http://togogenome.org/gene/5855:PVX_092870 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRIPT family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_002590 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSK7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS30 family. http://togogenome.org/gene/5855:PVX_080570 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYS3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. http://togogenome.org/gene/5855:PVX_099400 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV99 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6. http://togogenome.org/gene/5855:PVX_086020 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ15 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/5855:PVX_122245 ^@ http://purl.uniprot.org/uniprot/A0A1G4H476 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family. http://togogenome.org/gene/5855:PVX_082440 ^@ http://purl.uniprot.org/uniprot/A0A1G4H185 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/5855:PVX_094835 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW81 ^@ Similarity ^@ Belongs to the UQCRB/QCR7 family. http://togogenome.org/gene/5855:PVX_122740 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/5855:PVX_114195 ^@ http://purl.uniprot.org/uniprot/A0A1G4H082 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/5855:PVX_116630 ^@ http://purl.uniprot.org/uniprot/Q4PRK9 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/5855:PVX_002650 ^@ http://purl.uniprot.org/uniprot/A0A1G4H801 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/5855:PVX_079830 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYC2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/5855:PVX_118630 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 31 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/5855:PVX_089725 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/5855:PVX_095080 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWC4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/5855:PVX_124160 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5B3 ^@ Similarity ^@ Belongs to the peptidase T1B family. HslV subfamily. http://togogenome.org/gene/5855:PVX_117295 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/5855:PVX_091865 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCV5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/5855:PVX_116625 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/5855:PVX_087695 ^@ http://purl.uniprot.org/uniprot/A0A1G4GQS6 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/5855:PVX_091045 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.|||Nucleus http://togogenome.org/gene/5855:PVX_090015 ^@ http://purl.uniprot.org/uniprot/A0A1G4H941 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/5855:PVX_099540 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVC8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/5855:PVX_091095 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCF9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_002965 ^@ http://purl.uniprot.org/uniprot/A0A1G4GST5 ^@ Similarity ^@ Belongs to the CBP3 family. http://togogenome.org/gene/5855:PVX_089390 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8T0 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/5855:PVX_114490 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFA4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_094805 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/5855:PVX_089260 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/5855:PVX_119465 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_001740 ^@ http://purl.uniprot.org/uniprot/A0A1G4GU17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/5855:PVX_123597 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKR6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_117225 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/5855:PVX_085190 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRH/QCR6 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_092900 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY64 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5855:PVX_114870 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZK4 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/5855:PVX_122150 ^@ http://purl.uniprot.org/uniprot/A0A1G4H454 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/5855:PVX_002825 ^@ http://purl.uniprot.org/uniprot/A0A1G4H843 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/5855:PVX_117420 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHB0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL27 family. http://togogenome.org/gene/5855:PVX_100905 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5M9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/5855:PVX_089970 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTW1 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/5855:PVX_083030 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0V5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/5855:PVX_003650 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/5855:PVX_114245 ^@ http://purl.uniprot.org/uniprot/A0A564ZXB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCR10/QCR9 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_118520 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Membrane http://togogenome.org/gene/5855:PVX_098855 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the plant tobamovirus multiplication TOM1 protein family.|||Membrane http://togogenome.org/gene/5855:PVX_092805 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY47 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS21 family. http://togogenome.org/gene/5855:PVX_113535 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYG1 (TC 2.A.94) family.|||Membrane http://togogenome.org/gene/5855:PVX_092120 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD19 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/5855:PVX_100550 ^@ http://purl.uniprot.org/uniprot/A0A565A4K6 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/5855:PVX_115205 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_094550 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW21 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/5855:PVX_122075 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJT0 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/5855:PVX_123010 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4T8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_091925 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD66 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/5855:PVX_080210 ^@ http://purl.uniprot.org/uniprot/A0A564ZVX2 ^@ Similarity ^@ Belongs to the CDC73 family. http://togogenome.org/gene/5855:PVX_117605 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Z2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/5855:PVX_084310 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NASP family.|||Nucleus http://togogenome.org/gene/5855:PVX_117615 ^@ http://purl.uniprot.org/uniprot/A0A1G4H221 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A22B family.|||Membrane http://togogenome.org/gene/5855:PVX_099080 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV37 ^@ Similarity ^@ Belongs to the peptidase M67A family. http://togogenome.org/gene/5855:PVX_082460 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_114910 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZK0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/5855:PVX_092270 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY06 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/5855:PVX_117755 ^@ http://purl.uniprot.org/uniprot/A0A1G4H239 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NifU family.|||Mitochondrion matrix|||Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. http://togogenome.org/gene/5855:PVX_123850 ^@ http://purl.uniprot.org/uniprot/A0A1G4H561 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5855:PVX_082790 ^@ http://purl.uniprot.org/uniprot/A0A565A087 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Homodimer. http://togogenome.org/gene/5855:PVX_118180 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHP8 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/5855:PVX_115030 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF83 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/5855:PVX_096292 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7M3 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/5855:PVX_095350 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWH2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/5855:PVX_119345 ^@ http://purl.uniprot.org/uniprot/Q962K6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/5855:PVX_088895 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT62 ^@ Similarity ^@ Belongs to the CCDC124 family. http://togogenome.org/gene/5855:PVX_096265 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7N0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/5855:PVX_100800 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5J2 ^@ Similarity|||Subunit ^@ Belongs to the ubiquitin-activating E1 family.|||Heterodimer. http://togogenome.org/gene/5855:PVX_089290 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTG1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/5855:PVX_079705 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDQ1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/5855:PVX_116830 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1L7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily. http://togogenome.org/gene/5855:PVX_085950 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/5855:PVX_091350 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCK4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/5855:PVX_119685 ^@ http://purl.uniprot.org/uniprot/A0A1G4H623 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/5855:PVX_091310 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_080365 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/5855:PVX_122950 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK66 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_118645 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2R5 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_090845 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX14 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family. http://togogenome.org/gene/5855:PVX_101035 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5P3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/5855:PVX_111380 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/5855:PVX_087160 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVM1 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/5855:PVX_002700 ^@ http://purl.uniprot.org/uniprot/A0A1G4H809 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/5855:PVX_110870 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA38 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/5855:PVX_083385 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/5855:PVX_116925 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_086095 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ48 ^@ Similarity ^@ Belongs to the VPS29 family. http://togogenome.org/gene/5855:PVX_118190 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2H6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5855:PVX_093630 ^@ http://purl.uniprot.org/uniprot/A0A1G4GR28 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5855:PVX_081675 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRM0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/5855:PVX_087790 ^@ http://purl.uniprot.org/uniprot/A0A1G4GQR0 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/5855:PVX_097865 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/5855:PVX_122080 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_113340 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Membrane http://togogenome.org/gene/5855:PVX_114795 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFD5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_079885 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYD5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_002895 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSR3 ^@ Similarity ^@ Belongs to the SRR1 family. http://togogenome.org/gene/5855:PVX_114770 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZN3 ^@ Similarity ^@ Belongs to the SF3B5 family. http://togogenome.org/gene/5855:PVX_085660 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIU8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/5855:PVX_123150 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK63 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/5855:PVX_098970 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAF4 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/5855:PVX_114150 ^@ http://purl.uniprot.org/uniprot/A0A564ZXQ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_082525 ^@ http://purl.uniprot.org/uniprot/A0A1G4H158 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/5855:PVX_123555 ^@ http://purl.uniprot.org/uniprot/A0A1G4H509 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/5855:PVX_094640 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/5855:PVX_003910 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSV9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_099415 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV86 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/5855:PVX_003675 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_113990 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/5855:PVX_092125 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXS1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_114445 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF86 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/5855:PVX_086175 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3U4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/5855:PVX_090155 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5855:PVX_084230 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI58 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/5855:PVX_099185 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV39 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_091515 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/5855:PVX_088985 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8J5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL21 family. http://togogenome.org/gene/5855:PVX_093555 ^@ http://purl.uniprot.org/uniprot/A0A1G4GR30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus http://togogenome.org/gene/5855:PVX_116615 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1D2 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/5855:PVX_115255 ^@ http://purl.uniprot.org/uniprot/A0A1G4HER1 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus http://togogenome.org/gene/5855:PVX_085270 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIS6 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/5855:PVX_091025 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/5855:PVX_081305 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.