http://togogenome.org/gene/7962:LOC109072598 ^@ http://purl.uniprot.org/uniprot/A0A8C1ENM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/7962:LOC109097775 ^@ http://purl.uniprot.org/uniprot/A0A8C1XVB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WRB/GET1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109100539 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0T0 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/7962:LOC109097002 ^@ http://purl.uniprot.org/uniprot/A0A8C2A2H9 ^@ Function|||Similarity ^@ Belongs to the MON1/SAND family.|||Plays an important role in membrane trafficking through the secretory apparatus. http://togogenome.org/gene/7962:LOC109066887 ^@ http://purl.uniprot.org/uniprot/A0A8C1NKH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109045714 ^@ http://purl.uniprot.org/uniprot/A0A8C1EWN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRH family.|||Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.|||Secreted http://togogenome.org/gene/7962:LOC109057688 ^@ http://purl.uniprot.org/uniprot/A0A8C1AT43|||http://purl.uniprot.org/uniprot/A0A8C1RP35 ^@ Similarity ^@ Belongs to the CCM2 family. http://togogenome.org/gene/7962:LOC109105619 ^@ http://purl.uniprot.org/uniprot/A0A8C1DT51|||http://purl.uniprot.org/uniprot/A5LG11 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109101507 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFL1|||http://purl.uniprot.org/uniprot/A0A8C1THU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109077324 ^@ http://purl.uniprot.org/uniprot/A0A8C1H343 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UCMA family.|||May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.|||extracellular matrix http://togogenome.org/gene/7962:LOC109098187 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109093850 ^@ http://purl.uniprot.org/uniprot/A0A8C1AA39 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109057206 ^@ http://purl.uniprot.org/uniprot/A0A8C1EK61 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/7962:atp1b3b ^@ http://purl.uniprot.org/uniprot/A0A8C1CNC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/7962:LOC109081666 ^@ http://purl.uniprot.org/uniprot/A0A8C1DPT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109097022 ^@ http://purl.uniprot.org/uniprot/A0A8C1BK76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/7962:tsen15 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKP6 ^@ Similarity ^@ Belongs to the SEN15 family. http://togogenome.org/gene/7962:LOC109080067 ^@ http://purl.uniprot.org/uniprot/A0A8C1DES1 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:tob1b ^@ http://purl.uniprot.org/uniprot/A0A8C1ILW2 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109092900 ^@ http://purl.uniprot.org/uniprot/A0A8C0YR37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109050109 ^@ http://purl.uniprot.org/uniprot/A0A8C1RTD5 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/7962:LOC109096111 ^@ http://purl.uniprot.org/uniprot/A0A8C1EYP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109109143 ^@ http://purl.uniprot.org/uniprot/A0A8C1JSB3 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/7962:LOC109111463 ^@ http://purl.uniprot.org/uniprot/A0A8C0YR03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. http://togogenome.org/gene/7962:LOC109100885 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q230 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lysyl oxidase family.|||Contains 1 lysine tyrosylquinone.|||Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).|||The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.|||extracellular space http://togogenome.org/gene/7962:LOC109082415 ^@ http://purl.uniprot.org/uniprot/A0A8C1KVL9 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ATPase epsilon family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. http://togogenome.org/gene/7962:tmem138 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM138 family.|||Membrane|||Required for ciliogenesis.|||Vacuole membrane|||cilium http://togogenome.org/gene/7962:cnrip1a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2D4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CNRIP family.|||Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.|||Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. http://togogenome.org/gene/7962:ing5a ^@ http://purl.uniprot.org/uniprot/A0A8C1B707 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/7962:LOC109112493 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:mrpl44 ^@ http://purl.uniprot.org/uniprot/A0A8C1E226 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.|||Mitochondrion http://togogenome.org/gene/7962:LOC109079154 ^@ http://purl.uniprot.org/uniprot/A0A8C1M6I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/7962:LOC109103611 ^@ http://purl.uniprot.org/uniprot/A0A8C1VFP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109068611 ^@ http://purl.uniprot.org/uniprot/A0A8C1YXA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIII family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:pomgnt2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BA30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 61 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:cavin1a ^@ http://purl.uniprot.org/uniprot/A0A8C0XU30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAVIN family.|||caveola http://togogenome.org/gene/7962:LOC109086733 ^@ http://purl.uniprot.org/uniprot/A0A8C1FWB8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/7962:LOC109098410 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMU5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Golgi apparatus membrane|||Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.|||Membrane|||The cofactor is mostly bound to the substrate. http://togogenome.org/gene/7962:noto ^@ http://purl.uniprot.org/uniprot/A0A8C1ES38 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109095569 ^@ http://purl.uniprot.org/uniprot/A0A8C2PVZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRH family.|||Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.|||Secreted http://togogenome.org/gene/7962:atp6v0ca ^@ http://purl.uniprot.org/uniprot/A0A8C1DKK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane|||clathrin-coated vesicle membrane|||synaptic vesicle membrane http://togogenome.org/gene/7962:LOC109058581 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/7962:LOC109068392 ^@ http://purl.uniprot.org/uniprot/A0A8C2IPC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109110200 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109110593 ^@ http://purl.uniprot.org/uniprot/A0A8C1C2U6 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/7962:LOC109098668 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC7 family.|||Nucleus|||Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. http://togogenome.org/gene/7962:LOC109090473 ^@ http://purl.uniprot.org/uniprot/A0A8C1TR89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109111521 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:prokr1a ^@ http://purl.uniprot.org/uniprot/A0A8C0XVY7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:slc9a3r1a ^@ http://purl.uniprot.org/uniprot/A0A8C1BJF3 ^@ Function|||Subcellular Location Annotation ^@ Endomembrane system|||Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.|||filopodium|||microvillus|||ruffle http://togogenome.org/gene/7962:rbx1 ^@ http://purl.uniprot.org/uniprot/A0A8C1N2S0 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/7962:LOC109110904 ^@ http://purl.uniprot.org/uniprot/A0A8C1DX09 ^@ Function|||Subcellular Location Annotation ^@ Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.|||Cytoplasm http://togogenome.org/gene/7962:pfdn6 ^@ http://purl.uniprot.org/uniprot/A0A8C1AYH8 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/7962:LOC109109281 ^@ http://purl.uniprot.org/uniprot/A0A8C1CL10 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109084217 ^@ http://purl.uniprot.org/uniprot/A0A8C2HWS7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109080713 ^@ http://purl.uniprot.org/uniprot/A0A8C1DF04 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:shox2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZA0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109054310 ^@ http://purl.uniprot.org/uniprot/A0A8C1UA11 ^@ Similarity ^@ Belongs to the PPDPF family. http://togogenome.org/gene/7962:fshb ^@ http://purl.uniprot.org/uniprot/A0A8C1BC83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7962:LOC122134048 ^@ http://purl.uniprot.org/uniprot/A0A8C1KJJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Cytoplasm http://togogenome.org/gene/7962:zgc:154093 ^@ http://purl.uniprot.org/uniprot/A0A8C1GMZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109049733 ^@ http://purl.uniprot.org/uniprot/A0A8C1BY72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:crybgx ^@ http://purl.uniprot.org/uniprot/A0A8C1JFG2 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109108988 ^@ http://purl.uniprot.org/uniprot/A0A8C1ARP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:gphb5 ^@ http://purl.uniprot.org/uniprot/A0A8C1AD56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7962:LOC109072316 ^@ http://purl.uniprot.org/uniprot/A0A8C1JH59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nup35 family.|||Functions as a component of the nuclear pore complex (NPC).|||nuclear pore complex http://togogenome.org/gene/7962:ptpn6 ^@ http://purl.uniprot.org/uniprot/A0A8C1BTM4|||http://purl.uniprot.org/uniprot/A0A8C1BYT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.|||Cytoplasm http://togogenome.org/gene/7962:LOC109047706 ^@ http://purl.uniprot.org/uniprot/A0A8C1B878 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109100973 ^@ http://purl.uniprot.org/uniprot/A0A8C1A256 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic mitochondrial porin family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:dynll2a ^@ http://purl.uniprot.org/uniprot/A0A8C1Q3X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:asf1bb ^@ http://purl.uniprot.org/uniprot/A0A8C2E0J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109110716 ^@ http://purl.uniprot.org/uniprot/A0A8C0YB91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Secreted http://togogenome.org/gene/7962:LOC109048535 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:ca8h22orf39 ^@ http://purl.uniprot.org/uniprot/A0A8C1E940 ^@ Similarity ^@ Belongs to the UPF0545 family. http://togogenome.org/gene/7962:LOC109109926 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2T3 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/7962:LOC109109984 ^@ http://purl.uniprot.org/uniprot/A0A8C1BMQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DDB2/WDR76 family.|||Nucleus http://togogenome.org/gene/7962:mid1ip1l ^@ http://purl.uniprot.org/uniprot/A0A8C2EC51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:foxo3a ^@ http://purl.uniprot.org/uniprot/A0A8C1E701 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:ptger2b ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4A4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:timm8a ^@ http://purl.uniprot.org/uniprot/A0A8C2DHS8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7962:LOC109104284 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMQ8 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/7962:kcnj19a ^@ http://purl.uniprot.org/uniprot/A0A8C2DYV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.|||Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.|||Membrane|||This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. http://togogenome.org/gene/7962:LOC109102110 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3T6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/7962:bmp2b ^@ http://purl.uniprot.org/uniprot/A0A8C1I1E6 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109069878 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/7962:jagn1a ^@ http://purl.uniprot.org/uniprot/A0A8C1CGL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the jagunal family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109064860 ^@ http://purl.uniprot.org/uniprot/A0A8C1J9L8 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/7962:LOC109089262 ^@ http://purl.uniprot.org/uniprot/A0A8C1FN88|||http://purl.uniprot.org/uniprot/A0A8C1HNE8 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/7962:LOC109066001 ^@ http://purl.uniprot.org/uniprot/A0A8C1DU68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:ddr1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YPR4|||http://purl.uniprot.org/uniprot/A0A8C0YPS3|||http://purl.uniprot.org/uniprot/A0A8C1A6L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109079201 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:gsg1l ^@ http://purl.uniprot.org/uniprot/A0A8C2I5U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSG1 family.|||Membrane http://togogenome.org/gene/7962:LOC109106070 ^@ http://purl.uniprot.org/uniprot/A0A8C1SW71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC42SE/SPEC family.|||Cell membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/7962:LOC109086734 ^@ http://purl.uniprot.org/uniprot/A0A8C1PVF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIb family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109068141 ^@ http://purl.uniprot.org/uniprot/A0A8C1CL36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexin family.|||Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/7962:hoxb10a ^@ http://purl.uniprot.org/uniprot/A0A8C1FJM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109090685 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/7962:LOC109099988 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFP1 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/7962:LOC109105946 ^@ http://purl.uniprot.org/uniprot/A0A8C1L2E0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:LOC122133945 ^@ http://purl.uniprot.org/uniprot/A0A8C1A287 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:pdca ^@ http://purl.uniprot.org/uniprot/A0A8C2D3K9 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/7962:LOC109059470 ^@ http://purl.uniprot.org/uniprot/A0A0C6E5C9 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:phox2bb ^@ http://purl.uniprot.org/uniprot/A0A8C1IFF3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:wnt3 ^@ http://purl.uniprot.org/uniprot/A0A8C1H6K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109103333 ^@ http://purl.uniprot.org/uniprot/A0A8C2FBT3 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:exorh ^@ http://purl.uniprot.org/uniprot/A0A8C1PHI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109088360 ^@ http://purl.uniprot.org/uniprot/A0A8C2HCJ0 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:LOC109103267 ^@ http://purl.uniprot.org/uniprot/A0A8C1D842|||http://purl.uniprot.org/uniprot/A0A8C1DGE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.|||Membrane|||Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons. http://togogenome.org/gene/7962:fgf1b ^@ http://purl.uniprot.org/uniprot/A0A8C1SC95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||Nucleus|||Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.|||Secreted|||cell cortex|||cytosol http://togogenome.org/gene/7962:wdr45 ^@ http://purl.uniprot.org/uniprot/A0A8C2GT61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PROPPIN family.|||Preautophagosomal structure http://togogenome.org/gene/7962:LOC109078199 ^@ http://purl.uniprot.org/uniprot/A0A8C1ESF0 ^@ Similarity ^@ Belongs to the PROTOR family. http://togogenome.org/gene/7962:LOC109052012 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMQ2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lysyl oxidase family.