http://togogenome.org/gene/61651:CKW09_RS15065 ^@ http://purl.uniprot.org/uniprot/A0A240C4P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A240C1S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS18785 ^@ http://purl.uniprot.org/uniprot/A0A240C889 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A240AWY3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/61651:CKW09_RS15385 ^@ http://purl.uniprot.org/uniprot/A0A240C516 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/61651:CKW09_RS17085 ^@ http://purl.uniprot.org/uniprot/A0A240C6K6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A240C611 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A240C148 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/61651:CKW09_RS13290 ^@ http://purl.uniprot.org/uniprot/A0A240C4V8 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/61651:CKW09_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A240AG64 ^@ Function|||Similarity|||Subunit ^@ Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).|||In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.|||Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. http://togogenome.org/gene/61651:CKW09_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A240BGC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/61651:CKW09_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A240AZW9 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/61651:CKW09_RS23875 ^@ http://purl.uniprot.org/uniprot/A0A240CEC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS16090 ^@ http://purl.uniprot.org/uniprot/A0A240C662 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/61651:CKW09_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A240BMB0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/61651:CKW09_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A240C532 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S49 family.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A240BR36 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/61651:CKW09_RS14715 ^@ http://purl.uniprot.org/uniprot/A0A240C4B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A240AGM0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/61651:CKW09_RS23560 ^@ http://purl.uniprot.org/uniprot/A0A240CDZ7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS20560 ^@ http://purl.uniprot.org/uniprot/A0A240CAF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS20725 ^@ http://purl.uniprot.org/uniprot/A0A240CCQ5 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/61651:CKW09_RS20675 ^@ http://purl.uniprot.org/uniprot/A0A240CAJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A240CA51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A240A7T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A240CCD4 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the L-aspartate dehydrogenase family.|||Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.|||The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. http://togogenome.org/gene/61651:CKW09_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A240BYZ3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A240C9A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/61651:CKW09_RS22060 ^@ http://purl.uniprot.org/uniprot/A0A240CE17 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/61651:CKW09_RS20515 ^@ http://purl.uniprot.org/uniprot/A0A240CBJ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/61651:CKW09_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A240AZ84 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS21645 ^@ http://purl.uniprot.org/uniprot/A0A240CBC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22830 ^@ http://purl.uniprot.org/uniprot/A0A240CCT5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DamX family.|||Cell inner membrane|||Non-essential cell division protein.|||The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring. http://togogenome.org/gene/61651:CKW09_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A240BT50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A240AYY8 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/61651:CKW09_RS14735 ^@ http://purl.uniprot.org/uniprot/A0A240C6M7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A240ASD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/61651:CKW09_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A240BYM5 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/61651:CKW09_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A240ABA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/61651:CKW09_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A240A949 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/61651:CKW09_RS19985 ^@ http://purl.uniprot.org/uniprot/A0A240CB37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS21935 ^@ http://purl.uniprot.org/uniprot/A0A240CBY3 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A240BQR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A240AYP0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A240BQH9 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/61651:CKW09_RS20605 ^@ http://purl.uniprot.org/uniprot/A0A240CAN5 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/61651:CKW09_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A240AI59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Cell inner membrane|||Membrane|||Transports acetate. http://togogenome.org/gene/61651:CKW09_RS21590 ^@ http://purl.uniprot.org/uniprot/A0A240CCJ4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/61651:CKW09_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A240ABA0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/61651:CKW09_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A240BUR4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS22100 ^@ http://purl.uniprot.org/uniprot/A0A240CE53 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/61651:CKW09_RS23655 ^@ http://purl.uniprot.org/uniprot/A0A240CED6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/61651:CKW09_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A240APT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS20695 ^@ http://purl.uniprot.org/uniprot/A0A240CAL8 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/61651:CKW09_RS22935 ^@ http://purl.uniprot.org/uniprot/A0A240CCR7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/61651:CKW09_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A240AHM0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/61651:CKW09_RS21650 ^@ http://purl.uniprot.org/uniprot/A0A240CDQ9 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A240AT12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13315 ^@ http://purl.uniprot.org/uniprot/A0A240C2L2 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/61651:CKW09_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A240BLX8 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/61651:CKW09_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A240B2W3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS23005 ^@ http://purl.uniprot.org/uniprot/A0A240CD40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Cell membrane|||Membrane|||Rhomboid-type serine protease that catalyzes intramembrane proteolysis. http://togogenome.org/gene/61651:CKW09_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A240BTQ6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/61651:CKW09_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A240BM92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22595 ^@ http://purl.uniprot.org/uniprot/A0A240CCI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrH/TusB family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/61651:CKW09_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A240BQ46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS19855 ^@ http://purl.uniprot.org/uniprot/A0A240CA34 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS21345 ^@ http://purl.uniprot.org/uniprot/A0A240CCA7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS11765 ^@ http://purl.uniprot.org/uniprot/A0A240C099 ^@ Similarity ^@ Belongs to the UPF0482 family. http://togogenome.org/gene/61651:CKW09_RS13940 ^@ http://purl.uniprot.org/uniprot/A0A240C5R8 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/61651:CKW09_RS16950 ^@ http://purl.uniprot.org/uniprot/A0A240C6P4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/61651:CKW09_RS22590 ^@ http://purl.uniprot.org/uniprot/A0A240CCI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/61651:CKW09_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A240C9A0 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/61651:CKW09_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A240BTY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS22470 ^@ http://purl.uniprot.org/uniprot/A0A240CC70 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/61651:CKW09_RS19130 ^@ http://purl.uniprot.org/uniprot/A0A240CB91 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A240C110 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/61651:CKW09_RS23280 ^@ http://purl.uniprot.org/uniprot/A0A240CDK5 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/61651:CKW09_RS18730 ^@ http://purl.uniprot.org/uniprot/A0A240C980 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/61651:CKW09_RS21840 ^@ http://purl.uniprot.org/uniprot/A0A240CBP3 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/61651:CKW09_RS23675 ^@ http://purl.uniprot.org/uniprot/A0A240CE73 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/61651:CKW09_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A240BI91 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/61651:CKW09_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A240BZ76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21235 ^@ http://purl.uniprot.org/uniprot/A0A240CC74 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A240C1A5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/61651:CKW09_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A240ASY7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/61651:CKW09_RS23595 ^@ http://purl.uniprot.org/uniprot/A0A240CF61 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M20A family. ArgE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A240BJ30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS16935 ^@ http://purl.uniprot.org/uniprot/A0A240C708 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/61651:CKW09_RS23945 ^@ http://purl.uniprot.org/uniprot/A0A240CFP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/61651:CKW09_RS19135 ^@ http://purl.uniprot.org/uniprot/A0A240C8E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23885 ^@ http://purl.uniprot.org/uniprot/A0A240CET1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/61651:CKW09_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A240C787 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS23645 ^@ http://purl.uniprot.org/uniprot/A0A240CED4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/61651:CKW09_RS11385 ^@ http://purl.uniprot.org/uniprot/A0A240C0V9 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/61651:CKW09_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A240BLQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A240BHT2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16990 ^@ http://purl.uniprot.org/uniprot/A0A240C718 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/61651:CKW09_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A240BNV1 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/61651:CKW09_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A240B260 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/61651:CKW09_RS22615 ^@ http://purl.uniprot.org/uniprot/A0A240CCJ3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/61651:CKW09_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A240B5J9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS16055 ^@ http://purl.uniprot.org/uniprot/A0A240C7J5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS15615 ^@ http://purl.uniprot.org/uniprot/A0A240C709 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A240AZS1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/61651:CKW09_RS14045 ^@ http://purl.uniprot.org/uniprot/A0A240C2Z0 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A240BMC6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS16400 ^@ http://purl.uniprot.org/uniprot/A0A240C8J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS12970 ^@ http://purl.uniprot.org/uniprot/A0A240C1Z6 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/61651:CKW09_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A240C612 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A240C3Q3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/61651:CKW09_RS21305 ^@ http://purl.uniprot.org/uniprot/A0A240CB66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/61651:CKW09_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A240C299 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/61651:CKW09_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A240BQC3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/61651:CKW09_RS22825 ^@ http://purl.uniprot.org/uniprot/A0A240CCY7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/61651:CKW09_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A240C6T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS24000 ^@ http://purl.uniprot.org/uniprot/A0A240CEI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A240AH27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A240C714 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A240C1L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A240BKI0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS23535 ^@ http://purl.uniprot.org/uniprot/A0A240CE74 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.|||Cell outer membrane|||Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A240BIC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/61651:CKW09_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A240BSY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS19235 ^@ http://purl.uniprot.org/uniprot/A0A240C8U6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A240AIX9 ^@ Cofactor ^@ Binds 1 phosphopantetheine covalently. http://togogenome.org/gene/61651:CKW09_RS19615 ^@ http://purl.uniprot.org/uniprot/A0A240CBK6 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/61651:CKW09_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A240AWU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A240BPB4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/61651:CKW09_RS21655 ^@ http://purl.uniprot.org/uniprot/A0A240CBI3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS18270 ^@ http://purl.uniprot.org/uniprot/A0A240CA04 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/61651:CKW09_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A240BEU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/61651:CKW09_RS20280 ^@ http://purl.uniprot.org/uniprot/A0A240CCB2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A240BQ29 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/61651:CKW09_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A240C837 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/61651:CKW09_RS15585 ^@ http://purl.uniprot.org/uniprot/A0A240C4P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A240AV73 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A240AYQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.|||Cell membrane|||Homodimer.|||Membrane|||Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. http://togogenome.org/gene/61651:CKW09_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A240BSD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/61651:CKW09_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A240CAE9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A240A7I6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/61651:CKW09_RS22235 ^@ http://purl.uniprot.org/uniprot/A0A240CE85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13580 ^@ http://purl.uniprot.org/uniprot/A0A240C3F6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/61651:CKW09_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A240C0G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the rhamnose mutarotase family.|||Cytoplasm|||Homodimer.|||Involved in the anomeric conversion of L-rhamnose. http://togogenome.org/gene/61651:CKW09_RS19505 ^@ http://purl.uniprot.org/uniprot/A0A240C998 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A240C6V5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/61651:CKW09_RS14570 ^@ http://purl.uniprot.org/uniprot/A0A240C458 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. WecA subfamily.|||Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS20195 ^@ http://purl.uniprot.org/uniprot/A0A240CAI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/61651:CKW09_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A240C3T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS23255 ^@ http://purl.uniprot.org/uniprot/A0A240CDJ9 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/61651:CKW09_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A240AY46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/61651:CKW09_RS20795 ^@ http://purl.uniprot.org/uniprot/A0A240CAP8 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/61651:CKW09_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A240CAS6 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/61651:CKW09_RS21400 ^@ http://purl.uniprot.org/uniprot/A0A240CDG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).|||Membrane http://togogenome.org/gene/61651:CKW09_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A240B3P5 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/61651:CKW09_RS13325 ^@ http://purl.uniprot.org/uniprot/A0A240C4S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS22740 ^@ http://purl.uniprot.org/uniprot/A0A240CER6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/61651:CKW09_RS21610 ^@ http://purl.uniprot.org/uniprot/A0A240CBS7 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/61651:CKW09_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A240BXX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.|||Cytoplasm|||Interacts with TusE. http://togogenome.org/gene/61651:CKW09_RS15755 ^@ http://purl.uniprot.org/uniprot/A0A240C5G5 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/61651:CKW09_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A240C914 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS22510 ^@ http://purl.uniprot.org/uniprot/A0A240CDI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS22945 ^@ http://purl.uniprot.org/uniprot/A0A240CF07 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/61651:CKW09_RS10985 ^@ http://purl.uniprot.org/uniprot/A0A240BZ66 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/61651:CKW09_RS22770 ^@ http://purl.uniprot.org/uniprot/A0A240CD07 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/61651:CKW09_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A240BVM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A240C3U9 ^@ Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family. DsdA subfamily.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS16210 ^@ http://purl.uniprot.org/uniprot/A0A240C5Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A240BMD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18665 ^@ http://purl.uniprot.org/uniprot/A0A240C7X6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/61651:CKW09_RS23915 ^@ http://purl.uniprot.org/uniprot/A0A240CEJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/61651:CKW09_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A240A834 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS21215 ^@ http://purl.uniprot.org/uniprot/A0A240CB40 ^@ Similarity ^@ Belongs to the UPF0441 family. http://togogenome.org/gene/61651:CKW09_RS19800 ^@ http://purl.uniprot.org/uniprot/A0A240C9Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A240BLL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A240C537 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A240BTG2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A240AWW4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/61651:CKW09_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A240BP46 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A240C8G9 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/61651:CKW09_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A240BZ77 ^@ Function ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. http://togogenome.org/gene/61651:CKW09_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A240BUL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS15545 ^@ http://purl.uniprot.org/uniprot/A0A240C795 ^@ Similarity ^@ Belongs to the DsrB family. http://togogenome.org/gene/61651:CKW09_RS20770 ^@ http://purl.uniprot.org/uniprot/A0A240CBT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A240C1H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A240AUJ0 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS12430 ^@ http://purl.uniprot.org/uniprot/A0A240C375 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A240A9Y2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/61651:CKW09_RS10775 ^@ http://purl.uniprot.org/uniprot/A0A240BY87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A240BLM1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/61651:CKW09_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A240C1H0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/61651:CKW09_RS21490 ^@ http://purl.uniprot.org/uniprot/A0A240CBI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A240BGD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/61651:CKW09_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A240BUW3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/61651:CKW09_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A240C6X6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/61651:CKW09_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A240C724 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A240C2P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A240C2R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A240C6E0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RcsD family.|||Cell inner membrane|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.|||Interacts with RcsC and RcsB.