|||nucleolus http://togogenome.org/gene/5855:PVX_119290 ^@ http://purl.uniprot.org/uniprot/A0A564ZU21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_096335 ^@ http://purl.uniprot.org/uniprot/A0A1G4GS25 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/5855:PVX_090950 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX30 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/5855:PVX_081230 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6S4 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5855:PVX_122930 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJZ8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_122545 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/5855:PVX_092350 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/5855:PVX_118605 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHZ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_099525 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAZ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/5855:PVX_117300 ^@ http://purl.uniprot.org/uniprot/A0A564ZZI7 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/5855:PVX_114825 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZL0|||http://purl.uniprot.org/uniprot/Q9XZD6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.|||Cytoplasm|||May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.|||Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme, while phosphorylation at Thr-158 activates it.|||Serine/threonine-protein kinase (By similarity). Involved in the control of the cell cycle. Required for entry into S-phase and mitosis (By similarity). Probable component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). http://togogenome.org/gene/5855:PVX_084685 ^@ http://purl.uniprot.org/uniprot/A0A1G4H367 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/5855:PVX_084255 ^@ http://purl.uniprot.org/uniprot/Q710D1 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.|||mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. http://togogenome.org/gene/5855:PVX_123220 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4X7 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/5855:PVX_119720 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWN0 ^@ Similarity ^@ Belongs to the proteasome subunit S14 family. http://togogenome.org/gene/5855:PVX_116980 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/5855:PVX_091195 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESS2 family.|||Nucleus http://togogenome.org/gene/5855:PVX_123630 ^@ http://purl.uniprot.org/uniprot/A0A1G4H517 ^@ Similarity ^@ Belongs to the phosphatidylethanolamine-binding protein family. http://togogenome.org/gene/5855:PVX_100735 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/5855:PVX_085850 ^@ http://purl.uniprot.org/uniprot/A0A565A1X3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_100730 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SHMT family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_119375 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_091855 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/5855:PVX_088960 ^@ http://purl.uniprot.org/uniprot/Q2XQR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/5855:PVX_117495 ^@ http://purl.uniprot.org/uniprot/A0A1G4H210 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/5855:PVX_117170 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1R1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/5855:PVX_089275 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/5855:PVX_082780 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGG3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/5855:PVX_084235 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI68 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_092065 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXR4 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/5855:PVX_114685 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF31 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/5855:PVX_082415 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGQ0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/5855:PVX_119640 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBV5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/5855:PVX_099255 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/5855:PVX_117010 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/5855:PVX_101295 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5V6 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/5855:PVX_119425 ^@ http://purl.uniprot.org/uniprot/Q962J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRQ/QCR8 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_085665 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_117515 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/5855:PVX_082520 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGL3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_099365 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAK6 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/5855:PVX_085940 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3P6 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/5855:PVX_084870 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIL8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_092820 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDJ0 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL41 family.|||Component of the large ribosomal subunit. http://togogenome.org/gene/5855:PVX_122035 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS3/PSF3 family.|||Nucleus http://togogenome.org/gene/5855:PVX_117292 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH84 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_089955 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_117890 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHU3 ^@ Similarity ^@ Belongs to the VPS10-related sortilin family. http://togogenome.org/gene/5855:PVX_088175 ^@ http://purl.uniprot.org/uniprot/A0A1G4GQY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/5855:PVX_095195 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWE2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5855:PVX_111030 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUQ1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_080370 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/5855:PVX_092250 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXT6 ^@ Similarity ^@ Belongs to the GcvH family. http://togogenome.org/gene/5855:PVX_092025 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXQ2 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/5855:PVX_097970 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_101290 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5Z2 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/5855:PVX_089370 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/5855:PVX_117620 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Z7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/5855:PVX_114935 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZM9 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/5855:PVX_089165 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5855:PVX_092575 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDB1 ^@ Similarity ^@ Belongs to the AAA ATPase family. PCH2 subfamily. http://togogenome.org/gene/5855:PVX_115210 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZE4 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/5855:PVX_113675 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFP6 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/5855:PVX_111350 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_115310 ^@ http://purl.uniprot.org/uniprot/A0A1G4HES9 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/5855:PVX_081780 ^@ http://purl.uniprot.org/uniprot/A0A1G4H732 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_001905 ^@ http://purl.uniprot.org/uniprot/A0A1G4GU81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/5855:PVX_115395 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5855:PVX_101335 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_095285 ^@ http://purl.uniprot.org/uniprot/A0A1G4HC28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_113805 ^@ http://purl.uniprot.org/uniprot/A0A1G4H094 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/5855:PVX_082500 ^@ http://purl.uniprot.org/uniprot/A0A1G4H173 ^@ Similarity ^@ Belongs to the peptidase S26B family. http://togogenome.org/gene/5855:PVX_116795 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM10 family.|||Nucleus http://togogenome.org/gene/5855:PVX_089425 ^@ http://purl.uniprot.org/uniprot/Q2VG87 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5855:PVX_089980 ^@ http://purl.uniprot.org/uniprot/A0A1G4H958 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/5855:PVX_097645 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ85 ^@ Similarity ^@ Belongs to the DPH4 family. http://togogenome.org/gene/5855:PVX_098985 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAG3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. http://togogenome.org/gene/5855:PVX_123090 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4T6 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/5855:PVX_081375 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_092090 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD22 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/5855:PVX_089495 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/5855:PVX_003760 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/5855:PVX_089130 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTA6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anamorsin family.|||Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion intermembrane space|||Monomer.|||The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.|||The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.|||The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space. http://togogenome.org/gene/5855:PVX_094725 ^@ http://purl.uniprot.org/uniprot/A0A564ZTK8 ^@ Similarity ^@ Belongs to the proteasome inhibitor PI31 family. http://togogenome.org/gene/5855:PVX_113875 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFS2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/5855:PVX_096355 ^@ http://purl.uniprot.org/uniprot/A0A564ZRN7 ^@ Similarity ^@ Belongs to the actin family. ARP6 subfamily. http://togogenome.org/gene/5855:PVX_114710 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF91 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/5855:PVX_111300 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/5855:PVX_096080 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/5855:PVX_080245 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYP4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/5855:PVX_114830 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF35 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5855:PVX_085860 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ40 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/5855:PVX_101255 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5S4 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/5855:PVX_003655 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT10 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/5855:PVX_122605 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/5855:PVX_119270 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWW0 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/5855:PVX_089325 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8S4 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/5855:PVX_111195 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA46 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.