|||Contains 1 lysine tyrosylquinone.|||Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).|||The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.|||extracellular space http://togogenome.org/gene/7962:LOC109083799 ^@ http://purl.uniprot.org/uniprot/A0A8C2E8A7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/7962:anapc11 ^@ http://purl.uniprot.org/uniprot/A0A8C1MU65|||http://purl.uniprot.org/uniprot/A0A8C2HQD3 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/7962:LOC109088527 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJD3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/7962:LOC109087547 ^@ http://purl.uniprot.org/uniprot/A0A8C1DL72 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109066718 ^@ http://purl.uniprot.org/uniprot/A0A8C1EH49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109047700 ^@ http://purl.uniprot.org/uniprot/A0A8C1QEG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.|||Membrane|||Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.|||sarcolemma http://togogenome.org/gene/7962:LOC109099468 ^@ http://purl.uniprot.org/uniprot/A0A8C2JJC2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/7962:LOC109106022 ^@ http://purl.uniprot.org/uniprot/A0A8C1VB13 ^@ Function|||Similarity ^@ Belongs to the NFYB/HAP3 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. http://togogenome.org/gene/7962:LOC109052761 ^@ http://purl.uniprot.org/uniprot/A0A8C2DS71 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/7962:LOC109092990 ^@ http://purl.uniprot.org/uniprot/A0A8C1B981 ^@ Similarity ^@ Belongs to the galactose-3-O-sulfotransferase family. http://togogenome.org/gene/7962:LOC109059985 ^@ http://purl.uniprot.org/uniprot/A0A8C1QQE0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109108971 ^@ http://purl.uniprot.org/uniprot/A0A8C1VZL0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:fabp6 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLV5 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:vhl ^@ http://purl.uniprot.org/uniprot/A0A8C1I5Q5 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/7962:LOC109048182 ^@ http://purl.uniprot.org/uniprot/A0A8C1SVK1 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109101399 ^@ http://purl.uniprot.org/uniprot/A0A8C2IF70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109107975 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109105546 ^@ http://purl.uniprot.org/uniprot/A0A8C1C701 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:tmem47 ^@ http://purl.uniprot.org/uniprot/A0A8C1PCQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/7962:LOC109078163 ^@ http://purl.uniprot.org/uniprot/A0A8C1FGZ2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109113343 ^@ http://purl.uniprot.org/uniprot/A0A8C1IGM9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109050659 ^@ http://purl.uniprot.org/uniprot/A0A0C6EHM9 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109084014 ^@ http://purl.uniprot.org/uniprot/M9T9S9 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:s1pr3a ^@ http://purl.uniprot.org/uniprot/A0A8C1K282 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:arv1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EDX9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane http://togogenome.org/gene/7962:LOC109102360 ^@ http://purl.uniprot.org/uniprot/A0A8C1PH38 ^@ Similarity ^@ Belongs to the RAMP family. http://togogenome.org/gene/7962:LOC109061226 ^@ http://purl.uniprot.org/uniprot/A0A8C2GYC5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.|||Nucleus http://togogenome.org/gene/7962:LOC109061514 ^@ http://purl.uniprot.org/uniprot/A0A8C0YA21 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:smpx ^@ http://purl.uniprot.org/uniprot/A0A8C1CBY3 ^@ Function|||Similarity ^@ Belongs to the SMPX family.|||Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. http://togogenome.org/gene/7962:LOC109082419 ^@ http://purl.uniprot.org/uniprot/A0A8C1I2Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Endoplasmic reticulum lumen http://togogenome.org/gene/7962:LOC109049237 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVS6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:myod1 ^@ http://purl.uniprot.org/uniprot/O93492 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:tmem41aa ^@ http://purl.uniprot.org/uniprot/A0A8C1JF82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/7962:ptgs2a ^@ http://purl.uniprot.org/uniprot/A0A8C1QX36 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prostaglandin G/H synthase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Endoplasmic reticulum membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Microsome membrane http://togogenome.org/gene/7962:dpy30 ^@ http://purl.uniprot.org/uniprot/A0A8C2DMD8 ^@ Similarity ^@ Belongs to the dpy-30 family. http://togogenome.org/gene/7962:LOC109099401 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109082166 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3H2 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/7962:timm10 ^@ http://purl.uniprot.org/uniprot/A0A8C1YQ15 ^@ Function ^@ Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. http://togogenome.org/gene/7962:LOC109054813 ^@ http://purl.uniprot.org/uniprot/A0A8C1LJL0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7962:LOC109046798 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109085601 ^@ http://purl.uniprot.org/uniprot/A0A8C1XG38 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109112042 ^@ http://purl.uniprot.org/uniprot/A0A8C1CI32 ^@ Subunit ^@ Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family. http://togogenome.org/gene/7962:LOC109098378 ^@ http://purl.uniprot.org/uniprot/A0A8C1S9G1 ^@ Similarity ^@ Belongs to the SZRD1 family. http://togogenome.org/gene/7962:LOC109055878 ^@ http://purl.uniprot.org/uniprot/A0A089ZW73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109051515 ^@ http://purl.uniprot.org/uniprot/A0A8C1DER2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:elovl6l ^@ http://purl.uniprot.org/uniprot/A0A8C2PWN0 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL6 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||N-Glycosylated. http://togogenome.org/gene/7962:LOC109088135 ^@ http://purl.uniprot.org/uniprot/A0A8C1FI02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109056221 ^@ http://purl.uniprot.org/uniprot/A0A8C1ILB6 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:rpl18a ^@ http://purl.uniprot.org/uniprot/A0A8C1AAN0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/7962:LOC109051881 ^@ http://purl.uniprot.org/uniprot/A0A8C1PZH7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:LOC109081098 ^@ http://purl.uniprot.org/uniprot/A0A8C2AR96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 28 family.|||Nucleus http://togogenome.org/gene/7962:LOC109074661 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQS8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/7962:LOC122133917 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJQ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109093460 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tollip family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109073500 ^@ http://purl.uniprot.org/uniprot/A0A8C1YIG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORM family.|||Membrane|||Negative regulator of sphingolipid synthesis. http://togogenome.org/gene/7962:tmem258 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST5 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7962:LOC109045901 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZKY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Endoplasmic reticulum lumen http://togogenome.org/gene/7962:LOC109060101 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIP7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109048636 ^@ http://purl.uniprot.org/uniprot/A0A8C1I3B9 ^@ Similarity ^@ Belongs to the BACURD family. http://togogenome.org/gene/7962:LOC109111738 ^@ http://purl.uniprot.org/uniprot/A0A8C1EEE6 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/7962:zgc:91910 ^@ http://purl.uniprot.org/uniprot/A0A8C1W7F3 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109090723 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3V3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109088231 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMC2 ^@ Similarity ^@ Belongs to the EVA1 family. http://togogenome.org/gene/7962:si:ch73-267c23.10 ^@ http://purl.uniprot.org/uniprot/A0A8C1CVY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/7962:pde6gb ^@ http://purl.uniprot.org/uniprot/A0A8C1Q2Q8 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:nsa2 ^@ http://purl.uniprot.org/uniprot/A0A8C1XVJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/7962:LOC109102307 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7962:LOC109054072 ^@ http://purl.uniprot.org/uniprot/A0A8C0YGP8 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/7962:LOC109091601 ^@ http://purl.uniprot.org/uniprot/A0A8C1KVL9 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ATPase epsilon family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. http://togogenome.org/gene/7962:LOC109100566 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109072038 ^@ http://purl.uniprot.org/uniprot/A0A8C1J388 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/7962:LOC109084053 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:mtfp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1PM26 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/7962:LOC109099662 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y160 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:snrpg ^@ http://purl.uniprot.org/uniprot/A0A8C1VGE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/7962:LOC109099600 ^@ http://purl.uniprot.org/uniprot/A0A8C1S5A3 ^@ Similarity|||Subunit ^@ Belongs to the GILT family.|||Dimer; disulfide-linked. http://togogenome.org/gene/7962:LOC109108793 ^@ http://purl.uniprot.org/uniprot/A0A8C2IT49 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/7962:vhll ^@ http://purl.uniprot.org/uniprot/A0A8C1CM31 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/7962:triap1 ^@ http://purl.uniprot.org/uniprot/A0A8C2PXU4 ^@ Similarity ^@ Belongs to the TRIAP1/MDM35 family. http://togogenome.org/gene/7962:nr6a1a ^@ http://purl.uniprot.org/uniprot/A0A8C1I8N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:chst2a ^@ http://purl.uniprot.org/uniprot/A0A8C1UC39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109061846 ^@ http://purl.uniprot.org/uniprot/A0A8C1K7J0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/7962:LOC109098117 ^@ http://purl.uniprot.org/uniprot/A0A8C1BC72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the distal-less homeobox family.|||Nucleus http://togogenome.org/gene/7962:ndufa8 ^@ http://purl.uniprot.org/uniprot/A0A8C1WTS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:gsk3aa ^@ http://purl.uniprot.org/uniprot/A0A8C1ACN2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/7962:LOC109049097 ^@ http://purl.uniprot.org/uniprot/A0A8C1BS02 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109050990 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0M8|||http://purl.uniprot.org/uniprot/A0A8C2D4Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/7962:LOC109103250 ^@ http://purl.uniprot.org/uniprot/A0A8C1R5R5 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:hmgn3 ^@ http://purl.uniprot.org/uniprot/A0A8C1F1N3|||http://purl.uniprot.org/uniprot/A0A8C2AQX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGN family.|||Nucleus http://togogenome.org/gene/7962:LOC109113213 ^@ http://purl.uniprot.org/uniprot/A0A8C1W7Q6 ^@ Similarity ^@ Belongs to the FAM110 family. http://togogenome.org/gene/7962:mdfic2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BX95 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/7962:LOC109081331 ^@ http://purl.uniprot.org/uniprot/A0A8C1FI41|||http://purl.uniprot.org/uniprot/A0A8C1FMR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLF family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109085074 ^@ http://purl.uniprot.org/uniprot/E7FL10 ^@ Similarity ^@ Belongs to the nanos family. http://togogenome.org/gene/7962:LOC109045421 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||May be involved in vesicle transport between the ER and the Golgi complex.|||Membrane http://togogenome.org/gene/7962:tmem38a ^@ http://purl.uniprot.org/uniprot/A0A8C1PXL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane|||Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. http://togogenome.org/gene/7962:LOC109080882 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:cd8b ^@ http://purl.uniprot.org/uniprot/A8HDP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109046102 ^@ http://purl.uniprot.org/uniprot/A0A8C1JA22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic mitochondrial porin family.|||Cell membrane|||Membrane|||Membrane raft http://togogenome.org/gene/7962:LOC109097720 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZMF2 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/7962:LOC109065923 ^@ http://purl.uniprot.org/uniprot/A0A8C1CUI9 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:LOC109058449 ^@ http://purl.uniprot.org/uniprot/A0A8C2CD64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the apolipoprotein C1 family.|||Secreted http://togogenome.org/gene/7962:LOC109099632 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q9M1 ^@ Function|||Similarity ^@ Belongs to the pex2/pex10/pex12 family.|||Somewhat implicated in the biogenesis of peroxisomes. http://togogenome.org/gene/7962:LOC109068259 ^@ http://purl.uniprot.org/uniprot/A0A8C1DU74 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/7962:LOC109059497 ^@ http://purl.uniprot.org/uniprot/A0A8C2DBG7 ^@ Function|||Subcellular Location Annotation ^@ Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.|||cell cortex|||cytoskeleton http://togogenome.org/gene/7962:utp15 ^@ http://purl.uniprot.org/uniprot/A0A8C1AHV0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109092141 ^@ http://purl.uniprot.org/uniprot/A0A8C1JSB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ITPRIP family.|||Cell membrane|||Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/7962:LOC109050034 ^@ http://purl.uniprot.org/uniprot/A0A8C1MSJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109067880 ^@ http://purl.uniprot.org/uniprot/A0A8C2F084 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/7962:LOC109052983 ^@ http://purl.uniprot.org/uniprot/A0A8C1BU29 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:zgc:153993 ^@ http://purl.uniprot.org/uniprot/A0A8C2EFA9 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/7962:LOC109070211 ^@ http://purl.uniprot.org/uniprot/A0A8C1EK78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Bcl-2 family.|||Membrane http://togogenome.org/gene/7962:LOC109102876 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZB4 ^@ Similarity ^@ Belongs to the SKI family. http://togogenome.org/gene/7962:crygmx ^@ http://purl.uniprot.org/uniprot/A0A8C1I9M6 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109052033 ^@ http://purl.uniprot.org/uniprot/A0A8C1GS07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/7962:LOC109049730 ^@ http://purl.uniprot.org/uniprot/A0A8C2IQI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholamban family.