http://togogenome.org/gene/720554:CLOCL_RS11825 ^@ http://purl.uniprot.org/uniprot/G8LZ60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS19990 ^@ http://purl.uniprot.org/uniprot/G8LTL2 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/720554:CLOCL_RS11500 ^@ http://purl.uniprot.org/uniprot/G8LYH3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS01655 ^@ http://purl.uniprot.org/uniprot/G8M1Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18665 ^@ http://purl.uniprot.org/uniprot/G8M1P2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/720554:CLOCL_RS00650 ^@ http://purl.uniprot.org/uniprot/G8M081 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/720554:CLOCL_RS08220 ^@ http://purl.uniprot.org/uniprot/G8LSJ5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/720554:CLOCL_RS09820 ^@ http://purl.uniprot.org/uniprot/G8LW11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/720554:CLOCL_RS05965 ^@ http://purl.uniprot.org/uniprot/G8LYY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS09870 ^@ http://purl.uniprot.org/uniprot/G8LW19 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS05005 ^@ http://purl.uniprot.org/uniprot/G8LXJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS19765 ^@ http://purl.uniprot.org/uniprot/G8LSW6 ^@ Similarity ^@ Belongs to the DHPS family. http://togogenome.org/gene/720554:CLOCL_RS04540 ^@ http://purl.uniprot.org/uniprot/G8LWI8 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/720554:CLOCL_RS03270 ^@ http://purl.uniprot.org/uniprot/G8LUN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/720554:CLOCL_RS03820 ^@ http://purl.uniprot.org/uniprot/G8LVS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS11655 ^@ http://purl.uniprot.org/uniprot/G8LZ27 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS10950 ^@ http://purl.uniprot.org/uniprot/G8LXU0 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/720554:CLOCL_RS15935 ^@ http://purl.uniprot.org/uniprot/G8LWC3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 9 (cellulase E) family. http://togogenome.org/gene/720554:CLOCL_RS12950 ^@ http://purl.uniprot.org/uniprot/G8M1K0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS02295 ^@ http://purl.uniprot.org/uniprot/G8LSD5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/720554:CLOCL_RS06615 ^@ http://purl.uniprot.org/uniprot/G8M0F4 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/720554:CLOCL_RS00300 ^@ http://purl.uniprot.org/uniprot/G8LZF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS02390 ^@ http://purl.uniprot.org/uniprot/G8LT10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS12315 ^@ http://purl.uniprot.org/uniprot/G8M0L2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/720554:CLOCL_RS20230 ^@ http://purl.uniprot.org/uniprot/G8LTQ8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS02780 ^@ http://purl.uniprot.org/uniprot/G8LTT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17250 ^@ http://purl.uniprot.org/uniprot/G8LYL0 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/720554:CLOCL_RS05940 ^@ http://purl.uniprot.org/uniprot/G8LYX6 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS06510 ^@ http://purl.uniprot.org/uniprot/G8M0D3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/720554:CLOCL_RS14250 ^@ http://purl.uniprot.org/uniprot/G8LTG3 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/720554:CLOCL_RS19845 ^@ http://purl.uniprot.org/uniprot/G8LSY2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS07130 ^@ http://purl.uniprot.org/uniprot/G8M1C8 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/720554:CLOCL_RS14125 ^@ http://purl.uniprot.org/uniprot/G8LTD8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/720554:CLOCL_RS19140 ^@ http://purl.uniprot.org/uniprot/G8M2I7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 9 (cellulase E) family. http://togogenome.org/gene/720554:CLOCL_RS00395 ^@ http://purl.uniprot.org/uniprot/G8LZH4 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/720554:CLOCL_RS20100 ^@ http://purl.uniprot.org/uniprot/G8LTN5 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/720554:CLOCL_RS12985 ^@ http://purl.uniprot.org/uniprot/G8M1K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS05515 ^@ http://purl.uniprot.org/uniprot/G8LY73 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/720554:CLOCL_RS15735 ^@ http://purl.uniprot.org/uniprot/G8LW83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05155 ^@ http://purl.uniprot.org/uniprot/G8LXM5 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS19940 ^@ http://purl.uniprot.org/uniprot/G8LSZ9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/720554:CLOCL_RS18880 ^@ http://purl.uniprot.org/uniprot/G8M2E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS09240 ^@ http://purl.uniprot.org/uniprot/G8LUX0 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS11630 ^@ http://purl.uniprot.org/uniprot/G8LZ22 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS03045 ^@ http://purl.uniprot.org/uniprot/G8LTY8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS05915 ^@ http://purl.uniprot.org/uniprot/G8LYX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS16065 ^@ http://purl.uniprot.org/uniprot/G8LWT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS04635 ^@ http://purl.uniprot.org/uniprot/G8LWY1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/720554:CLOCL_RS12060 ^@ http://purl.uniprot.org/uniprot/G8LZV9 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS04815 ^@ http://purl.uniprot.org/uniprot/G8LX17 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS03515 ^@ http://purl.uniprot.org/uniprot/G8LV72 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS19920 ^@ http://purl.uniprot.org/uniprot/G8LSZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/720554:CLOCL_RS13605 ^@ http://purl.uniprot.org/uniprot/G8M324 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS19025 ^@ http://purl.uniprot.org/uniprot/G8M2H1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/720554:CLOCL_RS20540 ^@ http://purl.uniprot.org/uniprot/G8LUI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS11875 ^@ http://purl.uniprot.org/uniprot/G8LZ68 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/720554:CLOCL_RS13920 ^@ http://purl.uniprot.org/uniprot/G8LSP1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS10480 ^@ http://purl.uniprot.org/uniprot/G8LX57 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS16115 ^@ http://purl.uniprot.org/uniprot/G8LWT5 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/720554:CLOCL_RS18780 ^@ http://purl.uniprot.org/uniprot/G8M1R4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14155 ^@ http://purl.uniprot.org/uniprot/G8LTE4 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/720554:CLOCL_RS11800 ^@ http://purl.uniprot.org/uniprot/G8LZ55 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS02630 ^@ http://purl.uniprot.org/uniprot/G8LT52 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/720554:CLOCL_RS15240 ^@ http://purl.uniprot.org/uniprot/G8LV60 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS19290 ^@ http://purl.uniprot.org/uniprot/G8M367 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS16120 ^@ http://purl.uniprot.org/uniprot/G8LWT6 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/720554:CLOCL_RS06245 ^@ http://purl.uniprot.org/uniprot/G8LZN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17630 ^@ http://purl.uniprot.org/uniprot/G8LZA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/720554:CLOCL_RS16585 ^@ http://purl.uniprot.org/uniprot/G8LXG6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/720554:CLOCL_RS06910 ^@ http://purl.uniprot.org/uniprot/G8M181 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/720554:CLOCL_RS09905 ^@ http://purl.uniprot.org/uniprot/G8LW26 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS19270 ^@ http://purl.uniprot.org/uniprot/G8M363 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS02395 ^@ http://purl.uniprot.org/uniprot/G8LT11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS19065 ^@ http://purl.uniprot.org/uniprot/G8M2H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS16745 ^@ http://purl.uniprot.org/uniprot/G8LXY5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS10375 ^@ http://purl.uniprot.org/uniprot/G8LWQ6 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/720554:CLOCL_RS01895 ^@ http://purl.uniprot.org/uniprot/G8M2P6 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/720554:CLOCL_RS19150 ^@ http://purl.uniprot.org/uniprot/G8M2I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/720554:CLOCL_RS05620 ^@ http://purl.uniprot.org/uniprot/G8LY92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS08550 ^@ http://purl.uniprot.org/uniprot/G8LTB6 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/720554:CLOCL_RS02760 ^@ http://purl.uniprot.org/uniprot/G8LTT3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/720554:CLOCL_RS10160 ^@ http://purl.uniprot.org/uniprot/G8LWL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS09010 ^@ http://purl.uniprot.org/uniprot/G8LU68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS12725 ^@ http://purl.uniprot.org/uniprot/G8M1F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/720554:CLOCL_RS03275 ^@ http://purl.uniprot.org/uniprot/G8LUN9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/720554:CLOCL_RS08450 ^@ http://purl.uniprot.org/uniprot/G8LT96 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/720554:CLOCL_RS02775 ^@ http://purl.uniprot.org/uniprot/G8LTT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS12475 ^@ http://purl.uniprot.org/uniprot/G8M0P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS11455 ^@ http://purl.uniprot.org/uniprot/G8LYG9 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS04395 ^@ http://purl.uniprot.org/uniprot/G8LWF9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS08800 ^@ http://purl.uniprot.org/uniprot/G8LU25 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS21215 ^@ http://purl.uniprot.org/uniprot/G8LVK4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11580 ^@ http://purl.uniprot.org/uniprot/G8LZ12 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/720554:CLOCL_RS03520 ^@ http://purl.uniprot.org/uniprot/G8LV73 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS09995 ^@ http://purl.uniprot.org/uniprot/G8LW46 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS11570 ^@ http://purl.uniprot.org/uniprot/G8LZ10 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS09595 ^@ http://purl.uniprot.org/uniprot/G8LVI0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS19165 ^@ http://purl.uniprot.org/uniprot/G8M2J2 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/720554:CLOCL_RS13320 ^@ http://purl.uniprot.org/uniprot/G8M2C1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS14725 ^@ http://purl.uniprot.org/uniprot/G8LUB3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS13525 ^@ http://purl.uniprot.org/uniprot/G8M308 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS07740 ^@ http://purl.uniprot.org/uniprot/G8M2V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS07295 ^@ http://purl.uniprot.org/uniprot/G8M216 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/720554:CLOCL_RS05150 ^@ http://purl.uniprot.org/uniprot/G8LXM4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/720554:CLOCL_RS12620 ^@ http://purl.uniprot.org/uniprot/G8M1D9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/720554:CLOCL_RS00810 ^@ http://purl.uniprot.org/uniprot/G8M0A9 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/720554:CLOCL_RS04995 ^@ http://purl.uniprot.org/uniprot/G8LXJ4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS04485 ^@ http://purl.uniprot.org/uniprot/G8LWH6 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/720554:CLOCL_RS15330 ^@ http://purl.uniprot.org/uniprot/G8LVL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/720554:CLOCL_RS09665 ^@ http://purl.uniprot.org/uniprot/G8LVJ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/720554:CLOCL_RS12560 ^@ http://purl.uniprot.org/uniprot/G8M0R1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/720554:CLOCL_RS20015 ^@ http://purl.uniprot.org/uniprot/G8LTL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS21140 ^@ http://purl.uniprot.org/uniprot/G8M1J8 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/720554:CLOCL_RS02000 ^@ http://purl.uniprot.org/uniprot/G8M2R8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08940 ^@ http://purl.uniprot.org/uniprot/G8LU53 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/720554:CLOCL_RS08215 ^@ http://purl.uniprot.org/uniprot/G8LSJ4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/720554:CLOCL_RS14050 ^@ http://purl.uniprot.org/uniprot/G8LSR5 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS13530 ^@ http://purl.uniprot.org/uniprot/G8M309 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS05555 ^@ http://purl.uniprot.org/uniprot/G8LY81 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/720554:CLOCL_RS09620 ^@ http://purl.uniprot.org/uniprot/G8LVI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/720554:CLOCL_RS18865 ^@ http://purl.uniprot.org/uniprot/G8M2D9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS20030 ^@ http://purl.uniprot.org/uniprot/G8LTM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/720554:CLOCL_RS16625 ^@ http://purl.uniprot.org/uniprot/G8LXH4 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. http://togogenome.org/gene/720554:CLOCL_RS20130 ^@ http://purl.uniprot.org/uniprot/G8LTP1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS16660 ^@ http://purl.uniprot.org/uniprot/G8LXI2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/720554:CLOCL_RS02585 ^@ http://purl.uniprot.org/uniprot/G8LT45 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/720554:CLOCL_RS19925 ^@ http://purl.uniprot.org/uniprot/G8LSZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS06445 ^@ http://purl.uniprot.org/uniprot/G8LZR5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/720554:CLOCL_RS09845 ^@ http://purl.uniprot.org/uniprot/G8LW16 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/720554:CLOCL_RS10055 ^@ http://purl.uniprot.org/uniprot/G8LW57 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/720554:CLOCL_RS20465 ^@ http://purl.uniprot.org/uniprot/G8LUG6 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/720554:CLOCL_RS10325 ^@ http://purl.uniprot.org/uniprot/G8LWP6 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/720554:CLOCL_RS07755 ^@ http://purl.uniprot.org/uniprot/G8M2V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS21155 ^@ http://purl.uniprot.org/uniprot/G8M270 ^@ Function ^@ Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. http://togogenome.org/gene/720554:CLOCL_RS07075 ^@ http://purl.uniprot.org/uniprot/G8M1B7 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/720554:CLOCL_RS10890 ^@ http://purl.uniprot.org/uniprot/G8LXS8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/720554:CLOCL_RS11980 ^@ http://purl.uniprot.org/uniprot/G8LZU3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/720554:CLOCL_RS20470 ^@ http://purl.uniprot.org/uniprot/G8LUG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17625 ^@ http://purl.uniprot.org/uniprot/G8LZA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS15180 ^@ http://purl.uniprot.org/uniprot/G8LV48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS02425 ^@ http://purl.uniprot.org/uniprot/G8LT17 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/720554:CLOCL_RS15155 ^@ http://purl.uniprot.org/uniprot/G8LV43 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS18895 ^@ http://purl.uniprot.org/uniprot/G8M2E5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/720554:CLOCL_RS13545 ^@ http://purl.uniprot.org/uniprot/G8M312 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/720554:CLOCL_RS14000 ^@ http://purl.uniprot.org/uniprot/G8LSQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12335 ^@ http://purl.uniprot.org/uniprot/G8M0L6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/720554:CLOCL_RS11685 ^@ http://purl.uniprot.org/uniprot/G8LZ35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS13480 ^@ http://purl.uniprot.org/uniprot/G8M2Z9 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/720554:CLOCL_RS18905 ^@ http://purl.uniprot.org/uniprot/G8M2E7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/720554:CLOCL_RS16390 ^@ http://purl.uniprot.org/uniprot/G8LXD0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS10220 ^@ http://purl.uniprot.org/uniprot/G8LWM7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12900 ^@ http://purl.uniprot.org/uniprot/G8M1J0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/720554:CLOCL_RS08395 ^@ http://purl.uniprot.org/uniprot/G8LT85 