|||Component of the EKC/KEOPS complex; the whole complex dimerizes.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/5855:PVX_084910 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIK2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/5855:PVX_098015 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/5855:PVX_080405 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYV7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/5855:PVX_091810 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/5855:PVX_082570 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/5855:PVX_085300 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIT1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_110925 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUM0 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/5855:PVX_087085 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAZ6 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/5855:PVX_096400 ^@ http://purl.uniprot.org/uniprot/A0A1G4GS20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/5855:PVX_088890 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_122715 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4I1 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/5855:PVX_101050 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5Q5 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/5855:PVX_099490 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVF6 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/5855:PVX_081645 ^@ http://purl.uniprot.org/uniprot/A0A1G4H706 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAD/OST2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_117865 ^@ http://purl.uniprot.org/uniprot/A0A1G4H240 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/5855:PVX_123620 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin heavy chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||Membrane|||coated pit http://togogenome.org/gene/5855:PVX_113585 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0B2 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/5855:PVX_123075 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/5855:PVX_003970 ^@ http://purl.uniprot.org/uniprot/A0A1G4H869 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/5855:PVX_123665 ^@ http://purl.uniprot.org/uniprot/A0A1G4H541 ^@ Function|||Similarity ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).|||Belongs to the TDD superfamily. TSR3 family. http://togogenome.org/gene/5855:PVX_117030 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH16 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/5855:PVX_092215 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD30 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/5855:PVX_090935 ^@ http://purl.uniprot.org/uniprot/O96955 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_101020 ^@ http://purl.uniprot.org/uniprot/A0A1G4HL27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC4 family.|||cytoskeleton http://togogenome.org/gene/5855:PVX_089735 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTN5 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5855:PVX_115120 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEU3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family. http://togogenome.org/gene/5855:PVX_099330 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAV2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. http://togogenome.org/gene/5855:PVX_119310 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWV5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/5855:PVX_099805 ^@ http://purl.uniprot.org/uniprot/A0A564ZSP2 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/5855:PVX_123140 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKG7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_089750 ^@ http://purl.uniprot.org/uniprot/A0A1G4H912 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/5855:PVX_111175 ^@ http://purl.uniprot.org/uniprot/O96555 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_080200 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYM1 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/5855:PVX_094665 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBE1 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/5855:PVX_099465 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV95 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_100935 ^@ http://purl.uniprot.org/uniprot/A0A1G4HL19 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_080000 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYJ5 ^@ Similarity ^@ Belongs to the TYW1 family. http://togogenome.org/gene/5855:PVX_091425 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCM3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_119795 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWL9 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/5855:PVX_101315 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/5855:PVX_100520 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus http://togogenome.org/gene/5855:PVX_003830 ^@ http://purl.uniprot.org/uniprot/Q26156 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_123435 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4Z6 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5855:PVX_090965 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX34 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/5855:PVX_119540 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWR8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/5855:PVX_088130 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6F6 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/5855:PVX_085515 ^@ http://purl.uniprot.org/uniprot/Q0ZS46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GST superfamily.|||Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).|||Homodimer. In the absence of ligands two homodimers may interact to form a tetramer. http://togogenome.org/gene/5855:PVX_116900 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH95 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/5855:PVX_080425 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_115065 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZN8 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/5855:PVX_113290 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0H2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/5855:PVX_080050 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDY5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_081655 ^@ http://purl.uniprot.org/uniprot/A0A1G4H716 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS53 family.|||Endosome membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/5855:PVX_085645 ^@ http://purl.uniprot.org/uniprot/A0A565A1T6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.|||Endoplasmic reticulum membrane|||Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.|||Probable GTP-binding protein that may be involved in cell development. http://togogenome.org/gene/5855:PVX_123375 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4V5 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/5855:PVX_113860 ^@ http://purl.uniprot.org/uniprot/A0A1G4H051 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/5855:PVX_118255 ^@ http://purl.uniprot.org/uniprot/Q968V9 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/5855:PVX_097755 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ42 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/5855:PVX_092235 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/5855:PVX_083095 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0V1 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/5855:PVX_098685 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 1 family.|||Nucleus http://togogenome.org/gene/5855:PVX_116620 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGT8 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/5855:PVX_094790 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_089705 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTR0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_117745 ^@ http://purl.uniprot.org/uniprot/A0A1G4H222 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/5855:PVX_092875 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYD0 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/5855:PVX_092600 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/5855:PVX_091640 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXI2 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/5855:PVX_097860 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ34 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/5855:PVX_098640 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUV3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/5855:PVX_003920 ^@ http://purl.uniprot.org/uniprot/A0A1G4GST3 ^@ Similarity|||Subunit ^@ Belongs to the IspF family.|||Homotrimer. http://togogenome.org/gene/5855:PVX_092585 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ferredoxin--NADP reductase type 1 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_092240 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD50 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/5855:PVX_086995 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVP6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_121970 ^@ http://purl.uniprot.org/uniprot/A0A1G4H461 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/5855:PVX_095410 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBT8 ^@ Similarity ^@ Belongs to the NUF2 family. http://togogenome.org/gene/5855:PVX_117110 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1U2 ^@ Function|||Similarity ^@ Belongs to the DNA glycosylase MPG family.|||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. http://togogenome.org/gene/5855:PVX_087980 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CRT-like transporter family.|||May regulate endogenous transporter.|||Membrane|||Vacuole membrane http://togogenome.org/gene/5855:PVX_089025 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTC4 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/5855:PVX_089235 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_100555 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKZ9 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/5855:PVX_121980 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJI3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/5855:PVX_100690 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5N3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_087035 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB15 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/5855:PVX_083160 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_095130 ^@ http://purl.uniprot.org/uniprot/A0A564ZVG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal TPase family.|||Nucleus http://togogenome.org/gene/5855:PVX_089585 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTJ3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/5855:PVX_122285 ^@ http://purl.uniprot.org/uniprot/A0A1G4H484 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/5855:PVX_117470 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/5855:PVX_082850 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0Z6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_091225 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCH3 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/5855:PVX_114645 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF63 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5855:PVX_085815 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIY1 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/5855:PVX_083355 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0Y9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_118210 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the C1D family.|||Cytoplasm|||Monomer and homodimer.|||Nucleus|||Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.|||nucleolus http://togogenome.org/gene/5855:PVX_122210 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJX5 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/5855:PVX_123305 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK96 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/5855:PVX_094365 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBC2 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/5855:PVX_003600 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/5855:PVX_085690 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3K3 ^@ Similarity ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family. http://togogenome.org/gene/5855:PVX_094400 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBB1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/5855:PVX_100850 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_090160 ^@ http://purl.uniprot.org/uniprot/A0A1G4H970 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/5855:PVX_098930 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/5855:PVX_089660 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC3 subfamily.