|||Endoplasmic reticulum membrane|||Membrane|||Mitochondrion membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109081356 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109108912 ^@ http://purl.uniprot.org/uniprot/A0A8C1C0G3 ^@ Similarity ^@ Belongs to the phospholipase D family. http://togogenome.org/gene/7962:LOC109108972 ^@ http://purl.uniprot.org/uniprot/A0A8C1K9Z2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109060944 ^@ http://purl.uniprot.org/uniprot/A0A8C1YU78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:sfr1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ST18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SFR1/MEI5 family.|||Nucleus http://togogenome.org/gene/7962:LOC109108674 ^@ http://purl.uniprot.org/uniprot/A0A8C1GMQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAR6 family.|||Cytoplasm|||tight junction http://togogenome.org/gene/7962:LOC109065570 ^@ http://purl.uniprot.org/uniprot/A0A8C1YCP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109051833 ^@ http://purl.uniprot.org/uniprot/A0A8C1C5F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFC2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109046662 ^@ http://purl.uniprot.org/uniprot/A0A8C2HXS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:slc25a35 ^@ http://purl.uniprot.org/uniprot/A0A8C1YXW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:gadd45aa ^@ http://purl.uniprot.org/uniprot/A0A8C2ADP0 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109069654 ^@ http://purl.uniprot.org/uniprot/A0A8C1CVR0 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109063048 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQ33 ^@ Similarity ^@ Belongs to the protease inhibitor I47 (latexin) family. http://togogenome.org/gene/7962:LOC109091679 ^@ http://purl.uniprot.org/uniprot/A0A8C1C804 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.|||Membrane|||Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.|||sarcolemma http://togogenome.org/gene/7962:serp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1T0G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane|||May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.|||Membrane http://togogenome.org/gene/7962:dok1b ^@ http://purl.uniprot.org/uniprot/A0A8C1F9F6 ^@ Similarity ^@ Belongs to the DOK family. Type A subfamily. http://togogenome.org/gene/7962:cryba1l1 ^@ http://purl.uniprot.org/uniprot/A0A8C1J5Y6 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109064869 ^@ http://purl.uniprot.org/uniprot/A0A8C1DB25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||May be involved in vesicle transport between the ER and the Golgi complex.|||Membrane http://togogenome.org/gene/7962:LOC109053026 ^@ http://purl.uniprot.org/uniprot/A0A8C1H9F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/7962:pthlha ^@ http://purl.uniprot.org/uniprot/A0A8C1A465 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||Secreted http://togogenome.org/gene/7962:LOC109052889 ^@ http://purl.uniprot.org/uniprot/A0A8C1A876 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:rarab ^@ http://purl.uniprot.org/uniprot/A0A8C1XN81 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.|||Nucleus http://togogenome.org/gene/7962:LOC109072494 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQG6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:snrpf ^@ http://purl.uniprot.org/uniprot/A0A8C2EN87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/7962:adora2ab ^@ http://purl.uniprot.org/uniprot/A0A8C1LVV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. http://togogenome.org/gene/7962:LOC109075394 ^@ http://purl.uniprot.org/uniprot/A0A8C1EX98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Might be involved in growth regulation, and in myelinization in the peripheral nervous system. http://togogenome.org/gene/7962:LOC109054023 ^@ http://purl.uniprot.org/uniprot/A0A8C1LTY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109056215 ^@ http://purl.uniprot.org/uniprot/A0A8C1IKY4 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109112135 ^@ http://purl.uniprot.org/uniprot/A0A8C1F1R8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/7962:LOC109075184 ^@ http://purl.uniprot.org/uniprot/A0A8C1RG06 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus|||Secreted http://togogenome.org/gene/7962:fgf11b ^@ http://purl.uniprot.org/uniprot/A0A8C1GLV8 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109110012 ^@ http://purl.uniprot.org/uniprot/A0A8C1BX64 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109109370 ^@ http://purl.uniprot.org/uniprot/A0A8C1N1G0 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/7962:LOC109065974 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZXR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat peroxin-7 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109076866 ^@ http://purl.uniprot.org/uniprot/Q71U52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/7962:LOC109066066 ^@ http://purl.uniprot.org/uniprot/A0A8C1CIY6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109060895 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked.|||Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales. http://togogenome.org/gene/7962:LOC109087058 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:slc39a5 ^@ http://purl.uniprot.org/uniprot/A0A089ZW72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109106890 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y7R8 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109080524 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJJ0 ^@ Similarity|||Subunit ^@ Belongs to the CutA family.|||Homotrimer. http://togogenome.org/gene/7962:LOC109076276 ^@ http://purl.uniprot.org/uniprot/A0A8C1CM63 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||gap junction http://togogenome.org/gene/7962:ube2al ^@ http://purl.uniprot.org/uniprot/A0A8C1A544 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109046577 ^@ http://purl.uniprot.org/uniprot/A0A8C2ITY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:fpr1 ^@ http://purl.uniprot.org/uniprot/A0A8C2EIR0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:isy1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CXE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109056297 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJ91 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/7962:LOC109087857 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2L9 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Plays a role in the process of neurogenesis. http://togogenome.org/gene/7962:LOC109104869 ^@ http://purl.uniprot.org/uniprot/A0A8C0YF54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLF family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109048474 ^@ http://purl.uniprot.org/uniprot/A0A8C1EUF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109102522 ^@ http://purl.uniprot.org/uniprot/A0A8C1WGE1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109105951 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFZ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/7962:ciao2a ^@ http://purl.uniprot.org/uniprot/A0A8C1QBU3 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/7962:ric3b ^@ http://purl.uniprot.org/uniprot/A0A8C1XW79 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/7962:LOC109098463 ^@ http://purl.uniprot.org/uniprot/A0A8C2CDT1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109057288 ^@ http://purl.uniprot.org/uniprot/A0A8C1FRT4|||http://purl.uniprot.org/uniprot/A0A8C1FSG9 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/7962:gpr107 ^@ http://purl.uniprot.org/uniprot/A0A8C1JA52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:gtf2e1 ^@ http://purl.uniprot.org/uniprot/A0A8C1KWJ6 ^@ Function|||Similarity ^@ Belongs to the TFIIE alpha subunit family.|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. http://togogenome.org/gene/7962:ucn3l ^@ http://purl.uniprot.org/uniprot/A0A8C1AEL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.|||Binds with high affinity to CRF receptors 2-alpha and 2-beta.|||Secreted|||Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. http://togogenome.org/gene/7962:LOC109091732 ^@ http://purl.uniprot.org/uniprot/A0A8C1A975 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ May interact with TSPO.|||Mitochondrion|||Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. http://togogenome.org/gene/7962:LOC109057357 ^@ http://purl.uniprot.org/uniprot/A0A8C1NX25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/7962:LOC109060060 ^@ http://purl.uniprot.org/uniprot/A0A8C1JV59 ^@ Similarity ^@ Belongs to the UQCRH/QCR6 family. http://togogenome.org/gene/7962:rab38c ^@ http://purl.uniprot.org/uniprot/A0A8C1FRG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:LOC109076267 ^@ http://purl.uniprot.org/uniprot/A0A8C1CM42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109100693 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANW7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109050489 ^@ http://purl.uniprot.org/uniprot/A0A8C0YFE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.|||Secreted http://togogenome.org/gene/7962:dusp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1KJH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109070675 ^@ http://purl.uniprot.org/uniprot/A0A8C1V0L5 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7962:LOC109068050 ^@ http://purl.uniprot.org/uniprot/A0A8C1BED2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109076265 ^@ http://purl.uniprot.org/uniprot/A0A8C1VEH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:yod1 ^@ http://purl.uniprot.org/uniprot/A0A8C1I2S6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin. http://togogenome.org/gene/7962:LOC109058458 ^@ http://purl.uniprot.org/uniprot/A0A8C1CPG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the apolipoprotein C2 family.|||Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.|||Secreted http://togogenome.org/gene/7962:LOC109101629 ^@ http://purl.uniprot.org/uniprot/A0A8C1V6Y8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/7962:LOC109099009 ^@ http://purl.uniprot.org/uniprot/A0A8C0XYA0 ^@ Function|||Similarity ^@ Belongs to the intermediate filament family.|||Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. http://togogenome.org/gene/7962:kansl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1GQM6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.|||Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.|||Nucleus http://togogenome.org/gene/7962:crybb2 ^@ http://purl.uniprot.org/uniprot/A0A8C1P023 ^@ Function|||Similarity|||Subunit ^@ Belongs to the beta/gamma-crystallin family.|||Crystallins are the dominant structural components of the vertebrate eye lens.|||Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms. http://togogenome.org/gene/7962:casp23 ^@ http://purl.uniprot.org/uniprot/A0A8C1CV67 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:LOC109061199 ^@ http://purl.uniprot.org/uniprot/A0A8C1E2I4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/7962:LOC109065704 ^@ http://purl.uniprot.org/uniprot/A0A089ZWW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109082370 ^@ http://purl.uniprot.org/uniprot/Q2PFL1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit.|||Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen. http://togogenome.org/gene/7962:LOC109073036 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMC1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109076509 ^@ http://purl.uniprot.org/uniprot/A0A8C1IP86 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109057987 ^@ http://purl.uniprot.org/uniprot/A0A8C2K1I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane http://togogenome.org/gene/7962:tefa ^@ http://purl.uniprot.org/uniprot/A0A8C1XIR2|||http://purl.uniprot.org/uniprot/A0A8C1XLF8|||http://purl.uniprot.org/uniprot/A0A8C2KLU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. PAR subfamily.|||Nucleus http://togogenome.org/gene/7962:mrpl11 ^@ http://purl.uniprot.org/uniprot/A0A8C1I627 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/7962:kcnj15 ^@ http://purl.uniprot.org/uniprot/A0A8C1PN83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:med20 ^@ http://purl.uniprot.org/uniprot/A0A8C1HM52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 20 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109075504 ^@ http://purl.uniprot.org/uniprot/A0A8C2EDB7 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/7962:tpm4b ^@ http://purl.uniprot.org/uniprot/A0A8C1J858 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109084408 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MLLT11 family.|||Nucleus|||centrosome http://togogenome.org/gene/7962:pou4f3 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7962:LOC109101636 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109070084 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1F2|||http://purl.uniprot.org/uniprot/A0A8C2ANJ8 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/7962:LOC109073478 ^@ http://purl.uniprot.org/uniprot/A0A8C1P4A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/7962:zmp:0000001138 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-2-microglobulin family.|||Secreted http://togogenome.org/gene/7962:LOC109095475 ^@ http://purl.uniprot.org/uniprot/A0A8C1J0M2|||http://purl.uniprot.org/uniprot/A0A8C2AIP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109087909 ^@ http://purl.uniprot.org/uniprot/A0A8C1FC39 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109046692 ^@ http://purl.uniprot.org/uniprot/A0A8C2DZ37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:zgc:112052 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the C19orf12 family.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109055298 ^@ http://purl.uniprot.org/uniprot/A0A8C0YUD4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109110116 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6D1 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109072140 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLV9 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109081097 ^@ http://purl.uniprot.org/uniprot/A0A8C1F0T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109110302 ^@ http://purl.uniprot.org/uniprot/A0A8C1QG68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/7962:anapc16 ^@ http://purl.uniprot.org/uniprot/A0A8C1LGE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APC16 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.|||Cytoplasm|||Nucleus|||kinetochore http://togogenome.org/gene/7962:lifrb ^@ http://purl.uniprot.org/uniprot/A0A8C1EAP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type I cytokine receptor family. Type 2 subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109100736 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109079209 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERY6 ^@ Similarity ^@ Belongs to the dermatopontin family. http://togogenome.org/gene/7962:LOC109097849 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:icam1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CT17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the immunoglobulin superfamily. ICAM family.|||Membrane http://togogenome.org/gene/7962:iah1 ^@ http://purl.uniprot.org/uniprot/A0A8C1B0X3 ^@ Function|||Similarity ^@ Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.