|||Phosphorylated by RcsC. http://togogenome.org/gene/61651:CKW09_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A240C9F9 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/61651:CKW09_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A240B459 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/61651:CKW09_RS23950 ^@ http://purl.uniprot.org/uniprot/A0A240CEW0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/61651:CKW09_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A240C1C9 ^@ Similarity ^@ Belongs to the glyoxalase I family. http://togogenome.org/gene/61651:CKW09_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A240C720 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/61651:CKW09_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A240AXY1 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/61651:CKW09_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A240AZL9 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/61651:CKW09_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A240AXV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A240C8V8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/61651:CKW09_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A240AY88 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/61651:CKW09_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A240BZ94 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A240ARH2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/61651:CKW09_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A240BGU3 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/61651:CKW09_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A240A969 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A240C654 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16855 ^@ http://purl.uniprot.org/uniprot/A0A240C6G0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/61651:CKW09_RS10905 ^@ http://purl.uniprot.org/uniprot/A0A240BYZ5 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/61651:CKW09_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A240C0G9 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/61651:CKW09_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A240BPZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A240C773 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A240BH50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/61651:CKW09_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A240B0T0 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/61651:CKW09_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A240B0C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A240C5R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA gyrase inhibitor family.|||Cytoplasm|||Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.|||Interacts with DNA gyrase. http://togogenome.org/gene/61651:CKW09_RS21905 ^@ http://purl.uniprot.org/uniprot/A0A240CBX7 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/61651:CKW09_RS22130 ^@ http://purl.uniprot.org/uniprot/A0A240CC64 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/61651:CKW09_RS16735 ^@ http://purl.uniprot.org/uniprot/A0A240C8X0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/61651:CKW09_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A240BKA9 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/61651:CKW09_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A240AWQ7 ^@ Similarity ^@ Belongs to the Smp family. http://togogenome.org/gene/61651:CKW09_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A240BRT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/61651:CKW09_RS16370 ^@ http://purl.uniprot.org/uniprot/A0A240C5J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.|||Cell membrane|||Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.|||Membrane http://togogenome.org/gene/61651:CKW09_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A240ANC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdD family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/61651:CKW09_RS13460 ^@ http://purl.uniprot.org/uniprot/A0A240C2M6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS14700 ^@ http://purl.uniprot.org/uniprot/A0A240C560 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13985 ^@ http://purl.uniprot.org/uniprot/A0A240C5L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/61651:CKW09_RS20410 ^@ http://purl.uniprot.org/uniprot/A0A240CAP7 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/61651:CKW09_RS23060 ^@ http://purl.uniprot.org/uniprot/A0A240CDG5 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/61651:CKW09_RS20235 ^@ http://purl.uniprot.org/uniprot/A0A240C9Z7 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/61651:CKW09_RS13400 ^@ http://purl.uniprot.org/uniprot/A0A240C3K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS24060 ^@ http://purl.uniprot.org/uniprot/A0A240CET3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A240BG27 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/61651:CKW09_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A240AFC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23765 ^@ http://purl.uniprot.org/uniprot/A0A240CEC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/61651:CKW09_RS20110 ^@ http://purl.uniprot.org/uniprot/A0A240CA43 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/61651:CKW09_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A240BWN4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A240C2W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS14290 ^@ http://purl.uniprot.org/uniprot/A0A240C488 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/61651:CKW09_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A240BFX6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A240B4S9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A240BUQ2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A240ARQ0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/61651:CKW09_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A240C6V3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A240C3E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16810 ^@ http://purl.uniprot.org/uniprot/A0A240C8M2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A240BMR5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/61651:CKW09_RS22365 ^@ http://purl.uniprot.org/uniprot/A0A240CEC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/61651:CKW09_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A240AZA7 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/61651:CKW09_RS20955 ^@ http://purl.uniprot.org/uniprot/A0A240CAT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A240C7B2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/61651:CKW09_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A240C784 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS19705 ^@ http://purl.uniprot.org/uniprot/A0A240C9L9 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/61651:CKW09_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A240B0H1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A240BM61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/61651:CKW09_RS22715 ^@ http://purl.uniprot.org/uniprot/A0A240CEQ6 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/61651:CKW09_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A240BTW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/61651:CKW09_RS19450 ^@ http://purl.uniprot.org/uniprot/A0A240C952 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/61651:CKW09_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A240CD34 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/61651:CKW09_RS16235 ^@ http://purl.uniprot.org/uniprot/A0A240C5Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A240AZX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/61651:CKW09_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A240AJT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS13495 ^@ http://purl.uniprot.org/uniprot/A0A240C2P9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A240C811 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/61651:CKW09_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A240BM25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinone-dependent D-lactate dehydrogenase family.|||Catalyzes the oxidation of D-lactate to pyruvate.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A240B176 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/61651:CKW09_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A240C9N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A240C6V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS19295 ^@ http://purl.uniprot.org/uniprot/A0A240CB16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A240BKZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS15485 ^@ http://purl.uniprot.org/uniprot/A0A240C618 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS18185 ^@ http://purl.uniprot.org/uniprot/A0A240C8K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS04240 ^@ http://purl.uniprot.org/uniprot/A0A240AZZ9 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/61651:CKW09_RS18845 ^@ http://purl.uniprot.org/uniprot/A0A240C883 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A240CAG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS20275 ^@ http://purl.uniprot.org/uniprot/A0A240CA91 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/61651:CKW09_RS14095 ^@ http://purl.uniprot.org/uniprot/A0A240C4H9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/61651:CKW09_RS16725 ^@ http://purl.uniprot.org/uniprot/A0A240C6B2 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/61651:CKW09_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A240ADA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/61651:CKW09_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A240CCH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A240C463 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/61651:CKW09_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A240B4B0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS18645 ^@ http://purl.uniprot.org/uniprot/A0A240CA31 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A240AHD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rsd/AlgQ family.|||Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.|||Cytoplasm|||Interacts with RpoD. http://togogenome.org/gene/61651:CKW09_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A240BTY5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A240CCK4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/61651:CKW09_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A240AY66 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/61651:CKW09_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A240BMM8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS21265 ^@ http://purl.uniprot.org/uniprot/A0A240CDB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A240BRG3 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.|||Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. http://togogenome.org/gene/61651:CKW09_RS17010 ^@ http://purl.uniprot.org/uniprot/A0A240C963 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/61651:CKW09_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A240BJN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18840 ^@ http://purl.uniprot.org/uniprot/A0A240C872 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/61651:CKW09_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A240C3M3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS22775 ^@ http://purl.uniprot.org/uniprot/A0A240CCI0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/61651:CKW09_RS21105 ^@ http://purl.uniprot.org/uniprot/A0A240CC35 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/61651:CKW09_RS23555 ^@ http://purl.uniprot.org/uniprot/A0A240CDZ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A240B1D4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS23240 ^@ http://purl.uniprot.org/uniprot/A0A240CDP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A240C6N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS19535 ^@ http://purl.uniprot.org/uniprot/A0A240C9B0 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/61651:CKW09_RS14475 ^@ http://purl.uniprot.org/uniprot/A0A240C3U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A240AYI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23270 ^@ http://purl.uniprot.org/uniprot/A0A240CFP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A240BML2 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. http://togogenome.org/gene/61651:CKW09_RS18595 ^@ http://purl.uniprot.org/uniprot/A0A240CAG5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/61651:CKW09_RS20730 ^@ http://purl.uniprot.org/uniprot/A0A240CDA8 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/61651:CKW09_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A240B0U8 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/61651:CKW09_RS16860 ^@ http://purl.uniprot.org/uniprot/A0A240C6C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A240B1A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/61651:CKW09_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A240B509 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/61651:CKW09_RS22085 ^@ http://purl.uniprot.org/uniprot/A0A240CBZ0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/61651:CKW09_RS18705 ^@ http://purl.uniprot.org/uniprot/A0A240C7Z9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/61651:CKW09_RS14090 ^@ http://purl.uniprot.org/uniprot/A0A240C414 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/61651:CKW09_RS24290 ^@ http://purl.uniprot.org/uniprot/A0A240CF42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A240C8C3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A240AQ45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/61651:CKW09_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A240AR34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/61651:CKW09_RS24020 ^@ http://purl.uniprot.org/uniprot/A0A240CEJ6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/61651:CKW09_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A240BV04 ^@ Function|||Similarity ^@ Belongs to the RutC family.|||Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions. http://togogenome.org/gene/61651:CKW09_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A240C113 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/61651:CKW09_RS20685 ^@ http://purl.uniprot.org/uniprot/A0A240CAN3 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/61651:CKW09_RS23475 ^@ http://purl.uniprot.org/uniprot/A0A240CGN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A240AQ39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/61651:CKW09_RS17830 ^@ http://purl.uniprot.org/uniprot/A0A240C7A3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS23900 ^@ http://purl.uniprot.org/uniprot/A0A240CFM9 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/61651:CKW09_RS13950 ^@ http://purl.uniprot.org/uniprot/A0A240C2V4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/61651:CKW09_RS24275 ^@ http://purl.uniprot.org/uniprot/A0A240CHV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS22495 ^@ http://purl.uniprot.org/uniprot/A0A240CCD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/61651:CKW09_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A240C6Y3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/61651:CKW09_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A240C100 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A240BW65 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/61651:CKW09_RS22785 ^@ http://purl.uniprot.org/uniprot/A0A240CCX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TsgA family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A240B3L1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A240AXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21010 ^@ http://purl.uniprot.org/uniprot/A0A240CB81 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/61651:CKW09_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A240BQQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A240B1U4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A240AIT0 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis. http://togogenome.org/gene/61651:CKW09_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A240BHI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/61651:CKW09_RS22430 ^@ http://purl.uniprot.org/uniprot/A0A240CDG4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/61651:CKW09_RS23960 ^@ http://purl.uniprot.org/uniprot/A0A240CEU6 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/61651:CKW09_RS19495 ^@ http://purl.uniprot.org/uniprot/A0A240C984 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A240AQ12 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/61651:CKW09_RS19945 ^@ http://purl.uniprot.org/uniprot/A0A240CA77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.|||Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A240C5N8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A240BT52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18700 ^@ http://purl.uniprot.org/uniprot/A0A240C838 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. Interacts with IscU. http://togogenome.org/gene/61651:CKW09_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A240BR56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/61651:CKW09_RS16140 ^@ http://purl.uniprot.org/uniprot/A0A240C6R2 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/61651:CKW09_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A240BJD4 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/61651:CKW09_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A240APM6 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/61651:CKW09_RS20415 ^@ http://purl.uniprot.org/uniprot/A0A240CAB3 ^@ Function|||Similarity ^@ Belongs to the arginase family. Agmatinase subfamily.|||Catalyzes the formation of putrescine from agmatine. http://togogenome.org/gene/61651:CKW09_RS21910 ^@ http://purl.uniprot.org/uniprot/A0A240CBS2 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/61651:CKW09_RS19715 ^@ http://purl.uniprot.org/uniprot/A0A240C9K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MutH family.|||Cytoplasm|||Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. http://togogenome.org/gene/61651:CKW09_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A240ACH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A240C6Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A240BTV8 ^@ Function|||Similarity ^@ Belongs to the isochorismatase family. RutB subfamily.|||Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2. http://togogenome.org/gene/61651:CKW09_RS16870 ^@ http://purl.uniprot.org/uniprot/A0A240C638 ^@ Similarity ^@ To H.influenzae HI_0842. http://togogenome.org/gene/61651:CKW09_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A240BS26 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/61651:CKW09_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A240AYX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.|||Cell inner membrane|||Homodimer. Interacts with the regulatory subunit KefF.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/61651:CKW09_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A240AIF9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/61651:CKW09_RS22205 ^@ http://purl.uniprot.org/uniprot/A0A240CC50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A240C1L7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/61651:CKW09_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A240BRB7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/61651:CKW09_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A240BLG0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A240C5R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A240ATJ6 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/61651:CKW09_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A240AY15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS21810 ^@ http://purl.uniprot.org/uniprot/A0A240CBT3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.|||Cell membrane|||Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A240AY48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TrpR family.|||Cytoplasm|||Homodimer.|||This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. http://togogenome.org/gene/61651:CKW09_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A240AKM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS22700 ^@ http://purl.uniprot.org/uniprot/A0A240CCL8 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/61651:CKW09_RS14300 ^@ http://purl.uniprot.org/uniprot/A0A240C5L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A240AQB5 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/61651:CKW09_RS11640 ^@ http://purl.uniprot.org/uniprot/A0A240C032 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A240BGY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A240BPU0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/61651:CKW09_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A240C5D1 ^@ Function|||Similarity ^@ Belongs to the GlgS family.|||Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. http://togogenome.org/gene/61651:CKW09_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A240BIL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A240ADM7 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/61651:CKW09_RS23860 ^@ http://purl.uniprot.org/uniprot/A0A240CGM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/61651:CKW09_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A240BYW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/61651:CKW09_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A240C763 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A240BSN3 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/61651:CKW09_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A240C3H8 ^@ Similarity ^@ Belongs to the UPF0181 family. http://togogenome.org/gene/61651:CKW09_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A240APK6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CutA family.|||Binds 1 copper ion per subunit.|||Cytoplasm|||Homotrimer.|||Involved in resistance toward heavy metals. http://togogenome.org/gene/61651:CKW09_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A240BUU2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/61651:CKW09_RS23435 ^@ http://purl.uniprot.org/uniprot/A0A240CE41 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A240BIL8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/61651:CKW09_RS14710 ^@ http://purl.uniprot.org/uniprot/A0A240C6D8 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/61651:CKW09_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A240B6L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS14830 ^@ http://purl.uniprot.org/uniprot/A0A240C6H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/61651:CKW09_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A240BWH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.|||Cell membrane|||K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. http://togogenome.org/gene/61651:CKW09_RS23695 ^@ http://purl.uniprot.org/uniprot/A0A240CGB8 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/61651:CKW09_RS20735 ^@ http://purl.uniprot.org/uniprot/A0A240CAI1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/61651:CKW09_RS20570 ^@ http://purl.uniprot.org/uniprot/A0A240CAJ2 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/61651:CKW09_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A240AZU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/61651:CKW09_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A240BZV1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/61651:CKW09_RS18170 ^@ http://purl.uniprot.org/uniprot/A0A240C7U3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/61651:CKW09_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A240BRL5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS16845 ^@ http://purl.uniprot.org/uniprot/A0A240C6Y4 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/61651:CKW09_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A240AZW3 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS12380 ^@ http://purl.uniprot.org/uniprot/A0A240C2I8 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A240BS55 ^@ Similarity ^@ Belongs to the UPF0319 family. http://togogenome.org/gene/61651:CKW09_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A240ARB0 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/61651:CKW09_RS11860 ^@ http://purl.uniprot.org/uniprot/A0A240BZN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A240A5X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS21890 ^@ http://purl.uniprot.org/uniprot/A0A240CEG1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/61651:CKW09_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A240AEX1 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/61651:CKW09_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A240BWP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/61651:CKW09_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A240BU77 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family. MukB subfamily.