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/720554:CLOCL_RS01460 ^@ http://purl.uniprot.org/uniprot/G8M1V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/720554:CLOCL_RS00295 ^@ http://purl.uniprot.org/uniprot/G8LZF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17615 ^@ http://purl.uniprot.org/uniprot/G8LZA5 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/720554:CLOCL_RS19255 ^@ http://purl.uniprot.org/uniprot/G8M360 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/720554:CLOCL_RS06815 ^@ http://purl.uniprot.org/uniprot/G8M0J3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/720554:CLOCL_RS10585 ^@ http://purl.uniprot.org/uniprot/G8LX78 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/720554:CLOCL_RS09175 ^@ http://purl.uniprot.org/uniprot/G8LUV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10670 ^@ http://purl.uniprot.org/uniprot/G8LX94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/720554:CLOCL_RS03220 ^@ http://purl.uniprot.org/uniprot/G8LUM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/720554:CLOCL_RS18940 ^@ http://purl.uniprot.org/uniprot/G8M2F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS05195 ^@ http://purl.uniprot.org/uniprot/G8LXN1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS05430 ^@ http://purl.uniprot.org/uniprot/G8LY58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06895 ^@ http://purl.uniprot.org/uniprot/G8M178 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/720554:CLOCL_RS07280 ^@ http://purl.uniprot.org/uniprot/G8M213 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16070 ^@ http://purl.uniprot.org/uniprot/G8LWT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/720554:CLOCL_RS18910 ^@ http://purl.uniprot.org/uniprot/G8M2E8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/720554:CLOCL_RS14005 ^@ http://purl.uniprot.org/uniprot/G8LSQ8 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/720554:CLOCL_RS13535 ^@ http://purl.uniprot.org/uniprot/G8M310 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/720554:CLOCL_RS05215 ^@ http://purl.uniprot.org/uniprot/G8LXN5 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/720554:CLOCL_RS18390 ^@ http://purl.uniprot.org/uniprot/G8M0W8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS13505 ^@ http://purl.uniprot.org/uniprot/G8M304 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/720554:CLOCL_RS10915 ^@ http://purl.uniprot.org/uniprot/G8LXT3 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/720554:CLOCL_RS18950 ^@ http://purl.uniprot.org/uniprot/G8M2F6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/720554:CLOCL_RS01470 ^@ http://purl.uniprot.org/uniprot/G8M1W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/720554:CLOCL_RS19615 ^@ http://purl.uniprot.org/uniprot/G8LST6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS15790 ^@ http://purl.uniprot.org/uniprot/G8LW94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS00510 ^@ http://purl.uniprot.org/uniprot/G8LZJ6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/720554:CLOCL_RS10735 ^@ http://purl.uniprot.org/uniprot/G8LXA7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/720554:CLOCL_RS20555 ^@ http://purl.uniprot.org/uniprot/G8LUI3 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/720554:CLOCL_RS20350 ^@ http://purl.uniprot.org/uniprot/G8LUE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00625 ^@ http://purl.uniprot.org/uniprot/G8M075 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/720554:CLOCL_RS18995 ^@ http://purl.uniprot.org/uniprot/G8M2G5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/720554:CLOCL_RS12305 ^@ http://purl.uniprot.org/uniprot/G8M0L0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/720554:CLOCL_RS04880 ^@ http://purl.uniprot.org/uniprot/G8LX30 ^@ Similarity ^@ Belongs to the CpsD/CapB family. http://togogenome.org/gene/720554:CLOCL_RS05610 ^@ http://purl.uniprot.org/uniprot/G8LY90 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/720554:CLOCL_RS17080 ^@ http://purl.uniprot.org/uniprot/G8LYI1 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/720554:CLOCL_RS00595 ^@ http://purl.uniprot.org/uniprot/G8M069 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/720554:CLOCL_RS15015 ^@ http://purl.uniprot.org/uniprot/G8LV18 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/720554:CLOCL_RS19000 ^@ http://purl.uniprot.org/uniprot/G8M2G6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS11950 ^@ http://purl.uniprot.org/uniprot/G8LZT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/720554:CLOCL_RS01975 ^@ http://purl.uniprot.org/uniprot/G8M2R3 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/720554:CLOCL_RS09490 ^@ http://purl.uniprot.org/uniprot/G8LVF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/720554:CLOCL_RS14645 ^@ http://purl.uniprot.org/uniprot/G8LU99 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/720554:CLOCL_RS17070 ^@ http://purl.uniprot.org/uniprot/G8LYH8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05295 ^@ http://purl.uniprot.org/uniprot/G8LXQ1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/720554:CLOCL_RS14890 ^@ http://purl.uniprot.org/uniprot/G8LUZ9 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/720554:CLOCL_RS09875 ^@ http://purl.uniprot.org/uniprot/G8LW20 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS02355 ^@ http://purl.uniprot.org/uniprot/G8LSE6 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS00565 ^@ http://purl.uniprot.org/uniprot/G8M063 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20605 ^@ http://purl.uniprot.org/uniprot/G8LUJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS06370 ^@ http://purl.uniprot.org/uniprot/G8LZQ0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/720554:CLOCL_RS07035 ^@ http://purl.uniprot.org/uniprot/G8M1A8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/720554:CLOCL_RS06475 ^@ http://purl.uniprot.org/uniprot/G8LZS1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/720554:CLOCL_RS11910 ^@ http://purl.uniprot.org/uniprot/G8LZS8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/720554:CLOCL_RS11645 ^@ http://purl.uniprot.org/uniprot/G8LZ25 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/720554:CLOCL_RS06265 ^@ http://purl.uniprot.org/uniprot/G8LZN5 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/720554:CLOCL_RS12645 ^@ http://purl.uniprot.org/uniprot/G8M1E3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS20255 ^@ http://purl.uniprot.org/uniprot/G8LTR3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS19195 ^@ http://purl.uniprot.org/uniprot/G8M2J8 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS08860 ^@ http://purl.uniprot.org/uniprot/G8LU37 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/720554:CLOCL_RS16145 ^@ http://purl.uniprot.org/uniprot/G8LWU1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS14545 ^@ http://purl.uniprot.org/uniprot/G8LU78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20670 ^@ http://purl.uniprot.org/uniprot/G8LUK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00325 ^@ http://purl.uniprot.org/uniprot/G8LZG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/720554:CLOCL_RS12710 ^@ http://purl.uniprot.org/uniprot/G8M2Y2 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS20020 ^@ http://purl.uniprot.org/uniprot/G8LTL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS08505 ^@ http://purl.uniprot.org/uniprot/G8LTA7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS12230 ^@ http://purl.uniprot.org/uniprot/G8LZY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS09520 ^@ http://purl.uniprot.org/uniprot/G8LVG5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS18255 ^@ http://purl.uniprot.org/uniprot/G8M0T8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS10365 ^@ http://purl.uniprot.org/uniprot/G8LWQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/720554:CLOCL_RS15040 ^@ http://purl.uniprot.org/uniprot/G8LV23 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/720554:CLOCL_RS00220 ^@ http://purl.uniprot.org/uniprot/G8LZE0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/720554:CLOCL_RS00745 ^@ http://purl.uniprot.org/uniprot/G8M098 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS17580 ^@ http://purl.uniprot.org/uniprot/G8LZ98 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/720554:CLOCL_RS12875 ^@ http://purl.uniprot.org/uniprot/G8M1I5 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/720554:CLOCL_RS11975 ^@ http://purl.uniprot.org/uniprot/G8LZU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/720554:CLOCL_RS05225 ^@ http://purl.uniprot.org/uniprot/G8LXN7 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/720554:CLOCL_RS16435 ^@ http://purl.uniprot.org/uniprot/G8LXE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS11835 ^@ http://purl.uniprot.org/uniprot/G8LZ62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS16810 ^@ http://purl.uniprot.org/uniprot/G8LXZ7 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS10645 ^@ http://purl.uniprot.org/uniprot/G8LX90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/720554:CLOCL_RS20225 ^@ http://purl.uniprot.org/uniprot/G8LTQ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00330 ^@ http://purl.uniprot.org/uniprot/G8LZG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/720554:CLOCL_RS17325 ^@ http://purl.uniprot.org/uniprot/G8LYM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00975 ^@ http://purl.uniprot.org/uniprot/G8M107 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/720554:CLOCL_RS13560 ^@ http://purl.uniprot.org/uniprot/G8M315 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/720554:CLOCL_RS15230 ^@ http://purl.uniprot.org/uniprot/G8LV58 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/720554:CLOCL_RS13420 ^@ http://purl.uniprot.org/uniprot/G8M2Y8 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS08930 ^@ http://purl.uniprot.org/uniprot/G8LU51 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS06990 ^@ http://purl.uniprot.org/uniprot/G8M199 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/720554:CLOCL_RS01915 ^@ http://purl.uniprot.org/uniprot/G8M2Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS01495 ^@ http://purl.uniprot.org/uniprot/G8M1W5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS10040 ^@ http://purl.uniprot.org/uniprot/G8LW54 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/720554:CLOCL_RS13600 ^@ http://purl.uniprot.org/uniprot/G8M323 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS03190 ^@ http://purl.uniprot.org/uniprot/G8LUM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/720554:CLOCL_RS12405 ^@ http://purl.uniprot.org/uniprot/G8M0N0 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/720554:CLOCL_RS08615 ^@ http://purl.uniprot.org/uniprot/G8LTC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10990 ^@ http://purl.uniprot.org/uniprot/G8LXU8 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/720554:CLOCL_RS13540 ^@ http://purl.uniprot.org/uniprot/G8M311 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/720554:CLOCL_RS17415 ^@ http://purl.uniprot.org/uniprot/G8LYP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10845 ^@ http://purl.uniprot.org/uniprot/G8LXR8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS21165 ^@ http://purl.uniprot.org/uniprot/G8M2Z1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/720554:CLOCL_RS04940 ^@ http://purl.uniprot.org/uniprot/G8LXI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS02440 ^@ http://purl.uniprot.org/uniprot/G8LT20 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS10640 ^@ http://purl.uniprot.org/uniprot/G8LX89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/720554:CLOCL_RS20245 ^@ http://purl.uniprot.org/uniprot/G8LTR1 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/720554:CLOCL_RS06485 ^@ http://purl.uniprot.org/uniprot/G8M0C9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08945 ^@ http://purl.uniprot.org/uniprot/G8LU54 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS19145 ^@ http://purl.uniprot.org/uniprot/G8M2I8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/720554:CLOCL_RS01555 ^@ http://purl.uniprot.org/uniprot/G8M1X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS17935 ^@ http://purl.uniprot.org/uniprot/G8M015 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18030 ^@ http://purl.uniprot.org/uniprot/G8M033 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS00345 ^@ http://purl.uniprot.org/uniprot/G8LZG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/720554:CLOCL_RS06225 ^@ http://purl.uniprot.org/uniprot/G8LZM7 ^@ Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/720554:CLOCL_RS10315 ^@ http://purl.uniprot.org/uniprot/G8LWP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/720554:CLOCL_RS19210 ^@ http://purl.uniprot.org/uniprot/G8M2K1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/720554:CLOCL_RS03100 ^@ http://purl.uniprot.org/uniprot/G8LUK4 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/720554:CLOCL_RS03165 ^@ http://purl.uniprot.org/uniprot/G8LUL7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/720554:CLOCL_RS05070 ^@ http://purl.uniprot.org/uniprot/G8LXK9 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/720554:CLOCL_RS09590 ^@ http://purl.uniprot.org/uniprot/G8LVH9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS17270 ^@ http://purl.uniprot.org/uniprot/G8LYL4 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/720554:CLOCL_RS05135 ^@ http://purl.uniprot.org/uniprot/G8LXM1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/720554:CLOCL_RS10275 ^@ http://purl.uniprot.org/uniprot/G8LWN8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/720554:CLOCL_RS18085 ^@ http://purl.uniprot.org/uniprot/G8M041 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/720554:CLOCL_RS08335 ^@ http://purl.uniprot.org/uniprot/G8LT73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03085 ^@ http://purl.uniprot.org/uniprot/G8LTZ5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS19185 ^@ http://purl.uniprot.org/uniprot/G8M2J6 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/720554:CLOCL_RS01370 ^@ http://purl.uniprot.org/uniprot/G8M1U0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/720554:CLOCL_RS19005 ^@ http://purl.uniprot.org/uniprot/G8M2G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/720554:CLOCL_RS19680 ^@ http://purl.uniprot.org/uniprot/G8LSU9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/720554:CLOCL_RS13695 ^@ http://purl.uniprot.org/uniprot/G8M342 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS12430 ^@ http://purl.uniprot.org/uniprot/G8M0N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/720554:CLOCL_RS01730 ^@ http://purl.uniprot.org/uniprot/G8M2L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03175 ^@ http://purl.uniprot.org/uniprot/G8LUL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/720554:CLOCL_RS00165 ^@ http://purl.uniprot.org/uniprot/G8LYS4 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/720554:CLOCL_RS08850 ^@ http://purl.uniprot.org/uniprot/G8LU35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/720554:CLOCL_RS05310 ^@ http://purl.uniprot.org/uniprot/G8LY34 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/720554:CLOCL_RS14085 ^@ http://purl.uniprot.org/uniprot/G8LSS3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/720554:CLOCL_RS09200 ^@ http://purl.uniprot.org/uniprot/G8LUW2 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/720554:CLOCL_RS18785 ^@ http://purl.uniprot.org/uniprot/G8M1R5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/720554:CLOCL_RS12000 ^@ http://purl.uniprot.org/uniprot/G8LZU7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS11245 ^@ http://purl.uniprot.org/uniprot/G8LYC9 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS14940 ^@ http://purl.uniprot.org/uniprot/G8LV06 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS05125 ^@ http://purl.uniprot.org/uniprot/G8LXL9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS07315 ^@ http://purl.uniprot.org/uniprot/G8M221 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/720554:CLOCL_RS14080 ^@ http://purl.uniprot.org/uniprot/G8LSS2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/720554:CLOCL_RS05970 ^@ http://purl.uniprot.org/uniprot/G8LYY2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/720554:CLOCL_RS09625 ^@ http://purl.uniprot.org/uniprot/G8LVI6 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/720554:CLOCL_RS13855 ^@ http://purl.uniprot.org/uniprot/G8LSM8 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/720554:CLOCL_RS16015 ^@ http://purl.uniprot.org/uniprot/G8LWS0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS09450 ^@ http://purl.uniprot.org/uniprot/G8LVF1 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/720554:CLOCL_RS06690 ^@ http://purl.uniprot.org/uniprot/G8M0G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/720554:CLOCL_RS11695 ^@ http://purl.uniprot.org/uniprot/G8LZ37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/720554:CLOCL_RS20355 ^@ http://purl.uniprot.org/uniprot/G8LUE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS07060 ^@ http://purl.uniprot.org/uniprot/G8M1B4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS03030 ^@ http://purl.uniprot.org/uniprot/G8LTY5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS06720 ^@ http://purl.uniprot.org/uniprot/G8M0H4 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/720554:CLOCL_RS18075 ^@ http://purl.uniprot.org/uniprot/G8LSK3 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS03775 ^@ http://purl.uniprot.org/uniprot/G8LVC8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/720554:CLOCL_RS18860 ^@ http://purl.uniprot.org/uniprot/G8M2D8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/720554:CLOCL_RS15030 ^@ http://purl.uniprot.org/uniprot/G8LV21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS09825 ^@ http://purl.uniprot.org/uniprot/G8LW12 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/720554:CLOCL_RS08190 ^@ http://purl.uniprot.org/uniprot/G8LSJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS13445 ^@ http://purl.uniprot.org/uniprot/G8M2Z3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS01445 ^@ http://purl.uniprot.org/uniprot/G8M1V5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS17295 ^@ http://purl.uniprot.org/uniprot/G8LYL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/720554:CLOCL_RS03665 ^@ http://purl.uniprot.org/uniprot/G8LVA4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08835 ^@ http://purl.uniprot.org/uniprot/G8LU32 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/720554:CLOCL_RS11935 ^@ http://purl.uniprot.org/uniprot/G8LZT4 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/720554:CLOCL_RS07290 ^@ http://purl.uniprot.org/uniprot/G8M215 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/720554:CLOCL_RS12970 ^@ http://purl.uniprot.org/uniprot/G8M1K4 ^@ Similarity|||Subunit ^@ Belongs to the PdxA family. PdxA2 subfamily.