|||Probable lipase. http://togogenome.org/gene/7962:LOC109100747 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIU9|||http://purl.uniprot.org/uniprot/A0A8C1YCV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109084620 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y157 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NCBP1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109073331 ^@ http://purl.uniprot.org/uniprot/A0A8C1US35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/7962:LOC109051009 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIB2 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:sostdc1b ^@ http://purl.uniprot.org/uniprot/A0A8C1S811 ^@ Caution|||Similarity ^@ Belongs to the sclerostin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109065675 ^@ http://purl.uniprot.org/uniprot/A0A8C1NAU2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109094615 ^@ http://purl.uniprot.org/uniprot/A0A8C1CX73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109070949 ^@ http://purl.uniprot.org/uniprot/A0A8C1N654 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SIX/Sine oculis homeobox family.|||Nucleus http://togogenome.org/gene/7962:smarcb1b ^@ http://purl.uniprot.org/uniprot/A0A8C1IKW8|||http://purl.uniprot.org/uniprot/A0A8C2CI33 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNF5 family.|||Component of the multiprotein chromatin-remodeling complexes SWI/SNF.|||Nucleus http://togogenome.org/gene/7962:LOC109105871 ^@ http://purl.uniprot.org/uniprot/A0A8C1WBN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. ABHD16 family.|||Membrane http://togogenome.org/gene/7962:LOC109059304 ^@ http://purl.uniprot.org/uniprot/A0A8C1H322 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPRE family.|||centrosome|||spindle pole http://togogenome.org/gene/7962:LOC109104134 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BLOC1S3 family.|||Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).|||Cytoplasm http://togogenome.org/gene/7962:LOC109074210 ^@ http://purl.uniprot.org/uniprot/A0A8C1F086 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:med28 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 28 family.|||Nucleus http://togogenome.org/gene/7962:LOC109111606 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADL6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/7962:LOC109051417 ^@ http://purl.uniprot.org/uniprot/A0A8C1F904 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109109357 ^@ http://purl.uniprot.org/uniprot/A0A8C2E8C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor T2R family.|||Membrane http://togogenome.org/gene/7962:LOC109104686 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:drd3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109100416 ^@ http://purl.uniprot.org/uniprot/A0A8C1N2I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Membrane http://togogenome.org/gene/7962:LOC109056476 ^@ http://purl.uniprot.org/uniprot/A0A8C1FT63 ^@ Similarity ^@ Belongs to the CDK2AP family. http://togogenome.org/gene/7962:LOC109085576 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:ccdc85al ^@ http://purl.uniprot.org/uniprot/A0A8C1HKU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC85 family.|||adherens junction http://togogenome.org/gene/7962:shhb ^@ http://purl.uniprot.org/uniprot/A0A8C1XEA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/7962:LOC109080140 ^@ http://purl.uniprot.org/uniprot/A0A8C1FUY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/7962:LOC109072578 ^@ http://purl.uniprot.org/uniprot/A0A8C1KZS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109080550 ^@ http://purl.uniprot.org/uniprot/A0A8C1R9D0 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109098519 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasm|||Membrane|||This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.|||caveola http://togogenome.org/gene/7962:LOC109070078 ^@ http://purl.uniprot.org/uniprot/A0A8C1P0Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAVIN family.|||caveola|||sarcomere http://togogenome.org/gene/7962:LOC109050551 ^@ http://purl.uniprot.org/uniprot/A0A8C1IRT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109056214 ^@ http://purl.uniprot.org/uniprot/A0A8C1ILN5 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109060476 ^@ http://purl.uniprot.org/uniprot/A0A8C1RZ56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:hspb15 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERP0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:cap1 ^@ http://purl.uniprot.org/uniprot/A0A8C2G6A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAP family.|||Cell membrane http://togogenome.org/gene/7962:LOC109091660 ^@ http://purl.uniprot.org/uniprot/A0A8C1C7F6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.|||Nucleus|||Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. http://togogenome.org/gene/7962:LOC109069647 ^@ http://purl.uniprot.org/uniprot/A0A8C1HI60 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/7962:rpf1 ^@ http://purl.uniprot.org/uniprot/A0A8C2EIC5 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109052742 ^@ http://purl.uniprot.org/uniprot/A0A8C1YFB6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109052091 ^@ http://purl.uniprot.org/uniprot/A0A8C1QGF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.|||centrosome http://togogenome.org/gene/7962:LOC109102491 ^@ http://purl.uniprot.org/uniprot/A0A8C1T875 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/7962:mrps31 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS31 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109092280 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLK0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109058981 ^@ http://purl.uniprot.org/uniprot/A0A8C1DF40 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/7962:slc10a7 ^@ http://purl.uniprot.org/uniprot/A0A8C1HSN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.|||Cell membrane|||Does not show transport activity towards bile acids or steroid sulfates.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane http://togogenome.org/gene/7962:gmfg ^@ http://purl.uniprot.org/uniprot/Q9IBG6 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. GMF subfamily. http://togogenome.org/gene/7962:ptprna ^@ http://purl.uniprot.org/uniprot/A0A8C1JNW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.|||Membrane|||secretory vesicle membrane http://togogenome.org/gene/7962:LOC109075574 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:zgc:101783 ^@ http://purl.uniprot.org/uniprot/A0A8C0XVR6|||http://purl.uniprot.org/uniprot/A0A8C0Y2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/7962:LOC109067665 ^@ http://purl.uniprot.org/uniprot/A0A8C1BV88 ^@ Similarity ^@ Belongs to the CDPF1 family. http://togogenome.org/gene/7962:cdc42ep1a ^@ http://purl.uniprot.org/uniprot/A0A8C1CYB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109065254 ^@ http://purl.uniprot.org/uniprot/A0A8C2JG89 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109095720 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJ03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor T2R family.|||Membrane http://togogenome.org/gene/7962:LOC109066845 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAC8 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/7962:dtnbp1a ^@ http://purl.uniprot.org/uniprot/A0A8C1NBU4 ^@ Similarity ^@ Belongs to the dysbindin family. http://togogenome.org/gene/7962:LOC109069215 ^@ http://purl.uniprot.org/uniprot/A0A8C1MZQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INKA family.|||Nucleus http://togogenome.org/gene/7962:LOC109056358 ^@ http://purl.uniprot.org/uniprot/A0A8C1EN87 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:ccni ^@ http://purl.uniprot.org/uniprot/A0A8C1HTH9 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109112653 ^@ http://purl.uniprot.org/uniprot/A0A8C1DXS9 ^@ Similarity ^@ Belongs to the fl(2)d family. http://togogenome.org/gene/7962:map4l ^@ http://purl.uniprot.org/uniprot/A0A8C1HN92 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/7962:prickle2a ^@ http://purl.uniprot.org/uniprot/A0A8C1HS75 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/7962:LOC109093559 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIT5 ^@ Function|||Similarity ^@ Belongs to the metallothionein superfamily. Type 1 family.|||Metallothioneins have a high content of cysteine residues that bind various heavy metals. http://togogenome.org/gene/7962:amer3 ^@ http://purl.uniprot.org/uniprot/A0A8C1FGI4 ^@ Similarity ^@ Belongs to the Amer family. http://togogenome.org/gene/7962:LOC109113390 ^@ http://purl.uniprot.org/uniprot/C5HG68 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109057406 ^@ http://purl.uniprot.org/uniprot/A0A8C1BUU7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/7962:LOC109082790 ^@ http://purl.uniprot.org/uniprot/A0A8C1D1H6 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/7962:LOC109046615 ^@ http://purl.uniprot.org/uniprot/A0A8C2HRM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109072245 ^@ http://purl.uniprot.org/uniprot/A0A8C1R778 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.|||Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.|||Nucleus http://togogenome.org/gene/7962:arpc3 ^@ http://purl.uniprot.org/uniprot/A0A8C2CR45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/7962:kcnab2a ^@ http://purl.uniprot.org/uniprot/A0A8C1E4N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shaker potassium channel beta subunit family.|||Cell membrane|||Cytoplasm|||Membrane http://togogenome.org/gene/7962:LOC109106141 ^@ http://purl.uniprot.org/uniprot/A0A8C0XVA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109092403 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109101499 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Endoplasmic reticulum membrane|||Membrane|||Peroxisome membrane|||Vesicle http://togogenome.org/gene/7962:LOC109056206 ^@ http://purl.uniprot.org/uniprot/M9T843 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109045172 ^@ http://purl.uniprot.org/uniprot/A0A8C1BCG4 ^@ Similarity ^@ Belongs to the FAM216 family. http://togogenome.org/gene/7962:LOC109086730 ^@ http://purl.uniprot.org/uniprot/A0A8C1R746 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ripply family.|||Nucleus http://togogenome.org/gene/7962:hexdc ^@ http://purl.uniprot.org/uniprot/A0A8C1A1A2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/7962:cdc42se2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC42SE/SPEC family.|||Cell membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/7962:LOC109085271 ^@ http://purl.uniprot.org/uniprot/A0A8C1WJW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.|||Secreted http://togogenome.org/gene/7962:gadd45bb ^@ http://purl.uniprot.org/uniprot/A0A8C1TRB0 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109086876 ^@ http://purl.uniprot.org/uniprot/A0A8C2KYV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/7962:LOC109061375 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNC3 ^@ Similarity ^@ Belongs to the IL-6 superfamily. http://togogenome.org/gene/7962:LOC109090436 ^@ http://purl.uniprot.org/uniprot/A0A8C1A9B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. http://togogenome.org/gene/7962:LOC109097105 ^@ http://purl.uniprot.org/uniprot/A0A8C1CID6 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/7962:LOC109102382 ^@ http://purl.uniprot.org/uniprot/A0A8C1UC88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom5 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109092888 ^@ http://purl.uniprot.org/uniprot/A0A8C1T1J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Endosome membrane|||Late endosome membrane http://togogenome.org/gene/7962:gcnt7 ^@ http://purl.uniprot.org/uniprot/A0A8C1EHW3 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109107167 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUJ8|||http://purl.uniprot.org/uniprot/A0A8C2FPX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galanin family.|||Secreted http://togogenome.org/gene/7962:LOC109070353 ^@ http://purl.uniprot.org/uniprot/A0A8C1EN01 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109081623 ^@ http://purl.uniprot.org/uniprot/A0A8C1HBS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/7962:LOC109098988 ^@ http://purl.uniprot.org/uniprot/A0A8C1P4Q6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109048145 ^@ http://purl.uniprot.org/uniprot/A0A8C1JM71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109087779 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNG0 ^@ Similarity ^@ Belongs to the PRKRIP1 family. http://togogenome.org/gene/7962:LOC109076279 ^@ http://purl.uniprot.org/uniprot/A0A8C1CKQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:cmc4 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANW3 ^@ Similarity ^@ Belongs to the CMC4 family. http://togogenome.org/gene/7962:LOC109089109 ^@ http://purl.uniprot.org/uniprot/A0A8C1LV87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109075997 ^@ http://purl.uniprot.org/uniprot/A0A8C2PMT0 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109066501 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). http://togogenome.org/gene/7962:LOC109047254 ^@ http://purl.uniprot.org/uniprot/A0A8C1YD55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP11 family.|||Mitochondrion http://togogenome.org/gene/7962:ywhah ^@ http://purl.uniprot.org/uniprot/A0A8C2KWL9 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:gpr137ba ^@ http://purl.uniprot.org/uniprot/A0A8C2BM67 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/7962:ostc ^@ http://purl.uniprot.org/uniprot/A0A8C1NV49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OSTC family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7962:LOC109097118 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8I9 ^@ Similarity ^@ Belongs to the chondromodulin-1 family. http://togogenome.org/gene/7962:LOC109097131 ^@ http://purl.uniprot.org/uniprot/A0A8C1TFF4 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109056526 ^@ http://purl.uniprot.org/uniprot/A0A8C2F4W3 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:dscc1 ^@ http://purl.uniprot.org/uniprot/A0A8C1RXQ8 ^@ Similarity ^@ Belongs to the DCC1 family. http://togogenome.org/gene/7962:LOC109083117 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFD7 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109058538 ^@ http://purl.uniprot.org/uniprot/A0A8C2B1D6 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109097465 ^@ http://purl.uniprot.org/uniprot/A0A8C2I8V8 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/7962:LOC122133971 ^@ http://purl.uniprot.org/uniprot/A0A8C1SSB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109091505 ^@ http://purl.uniprot.org/uniprot/A0A8C0YT49 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC3 family.|||Component of the ER membrane protein complex (EMC).|||Membrane http://togogenome.org/gene/7962:LOC109054542 ^@ http://purl.uniprot.org/uniprot/A0A8C0YFG4 ^@ Function ^@ May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. http://togogenome.org/gene/7962:LOC109055292 ^@ http://purl.uniprot.org/uniprot/A0A8C0YNQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/7962:LOC109066114 ^@ http://purl.uniprot.org/uniprot/A0A8C1D5P3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1B family.|||Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.|||Peroxisome|||The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity. http://togogenome.org/gene/7962:LOC109097397 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRKRA family.|||perinuclear region http://togogenome.org/gene/7962:ube2d4 ^@ http://purl.uniprot.org/uniprot/A0A8C1UBE4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109102495 ^@ http://purl.uniprot.org/uniprot/Q0GZP0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:mmgt1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EC18 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane magnesium transporter (TC 1.A.67) family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport. http://togogenome.org/gene/7962:LOC109079225 ^@ http://purl.uniprot.org/uniprot/A0A8C1ES81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109060155 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galanin family.