|||Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.|||Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.|||The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS19935 ^@ http://purl.uniprot.org/uniprot/A0A240CC33 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A240AZT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/61651:CKW09_RS20330 ^@ http://purl.uniprot.org/uniprot/A0A240CA27 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/61651:CKW09_RS24130 ^@ http://purl.uniprot.org/uniprot/A0A240CGV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A240AWR4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A240AY40 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/61651:CKW09_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A240A4X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13660 ^@ http://purl.uniprot.org/uniprot/A0A240C368 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/61651:CKW09_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A240ABJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family.|||Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A240BYY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS14190 ^@ http://purl.uniprot.org/uniprot/A0A240C3R8 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/61651:CKW09_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A240C386 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A240BZH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TonB family.|||Cell inner membrane|||Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/61651:CKW09_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A240B1J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/61651:CKW09_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A240BXD6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/61651:CKW09_RS23925 ^@ http://purl.uniprot.org/uniprot/A0A240CEL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A240AYT5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/61651:CKW09_RS11785 ^@ http://purl.uniprot.org/uniprot/A0A240BZU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22640 ^@ http://purl.uniprot.org/uniprot/A0A240CCK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.|||Cell inner membrane|||Interacts with KefB.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. http://togogenome.org/gene/61651:CKW09_RS20205 ^@ http://purl.uniprot.org/uniprot/A0A240CCC9 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/61651:CKW09_RS22380 ^@ http://purl.uniprot.org/uniprot/A0A240CDE5 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/61651:CKW09_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A240BLM7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/61651:CKW09_RS23540 ^@ http://purl.uniprot.org/uniprot/A0A240CGQ4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/61651:CKW09_RS14750 ^@ http://purl.uniprot.org/uniprot/A0A240C453 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS08960 ^@ http://purl.uniprot.org/uniprot/A0A240BRZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/61651:CKW09_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A240C2P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A240AFU6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A240C8D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.|||Belongs to the RseA family.|||Cell inner membrane|||Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB. http://togogenome.org/gene/61651:CKW09_RS24210 ^@ http://purl.uniprot.org/uniprot/A0A240CGZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/61651:CKW09_RS09765 ^@ http://purl.uniprot.org/uniprot/A0A240BUK6 ^@ Function|||Similarity ^@ Belongs to the DtxR/MntR family.|||In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP. http://togogenome.org/gene/61651:CKW09_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A240BKD8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A240BZC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS19870 ^@ http://purl.uniprot.org/uniprot/A0A240C9U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A240BME6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/61651:CKW09_RS13130 ^@ http://purl.uniprot.org/uniprot/A0A240C2B1 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A240BR21 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/61651:CKW09_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A240BRK5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS15475 ^@ http://purl.uniprot.org/uniprot/A0A240C5I2 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A240CAL5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/61651:CKW09_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A240AYB4 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/61651:CKW09_RS17090 ^@ http://purl.uniprot.org/uniprot/A0A240C760 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13405 ^@ http://purl.uniprot.org/uniprot/A0A240C2K0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A240APZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/61651:CKW09_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A240B224 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/61651:CKW09_RS14055 ^@ http://purl.uniprot.org/uniprot/A0A240C3L6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/61651:CKW09_RS17125 ^@ http://purl.uniprot.org/uniprot/A0A240C6S9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/61651:CKW09_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A240C651 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/61651:CKW09_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A240CAP9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A240BZG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A240BTA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/61651:CKW09_RS22360 ^@ http://purl.uniprot.org/uniprot/A0A240CC98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/61651:CKW09_RS19225 ^@ http://purl.uniprot.org/uniprot/A0A240CBF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS23380 ^@ http://purl.uniprot.org/uniprot/A0A240CDT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Cdh family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A240BWR9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A240B128 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/61651:CKW09_RS14990 ^@ http://purl.uniprot.org/uniprot/A0A240C4L4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/61651:CKW09_RS19830 ^@ http://purl.uniprot.org/uniprot/A0A240CBU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A240BUF1 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates.|||FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A240BJ63 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/61651:CKW09_RS23250 ^@ http://purl.uniprot.org/uniprot/A0A240CDD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS22550 ^@ http://purl.uniprot.org/uniprot/A0A240CF72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A240AXF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/61651:CKW09_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A240BTZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS16770 ^@ http://purl.uniprot.org/uniprot/A0A240C7J2 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/61651:CKW09_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A240BKR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/61651:CKW09_RS15540 ^@ http://purl.uniprot.org/uniprot/A0A240C4Z7 ^@ Function|||Similarity ^@ Belongs to the RcsA family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes. http://togogenome.org/gene/61651:CKW09_RS18260 ^@ http://purl.uniprot.org/uniprot/A0A240C9L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A240C219 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/61651:CKW09_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A240C3C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/61651:CKW09_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A240CA82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A240B2D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/61651:CKW09_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A240BRT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22975 ^@ http://purl.uniprot.org/uniprot/A0A240CF66 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/61651:CKW09_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A240BMB5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS20635 ^@ http://purl.uniprot.org/uniprot/A0A240CAJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS09580 ^@ http://purl.uniprot.org/uniprot/A0A240BWN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17695 ^@ http://purl.uniprot.org/uniprot/A0A240C783 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS24265 ^@ http://purl.uniprot.org/uniprot/A0A240CH95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/61651:CKW09_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A240AQX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS20690 ^@ http://purl.uniprot.org/uniprot/A0A240CCP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A240BSQ3 ^@ Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer. http://togogenome.org/gene/61651:CKW09_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A240B0K5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS14000 ^@ http://purl.uniprot.org/uniprot/A0A240C4D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/61651:CKW09_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A240C395 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A240BLZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS17610 ^@ http://purl.uniprot.org/uniprot/A0A240C6P8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A240ACN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anaerobic G-3-P dehydrogenase subunit B family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. http://togogenome.org/gene/61651:CKW09_RS23905 ^@ http://purl.uniprot.org/uniprot/A0A240CEU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A240B0B2 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A240BXJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A240BWQ8 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A240BLI3 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/61651:CKW09_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A240BFC3 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/61651:CKW09_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A240C2X5 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/61651:CKW09_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A240BUP4 ^@ Function|||Similarity ^@ Belongs to the thiamine kinase family.|||Catalyzes the phosphorylation of thiamine to thiamine phosphate. http://togogenome.org/gene/61651:CKW09_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A240C7F7 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/61651:CKW09_RS19260 ^@ http://purl.uniprot.org/uniprot/A0A240C8W2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A240AVJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A240BP83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A240B1Q5 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A240AP27 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/61651:CKW09_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A240A5V9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A240A540 ^@ Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.|||Reaction proceeds via an anti dehydration. http://togogenome.org/gene/61651:CKW09_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A240C7Q3 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/61651:CKW09_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A240BQH5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/61651:CKW09_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A240BYT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/61651:CKW09_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A240B2Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/61651:CKW09_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A240AZR6 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/61651:CKW09_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A240BNI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Dps family.|||Cytoplasm|||During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.|||Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited. http://togogenome.org/gene/61651:CKW09_RS21665 ^@ http://purl.uniprot.org/uniprot/A0A240CE71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS20085 ^@ http://purl.uniprot.org/uniprot/A0A240CA35 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/61651:CKW09_RS19690 ^@ http://purl.uniprot.org/uniprot/A0A240C9U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS13790 ^@ http://purl.uniprot.org/uniprot/A0A240C2Y7 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/61651:CKW09_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A240C1G1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS23615 ^@ http://purl.uniprot.org/uniprot/A0A240CG75 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/61651:CKW09_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A240BND0 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/61651:CKW09_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A240BXF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/61651:CKW09_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A240C265 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS20220 ^@ http://purl.uniprot.org/uniprot/A0A240CCT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/61651:CKW09_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A240BSB5 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/61651:CKW09_RS19520 ^@ http://purl.uniprot.org/uniprot/A0A240CBV0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/61651:CKW09_RS11030 ^@ http://purl.uniprot.org/uniprot/A0A240BYF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.|||Cell membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/61651:CKW09_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A240C721 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/61651:CKW09_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A240C378 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS21900 ^@ http://purl.uniprot.org/uniprot/A0A240CDX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/61651:CKW09_RS20480 ^@ http://purl.uniprot.org/uniprot/A0A240CA84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS15080 ^@ http://purl.uniprot.org/uniprot/A0A240C6S6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A240AJ03 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS22305 ^@ http://purl.uniprot.org/uniprot/A0A240CC88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AceK family.|||Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A240BGI2 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/61651:CKW09_RS18650 ^@ http://purl.uniprot.org/uniprot/A0A240C8C5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/61651:CKW09_RS22125 ^@ http://purl.uniprot.org/uniprot/A0A240CE63 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs. http://togogenome.org/gene/61651:CKW09_RS22955 ^@ http://purl.uniprot.org/uniprot/A0A240CCT0 ^@ Function|||Similarity ^@ Belongs to the FeoC family.|||May function as a transcriptional regulator that controls feoABC expression. http://togogenome.org/gene/61651:CKW09_RS21100 ^@ http://purl.uniprot.org/uniprot/A0A240CAY4 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/61651:CKW09_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A240C3J6 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/61651:CKW09_RS17870 ^@ http://purl.uniprot.org/uniprot/A0A240C9S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZipA family.|||Cell inner membrane|||Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.|||Interacts with FtsZ via their C-terminal domains. http://togogenome.org/gene/61651:CKW09_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A240C1E7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/61651:CKW09_RS19445 ^@ http://purl.uniprot.org/uniprot/A0A240C950 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/61651:CKW09_RS11655 ^@ http://purl.uniprot.org/uniprot/A0A240C041 ^@ Function|||Similarity ^@ Belongs to the class-C beta-lactamase family.|||This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. http://togogenome.org/gene/61651:CKW09_RS21770 ^@ http://purl.uniprot.org/uniprot/A0A240CBK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rnk family.|||Interacts with the RNA polymerase.|||May act as an anti-Gre factor. http://togogenome.org/gene/61651:CKW09_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A240C7A6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A240BRE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/61651:CKW09_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A240AZQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS20125 ^@ http://purl.uniprot.org/uniprot/A0A240CA44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A240BVL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A240AYL9 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/61651:CKW09_RS09040 ^@ http://purl.uniprot.org/uniprot/A0A240BUF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A240BRV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS15705 ^@ http://purl.uniprot.org/uniprot/A0A240C5S1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A240C9F3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A240BYW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/61651:CKW09_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A240BXT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS14935 ^@ http://purl.uniprot.org/uniprot/A0A240C483 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/61651:CKW09_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A240C6T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22585 ^@ http://purl.uniprot.org/uniprot/A0A240CDN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/61651:CKW09_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A240AHS2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS13305 ^@ http://purl.uniprot.org/uniprot/A0A240C2F2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/61651:CKW09_RS22840 ^@ http://purl.uniprot.org/uniprot/A0A240CCL1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A240B2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS23610 ^@ http://purl.uniprot.org/uniprot/A0A240CDW4 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/61651:CKW09_RS23805 ^@ http://purl.uniprot.org/uniprot/A0A240CEM5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/61651:CKW09_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A240AP49 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/61651:CKW09_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A240BRQ4 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/61651:CKW09_RS22285 ^@ http://purl.uniprot.org/uniprot/A0A240CEA0 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/61651:CKW09_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A240C2W9 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS23355 ^@ http://purl.uniprot.org/uniprot/A0A240CDQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A240AZF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dGTPase family. Type 1 subfamily.|||Homotetramer.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/61651:CKW09_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A240B4R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/61651:CKW09_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A240B3P9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/61651:CKW09_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A240BVE6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/61651:CKW09_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A240BNE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/61651:CKW09_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A240BKP1 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/61651:CKW09_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A240BG08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A240C316 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/61651:CKW09_RS21795 ^@ http://purl.uniprot.org/uniprot/A0A240CBZ3 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/61651:CKW09_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A240AP00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A240BT53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A240C5T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ.|||Membrane http://togogenome.org/gene/61651:CKW09_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A240AZE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A240BTE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS15450 ^@ http://purl.uniprot.org/uniprot/A0A240C7G7 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/61651:CKW09_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A240BHJ8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/61651:CKW09_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A240AQN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/61651:CKW09_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A240B3G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS23300 ^@ http://purl.uniprot.org/uniprot/A0A240CDL9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A240AYH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/61651:CKW09_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A240BKC8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/61651:CKW09_RS17710 ^@ http://purl.uniprot.org/uniprot/A0A240C971 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/61651:CKW09_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A240AD52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protease inhibitor I38 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS21135 ^@ http://purl.uniprot.org/uniprot/A0A240CAZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsP family.|||Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A240C2G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS21865 ^@ http://purl.uniprot.org/uniprot/A0A240CBQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A240C6X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS05700 ^@ http://purl.uniprot.org/uniprot/A0A240BIH2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A240B4N9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/61651:CKW09_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A240ADM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PanZ/PanM family.|||Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.