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS05140 ^@ http://purl.uniprot.org/uniprot/G8LXM2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 9 (cellulase E) family. http://togogenome.org/gene/720554:CLOCL_RS09305 ^@ http://purl.uniprot.org/uniprot/G8LUY0 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/720554:CLOCL_RS12515 ^@ http://purl.uniprot.org/uniprot/G8M0Q2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/720554:CLOCL_RS12745 ^@ http://purl.uniprot.org/uniprot/G8M1G3 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/720554:CLOCL_RS12505 ^@ http://purl.uniprot.org/uniprot/G8M0Q0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS20640 ^@ http://purl.uniprot.org/uniprot/G8LUJ5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/720554:CLOCL_RS12605 ^@ http://purl.uniprot.org/uniprot/G8M0S0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/720554:CLOCL_RS15390 ^@ http://purl.uniprot.org/uniprot/G8LVN1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/720554:CLOCL_RS13895 ^@ http://purl.uniprot.org/uniprot/G8LSN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16800 ^@ http://purl.uniprot.org/uniprot/G8LXZ6 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/720554:CLOCL_RS16020 ^@ http://purl.uniprot.org/uniprot/G8LWS1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/720554:CLOCL_RS03725 ^@ http://purl.uniprot.org/uniprot/G8LVB8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS08715 ^@ http://purl.uniprot.org/uniprot/G8LU08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/720554:CLOCL_RS02230 ^@ http://purl.uniprot.org/uniprot/G8LSC2 ^@ Similarity ^@ Belongs to the LOR family. http://togogenome.org/gene/720554:CLOCL_RS09315 ^@ http://purl.uniprot.org/uniprot/G8LUY2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS19600 ^@ http://purl.uniprot.org/uniprot/G8LST3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00365 ^@ http://purl.uniprot.org/uniprot/G8LZG8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/720554:CLOCL_RS08845 ^@ http://purl.uniprot.org/uniprot/G8LU34 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/720554:CLOCL_RS01570 ^@ http://purl.uniprot.org/uniprot/G8M1Y0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS09120 ^@ http://purl.uniprot.org/uniprot/G8LUU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10400 ^@ http://purl.uniprot.org/uniprot/G8LWR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14900 ^@ http://purl.uniprot.org/uniprot/G8LV00 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS18890 ^@ http://purl.uniprot.org/uniprot/G8M2E4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/720554:CLOCL_RS21015 ^@ http://purl.uniprot.org/uniprot/G8M2V8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/720554:CLOCL_RS01880 ^@ http://purl.uniprot.org/uniprot/G8M2P3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS06330 ^@ http://purl.uniprot.org/uniprot/G8LZP6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS05945 ^@ http://purl.uniprot.org/uniprot/G8LYX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LTA synthase family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08425 ^@ http://purl.uniprot.org/uniprot/G8LT91 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/720554:CLOCL_RS20490 ^@ http://purl.uniprot.org/uniprot/G8LUH0 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/720554:CLOCL_RS05230 ^@ http://purl.uniprot.org/uniprot/G8LXN8 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/720554:CLOCL_RS10710 ^@ http://purl.uniprot.org/uniprot/G8LXA2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS18755 ^@ http://purl.uniprot.org/uniprot/G8M1Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS09740 ^@ http://purl.uniprot.org/uniprot/G8LVZ3 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/720554:CLOCL_RS00320 ^@ http://purl.uniprot.org/uniprot/G8LZF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10920 ^@ http://purl.uniprot.org/uniprot/G8LXT4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/720554:CLOCL_RS19220 ^@ http://purl.uniprot.org/uniprot/G8M2K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS16740 ^@ http://purl.uniprot.org/uniprot/G8LXY4 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/720554:CLOCL_RS16570 ^@ http://purl.uniprot.org/uniprot/G8LXG3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddB/RexB type 1 subfamily.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of AddA and AddB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. http://togogenome.org/gene/720554:CLOCL_RS18870 ^@ http://purl.uniprot.org/uniprot/G8M2E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/720554:CLOCL_RS18970 ^@ http://purl.uniprot.org/uniprot/G8M2G0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/720554:CLOCL_RS12065 ^@ http://purl.uniprot.org/uniprot/G8LZW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS01095 ^@ http://purl.uniprot.org/uniprot/G8M129 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05535 ^@ http://purl.uniprot.org/uniprot/G8LY77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/720554:CLOCL_RS05560 ^@ http://purl.uniprot.org/uniprot/G8LY82 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/720554:CLOCL_RS01550 ^@ http://purl.uniprot.org/uniprot/G8M1X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/720554:CLOCL_RS19570 ^@ http://purl.uniprot.org/uniprot/G8M3C0 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/720554:CLOCL_RS02550 ^@ http://purl.uniprot.org/uniprot/G8LT38 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/720554:CLOCL_RS17880 ^@ http://purl.uniprot.org/uniprot/G8M005 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS03145 ^@ http://purl.uniprot.org/uniprot/G8LUL3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS14630 ^@ http://purl.uniprot.org/uniprot/G8LU96 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/720554:CLOCL_RS08430 ^@ http://purl.uniprot.org/uniprot/G8LT92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/720554:CLOCL_RS18925 ^@ http://purl.uniprot.org/uniprot/G8M2F1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/720554:CLOCL_RS12035 ^@ http://purl.uniprot.org/uniprot/G8LZV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/720554:CLOCL_RS08760 ^@ http://purl.uniprot.org/uniprot/G8LU17 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/720554:CLOCL_RS07080 ^@ http://purl.uniprot.org/uniprot/G8M1B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS09605 ^@ http://purl.uniprot.org/uniprot/G8LVI2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/720554:CLOCL_RS17605 ^@ http://purl.uniprot.org/uniprot/G8LZA3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS06420 ^@ http://purl.uniprot.org/uniprot/G8LZR0 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/720554:CLOCL_RS19015 ^@ http://purl.uniprot.org/uniprot/G8M2G9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/720554:CLOCL_RS19105 ^@ http://purl.uniprot.org/uniprot/G8M2I0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/720554:CLOCL_RS09790 ^@ http://purl.uniprot.org/uniprot/G8LW05 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/720554:CLOCL_RS04640 ^@ http://purl.uniprot.org/uniprot/G8LWY2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS03180 ^@ http://purl.uniprot.org/uniprot/G8LUM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/720554:CLOCL_RS10630 ^@ http://purl.uniprot.org/uniprot/G8LX87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U4 family.|||Cell membrane|||Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. http://togogenome.org/gene/720554:CLOCL_RS01960 ^@ http://purl.uniprot.org/uniprot/G8M2R0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS12855 ^@ http://purl.uniprot.org/uniprot/G8M1I1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/720554:CLOCL_RS14295 ^@ http://purl.uniprot.org/uniprot/G8LTH2 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS18915 ^@ http://purl.uniprot.org/uniprot/G8M2E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/720554:CLOCL_RS18850 ^@ http://purl.uniprot.org/uniprot/G8M1S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/720554:CLOCL_RS00585 ^@ http://purl.uniprot.org/uniprot/G8M067 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/720554:CLOCL_RS12325 ^@ http://purl.uniprot.org/uniprot/G8M0L4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/720554:CLOCL_RS10880 ^@ http://purl.uniprot.org/uniprot/G8LXS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS16470 ^@ http://purl.uniprot.org/uniprot/G8LXE7 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/720554:CLOCL_RS00880 ^@ http://purl.uniprot.org/uniprot/G8M0C2 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS19480 ^@ http://purl.uniprot.org/uniprot/G8M3A1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/720554:CLOCL_RS15775 ^@ http://purl.uniprot.org/uniprot/G8LW91 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/720554:CLOCL_RS13625 ^@ http://purl.uniprot.org/uniprot/G8M328 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/720554:CLOCL_RS16140 ^@ http://purl.uniprot.org/uniprot/G8LWU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS20415 ^@ http://purl.uniprot.org/uniprot/G8LUF7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS19450 ^@ http://purl.uniprot.org/uniprot/G8M395 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/720554:CLOCL_RS07040 ^@ http://purl.uniprot.org/uniprot/G8M1A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS04245 ^@ http://purl.uniprot.org/uniprot/G8LWD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/720554:CLOCL_RS12360 ^@ http://purl.uniprot.org/uniprot/G8M0M1 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/720554:CLOCL_RS14875 ^@ http://purl.uniprot.org/uniprot/G8LUZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/720554:CLOCL_RS10430 ^@ http://purl.uniprot.org/uniprot/G8LX46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS02890 ^@ http://purl.uniprot.org/uniprot/G8LTV9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS12910 ^@ http://purl.uniprot.org/uniprot/G8M1J2 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/720554:CLOCL_RS14170 ^@ http://purl.uniprot.org/uniprot/G8LTE7 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/720554:CLOCL_RS09390 ^@ http://purl.uniprot.org/uniprot/G8LVD9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11060 ^@ http://purl.uniprot.org/uniprot/G8LXV9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/720554:CLOCL_RS01965 ^@ http://purl.uniprot.org/uniprot/G8M2R1 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/720554:CLOCL_RS07085 ^@ http://purl.uniprot.org/uniprot/G8M1B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS10455 ^@ http://purl.uniprot.org/uniprot/G8LX52 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/720554:CLOCL_RS00525 ^@ http://purl.uniprot.org/uniprot/G8LZJ9 ^@ Function|||Similarity ^@ Belongs to the V-ATPase F subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/720554:CLOCL_RS19650 ^@ http://purl.uniprot.org/uniprot/G8LSU3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08140 ^@ http://purl.uniprot.org/uniprot/G8LSI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/720554:CLOCL_RS04575 ^@ http://purl.uniprot.org/uniprot/G8LWJ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS17570 ^@ http://purl.uniprot.org/uniprot/G8LZ96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/720554:CLOCL_RS13890 ^@ http://purl.uniprot.org/uniprot/G8LSN5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS18475 ^@ http://purl.uniprot.org/uniprot/G8M0Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10720 ^@ http://purl.uniprot.org/uniprot/G8LXA4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/720554:CLOCL_RS16055 ^@ http://purl.uniprot.org/uniprot/G8LWS8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS01440 ^@ http://purl.uniprot.org/uniprot/G8M1V4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16045 ^@ http://purl.uniprot.org/uniprot/G8LWS6 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/720554:CLOCL_RS09485 ^@ http://purl.uniprot.org/uniprot/G8LVF8 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/720554:CLOCL_RS09270 ^@ http://purl.uniprot.org/uniprot/G8LUX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/720554:CLOCL_RS08990 ^@ http://purl.uniprot.org/uniprot/G8LU64 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/720554:CLOCL_RS20060 ^@ http://purl.uniprot.org/uniprot/G8LTM6 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/720554:CLOCL_RS10070 ^@ http://purl.uniprot.org/uniprot/G8LW60 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/720554:CLOCL_RS08510 ^@ http://purl.uniprot.org/uniprot/G8LTA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/720554:CLOCL_RS15115 ^@ http://purl.uniprot.org/uniprot/G8LV35 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/720554:CLOCL_RS00370 ^@ http://purl.uniprot.org/uniprot/G8LZG9 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/720554:CLOCL_RS20040 ^@ http://purl.uniprot.org/uniprot/G8LTM2 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/720554:CLOCL_RS18955 ^@ http://purl.uniprot.org/uniprot/G8M2F7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/720554:CLOCL_RS09005 ^@ http://purl.uniprot.org/uniprot/G8LU67 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/720554:CLOCL_RS17760 ^@ http://purl.uniprot.org/uniprot/G8LZD0 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/720554:CLOCL_RS02050 ^@ http://purl.uniprot.org/uniprot/G8LS91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS07195 ^@ http://purl.uniprot.org/uniprot/G8M1Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/720554:CLOCL_RS16365 ^@ http://purl.uniprot.org/uniprot/G8LXC5 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/720554:CLOCL_RS11920 ^@ http://purl.uniprot.org/uniprot/G8LZT0 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 51 family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/720554:CLOCL_RS06725 ^@ http://purl.uniprot.org/uniprot/G8M0H5 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS01760 ^@ http://purl.uniprot.org/uniprot/G8M2M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS12320 ^@ http://purl.uniprot.org/uniprot/G8M0L3 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/720554:CLOCL_RS00340 ^@ http://purl.uniprot.org/uniprot/G8LZG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/720554:CLOCL_RS02415 ^@ http://purl.uniprot.org/uniprot/G8LT15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/720554:CLOCL_RS12015 ^@ http://purl.uniprot.org/uniprot/G8LZV0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS09615 ^@ http://purl.uniprot.org/uniprot/G8LVI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS09155 ^@ http://purl.uniprot.org/uniprot/G8LUV4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS08960 ^@ http://purl.uniprot.org/uniprot/G8LU57 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08460 ^@ http://purl.uniprot.org/uniprot/G8LT98 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/720554:CLOCL_RS15245 ^@ http://purl.uniprot.org/uniprot/G8LV61 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS03140 ^@ http://purl.uniprot.org/uniprot/G8LUL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10870 ^@ http://purl.uniprot.org/uniprot/G8LXS4 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS00610 ^@ http://purl.uniprot.org/uniprot/G8M072 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/720554:CLOCL_RS03265 ^@ http://purl.uniprot.org/uniprot/G8LUN7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/720554:CLOCL_RS18980 ^@ http://purl.uniprot.org/uniprot/G8M2G2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS20380 ^@ http://purl.uniprot.org/uniprot/G8LUF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/720554:CLOCL_RS08495 ^@ http://purl.uniprot.org/uniprot/G8LTA5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/720554:CLOCL_RS19620 ^@ http://purl.uniprot.org/uniprot/G8LST7 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/720554:CLOCL_RS12270 ^@ http://purl.uniprot.org/uniprot/G8M0K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11650 ^@ http://purl.uniprot.org/uniprot/G8LZ26 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/720554:CLOCL_RS09205 ^@ http://purl.uniprot.org/uniprot/G8LUW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS13655 ^@ http://purl.uniprot.org/uniprot/G8M334 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/720554:CLOCL_RS12925 ^@ http://purl.uniprot.org/uniprot/G8M1J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS10620 ^@ http://purl.uniprot.org/uniprot/G8LX85 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS03155 ^@ http://purl.uniprot.org/uniprot/G8LUL5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/720554:CLOCL_RS19035 ^@ http://purl.uniprot.org/uniprot/G8M2H3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/720554:CLOCL_RS09260 ^@ http://purl.uniprot.org/uniprot/G8LUX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS01920 ^@ http://purl.uniprot.org/uniprot/G8M2Q1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/720554:CLOCL_RS19200 ^@ http://purl.uniprot.org/uniprot/G8M2J9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/720554:CLOCL_RS20645 ^@ http://purl.uniprot.org/uniprot/G8LUJ6 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/720554:CLOCL_RS05245 ^@ http://purl.uniprot.org/uniprot/G8LXP1 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/720554:CLOCL_RS03225 ^@ http://purl.uniprot.org/uniprot/G8LUM9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS09575 ^@ http://purl.uniprot.org/uniprot/G8LVH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12795 ^@ http://purl.uniprot.org/uniprot/G8M1G9 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/720554:CLOCL_RS17200 ^@ http://purl.uniprot.org/uniprot/G8LYK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11215 ^@ http://purl.uniprot.org/uniprot/G8LYC3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/720554:CLOCL_RS08265 ^@ http://purl.uniprot.org/uniprot/G8LSK3 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS15565 ^@ http://purl.uniprot.org/uniprot/G8LVR1 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS16135 ^@ http://purl.uniprot.org/uniprot/G8LWT9 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS02530 ^@ http://purl.uniprot.org/uniprot/G8LT35 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS00360 ^@ http://purl.uniprot.org/uniprot/G8LZG7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS18855 ^@ http://purl.uniprot.org/uniprot/G8M2D7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08100 ^@ http://purl.uniprot.org/uniprot/G8LSH4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS08290 ^@ http://purl.uniprot.org/uniprot/G8LSK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/720554:CLOCL_RS16345 ^@ http://purl.uniprot.org/uniprot/G8LXC0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS18930 ^@ http://purl.uniprot.org/uniprot/G8M2F2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS05415 ^@ http://purl.uniprot.org/uniprot/G8LY55 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/720554:CLOCL_RS14120 ^@ http://purl.uniprot.org/uniprot/G8LST0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS19830 ^@ http://purl.uniprot.org/uniprot/G8LSX9 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).|||Homodimer.|||In the C-terminal section; belongs to the MurCDEF family. http://togogenome.org/gene/720554:CLOCL_RS01530 ^@ http://purl.uniprot.org/uniprot/G8M1X2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS00755 ^@ http://purl.uniprot.org/uniprot/G8M0A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10415 ^@ http://purl.uniprot.org/uniprot/G8LX43 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/720554:CLOCL_RS15545 ^@ http://purl.uniprot.org/uniprot/G8LSG1 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/720554:CLOCL_RS04620 ^@ http://purl.uniprot.org/uniprot/G8LWX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/720554:CLOCL_RS19520 ^@ http://purl.uniprot.org/uniprot/G8M3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS07055 ^@ http://purl.uniprot.org/uniprot/G8M1B3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS03230 ^@ http://purl.uniprot.org/uniprot/G8LUN0 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/720554:CLOCL_RS17385 ^@ http://purl.uniprot.org/uniprot/G8LYN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS06195 ^@ http://purl.uniprot.org/uniprot/G8LZM1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/720554:CLOCL_RS09410 ^@ http://purl.uniprot.org/uniprot/G8LVE3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS02375 ^@ http://purl.uniprot.org/uniprot/G8LT07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS08595 ^@ http://purl.uniprot.org/uniprot/G8LTC5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/720554:CLOCL_RS04725 ^@ http://purl.uniprot.org/uniprot/G8LWZ9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/720554:CLOCL_RS11970 ^@ http://purl.uniprot.org/uniprot/G8LZU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/720554:CLOCL_RS13500 ^@ http://purl.uniprot.org/uniprot/G8M303 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/720554:CLOCL_RS18650 ^@ http://purl.uniprot.org/uniprot/G8M1N9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS06165 ^@ http://purl.uniprot.org/uniprot/G8LZL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/720554:CLOCL_RS14205 ^@ http://purl.uniprot.org/uniprot/G8LTF4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/720554:CLOCL_RS03170 ^@ http://purl.uniprot.org/uniprot/G8LUL8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/720554:CLOCL_RS02740 ^@ http://purl.uniprot.org/uniprot/G8LTS9 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/720554:CLOCL_RS15235 ^@ http://purl.uniprot.org/uniprot/G8LV59 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/720554:CLOCL_RS14055 ^@ http://purl.uniprot.org/uniprot/G8LSR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/720554:CLOCL_RS03185 ^@ http://purl.uniprot.org/uniprot/G8LUM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/720554:CLOCL_RS05525 ^@ http://purl.uniprot.org/uniprot/G8LY75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS15370 ^@ http://purl.uniprot.org/uniprot/G8LVM7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS03070 ^@ http://purl.uniprot.org/uniprot/G8LTZ3 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/720554:CLOCL_RS05445 ^@ http://purl.uniprot.org/uniprot/G8LY61 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/720554:CLOCL_RS04505 ^@ http://purl.uniprot.org/uniprot/G8LWI0 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS20205 ^@ http://purl.uniprot.org/uniprot/G8LTQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/720554:CLOCL_RS20455 ^@ http://purl.uniprot.org/uniprot/G8LUG4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/720554:CLOCL_RS18130 ^@ http://purl.uniprot.org/uniprot/G8M049 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS12295 ^@ http://purl.uniprot.org/uniprot/G8M0K8 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/720554:CLOCL_RS17595 ^@ http://purl.uniprot.org/uniprot/G8LZA1 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/720554:CLOCL_RS14060 ^@ http://purl.uniprot.org/uniprot/G8LSR7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS05765 ^@ http://purl.uniprot.org/uniprot/G8LYU3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS09495 ^@ http://purl.uniprot.org/uniprot/G8LVG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/720554:CLOCL_RS05815 ^@ http://purl.uniprot.org/uniprot/G8LYV2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/720554:CLOCL_RS01055 ^@ http://purl.uniprot.org/uniprot/G8M121 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05220 ^@ http://purl.uniprot.org/uniprot/G8LXN6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS11015 ^@ http://purl.uniprot.org/uniprot/G8LXV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/720554:CLOCL_RS19670 ^@ http://purl.uniprot.org/uniprot/G8LSU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS06220 ^@ http://purl.uniprot.org/uniprot/G8LZM6 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/720554:CLOCL_RS00535 ^@ http://purl.uniprot.org/uniprot/G8LZK1 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/720554:CLOCL_RS07320 ^@ http://purl.uniprot.org/uniprot/G8M222 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/720554:CLOCL_RS02515 ^@ http://purl.uniprot.org/uniprot/G8LT32 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/720554:CLOCL_RS12170 ^@ http://purl.uniprot.org/uniprot/G8LWJ3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS02965 ^@ http://purl.uniprot.org/uniprot/G8LTX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS06685 ^@ http://purl.uniprot.org/uniprot/G8M0G8 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/720554:CLOCL_RS03640 ^@ http://purl.uniprot.org/uniprot/G8LV98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05860 ^@ http://purl.uniprot.org/uniprot/G8LYW0 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/720554:CLOCL_RS20045 ^@ http://purl.uniprot.org/uniprot/G8LTM3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS08970 ^@ http://purl.uniprot.org/uniprot/G8LU59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/720554:CLOCL_RS04800 ^@ http://purl.uniprot.org/uniprot/G8LX14 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/720554:CLOCL_RS13485 ^@ http://purl.uniprot.org/uniprot/G8M300 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS19730 ^@ http://purl.uniprot.org/uniprot/G8LSV9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS06535 ^@ http://purl.uniprot.org/uniprot/G8M0D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/720554:CLOCL_RS06785 ^@ http://purl.uniprot.org/uniprot/G8M0I7 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/720554:CLOCL_RS13755 ^@ http://purl.uniprot.org/uniprot/G8M351 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18495 ^@ http://purl.uniprot.org/uniprot/G8M0Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12105 ^@ http://purl.uniprot.org/uniprot/G8LZW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS05315 ^@ http://purl.uniprot.org/uniprot/G8LY35 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/720554:CLOCL_RS08110 ^@ http://purl.uniprot.org/uniprot/G8LSH6 ^@ Similarity ^@ Belongs to the radical SAM superfamily. NifB family. http://togogenome.org/gene/720554:CLOCL_RS12030 ^@ http://purl.uniprot.org/uniprot/G8LZV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS11600 ^@ http://purl.uniprot.org/uniprot/G8LZ16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/720554:CLOCL_RS09505 ^@ http://purl.uniprot.org/uniprot/G8LVG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/720554:CLOCL_RS09640 ^@ http://purl.uniprot.org/uniprot/G8LVI9 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/720554:CLOCL_RS11640 ^@ http://purl.uniprot.org/uniprot/G8LZ24 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS03285 ^@ http://purl.uniprot.org/uniprot/G8LUP1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/720554:CLOCL_RS05625 ^@ http://purl.uniprot.org/uniprot/G8LY93 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS04685 ^@ http://purl.uniprot.org/uniprot/G8LWZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/720554:CLOCL_RS15170 ^@ http://purl.uniprot.org/uniprot/G8LV46 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/720554:CLOCL_RS05450 ^@ http://purl.uniprot.org/uniprot/G8LY62 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/720554:CLOCL_RS09280 ^@ http://purl.uniprot.org/uniprot/G8LUX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/720554:CLOCL_RS17125 ^@ http://purl.uniprot.org/uniprot/G8LYJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer. http://togogenome.org/gene/720554:CLOCL_RS17285 ^@ http://purl.uniprot.org/uniprot/G8LYL7 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/720554:CLOCL_RS02640 ^@ http://purl.uniprot.org/uniprot/G8LT55 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/720554:CLOCL_RS12500 ^@ http://purl.uniprot.org/uniprot/G8M0P9 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/720554:CLOCL_RS06840 ^@ http://purl.uniprot.org/uniprot/G8M0J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08455 ^@ http://purl.uniprot.org/uniprot/G8LT97 ^@ Function|||Subunit ^@ Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/720554:CLOCL_RS03670 ^@ http://purl.uniprot.org/uniprot/G8LVA5 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/720554:CLOCL_RS13630 ^@ http://purl.uniprot.org/uniprot/G8M329 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS17895 ^@ http://purl.uniprot.org/uniprot/G8M007 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS16025 ^@ http://purl.uniprot.org/uniprot/G8LWS2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS09330 ^@ http://purl.uniprot.org/uniprot/G8LUY5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS19455 ^@ http://purl.uniprot.org/uniprot/G8M396 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS19110 ^@ http://purl.uniprot.org/uniprot/G8M2I1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS00600 ^@ http://purl.uniprot.org/uniprot/G8M070 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/720554:CLOCL_RS12840 ^@ http://purl.uniprot.org/uniprot/G8M1H8 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/720554:CLOCL_RS10205 ^@ http://purl.uniprot.org/uniprot/G8LWM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS04630 ^@ http://purl.uniprot.org/uniprot/G8LWY0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03115 ^@ http://purl.uniprot.org/uniprot/G8LUK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS19180 ^@ http://purl.uniprot.org/uniprot/G8M2J5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/720554:CLOCL_RS18380 ^@ http://purl.uniprot.org/uniprot/G8M0W6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS01575 ^@ http://purl.uniprot.org/uniprot/G8M1Y1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/720554:CLOCL_RS17405 ^@ http://purl.uniprot.org/uniprot/G8LYN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS17550 ^@ http://purl.uniprot.org/uniprot/G8LZ92 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/720554:CLOCL_RS02905 ^@ http://purl.uniprot.org/uniprot/G8LTW2 ^@ Similarity ^@ Belongs to the SleB family. http://togogenome.org/gene/720554:CLOCL_RS03290 ^@ http://purl.uniprot.org/uniprot/G8LUP2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/720554:CLOCL_RS17575 ^@ http://purl.uniprot.org/uniprot/G8LZ97 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS01990 ^@ http://purl.uniprot.org/uniprot/G8M2R6 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.