|||Nucleus http://togogenome.org/gene/5855:PVX_094450 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP25 family.|||nucleolus http://togogenome.org/gene/5855:PVX_082995 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0Y3 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/5855:PVX_080110 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/5855:PVX_086130 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ83 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_092040 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD12 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/5855:PVX_003965 ^@ http://purl.uniprot.org/uniprot/A0A1G4H887 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_086155 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJE3 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/5855:PVX_099535 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAR7 ^@ Similarity|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Monomer. http://togogenome.org/gene/5855:PVX_090175 ^@ http://purl.uniprot.org/uniprot/A0A1G4H998 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/5855:PVX_088935 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/5855:PVX_001860 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9L6 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/5855:PVX_092410 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_082580 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGM3 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/5855:PVX_123370 ^@ http://purl.uniprot.org/uniprot/A0A1G4H501 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/5855:PVX_090865 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCJ8 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5855:PVX_090930 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_082355 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_088065 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6B1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/5855:PVX_003705 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_082615 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H3 family.|||Nucleus http://togogenome.org/gene/5855:PVX_095255 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBU5 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/5855:PVX_115300 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZC2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_117980 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2A2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.|||Cytoplasm|||Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.|||Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits. http://togogenome.org/gene/5855:PVX_114660 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFA2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_122390 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJX3 ^@ Similarity ^@ Belongs to the WD repeat SMU1 family. http://togogenome.org/gene/5855:PVX_085855 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3N9 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/5855:PVX_002915 ^@ http://purl.uniprot.org/uniprot/A0A1G4H849 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/5855:PVX_081615 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRG7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_086215 ^@ http://purl.uniprot.org/uniprot/A0A1G4H410 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/5855:PVX_086310 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_080685 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTP family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_114680 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF62 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/5855:PVX_079890 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/5855:PVX_094845 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW64 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/5855:PVX_092110 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXT3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/5855:PVX_092860 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/5855:PVX_097785 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ32 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/5855:PVX_091890 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXM2 ^@ Similarity ^@ Belongs to the Tim44 family. http://togogenome.org/gene/5855:PVX_084655 ^@ http://purl.uniprot.org/uniprot/A0A1G4H309 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/5855:PVX_081760 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRJ5 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/5855:PVX_089640 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTL5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_081650 ^@ http://purl.uniprot.org/uniprot/A0A1G4H711 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_118545 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2H5 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/5855:PVX_091405 ^@ http://purl.uniprot.org/uniprot/Q5IZD8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_097960 ^@ http://purl.uniprot.org/uniprot/A0A0B4L174 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5855:PVX_116770 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGX4 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/5855:PVX_091800 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL54 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_091970 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXU4 ^@ Function|||Similarity ^@ Belongs to the dUTPase family.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/5855:PVX_081465 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/5855:PVX_101130 ^@ http://purl.uniprot.org/uniprot/A0A565A5C3 ^@ Similarity ^@ Belongs to the FAM133 family. http://togogenome.org/gene/5855:PVX_122850 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4T2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/5855:PVX_119530 ^@ http://purl.uniprot.org/uniprot/A0A1G4HC23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/5855:PVX_110980 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA18 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_113530 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0E6 ^@ Similarity|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Homodimer. http://togogenome.org/gene/5855:PVX_118405 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2F7 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/5855:PVX_099980 ^@ http://purl.uniprot.org/uniprot/Q26194 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/5855:PVX_118325 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/5855:PVX_099250 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAK9 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/5855:PVX_088170 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_122650 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK50 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/5855:PVX_098735 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/5855:PVX_095455 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL29 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_003950 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_117390 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHA8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/5855:PVX_113315 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SDE2 family.|||Nucleus http://togogenome.org/gene/5855:PVX_099395 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/5855:PVX_082470 ^@ http://purl.uniprot.org/uniprot/A0A1G4H193 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5855:PVX_116710 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH51 ^@ Similarity ^@ Belongs to the V-ATPase G subunit family. http://togogenome.org/gene/5855:PVX_090980 ^@ http://purl.uniprot.org/uniprot/A0A1G4HC95 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/5855:PVX_113935 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFL4 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/5855:PVX_085825 ^@ http://purl.uniprot.org/uniprot/Q0KHM1 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/5855:PVX_113650 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFU1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/5855:PVX_101165 ^@ http://purl.uniprot.org/uniprot/A0A1G4HLH8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/5855:PVX_081610 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6Y1 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/5855:PVX_099560 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVB8 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/5855:PVX_098815 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA84 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/5855:PVX_114735 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/5855:PVX_122565 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/5855:PVX_085575 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIS5 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/5855:PVX_117795 ^@ http://purl.uniprot.org/uniprot/A0A1G4H244 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/5855:PVX_123210 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_117625 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_002585 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSR2 ^@ Similarity ^@ Belongs to the RAMP4 family. http://togogenome.org/gene/5855:PVX_115010 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZI1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/5855:PVX_087950 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6B2 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5855:PVX_123875 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKM2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_113600 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_114050 ^@ http://purl.uniprot.org/uniprot/A0A1G4H061 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/5855:PVX_084630 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2X4 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/5855:PVX_111045 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUL2 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/5855:PVX_095380 ^@ http://purl.uniprot.org/uniprot/A0A1G4HC46 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_100780 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5J1 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/5855:PVX_099905 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/5855:PVX_117180 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Q4 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/5855:PVX_084555 ^@ http://purl.uniprot.org/uniprot/A0A565A0C3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_090000 ^@ http://purl.uniprot.org/uniprot/A0A1G4H952 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5855:PVX_117760 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHH2 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/5855:PVX_092275 ^@ http://purl.uniprot.org/uniprot/O61130 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apicomplexan parasites AMA1 family.|||Membrane http://togogenome.org/gene/5855:PVX_113465 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/5855:PVX_122430 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJR8 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/5855:PVX_095015 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cell membrane|||Cell surface|||Membrane|||Nucleus|||Vacuole|||cytoskeleton http://togogenome.org/gene/5855:PVX_114280 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFA9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_090050 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/5855:PVX_117435 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1V6 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/5855:PVX_111095 ^@ http://purl.uniprot.org/uniprot/A0A1G4HA67 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/5855:PVX_088230 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6I0 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/5855:PVX_122045 ^@ http://purl.uniprot.org/uniprot/A0A1G4H483 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/5855:PVX_114705 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/5855:PVX_084900 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF-assemblin family.