|||Interacts with PanD in the presence of CoA. http://togogenome.org/gene/61651:CKW09_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A240AQ13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/61651:CKW09_RS19475 ^@ http://purl.uniprot.org/uniprot/A0A240CAA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. http://togogenome.org/gene/61651:CKW09_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A240BTP6 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/61651:CKW09_RS13320 ^@ http://purl.uniprot.org/uniprot/A0A240C4C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A240C8Q8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A240ANG9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD). http://togogenome.org/gene/61651:CKW09_RS19735 ^@ http://purl.uniprot.org/uniprot/A0A240CC78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.|||Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A240C4C3 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/61651:CKW09_RS15895 ^@ http://purl.uniprot.org/uniprot/A0A240C6G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS21355 ^@ http://purl.uniprot.org/uniprot/A0A240CBC8 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A240AFD9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/61651:CKW09_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A240AQH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17415 ^@ http://purl.uniprot.org/uniprot/A0A240C6Z9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/61651:CKW09_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A240A5G1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/61651:CKW09_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A240BGB7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A240AXP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/61651:CKW09_RS16680 ^@ http://purl.uniprot.org/uniprot/A0A240C7F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A240BL20 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/61651:CKW09_RS21560 ^@ http://purl.uniprot.org/uniprot/A0A240CBD4 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/61651:CKW09_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A240BFR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16595 ^@ http://purl.uniprot.org/uniprot/A0A240C6B8 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/61651:CKW09_RS16690 ^@ http://purl.uniprot.org/uniprot/A0A240C8H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS12355 ^@ http://purl.uniprot.org/uniprot/A0A240C0R9 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/61651:CKW09_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A240BQV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/61651:CKW09_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A240BTU8 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/61651:CKW09_RS21035 ^@ http://purl.uniprot.org/uniprot/A0A240CDJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/61651:CKW09_RS14285 ^@ http://purl.uniprot.org/uniprot/A0A240C3I6 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/61651:CKW09_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A240AY65 ^@ Caution|||Similarity ^@ Belongs to the phosphoglycerate mutase family. GpmB subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS21630 ^@ http://purl.uniprot.org/uniprot/A0A240CE62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/61651:CKW09_RS22390 ^@ http://purl.uniprot.org/uniprot/A0A240CED1 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/61651:CKW09_RS24270 ^@ http://purl.uniprot.org/uniprot/A0A240CH24 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/61651:CKW09_RS22560 ^@ http://purl.uniprot.org/uniprot/A0A240CEM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A240C704 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A240AIU7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/61651:CKW09_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A240C5F4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/61651:CKW09_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A240B2Y1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS23710 ^@ http://purl.uniprot.org/uniprot/A0A240CGD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/61651:CKW09_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A240C9F5 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/61651:CKW09_RS18670 ^@ http://purl.uniprot.org/uniprot/A0A240C819 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/61651:CKW09_RS22075 ^@ http://purl.uniprot.org/uniprot/A0A240CE43 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/61651:CKW09_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A240C6N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/61651:CKW09_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A240A9K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A240AQU0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/61651:CKW09_RS23585 ^@ http://purl.uniprot.org/uniprot/A0A240CEA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A240A5W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS19180 ^@ http://purl.uniprot.org/uniprot/A0A240CBC7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/61651:CKW09_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A240C180 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. http://togogenome.org/gene/61651:CKW09_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A240C799 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A240C4N1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS21675 ^@ http://purl.uniprot.org/uniprot/A0A240CCM9 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/61651:CKW09_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A240BJP7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/61651:CKW09_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A240AIQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A240B4L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A240AQ25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A240BNJ3 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A240ANG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/61651:CKW09_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A240BSG7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.|||Cell inner membrane|||Component of an export pathway for enterobactin.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A240BNZ8 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/61651:CKW09_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A240AQ76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS16390 ^@ http://purl.uniprot.org/uniprot/A0A240C877 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A240BGC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A240C3B9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS22455 ^@ http://purl.uniprot.org/uniprot/A0A240CCC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/61651:CKW09_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A240B4N3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A240C7G1 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/61651:CKW09_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A240BS68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/61651:CKW09_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A240BZ75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). http://togogenome.org/gene/61651:CKW09_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A240BNL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A240BN85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16195 ^@ http://purl.uniprot.org/uniprot/A0A240C5R7 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/61651:CKW09_RS23025 ^@ http://purl.uniprot.org/uniprot/A0A240CF96 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/61651:CKW09_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A240BMR2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/61651:CKW09_RS18190 ^@ http://purl.uniprot.org/uniprot/A0A240C9E5 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/61651:CKW09_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A240BPB5 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family. http://togogenome.org/gene/61651:CKW09_RS23770 ^@ http://purl.uniprot.org/uniprot/A0A240CEB7 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/61651:CKW09_RS14250 ^@ http://purl.uniprot.org/uniprot/A0A240C3T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/61651:CKW09_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A240AAD3 ^@ Function|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. http://togogenome.org/gene/61651:CKW09_RS24225 ^@ http://purl.uniprot.org/uniprot/A0A240CF26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/61651:CKW09_RS24035 ^@ http://purl.uniprot.org/uniprot/A0A240CEK3 ^@ Function|||Similarity|||Subunit ^@ A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.|||Belongs to the YihI family.|||Interacts with Der. http://togogenome.org/gene/61651:CKW09_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A240C461 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/61651:CKW09_RS19040 ^@ http://purl.uniprot.org/uniprot/A0A240C9P0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A240C6S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21870 ^@ http://purl.uniprot.org/uniprot/A0A240CC23 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/61651:CKW09_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A240A7G1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/61651:CKW09_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A240AY21 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/61651:CKW09_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A240ABA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A240C7L2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/61651:CKW09_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A240BWD9 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/61651:CKW09_RS23720 ^@ http://purl.uniprot.org/uniprot/A0A240CEH7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A240ADP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/61651:CKW09_RS23030 ^@ http://purl.uniprot.org/uniprot/A0A240CD59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/61651:CKW09_RS15650 ^@ http://purl.uniprot.org/uniprot/A0A240C7D7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/61651:CKW09_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A240BSW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukE family.|||Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS22655 ^@ http://purl.uniprot.org/uniprot/A0A240CCE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A240AFF5 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/61651:CKW09_RS16405 ^@ http://purl.uniprot.org/uniprot/A0A240C6I0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A240B3I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/61651:CKW09_RS21020 ^@ http://purl.uniprot.org/uniprot/A0A240CD42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A240AYI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A240BXJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A240BUZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS23965 ^@ http://purl.uniprot.org/uniprot/A0A240CEG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A240BVC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.|||Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS13525 ^@ http://purl.uniprot.org/uniprot/A0A240C3S5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/61651:CKW09_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A240B006 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A240AXW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.|||Cell inner membrane|||Homodimer. Interacts with KefC.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC. http://togogenome.org/gene/61651:CKW09_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A240C3T5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/61651:CKW09_RS20740 ^@ http://purl.uniprot.org/uniprot/A0A240CCW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/61651:CKW09_RS16160 ^@ http://purl.uniprot.org/uniprot/A0A240C5W8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A240C4U8 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/61651:CKW09_RS14930 ^@ http://purl.uniprot.org/uniprot/A0A240C4I3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/61651:CKW09_RS13435 ^@ http://purl.uniprot.org/uniprot/A0A240C2S0 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/61651:CKW09_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A240C0P5 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/61651:CKW09_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A240ARE1 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/61651:CKW09_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A240AES1 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/61651:CKW09_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A240CB46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS19375 ^@ http://purl.uniprot.org/uniprot/A0A240CB47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/61651:CKW09_RS18400 ^@ http://purl.uniprot.org/uniprot/A0A240C7P1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.|||Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.|||Cytoplasm|||Probably phosphorylates lipids; the in vivo substrate is unknown. http://togogenome.org/gene/61651:CKW09_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A240BP94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS21505 ^@ http://purl.uniprot.org/uniprot/A0A240CCG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/61651:CKW09_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A240BJI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/61651:CKW09_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A240BGM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS21290 ^@ http://purl.uniprot.org/uniprot/A0A240CB04 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/61651:CKW09_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A240C0N2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A240C475 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/61651:CKW09_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A240B1Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/61651:CKW09_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A240ARF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TamA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A240C408 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M23B family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A240BZC9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/61651:CKW09_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A240C1N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A240B1J4 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/61651:CKW09_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A240BXM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/61651:CKW09_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A240BLR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A240BFD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18575 ^@ http://purl.uniprot.org/uniprot/A0A240C892 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A240B2U1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/61651:CKW09_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A240AYX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS16085 ^@ http://purl.uniprot.org/uniprot/A0A240C5I8 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/61651:CKW09_RS16230 ^@ http://purl.uniprot.org/uniprot/A0A240C8E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A240BS16 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/61651:CKW09_RS22505 ^@ http://purl.uniprot.org/uniprot/A0A240CCD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/61651:CKW09_RS13425 ^@ http://purl.uniprot.org/uniprot/A0A240C2L1 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/61651:CKW09_RS13745 ^@ http://purl.uniprot.org/uniprot/A0A240C3N3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RssB family.|||Binds to RpoS.|||Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.|||Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. http://togogenome.org/gene/61651:CKW09_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A240AA79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/61651:CKW09_RS14275 ^@ http://purl.uniprot.org/uniprot/A0A240C5K7 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/61651:CKW09_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A240C9B3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/61651:CKW09_RS17235 ^@ http://purl.uniprot.org/uniprot/A0A240C930 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/61651:CKW09_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A240APP0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/61651:CKW09_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A240AXH6 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/61651:CKW09_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A240C1R8 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/61651:CKW09_RS21820 ^@ http://purl.uniprot.org/uniprot/A0A240CC04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A240AXV9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/61651:CKW09_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A240C6B3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A240C7D1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/61651:CKW09_RS22965 ^@ http://purl.uniprot.org/uniprot/A0A240CD21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.|||Cytoplasm|||Monomer.|||The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. http://togogenome.org/gene/61651:CKW09_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A240BWX9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/61651:CKW09_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A240C3J7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/61651:CKW09_RS17255 ^@ http://purl.uniprot.org/uniprot/A0A240C6H9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/61651:CKW09_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A240BGW3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/61651:CKW09_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A240C124 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the thioesterase PaaI family.|||Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).|||Homotetramer. Dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A240BYK0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A240A5E0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/61651:CKW09_RS20600 ^@ http://purl.uniprot.org/uniprot/A0A240CAK5 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/61651:CKW09_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A240APX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A240BVP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS11740 ^@ http://purl.uniprot.org/uniprot/A0A240BZT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS22210 ^@ http://purl.uniprot.org/uniprot/A0A240CE76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS19680 ^@ http://purl.uniprot.org/uniprot/A0A240CBP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23880 ^@ http://purl.uniprot.org/uniprot/A0A240CGN9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/61651:CKW09_RS17730 ^@ http://purl.uniprot.org/uniprot/A0A240C738 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/61651:CKW09_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A240AHN8 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/61651:CKW09_RS21450 ^@ http://purl.uniprot.org/uniprot/A0A240CCE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A240AU89 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A240BIR6 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/61651:CKW09_RS17435 ^@ http://purl.uniprot.org/uniprot/A0A240C9J3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/61651:CKW09_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A240BL32 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/61651:CKW09_RS22140 ^@ http://purl.uniprot.org/uniprot/A0A240CCC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS20495 ^@ http://purl.uniprot.org/uniprot/A0A240CAE8 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/61651:CKW09_RS23140 ^@ http://purl.uniprot.org/uniprot/A0A240CFC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21670 ^@ http://purl.uniprot.org/uniprot/A0A240CBH4 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/61651:CKW09_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A240B1U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A240C904 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A240BQA4 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/61651:CKW09_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A240C4H3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/61651:CKW09_RS19285 ^@ http://purl.uniprot.org/uniprot/A0A240C8Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A240BTP9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS18995 ^@ http://purl.uniprot.org/uniprot/A0A240C879 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/61651:CKW09_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A240AYM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/61651:CKW09_RS18080 ^@ http://purl.uniprot.org/uniprot/A0A240C7F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/61651:CKW09_RS23055 ^@ http://purl.uniprot.org/uniprot/A0A240CF62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS14640 ^@ http://purl.uniprot.org/uniprot/A0A240C6J1 ^@ Similarity ^@ Belongs to the CmpA/NrtA family. http://togogenome.org/gene/61651:CKW09_RS23400 ^@ http://purl.uniprot.org/uniprot/A0A240CE20 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A240AJL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.|||Catalyzes the proton-dependent transport of glutamate and aspartate.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS21690 ^@ http://purl.uniprot.org/uniprot/A0A240CE81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/61651:CKW09_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A240BY51 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A240AH91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/61651:CKW09_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A240ARU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A240B070 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/61651:CKW09_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A240A5J8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/61651:CKW09_RS14035 ^@ http://purl.uniprot.org/uniprot/A0A240C392 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.|||Catalyzes the excretion of spermidine.|||Cell inner membrane|||Cell membrane|||Forms a complex with MdtI.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A240C758 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/61651:CKW09_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A240BHD3 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/61651:CKW09_RS20335 ^@ http://purl.uniprot.org/uniprot/A0A240CBD3 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/61651:CKW09_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A240BSB3 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/61651:CKW09_RS22435 ^@ http://purl.uniprot.org/uniprot/A0A240CCH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/61651:CKW09_RS18580 ^@ http://purl.uniprot.org/uniprot/A0A240C9V5 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/61651:CKW09_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A240B428 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A240C059 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/61651:CKW09_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A240ACW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/61651:CKW09_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A240BH60 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/61651:CKW09_RS21230 ^@ http://purl.uniprot.org/uniprot/A0A240CB22 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates zinc uptake. May also transport other divalent cations.