|||Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. http://togogenome.org/gene/720554:CLOCL_RS10865 ^@ http://purl.uniprot.org/uniprot/G8LXS3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/720554:CLOCL_RS19280 ^@ http://purl.uniprot.org/uniprot/G8M365 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/720554:CLOCL_RS01430 ^@ http://purl.uniprot.org/uniprot/G8M1V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS02380 ^@ http://purl.uniprot.org/uniprot/G8LT08 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/720554:CLOCL_RS09000 ^@ http://purl.uniprot.org/uniprot/G8LU66 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/720554:CLOCL_RS04895 ^@ http://purl.uniprot.org/uniprot/G8LX33 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/720554:CLOCL_RS08330 ^@ http://purl.uniprot.org/uniprot/G8LT72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/720554:CLOCL_RS00655 ^@ http://purl.uniprot.org/uniprot/G8M082 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/720554:CLOCL_RS08545 ^@ http://purl.uniprot.org/uniprot/G8LTB5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS05605 ^@ http://purl.uniprot.org/uniprot/G8LY89 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS11575 ^@ http://purl.uniprot.org/uniprot/G8LZ11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/720554:CLOCL_RS20250 ^@ http://purl.uniprot.org/uniprot/G8LTR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/720554:CLOCL_RS14510 ^@ http://purl.uniprot.org/uniprot/G8M2Y2 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS19260 ^@ http://purl.uniprot.org/uniprot/G8M361 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/720554:CLOCL_RS17885 ^@ http://purl.uniprot.org/uniprot/G8M005 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS07105 ^@ http://purl.uniprot.org/uniprot/G8M1C3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS15575 ^@ http://purl.uniprot.org/uniprot/G8LVR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00815 ^@ http://purl.uniprot.org/uniprot/G8M0B0 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/720554:CLOCL_RS09525 ^@ http://purl.uniprot.org/uniprot/G8LVG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12050 ^@ http://purl.uniprot.org/uniprot/G8LZV7 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/720554:CLOCL_RS00260 ^@ http://purl.uniprot.org/uniprot/G8LZE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS19405 ^@ http://purl.uniprot.org/uniprot/G8M388 ^@ Function|||Similarity ^@ Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/720554:CLOCL_RS00070 ^@ http://purl.uniprot.org/uniprot/G8LYQ4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14045 ^@ http://purl.uniprot.org/uniprot/G8LSR4 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/720554:CLOCL_RS04190 ^@ http://purl.uniprot.org/uniprot/G8LVY5 ^@ Similarity ^@ Belongs to the aromatic prenyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS04415 ^@ http://purl.uniprot.org/uniprot/G8LWG3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/720554:CLOCL_RS17515 ^@ http://purl.uniprot.org/uniprot/G8LZ85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14750 ^@ http://purl.uniprot.org/uniprot/G8LUB8 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/720554:CLOCL_RS05435 ^@ http://purl.uniprot.org/uniprot/G8LY59 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/720554:CLOCL_RS19760 ^@ http://purl.uniprot.org/uniprot/G8LSW5 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/720554:CLOCL_RS02360 ^@ http://purl.uniprot.org/uniprot/G8LT04 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/720554:CLOCL_RS03805 ^@ http://purl.uniprot.org/uniprot/G8LVD4 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/720554:CLOCL_RS17525 ^@ http://purl.uniprot.org/uniprot/G8LZ87 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/720554:CLOCL_RS05100 ^@ http://purl.uniprot.org/uniprot/G8LXL4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS06000 ^@ http://purl.uniprot.org/uniprot/G8LYY8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS14795 ^@ http://purl.uniprot.org/uniprot/G8LUC6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/720554:CLOCL_RS15225 ^@ http://purl.uniprot.org/uniprot/G8LV57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12330 ^@ http://purl.uniprot.org/uniprot/G8M0L5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/720554:CLOCL_RS16475 ^@ http://purl.uniprot.org/uniprot/G8LXE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS20155 ^@ http://purl.uniprot.org/uniprot/G8LTP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11120 ^@ http://purl.uniprot.org/uniprot/G8LYA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS13865 ^@ http://purl.uniprot.org/uniprot/G8LSN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpsD/CapB family.|||Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12440 ^@ http://purl.uniprot.org/uniprot/G8M0N7 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/720554:CLOCL_RS09795 ^@ http://purl.uniprot.org/uniprot/G8LW06 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/720554:CLOCL_RS01585 ^@ http://purl.uniprot.org/uniprot/G8M1Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/720554:CLOCL_RS14150 ^@ http://purl.uniprot.org/uniprot/G8LTE3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS04515 ^@ http://purl.uniprot.org/uniprot/G8LWI2 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 67 family.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS19095 ^@ http://purl.uniprot.org/uniprot/G8M2H8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/720554:CLOCL_RS13850 ^@ http://purl.uniprot.org/uniprot/G8LSM7 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/720554:CLOCL_RS02955 ^@ http://purl.uniprot.org/uniprot/G8LTX1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/720554:CLOCL_RS04930 ^@ http://purl.uniprot.org/uniprot/G8LX40 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS11620 ^@ http://purl.uniprot.org/uniprot/G8LZ20 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/720554:CLOCL_RS04365 ^@ http://purl.uniprot.org/uniprot/G8LWF3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/720554:CLOCL_RS04230 ^@ http://purl.uniprot.org/uniprot/G8LWD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05900 ^@ http://purl.uniprot.org/uniprot/G8LYW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/720554:CLOCL_RS18500 ^@ http://purl.uniprot.org/uniprot/G8M0Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS02280 ^@ http://purl.uniprot.org/uniprot/G8LSD2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS20265 ^@ http://purl.uniprot.org/uniprot/G8LTR5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/720554:CLOCL_RS16720 ^@ http://purl.uniprot.org/uniprot/G8LXY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/720554:CLOCL_RS08035 ^@ http://purl.uniprot.org/uniprot/G8LSG1 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/720554:CLOCL_RS04405 ^@ http://purl.uniprot.org/uniprot/G8LWG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20525 ^@ http://purl.uniprot.org/uniprot/G8LUH7 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/720554:CLOCL_RS21105 ^@ http://purl.uniprot.org/uniprot/G8LZ66 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/720554:CLOCL_RS12540 ^@ http://purl.uniprot.org/uniprot/G8M0Q7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusB family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/720554:CLOCL_RS19040 ^@ http://purl.uniprot.org/uniprot/G8M2H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS06890 ^@ http://purl.uniprot.org/uniprot/G8M177 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS07910 ^@ http://purl.uniprot.org/uniprot/G8M2Y2 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS10065 ^@ http://purl.uniprot.org/uniprot/G8LW59 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/720554:CLOCL_RS19510 ^@ http://purl.uniprot.org/uniprot/G8M3A8 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/720554:CLOCL_RS05495 ^@ http://purl.uniprot.org/uniprot/G8LY71 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/720554:CLOCL_RS11605 ^@ http://purl.uniprot.org/uniprot/G8LZ17 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS17535 ^@ http://purl.uniprot.org/uniprot/G8LZ89 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/720554:CLOCL_RS15785 ^@ http://purl.uniprot.org/uniprot/G8LW93 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/720554:CLOCL_RS10435 ^@ http://purl.uniprot.org/uniprot/G8LX47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS02885 ^@ http://purl.uniprot.org/uniprot/G8LTV8 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family. http://togogenome.org/gene/720554:CLOCL_RS19275 ^@ http://purl.uniprot.org/uniprot/G8M364 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS07045 ^@ http://purl.uniprot.org/uniprot/G8M1B1 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/720554:CLOCL_RS11705 ^@ http://purl.uniprot.org/uniprot/G8LZ39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/720554:CLOCL_RS08610 ^@ http://purl.uniprot.org/uniprot/G8LTC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10225 ^@ http://purl.uniprot.org/uniprot/G8LWM8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS04955 ^@ http://purl.uniprot.org/uniprot/G8LXI6 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/720554:CLOCL_RS16575 ^@ http://purl.uniprot.org/uniprot/G8LXG4 ^@ Similarity ^@ Belongs to the peptidase A8 family. http://togogenome.org/gene/720554:CLOCL_RS14785 ^@ http://purl.uniprot.org/uniprot/G8LUC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/720554:CLOCL_RS10960 ^@ http://purl.uniprot.org/uniprot/G8LXU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS10165 ^@ http://purl.uniprot.org/uniprot/G8LWL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14960 ^@ http://purl.uniprot.org/uniprot/G8LV10 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/720554:CLOCL_RS10355 ^@ http://purl.uniprot.org/uniprot/G8LWQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/720554:CLOCL_RS00660 ^@ http://purl.uniprot.org/uniprot/G8M083 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/720554:CLOCL_RS16455 ^@ http://purl.uniprot.org/uniprot/G8LXE4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS13965 ^@ http://purl.uniprot.org/uniprot/G8LSQ0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/720554:CLOCL_RS01950 ^@ http://purl.uniprot.org/uniprot/G8M2Q8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS05985 ^@ http://purl.uniprot.org/uniprot/G8LYY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/720554:CLOCL_RS10665 ^@ http://purl.uniprot.org/uniprot/G8LX93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/720554:CLOCL_RS05530 ^@ http://purl.uniprot.org/uniprot/G8LY76 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/720554:CLOCL_RS11560 ^@ http://purl.uniprot.org/uniprot/G8LZ08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS18370 ^@ http://purl.uniprot.org/uniprot/G8M0W4 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/720554:CLOCL_RS01520 ^@ http://purl.uniprot.org/uniprot/G8M1X0 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/720554:CLOCL_RS14835 ^@ http://purl.uniprot.org/uniprot/G8LUD4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/720554:CLOCL_RS19835 ^@ http://purl.uniprot.org/uniprot/G8LSY0 ^@ Function|||Similarity ^@ Belongs to the peptidase S51 family.|||Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. http://togogenome.org/gene/720554:CLOCL_RS08900 ^@ http://purl.uniprot.org/uniprot/G8LU45 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/720554:CLOCL_RS01395 ^@ http://purl.uniprot.org/uniprot/G8M1U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/720554:CLOCL_RS19770 ^@ http://purl.uniprot.org/uniprot/G8LSW7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/720554:CLOCL_RS05325 ^@ http://purl.uniprot.org/uniprot/G8LY37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS02745 ^@ http://purl.uniprot.org/uniprot/G8LTT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.|||Homooctamer.|||Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. http://togogenome.org/gene/720554:CLOCL_RS06205 ^@ http://purl.uniprot.org/uniprot/G8LZM3 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Belongs to the radical SAM superfamily. NifB family.|||Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster. http://togogenome.org/gene/720554:CLOCL_RS18570 ^@ http://purl.uniprot.org/uniprot/G8M1L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00375 ^@ http://purl.uniprot.org/uniprot/G8LZH0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/720554:CLOCL_RS10840 ^@ http://purl.uniprot.org/uniprot/G8LXR7 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/720554:CLOCL_RS18470 ^@ http://purl.uniprot.org/uniprot/G8M0Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06620 ^@ http://purl.uniprot.org/uniprot/G8M0F5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS16640 ^@ http://purl.uniprot.org/uniprot/G8LXH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS09630 ^@ http://purl.uniprot.org/uniprot/G8LVI7 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/720554:CLOCL_RS04520 ^@ http://purl.uniprot.org/uniprot/G8LWI4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/720554:CLOCL_RS10760 ^@ http://purl.uniprot.org/uniprot/G8LXB2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS00605 ^@ http://purl.uniprot.org/uniprot/G8M071 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS15920 ^@ http://purl.uniprot.org/uniprot/G8LWC0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/720554:CLOCL_RS16195 ^@ http://purl.uniprot.org/uniprot/G8LWV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS03655 ^@ http://purl.uniprot.org/uniprot/G8LVA1 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/720554:CLOCL_RS14140 ^@ http://purl.uniprot.org/uniprot/G8LTE1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS13665 ^@ http://purl.uniprot.org/uniprot/G8M336 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16610 ^@ http://purl.uniprot.org/uniprot/G8LXH1 ^@ Caution|||Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Belongs to the MsrB Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|||In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.|||In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS03150 ^@ http://purl.uniprot.org/uniprot/G8LUL4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/720554:CLOCL_RS14730 ^@ http://purl.uniprot.org/uniprot/G8LUB4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/720554:CLOCL_RS04790 ^@ http://purl.uniprot.org/uniprot/G8LX12 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/720554:CLOCL_RS14225 ^@ http://purl.uniprot.org/uniprot/G8LTF8 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/720554:CLOCL_RS17475 ^@ http://purl.uniprot.org/uniprot/G8LZ78 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/720554:CLOCL_RS14580 ^@ http://purl.uniprot.org/uniprot/G8LU86 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS13390 ^@ http://purl.uniprot.org/uniprot/G8M2D3 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/720554:CLOCL_RS13440 ^@ http://purl.uniprot.org/uniprot/G8M2Z2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11565 ^@ http://purl.uniprot.org/uniprot/G8LZ09 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/720554:CLOCL_RS13590 ^@ http://purl.uniprot.org/uniprot/G8M321 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/720554:CLOCL_RS00145 ^@ http://purl.uniprot.org/uniprot/G8LYR9 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/720554:CLOCL_RS05145 ^@ http://purl.uniprot.org/uniprot/G8LXM3 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/720554:CLOCL_RS07275 ^@ http://purl.uniprot.org/uniprot/G8M212 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/720554:CLOCL_RS17905 ^@ http://purl.uniprot.org/uniprot/G8M009 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS06680 ^@ http://purl.uniprot.org/uniprot/G8M0G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/720554:CLOCL_RS02785 ^@ http://purl.uniprot.org/uniprot/G8LTT8 ^@ Similarity ^@ Belongs to the IspF family. http://togogenome.org/gene/720554:CLOCL_RS19175 ^@ http://purl.uniprot.org/uniprot/G8M2J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS12390 ^@ http://purl.uniprot.org/uniprot/G8M0M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS16985 ^@ http://purl.uniprot.org/uniprot/G8LY22 ^@ Similarity ^@ Belongs to the transposase IS21/IS408/IS1162 family. http://togogenome.org/gene/720554:CLOCL_RS09125 ^@ http://purl.uniprot.org/uniprot/G8LUU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS02210 ^@ http://purl.uniprot.org/uniprot/G8LSB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS01905 ^@ http://purl.uniprot.org/uniprot/G8M2P8 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/720554:CLOCL_RS14685 ^@ http://purl.uniprot.org/uniprot/G8LUA8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/720554:CLOCL_RS05550 ^@ http://purl.uniprot.org/uniprot/G8LY80 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/720554:CLOCL_RS02860 ^@ http://purl.uniprot.org/uniprot/G8LTV2 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/720554:CLOCL_RS08755 ^@ http://purl.uniprot.org/uniprot/G8LU16 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/720554:CLOCL_RS01765 ^@ http://purl.uniprot.org/uniprot/G8M2M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS03845 ^@ http://purl.uniprot.org/uniprot/G8LVT0 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/720554:CLOCL_RS12965 ^@ http://purl.uniprot.org/uniprot/G8M1K3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/720554:CLOCL_RS03035 ^@ http://purl.uniprot.org/uniprot/G8LTY6 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/720554:CLOCL_RS17490 ^@ http://purl.uniprot.org/uniprot/G8LZ81 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS09815 ^@ http://purl.uniprot.org/uniprot/G8LW10 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/720554:CLOCL_RS00005 ^@ http://purl.uniprot.org/uniprot/G8LYP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/720554:CLOCL_RS14840 ^@ http://purl.uniprot.org/uniprot/G8LUD5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/720554:CLOCL_RS02845 ^@ http://purl.uniprot.org/uniprot/G8LTU9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/720554:CLOCL_RS08855 ^@ http://purl.uniprot.org/uniprot/G8LU36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS04745 ^@ http://purl.uniprot.org/uniprot/G8LX03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS04530 ^@ http://purl.uniprot.org/uniprot/G8LWI6 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/720554:CLOCL_RS08765 ^@ http://purl.uniprot.org/uniprot/G8LU18 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/720554:CLOCL_RS11795 ^@ http://purl.uniprot.org/uniprot/G8LZ54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/720554:CLOCL_RS00560 ^@ http://purl.uniprot.org/uniprot/G8M062 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS16305 ^@ http://purl.uniprot.org/uniprot/G8LWW9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/720554:CLOCL_RS06435 ^@ http://purl.uniprot.org/uniprot/G8LZR3 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/720554:CLOCL_RS09840 ^@ http://purl.uniprot.org/uniprot/G8LW15 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/720554:CLOCL_RS04855 ^@ http://purl.uniprot.org/uniprot/G8LX25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03205 ^@ http://purl.uniprot.org/uniprot/G8LUM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/720554:CLOCL_RS04910 ^@ http://purl.uniprot.org/uniprot/G8LX36 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/720554:CLOCL_RS07110 ^@ http://purl.uniprot.org/uniprot/G8M1C4 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/720554:CLOCL_RS17620 ^@ http://purl.uniprot.org/uniprot/G8LZA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/720554:CLOCL_RS04195 ^@ http://purl.uniprot.org/uniprot/G8LVY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/720554:CLOCL_RS13810 ^@ http://purl.uniprot.org/uniprot/G8LSL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16465 ^@ http://purl.uniprot.org/uniprot/G8LXE6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS19020 ^@ http://purl.uniprot.org/uniprot/G8M2H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/720554:CLOCL_RS11170 ^@ http://purl.uniprot.org/uniprot/G8LYB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS09225 ^@ http://purl.uniprot.org/uniprot/G8LUW7 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/720554:CLOCL_RS15955 ^@ http://purl.uniprot.org/uniprot/G8LWC7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/720554:CLOCL_RS01745 ^@ http://purl.uniprot.org/uniprot/G8M2M1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS20305 ^@ http://purl.uniprot.org/uniprot/G8LTS4 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/720554:CLOCL_RS01910 ^@ http://purl.uniprot.org/uniprot/G8M2P9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/720554:CLOCL_RS11820 ^@ http://purl.uniprot.org/uniprot/G8LZ59 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/720554:CLOCL_RS13760 ^@ http://purl.uniprot.org/uniprot/G8M352 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18965 ^@ http://purl.uniprot.org/uniprot/G8M2F9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/720554:CLOCL_RS11730 ^@ http://purl.uniprot.org/uniprot/G8LZ43 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/720554:CLOCL_RS09530 ^@ http://purl.uniprot.org/uniprot/G8LVG7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS18020 ^@ http://purl.uniprot.org/uniprot/G8M031 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18845 ^@ http://purl.uniprot.org/uniprot/G8M1S6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/720554:CLOCL_RS08500 ^@ http://purl.uniprot.org/uniprot/G8LTA6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/720554:CLOCL_RS17795 ^@ http://purl.uniprot.org/uniprot/G8LZZ2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS02495 ^@ http://purl.uniprot.org/uniprot/G8LT27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/720554:CLOCL_RS12960 ^@ http://purl.uniprot.org/uniprot/G8M1K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/720554:CLOCL_RS15320 ^@ http://purl.uniprot.org/uniprot/G8LVL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/720554:CLOCL_RS06630 ^@ http://purl.uniprot.org/uniprot/G8M0F7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/720554:CLOCL_RS01565 ^@ http://purl.uniprot.org/uniprot/G8M1X9 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/720554:CLOCL_RS13915 ^@ http://purl.uniprot.org/uniprot/G8LSP0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05300 ^@ http://purl.uniprot.org/uniprot/G8LY32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS05615 ^@ http://purl.uniprot.org/uniprot/G8LY91 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS00215 ^@ http://purl.uniprot.org/uniprot/G8LZD9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/720554:CLOCL_RS09470 ^@ http://purl.uniprot.org/uniprot/G8LVF5 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/720554:CLOCL_RS17435 ^@ http://purl.uniprot.org/uniprot/G8LZ70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS00335 ^@ http://purl.uniprot.org/uniprot/G8LZG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/720554:CLOCL_RS06800 ^@ http://purl.uniprot.org/uniprot/G8M0J0 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/720554:CLOCL_RS12020 ^@ http://purl.uniprot.org/uniprot/G8LZV1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS00030 ^@ http://purl.uniprot.org/uniprot/G8LYP8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/720554:CLOCL_RS04875 ^@ http://purl.uniprot.org/uniprot/G8LX29 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/720554:CLOCL_RS16430 ^@ http://purl.uniprot.org/uniprot/G8LXE0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS11990 ^@ http://purl.uniprot.org/uniprot/G8LZU5 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS11195 ^@ http://purl.uniprot.org/uniprot/G8LYB9 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/720554:CLOCL_RS18945 ^@ http://purl.uniprot.org/uniprot/G8M2F5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS09765 ^@ http://purl.uniprot.org/uniprot/G8LVZ9 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/720554:CLOCL_RS11940 ^@ http://purl.uniprot.org/uniprot/G8LZT5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/720554:CLOCL_RS05490 ^@ http://purl.uniprot.org/uniprot/G8LY70 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/720554:CLOCL_RS20675 ^@ http://purl.uniprot.org/uniprot/G8LUK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/720554:CLOCL_RS07125 ^@ http://purl.uniprot.org/uniprot/G8M1C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03095 ^@ http://purl.uniprot.org/uniprot/G8LUK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03680 ^@ http://purl.uniprot.org/uniprot/G8LVA7 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/720554:CLOCL_RS08880 ^@ http://purl.uniprot.org/uniprot/G8LU41 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/720554:CLOCL_RS10625 ^@ http://purl.uniprot.org/uniprot/G8LX86 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS01930 ^@ http://purl.uniprot.org/uniprot/G8M2Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS14665 ^@ http://purl.uniprot.org/uniprot/G8LUA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SspH family.|||Spore core http://togogenome.org/gene/720554:CLOCL_RS01540 ^@ http://purl.uniprot.org/uniprot/G8M1X4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/720554:CLOCL_RS18960 ^@ http://purl.uniprot.org/uniprot/G8M2F8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/720554:CLOCL_RS09930 ^@ http://purl.uniprot.org/uniprot/G8LW31 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS14800 ^@ http://purl.uniprot.org/uniprot/G8LUC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/720554:CLOCL_RS10905 ^@ http://purl.uniprot.org/uniprot/G8LXT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/720554:CLOCL_RS09580 ^@ http://purl.uniprot.org/uniprot/G8LVH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS12495 ^@ http://purl.uniprot.org/uniprot/G8M0P8 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS16410 ^@ http://purl.uniprot.org/uniprot/G8LXD5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/720554:CLOCL_RS19590 ^@ http://purl.uniprot.org/uniprot/G8LST1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14570 ^@ http://purl.uniprot.org/uniprot/G8LU84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17715 ^@ http://purl.uniprot.org/uniprot/G8LZC3 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/720554:CLOCL_RS19205 ^@ http://purl.uniprot.org/uniprot/G8M2K0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/720554:CLOCL_RS19865 ^@ http://purl.uniprot.org/uniprot/G8LSY6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS12835 ^@ http://purl.uniprot.org/uniprot/G8M1H7 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/720554:CLOCL_RS06540 ^@ http://purl.uniprot.org/uniprot/G8M0D9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/720554:CLOCL_RS17315 ^@ http://purl.uniprot.org/uniprot/G8LYM2 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS08710 ^@ http://purl.uniprot.org/uniprot/G8LU07 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS03215 ^@ http://purl.uniprot.org/uniprot/G8LUM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS07120 ^@ http://purl.uniprot.org/uniprot/G8M1C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS06805 ^@ http://purl.uniprot.org/uniprot/G8M0J1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/720554:CLOCL_RS09925 ^@ http://purl.uniprot.org/uniprot/G8LW30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/720554:CLOCL_RS09655 ^@ http://purl.uniprot.org/uniprot/G8LVJ2 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/720554:CLOCL_RS18985 ^@ http://purl.uniprot.org/uniprot/G8M2G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/720554:CLOCL_RS10525 ^@ http://purl.uniprot.org/uniprot/G8LX66 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/720554:CLOCL_RS20010 ^@ http://purl.uniprot.org/uniprot/G8LTL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS20025 ^@ http://purl.uniprot.org/uniprot/G8LTL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/720554:CLOCL_RS19880 ^@ http://purl.uniprot.org/uniprot/G8LSY9 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/720554:CLOCL_RS00405 ^@ http://purl.uniprot.org/uniprot/G8LZH6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/720554:CLOCL_RS09885 ^@ http://purl.uniprot.org/uniprot/G8LW22 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/720554:CLOCL_RS02975 ^@ http://purl.uniprot.org/uniprot/G8LTX5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS16105 ^@ http://purl.uniprot.org/uniprot/G8LWT3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/720554:CLOCL_RS05065 ^@ http://purl.uniprot.org/uniprot/G8LXK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS15970 ^@ http://purl.uniprot.org/uniprot/G8LWR6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/720554:CLOCL_RS18520 ^@ http://purl.uniprot.org/uniprot/G8M1L1 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/720554:CLOCL_RS04200 ^@ http://purl.uniprot.org/uniprot/G8LVY7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS00180 ^@ http://purl.uniprot.org/uniprot/G8LYS7 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/720554:CLOCL_RS01455 ^@ http://purl.uniprot.org/uniprot/G8M1V7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/720554:CLOCL_RS12860 ^@ http://purl.uniprot.org/uniprot/G8M1I2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/720554:CLOCL_RS08585 ^@ http://purl.uniprot.org/uniprot/G8LTC3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/720554:CLOCL_RS02095 ^@ http://purl.uniprot.org/uniprot/G8LS99 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/720554:CLOCL_RS04655 ^@ http://purl.uniprot.org/uniprot/G8LWY5 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS06605 ^@ http://purl.uniprot.org/uniprot/G8M0F2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/720554:CLOCL_RS01300 ^@ http://purl.uniprot.org/uniprot/G8M168 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/720554:CLOCL_RS12580 ^@ http://purl.uniprot.org/uniprot/G8M0R5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/720554:CLOCL_RS02445 ^@ http://purl.uniprot.org/uniprot/G8LT21 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/720554:CLOCL_RS20610 ^@ http://purl.uniprot.org/uniprot/G8LUJ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS11690 ^@ http://purl.uniprot.org/uniprot/G8LZ36 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/720554:CLOCL_RS04770 ^@ http://purl.uniprot.org/uniprot/G8LX08 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/720554:CLOCL_RS11985 ^@ http://purl.uniprot.org/uniprot/G8LZU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16275 ^@ http://purl.uniprot.org/uniprot/G8LWW3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/720554:CLOCL_RS08820 ^@ http://purl.uniprot.org/uniprot/G8LU29 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/720554:CLOCL_RS01670 ^@ http://purl.uniprot.org/uniprot/G8M2K7 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS15335 ^@ http://purl.uniprot.org/uniprot/G8LVM0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/720554:CLOCL_RS19115 ^@ http://purl.uniprot.org/uniprot/G8M2I2 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/720554:CLOCL_RS18935 ^@ http://purl.uniprot.org/uniprot/G8M2F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/720554:CLOCL_RS19460 ^@ http://purl.uniprot.org/uniprot/G8M397 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/720554:CLOCL_RS14620 ^@ http://purl.uniprot.org/uniprot/G8LU94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/720554:CLOCL_RS06070 ^@ http://purl.uniprot.org/uniprot/G8LZ00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00315 ^@ http://purl.uniprot.org/uniprot/G8LZF8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/720554:CLOCL_RS19610 ^@ http://purl.uniprot.org/uniprot/G8LST5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 53 family. http://togogenome.org/gene/720554:CLOCL_RS04965 ^@ http://purl.uniprot.org/uniprot/G8LXI8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/720554:CLOCL_RS12790 ^@ http://purl.uniprot.org/uniprot/G8M1G8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/720554:CLOCL_RS10650 ^@ http://purl.uniprot.org/uniprot/G8LX91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS03855 ^@ http://purl.uniprot.org/uniprot/G8LVT2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/720554:CLOCL_RS10970 ^@ http://purl.uniprot.org/uniprot/G8LXU4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS04960 ^@ http://purl.uniprot.org/uniprot/G8LXI7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/720554:CLOCL_RS16565 ^@ http://purl.uniprot.org/uniprot/G8LXG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddA subfamily.|||Heterodimer of AddA and AddB/RexB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities. http://togogenome.org/gene/720554:CLOCL_RS16005 ^@ http://purl.uniprot.org/uniprot/G8LWR8 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/720554:CLOCL_RS17565 ^@ http://purl.uniprot.org/uniprot/G8LZ95 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS01610 ^@ http://purl.uniprot.org/uniprot/G8M1Y8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/720554:CLOCL_RS04780 ^@ http://purl.uniprot.org/uniprot/G8LX10 ^@ Caution|||Similarity ^@ Belongs to the acylphosphatase family.|||Belongs to the carbamoyltransferase HypF family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS15020 ^@ http://purl.uniprot.org/uniprot/G8LV19 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/720554:CLOCL_RS20195 ^@ http://purl.uniprot.org/uniprot/G8LTQ1 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/720554:CLOCL_RS00020 ^@ http://purl.uniprot.org/uniprot/G8LYP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/720554:CLOCL_RS15865 ^@ http://purl.uniprot.org/uniprot/G8LWA8 ^@ Similarity ^@ Belongs to the helicase family. RAD3/XPD subfamily. http://togogenome.org/gene/720554:CLOCL_RS13210 ^@ http://purl.uniprot.org/uniprot/G8M299 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS10705 ^@ http://purl.uniprot.org/uniprot/G8LXA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/720554:CLOCL_RS12920 ^@ http://purl.uniprot.org/uniprot/G8M1J4 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/720554:CLOCL_RS02840 ^@ http://purl.uniprot.org/uniprot/G8LTU8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/720554:CLOCL_RS12375 ^@ http://purl.uniprot.org/uniprot/G8M0M4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.