|||Secreted http://togogenome.org/gene/7962:vegfaa ^@ http://purl.uniprot.org/uniprot/A0A8C1A1F1 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/7962:LOC109066535 ^@ http://purl.uniprot.org/uniprot/A0A8C1PRL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/7962:LOC109104723 ^@ http://purl.uniprot.org/uniprot/A0A8C1PIF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-13 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/7962:LOC109062501 ^@ http://purl.uniprot.org/uniprot/A0A0K2RVU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/7962:metrnla ^@ http://purl.uniprot.org/uniprot/A0A8C1C1U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the meteorin family.|||Secreted http://togogenome.org/gene/7962:LOC109100142 ^@ http://purl.uniprot.org/uniprot/A0A8C1YE36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109110357 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/7962:LOC109048950 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobindin family.|||Cytoplasm|||Secreted|||cis-Golgi network membrane http://togogenome.org/gene/7962:LOC109104068 ^@ http://purl.uniprot.org/uniprot/A0A8C1NVR6 ^@ Similarity ^@ Belongs to the SNAPIN family. http://togogenome.org/gene/7962:mfsd14a1 ^@ http://purl.uniprot.org/uniprot/A0A8C2GU79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/7962:LOC109087215 ^@ http://purl.uniprot.org/uniprot/A0A8C1QVV4 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/7962:LOC109101607 ^@ http://purl.uniprot.org/uniprot/A0A8C0YM27 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109094637 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIT2|||http://purl.uniprot.org/uniprot/A0A8C1HM40 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109090909 ^@ http://purl.uniprot.org/uniprot/A0A8C1NMF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heparin-binding growth factors family.|||Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.|||Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.|||Secreted http://togogenome.org/gene/7962:LOC109071330 ^@ http://purl.uniprot.org/uniprot/A0A8C2EDM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:sept5b ^@ http://purl.uniprot.org/uniprot/A0A8C1S0B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109072888 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109083574 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2Y8|||http://purl.uniprot.org/uniprot/A0A8C1MWG4 ^@ Similarity ^@ Belongs to the FAM219 family. http://togogenome.org/gene/7962:LOC109068355 ^@ http://purl.uniprot.org/uniprot/A0A8C1CWP5 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/7962:LOC109081280 ^@ http://purl.uniprot.org/uniprot/A0A8C1D2Z0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with ARRB1.|||Membrane http://togogenome.org/gene/7962:gnb3a ^@ http://purl.uniprot.org/uniprot/A0A8C1VH73 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/7962:ndufa3 ^@ http://purl.uniprot.org/uniprot/A0A8C1F1F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA3 subunit family.|||Complex I is composed of 45 different subunits.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:enkd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AL60 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/7962:LOC109063678 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z7E3 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:KEF38_p07 ^@ http://purl.uniprot.org/uniprot/P15952|||http://purl.uniprot.org/uniprot/W5TY45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109059081 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRM6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:metrnlb ^@ http://purl.uniprot.org/uniprot/A0A8C1ERB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the meteorin family.|||Secreted http://togogenome.org/gene/7962:ppcs ^@ http://purl.uniprot.org/uniprot/A0A8C1BR30 ^@ Similarity ^@ Belongs to the PPC synthetase family. http://togogenome.org/gene/7962:pde6ga ^@ http://purl.uniprot.org/uniprot/A5LG12 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109046442 ^@ http://purl.uniprot.org/uniprot/A0A8C2K0Q2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS21 family.|||Component of the 40S small ribosomal subunit.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/7962:LOC109057427 ^@ http://purl.uniprot.org/uniprot/A0A8C1HY05 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109051135 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDH1 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:LOC109051867 ^@ http://purl.uniprot.org/uniprot/A0A8C1XYK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/7962:LOC109050098 ^@ http://purl.uniprot.org/uniprot/A0A8C1FWB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109083894 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJQ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:si:ch1073-280e3.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AU11 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109081550 ^@ http://purl.uniprot.org/uniprot/A0A8C1UM02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/7962:ehd3 ^@ http://purl.uniprot.org/uniprot/A0A8C2BYD7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane|||Recycling endosome membrane|||cilium membrane http://togogenome.org/gene/7962:gpc1a ^@ http://purl.uniprot.org/uniprot/A0A8C1ABP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan that bears heparan sulfate.|||extracellular space http://togogenome.org/gene/7962:LOC109104141 ^@ http://purl.uniprot.org/uniprot/A0A8C1R3I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/7962:LOC109053326 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8Z1 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/7962:LOC109078724 ^@ http://purl.uniprot.org/uniprot/A0A8C1RDB9 ^@ Function|||Similarity|||Subunit ^@ Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.|||Belongs to the fucolectin family.|||Homotrimer. http://togogenome.org/gene/7962:LOC109084701 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y5S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:lsm6 ^@ http://purl.uniprot.org/uniprot/A0A8C2HS78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109088608 ^@ http://purl.uniprot.org/uniprot/A0A8C1BW74 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/7962:lcn15 ^@ http://purl.uniprot.org/uniprot/A0A8C2BSR2 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109046530 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Cell membrane|||Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.|||Membrane http://togogenome.org/gene/7962:LOC109065171 ^@ http://purl.uniprot.org/uniprot/A0A8C1W0E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPIN/STSY family.|||Nucleus http://togogenome.org/gene/7962:LOC109112250 ^@ http://purl.uniprot.org/uniprot/A0A8C1DSS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the distal-less homeobox family.|||Nucleus http://togogenome.org/gene/7962:pold2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FMQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase delta/II small subunit family.|||Nucleus http://togogenome.org/gene/7962:LOC109079202 ^@ http://purl.uniprot.org/uniprot/A0A8C1NR31 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/7962:LOC109102149 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABC9 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/7962:LOC109090051 ^@ http://purl.uniprot.org/uniprot/A0A8C1RZ43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109064007 ^@ http://purl.uniprot.org/uniprot/A0A8C2I7I9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:LOC109097339 ^@ http://purl.uniprot.org/uniprot/A0A8C1GKR9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109048968 ^@ http://purl.uniprot.org/uniprot/A0A8C0YTH0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/7962:prkar1ab ^@ http://purl.uniprot.org/uniprot/A0A8C1M261 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109046471 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/7962:slc43a3b ^@ http://purl.uniprot.org/uniprot/A0A8C1IFN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109093068 ^@ http://purl.uniprot.org/uniprot/A0A8C2ARN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7962:arf4b ^@ http://purl.uniprot.org/uniprot/A0A8C1DMR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:mrpl51 ^@ http://purl.uniprot.org/uniprot/A0A8C1ST39 ^@ Similarity ^@ Belongs to the mitochondrion-specific ribosomal protein mL51 family. http://togogenome.org/gene/7962:bcl2b ^@ http://purl.uniprot.org/uniprot/A0A8C1C3R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Bcl-2 family.|||Cytoplasm|||Endoplasmic reticulum membrane|||Membrane|||Mitochondrion outer membrane|||Nucleus membrane http://togogenome.org/gene/7962:LOC109096851 ^@ http://purl.uniprot.org/uniprot/A0A8C1DTE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109069171 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 99 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109065046 ^@ http://purl.uniprot.org/uniprot/A0A8C1D7E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.|||Belongs to the mitochondrion-specific ribosomal protein mL64 family.|||Mitochondrion|||Nucleus http://togogenome.org/gene/7962:scamp5a ^@ http://purl.uniprot.org/uniprot/A0A8C1VLG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/7962:LOC109090788 ^@ http://purl.uniprot.org/uniprot/A0A8C0XYF8 ^@ Similarity|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer. http://togogenome.org/gene/7962:LOC109064247 ^@ http://purl.uniprot.org/uniprot/A0A8C2JIP4 ^@ Subcellular Location Annotation ^@ Z line http://togogenome.org/gene/7962:LOC109077280 ^@ http://purl.uniprot.org/uniprot/A0A8C1EFL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109068898 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:qki2 ^@ http://purl.uniprot.org/uniprot/A0A8C1L4D9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:map1lc3b ^@ http://purl.uniprot.org/uniprot/A0A8C1K3H7 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109048898 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNJ8 ^@ Similarity ^@ Belongs to the neuritin family. http://togogenome.org/gene/7962:LOC109078702 ^@ http://purl.uniprot.org/uniprot/A0A8C1D855 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109077410 ^@ http://purl.uniprot.org/uniprot/A0A8C1KWX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109085540 ^@ http://purl.uniprot.org/uniprot/A0A8C1D935 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109056682 ^@ http://purl.uniprot.org/uniprot/A0A8C1C344 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM175 family. Abraxas subfamily.|||Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.|||Nucleus http://togogenome.org/gene/7962:LOC122133993 ^@ http://purl.uniprot.org/uniprot/A0A8C2JIW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/7962:LOC109088831 ^@ http://purl.uniprot.org/uniprot/A0A8C1M518|||http://purl.uniprot.org/uniprot/A0A8C1Z3B9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC10 family.|||Component of the ER membrane protein complex (EMC).|||Membrane http://togogenome.org/gene/7962:LOC109045202 ^@ http://purl.uniprot.org/uniprot/A0A090BAU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Membrane http://togogenome.org/gene/7962:LOC109055847 ^@ http://purl.uniprot.org/uniprot/A0A8C1JDD9 ^@ Similarity ^@ Belongs to the NUPR family. http://togogenome.org/gene/7962:LOC109068327 ^@ http://purl.uniprot.org/uniprot/A0A8C1C0F1 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/7962:LOC109069406 ^@ http://purl.uniprot.org/uniprot/A0A8C1D5I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:cpb1 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5S7 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/7962:bud31 ^@ http://purl.uniprot.org/uniprot/A0A8C2GGU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/7962:mtnr1aa ^@ http://purl.uniprot.org/uniprot/A0A8C2DBG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.|||Membrane http://togogenome.org/gene/7962:LOC109082163 ^@ http://purl.uniprot.org/uniprot/A0A8C1J617 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109103690 ^@ http://purl.uniprot.org/uniprot/A0A8C1ML96 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109098538 ^@ http://purl.uniprot.org/uniprot/Q90XD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109088299 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q2A7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:LOC109102998 ^@ http://purl.uniprot.org/uniprot/A0A8C1BE18 ^@ Similarity|||Subunit ^@ Belongs to the complex I NDUFC1 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7962:LOC109047331 ^@ http://purl.uniprot.org/uniprot/A0A8C1KK47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CART family.|||Secreted http://togogenome.org/gene/7962:tnfrsf21 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWM7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:fabp3 ^@ http://purl.uniprot.org/uniprot/A0A8C1RYR6 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:aida ^@ http://purl.uniprot.org/uniprot/A0A8C0YJT5 ^@ Similarity ^@ Belongs to the AIDA family. http://togogenome.org/gene/7962:LOC109046443 ^@ http://purl.uniprot.org/uniprot/A0A8C1AB82 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS21 family.|||Component of the 40S small ribosomal subunit.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/7962:LOC109097359 ^@ http://purl.uniprot.org/uniprot/A0A8C1STQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XRCC4-XLF family. XLF subfamily.|||Nucleus http://togogenome.org/gene/7962:nmbb ^@ http://purl.uniprot.org/uniprot/A0A8C1HU46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bombesin/neuromedin-B/ranatensin family.|||Secreted http://togogenome.org/gene/7962:rab11fip4a ^@ http://purl.uniprot.org/uniprot/A0A8C1FWY3 ^@ Subcellular Location Annotation ^@ Cleavage furrow|||Endosome membrane|||Membrane|||Midbody|||Recycling endosome membrane http://togogenome.org/gene/7962:LOC109099711 ^@ http://purl.uniprot.org/uniprot/A0A8C1C8K7 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:LOC109084709 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane http://togogenome.org/gene/7962:polr1e ^@ http://purl.uniprot.org/uniprot/A0A8C1CX65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/7962:aqp11 ^@ http://purl.uniprot.org/uniprot/A0A0K2RVU7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.|||Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109096913 ^@ http://purl.uniprot.org/uniprot/A0A8C1GIB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109050417 ^@ http://purl.uniprot.org/uniprot/A0A8C1C9F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/7962:jagn1b ^@ http://purl.uniprot.org/uniprot/A0A8C1RI14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the jagunal family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:hsd20b2 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCB5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109094339 ^@ http://purl.uniprot.org/uniprot/A0A8C1E6D9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:zgc:113278 ^@ http://purl.uniprot.org/uniprot/A0A8C1LQQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/7962:LOC109102094 ^@ http://purl.uniprot.org/uniprot/A0A8C0YNS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/7962:LOC109089358 ^@ http://purl.uniprot.org/uniprot/A0A8C1B6N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109057999 ^@ http://purl.uniprot.org/uniprot/A0A8C1TAH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109058475 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/7962:LOC109091317 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFG2 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/7962:fabp2 ^@ http://purl.uniprot.org/uniprot/A0A8C2IZW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.