|||Membrane http://togogenome.org/gene/61651:CKW09_RS22895 ^@ http://purl.uniprot.org/uniprot/A0A240CD27 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/61651:CKW09_RS03800 ^@ http://purl.uniprot.org/uniprot/A0A240AXL3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane|||The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB). http://togogenome.org/gene/61651:CKW09_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A240AEP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A240C429 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS11165 ^@ http://purl.uniprot.org/uniprot/A0A240C134 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A240C291 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/61651:CKW09_RS15055 ^@ http://purl.uniprot.org/uniprot/A0A240C6R7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/61651:CKW09_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A240BXL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/61651:CKW09_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A240CC13 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/61651:CKW09_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A240B3Q2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/61651:CKW09_RS14790 ^@ http://purl.uniprot.org/uniprot/A0A240C6P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/61651:CKW09_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A240AR45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/61651:CKW09_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A240BWD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14665 ^@ http://purl.uniprot.org/uniprot/A0A240C3Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A240C868 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A240A593 ^@ Similarity|||Subunit ^@ Belongs to the KHG/KDPG aldolase family.|||Homotrimer. http://togogenome.org/gene/61651:CKW09_RS13955 ^@ http://purl.uniprot.org/uniprot/A0A240C584 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/61651:CKW09_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A240AF11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A240API1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A240BVU0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/61651:CKW09_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A240A904 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS23305 ^@ http://purl.uniprot.org/uniprot/A0A240CDM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A240BWZ4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/61651:CKW09_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A240BNH0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/61651:CKW09_RS13500 ^@ http://purl.uniprot.org/uniprot/A0A240C2K5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/61651:CKW09_RS14230 ^@ http://purl.uniprot.org/uniprot/A0A240C3Q2 ^@ Function|||Similarity ^@ Belongs to the N(4)-acetylcytidine amidohydrolase family.|||Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C). http://togogenome.org/gene/61651:CKW09_RS22620 ^@ http://purl.uniprot.org/uniprot/A0A240CEL8 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/61651:CKW09_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A240CE49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A240BJ17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS16915 ^@ http://purl.uniprot.org/uniprot/A0A240C8I1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Homotrimer.|||Membrane http://togogenome.org/gene/61651:CKW09_RS20000 ^@ http://purl.uniprot.org/uniprot/A0A240CA02 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/61651:CKW09_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A240AW83 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/61651:CKW09_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A240AGV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/61651:CKW09_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A240C0A5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS20240 ^@ http://purl.uniprot.org/uniprot/A0A240CCE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A240AZF8 ^@ Caution|||Function ^@ Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A240BTX4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A240C001 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/61651:CKW09_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A240C1H8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A240BZW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/61651:CKW09_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A240AUD5 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/61651:CKW09_RS18625 ^@ http://purl.uniprot.org/uniprot/A0A240C7V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS23755 ^@ http://purl.uniprot.org/uniprot/A0A240CH36 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/61651:CKW09_RS18240 ^@ http://purl.uniprot.org/uniprot/A0A240C8L2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A240BGH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/61651:CKW09_RS20630 ^@ http://purl.uniprot.org/uniprot/A0A240CAP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS24045 ^@ http://purl.uniprot.org/uniprot/A0A240CES0 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/61651:CKW09_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A240C0N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A240BM29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS19320 ^@ http://purl.uniprot.org/uniprot/A0A240CBK1 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family. http://togogenome.org/gene/61651:CKW09_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A240C801 ^@ Similarity ^@ Belongs to the UPF0304 family. http://togogenome.org/gene/61651:CKW09_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A240C707 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/61651:CKW09_RS23605 ^@ http://purl.uniprot.org/uniprot/A0A240CGV1 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/61651:CKW09_RS18915 ^@ http://purl.uniprot.org/uniprot/A0A240CAH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/61651:CKW09_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A240C3A6 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/61651:CKW09_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A240C745 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A240AXU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS14730 ^@ http://purl.uniprot.org/uniprot/A0A240C6E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A240C7M3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.|||Cell inner membrane|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC. http://togogenome.org/gene/61651:CKW09_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A240C8E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/61651:CKW09_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A240BZA0 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/61651:CKW09_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A240C7B4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/61651:CKW09_RS08085 ^@ http://purl.uniprot.org/uniprot/A0A240BNT9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A240BN45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A240C712 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/61651:CKW09_RS19455 ^@ http://purl.uniprot.org/uniprot/A0A240C9G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/61651:CKW09_RS19790 ^@ http://purl.uniprot.org/uniprot/A0A240C9Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/61651:CKW09_RS15405 ^@ http://purl.uniprot.org/uniprot/A0A240C7E5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/61651:CKW09_RS17080 ^@ http://purl.uniprot.org/uniprot/A0A240C6U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A240BL82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A240BX65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/61651:CKW09_RS14100 ^@ http://purl.uniprot.org/uniprot/A0A240C3G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A240B2G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS19530 ^@ http://purl.uniprot.org/uniprot/A0A240C9A7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/61651:CKW09_RS11505 ^@ http://purl.uniprot.org/uniprot/A0A240C1K4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/61651:CKW09_RS23550 ^@ http://purl.uniprot.org/uniprot/A0A240CE08 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. http://togogenome.org/gene/61651:CKW09_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A240CB65 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A240BSH9 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/61651:CKW09_RS17885 ^@ http://purl.uniprot.org/uniprot/A0A240C6U5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A240ATV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS24350 ^@ http://purl.uniprot.org/uniprot/A0A240CF86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/61651:CKW09_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A240C6Z3 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/61651:CKW09_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A240BRM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS23000 ^@ http://purl.uniprot.org/uniprot/A0A240CD25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS22405 ^@ http://purl.uniprot.org/uniprot/A0A240CDF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21660 ^@ http://purl.uniprot.org/uniprot/A0A240CDJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/61651:CKW09_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A240C3D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.|||Catalyzes the excretion of spermidine.|||Cell inner membrane|||Cell membrane|||Forms a complex with MdtJ.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14895 ^@ http://purl.uniprot.org/uniprot/A0A240C4I0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/61651:CKW09_RS22145 ^@ http://purl.uniprot.org/uniprot/A0A240CBW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/61651:CKW09_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A240B382 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/61651:CKW09_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A240B0L0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A240C7I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/61651:CKW09_RS14840 ^@ http://purl.uniprot.org/uniprot/A0A240C4G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/61651:CKW09_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A240AFA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A240BLZ8 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/61651:CKW09_RS22165 ^@ http://purl.uniprot.org/uniprot/A0A240CC21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiC family.|||Cytoplasm|||Monomer.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/61651:CKW09_RS19290 ^@ http://purl.uniprot.org/uniprot/A0A240CB23 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/61651:CKW09_RS02445 ^@ http://purl.uniprot.org/uniprot/A0A240APX7 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A240BSJ1 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/61651:CKW09_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A240BGF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/61651:CKW09_RS22230 ^@ http://purl.uniprot.org/uniprot/A0A240CC60 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/61651:CKW09_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A240APU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22815 ^@ http://purl.uniprot.org/uniprot/A0A240CCR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Monomer.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/61651:CKW09_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A240AZ43 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.|||Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A240APV9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/61651:CKW09_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A240C7K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A240BPA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A240C6C8 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/61651:CKW09_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A240AAT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WzyE family.|||Cell inner membrane|||Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/61651:CKW09_RS23465 ^@ http://purl.uniprot.org/uniprot/A0A240CG04 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/61651:CKW09_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A240ATT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS14155 ^@ http://purl.uniprot.org/uniprot/A0A240C5G8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/61651:CKW09_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A240BVX3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/61651:CKW09_RS22765 ^@ http://purl.uniprot.org/uniprot/A0A240CCQ3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/61651:CKW09_RS23275 ^@ http://purl.uniprot.org/uniprot/A0A240CDU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A240BYG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A240C2Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.|||Bacterial flagellum basal body|||Belongs to the YcgR family.|||Monomer. Interacts with the flagellar basal bodies. http://togogenome.org/gene/61651:CKW09_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A240ADI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS15375 ^@ http://purl.uniprot.org/uniprot/A0A240C732 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0187 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A240A4A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class A bacterial acid phosphatase family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A240BXZ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArnF family.|||Cell inner membrane|||Heterodimer of ArnE and ArnF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. http://togogenome.org/gene/61651:CKW09_RS17135 ^@ http://purl.uniprot.org/uniprot/A0A240C9B9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A240C7G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/61651:CKW09_RS22535 ^@ http://purl.uniprot.org/uniprot/A0A240CEL4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/61651:CKW09_RS11500 ^@ http://purl.uniprot.org/uniprot/A0A240C094 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/61651:CKW09_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A240C8E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS12120 ^@ http://purl.uniprot.org/uniprot/A0A240C086 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS24010 ^@ http://purl.uniprot.org/uniprot/A0A240CEZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/61651:CKW09_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A240AF74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.|||Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS12835 ^@ http://purl.uniprot.org/uniprot/A0A240C1J6 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/61651:CKW09_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A240ANS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS12180 ^@ http://purl.uniprot.org/uniprot/A0A240C0Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A240AS46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/61651:CKW09_RS11190 ^@ http://purl.uniprot.org/uniprot/A0A240C151 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/61651:CKW09_RS23105 ^@ http://purl.uniprot.org/uniprot/A0A240CFC6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/61651:CKW09_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A240AW51 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/61651:CKW09_RS15515 ^@ http://purl.uniprot.org/uniprot/A0A240C559 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A240ASD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS23745 ^@ http://purl.uniprot.org/uniprot/A0A240CGF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/61651:CKW09_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A240BRI3 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/61651:CKW09_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A240BWD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16800 ^@ http://purl.uniprot.org/uniprot/A0A240C7K2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/61651:CKW09_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A240BFQ5 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/61651:CKW09_RS16410 ^@ http://purl.uniprot.org/uniprot/A0A240C657 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/61651:CKW09_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A240AYK1 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.|||Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM. http://togogenome.org/gene/61651:CKW09_RS19490 ^@ http://purl.uniprot.org/uniprot/A0A240C8Y9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A240AYC2 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/61651:CKW09_RS18910 ^@ http://purl.uniprot.org/uniprot/A0A240CAG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18635 ^@ http://purl.uniprot.org/uniprot/A0A240C8C1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/61651:CKW09_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A240C2J8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PqqD family.|||Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.|||Monomer. Interacts with PqqE. http://togogenome.org/gene/61651:CKW09_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A240B2W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/61651:CKW09_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A240B0T2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/61651:CKW09_RS22385 ^@ http://purl.uniprot.org/uniprot/A0A240CCA6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/61651:CKW09_RS21440 ^@ http://purl.uniprot.org/uniprot/A0A240CDY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MzrA family.|||Cell inner membrane|||Interacts with EnvZ.|||Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. http://togogenome.org/gene/61651:CKW09_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A240BHR0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A240C165 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A240AY67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/61651:CKW09_RS23740 ^@ http://purl.uniprot.org/uniprot/A0A240CE93 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS18930 ^@ http://purl.uniprot.org/uniprot/A0A240C8C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS13905 ^@ http://purl.uniprot.org/uniprot/A0A240C2T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GhoT/OrtT toxin family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS11755 ^@ http://purl.uniprot.org/uniprot/A0A240C1I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18140 ^@ http://purl.uniprot.org/uniprot/A0A240C9D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0370 family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A240BYB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.|||Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS14680 ^@ http://purl.uniprot.org/uniprot/A0A240C423 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A240AZF5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/61651:CKW09_RS21065 ^@ http://purl.uniprot.org/uniprot/A0A240CAX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17265 ^@ http://purl.uniprot.org/uniprot/A0A240C8Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A240BST5 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A240ABH2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phospholipase A1 family.|||Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.|||Cell outer membrane|||Homodimer; dimerization is reversible, and the dimeric form is the active one.|||Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.|||Membrane http://togogenome.org/gene/61651:CKW09_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A240BW12 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/61651:CKW09_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A240AZR1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A240C8C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS19435 ^@ http://purl.uniprot.org/uniprot/A0A240CBP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A240AXM1 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/61651:CKW09_RS23155 ^@ http://purl.uniprot.org/uniprot/A0A240CDK1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/61651:CKW09_RS21295 ^@ http://purl.uniprot.org/uniprot/A0A240CC94 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/61651:CKW09_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A240BUT4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A240BPF2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/61651:CKW09_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A240BJ60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/61651:CKW09_RS11625 ^@ http://purl.uniprot.org/uniprot/A0A240BZK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudK subfamily.|||Homodimer.|||Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate. http://togogenome.org/gene/61651:CKW09_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A240BUQ4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/61651:CKW09_RS11300 ^@ http://purl.uniprot.org/uniprot/A0A240BYZ9 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/61651:CKW09_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A240C5S8 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/61651:CKW09_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A240BFK3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/61651:CKW09_RS22515 ^@ http://purl.uniprot.org/uniprot/A0A240CCK3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/61651:CKW09_RS18045 ^@ http://purl.uniprot.org/uniprot/A0A240C9C4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A240AYC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/61651:CKW09_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A240AZ36 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.