|||cytoskeleton http://togogenome.org/gene/5855:PVX_084765 ^@ http://purl.uniprot.org/uniprot/A0A1G4H304 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_123450 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKD4 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/5855:PVX_084225 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_094375 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB85 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/5855:PVX_097760 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ58 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/5855:PVX_084920 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIF1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/5855:PVX_124100 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_098600 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/5855:PVX_084615 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIE1 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/5855:PVX_083465 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/5855:PVX_093605 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6K2 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-2B subfamily. http://togogenome.org/gene/5855:PVX_090975 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCC9 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/5855:PVX_114240 ^@ http://purl.uniprot.org/uniprot/A0A564ZY82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/5855:PVX_095000 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBN2 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/5855:PVX_117055 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH36 ^@ Similarity ^@ Belongs to the TLS1 family. http://togogenome.org/gene/5855:PVX_002830 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSW0 ^@ Similarity ^@ Belongs to the WD repeat SEC31 family. http://togogenome.org/gene/5855:PVX_082895 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_086075 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3S2 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/5855:PVX_091090 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DTD family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_001835 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9I1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/5855:PVX_101425 ^@ http://purl.uniprot.org/uniprot/A0A1G4HLE2 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/5855:PVX_122065 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJN3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/5855:PVX_096340 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7L1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/5855:PVX_117000 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH28 ^@ Similarity ^@ Belongs to the PNO1 family. http://togogenome.org/gene/5855:PVX_099675 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RRP8 family.|||Probable methyltransferase required to silence rDNA.|||nucleolus http://togogenome.org/gene/5855:PVX_111340 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUF1 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/5855:PVX_003885 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSV4 ^@ Similarity ^@ Belongs to the RRF family. http://togogenome.org/gene/5855:PVX_117440 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHB8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/5855:PVX_123270 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4U5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/5855:PVX_111555 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9M4 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/5855:PVX_081705 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRK7 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/5855:PVX_082515 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Membrane http://togogenome.org/gene/5855:PVX_085830 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_116950 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1K1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_117565 ^@ http://purl.uniprot.org/uniprot/Q6J153 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_085750 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3L9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_118430 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2E9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/5855:PVX_119335 ^@ http://purl.uniprot.org/uniprot/Q962K8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/5855:PVX_079880 ^@ http://purl.uniprot.org/uniprot/A0A564ZVQ6 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/5855:PVX_089560 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTK2 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/5855:PVX_088220 ^@ http://purl.uniprot.org/uniprot/A0A564ZN85 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/5855:PVX_122395 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4A9 ^@ Similarity|||Subunit ^@ Belongs to the ATPase gamma chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. http://togogenome.org/gene/5855:PVX_082840 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGG9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/5855:PVX_085225 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ14 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/5855:PVX_087120 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBA9 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/5855:PVX_090145 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/5855:PVX_114530 ^@ http://purl.uniprot.org/uniprot/A0A1G4H007 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_119800 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_119295 ^@ http://purl.uniprot.org/uniprot/A0A1G4HC65 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/5855:PVX_084345 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5855:PVX_084855 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIE6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase family.|||Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|||Homodimer. http://togogenome.org/gene/5855:PVX_114700 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.|||Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.|||nucleolus http://togogenome.org/gene/5855:PVX_089670 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_091145 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXB0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/5855:PVX_091525 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCL4 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/5855:PVX_089085 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8N5 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/5855:PVX_114210 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP68 family.|||Cytoplasm|||nucleolus http://togogenome.org/gene/5855:PVX_117360 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1W6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_099660 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVE1 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase ATAT1 family.|||Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. http://togogenome.org/gene/5855:PVX_118620 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2K1 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/5855:PVX_095190 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_119475 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWS3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/5855:PVX_085275 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_123135 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/5855:PVX_117530 ^@ http://purl.uniprot.org/uniprot/A0A564ZZB6 ^@ Similarity ^@ Belongs to the EXO5 family. http://togogenome.org/gene/5855:PVX_079780 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE02 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_123905 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKY2 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/5855:PVX_111225 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Nucleus http://togogenome.org/gene/5855:PVX_111430 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/5855:PVX_101455 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5X4 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/5855:PVX_087075 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVP4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/5855:PVX_113665 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFZ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_095175 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_094840 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_095400 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/5855:PVX_087935 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6E8 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/5855:PVX_122310 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJX9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. http://togogenome.org/gene/5855:PVX_122330 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJM7 ^@ Similarity ^@ Belongs to the ATPase delta chain family. http://togogenome.org/gene/5855:PVX_081450 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6W4 ^@ Similarity ^@ Belongs to the TSR2 family. http://togogenome.org/gene/5855:PVX_115235 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEU9 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/5855:PVX_082595 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/5855:PVX_122460 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJS4 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/5855:PVX_086230 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJA1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/5855:PVX_082820 ^@ http://purl.uniprot.org/uniprot/A0A1G4H152 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/5855:PVX_114505 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZR7 ^@ Similarity ^@ Belongs to the PTPS family. http://togogenome.org/gene/5855:PVX_079840 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/5855:PVX_096345 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7L6 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/5855:PVX_091415 ^@ http://purl.uniprot.org/uniprot/Q6J131 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_099375 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVA5 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/5855:PVX_091850 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/5855:PVX_094985 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBP1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/5855:PVX_099160 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_086005 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3R4 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/5855:PVX_114420 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFF0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/5855:PVX_084820 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIK9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_091545 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXK7 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5855:PVX_095360 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS2/PSF2 family.|||Nucleus http://togogenome.org/gene/5855:PVX_113350 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Mitochondrion matrix http://togogenome.org/gene/5855:PVX_080380 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/5855:PVX_123960 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/5855:PVX_086065 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus http://togogenome.org/gene/5855:PVX_124170 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5E9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_101090 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5Q9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_002605 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSJ3 ^@ Similarity ^@ Belongs to the SNW family. http://togogenome.org/gene/5855:PVX_085625 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3J6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/5855:PVX_083195 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/5855:PVX_123080 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK98 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. http://togogenome.org/gene/5855:PVX_117380 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/5855:PVX_083330 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP52 family.|||Cytoplasm|||flagellum http://togogenome.org/gene/5855:PVX_123445 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4X8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_091540 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCP7 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/5855:PVX_117985 ^@ http://purl.uniprot.org/uniprot/A0A1G4H261 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_114625 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF69 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5855:PVX_087090 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB34 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/5855:PVX_115340 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/5855:PVX_119480 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWS2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/5855:PVX_094750 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBH7 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/5855:PVX_085330 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/5855:PVX_091440 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXI4 ^@ Similarity ^@ Belongs to the glutaminase PdxT/SNO family. http://togogenome.org/gene/5855:PVX_114865 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_114555 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZX1 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/5855:PVX_096405 ^@ http://purl.uniprot.org/uniprot/A0A1G4GS24 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/5855:PVX_119470 ^@ http://purl.uniprot.org/uniprot/A0A564ZU34 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/5855:PVX_116705 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA40 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_114895 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZJ5 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/5855:PVX_113375 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_119355 ^@ http://purl.uniprot.org/uniprot/D3JYX6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the plasmodium circumsporozoite protein family.