|||Cytoplasm http://togogenome.org/gene/7962:ccdc167 ^@ http://purl.uniprot.org/uniprot/A0A8C2GKJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109049193 ^@ http://purl.uniprot.org/uniprot/A0A8C2EFS3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109113238 ^@ http://purl.uniprot.org/uniprot/A0A8C1BZY0 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:actc1b ^@ http://purl.uniprot.org/uniprot/P53479 ^@ Function|||Miscellaneous|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|||Belongs to the actin family.|||In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.|||Methylated at His-75 by SETD3.|||Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.|||Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.|||Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.|||cytoskeleton http://togogenome.org/gene/7962:LOC109091599 ^@ http://purl.uniprot.org/uniprot/A0A8C1WTU5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109047848 ^@ http://purl.uniprot.org/uniprot/A0A8C1JHS0|||http://purl.uniprot.org/uniprot/A0A8C2GS94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS8 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109051622 ^@ http://purl.uniprot.org/uniprot/G7ZL01 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109100837 ^@ http://purl.uniprot.org/uniprot/A0A8C1KL36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. http://togogenome.org/gene/7962:LOC109101580 ^@ http://purl.uniprot.org/uniprot/A0A8C1C9K1 ^@ Similarity ^@ Belongs to the GASK family. http://togogenome.org/gene/7962:aspdh ^@ http://purl.uniprot.org/uniprot/A0A8C1FQM2 ^@ Similarity ^@ Belongs to the L-aspartate dehydrogenase family. http://togogenome.org/gene/7962:LOC109061562 ^@ http://purl.uniprot.org/uniprot/A0A8C0YEE7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:cfap126 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBR6 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the Flattop family. http://togogenome.org/gene/7962:LOC109069326 ^@ http://purl.uniprot.org/uniprot/A0A8C1BW92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:fabp1b.1 ^@ http://purl.uniprot.org/uniprot/A0A8C2EF47 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.|||Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.|||Cytoplasm|||Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. http://togogenome.org/gene/7962:LOC109058438 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZX84 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/7962:LOC109061775 ^@ http://purl.uniprot.org/uniprot/A0A8C1FTC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109085354 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ependymin family.|||Forms disulfide-linked dimers.|||May play a role in neural plasticity. May be involved during axon regeneration.|||Secreted http://togogenome.org/gene/7962:LOC109098121 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5Z2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:tspan34 ^@ http://purl.uniprot.org/uniprot/A0A8C1IVM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109100043 ^@ http://purl.uniprot.org/uniprot/A0A8C1H847 ^@ Similarity ^@ Belongs to the IL-6 superfamily. http://togogenome.org/gene/7962:LOC109065961 ^@ http://purl.uniprot.org/uniprot/A0A8C1D8J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC109065433 ^@ http://purl.uniprot.org/uniprot/A0A8C1GW85 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109077201 ^@ http://purl.uniprot.org/uniprot/A0A8C1PPL3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109102350 ^@ http://purl.uniprot.org/uniprot/A0A8C1BY21|||http://purl.uniprot.org/uniprot/A0A8C1JQF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109099809 ^@ http://purl.uniprot.org/uniprot/A0A8C1DYV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/7962:tmem107l ^@ http://purl.uniprot.org/uniprot/A0A8C1H6T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109060580 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6X4|||http://purl.uniprot.org/uniprot/A0A8C1C9Z6 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109061764 ^@ http://purl.uniprot.org/uniprot/A0A8C1P021 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109084033 ^@ http://purl.uniprot.org/uniprot/A0A8C1KL15 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:ptger4c ^@ http://purl.uniprot.org/uniprot/A0A8C2IG13 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109104974 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZ57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:LOC109048944 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKB3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109097455 ^@ http://purl.uniprot.org/uniprot/A0A8C1VGI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7962:rpl19 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJX7 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Component of the large ribosomal subunit. http://togogenome.org/gene/7962:LOC109102115 ^@ http://purl.uniprot.org/uniprot/A0A8C1L3H1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:gdf6a ^@ http://purl.uniprot.org/uniprot/A0A1S7IX34|||http://purl.uniprot.org/uniprot/A0A8C1FZA1 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109113610 ^@ http://purl.uniprot.org/uniprot/A0A8C1DXP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109056665 ^@ http://purl.uniprot.org/uniprot/A0A8C1C200 ^@ Subcellular Location Annotation ^@ Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109073780 ^@ http://purl.uniprot.org/uniprot/A0A8C1I1T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the jagunal family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:acta2 ^@ http://purl.uniprot.org/uniprot/A0A8C1QQR4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:LOC109069616 ^@ http://purl.uniprot.org/uniprot/A0A8C1C0K4 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:npm2a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3D0 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/7962:LOC109096799 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z053 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the neuromedin-U and neuromedin-S neuropeptides. http://togogenome.org/gene/7962:LOC109096587 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYL6 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/7962:crygm7 ^@ http://purl.uniprot.org/uniprot/A0A8C1E4A0 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109056604 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y9H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109106134 ^@ http://purl.uniprot.org/uniprot/A0A8C1THU9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109074768 ^@ http://purl.uniprot.org/uniprot/A0A8C1IUP9 ^@ Function|||Similarity ^@ Belongs to the MON1/SAND family.|||Plays an important role in membrane trafficking through the secretory apparatus. http://togogenome.org/gene/7962:calcrla ^@ http://purl.uniprot.org/uniprot/A0A8C2KX58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane|||Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. http://togogenome.org/gene/7962:LOC109076977 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZR28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:LOC109086313 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACL5 ^@ Similarity ^@ Belongs to the MARCKS family. http://togogenome.org/gene/7962:LOC109053514 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFJ9 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109068417 ^@ http://purl.uniprot.org/uniprot/A0A8C2FXE3 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/7962:LOC109046808 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZ44 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109078117 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKI9 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:LOC109073324 ^@ http://purl.uniprot.org/uniprot/A0A8C1HVM3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:tcf7l1a ^@ http://purl.uniprot.org/uniprot/A0A8C1D2A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/7962:ap4s1 ^@ http://purl.uniprot.org/uniprot/A0A8C2D3T6 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/7962:LOC109047140 ^@ http://purl.uniprot.org/uniprot/A0A8C1XDV6 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109053904 ^@ http://purl.uniprot.org/uniprot/A0A8C1AW12|||http://purl.uniprot.org/uniprot/A0A8C1K4L2|||http://purl.uniprot.org/uniprot/A0A8C1K8A5|||http://purl.uniprot.org/uniprot/A0A8C1QI87 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/7962:LOC109048024 ^@ http://purl.uniprot.org/uniprot/A0A8C1F1N9 ^@ Similarity ^@ Belongs to the small GTPase superfamily. RGK family. http://togogenome.org/gene/7962:ankrd13d ^@ http://purl.uniprot.org/uniprot/A0A8C1C8E2 ^@ Function|||Subcellular Location Annotation ^@ Endosome|||Late endosome|||Membrane|||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. http://togogenome.org/gene/7962:ca5h11orf54 ^@ http://purl.uniprot.org/uniprot/A0A8C2KZW4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.|||Monomer.|||Nucleus http://togogenome.org/gene/7962:LOC109102136 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan that bears heparan sulfate. http://togogenome.org/gene/7962:LOC109080606 ^@ http://purl.uniprot.org/uniprot/A0A8C1DF91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109056632 ^@ http://purl.uniprot.org/uniprot/A0A8C1AHL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Elbow/Noc family.|||Nucleus http://togogenome.org/gene/7962:LOC109101639 ^@ http://purl.uniprot.org/uniprot/A0A8C1CRH0 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:tmem200a ^@ http://purl.uniprot.org/uniprot/A0A8C1DLD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM200 family.|||Membrane http://togogenome.org/gene/7962:LOC109113342 ^@ http://purl.uniprot.org/uniprot/A0A8C1G306 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109070272 ^@ http://purl.uniprot.org/uniprot/A0A8C1MYT9 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/7962:LOC122133936 ^@ http://purl.uniprot.org/uniprot/A0A8C1C722 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom7 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109093403 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y8C6 ^@ Similarity ^@ Belongs to the PROTOR family. http://togogenome.org/gene/7962:cart2 ^@ http://purl.uniprot.org/uniprot/G7ZL00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CART family.|||Secreted http://togogenome.org/gene/7962:csnk2a2b ^@ http://purl.uniprot.org/uniprot/A0A8C1KLP1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109093090 ^@ http://purl.uniprot.org/uniprot/A0A8C1N5P8 ^@ Similarity ^@ Belongs to the UPF0687 family. http://togogenome.org/gene/7962:LOC109070251 ^@ http://purl.uniprot.org/uniprot/A0A8C1EXZ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109090952 ^@ http://purl.uniprot.org/uniprot/A0A8C2E3D3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/7962:LOC109066726 ^@ http://purl.uniprot.org/uniprot/A0A0K2RVT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109068063 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWV2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:KEF38_p04 ^@ http://purl.uniprot.org/uniprot/Q34046 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:pou3f1 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109111028 ^@ http://purl.uniprot.org/uniprot/A0A8C1KSA4 ^@ Similarity ^@ Belongs to the UPF0561 family. http://togogenome.org/gene/7962:LOC109081220 ^@ http://purl.uniprot.org/uniprot/A0A8C2PLE5 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109113429 ^@ http://purl.uniprot.org/uniprot/A0A8C0YD85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromogranin/secretogranin protein family.|||Secreted http://togogenome.org/gene/7962:LOC109102451 ^@ http://purl.uniprot.org/uniprot/A0A8C1LCM0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109097101 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109045341 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||Tubulin-folding protein; involved in the early step of the tubulin folding pathway.|||cytoskeleton http://togogenome.org/gene/7962:LOC109052870 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIH9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/7962:LOC109085992 ^@ http://purl.uniprot.org/uniprot/A0A8C1H713 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109049589 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ANKH family.|||Membrane|||Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter. http://togogenome.org/gene/7962:LOC109045171 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/7962:LOC109109102 ^@ http://purl.uniprot.org/uniprot/A0A8C0YC77 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109100737 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109073122 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y5Z5 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/7962:gnrh3 ^@ http://purl.uniprot.org/uniprot/Q801D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GnRH family.|||Secreted|||Stimulates the secretion of gonadotropins. http://togogenome.org/gene/7962:LOC109106157 ^@ http://purl.uniprot.org/uniprot/A0A8C0XV87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:pskh1 ^@ http://purl.uniprot.org/uniprot/A0A8C1NF78 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:inha ^@ http://purl.uniprot.org/uniprot/A0A8C1AKX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.|||Secreted http://togogenome.org/gene/7962:rps12 ^@ http://purl.uniprot.org/uniprot/A0A8C2B199 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/7962:opn1sw1 ^@ http://purl.uniprot.org/uniprot/Q7T1Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane|||Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. http://togogenome.org/gene/7962:LOC109062088 ^@ http://purl.uniprot.org/uniprot/A0A8C2IJW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109060302 ^@ http://purl.uniprot.org/uniprot/A0A8C1F751 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/7962:LOC109056803 ^@ http://purl.uniprot.org/uniprot/A0A8C1ESZ0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Component of the signal peptidase complex.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109104072 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2T3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109106796 ^@ http://purl.uniprot.org/uniprot/A0A8C1QTJ8 ^@ Similarity ^@ Belongs to the taxilin family. http://togogenome.org/gene/7962:LOC109069915 ^@ http://purl.uniprot.org/uniprot/A0A8C1CU42 ^@ Similarity ^@ Belongs to the bZIP family. Maf subfamily. http://togogenome.org/gene/7962:LOC109095105 ^@ http://purl.uniprot.org/uniprot/A0A8C1S385 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109104517 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted|||Somatostatin inhibits the release of somatotropin. http://togogenome.org/gene/7962:LOC109097519 ^@ http://purl.uniprot.org/uniprot/A0A8C1AD98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family. GDNF subfamily.|||Homodimer; disulfide-linked.|||Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.|||Secreted http://togogenome.org/gene/7962:LOC109111813 ^@ http://purl.uniprot.org/uniprot/A0A8C1IC79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Engrailed homeobox family.