|||Homohexamer; trimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A240CB38 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/61651:CKW09_RS24280 ^@ http://purl.uniprot.org/uniprot/A0A240CF38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS23760 ^@ http://purl.uniprot.org/uniprot/A0A240CFD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS20965 ^@ http://purl.uniprot.org/uniprot/A0A240CD23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/61651:CKW09_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A240C6S1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A240BX78 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A240BNR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS13385 ^@ http://purl.uniprot.org/uniprot/A0A240C2R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A240A6U4 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/61651:CKW09_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A240APQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/61651:CKW09_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A240BS86 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/61651:CKW09_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A240C7G2 ^@ Similarity ^@ Belongs to the CcdB toxin family. http://togogenome.org/gene/61651:CKW09_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A240C812 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/61651:CKW09_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A240BPB2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A240BVV4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/61651:CKW09_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A240A6L9 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/61651:CKW09_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A240AP36 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. http://togogenome.org/gene/61651:CKW09_RS10315 ^@ http://purl.uniprot.org/uniprot/A0A240BWJ9 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/61651:CKW09_RS22395 ^@ http://purl.uniprot.org/uniprot/A0A240CF13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/61651:CKW09_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A240BR54 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/61651:CKW09_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A240B4E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A240A9H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS24220 ^@ http://purl.uniprot.org/uniprot/A0A240CEV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/61651:CKW09_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A240C3V3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/61651:CKW09_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A240AWN8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/61651:CKW09_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A240CBG0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A240BP68 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/61651:CKW09_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A240BKW4 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/61651:CKW09_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A240AVS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A240C9L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17100 ^@ http://purl.uniprot.org/uniprot/A0A240C8Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A240BFS6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/61651:CKW09_RS14885 ^@ http://purl.uniprot.org/uniprot/A0A240C6J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/61651:CKW09_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A240BVC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A240C3X5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A240AWP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/61651:CKW09_RS17875 ^@ http://purl.uniprot.org/uniprot/A0A240C7N4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/61651:CKW09_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A240ASE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/61651:CKW09_RS22580 ^@ http://purl.uniprot.org/uniprot/A0A240CCG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A240BZT6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Multidrug efflux pump that functions probably as a Na(+)/drug antiporter. http://togogenome.org/gene/61651:CKW09_RS18315 ^@ http://purl.uniprot.org/uniprot/A0A240C7J6 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/61651:CKW09_RS23670 ^@ http://purl.uniprot.org/uniprot/A0A240CE54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A240CAI7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/61651:CKW09_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A240ARN1 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A240BL13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/61651:CKW09_RS23590 ^@ http://purl.uniprot.org/uniprot/A0A240CGU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A240BR34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/61651:CKW09_RS21115 ^@ http://purl.uniprot.org/uniprot/A0A240CB57 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/61651:CKW09_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A240C6F4 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/61651:CKW09_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A240AAW5 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/61651:CKW09_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A240C623 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.|||Binds 1 zinc ion per subunit.|||Transforms N(2)-succinylglutamate into succinate and glutamate. http://togogenome.org/gene/61651:CKW09_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A240C1Q1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS23870 ^@ http://purl.uniprot.org/uniprot/A0A240CEQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/61651:CKW09_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A240B5G7 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/61651:CKW09_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A240ANE9 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/61651:CKW09_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A240CDL4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/61651:CKW09_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A240BJU3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A240BPT2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A240A8X9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A240ARI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/61651:CKW09_RS22810 ^@ http://purl.uniprot.org/uniprot/A0A240CFH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A240AXW4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/61651:CKW09_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A240B3B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS19470 ^@ http://purl.uniprot.org/uniprot/A0A240C9H9 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/61651:CKW09_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A240B302 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A240BU98 ^@ Function|||Induction|||PTM|||Similarity|||Subunit ^@ Belongs to the SulA family.|||By DNA damage, as part of the SOS response.|||Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.|||Interacts with FtsZ.|||Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired. http://togogenome.org/gene/61651:CKW09_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A240C9X0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A240BMM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23245 ^@ http://purl.uniprot.org/uniprot/A0A240CGA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS15000 ^@ http://purl.uniprot.org/uniprot/A0A240C4E8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/61651:CKW09_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A240AAJ8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family.|||Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. http://togogenome.org/gene/61651:CKW09_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A240BYI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A240AGU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/61651:CKW09_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A240AHH5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/61651:CKW09_RS22565 ^@ http://purl.uniprot.org/uniprot/A0A240CCH5 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/61651:CKW09_RS19395 ^@ http://purl.uniprot.org/uniprot/A0A240C9D6 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/61651:CKW09_RS19970 ^@ http://purl.uniprot.org/uniprot/A0A240CB27 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/61651:CKW09_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A240BH89 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/61651:CKW09_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A240BNF0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A240BV12 ^@ Function|||Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.|||Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo. http://togogenome.org/gene/61651:CKW09_RS20050 ^@ http://purl.uniprot.org/uniprot/A0A240CA25 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A240BKJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A240BXY2 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/61651:CKW09_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A240C2P8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/61651:CKW09_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A240C826 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A240C5B7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/61651:CKW09_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A240C0L3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aldolase class II family. RhaD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS21225 ^@ http://purl.uniprot.org/uniprot/A0A240CDQ3 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/61651:CKW09_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A240BRU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A240BTZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A240C1Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0283 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17210 ^@ http://purl.uniprot.org/uniprot/A0A240C6R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A240AU65 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A240BQN2 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/61651:CKW09_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A240BQL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A240C0E7 ^@ Caution|||Function|||Similarity ^@ Belongs to the rhamnulokinase family.|||Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS14755 ^@ http://purl.uniprot.org/uniprot/A0A240C6E9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/61651:CKW09_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A240BPR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A240BZA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/61651:CKW09_RS23425 ^@ http://purl.uniprot.org/uniprot/A0A240CFY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A240AYU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/61651:CKW09_RS18955 ^@ http://purl.uniprot.org/uniprot/A0A240C8F1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A240BTK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A240BZ06 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.|||Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. http://togogenome.org/gene/61651:CKW09_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A240AXD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Cell inner membrane|||Involved in succinate export with YjjP. Both proteins are required for export.|||Membrane|||The transporter is composed of YjjB and YjjP. http://togogenome.org/gene/61651:CKW09_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A240B314 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/61651:CKW09_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A240CAG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/61651:CKW09_RS21280 ^@ http://purl.uniprot.org/uniprot/A0A240CBH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/61651:CKW09_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A240AQ83 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/61651:CKW09_RS20440 ^@ http://purl.uniprot.org/uniprot/A0A240CAD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A240AT65 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/61651:CKW09_RS21565 ^@ http://purl.uniprot.org/uniprot/A0A240CB89 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/61651:CKW09_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A240AYM0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/61651:CKW09_RS19795 ^@ http://purl.uniprot.org/uniprot/A0A240CA05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS19195 ^@ http://purl.uniprot.org/uniprot/A0A240CAX1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A240ARK5 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/61651:CKW09_RS23530 ^@ http://purl.uniprot.org/uniprot/A0A240CDX2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/61651:CKW09_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A240AHJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/61651:CKW09_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A240BMP8 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/61651:CKW09_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A240BR32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A240BJ42 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A240BLV1 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/61651:CKW09_RS23890 ^@ http://purl.uniprot.org/uniprot/A0A240CEI2 ^@ Similarity ^@ Belongs to the UPF0758 family. YicR subfamily. http://togogenome.org/gene/61651:CKW09_RS12990 ^@ http://purl.uniprot.org/uniprot/A0A240C2W6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/61651:CKW09_RS21300 ^@ http://purl.uniprot.org/uniprot/A0A240CDC8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/61651:CKW09_RS21975 ^@ http://purl.uniprot.org/uniprot/A0A240CBQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/61651:CKW09_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A240AYP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS21185 ^@ http://purl.uniprot.org/uniprot/A0A240CD38 ^@ Function|||Similarity|||Subunit ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily.|||Belongs to the Nudix hydrolase family. NudK subfamily.|||Homodimer.|||Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate. http://togogenome.org/gene/61651:CKW09_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A240BMJ4 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/61651:CKW09_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A240BFZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/61651:CKW09_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A240BHW7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/61651:CKW09_RS23795 ^@ http://purl.uniprot.org/uniprot/A0A240CH56 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A240BRZ1 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/61651:CKW09_RS19510 ^@ http://purl.uniprot.org/uniprot/A0A240CAD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A240BMG0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/61651:CKW09_RS21515 ^@ http://purl.uniprot.org/uniprot/A0A240CDE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/61651:CKW09_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A240C7M4 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/61651:CKW09_RS13825 ^@ http://purl.uniprot.org/uniprot/A0A240C2R0 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/61651:CKW09_RS18265 ^@ http://purl.uniprot.org/uniprot/A0A240C7D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A240AQE2 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/61651:CKW09_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A240BM50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/61651:CKW09_RS20405 ^@ http://purl.uniprot.org/uniprot/A0A240CAC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A240C3G7 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/61651:CKW09_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A240BT48 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer and homodimer.|||The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.|||With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. http://togogenome.org/gene/61651:CKW09_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A240C128 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A240BN89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/61651:CKW09_RS15425 ^@ http://purl.uniprot.org/uniprot/A0A240C7F6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/61651:CKW09_RS18810 ^@ http://purl.uniprot.org/uniprot/A0A240C8L5 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/61651:CKW09_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A240C044 ^@ Cofactor ^@ Binds 2 manganese ions per subunit. http://togogenome.org/gene/61651:CKW09_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A240C9R1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/61651:CKW09_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A240B567 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Crl family.|||Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A240B0D8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YdjC deacetylase family. ChbG subfamily.|||Cytoplasm|||Homodimer.|||Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF. http://togogenome.org/gene/61651:CKW09_RS17530 ^@ http://purl.uniprot.org/uniprot/A0A240C985 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/61651:CKW09_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A240AXT3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A240AGP8 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/61651:CKW09_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A240BNP7 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/61651:CKW09_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A240A6X8 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/61651:CKW09_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A240C9G6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedD family.|||Cell inner membrane|||Non-essential cell division protein that could be required for efficient cell constriction.|||The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring. http://togogenome.org/gene/61651:CKW09_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A240B0E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/61651:CKW09_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A240BLK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/61651:CKW09_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A240AFE9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A240ASH6 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/61651:CKW09_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A240BRP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS22540 ^@ http://purl.uniprot.org/uniprot/A0A240CCM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/61651:CKW09_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A240BYL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A240C2Y2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M14 family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap. http://togogenome.org/gene/61651:CKW09_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A240C017 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18035 ^@ http://purl.uniprot.org/uniprot/A0A240C6W7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS16730 ^@ http://purl.uniprot.org/uniprot/A0A240C8J4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. http://togogenome.org/gene/61651:CKW09_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A240BU05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/61651:CKW09_RS16695 ^@ http://purl.uniprot.org/uniprot/A0A240C6F5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A240BR92 ^@ Similarity|||Subunit ^@ Belongs to the threonine aldolase family.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS23685 ^@ http://purl.uniprot.org/uniprot/A0A240CGZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A240CB33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/61651:CKW09_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A240BMG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LsrG family.|||Cytoplasm|||Homodimer.|||Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD). http://togogenome.org/gene/61651:CKW09_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A240AS44 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A240BW78 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/61651:CKW09_RS15410 ^@ http://purl.uniprot.org/uniprot/A0A240C5Y3 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/61651:CKW09_RS18680 ^@ http://purl.uniprot.org/uniprot/A0A240C827 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Homohexamer.|||Probably plays an important role in intracellular peptide degradation. http://togogenome.org/gene/61651:CKW09_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A240BFI7 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/61651:CKW09_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A240AGF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/61651:CKW09_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A240B120 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A240CAC1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS22915 ^@ http://purl.uniprot.org/uniprot/A0A240CCY8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS17500 ^@ http://purl.uniprot.org/uniprot/A0A240C749 ^@ Similarity ^@ Belongs to the UPF0381 family. http://togogenome.org/gene/61651:CKW09_RS18725 ^@ http://purl.uniprot.org/uniprot/A0A240C850 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A240BG58 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/61651:CKW09_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A240B2Y6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrC family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/61651:CKW09_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A240AYK5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A240BZB9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/61651:CKW09_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A240AWZ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/61651:CKW09_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A240BR46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A240C511 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/61651:CKW09_RS15045 ^@ http://purl.uniprot.org/uniprot/A0A240C6G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS20780 ^@ http://purl.uniprot.org/uniprot/A0A240CAR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS16945 ^@ http://purl.uniprot.org/uniprot/A0A240C8I7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/61651:CKW09_RS23990 ^@ http://purl.uniprot.org/uniprot/A0A240CGM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0761 family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A240C740 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/61651:CKW09_RS21015 ^@ http://purl.uniprot.org/uniprot/A0A240CAR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the porin LamB (TC 1.B.3) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS10875 ^@ http://purl.uniprot.org/uniprot/A0A240BXV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22310 ^@ http://purl.uniprot.org/uniprot/A0A240CEB0 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/61651:CKW09_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A240AZ24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS23650 ^@ http://purl.uniprot.org/uniprot/A0A240CE40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS16310 ^@ http://purl.uniprot.org/uniprot/A0A240C626 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/61651:CKW09_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A240AYZ7 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/61651:CKW09_RS22880 ^@ http://purl.uniprot.org/uniprot/A0A240CD18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IgaA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A240BZV5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/61651:CKW09_RS24245 ^@ http://purl.uniprot.org/uniprot/A0A240CG56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/61651:CKW09_RS13740 ^@ http://purl.uniprot.org/uniprot/A0A240C2X7 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/61651:CKW09_RS14085 ^@ http://purl.uniprot.org/uniprot/A0A240C5X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/61651:CKW09_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A240B283 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/61651:CKW09_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A240BQZ1 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/61651:CKW09_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A240AU39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS19585 ^@ http://purl.uniprot.org/uniprot/A0A240CBZ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Xni family.