|||Belongs to the peptidase A25 family.|||Homotetramer.|||Initiates the rapid degradation of small, acid-soluble proteins during spore germination. http://togogenome.org/gene/720554:CLOCL_RS04785 ^@ http://purl.uniprot.org/uniprot/G8LX11 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/720554:CLOCL_RS20050 ^@ http://purl.uniprot.org/uniprot/G8LTM4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/720554:CLOCL_RS08485 ^@ http://purl.uniprot.org/uniprot/G8LTA3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS18750 ^@ http://purl.uniprot.org/uniprot/G8M1Q8 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/720554:CLOCL_RS04400 ^@ http://purl.uniprot.org/uniprot/G8LWG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS08150 ^@ http://purl.uniprot.org/uniprot/G8LSI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/720554:CLOCL_RS09920 ^@ http://purl.uniprot.org/uniprot/G8LW29 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/720554:CLOCL_RS19170 ^@ http://purl.uniprot.org/uniprot/G8M2J3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/720554:CLOCL_RS10535 ^@ http://purl.uniprot.org/uniprot/G8LX68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/720554:CLOCL_RS07200 ^@ http://purl.uniprot.org/uniprot/G8M1Z9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/720554:CLOCL_RS05975 ^@ http://purl.uniprot.org/uniprot/G8LYY3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/720554:CLOCL_RS13565 ^@ http://purl.uniprot.org/uniprot/G8M316 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/720554:CLOCL_RS01825 ^@ http://purl.uniprot.org/uniprot/G8M2N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/720554:CLOCL_RS00055 ^@ http://purl.uniprot.org/uniprot/G8LYQ3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS18305 ^@ http://purl.uniprot.org/uniprot/G8M0U8 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/720554:CLOCL_RS14735 ^@ http://purl.uniprot.org/uniprot/G8LUB5 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/720554:CLOCL_RS10045 ^@ http://purl.uniprot.org/uniprot/G8LW55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/720554:CLOCL_RS10120 ^@ http://purl.uniprot.org/uniprot/G8LWK6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08225 ^@ http://purl.uniprot.org/uniprot/G8LSJ6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/720554:CLOCL_RS19390 ^@ http://purl.uniprot.org/uniprot/G8M385 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS20210 ^@ http://purl.uniprot.org/uniprot/G8LTQ4 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/720554:CLOCL_RS13470 ^@ http://purl.uniprot.org/uniprot/G8M2Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05105 ^@ http://purl.uniprot.org/uniprot/G8LXL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS11005 ^@ http://purl.uniprot.org/uniprot/G8LXV1 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/720554:CLOCL_RS01060 ^@ http://purl.uniprot.org/uniprot/G8M122 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20600 ^@ http://purl.uniprot.org/uniprot/G8LUJ1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/720554:CLOCL_RS07680 ^@ http://purl.uniprot.org/uniprot/G8M2T9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 9 (cellulase E) family. http://togogenome.org/gene/720554:CLOCL_RS09600 ^@ http://purl.uniprot.org/uniprot/G8LVI1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/720554:CLOCL_RS03160 ^@ http://purl.uniprot.org/uniprot/G8LUL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/720554:CLOCL_RS02650 ^@ http://purl.uniprot.org/uniprot/G8LT57 ^@ Activity Regulation|||Function|||Similarity ^@ Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.|||Belongs to the ATP:guanido phosphotransferase family.|||Catalyzes the specific phosphorylation of arginine residues in proteins. http://togogenome.org/gene/720554:CLOCL_RS11780 ^@ http://purl.uniprot.org/uniprot/G8LZ51 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS08950 ^@ http://purl.uniprot.org/uniprot/G8LU55 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/720554:CLOCL_RS16375 ^@ http://purl.uniprot.org/uniprot/G8LXC7 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS20215 ^@ http://purl.uniprot.org/uniprot/G8LTQ5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/720554:CLOCL_RS15190 ^@ http://purl.uniprot.org/uniprot/G8LV50 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/720554:CLOCL_RS17280 ^@ http://purl.uniprot.org/uniprot/G8LYL6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/720554:CLOCL_RS00515 ^@ http://purl.uniprot.org/uniprot/G8LZJ7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/720554:CLOCL_RS06645 ^@ http://purl.uniprot.org/uniprot/G8M0G0 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS15810 ^@ http://purl.uniprot.org/uniprot/G8LW98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS06285 ^@ http://purl.uniprot.org/uniprot/G8LZN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00080 ^@ http://purl.uniprot.org/uniprot/G8LYQ6 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/720554:CLOCL_RS09980 ^@ http://purl.uniprot.org/uniprot/G8LW43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS01080 ^@ http://purl.uniprot.org/uniprot/G8M126 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS08640 ^@ http://purl.uniprot.org/uniprot/G8LTD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/720554:CLOCL_RS07580 ^@ http://purl.uniprot.org/uniprot/G8M2S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20260 ^@ http://purl.uniprot.org/uniprot/G8LTR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/720554:CLOCL_RS12845 ^@ http://purl.uniprot.org/uniprot/G8M1H9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS02405 ^@ http://purl.uniprot.org/uniprot/G8LT13 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/720554:CLOCL_RS06530 ^@ http://purl.uniprot.org/uniprot/G8M0D7 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/720554:CLOCL_RS10135 ^@ http://purl.uniprot.org/uniprot/G8LWK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS14130 ^@ http://purl.uniprot.org/uniprot/G8LTD9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS06385 ^@ http://purl.uniprot.org/uniprot/G8LZQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/720554:CLOCL_RS10810 ^@ http://purl.uniprot.org/uniprot/G8LXR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/720554:CLOCL_RS14780 ^@ http://purl.uniprot.org/uniprot/G8LUC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12100 ^@ http://purl.uniprot.org/uniprot/G8LZW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00915 ^@ http://purl.uniprot.org/uniprot/G8M0Z5 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/720554:CLOCL_RS08955 ^@ http://purl.uniprot.org/uniprot/G8LU56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS10690 ^@ http://purl.uniprot.org/uniprot/G8LX98 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS00910 ^@ http://purl.uniprot.org/uniprot/G8M0C8 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/720554:CLOCL_RS05545 ^@ http://purl.uniprot.org/uniprot/G8LY79 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/720554:CLOCL_RS12930 ^@ http://purl.uniprot.org/uniprot/G8M1J6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/720554:CLOCL_RS04215 ^@ http://purl.uniprot.org/uniprot/G8LWD1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/720554:CLOCL_RS11150 ^@ http://purl.uniprot.org/uniprot/G8LYB0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/720554:CLOCL_RS12990 ^@ http://purl.uniprot.org/uniprot/G8M1K8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/720554:CLOCL_RS17610 ^@ http://purl.uniprot.org/uniprot/G8LZA4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS09960 ^@ http://purl.uniprot.org/uniprot/G8LW38 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12415 ^@ http://purl.uniprot.org/uniprot/G8M0N2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/720554:CLOCL_RS12660 ^@ http://purl.uniprot.org/uniprot/G8M1E6 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/720554:CLOCL_RS04835 ^@ http://purl.uniprot.org/uniprot/G8LX21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/720554:CLOCL_RS14115 ^@ http://purl.uniprot.org/uniprot/G8LSS9 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/720554:CLOCL_RS07720 ^@ http://purl.uniprot.org/uniprot/G8M2U7 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/720554:CLOCL_RS13815 ^@ http://purl.uniprot.org/uniprot/G8LSM0 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS15025 ^@ http://purl.uniprot.org/uniprot/G8LV20 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS16215 ^@ http://purl.uniprot.org/uniprot/G8LWV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS18250 ^@ http://purl.uniprot.org/uniprot/G8M0T7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS20655 ^@ http://purl.uniprot.org/uniprot/G8LUJ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/720554:CLOCL_RS18430 ^@ http://purl.uniprot.org/uniprot/G8M0X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS04760 ^@ http://purl.uniprot.org/uniprot/G8LX06 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/720554:CLOCL_RS17400 ^@ http://purl.uniprot.org/uniprot/G8LYN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS12010 ^@ http://purl.uniprot.org/uniprot/G8LZU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/720554:CLOCL_RS01560 ^@ http://purl.uniprot.org/uniprot/G8M1X8 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS15205 ^@ http://purl.uniprot.org/uniprot/G8LV53 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family. http://togogenome.org/gene/720554:CLOCL_RS11660 ^@ http://purl.uniprot.org/uniprot/G8LZ28 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/720554:CLOCL_RS05420 ^@ http://purl.uniprot.org/uniprot/G8LY56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/720554:CLOCL_RS12830 ^@ http://purl.uniprot.org/uniprot/G8M1H6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS18900 ^@ http://purl.uniprot.org/uniprot/G8M2E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/720554:CLOCL_RS05640 ^@ http://purl.uniprot.org/uniprot/G8LY96 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS14945 ^@ http://purl.uniprot.org/uniprot/G8LV07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/720554:CLOCL_RS00520 ^@ http://purl.uniprot.org/uniprot/G8LZJ8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/720554:CLOCL_RS11125 ^@ http://purl.uniprot.org/uniprot/G8LYA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/720554:CLOCL_RS08795 ^@ http://purl.uniprot.org/uniprot/G8LU24 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/720554:CLOCL_RS01770 ^@ http://purl.uniprot.org/uniprot/G8M2M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06975 ^@ http://purl.uniprot.org/uniprot/G8M196 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/720554:CLOCL_RS19190 ^@ http://purl.uniprot.org/uniprot/G8M2J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS13520 ^@ http://purl.uniprot.org/uniprot/G8M307 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/720554:CLOCL_RS10345 ^@ http://purl.uniprot.org/uniprot/G8LWQ0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/720554:CLOCL_RS03465 ^@ http://purl.uniprot.org/uniprot/G8LWJ3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS05090 ^@ http://purl.uniprot.org/uniprot/G8LXL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS17755 ^@ http://purl.uniprot.org/uniprot/G8LZC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/720554:CLOCL_RS20125 ^@ http://purl.uniprot.org/uniprot/G8LTP0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS11055 ^@ http://purl.uniprot.org/uniprot/G8LXV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS04680 ^@ http://purl.uniprot.org/uniprot/G8LWZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/720554:CLOCL_RS10390 ^@ http://purl.uniprot.org/uniprot/G8LWR0 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/720554:CLOCL_RS02655 ^@ http://purl.uniprot.org/uniprot/G8LT58 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/720554:CLOCL_RS00785 ^@ http://purl.uniprot.org/uniprot/G8M0A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS12025 ^@ http://purl.uniprot.org/uniprot/G8LZV2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/720554:CLOCL_RS03990 ^@ http://purl.uniprot.org/uniprot/G8LWJ3 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS02590 ^@ http://purl.uniprot.org/uniprot/G8LT46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/720554:CLOCL_RS10385 ^@ http://purl.uniprot.org/uniprot/G8LWQ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/720554:CLOCL_RS05910 ^@ http://purl.uniprot.org/uniprot/G8LYX0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/720554:CLOCL_RS17840 ^@ http://purl.uniprot.org/uniprot/G8LZZ9 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS06050 ^@ http://purl.uniprot.org/uniprot/G8LYZ6 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/720554:CLOCL_RS04690 ^@ http://purl.uniprot.org/uniprot/G8LWZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/720554:CLOCL_RS01450 ^@ http://purl.uniprot.org/uniprot/G8M1V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/720554:CLOCL_RS08590 ^@ http://purl.uniprot.org/uniprot/G8LTC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/720554:CLOCL_RS05455 ^@ http://purl.uniprot.org/uniprot/G8LY63 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS12870 ^@ http://purl.uniprot.org/uniprot/G8M1I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10115 ^@ http://purl.uniprot.org/uniprot/G8LWK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05405 ^@ http://purl.uniprot.org/uniprot/G8LY53 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/720554:CLOCL_RS12040 ^@ http://purl.uniprot.org/uniprot/G8LZV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS06900 ^@ http://purl.uniprot.org/uniprot/G8M179 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS10945 ^@ http://purl.uniprot.org/uniprot/G8LXT9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/720554:CLOCL_RS17545 ^@ http://purl.uniprot.org/uniprot/G8LZ91 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08995 ^@ http://purl.uniprot.org/uniprot/G8LU65 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/720554:CLOCL_RS20390 ^@ http://purl.uniprot.org/uniprot/G8LUF2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS09185 ^@ http://purl.uniprot.org/uniprot/G8LUW0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS19540 ^@ http://purl.uniprot.org/uniprot/G8M3B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS09015 ^@ http://purl.uniprot.org/uniprot/G8LU69 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS03790 ^@ http://purl.uniprot.org/uniprot/G8LVD1 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/720554:CLOCL_RS06655 ^@ http://purl.uniprot.org/uniprot/G8M0G2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS12265 ^@ http://purl.uniprot.org/uniprot/G8M0K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06230 ^@ http://purl.uniprot.org/uniprot/G8M2Y2 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS08515 ^@ http://purl.uniprot.org/uniprot/G8LTA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/720554:CLOCL_RS19855 ^@ http://purl.uniprot.org/uniprot/G8LSY4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS01405 ^@ http://purl.uniprot.org/uniprot/G8M1U7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/720554:CLOCL_RS09265 ^@ http://purl.uniprot.org/uniprot/G8LUX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00735 ^@ http://purl.uniprot.org/uniprot/G8M096 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS00305 ^@ http://purl.uniprot.org/uniprot/G8LZF6 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/720554:CLOCL_RS18090 ^@ http://purl.uniprot.org/uniprot/G8M042 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/720554:CLOCL_RS18670 ^@ http://purl.uniprot.org/uniprot/G8M1P3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/720554:CLOCL_RS12355 ^@ http://purl.uniprot.org/uniprot/G8M0M0 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/720554:CLOCL_RS04810 ^@ http://purl.uniprot.org/uniprot/G8LX16 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/720554:CLOCL_RS04535 ^@ http://purl.uniprot.org/uniprot/G8LWI7 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/720554:CLOCL_RS08915 ^@ http://purl.uniprot.org/uniprot/G8LU48 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/720554:CLOCL_RS08575 ^@ http://purl.uniprot.org/uniprot/G8LTC1 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/720554:CLOCL_RS08350 ^@ http://purl.uniprot.org/uniprot/G8LT76 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS05130 ^@ http://purl.uniprot.org/uniprot/G8LXM0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/720554:CLOCL_RS10715 ^@ http://purl.uniprot.org/uniprot/G8LXA3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/720554:CLOCL_RS12080 ^@ http://purl.uniprot.org/uniprot/G8LZW3 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/720554:CLOCL_RS05875 ^@ http://purl.uniprot.org/uniprot/G8LYW3 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/720554:CLOCL_RS18675 ^@ http://purl.uniprot.org/uniprot/G8M1P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS07245 ^@ http://purl.uniprot.org/uniprot/G8M207 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10675 ^@ http://purl.uniprot.org/uniprot/G8LX95 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/720554:CLOCL_RS16285 ^@ http://purl.uniprot.org/uniprot/G8LWW5 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/720554:CLOCL_RS13635 ^@ http://purl.uniprot.org/uniprot/G8M330 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/720554:CLOCL_RS18975 ^@ http://purl.uniprot.org/uniprot/G8M2G1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/720554:CLOCL_RS10530 ^@ http://purl.uniprot.org/uniprot/G8LX67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/720554:CLOCL_RS10360 ^@ http://purl.uniprot.org/uniprot/G8LWQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/720554:CLOCL_RS02620 ^@ http://purl.uniprot.org/uniprot/G8LT50 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/720554:CLOCL_RS18885 ^@ http://purl.uniprot.org/uniprot/G8M2E3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/720554:CLOCL_RS01400 ^@ http://purl.uniprot.org/uniprot/G8M1U6 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/720554:CLOCL_RS10815 ^@ http://purl.uniprot.org/uniprot/G8LXR2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/720554:CLOCL_RS10855 ^@ http://purl.uniprot.org/uniprot/G8LXS1 ^@ Similarity|||Subunit ^@ Belongs to the MtrB family.