|||Cell membrane|||Cytoplasm|||Essential sporozoite protein (By similarity). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (By similarity). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.|||Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.|||In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.|||Membrane|||The GPI-anchor is essential for cell membrane localization and for sporozoite formation inside the oocyst.|||The N-terminus is involved in the initial binding to heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes. The N-terminus masks the TSP type-1 (TSR) domain which maintains the sporozoites in a migratory state, enabling them to complete their journey to the salivary gland in the mosquito vector and then to the host liver. The unmasking of the TSP type-1 (TSR) domain when the sporozoite interacts with the host hepatocyte also protects sporozoites from host antibodies.|||The TSP type-1 (TSR) domain is required for sporozoite development and invasion. CSP has two conformational states, an adhesive conformation in which the TSP type-1 (TSR) domain is exposed and a nonadhesive conformation in which the TSR is masked by the N-terminus. TSR-exposed conformation occurs during sporozoite development in the oocyst in the mosquito vector and during host hepatocyte invasion. TSR-masked conformation occurs during sporozoite migration through the hemolymph to salivary glands in the mosquito vector and in the host dermis. http://togogenome.org/gene/5855:PVX_092770 ^@ http://purl.uniprot.org/uniprot/A0A564ZVE4 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/5855:PVX_123000 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_089730 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM NCBP2 family.|||Nucleus http://togogenome.org/gene/5855:PVX_086990 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB16 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/5855:PVX_115200 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_114675 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF60 ^@ Similarity ^@ Belongs to the MGR2 family. http://togogenome.org/gene/5855:PVX_110895 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/5855:PVX_099895 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB80 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/5855:PVX_095270 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWF5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/5855:PVX_123570 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKK0 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/5855:PVX_095005 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWA7 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/5855:PVX_001885 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9U5 ^@ Similarity ^@ Belongs to the Iojap/RsfS family. http://togogenome.org/gene/5855:PVX_097745 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEE9 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/5855:PVX_003935 ^@ http://purl.uniprot.org/uniprot/A0A1G4GST6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_080155 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDW5 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/5855:PVX_095390 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWI3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/5855:PVX_081315 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6U7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||cytoskeleton http://togogenome.org/gene/5855:PVX_092520 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD90 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.|||Cytoplasm http://togogenome.org/gene/5855:PVX_122575 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK53 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_089280 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTH8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/5855:PVX_002685 ^@ http://purl.uniprot.org/uniprot/A0A1G4GST0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/5855:PVX_113820 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFL7 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/5855:PVX_091410 ^@ http://purl.uniprot.org/uniprot/Q7Z0B2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_118145 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHP3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/5855:PVX_094720 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_087810 ^@ http://purl.uniprot.org/uniprot/A0A1G4H668 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/5855:PVX_003845 ^@ http://purl.uniprot.org/uniprot/Q26153 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_117275 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH70 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/5855:PVX_123820 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5855:PVX_084745 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIJ3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. http://togogenome.org/gene/5855:PVX_083470 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0P8 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/5855:PVX_118580 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_080490 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_091380 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXB7 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/5855:PVX_122410 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK13 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_117025 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Q3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_002575 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the activator 1 large subunit family.|||Nucleus http://togogenome.org/gene/5855:PVX_089570 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8W6 ^@ Similarity ^@ Belongs to the RecA family. DMC1 subfamily. http://togogenome.org/gene/5855:PVX_095120 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_096360 ^@ http://purl.uniprot.org/uniprot/A0A1G4H7S6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_002675 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/5855:PVX_084205 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/5855:PVX_122675 ^@ http://purl.uniprot.org/uniprot/A0A565A2D5 ^@ Function|||Similarity|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex. http://togogenome.org/gene/5855:PVX_099695 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAU4 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/5855:PVX_091100 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/5855:PVX_086955 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_089515 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNUT3 family.|||May play a role in mRNA splicing.|||Nucleus|||Part of a tri-snRNP complex. http://togogenome.org/gene/5855:PVX_092245 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/5855:PVX_118395 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/5855:PVX_092675 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY87 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/5855:PVX_113740 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFM1 ^@ Similarity ^@ Belongs to the LSM12 family. http://togogenome.org/gene/5855:PVX_123845 ^@ http://purl.uniprot.org/uniprot/A0A1G4H564 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/5855:PVX_083260 ^@ http://purl.uniprot.org/uniprot/A0A1G4H108 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/5855:PVX_091960 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/5855:PVX_084760 ^@ http://purl.uniprot.org/uniprot/A0A1G4H357 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/5855:PVX_002640 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSK0 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/5855:PVX_119545 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/5855:PVX_083400 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0N9 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_123475 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_114120 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFF7 ^@ Similarity ^@ Belongs to the SF3A2 family. http://togogenome.org/gene/5855:PVX_111100 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9X5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/5855:PVX_111580 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUC1 ^@ Similarity ^@ Belongs to the phospholipid scramblase family. http://togogenome.org/gene/5855:PVX_118465 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHV7 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/5855:PVX_082965 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0Z7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/5855:PVX_084735 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIR4 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/5855:PVX_114355 ^@ http://purl.uniprot.org/uniprot/A0A564ZX89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/5855:PVX_101420 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5X1 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/5855:PVX_082970 ^@ http://purl.uniprot.org/uniprot/A0A1G4H121 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/5855:PVX_080400 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYQ6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/5855:PVX_085735 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ80 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/5855:PVX_003880 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSX6 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/5855:PVX_092440 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD54 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. http://togogenome.org/gene/5855:PVX_002950 ^@ http://purl.uniprot.org/uniprot/A0A1G4H847 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG14 family.|||Membrane|||Nucleus membrane http://togogenome.org/gene/5855:PVX_085155 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_085385 ^@ http://purl.uniprot.org/uniprot/A0A565A0U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/5855:PVX_081425 ^@ http://purl.uniprot.org/uniprot/A0A1X8VG02 ^@ Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. http://togogenome.org/gene/5855:PVX_091670 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCR4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/5855:PVX_116600 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Mitochondrion outer membrane http://togogenome.org/gene/5855:PVX_085020 ^@ http://purl.uniprot.org/uniprot/A0A1G4H363 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG5 family.|||Conjugated with ATG12.|||Involved in autophagic vesicle formation.|||Preautophagosomal structure membrane http://togogenome.org/gene/5855:PVX_114665 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB4 family.|||Nucleus http://togogenome.org/gene/5855:PVX_117925 ^@ http://purl.uniprot.org/uniprot/A0A1G4H290 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/5855:PVX_117395 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Z3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/5855:PVX_101080 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5W2 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/5855:PVX_098670 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/5855:PVX_002850 ^@ http://purl.uniprot.org/uniprot/A0A1G4H844 ^@ Similarity ^@ Belongs to the FAM136 family. http://togogenome.org/gene/5855:PVX_114020 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFH7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_116715 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGV7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/5855:PVX_096090 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDR2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/5855:PVX_095480 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWK4 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/5855:PVX_123495 ^@ http://purl.uniprot.org/uniprot/A0A1G4H555 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_122405 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4C1 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/5855:PVX_113775 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFM7 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5855:PVX_002955 ^@ http://purl.uniprot.org/uniprot/A0A564ZQP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_099545 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVD0 ^@ Similarity ^@ Belongs to the PRP18 family. http://togogenome.org/gene/5855:PVX_123815 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCC1 family.