|||Nucleus http://togogenome.org/gene/7962:hexim1 ^@ http://purl.uniprot.org/uniprot/A0A8C1WYY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HEXIM family.|||Nucleus http://togogenome.org/gene/7962:LOC109050629 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KXD1 family.|||Lysosome membrane http://togogenome.org/gene/7962:LOC109097932 ^@ http://purl.uniprot.org/uniprot/A0A8C1E293 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109094644 ^@ http://purl.uniprot.org/uniprot/D2DUP5 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Binds equally well IGF1 and IGF2.|||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109056670 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z0M1 ^@ Function|||Similarity ^@ Belongs to the cytochrome c oxidase subunit 6B.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. http://togogenome.org/gene/7962:LOC109101027 ^@ http://purl.uniprot.org/uniprot/A0A8C1TT42 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.|||Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. http://togogenome.org/gene/7962:LOC109093433 ^@ http://purl.uniprot.org/uniprot/A0A8C1J847 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109056547 ^@ http://purl.uniprot.org/uniprot/A0A8C1AY43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with FEM1A.|||Membrane|||Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. http://togogenome.org/gene/7962:LOC109091362 ^@ http://purl.uniprot.org/uniprot/A0A0M4UPT8 ^@ Similarity ^@ Belongs to the GST superfamily. Alpha family. http://togogenome.org/gene/7962:LOC109079531 ^@ http://purl.uniprot.org/uniprot/A0A8C2AEI2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL7 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109056610 ^@ http://purl.uniprot.org/uniprot/A0A8C1C0E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/7962:LOC109088790 ^@ http://purl.uniprot.org/uniprot/A0A8C1GTU0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/7962:LOC109105725 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAQ2|||http://purl.uniprot.org/uniprot/A0A8C1L4P4 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:si:dkey-71l1.1 ^@ http://purl.uniprot.org/uniprot/A0A8C2H811 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109058980 ^@ http://purl.uniprot.org/uniprot/A0A8C1HJA8 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/7962:LOC109075718 ^@ http://purl.uniprot.org/uniprot/A0A8C1CDK5 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/7962:LOC109078242 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQA7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:LOC109055175 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109056119 ^@ http://purl.uniprot.org/uniprot/A0A8C1PD03 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109047352 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZA8|||http://purl.uniprot.org/uniprot/A0A8C2L1U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109075798 ^@ http://purl.uniprot.org/uniprot/A0A8C0XV47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109049160 ^@ http://purl.uniprot.org/uniprot/A0A8C1FTQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCC3 family.|||Chromosome|||Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.|||Nucleus|||Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.|||centromere http://togogenome.org/gene/7962:LOC109100019 ^@ http://purl.uniprot.org/uniprot/A0A8C2G1N8 ^@ Similarity ^@ Belongs to the PRPH2/ROM1 family. http://togogenome.org/gene/7962:si:dkey-5i3.5 ^@ http://purl.uniprot.org/uniprot/A0A8C1C965 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/7962:LOC109089356 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZ91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109106811 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y781 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109053423 ^@ http://purl.uniprot.org/uniprot/A0A8C2EFS4 ^@ Similarity ^@ Belongs to the ANKRD34 family. http://togogenome.org/gene/7962:gdf2 ^@ http://purl.uniprot.org/uniprot/A0A8C1M490 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:parapinopsinb ^@ http://purl.uniprot.org/uniprot/A0A8C1AYE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109068886 ^@ http://purl.uniprot.org/uniprot/A0A8C1N0C9 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/7962:glrx ^@ http://purl.uniprot.org/uniprot/A0A8C1BAE8 ^@ Function ^@ Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/7962:LOC109082161 ^@ http://purl.uniprot.org/uniprot/A0A8C1P9G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109089337 ^@ http://purl.uniprot.org/uniprot/A0A8C1RTE7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109096045 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZJ7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109100617 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVE7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109046084 ^@ http://purl.uniprot.org/uniprot/A0A8C1B8D6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:pex2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIF0 ^@ Function|||Similarity ^@ Belongs to the pex2/pex10/pex12 family.|||Somewhat implicated in the biogenesis of peroxisomes. http://togogenome.org/gene/7962:LOC109059703 ^@ http://purl.uniprot.org/uniprot/A0A8C1HHF7 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109089141 ^@ http://purl.uniprot.org/uniprot/A0A8C1I722 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTA family.|||Membrane http://togogenome.org/gene/7962:LOC109096904 ^@ http://purl.uniprot.org/uniprot/A0A8C1F812 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109046436 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCJ5 ^@ Similarity ^@ Belongs to the LSM12 family. http://togogenome.org/gene/7962:LOC109102108 ^@ http://purl.uniprot.org/uniprot/A0A8C1L3M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109073665 ^@ http://purl.uniprot.org/uniprot/A0A8C1QBI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:LOC109059491 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP05 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109095042 ^@ http://purl.uniprot.org/uniprot/A0A8C1HIJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:LOC109052854 ^@ http://purl.uniprot.org/uniprot/A0A8C1AHG5 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:LOC109069627 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q5X5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109106058 ^@ http://purl.uniprot.org/uniprot/A0A8C1JHM8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:ehd1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FZV6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109066503 ^@ http://purl.uniprot.org/uniprot/A0A8C1EI95 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:golga5 ^@ http://purl.uniprot.org/uniprot/A0A8C1KBU0 ^@ Function|||Subcellular Location Annotation ^@ Golgi apparatus membrane|||Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.|||Membrane http://togogenome.org/gene/7962:psme3 ^@ http://purl.uniprot.org/uniprot/A0A8C2E696 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/7962:LOC109111922 ^@ http://purl.uniprot.org/uniprot/A0A8C1FCB2|||http://purl.uniprot.org/uniprot/A0A8C1SX59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NSE2 family.|||Nucleus http://togogenome.org/gene/7962:hoxb6b ^@ http://purl.uniprot.org/uniprot/A0A8C2DH92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109109972 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AGK family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109088600 ^@ http://purl.uniprot.org/uniprot/A0A8C1FCG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/7962:LOC109058723 ^@ http://purl.uniprot.org/uniprot/A0A8C1F558 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109063577 ^@ http://purl.uniprot.org/uniprot/A0A8C1JSN1 ^@ Similarity|||Subunit ^@ Belongs to the complex I NDUFC1 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7962:mmp9 ^@ http://purl.uniprot.org/uniprot/A0A8C1TIG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M10A family.|||extracellular matrix http://togogenome.org/gene/7962:LOC109094632 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109068637 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYK3 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109053062 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIY8 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:LOC109066293 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the riboflavin transporter family.|||Cell membrane|||Membrane|||Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. http://togogenome.org/gene/7962:LOC109053699 ^@ http://purl.uniprot.org/uniprot/A0A8C2GB35 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:kdelr2b ^@ http://purl.uniprot.org/uniprot/A0A8C1DLZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109064746 ^@ http://purl.uniprot.org/uniprot/A0A8C1C848 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:wnt3a ^@ http://purl.uniprot.org/uniprot/A0A8C1EBN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109100602 ^@ http://purl.uniprot.org/uniprot/A0A8C1KDE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NUSAP family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109057799 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAV6 ^@ Subcellular Location Annotation ^@ Membrane|||basement membrane http://togogenome.org/gene/7962:LOC109064407 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJV9 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/7962:LOC109071198 ^@ http://purl.uniprot.org/uniprot/A0A8C1KV48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.|||Nucleus http://togogenome.org/gene/7962:LOC109074488 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJH2 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109067319 ^@ http://purl.uniprot.org/uniprot/A0A8C1GWV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109047715 ^@ http://purl.uniprot.org/uniprot/A0A8C1RXL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IFI6/IFI27 family.|||Membrane http://togogenome.org/gene/7962:yif1b ^@ http://purl.uniprot.org/uniprot/A0A8C1HN81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Has a role in transport between endoplasmic reticulum and Golgi.|||Membrane http://togogenome.org/gene/7962:LOC109056193 ^@ http://purl.uniprot.org/uniprot/A0A8C1CED0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109073624 ^@ http://purl.uniprot.org/uniprot/A0A8C2HWG3 ^@ Subcellular Location Annotation ^@ focal adhesion|||lamellipodium|||sarcomere http://togogenome.org/gene/7962:LOC109111604 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 10 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:KEF38_p12 ^@ http://purl.uniprot.org/uniprot/P24972 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 2 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109069675 ^@ http://purl.uniprot.org/uniprot/A0A8C1C4T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GLMP family.|||Lysosome membrane|||Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization. http://togogenome.org/gene/7962:LOC109050007 ^@ http://purl.uniprot.org/uniprot/A0A8C1B965|||http://purl.uniprot.org/uniprot/A0A8C1BBI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Homer family.|||Cytoplasm|||Postsynaptic density|||Synapse http://togogenome.org/gene/7962:actr1b ^@ http://purl.uniprot.org/uniprot/A0A8C2CNJ6 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:LOC109084530 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZH69 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/7962:LOC109086880 ^@ http://purl.uniprot.org/uniprot/A0A8C1F3R8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/7962:LOC109088491 ^@ http://purl.uniprot.org/uniprot/A0A8C1UKI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109103095 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. http://togogenome.org/gene/7962:agpat4 ^@ http://purl.uniprot.org/uniprot/A0A8C1DN09 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/7962:LOC109098431 ^@ http://purl.uniprot.org/uniprot/A0A8C0YRN9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL1 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane|||The C-terminal di-lysine motif may confer endoplasmic reticulum localization. http://togogenome.org/gene/7962:LOC109055749 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109058280 ^@ http://purl.uniprot.org/uniprot/A0A8C1T3A5 ^@ Similarity ^@ Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family. http://togogenome.org/gene/7962:LOC109107853 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:sept9b ^@ http://purl.uniprot.org/uniprot/A0A8C1F2M3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/7962:LOC109103381 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0Q7 ^@ Similarity ^@ Belongs to the apolipoprotein L family. http://togogenome.org/gene/7962:LOC109047129 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109083145 ^@ http://purl.uniprot.org/uniprot/A0A8C1CSB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.|||Membrane http://togogenome.org/gene/7962:sult6b1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C537 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109056071 ^@ http://purl.uniprot.org/uniprot/A0A8C1ETQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC122134057 ^@ http://purl.uniprot.org/uniprot/A0A8C0YPG5 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/7962:LOC109088268 ^@ http://purl.uniprot.org/uniprot/A0A8C1EN17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family. Bicoid subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109075436 ^@ http://purl.uniprot.org/uniprot/A0A8C1F367|||http://purl.uniprot.org/uniprot/A0A8C1F463 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 30 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/7962:LOC109056171 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:nop10 ^@ http://purl.uniprot.org/uniprot/A0A8C2A1P8 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/7962:fabp4b ^@ http://purl.uniprot.org/uniprot/A0A8C1ERI3 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109061368 ^@ http://purl.uniprot.org/uniprot/A0A089ZZW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109089521 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZ59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/7962:slc25a4 ^@ http://purl.uniprot.org/uniprot/A0A8C1HD69 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/7962:LOC109071645 ^@ http://purl.uniprot.org/uniprot/A0A8C1D8H1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109049057 ^@ http://purl.uniprot.org/uniprot/A0A8C1B712 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Endoplasmic reticulum http://togogenome.org/gene/7962:ppp1r14ba ^@ http://purl.uniprot.org/uniprot/A0A8C2K735 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/7962:tbx2a ^@ http://purl.uniprot.org/uniprot/A0A8C1R655 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:mboat7 ^@ http://purl.uniprot.org/uniprot/A0A8C1HVE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109104847 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR65 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:zgc:114188 ^@ http://purl.uniprot.org/uniprot/A0A8C1XPG2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/7962:ndfip1l ^@ http://purl.uniprot.org/uniprot/A0A8C1FKD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109091454 ^@ http://purl.uniprot.org/uniprot/A0A8C1NSD5 ^@ Function ^@ Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. http://togogenome.org/gene/7962:LOC109100003 ^@ http://purl.uniprot.org/uniprot/A0A8C1AP72|||http://purl.uniprot.org/uniprot/A0A8C1G229 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/7962:LOC109101428 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5H9 ^@ Similarity ^@ Belongs to the galactose-3-O-sulfotransferase family. http://togogenome.org/gene/7962:nrn1a ^@ http://purl.uniprot.org/uniprot/A0A8C1BM85 ^@ Similarity ^@ Belongs to the neuritin family. http://togogenome.org/gene/7962:LOC109105105 ^@ http://purl.uniprot.org/uniprot/A0A8C1TR77 ^@ Subcellular Location Annotation ^@ Membrane|||chromaffin granule membrane http://togogenome.org/gene/7962:mrpl52 ^@ http://purl.uniprot.org/uniprot/A0A8C2H977 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL52 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109068246 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:nkx6.3 ^@ http://purl.uniprot.org/uniprot/A0A8C1WBS9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:hscb ^@ http://purl.uniprot.org/uniprot/A0A8C1E3A5 ^@ Similarity ^@ Belongs to the HscB family. http://togogenome.org/gene/7962:LOC109072711 ^@ http://purl.uniprot.org/uniprot/A0A8C1E8I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109082952 ^@ http://purl.uniprot.org/uniprot/A0A8C1URV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/7962:sox12 ^@ http://purl.uniprot.org/uniprot/A0A8C1J9D4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109066534 ^@ http://purl.uniprot.org/uniprot/A0A8C1F226|||http://purl.uniprot.org/uniprot/A0A8C1PVW7 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/7962:sar1ab ^@ http://purl.uniprot.org/uniprot/A0A8C2CP53 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family.