|||Oligomer of 11 identical subunits arranged in doughnut-like structure. http://togogenome.org/gene/720554:CLOCL_RS01385 ^@ http://purl.uniprot.org/uniprot/G8M1U3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/720554:CLOCL_RS08925 ^@ http://purl.uniprot.org/uniprot/G8LU50 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/720554:CLOCL_RS00010 ^@ http://purl.uniprot.org/uniprot/G8LYP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/720554:CLOCL_RS05820 ^@ http://purl.uniprot.org/uniprot/G8LYV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11815 ^@ http://purl.uniprot.org/uniprot/G8LZ58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/720554:CLOCL_RS16280 ^@ http://purl.uniprot.org/uniprot/G8LWW4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS06190 ^@ http://purl.uniprot.org/uniprot/G8LZM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/720554:CLOCL_RS05870 ^@ http://purl.uniprot.org/uniprot/G8LYW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS02500 ^@ http://purl.uniprot.org/uniprot/G8LT28 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/720554:CLOCL_RS14135 ^@ http://purl.uniprot.org/uniprot/G8LTE0 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/720554:CLOCL_RS04235 ^@ http://purl.uniprot.org/uniprot/G8LWD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05190 ^@ http://purl.uniprot.org/uniprot/G8LXN0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/720554:CLOCL_RS15045 ^@ http://purl.uniprot.org/uniprot/G8LV24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03255 ^@ http://purl.uniprot.org/uniprot/G8LUN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/720554:CLOCL_RS00040 ^@ http://purl.uniprot.org/uniprot/G8LYQ0 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/720554:CLOCL_RS07265 ^@ http://purl.uniprot.org/uniprot/G8M210 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/720554:CLOCL_RS12665 ^@ http://purl.uniprot.org/uniprot/G8M1E7 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/720554:CLOCL_RS14555 ^@ http://purl.uniprot.org/uniprot/G8LU80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS01410 ^@ http://purl.uniprot.org/uniprot/G8M1U8 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/720554:CLOCL_RS07145 ^@ http://purl.uniprot.org/uniprot/G8M1D1 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/720554:CLOCL_RS16680 ^@ http://purl.uniprot.org/uniprot/G8LXX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS04675 ^@ http://purl.uniprot.org/uniprot/G8LWY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS20650 ^@ http://purl.uniprot.org/uniprot/G8LUJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/720554:CLOCL_RS10350 ^@ http://purl.uniprot.org/uniprot/G8LWQ1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/720554:CLOCL_RS16755 ^@ http://purl.uniprot.org/uniprot/G8LXY7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/720554:CLOCL_RS12395 ^@ http://purl.uniprot.org/uniprot/G8M0M8 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/720554:CLOCL_RS11185 ^@ http://purl.uniprot.org/uniprot/G8LYB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16035 ^@ http://purl.uniprot.org/uniprot/G8LWS4 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/720554:CLOCL_RS09805 ^@ http://purl.uniprot.org/uniprot/G8LW08 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS16270 ^@ http://purl.uniprot.org/uniprot/G8LWW2 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/720554:CLOCL_RS08400 ^@ http://purl.uniprot.org/uniprot/G8LT86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS06835 ^@ http://purl.uniprot.org/uniprot/G8M0J7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/720554:CLOCL_RS14220 ^@ http://purl.uniprot.org/uniprot/G8LTF7 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/720554:CLOCL_RS05440 ^@ http://purl.uniprot.org/uniprot/G8LY60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/720554:CLOCL_RS20680 ^@ http://purl.uniprot.org/uniprot/G8LV62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/720554:CLOCL_RS02040 ^@ http://purl.uniprot.org/uniprot/G8LS89 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/720554:CLOCL_RS19630 ^@ http://purl.uniprot.org/uniprot/G8LST9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/720554:CLOCL_RS04740 ^@ http://purl.uniprot.org/uniprot/G8LX02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS18640 ^@ http://purl.uniprot.org/uniprot/G8M1N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06665 ^@ http://purl.uniprot.org/uniprot/G8M0G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/720554:CLOCL_RS13380 ^@ http://purl.uniprot.org/uniprot/G8M2D1 ^@ Similarity ^@ Belongs to the tRNA(His) guanylyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS19030 ^@ http://purl.uniprot.org/uniprot/G8M2H2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/720554:CLOCL_RS10885 ^@ http://purl.uniprot.org/uniprot/G8LXS7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS09555 ^@ http://purl.uniprot.org/uniprot/G8LVH2 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/720554:CLOCL_RS14695 ^@ http://purl.uniprot.org/uniprot/G8LUA9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/720554:CLOCL_RS17305 ^@ http://purl.uniprot.org/uniprot/G8LYM0 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/720554:CLOCL_RS09535 ^@ http://purl.uniprot.org/uniprot/G8LVG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS16130 ^@ http://purl.uniprot.org/uniprot/G8LWT8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/720554:CLOCL_RS11810 ^@ http://purl.uniprot.org/uniprot/G8LZ57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS16260 ^@ http://purl.uniprot.org/uniprot/G8LWW0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS06470 ^@ http://purl.uniprot.org/uniprot/G8LZS0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/720554:CLOCL_RS06635 ^@ http://purl.uniprot.org/uniprot/G8M0F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS17710 ^@ http://purl.uniprot.org/uniprot/G8LZC2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS11190 ^@ http://purl.uniprot.org/uniprot/G8LYB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS11905 ^@ http://purl.uniprot.org/uniprot/G8LZS7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/720554:CLOCL_RS11635 ^@ http://purl.uniprot.org/uniprot/G8LZ23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/720554:CLOCL_RS10610 ^@ http://purl.uniprot.org/uniprot/G8LX83 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/720554:CLOCL_RS03320 ^@ http://purl.uniprot.org/uniprot/G8LUP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/720554:CLOCL_RS16050 ^@ http://purl.uniprot.org/uniprot/G8LWS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/720554:CLOCL_RS11665 ^@ http://purl.uniprot.org/uniprot/G8LZ30 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/720554:CLOCL_RS00540 ^@ http://purl.uniprot.org/uniprot/G8M058 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS14195 ^@ http://purl.uniprot.org/uniprot/G8LTF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS15035 ^@ http://purl.uniprot.org/uniprot/G8LV22 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/720554:CLOCL_RS17780 ^@ http://purl.uniprot.org/uniprot/G8LZD4 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/720554:CLOCL_RS08705 ^@ http://purl.uniprot.org/uniprot/G8LU06 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/720554:CLOCL_RS04380 ^@ http://purl.uniprot.org/uniprot/G8LWF6 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/720554:CLOCL_RS13620 ^@ http://purl.uniprot.org/uniprot/G8M327 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS06555 ^@ http://purl.uniprot.org/uniprot/G8M0E2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS06175 ^@ http://purl.uniprot.org/uniprot/G8LZL7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/720554:CLOCL_RS11240 ^@ http://purl.uniprot.org/uniprot/G8LYC8 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/720554:CLOCL_RS10000 ^@ http://purl.uniprot.org/uniprot/G8LW47 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS16010 ^@ http://purl.uniprot.org/uniprot/G8LWR9 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/720554:CLOCL_RS03575 ^@ http://purl.uniprot.org/uniprot/G8LV85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ro 60 kDa family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS07005 ^@ http://purl.uniprot.org/uniprot/G8M1A2 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/720554:CLOCL_RS10790 ^@ http://purl.uniprot.org/uniprot/G8LXQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS03300 ^@ http://purl.uniprot.org/uniprot/G8LUP4 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/720554:CLOCL_RS07175 ^@ http://purl.uniprot.org/uniprot/G8M1D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS17115 ^@ http://purl.uniprot.org/uniprot/G8LYI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS10020 ^@ http://purl.uniprot.org/uniprot/G8LW50 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/720554:CLOCL_RS14775 ^@ http://purl.uniprot.org/uniprot/G8LUC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS08580 ^@ http://purl.uniprot.org/uniprot/G8LTC2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/720554:CLOCL_RS00590 ^@ http://purl.uniprot.org/uniprot/G8M068 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/720554:CLOCL_RS10485 ^@ http://purl.uniprot.org/uniprot/G8LX58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS06465 ^@ http://purl.uniprot.org/uniprot/G8LZR9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/720554:CLOCL_RS12285 ^@ http://purl.uniprot.org/uniprot/G8M0K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS14035 ^@ http://purl.uniprot.org/uniprot/G8LSR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS00545 ^@ http://purl.uniprot.org/uniprot/G8M059 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS14385 ^@ http://purl.uniprot.org/uniprot/G8LTJ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS19745 ^@ http://purl.uniprot.org/uniprot/G8LSW2 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/720554:CLOCL_RS19700 ^@ http://purl.uniprot.org/uniprot/G8LSV3 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/720554:CLOCL_RS21050 ^@ http://purl.uniprot.org/uniprot/G8LUW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/720554:CLOCL_RS19215 ^@ http://purl.uniprot.org/uniprot/G8M2K2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/720554:CLOCL_RS08415 ^@ http://purl.uniprot.org/uniprot/G8LT89 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/720554:CLOCL_RS02410 ^@ http://purl.uniprot.org/uniprot/G8LT14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/720554:CLOCL_RS05380 ^@ http://purl.uniprot.org/uniprot/G8LY48 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/720554:CLOCL_RS12535 ^@ http://purl.uniprot.org/uniprot/G8M0Q6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/720554:CLOCL_RS09945 ^@ http://purl.uniprot.org/uniprot/G8LW34 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/720554:CLOCL_RS12410 ^@ http://purl.uniprot.org/uniprot/G8M0N1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/720554:CLOCL_RS18205 ^@ http://purl.uniprot.org/uniprot/G8M0S8 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/720554:CLOCL_RS10835 ^@ http://purl.uniprot.org/uniprot/G8LXR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/720554:CLOCL_RS12345 ^@ http://purl.uniprot.org/uniprot/G8M0L8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/720554:CLOCL_RS09780 ^@ http://purl.uniprot.org/uniprot/G8LW02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/720554:CLOCL_RS20095 ^@ http://purl.uniprot.org/uniprot/G8LTN3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/720554:CLOCL_RS07180 ^@ http://purl.uniprot.org/uniprot/G8M1D7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/720554:CLOCL_RS03830 ^@ http://purl.uniprot.org/uniprot/G8LVS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/720554:CLOCL_RS08345 ^@ http://purl.uniprot.org/uniprot/G8LT75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/720554:CLOCL_RS05375 ^@ http://purl.uniprot.org/uniprot/G8LY47 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/720554:CLOCL_RS19810 ^@ http://purl.uniprot.org/uniprot/G8LSX5 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/720554:CLOCL_RS08935 ^@ http://purl.uniprot.org/uniprot/G8LU52 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/720554:CLOCL_RS15765 ^@ http://purl.uniprot.org/uniprot/G8LW89 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/720554:CLOCL_RS07205 ^@ http://purl.uniprot.org/uniprot/G8M200 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/720554:CLOCL_RS17635 ^@ http://purl.uniprot.org/uniprot/G8LZA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/720554:CLOCL_RS02200 ^@ http://purl.uniprot.org/uniprot/G8LSB6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/720554:CLOCL_RS09800 ^@ http://purl.uniprot.org/uniprot/G8LW07 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS09405 ^@ http://purl.uniprot.org/uniprot/G8LVE2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/720554:CLOCL_RS05980 ^@ http://purl.uniprot.org/uniprot/G8LYY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/720554:CLOCL_RS04775 ^@ http://purl.uniprot.org/uniprot/G8LX09 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/720554:CLOCL_RS07000 ^@ http://purl.uniprot.org/uniprot/G8M1A1 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/720554:CLOCL_RS06810 ^@ http://purl.uniprot.org/uniprot/G8M0J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/720554:CLOCL_RS00115 ^@ http://purl.uniprot.org/uniprot/G8LYR3 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/720554:CLOCL_RS12380 ^@ http://purl.uniprot.org/uniprot/G8M0M5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/720554:CLOCL_RS05250 ^@ http://purl.uniprot.org/uniprot/G8LXP2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/720554:CLOCL_RS20280 ^@ http://purl.uniprot.org/uniprot/G8LTR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/720554:CLOCL_RS05635 ^@ http://purl.uniprot.org/uniprot/G8LY95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/720554:CLOCL_RS01465 ^@ http://purl.uniprot.org/uniprot/G8M1V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/720554:CLOCL_RS10395 ^@ http://purl.uniprot.org/uniprot/G8LWR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/720554:CLOCL_RS03210 ^@ http://purl.uniprot.org/uniprot/G8LUM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/720554:CLOCL_RS04000 ^@ http://purl.uniprot.org/uniprot/G8LVV3 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/720554:CLOCL_RS09545 ^@ http://purl.uniprot.org/uniprot/G8LVH0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/720554:CLOCL_RS23340 ^@ http://purl.uniprot.org/uniprot/G8LWA7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/720554:CLOCL_RS01535 ^@ http://purl.uniprot.org/uniprot/G8M1X3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.