|||Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.|||Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.|||Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. http://togogenome.org/gene/61651:CKW09_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A240BF05 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/61651:CKW09_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A240BU86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS22425 ^@ http://purl.uniprot.org/uniprot/A0A240CCB1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/61651:CKW09_RS24250 ^@ http://purl.uniprot.org/uniprot/A0A240CFC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/61651:CKW09_RS22530 ^@ http://purl.uniprot.org/uniprot/A0A240CC99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/61651:CKW09_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A240BS42 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/61651:CKW09_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A240AA63 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the WecD family.|||Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A240BG97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS15735 ^@ http://purl.uniprot.org/uniprot/A0A240C4V9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS19305 ^@ http://purl.uniprot.org/uniprot/A0A240C8P7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/61651:CKW09_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A240C6X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/61651:CKW09_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A240B5H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A240AUH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A240BUW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HspQ family.|||Cytoplasm|||Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. http://togogenome.org/gene/61651:CKW09_RS20075 ^@ http://purl.uniprot.org/uniprot/A0A240CA56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/61651:CKW09_RS24155 ^@ http://purl.uniprot.org/uniprot/A0A240CG07 ^@ Similarity|||Subunit ^@ Belongs to the ViaA family.|||Possible formation of a ternary complex RavA-ViaA-CadA. http://togogenome.org/gene/61651:CKW09_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A240BRE6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/61651:CKW09_RS23620 ^@ http://purl.uniprot.org/uniprot/A0A240CEC7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/61651:CKW09_RS21465 ^@ http://purl.uniprot.org/uniprot/A0A240CBA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A240C9Y9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/61651:CKW09_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A240BJ55 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/61651:CKW09_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A240BVH3 ^@ Function|||Similarity ^@ Belongs to the AB hydrolase superfamily. Hydrolase RutD family.|||Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously. http://togogenome.org/gene/61651:CKW09_RS21090 ^@ http://purl.uniprot.org/uniprot/A0A240CD09 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/61651:CKW09_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A240AYA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A240BY42 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/61651:CKW09_RS16575 ^@ http://purl.uniprot.org/uniprot/A0A240C7B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A240C341 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/61651:CKW09_RS23910 ^@ http://purl.uniprot.org/uniprot/A0A240CHB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS17965 ^@ http://purl.uniprot.org/uniprot/A0A240C780 ^@ Similarity ^@ Belongs to the acetyltransferase family. YpeA subfamily. http://togogenome.org/gene/61651:CKW09_RS13960 ^@ http://purl.uniprot.org/uniprot/A0A240C5K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family.|||Cell inner membrane|||Cell membrane|||Membrane|||Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. http://togogenome.org/gene/61651:CKW09_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A240BUV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A240C0E2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/61651:CKW09_RS21570 ^@ http://purl.uniprot.org/uniprot/A0A240CDL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/61651:CKW09_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A240C326 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/61651:CKW09_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A240AG61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS18600 ^@ http://purl.uniprot.org/uniprot/A0A240C7K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS08675 ^@ http://purl.uniprot.org/uniprot/A0A240BQX4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A240B177 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. http://togogenome.org/gene/61651:CKW09_RS11395 ^@ http://purl.uniprot.org/uniprot/A0A240BZ61 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A240APW9 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/61651:CKW09_RS21875 ^@ http://purl.uniprot.org/uniprot/A0A240CCV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/61651:CKW09_RS22890 ^@ http://purl.uniprot.org/uniprot/A0A240CE05 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/61651:CKW09_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A240A5X6 ^@ Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17120 ^@ http://purl.uniprot.org/uniprot/A0A240C7Y0 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/61651:CKW09_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A240BV20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0312 family. Type 1 subfamily.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS11405 ^@ http://purl.uniprot.org/uniprot/A0A240BYV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/61651:CKW09_RS19230 ^@ http://purl.uniprot.org/uniprot/A0A240C8J7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16180 ^@ http://purl.uniprot.org/uniprot/A0A240C8B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A240BQ61 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion.|||Homodimer.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/61651:CKW09_RS23405 ^@ http://purl.uniprot.org/uniprot/A0A240CDM1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A240BLQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A240BPS8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/61651:CKW09_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A240BV82 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the PHP family.|||Binds 3 Zn(2+) ions per subunit.|||Homotrimer. http://togogenome.org/gene/61651:CKW09_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A240BJV6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/61651:CKW09_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A240BQR4 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/61651:CKW09_RS23940 ^@ http://purl.uniprot.org/uniprot/A0A240CEK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/61651:CKW09_RS17245 ^@ http://purl.uniprot.org/uniprot/A0A240C7D0 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/61651:CKW09_RS21120 ^@ http://purl.uniprot.org/uniprot/A0A240CD19 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/61651:CKW09_RS18590 ^@ http://purl.uniprot.org/uniprot/A0A240C7Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/61651:CKW09_RS18940 ^@ http://purl.uniprot.org/uniprot/A0A240C8T0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/61651:CKW09_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A240AVQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. RsmC family.|||Cytoplasm|||Monomer.|||Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. http://togogenome.org/gene/61651:CKW09_RS22710 ^@ http://purl.uniprot.org/uniprot/A0A240CCM8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/61651:CKW09_RS14825 ^@ http://purl.uniprot.org/uniprot/A0A240C481 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A240APV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/61651:CKW09_RS24195 ^@ http://purl.uniprot.org/uniprot/A0A240CGY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21060 ^@ http://purl.uniprot.org/uniprot/A0A240CCZ8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/61651:CKW09_RS21845 ^@ http://purl.uniprot.org/uniprot/A0A240CC15 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/61651:CKW09_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A240C6B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/61651:CKW09_RS19265 ^@ http://purl.uniprot.org/uniprot/A0A240C8X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18755 ^@ http://purl.uniprot.org/uniprot/A0A240CA89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A240BZC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A240ABM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.|||Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A240AP48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS18195 ^@ http://purl.uniprot.org/uniprot/A0A240C7D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS22375 ^@ http://purl.uniprot.org/uniprot/A0A240CC91 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/61651:CKW09_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A240AB11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-1 family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS21420 ^@ http://purl.uniprot.org/uniprot/A0A240CB42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS21800 ^@ http://purl.uniprot.org/uniprot/A0A240CBH6 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/61651:CKW09_RS14945 ^@ http://purl.uniprot.org/uniprot/A0A240C3Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/61651:CKW09_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A240BYR5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/61651:CKW09_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A240BVH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A240C5R1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS23665 ^@ http://purl.uniprot.org/uniprot/A0A240CE50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/61651:CKW09_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A240C6Z8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A240ARI9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Homodimer.|||May be involved in cell division. http://togogenome.org/gene/61651:CKW09_RS24215 ^@ http://purl.uniprot.org/uniprot/A0A240CF98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/61651:CKW09_RS20265 ^@ http://purl.uniprot.org/uniprot/A0A240CA79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/61651:CKW09_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A240C2X8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/61651:CKW09_RS23290 ^@ http://purl.uniprot.org/uniprot/A0A240CFQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/61651:CKW09_RS23580 ^@ http://purl.uniprot.org/uniprot/A0A240CF49 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A240BYQ7 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/61651:CKW09_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A240BRH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A240BW02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/61651:CKW09_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A240AWR1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/61651:CKW09_RS21825 ^@ http://purl.uniprot.org/uniprot/A0A240CBI7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A240BYC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/61651:CKW09_RS12110 ^@ http://purl.uniprot.org/uniprot/A0A240C2N3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/61651:CKW09_RS15445 ^@ http://purl.uniprot.org/uniprot/A0A240C761 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/61651:CKW09_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A240BZK9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A240AS50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/61651:CKW09_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A240BM63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A240C3K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS22605 ^@ http://purl.uniprot.org/uniprot/A0A240CCI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrE/TusD family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. http://togogenome.org/gene/61651:CKW09_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A240B1K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A240BH47 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS24200 ^@ http://purl.uniprot.org/uniprot/A0A240CF88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/61651:CKW09_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A240BPC1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A240C6Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A240C8G3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS20705 ^@ http://purl.uniprot.org/uniprot/A0A240CAK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS22500 ^@ http://purl.uniprot.org/uniprot/A0A240CCP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A240C3R7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/61651:CKW09_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A240BNT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A240C3X0 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family. AstD subfamily.|||Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. http://togogenome.org/gene/61651:CKW09_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A240C6G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A240C0L9 ^@ Function|||Similarity ^@ Belongs to the glutathione peroxidase family. BtuE subfamily.|||Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. http://togogenome.org/gene/61651:CKW09_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A240BNR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell inner membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/61651:CKW09_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A240AE56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.|||Cell inner membrane|||Cell membrane|||Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/61651:CKW09_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A240BI86 ^@ Similarity ^@ Belongs to the flavodoxin family. http://togogenome.org/gene/61651:CKW09_RS19485 ^@ http://purl.uniprot.org/uniprot/A0A240CBT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A240C4A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/61651:CKW09_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A240BFX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/61651:CKW09_RS16635 ^@ http://purl.uniprot.org/uniprot/A0A240C6C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A240AZT9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/61651:CKW09_RS22720 ^@ http://purl.uniprot.org/uniprot/A0A240CFD4 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/61651:CKW09_RS14485 ^@ http://purl.uniprot.org/uniprot/A0A240C6B9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/61651:CKW09_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A240AQH4 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/61651:CKW09_RS24205 ^@ http://purl.uniprot.org/uniprot/A0A240CH59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/61651:CKW09_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A240AET2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS13605 ^@ http://purl.uniprot.org/uniprot/A0A240C2V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0259 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS17930 ^@ http://purl.uniprot.org/uniprot/A0A240C7C3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/61651:CKW09_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A240BHC4 ^@ Function|||Similarity ^@ Belongs to the AcpH family.|||Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP. http://togogenome.org/gene/61651:CKW09_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A240A4U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/61651:CKW09_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A240AR59 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/61651:CKW09_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A240C595 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/61651:CKW09_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A240AGI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/61651:CKW09_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A240BN74 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/61651:CKW09_RS11490 ^@ http://purl.uniprot.org/uniprot/A0A240BZ13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-dependent permease that transports di- and tripeptides. http://togogenome.org/gene/61651:CKW09_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A240BVD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A240ANX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A240BJB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/61651:CKW09_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A240AWN4 ^@ Function|||Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.|||Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion. http://togogenome.org/gene/61651:CKW09_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A240AZL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A240CAV0 ^@ Function|||Induction|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/61651:CKW09_RS11285 ^@ http://purl.uniprot.org/uniprot/A0A240BYU7 ^@ Domain|||Function|||Subunit ^@ Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.|||Homodimer.|||Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. http://togogenome.org/gene/61651:CKW09_RS13355 ^@ http://purl.uniprot.org/uniprot/A0A240C2M9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS10990 ^@ http://purl.uniprot.org/uniprot/A0A240C0I5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/61651:CKW09_RS20760 ^@ http://purl.uniprot.org/uniprot/A0A240CAN2 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS23015 ^@ http://purl.uniprot.org/uniprot/A0A240CD50 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A240BR71 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/61651:CKW09_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A240C230 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A240AZ49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A240BWG4 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS24145 ^@ http://purl.uniprot.org/uniprot/A0A240CGV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). http://togogenome.org/gene/61651:CKW09_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A240AYM4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/61651:CKW09_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A240BTW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acyltransferase 3 family. OpgC subfamily.|||Cell membrane|||Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. http://togogenome.org/gene/61651:CKW09_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A240BYM3 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/61651:CKW09_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A240C4I6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/61651:CKW09_RS14470 ^@ http://purl.uniprot.org/uniprot/A0A240C4W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A240AWN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A240B3Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A240C4E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family. RNase II subfamily.|||Cytoplasm|||Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. http://togogenome.org/gene/61651:CKW09_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A240CAG7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/61651:CKW09_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A240C939 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A240C0M0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/61651:CKW09_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A240C6I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A240AZB6 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A240BN36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.|||Homotetramer; dimer of dimers.|||Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. http://togogenome.org/gene/61651:CKW09_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A240AVS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS23600 ^@ http://purl.uniprot.org/uniprot/A0A240CE37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/61651:CKW09_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A240AH34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14305 ^@ http://purl.uniprot.org/uniprot/A0A240C3V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0266 family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A240BXA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LpoB family.|||Interacts with PBP1b.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). http://togogenome.org/gene/61651:CKW09_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A240C6I8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21540 ^@ http://purl.uniprot.org/uniprot/A0A240CCH4 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/61651:CKW09_RS15575 ^@ http://purl.uniprot.org/uniprot/A0A240C7M2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS06640 ^@ http://purl.uniprot.org/uniprot/A0A240BKL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/61651:CKW09_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A240BR13 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/61651:CKW09_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A240AZM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A240AD60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/61651:CKW09_RS17640 ^@ http://purl.uniprot.org/uniprot/A0A240C719 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A240C347 ^@ Similarity ^@ Belongs to the UPF0263 family. http://togogenome.org/gene/61651:CKW09_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A240C115 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A240APW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS17835 ^@ http://purl.uniprot.org/uniprot/A0A240C6T5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/61651:CKW09_RS18305 ^@ http://purl.uniprot.org/uniprot/A0A240C7J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A240B0U1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/61651:CKW09_RS21145 ^@ http://purl.uniprot.org/uniprot/A0A240CC45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/61651:CKW09_RS18860 ^@ http://purl.uniprot.org/uniprot/A0A240CAE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A240BI72 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. Cof family.