_RS00960 ^@ http://purl.uniprot.org/uniprot/D1AKQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS20530 ^@ http://purl.uniprot.org/uniprot/D1AGL2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/526218:STERM_RS17450 ^@ http://purl.uniprot.org/uniprot/D1AQV8 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/526218:STERM_RS14825 ^@ http://purl.uniprot.org/uniprot/D1ANP9 ^@ Similarity ^@ Belongs to the archaeal-type GPI family. http://togogenome.org/gene/526218:STERM_RS08810 ^@ http://purl.uniprot.org/uniprot/D1AIR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS10185 ^@ http://purl.uniprot.org/uniprot/D1AK09 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/526218:STERM_RS18625 ^@ http://purl.uniprot.org/uniprot/D1ARV4 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/526218:STERM_RS16510 ^@ http://purl.uniprot.org/uniprot/D1AQC5 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS17820 ^@ http://purl.uniprot.org/uniprot/D1ARF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/526218:STERM_RS13295 ^@ http://purl.uniprot.org/uniprot/D1AMH7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/526218:STERM_RS13080 ^@ http://purl.uniprot.org/uniprot/D1AMD4 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/526218:STERM_RS07795 ^@ http://purl.uniprot.org/uniprot/D1AI63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15845 ^@ http://purl.uniprot.org/uniprot/D1APL9 ^@ Similarity ^@ Belongs to the HPS/KGPDC family. HPS subfamily. http://togogenome.org/gene/526218:STERM_RS05525 ^@ http://purl.uniprot.org/uniprot/D1AFV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS08615 ^@ http://purl.uniprot.org/uniprot/D1AIM4 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/526218:STERM_RS03800 ^@ http://purl.uniprot.org/uniprot/D1AQ67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS16280 ^@ http://purl.uniprot.org/uniprot/D1APV4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/526218:STERM_RS15820 ^@ http://purl.uniprot.org/uniprot/D1APL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS20140 ^@ http://purl.uniprot.org/uniprot/D1AGD9 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/526218:STERM_RS09710 ^@ http://purl.uniprot.org/uniprot/D1AJE2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS20260 ^@ http://purl.uniprot.org/uniprot/D1AGG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01510 ^@ http://purl.uniprot.org/uniprot/D1ALR7 ^@ Similarity ^@ Belongs to the class-D beta-lactamase family. http://togogenome.org/gene/526218:STERM_RS19830 ^@ http://purl.uniprot.org/uniprot/D1AGV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/526218:STERM_RS18060 ^@ http://purl.uniprot.org/uniprot/D1ARK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/526218:STERM_RS00505 ^@ http://purl.uniprot.org/uniprot/D1AJT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/526218:STERM_RS08450 ^@ http://purl.uniprot.org/uniprot/D1AIJ2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/526218:STERM_RS01100 ^@ http://purl.uniprot.org/uniprot/D1AKT6 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/526218:STERM_RS13100 ^@ http://purl.uniprot.org/uniprot/D1AMD8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/526218:STERM_RS07140 ^@ http://purl.uniprot.org/uniprot/D1AHT4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/526218:STERM_RS17330 ^@ http://purl.uniprot.org/uniprot/D1AQT4 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/526218:STERM_RS00845 ^@ http://purl.uniprot.org/uniprot/D1AJZ4 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS20455 ^@ http://purl.uniprot.org/uniprot/D1AGK2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/526218:STERM_RS08020 ^@ http://purl.uniprot.org/uniprot/D1AIA6 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/526218:STERM_RS01030 ^@ http://purl.uniprot.org/uniprot/D1AKS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/526218:STERM_RS08280 ^@ http://purl.uniprot.org/uniprot/D1AIF8 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/526218:STERM_RS13330 ^@ http://purl.uniprot.org/uniprot/D1AMI4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS04965 ^@ http://purl.uniprot.org/uniprot/D1AFJ0 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/526218:STERM_RS07605 ^@ http://purl.uniprot.org/uniprot/D1AI25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS08750 ^@ http://purl.uniprot.org/uniprot/D1AIQ1 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS20550 ^@ http://purl.uniprot.org/uniprot/D1AGL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/526218:STERM_RS00880 ^@ http://purl.uniprot.org/uniprot/D1AKP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS08495 ^@ http://purl.uniprot.org/uniprot/D1AIK1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/526218:STERM_RS19685 ^@ http://purl.uniprot.org/uniprot/D1AGT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/526218:STERM_RS20075 ^@ http://purl.uniprot.org/uniprot/D1AGC6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS01235 ^@ http://purl.uniprot.org/uniprot/D1AKW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS09610 ^@ http://purl.uniprot.org/uniprot/D1AJC3 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/526218:STERM_RS17010 ^@ http://purl.uniprot.org/uniprot/D1AQM3 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/526218:STERM_RS08095 ^@ http://purl.uniprot.org/uniprot/D1AIC1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS12060 ^@ http://purl.uniprot.org/uniprot/D1ALG2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/526218:STERM_RS13030 ^@ http://purl.uniprot.org/uniprot/D1AMC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/526218:STERM_RS01920 ^@ http://purl.uniprot.org/uniprot/D1AM01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS13540 ^@ http://purl.uniprot.org/uniprot/D1AMM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS10205 ^@ http://purl.uniprot.org/uniprot/D1AK13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS19250 ^@ http://purl.uniprot.org/uniprot/D1AG84 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/526218:STERM_RS05395 ^@ http://purl.uniprot.org/uniprot/D1AFS6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS09945 ^@ http://purl.uniprot.org/uniprot/D1AJI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS12160 ^@ http://purl.uniprot.org/uniprot/D1ALI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/526218:STERM_RS08005 ^@ http://purl.uniprot.org/uniprot/D1AIA3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/526218:STERM_RS02485 ^@ http://purl.uniprot.org/uniprot/D1AN03 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS16205 ^@ http://purl.uniprot.org/uniprot/D1APU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS02965 ^@ http://purl.uniprot.org/uniprot/D1AP03 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/526218:STERM_RS10330 ^@ http://purl.uniprot.org/uniprot/D1AK38 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/526218:STERM_RS00490 ^@ http://purl.uniprot.org/uniprot/D1AJT1 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/526218:STERM_RS13020 ^@ http://purl.uniprot.org/uniprot/D1AMC2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/526218:STERM_RS16550 ^@ http://purl.uniprot.org/uniprot/D1AQD3 ^@ Similarity ^@ Belongs to the class-D beta-lactamase family. http://togogenome.org/gene/526218:STERM_RS10500 ^@ http://purl.uniprot.org/uniprot/D1AK73 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS01315 ^@ http://purl.uniprot.org/uniprot/D1AKX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15205 ^@ http://purl.uniprot.org/uniprot/D1AP96 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/526218:STERM_RS12895 ^@ http://purl.uniprot.org/uniprot/D1AM97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/526218:STERM_RS11115 ^@ http://purl.uniprot.org/uniprot/D1AKK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS12185 ^@ http://purl.uniprot.org/uniprot/D1ALI6 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/526218:STERM_RS09350 ^@ http://purl.uniprot.org/uniprot/D1AJ72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS13515 ^@ http://purl.uniprot.org/uniprot/D1AMM1 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS13260 ^@ http://purl.uniprot.org/uniprot/D1AMH0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/526218:STERM_RS01320 ^@ http://purl.uniprot.org/uniprot/D1AKY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/526218:STERM_RS10420 ^@ http://purl.uniprot.org/uniprot/D1AK57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10195 ^@ http://purl.uniprot.org/uniprot/D1AK11 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/526218:STERM_RS12450 ^@ http://purl.uniprot.org/uniprot/D1ALP4 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS05545 ^@ http://purl.uniprot.org/uniprot/D1AFV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/526218:STERM_RS17125 ^@ http://purl.uniprot.org/uniprot/D1AQP6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS12105 ^@ http://purl.uniprot.org/uniprot/D1ALH1 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/526218:STERM_RS00055 ^@ http://purl.uniprot.org/uniprot/D1AIT7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/526218:STERM_RS07705 ^@ http://purl.uniprot.org/uniprot/D1AI45 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/526218:STERM_RS07445 ^@ http://purl.uniprot.org/uniprot/D1AHZ3 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS15995 ^@ http://purl.uniprot.org/uniprot/D1APQ0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS02835 ^@ http://purl.uniprot.org/uniprot/D1ANX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15560 ^@ http://purl.uniprot.org/uniprot/D1APG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08195 ^@ http://purl.uniprot.org/uniprot/D1AIE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS08430 ^@ http://purl.uniprot.org/uniprot/D1AII8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15615 ^@ http://purl.uniprot.org/uniprot/D1APH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS04655 ^@ http://purl.uniprot.org/uniprot/D1AFC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS18885 ^@ http://purl.uniprot.org/uniprot/D1AG16 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/526218:STERM_RS05740 ^@ http://purl.uniprot.org/uniprot/D1AGZ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/526218:STERM_RS14510 ^@ http://purl.uniprot.org/uniprot/D1ANJ2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/526218:STERM_RS10380 ^@ http://purl.uniprot.org/uniprot/D1AK49 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS20965 ^@ http://purl.uniprot.org/uniprot/D1ALR9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/526218:STERM_RS10705 ^@ http://purl.uniprot.org/uniprot/D1AKB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS03770 ^@ http://purl.uniprot.org/uniprot/D1AQ61 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/526218:STERM_RS00590 ^@ http://purl.uniprot.org/uniprot/D1AJV0 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/526218:STERM_RS17515 ^@ http://purl.uniprot.org/uniprot/D1AQX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS16915 ^@ http://purl.uniprot.org/uniprot/D1AQK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS12100 ^@ http://purl.uniprot.org/uniprot/D1ALH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS11850 ^@ http://purl.uniprot.org/uniprot/D1ALC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS01800 ^@ http://purl.uniprot.org/uniprot/D1ALX7 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS19525 ^@ http://purl.uniprot.org/uniprot/D1AGP8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/526218:STERM_RS18070 ^@ http://purl.uniprot.org/uniprot/D1ARK2 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/526218:STERM_RS01255 ^@ http://purl.uniprot.org/uniprot/D1AKW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS04960 ^@ http://purl.uniprot.org/uniprot/D1AFI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/526218:STERM_RS04955 ^@ http://purl.uniprot.org/uniprot/D1AFI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07480 ^@ http://purl.uniprot.org/uniprot/D1AI00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS15750 ^@ http://purl.uniprot.org/uniprot/D1APK0 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/526218:STERM_RS20245 ^@ http://purl.uniprot.org/uniprot/D1AGG0 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/526218:STERM_RS13585 ^@ http://purl.uniprot.org/uniprot/D1AMN5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/526218:STERM_RS16310 ^@ http://purl.uniprot.org/uniprot/D1AQ85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/526218:STERM_RS12130 ^@ http://purl.uniprot.org/uniprot/D1ALH6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/526218:STERM_RS14970 ^@ http://purl.uniprot.org/uniprot/D1ANS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07430 ^@ http://purl.uniprot.org/uniprot/D1AHZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS19175 ^@ http://purl.uniprot.org/uniprot/D1AG69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS18225 ^@ http://purl.uniprot.org/uniprot/D1ARN3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10665 ^@ http://purl.uniprot.org/uniprot/D1AKA7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/526218:STERM_RS17730 ^@ http://purl.uniprot.org/uniprot/D1ARD7 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS11760 ^@ http://purl.uniprot.org/uniprot/D1ALA2 ^@ Similarity ^@ Belongs to the CDP-glycerol glycerophosphotransferase family. http://togogenome.org/gene/526218:STERM_RS16795 ^@ http://purl.uniprot.org/uniprot/D1AQI1 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/526218:STERM_RS15925 ^@ http://purl.uniprot.org/uniprot/D1APN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS05245 ^@ http://purl.uniprot.org/uniprot/D1AFP6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS16865 ^@ http://purl.uniprot.org/uniprot/D1AQJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS00545 ^@ http://purl.uniprot.org/uniprot/D1AJU2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS01865 ^@ http://purl.uniprot.org/uniprot/D1ALZ0 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/526218:STERM_RS05850 ^@ http://purl.uniprot.org/uniprot/D1AH18 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/526218:STERM_RS07565 ^@ http://purl.uniprot.org/uniprot/D1AI17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS12505 ^@ http://purl.uniprot.org/uniprot/D1ALQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01205 ^@ http://purl.uniprot.org/uniprot/D1AKV7 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/526218:STERM_RS10790 ^@ http://purl.uniprot.org/uniprot/D1AKD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/526218:STERM_RS07270 ^@ http://purl.uniprot.org/uniprot/D1AHV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS21840 ^@ http://purl.uniprot.org/uniprot/D1AME8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/526218:STERM_RS14915 ^@ http://purl.uniprot.org/uniprot/D1ANR7 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS02825 ^@ http://purl.uniprot.org/uniprot/D1ANX5 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS18950 ^@ http://purl.uniprot.org/uniprot/D1AG30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS03395 ^@ http://purl.uniprot.org/uniprot/D1APY5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/526218:STERM_RS14295 ^@ http://purl.uniprot.org/uniprot/D1ANE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS04695 ^@ http://purl.uniprot.org/uniprot/D1AFD4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS00515 ^@ http://purl.uniprot.org/uniprot/D1AJT6 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/526218:STERM_RS01915 ^@ http://purl.uniprot.org/uniprot/D1AM00 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10450 ^@ http://purl.uniprot.org/uniprot/D1AK63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/526218:STERM_RS19790 ^@ http://purl.uniprot.org/uniprot/D1AGV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/526218:STERM_RS13215 ^@ http://purl.uniprot.org/uniprot/D1AMG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS07145 ^@ http://purl.uniprot.org/uniprot/D1AHT5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10865 ^@ http://purl.uniprot.org/uniprot/D1AKE7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS13735 ^@ http://purl.uniprot.org/uniprot/D1AMR0 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/526218:STERM_RS20330 ^@ http://purl.uniprot.org/uniprot/D1AGH6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/526218:STERM_RS07770 ^@ http://purl.uniprot.org/uniprot/D1AI58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS13450 ^@ http://purl.uniprot.org/uniprot/D1AMK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/526218:STERM_RS11855 ^@ http://purl.uniprot.org/uniprot/D1ALC1 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/526218:STERM_RS16355 ^@ http://purl.uniprot.org/uniprot/D1AQ94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS05080 ^@ http://purl.uniprot.org/uniprot/D1AFL3 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/526218:STERM_RS19675 ^@ http://purl.uniprot.org/uniprot/D1AGS8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/526218:STERM_RS01025 ^@ http://purl.uniprot.org/uniprot/D1AKS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/526218:STERM_RS17300 ^@ http://purl.uniprot.org/uniprot/D1AQS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS18570 ^@ http://purl.uniprot.org/uniprot/D1ARU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS19285 ^@ http://purl.uniprot.org/uniprot/D1AG91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS21835 ^@ http://purl.uniprot.org/uniprot/D1AME7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS12045 ^@ http://purl.uniprot.org/uniprot/D1ALF9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/526218:STERM_RS00465 ^@ http://purl.uniprot.org/uniprot/D1AJS4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/526218:STERM_RS08825 ^@ http://purl.uniprot.org/uniprot/D1AIR7 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/526218:STERM_RS14495 ^@ http://purl.uniprot.org/uniprot/D1ANI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/526218:STERM_RS12235 ^@ http://purl.uniprot.org/uniprot/D1ALJ7 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/526218:STERM_RS01835 ^@ http://purl.uniprot.org/uniprot/D1ALY4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS05555 ^@ http://purl.uniprot.org/uniprot/D1AFV8 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/526218:STERM_RS08405 ^@ http://purl.uniprot.org/uniprot/D1AII3 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/526218:STERM_RS19770 ^@ http://purl.uniprot.org/uniprot/D1AGU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/526218:STERM_RS16465 ^@ http://purl.uniprot.org/uniprot/D1AQB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/526218:STERM_RS07535 ^@ http://purl.uniprot.org/uniprot/D1AI11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS05880 ^@ http://purl.uniprot.org/uniprot/D1AH24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS17335 ^@ http://purl.uniprot.org/uniprot/D1AQT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS02670 ^@ http://purl.uniprot.org/uniprot/D1AN42 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/526218:STERM_RS09790 ^@ http://purl.uniprot.org/uniprot/D1AJF8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS00500 ^@ http://purl.uniprot.org/uniprot/D1AJT3 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/526218:STERM_RS05865 ^@ http://purl.uniprot.org/uniprot/D1AH21 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/526218:STERM_RS01245 ^@ http://purl.uniprot.org/uniprot/D1AKW5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/526218:STERM_RS10535 ^@ http://purl.uniprot.org/uniprot/D1AK80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS16775 ^@ http://purl.uniprot.org/uniprot/D1AQH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS04995 ^@ http://purl.uniprot.org/uniprot/D1AFJ6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/526218:STERM_RS16385 ^@ http://purl.uniprot.org/uniprot/D1AQA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/526218:STERM_RS20090 ^@ http://purl.uniprot.org/uniprot/D1AGC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS17860 ^@ http://purl.uniprot.org/uniprot/D1ARG3 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/526218:STERM_RS11555 ^@ http://purl.uniprot.org/uniprot/D1AL61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/526218:STERM_RS14950 ^@ http://purl.uniprot.org/uniprot/D1ANS4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS15875 ^@ http://purl.uniprot.org/uniprot/D1APM5 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/526218:STERM_RS18175 ^@ http://purl.uniprot.org/uniprot/D1ARM3 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/526218:STERM_RS19800 ^@ http://purl.uniprot.org/uniprot/D1AGV3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/526218:STERM_RS03595 ^@ http://purl.uniprot.org/uniprot/D1AQ26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS20085 ^@ http://purl.uniprot.org/uniprot/D1AGC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS21070 ^@ http://purl.uniprot.org/uniprot/D1AR16 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/526218:STERM_RS11370 ^@ http://purl.uniprot.org/uniprot/D1AL24 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/526218:STERM_RS02460 ^@ http://purl.uniprot.org/uniprot/D1AMZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/526218:STERM_RS17265 ^@ http://purl.uniprot.org/uniprot/D1AQS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS20210 ^@ http://purl.uniprot.org/uniprot/D1AGF3 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/526218:STERM_RS02860 ^@ http://purl.uniprot.org/uniprot/D1ANY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/526218:STERM_RS18105 ^@ http://purl.uniprot.org/uniprot/D1ARK9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/526218:STERM_RS19745 ^@ http://purl.uniprot.org/uniprot/D1AGU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/526218:STERM_RS18605 ^@ http://purl.uniprot.org/uniprot/D1ARV0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/526218:STERM_RS21025 ^@ http://purl.uniprot.org/uniprot/D1ANW9 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS11430 ^@ http://purl.uniprot.org/uniprot/D1AL36 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/526218:STERM_RS10645 ^@ http://purl.uniprot.org/uniprot/D1AKA3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS09990 ^@ http://purl.uniprot.org/uniprot/D1AJJ8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS18670 ^@ http://purl.uniprot.org/uniprot/D1ARW3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS15790 ^@ http://purl.uniprot.org/uniprot/D1APK8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS18780 ^@ http://purl.uniprot.org/uniprot/D1AFZ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rhamnose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the interconversion of L-rhamnose and L-rhamnulose.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS15855 ^@ http://purl.uniprot.org/uniprot/D1APM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17640 ^@ http://purl.uniprot.org/uniprot/D1ARB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS00180 ^@ http://purl.uniprot.org/uniprot/D1AIW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS15815 ^@ http://purl.uniprot.org/uniprot/D1APL3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS15350 ^@ http://purl.uniprot.org/uniprot/D1APC5 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/526218:STERM_RS07940 ^@ http://purl.uniprot.org/uniprot/D1AI90 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/526218:STERM_RS03760 ^@ http://purl.uniprot.org/uniprot/D1AQ59 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/526218:STERM_RS18595 ^@ http://purl.uniprot.org/uniprot/D1ARU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS01250 ^@ http://purl.uniprot.org/uniprot/D1AKW6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS08885 ^@ http://purl.uniprot.org/uniprot/D1AIX6 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/526218:STERM_RS19785 ^@ http://purl.uniprot.org/uniprot/D1AGV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS11875 ^@ http://purl.uniprot.org/uniprot/D1ALC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/526218:STERM_RS18065 ^@ http://purl.uniprot.org/uniprot/D1ARK1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/526218:STERM_RS16445 ^@ http://purl.uniprot.org/uniprot/D1AQB2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10050 ^@ http://purl.uniprot.org/uniprot/D1AJL0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/526218:STERM_RS04805 ^@ http://purl.uniprot.org/uniprot/D1AFF7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/526218:STERM_RS20325 ^@ http://purl.uniprot.org/uniprot/D1AGH5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/526218:STERM_RS06420 ^@ http://purl.uniprot.org/uniprot/D1AHD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS11155 ^@ http://purl.uniprot.org/uniprot/D1AKK8 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10775 ^@ http://purl.uniprot.org/uniprot/D1AKC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/526218:STERM_RS16060 ^@ http://purl.uniprot.org/uniprot/D1APR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS05610 ^@ http://purl.uniprot.org/uniprot/D1AFW9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/526218:STERM_RS14850 ^@ http://purl.uniprot.org/uniprot/D1ANQ4 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/526218:STERM_RS17935 ^@ http://purl.uniprot.org/uniprot/D1ARH9 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/526218:STERM_RS03130 ^@ http://purl.uniprot.org/uniprot/D1AP36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/526218:STERM_RS00730 ^@ http://purl.uniprot.org/uniprot/D1AJX7 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/526218:STERM_RS09615 ^@ http://purl.uniprot.org/uniprot/D1AJC4 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/526218:STERM_RS00840 ^@ http://purl.uniprot.org/uniprot/D1AJZ3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/526218:STERM_RS15235 ^@ http://purl.uniprot.org/uniprot/D1APA2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS08465 ^@ http://purl.uniprot.org/uniprot/D1AIJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS15070 ^@ http://purl.uniprot.org/uniprot/D1AP68 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/526218:STERM_RS00270 ^@ http://purl.uniprot.org/uniprot/D1AJN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS05440 ^@ http://purl.uniprot.org/uniprot/D1AFT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/526218:STERM_RS10675 ^@ http://purl.uniprot.org/uniprot/D1AKA9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/526218:STERM_RS04685 ^@ http://purl.uniprot.org/uniprot/D1AFD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS08730 ^@ http://purl.uniprot.org/uniprot/D1AIP7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/526218:STERM_RS02840 ^@ http://purl.uniprot.org/uniprot/D1ANX8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/526218:STERM_RS01070 ^@ http://purl.uniprot.org/uniprot/D1AKT0 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/526218:STERM_RS18075 ^@ http://purl.uniprot.org/uniprot/D1ARK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS18100 ^@ http://purl.uniprot.org/uniprot/D1ARK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS14875 ^@ http://purl.uniprot.org/uniprot/D1ANQ9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS01525 ^@ http://purl.uniprot.org/uniprot/D1ALS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS19690 ^@ http://purl.uniprot.org/uniprot/D1AGT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/526218:STERM_RS11545 ^@ http://purl.uniprot.org/uniprot/D1AL59 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/526218:STERM_RS09605 ^@ http://purl.uniprot.org/uniprot/D1AJC2 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/526218:STERM_RS11380 ^@ http://purl.uniprot.org/uniprot/D1AL26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/526218:STERM_RS22410 ^@ http://purl.uniprot.org/uniprot/D1AQI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS13310 ^@ http://purl.uniprot.org/uniprot/D1AMI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Membrane http://togogenome.org/gene/526218:STERM_RS19765 ^@ http://purl.uniprot.org/uniprot/D1AGU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/526218:STERM_RS09870 ^@ http://purl.uniprot.org/uniprot/D1AJH4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/526218:STERM_RS13140 ^@ http://purl.uniprot.org/uniprot/D1AME6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS09570 ^@ http://purl.uniprot.org/uniprot/D1AJB5 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/526218:STERM_RS00940 ^@ http://purl.uniprot.org/uniprot/D1AKQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS11790 ^@ http://purl.uniprot.org/uniprot/D1ALA8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/526218:STERM_RS03750 ^@ http://purl.uniprot.org/uniprot/D1AQ57 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/526218:STERM_RS00460 ^@ http://purl.uniprot.org/uniprot/D1AJS3 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/526218:STERM_RS01535 ^@ http://purl.uniprot.org/uniprot/D1ALS2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/526218:STERM_RS10125 ^@ http://purl.uniprot.org/uniprot/D1AJM5 ^@ Function ^@ Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. http://togogenome.org/gene/526218:STERM_RS05725 ^@ http://purl.uniprot.org/uniprot/D1AFZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/526218:STERM_RS19750 ^@ http://purl.uniprot.org/uniprot/D1AGU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/526218:STERM_RS14475 ^@ http://purl.uniprot.org/uniprot/D1ANI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/526218:STERM_RS00745 ^@ http://purl.uniprot.org/uniprot/D1AJY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS06070 ^@ http://purl.uniprot.org/uniprot/D1AH62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/526218:STERM_RS01130 ^@ http://purl.uniprot.org/uniprot/D1AKU2 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/526218:STERM_RS01760 ^@ http://purl.uniprot.org/uniprot/D1ALW9 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/526218:STERM_RS05885 ^@ http://purl.uniprot.org/uniprot/D1AH25 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS12270 ^@ http://purl.uniprot.org/uniprot/D1ALK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/526218:STERM_RS11750 ^@ http://purl.uniprot.org/uniprot/D1ALA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/526218:STERM_RS19715 ^@ http://purl.uniprot.org/uniprot/D1AGT6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/526218:STERM_RS01140 ^@ http://purl.uniprot.org/uniprot/D1AKU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/526218:STERM_RS08425 ^@ http://purl.uniprot.org/uniprot/D1AII7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS10320 ^@ http://purl.uniprot.org/uniprot/D1AK36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS20790 ^@ http://purl.uniprot.org/uniprot/D1AS25 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS12025 ^@ http://purl.uniprot.org/uniprot/D1ALF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/526218:STERM_RS14140 ^@ http://purl.uniprot.org/uniprot/D1ANB3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS05615 ^@ http://purl.uniprot.org/uniprot/D1AFX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS12460 ^@ http://purl.uniprot.org/uniprot/D1ALP6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS05745 ^@ http://purl.uniprot.org/uniprot/D1AGZ7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/526218:STERM_RS01110 ^@ http://purl.uniprot.org/uniprot/D1AKT8 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/526218:STERM_RS18735 ^@ http://purl.uniprot.org/uniprot/D1ARX6 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/526218:STERM_RS09905 ^@ http://purl.uniprot.org/uniprot/D1AJI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/526218:STERM_RS11675 ^@ http://purl.uniprot.org/uniprot/D1AL85 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS03300 ^@ http://purl.uniprot.org/uniprot/D1APW6 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS02910 ^@ http://purl.uniprot.org/uniprot/D1ANZ1 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/526218:STERM_RS05800 ^@ http://purl.uniprot.org/uniprot/D1AH08 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/526218:STERM_RS14480 ^@ http://purl.uniprot.org/uniprot/D1ANI6 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/526218:STERM_RS08975 ^@ http://purl.uniprot.org/uniprot/D1AIZ4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/526218:STERM_RS18185 ^@ http://purl.uniprot.org/uniprot/D1ARM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/526218:STERM_RS10365 ^@ http://purl.uniprot.org/uniprot/D1AK46 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/526218:STERM_RS10390 ^@ http://purl.uniprot.org/uniprot/D1AK51 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/526218:STERM_RS07905 ^@ http://purl.uniprot.org/uniprot/D1AI84 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS18985 ^@ http://purl.uniprot.org/uniprot/D1AG37 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/526218:STERM_RS15050 ^@ http://purl.uniprot.org/uniprot/D1ANU4 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/526218:STERM_RS08580 ^@ http://purl.uniprot.org/uniprot/D1AIL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/526218:STERM_RS13220 ^@ http://purl.uniprot.org/uniprot/D1AMG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/526218:STERM_RS09525 ^@ http://purl.uniprot.org/uniprot/D1AJA6 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/526218:STERM_RS10545 ^@ http://purl.uniprot.org/uniprot/D1AK82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/526218:STERM_RS17260 ^@ http://purl.uniprot.org/uniprot/D1AQS1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS18135 ^@ http://purl.uniprot.org/uniprot/D1ARL5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/526218:STERM_RS10480 ^@ http://purl.uniprot.org/uniprot/D1AK69 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/526218:STERM_RS11695 ^@ http://purl.uniprot.org/uniprot/D1AL89 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/526218:STERM_RS14490 ^@ http://purl.uniprot.org/uniprot/D1ANI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/526218:STERM_RS05530 ^@ http://purl.uniprot.org/uniprot/D1AFV3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/526218:STERM_RS12850 ^@ http://purl.uniprot.org/uniprot/D1AM88 ^@ Similarity ^@ Belongs to the HPrK/P family. http://togogenome.org/gene/526218:STERM_RS07410 ^@ http://purl.uniprot.org/uniprot/D1AHY6 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS14505 ^@ http://purl.uniprot.org/uniprot/D1ANJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/526218:STERM_RS15785 ^@ http://purl.uniprot.org/uniprot/D1APK7 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS01480 ^@ http://purl.uniprot.org/uniprot/D1AL12 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/526218:STERM_RS15170 ^@ http://purl.uniprot.org/uniprot/D1AP89 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/526218:STERM_RS20445 ^@ http://purl.uniprot.org/uniprot/D1AGK0 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/526218:STERM_RS07580 ^@ http://purl.uniprot.org/uniprot/D1AI20 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/526218:STERM_RS01075 ^@ http://purl.uniprot.org/uniprot/D1AKT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS16380 ^@ http://purl.uniprot.org/uniprot/D1AQ99 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/526218:STERM_RS10510 ^@ http://purl.uniprot.org/uniprot/D1AK75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS07960 ^@ http://purl.uniprot.org/uniprot/D1AI94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS17080 ^@ http://purl.uniprot.org/uniprot/D1AQN7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS04975 ^@ http://purl.uniprot.org/uniprot/D1AFJ2 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/526218:STERM_RS19185 ^@ http://purl.uniprot.org/uniprot/D1AG71 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/526218:STERM_RS02810 ^@ http://purl.uniprot.org/uniprot/D1ANX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/526218:STERM_RS10520 ^@ http://purl.uniprot.org/uniprot/D1AK77 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS05775 ^@ http://purl.uniprot.org/uniprot/D1AH03 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/526218:STERM_RS11640 ^@ http://purl.uniprot.org/uniprot/D1AL78 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/526218:STERM_RS18160 ^@ http://purl.uniprot.org/uniprot/D1ARM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS05265 ^@ http://purl.uniprot.org/uniprot/D1AFQ0 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/526218:STERM_RS20335 ^@ http://purl.uniprot.org/uniprot/D1AGH7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/526218:STERM_RS03580 ^@ http://purl.uniprot.org/uniprot/D1AQ23 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/526218:STERM_RS21335 ^@ http://purl.uniprot.org/uniprot/D1AMA9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/526218:STERM_RS00850 ^@ http://purl.uniprot.org/uniprot/D1AJZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/526218:STERM_RS07885 ^@ http://purl.uniprot.org/uniprot/D1AI80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS11890 ^@ http://purl.uniprot.org/uniprot/D1ALC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/526218:STERM_RS16940 ^@ http://purl.uniprot.org/uniprot/D1AQL0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/526218:STERM_RS16585 ^@ http://purl.uniprot.org/uniprot/D1AQD8 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/526218:STERM_RS07630 ^@ http://purl.uniprot.org/uniprot/D1AI30 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/526218:STERM_RS06810 ^@ http://purl.uniprot.org/uniprot/D1AHL3 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. http://togogenome.org/gene/526218:STERM_RS11175 ^@ http://purl.uniprot.org/uniprot/D1AKL2 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/526218:STERM_RS02985 ^@ http://purl.uniprot.org/uniprot/D1AP07 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/526218:STERM_RS10690 ^@ http://purl.uniprot.org/uniprot/D1AKB2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/526218:STERM_RS17570 ^@ http://purl.uniprot.org/uniprot/D1ARA6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/526218:STERM_RS05120 ^@ http://purl.uniprot.org/uniprot/D1AFM1 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/526218:STERM_RS11900 ^@ http://purl.uniprot.org/uniprot/D1ALD0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/526218:STERM_RS11145 ^@ http://purl.uniprot.org/uniprot/D1AKK6 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/526218:STERM_RS14725 ^@ http://purl.uniprot.org/uniprot/D1ANN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/526218:STERM_RS10670 ^@ http://purl.uniprot.org/uniprot/D1AKA8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/526218:STERM_RS13070 ^@ http://purl.uniprot.org/uniprot/D1AMD2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/526218:STERM_RS09365 ^@ http://purl.uniprot.org/uniprot/D1AJ75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/526218:STERM_RS16700 ^@ http://purl.uniprot.org/uniprot/D1AQG1 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/526218:STERM_RS05935 ^@ http://purl.uniprot.org/uniprot/D1AH35 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/526218:STERM_RS03735 ^@ http://purl.uniprot.org/uniprot/D1AQ54 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/526218:STERM_RS03045 ^@ http://purl.uniprot.org/uniprot/D1AP19 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family.