|||Membrane http://togogenome.org/gene/5855:PVX_117635 ^@ http://purl.uniprot.org/uniprot/A0A1G4H200 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/5855:PVX_119610 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBZ1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. http://togogenome.org/gene/5855:PVX_092765 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_098665 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAG8 ^@ Similarity ^@ Belongs to the SPCS3 family. http://togogenome.org/gene/5855:PVX_084895 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIU2 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/5855:PVX_098830 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAB2 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/5855:PVX_114790 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_085095 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIY3 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/5855:PVX_087095 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the profilin family.|||Binds actin.|||Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton.|||cytoskeleton http://togogenome.org/gene/5855:PVX_122425 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJV9 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/5855:PVX_099025 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding elongation factor family. LepA subfamily.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Mitochondrion inner membrane|||Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. http://togogenome.org/gene/5855:PVX_083210 ^@ http://purl.uniprot.org/uniprot/A0A1G4H119 ^@ Similarity ^@ Belongs to the MOG1 family. http://togogenome.org/gene/5855:PVX_085380 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_114360 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/5855:PVX_092735 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY51 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/5855:PVX_083125 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||apicoplast http://togogenome.org/gene/5855:PVX_092310 ^@ http://purl.uniprot.org/uniprot/A0A1G4HD23 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5855:PVX_003800 ^@ http://purl.uniprot.org/uniprot/A0A0E4B2A4 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/5855:PVX_095325 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBS0 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/5855:PVX_110990 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUN0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/5855:PVX_123635 ^@ http://purl.uniprot.org/uniprot/A0A1G4H526 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/5855:PVX_092775 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYA3 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/5855:PVX_092715 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDA0 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/5855:PVX_116575 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH15 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_117750 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS11 family.|||chloroplast http://togogenome.org/gene/5855:PVX_080285 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/5855:PVX_111325 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9V3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/5855:PVX_119275 ^@ http://purl.uniprot.org/uniprot/Q962M0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. http://togogenome.org/gene/5855:PVX_084990 ^@ http://purl.uniprot.org/uniprot/A0A565A1G5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/5855:PVX_118420 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSRP1 family.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Nucleus http://togogenome.org/gene/5855:PVX_094660 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBG6 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5855:PVX_099315 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV65 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/5855:PVX_122885 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4M6 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/5855:PVX_097915 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZ29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/5855:PVX_092115 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXS5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/5855:PVX_087945 ^@ http://purl.uniprot.org/uniprot/A0A1G4H686 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/5855:PVX_113855 ^@ http://purl.uniprot.org/uniprot/A0A1G4H084 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_114670 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZN6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/5855:PVX_113415 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/5855:PVX_080675 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEK0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/5855:PVX_114475 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZS6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_080120 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_114315 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFC9 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/5855:PVX_114310 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZZ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/5855:PVX_114180 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFK1 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/5855:PVX_117560 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PET117 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_085565 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIT2 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/5855:PVX_118480 ^@ http://purl.uniprot.org/uniprot/A0A564ZZV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/5855:PVX_081570 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRF7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/5855:PVX_101430 ^@ http://purl.uniprot.org/uniprot/A0A1G4H641 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_117935 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2C5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/5855:PVX_118390 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2E7 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/5855:PVX_084955 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIL4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/5855:PVX_090920 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_084585 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIF8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/5855:PVX_092810 ^@ http://purl.uniprot.org/uniprot/A0A1G4GY98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/5855:PVX_080330 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_083035 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGD0 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/5855:PVX_114290 ^@ http://purl.uniprot.org/uniprot/A0A564ZY73 ^@ Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Homodimer. http://togogenome.org/gene/5855:PVX_111305 ^@ http://purl.uniprot.org/uniprot/A0A564ZRZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||nucleolus http://togogenome.org/gene/5855:PVX_118162 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHQ0 ^@ Function|||Similarity ^@ Belongs to the centrin family.|||Plays a fundamental role in microtubule organizing center structure and function. Component of the infraciliary lattice (ICL) and the ciliary basal bodies. http://togogenome.org/gene/5855:PVX_083185 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG78 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/5855:PVX_100710 ^@ http://purl.uniprot.org/uniprot/A0A1G4HL29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_003765 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8C5 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/5855:PVX_079815 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDR7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_091060 ^@ http://purl.uniprot.org/uniprot/A0A1G4GX53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pescadillo family.|||Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.|||nucleolus|||nucleoplasm http://togogenome.org/gene/5855:PVX_101475 ^@ http://purl.uniprot.org/uniprot/A0A1G4HLD3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/5855:PVX_116675 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGW0 ^@ Similarity ^@ Belongs to the BCP1 family. http://togogenome.org/gene/5855:PVX_087925 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCE family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_101040 ^@ http://purl.uniprot.org/uniprot/A0A1G4HLD5 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/5855:PVX_113595 ^@ http://purl.uniprot.org/uniprot/A0A564ZXN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_117690 ^@ http://purl.uniprot.org/uniprot/A0A1G4H208 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/5855:PVX_123825 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKK9 ^@ Function|||Subunit ^@ One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/5855:PVX_123335 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_099825 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAY5 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5855:PVX_087860 ^@ http://purl.uniprot.org/uniprot/A0A1G4H674 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/5855:PVX_119445 ^@ http://purl.uniprot.org/uniprot/A0A564ZTY9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/5855:PVX_099425 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAN7 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_099095 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAF3 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/5855:PVX_094500 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW10 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/5855:PVX_113890 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFM4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/5855:PVX_086975 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB26 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/5855:PVX_118585 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHX2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/5855:PVX_114440 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFB4 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/5855:PVX_095290 ^@ http://purl.uniprot.org/uniprot/A0A564ZTL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/5855:PVX_079715 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/5855:PVX_101200 ^@ http://purl.uniprot.org/uniprot/A0A1G4E843 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_080455 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYW4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/5855:PVX_002720 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSL1 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/5855:PVX_119490 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWS7 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/5855:PVX_101150 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5S6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/5855:PVX_085840 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJA3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/5855:PVX_080640 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEB5 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/5855:PVX_094695 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW38 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/5855:PVX_099305 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/5855:PVX_080440 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS11 family.|||chloroplast http://togogenome.org/gene/5855:PVX_101285 ^@ http://purl.uniprot.org/uniprot/A0A1G4HLI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP11 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/5855:PVX_114015 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFK0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/5855:PVX_095135 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBM6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_117325 ^@ http://purl.uniprot.org/uniprot/A0A1G4HH90 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_099700 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/5855:PVX_084100 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI52 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/5855:PVX_003955 ^@ http://purl.uniprot.org/uniprot/A0A1G4GSZ3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/5855:PVX_118495 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2G7 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/5855:PVX_090080 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTU2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/5855:PVX_087920 ^@ http://purl.uniprot.org/uniprot/A0A1G4GQT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/5855:PVX_114835 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZN4 ^@ Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). http://togogenome.org/gene/5855:PVX_099155 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/5855:PVX_095010 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWF0 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/5855:PVX_084805 ^@ http://purl.uniprot.org/uniprot/A0A1G4H317 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/5855:PVX_098835 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUY7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/5855:PVX_117775 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHG3 ^@ Similarity ^@ Belongs to the tRNA-intron endonuclease family. http://togogenome.org/gene/5855:PVX_094615 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW49 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_091895 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.