|||Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P). http://togogenome.org/gene/61651:CKW09_RS22520 ^@ http://purl.uniprot.org/uniprot/A0A240CCE8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS19430 ^@ http://purl.uniprot.org/uniprot/A0A240CB77 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/61651:CKW09_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A240BTQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/61651:CKW09_RS17490 ^@ http://purl.uniprot.org/uniprot/A0A240C9K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.|||Cytoplasm|||Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.|||In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A240C702 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/61651:CKW09_RS24140 ^@ http://purl.uniprot.org/uniprot/A0A240CFZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/61651:CKW09_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A240BL93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlE subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/61651:CKW09_RS14240 ^@ http://purl.uniprot.org/uniprot/A0A240C5J9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DbpA subfamily.|||Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. http://togogenome.org/gene/61651:CKW09_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A240ATV1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/61651:CKW09_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A240BY13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/61651:CKW09_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A240C002 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/61651:CKW09_RS22150 ^@ http://purl.uniprot.org/uniprot/A0A240CE75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A240C7Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/61651:CKW09_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A240C7E1 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/61651:CKW09_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A240BM54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS17890 ^@ http://purl.uniprot.org/uniprot/A0A240C8E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/61651:CKW09_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A240BQ60 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS23825 ^@ http://purl.uniprot.org/uniprot/A0A240CEE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS19575 ^@ http://purl.uniprot.org/uniprot/A0A240C9E2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS14960 ^@ http://purl.uniprot.org/uniprot/A0A240C493 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/61651:CKW09_RS00115 ^@ http://purl.uniprot.org/uniprot/A0A240A5F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A240B4U3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/61651:CKW09_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A240C1S3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose.|||Homohexamer. http://togogenome.org/gene/61651:CKW09_RS17425 ^@ http://purl.uniprot.org/uniprot/A0A240C968 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/61651:CKW09_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A240AC41 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/61651:CKW09_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A240A6R4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhE family.|||Cytoplasm|||Necessary for formate dehydrogenase activity. http://togogenome.org/gene/61651:CKW09_RS12735 ^@ http://purl.uniprot.org/uniprot/A0A240C1G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS21945 ^@ http://purl.uniprot.org/uniprot/A0A240CC48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.|||Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/61651:CKW09_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A240AD56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcrB family.|||Cell membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered. http://togogenome.org/gene/61651:CKW09_RS20595 ^@ http://purl.uniprot.org/uniprot/A0A240CBM9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/61651:CKW09_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A240C2Z5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SelU family.|||Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.|||Monomer. http://togogenome.org/gene/61651:CKW09_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A240BT78 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/61651:CKW09_RS23075 ^@ http://purl.uniprot.org/uniprot/A0A240CF68 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/61651:CKW09_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A240BMC0 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/61651:CKW09_RS14560 ^@ http://purl.uniprot.org/uniprot/A0A240C685 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A240C0B7 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/61651:CKW09_RS13860 ^@ http://purl.uniprot.org/uniprot/A0A240C359 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/61651:CKW09_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A240BPB8 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/61651:CKW09_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A240B4Y1 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family. AroL subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The LID domain closes over the active site upon ATP binding. http://togogenome.org/gene/61651:CKW09_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A240BLJ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A240BZW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/61651:CKW09_RS23090 ^@ http://purl.uniprot.org/uniprot/A0A240CDE0 ^@ Function|||Similarity ^@ Belongs to the IolE/MocC family.|||Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). http://togogenome.org/gene/61651:CKW09_RS14445 ^@ http://purl.uniprot.org/uniprot/A0A240C4V5 ^@ Function|||Similarity ^@ Belongs to the arginine N-succinyltransferase family.|||Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. http://togogenome.org/gene/61651:CKW09_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A240C531 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A240APR6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/61651:CKW09_RS18885 ^@ http://purl.uniprot.org/uniprot/A0A240C9G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/61651:CKW09_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A240ANZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/61651:CKW09_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A240C0I2 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/61651:CKW09_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A240AXI3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/61651:CKW09_RS13075 ^@ http://purl.uniprot.org/uniprot/A0A240C314 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/61651:CKW09_RS22525 ^@ http://purl.uniprot.org/uniprot/A0A240CCQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/61651:CKW09_RS21160 ^@ http://purl.uniprot.org/uniprot/A0A240CB08 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A240AD01 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10B family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/61651:CKW09_RS23295 ^@ http://purl.uniprot.org/uniprot/A0A240CDV5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/61651:CKW09_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A240BNC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/61651:CKW09_RS22685 ^@ http://purl.uniprot.org/uniprot/A0A240CES4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A240BTH0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS19955 ^@ http://purl.uniprot.org/uniprot/A0A240CA03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23730 ^@ http://purl.uniprot.org/uniprot/A0A240CEI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS21415 ^@ http://purl.uniprot.org/uniprot/A0A240CBK8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/61651:CKW09_RS17745 ^@ http://purl.uniprot.org/uniprot/A0A240C793 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A240C388 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/61651:CKW09_RS13360 ^@ http://purl.uniprot.org/uniprot/A0A240C3I2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/61651:CKW09_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A240B2J1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/61651:CKW09_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A240B2G1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/61651:CKW09_RS24065 ^@ http://purl.uniprot.org/uniprot/A0A240CGS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/61651:CKW09_RS24240 ^@ http://purl.uniprot.org/uniprot/A0A240CF18 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A240BVK7 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/61651:CKW09_RS21435 ^@ http://purl.uniprot.org/uniprot/A0A240CB95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS09460 ^@ http://purl.uniprot.org/uniprot/A0A240BU11 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS22065 ^@ http://purl.uniprot.org/uniprot/A0A240CEN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/61651:CKW09_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A240AW09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A240C5J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A240BXW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A240ADB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/61651:CKW09_RS23100 ^@ http://purl.uniprot.org/uniprot/A0A240CD10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/61651:CKW09_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A240BRQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A240C8I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudK subfamily.|||Homodimer.|||Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate. http://togogenome.org/gene/61651:CKW09_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A240C0W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A240AHU4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/61651:CKW09_RS19465 ^@ http://purl.uniprot.org/uniprot/A0A240C983 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/61651:CKW09_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A240BHN8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/61651:CKW09_RS21240 ^@ http://purl.uniprot.org/uniprot/A0A240CB50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/61651:CKW09_RS23045 ^@ http://purl.uniprot.org/uniprot/A0A240CD54 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A240AYR6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/61651:CKW09_RS14725 ^@ http://purl.uniprot.org/uniprot/A0A240C440 ^@ Function|||Similarity ^@ Belongs to the EfeM/EfeO family.|||Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component. http://togogenome.org/gene/61651:CKW09_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A240BUI8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/61651:CKW09_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A240BIB6 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/61651:CKW09_RS17495 ^@ http://purl.uniprot.org/uniprot/A0A240C7H4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI). http://togogenome.org/gene/61651:CKW09_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A240BXR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/61651:CKW09_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A240AQP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A240BGD5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/61651:CKW09_RS14425 ^@ http://purl.uniprot.org/uniprot/A0A240C3S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A240AAX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A240BZR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A240BK17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A240AHE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/61651:CKW09_RS21920 ^@ http://purl.uniprot.org/uniprot/A0A240CBM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A240BVM6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/61651:CKW09_RS18155 ^@ http://purl.uniprot.org/uniprot/A0A240C9J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS14720 ^@ http://purl.uniprot.org/uniprot/A0A240C576 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DyP-type peroxidase family. EfeB subfamily.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS13000 ^@ http://purl.uniprot.org/uniprot/A0A240C4C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.|||Membrane http://togogenome.org/gene/61651:CKW09_RS19325 ^@ http://purl.uniprot.org/uniprot/A0A240C8Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS24185 ^@ http://purl.uniprot.org/uniprot/A0A240CF77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS23985 ^@ http://purl.uniprot.org/uniprot/A0A240CGU2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A240B1F8 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/61651:CKW09_RS19175 ^@ http://purl.uniprot.org/uniprot/A0A240C8T4 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/61651:CKW09_RS20720 ^@ http://purl.uniprot.org/uniprot/A0A240CAS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A240ANJ8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/61651:CKW09_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A240BN96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A240BQK7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/61651:CKW09_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A240ADN6 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/61651:CKW09_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A240B1Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A240CAM2 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/61651:CKW09_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A240AXF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/61651:CKW09_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A240BQP1 ^@ Function|||Similarity ^@ Belongs to the GMC oxidoreductase family.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. http://togogenome.org/gene/61651:CKW09_RS10385 ^@ http://purl.uniprot.org/uniprot/A0A240BW94 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/61651:CKW09_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A240BXK5 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family. NagK subfamily.|||Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. http://togogenome.org/gene/61651:CKW09_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A240BNU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/61651:CKW09_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A240AW30 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/61651:CKW09_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A240BT64 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/61651:CKW09_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A240BS63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmI family.|||Cytoplasm|||Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A240CAD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/61651:CKW09_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A240AYG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/61651:CKW09_RS15420 ^@ http://purl.uniprot.org/uniprot/A0A240C751 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/61651:CKW09_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A240AE49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/61651:CKW09_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A240BII5 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/61651:CKW09_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A240BL57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/61651:CKW09_RS11905 ^@ http://purl.uniprot.org/uniprot/A0A240C022 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A240AIZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A240BH33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS21285 ^@ http://purl.uniprot.org/uniprot/A0A240CB41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/61651:CKW09_RS20970 ^@ http://purl.uniprot.org/uniprot/A0A240CB00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/61651:CKW09_RS16670 ^@ http://purl.uniprot.org/uniprot/A0A240C649 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A240APG9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/61651:CKW09_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A240BFL7 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/61651:CKW09_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A240BFQ8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/61651:CKW09_RS16750 ^@ http://purl.uniprot.org/uniprot/A0A240C6C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS22545 ^@ http://purl.uniprot.org/uniprot/A0A240CCG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/61651:CKW09_RS19600 ^@ http://purl.uniprot.org/uniprot/A0A240CBH5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A240C7X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MtfA family.|||Cytoplasm|||Interacts with Mlc.|||Involved in the regulation of ptsG expression by binding and inactivating Mlc. http://togogenome.org/gene/61651:CKW09_RS18685 ^@ http://purl.uniprot.org/uniprot/A0A240C7Y7 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/61651:CKW09_RS22485 ^@ http://purl.uniprot.org/uniprot/A0A240CCI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/61651:CKW09_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A240BSZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS10250 ^@ http://purl.uniprot.org/uniprot/A0A240BVW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A240BX32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/61651:CKW09_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A240BZ91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A240BYA5 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/61651:CKW09_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A240BFA4 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/61651:CKW09_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A240BRJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS16820 ^@ http://purl.uniprot.org/uniprot/A0A240C6X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS20285 ^@ http://purl.uniprot.org/uniprot/A0A240CCV4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.|||Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS23625 ^@ http://purl.uniprot.org/uniprot/A0A240CE30 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS12405 ^@ http://purl.uniprot.org/uniprot/A0A240C365 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/61651:CKW09_RS21585 ^@ http://purl.uniprot.org/uniprot/A0A240CBE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS20620 ^@ http://purl.uniprot.org/uniprot/A0A240CAE0 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/61651:CKW09_RS20615 ^@ http://purl.uniprot.org/uniprot/A0A240CAW5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 3 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/61651:CKW09_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A240AQZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/61651:CKW09_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A240C9A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A240BZ32 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/61651:CKW09_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A240C6J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxT phosphotransferase family.|||Cell inner membrane|||Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P). http://togogenome.org/gene/61651:CKW09_RS24345 ^@ http://purl.uniprot.org/uniprot/A0A240CF15 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/61651:CKW09_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A240BQN8 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/61651:CKW09_RS14940 ^@ http://purl.uniprot.org/uniprot/A0A240C6V6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/61651:CKW09_RS21275 ^@ http://purl.uniprot.org/uniprot/A0A240CB43 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS13330 ^@ http://purl.uniprot.org/uniprot/A0A240C4X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/61651:CKW09_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A240AAC0 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/61651:CKW09_RS17315 ^@ http://purl.uniprot.org/uniprot/A0A240C836 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS21815 ^@ http://purl.uniprot.org/uniprot/A0A240CBN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell membrane|||Forms an efflux pump with AaeB. http://togogenome.org/gene/61651:CKW09_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A240BV97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS19695 ^@ http://purl.uniprot.org/uniprot/A0A240CAM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/61651:CKW09_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A240ANL2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/61651:CKW09_RS19165 ^@ http://purl.uniprot.org/uniprot/A0A240C8R4 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/61651:CKW09_RS16765 ^@ http://purl.uniprot.org/uniprot/A0A240C6I2 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/61651:CKW09_RS20185 ^@ http://purl.uniprot.org/uniprot/A0A240CA86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/61651:CKW09_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A240B0Z5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/61651:CKW09_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A240BPA3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/61651:CKW09_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A240AR22 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/61651:CKW09_RS20190 ^@ http://purl.uniprot.org/uniprot/A0A240CCS4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/61651:CKW09_RS23430 ^@ http://purl.uniprot.org/uniprot/A0A240CE35 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/61651:CKW09_RS17475 ^@ http://purl.uniprot.org/uniprot/A0A240C979 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/61651:CKW09_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A240B1T7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/61651:CKW09_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A240BQF3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/61651:CKW09_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A240A5R8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/61651:CKW09_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A240BSW4 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/61651:CKW09_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A240BRE1 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/61651:CKW09_RS22635 ^@ http://purl.uniprot.org/uniprot/A0A240CDP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.|||Cell inner membrane|||Interacts with the regulatory subunit KefG.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/61651:CKW09_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A240C8F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/61651:CKW09_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A240BYB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SufE family.|||Cytoplasm|||Homodimer. Interacts with SufS.|||Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process. http://togogenome.org/gene/61651:CKW09_RS20340 ^@ http://purl.uniprot.org/uniprot/A0A240CAA4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/61651:CKW09_RS18690 ^@ http://purl.uniprot.org/uniprot/A0A240C8F0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/61651:CKW09_RS23970 ^@ http://purl.uniprot.org/uniprot/A0A240CEN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/61651:CKW09_RS22480 ^@ http://purl.uniprot.org/uniprot/A0A240CEI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.