|||Nucleus http://togogenome.org/gene/5855:PVX_081325 ^@ http://purl.uniprot.org/uniprot/A0A564ZPC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/5855:PVX_080135 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/5855:PVX_122155 ^@ http://purl.uniprot.org/uniprot/A0A1G4H453 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/5855:PVX_094590 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBD9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/5855:PVX_082910 ^@ http://purl.uniprot.org/uniprot/A0A1G4HGM2 ^@ Similarity ^@ Belongs to the MOZART1 family. http://togogenome.org/gene/5855:PVX_093560 ^@ http://purl.uniprot.org/uniprot/A0A1G4GR13 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. http://togogenome.org/gene/5855:PVX_096235 ^@ http://purl.uniprot.org/uniprot/A0A1G4GS61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Cytoplasm|||Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.|||Monomer. http://togogenome.org/gene/5855:PVX_101235 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_122305 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4C9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/5855:PVX_117475 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHL1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the NnrE/AIBP family.|||Binds 1 potassium ion per subunit.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_099455 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAM5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/5855:PVX_085435 ^@ http://purl.uniprot.org/uniprot/A0A1G4HIV7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/5855:PVX_089950 ^@ http://purl.uniprot.org/uniprot/A0A1G4H943 ^@ Function|||Similarity|||Subunit ^@ Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.|||Homodimer.|||In the C-terminal section; belongs to the thymidylate synthase family.|||In the N-terminal section; belongs to the dihydrofolate reductase family. http://togogenome.org/gene/5855:PVX_080515 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE53 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/5855:PVX_122710 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJX7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/5855:PVX_080140 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus http://togogenome.org/gene/5855:PVX_118505 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI66 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family.|||Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. http://togogenome.org/gene/5855:PVX_118315 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2F6 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/5855:PVX_086325 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3X6 ^@ Similarity ^@ Belongs to the pseudouridine synthase Pus10 family. http://togogenome.org/gene/5855:PVX_081320 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/5855:PVX_080275 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYL4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/5855:PVX_098630 ^@ http://purl.uniprot.org/uniprot/A0A1G4GUY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5855:PVX_123735 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKF6 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/5855:PVX_100665 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/5855:PVX_123830 ^@ http://purl.uniprot.org/uniprot/A0A1G4H570 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I family. http://togogenome.org/gene/5855:PVX_113655 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/5855:PVX_122000 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJU2 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/5855:PVX_093520 ^@ http://purl.uniprot.org/uniprot/A0A1G4GR33 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_086315 ^@ http://purl.uniprot.org/uniprot/A0A1G4H429 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/5855:PVX_123405 ^@ http://purl.uniprot.org/uniprot/A0A1G4H531 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit beta family. http://togogenome.org/gene/5855:PVX_117670 ^@ http://purl.uniprot.org/uniprot/A0A1G4H206 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. http://togogenome.org/gene/5855:PVX_002615 ^@ http://purl.uniprot.org/uniprot/A0A1G4H856 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/5855:PVX_116495 ^@ http://purl.uniprot.org/uniprot/A0A1G4H1F8 ^@ Similarity ^@ Belongs to the RENT3 family. http://togogenome.org/gene/5855:PVX_124095 ^@ http://purl.uniprot.org/uniprot/D3JUU4 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/5855:PVX_115055 ^@ http://purl.uniprot.org/uniprot/A0A1G4HEU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/5855:PVX_118295 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2J6 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5855:PVX_099840 ^@ http://purl.uniprot.org/uniprot/A0A1G4GVK1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.|||Endoplasmic reticulum membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/5855:PVX_119815 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWK8 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5855:PVX_088115 ^@ http://purl.uniprot.org/uniprot/A0A1G4H6E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COPE family.|||Cytoplasm|||Membrane http://togogenome.org/gene/5855:PVX_094785 ^@ http://purl.uniprot.org/uniprot/A0A564ZTA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane|||Regulates also the sphingolipid metabolism. http://togogenome.org/gene/5855:PVX_081420 ^@ http://purl.uniprot.org/uniprot/A0A1G4GRC8 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/5855:PVX_122550 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK30 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/5855:PVX_098945 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/5855:PVX_123745 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKQ3 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/5855:PVX_095220 ^@ http://purl.uniprot.org/uniprot/A0A1G4GWE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/5855:PVX_114840 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/5855:PVX_114275 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZY9 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/5855:PVX_094435 ^@ http://purl.uniprot.org/uniprot/A0A1G4HBL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5855:PVX_096225 ^@ http://purl.uniprot.org/uniprot/A0A1G4GS63 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/5855:PVX_084165 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2Q1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/5855:PVX_085730 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJ21 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/5855:PVX_117895 ^@ http://purl.uniprot.org/uniprot/A0A1G4H255 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/5855:PVX_123030 ^@ http://purl.uniprot.org/uniprot/A0A1G4HK89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/5855:PVX_080625 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYY2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/5855:PVX_116945 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHA5 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/5855:PVX_114905 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/5855:PVX_099180 ^@ http://purl.uniprot.org/uniprot/A0A1G4HAG6 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/5855:PVX_089540 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8V9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/5855:PVX_116880 ^@ http://purl.uniprot.org/uniprot/A0A564ZYW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/5855:PVX_111330 ^@ http://purl.uniprot.org/uniprot/A0A1G4H9U4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/5855:PVX_122420 ^@ http://purl.uniprot.org/uniprot/A0A1G4H4J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Mitochondrion intermembrane space http://togogenome.org/gene/5855:PVX_114040 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0B4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/5855:PVX_122375 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJQ9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/5855:PVX_083405 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/5855:PVX_099135 ^@ http://purl.uniprot.org/uniprot/A0A1G4GV27 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/5855:PVX_083455 ^@ http://purl.uniprot.org/uniprot/A0A1G4H0X0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/5855:PVX_091180 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCG6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/5855:PVX_079800 ^@ http://purl.uniprot.org/uniprot/A0A1G4HDS2 ^@ Similarity ^@ Belongs to the TIP family. http://togogenome.org/gene/5855:PVX_083305 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/5855:PVX_080230 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||Nucleus http://togogenome.org/gene/5855:PVX_091665 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXL9 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/5855:PVX_091565 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXF5 ^@ Similarity ^@ Belongs to the MYST (SAS/MOZ) family. http://togogenome.org/gene/5855:PVX_081210 ^@ http://purl.uniprot.org/uniprot/A0A1G4GR79 ^@ Similarity ^@ Belongs to the TRIAP1/MDM35 family. http://togogenome.org/gene/5855:PVX_113325 ^@ http://purl.uniprot.org/uniprot/A0A1G4HG68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_114832 ^@ http://purl.uniprot.org/uniprot/A0A1G4HF35 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/5855:PVX_086040 ^@ http://purl.uniprot.org/uniprot/O60989 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/5855:PVX_094950 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/5855:PVX_122380 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJN6 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/5855:PVX_118565 ^@ http://purl.uniprot.org/uniprot/A0A1G4H2K4 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/5855:PVX_115070 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO1 family.|||Calcium-selective channel required to prevent calcium stores from overfilling.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/5855:PVX_115285 ^@ http://purl.uniprot.org/uniprot/A0A1G4HET3 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/5855:PVX_080655 ^@ http://purl.uniprot.org/uniprot/A0A1G4HE64 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/5855:PVX_118385 ^@ http://purl.uniprot.org/uniprot/A0A1G4HHT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/5855:PVX_088885 ^@ http://purl.uniprot.org/uniprot/A0A1G4GT53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/5855:PVX_089250 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/5855:PVX_080280 ^@ http://purl.uniprot.org/uniprot/A0A1G4GYQ4 ^@ Function|||Subcellular Location Annotation ^@ Converts protoheme IX and farnesyl diphosphate to heme O.|||Membrane http://togogenome.org/gene/5855:PVX_090195 ^@ http://purl.uniprot.org/uniprot/A0A1G4GU05 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/5855:PVX_115185 ^@ http://purl.uniprot.org/uniprot/A0A1G4GZF8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/5855:PVX_084995 ^@ http://purl.uniprot.org/uniprot/A0A1G4H371 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/5855:PVX_089625 ^@ http://purl.uniprot.org/uniprot/A0A1G4H8X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit G family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. http://togogenome.org/gene/5855:PVX_100980 ^@ http://purl.uniprot.org/uniprot/A0A1G4H5U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/5855:PVX_083235 ^@ http://purl.uniprot.org/uniprot/A0A142F2U4 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/5855:PVX_122115 ^@ http://purl.uniprot.org/uniprot/A0A1G4HJV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/5855:PVX_117095 ^@ http://purl.uniprot.org/uniprot/A0A564ZZ21 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/5855:PVX_114295 ^@ http://purl.uniprot.org/uniprot/A0A1G4HFE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BBP/SF1 family.|||Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.|||Nucleus http://togogenome.org/gene/5855:PVX_091375 ^@ http://purl.uniprot.org/uniprot/A0A1G4GXD2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. http://togogenome.org/gene/5855:PVX_091455 ^@ http://purl.uniprot.org/uniprot/A0A1G4HCP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.|||Membrane http://togogenome.org/gene/5855:PVX_089565 ^@ http://purl.uniprot.org/uniprot/A0A1G4GTM0 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/5855:PVX_087125 ^@ http://purl.uniprot.org/uniprot/A0A1G4HB18 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in spermatogenesis.|||Nucleus http://togogenome.org/gene/5855:PVX_094635 ^@ http://purl.uniprot.org/uniprot/A0A1G4GW40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/5855:PVX_084450 ^@ http://purl.uniprot.org/uniprot/A0A1G4HI79 ^@ Similarity ^@ Belongs to the acyl carrier protein (ACP) family. http://togogenome.org/gene/5855:PVX_085700 ^@ http://purl.uniprot.org/uniprot/A0A1G4H3K9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.|||Mitochondrion|||Nucleus http://togogenome.org/gene/5855:PVX_122980 ^@ http://purl.uniprot.org/uniprot/A0A1G4HKD5 ^@ Similarity ^@ Belongs to the eukaryotic ATPase epsilon family.