|||Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/7962:LOC109097430 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:unkl ^@ http://purl.uniprot.org/uniprot/A0A8C1FB32|||http://purl.uniprot.org/uniprot/A0A8C1FC02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unkempt family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109075956 ^@ http://purl.uniprot.org/uniprot/A0A8C1WLY0 ^@ Function|||Miscellaneous|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.|||Belongs to the MoaD family. MOCS2A subfamily.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.|||Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.|||This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).|||cytosol http://togogenome.org/gene/7962:hoxc9a ^@ http://purl.uniprot.org/uniprot/A0A8C1BYS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109095345 ^@ http://purl.uniprot.org/uniprot/A0A8C1X8H4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.|||cytoskeleton http://togogenome.org/gene/7962:LOC109085541 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109049527 ^@ http://purl.uniprot.org/uniprot/A0A8C1XX08 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:dmrt2b ^@ http://purl.uniprot.org/uniprot/A0A8C0YSD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/7962:LOC109083374 ^@ http://purl.uniprot.org/uniprot/A0A8C1EV94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:dolk ^@ http://purl.uniprot.org/uniprot/A0A8C1EBY0 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/7962:sod1 ^@ http://purl.uniprot.org/uniprot/A0A8C2JGB5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/7962:LOC109103986 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZ78 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/7962:LOC109086055 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKI5 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109070803 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZQ0|||http://purl.uniprot.org/uniprot/A0A8C1D0X0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:cacng1b ^@ http://purl.uniprot.org/uniprot/A0A8C1BES0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.|||Membrane|||Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.|||sarcolemma http://togogenome.org/gene/7962:LOC109111289 ^@ http://purl.uniprot.org/uniprot/A0A8C1CPJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109092279 ^@ http://purl.uniprot.org/uniprot/A0A8C1H929 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. http://togogenome.org/gene/7962:cxcl8a ^@ http://purl.uniprot.org/uniprot/Q1PBV7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:LOC109088556 ^@ http://purl.uniprot.org/uniprot/A0A8C2GQ65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/7962:dnph1 ^@ http://purl.uniprot.org/uniprot/A0A8C2F0Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.|||Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.|||Cytoplasm|||Monomer and homodimer.|||Nucleus http://togogenome.org/gene/7962:LOC109103870 ^@ http://purl.uniprot.org/uniprot/A0A8C1CIY1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/7962:LOC109072173 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZ23 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/7962:LOC109047441 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109074022 ^@ http://purl.uniprot.org/uniprot/A0A8C1MV12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7962:LOC109113735 ^@ http://purl.uniprot.org/uniprot/A0A8C0YL10 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/7962:pick1 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2D4 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.|||cytoskeleton|||perinuclear region|||synaptosome http://togogenome.org/gene/7962:prkra ^@ http://purl.uniprot.org/uniprot/A0A8C1B531 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRKRA family.|||perinuclear region http://togogenome.org/gene/7962:sost ^@ http://purl.uniprot.org/uniprot/A0A8C2E5I5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the sclerostin family.|||Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. http://togogenome.org/gene/7962:LOC109102655 ^@ http://purl.uniprot.org/uniprot/A0A8C1I3Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/7962:LOC109059335 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFU1 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/7962:LOC109106190 ^@ http://purl.uniprot.org/uniprot/A0A8C1IU96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane http://togogenome.org/gene/7962:LOC109063796 ^@ http://purl.uniprot.org/uniprot/A0A8C1E9E4|||http://purl.uniprot.org/uniprot/A0A8C1ECK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM126 family.|||Cell membrane|||Membrane|||cytosol http://togogenome.org/gene/7962:LOC109073519 ^@ http://purl.uniprot.org/uniprot/A0A8C1IMZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:ccnyl1 ^@ http://purl.uniprot.org/uniprot/A0A8C1VH63 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin Y subfamily. http://togogenome.org/gene/7962:LOC109058512 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIX4|||http://purl.uniprot.org/uniprot/A0A8C1I2Y3 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109064312 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRD3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109065659 ^@ http://purl.uniprot.org/uniprot/A0A8C1TEJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:mis18a ^@ http://purl.uniprot.org/uniprot/A0A8C1EPH7 ^@ Function|||Subcellular Location Annotation ^@ Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.|||centromere http://togogenome.org/gene/7962:LOC109112461 ^@ http://purl.uniprot.org/uniprot/A0A8C1P8V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/7962:LOC109062996 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS3 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109061209 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKK1 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/7962:LOC109064582 ^@ http://purl.uniprot.org/uniprot/A0A8C1P5G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TPPP family.|||cytoskeleton http://togogenome.org/gene/7962:ube2g2 ^@ http://purl.uniprot.org/uniprot/A0A8C2CSA8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:ifng1r ^@ http://purl.uniprot.org/uniprot/B6GV48 ^@ Similarity ^@ Belongs to the type II (or gamma) interferon family. http://togogenome.org/gene/7962:notum1a ^@ http://purl.uniprot.org/uniprot/A0A8C0YGA8 ^@ Similarity ^@ Belongs to the pectinacetylesterase family. Notum subfamily. http://togogenome.org/gene/7962:tsen54 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNL7 ^@ Similarity ^@ Belongs to the SEN54 family. http://togogenome.org/gene/7962:kdelr3 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZV41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109068761 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:polr2j ^@ http://purl.uniprot.org/uniprot/A0A8C1N3M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.|||Nucleus http://togogenome.org/gene/7962:LOC109111026 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1X4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109086168 ^@ http://purl.uniprot.org/uniprot/A0A0C6E5A8 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109061905 ^@ http://purl.uniprot.org/uniprot/A0A8C1GXG4 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:LOC109058290 ^@ http://purl.uniprot.org/uniprot/A0A8C2JZF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA60 subfamily.|||Golgi apparatus membrane http://togogenome.org/gene/7962:LOC109074331 ^@ http://purl.uniprot.org/uniprot/A0A8C1P6D2|||http://purl.uniprot.org/uniprot/A0A8C2CNY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. ATF subfamily.|||Nucleus http://togogenome.org/gene/7962:maf1a ^@ http://purl.uniprot.org/uniprot/A0A8C1J7G2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MAF1 family.|||Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.|||Nucleus http://togogenome.org/gene/7962:LOC109077429 ^@ http://purl.uniprot.org/uniprot/A0A8C2DY90 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/7962:hcfc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQK6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109075185 ^@ http://purl.uniprot.org/uniprot/A0A8C1PQR8 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. GMF subfamily. http://togogenome.org/gene/7962:LOC109054122 ^@ http://purl.uniprot.org/uniprot/A0A8C1AQ55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109091510 ^@ http://purl.uniprot.org/uniprot/A0A8C1ITZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7962:snx5 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y774 ^@ Function|||Similarity ^@ Belongs to the sorting nexin family.|||Involved in several stages of intracellular trafficking. http://togogenome.org/gene/7962:LOC109058451 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZXM2 ^@ Similarity ^@ Belongs to the apolipoprotein A1/A4/E family. http://togogenome.org/gene/7962:LOC109075983 ^@ http://purl.uniprot.org/uniprot/A0A8C1ULD9 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/7962:elf3 ^@ http://purl.uniprot.org/uniprot/A0A8C1AH43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109063262 ^@ http://purl.uniprot.org/uniprot/A0A8C1MA61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109110571 ^@ http://purl.uniprot.org/uniprot/A0A8C1BT83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:cript ^@ http://purl.uniprot.org/uniprot/A0A8C0Y611 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRIPT family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109107180 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5D1 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/7962:mea1 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3Q3 ^@ Function ^@ May play an important role in spermatogenesis and/or testis development. http://togogenome.org/gene/7962:LOC109082343 ^@ http://purl.uniprot.org/uniprot/A0A8C1UJS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109111065 ^@ http://purl.uniprot.org/uniprot/A0A8C1RT44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus|||telomere http://togogenome.org/gene/7962:anxa13l ^@ http://purl.uniprot.org/uniprot/A0A8C1SUY3 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/7962:LOC109094663 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJ74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:LOC109061815 ^@ http://purl.uniprot.org/uniprot/A0A8C1JCJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPY family.|||Secreted http://togogenome.org/gene/7962:ppardb ^@ http://purl.uniprot.org/uniprot/A0A8C1U173 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109098954 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y9U8 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/7962:itgb3b ^@ http://purl.uniprot.org/uniprot/A0A8C1FLL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Membrane http://togogenome.org/gene/7962:LOC109090903 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked.|||Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales. http://togogenome.org/gene/7962:LOC109107955 ^@ http://purl.uniprot.org/uniprot/A0A8C1H513 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/7962:LOC109100612 ^@ http://purl.uniprot.org/uniprot/A0A8C1BMW2 ^@ Caution|||Similarity ^@ Belongs to the fibulin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109071464 ^@ http://purl.uniprot.org/uniprot/A0A8C1C561 ^@ Similarity ^@ Belongs to the Arg-specific ADP-ribosyltransferase family. http://togogenome.org/gene/7962:LOC109053404 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5X3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:pclaf ^@ http://purl.uniprot.org/uniprot/A0A8C1EPI4 ^@ Subcellular Location Annotation ^@ Nucleus|||perinuclear region http://togogenome.org/gene/7962:LOC109076299 ^@ http://purl.uniprot.org/uniprot/A0A8C2EHV1 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109092366 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109074156 ^@ http://purl.uniprot.org/uniprot/A0A8C1DSU7 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:onecut3b ^@ http://purl.uniprot.org/uniprot/A0A8C1CXC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/7962:cfap299 ^@ http://purl.uniprot.org/uniprot/A0A8C1WN33 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in spermatogenesis.|||Nucleus http://togogenome.org/gene/7962:LOC109059818 ^@ http://purl.uniprot.org/uniprot/A0A8C1MRN1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109066277 ^@ http://purl.uniprot.org/uniprot/A0A8C1X2R8 ^@ Similarity ^@ Belongs to the UPF0461 family. http://togogenome.org/gene/7962:LOC109080440 ^@ http://purl.uniprot.org/uniprot/A0A8C1EEH4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109111998 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6G7 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/7962:LOC109110704 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQA7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/7962:nat15 ^@ http://purl.uniprot.org/uniprot/A0A8C0YEK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA60 subfamily.|||Golgi apparatus membrane http://togogenome.org/gene/7962:LOC109046691 ^@ http://purl.uniprot.org/uniprot/A0A8C1H438 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Golgi apparatus membrane http://togogenome.org/gene/7962:LOC109084368 ^@ http://purl.uniprot.org/uniprot/A0A8C1EU77 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/7962:LOC109056261 ^@ http://purl.uniprot.org/uniprot/M9T2B5 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:mul1a ^@ http://purl.uniprot.org/uniprot/A0A8C2A422 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:ripply2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ripply family.|||Nucleus http://togogenome.org/gene/7962:LOC109073019 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:igf1 ^@ http://purl.uniprot.org/uniprot/Q90325 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted|||The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. http://togogenome.org/gene/7962:LOC109108913 ^@ http://purl.uniprot.org/uniprot/A0A8C1WHJ6 ^@ Similarity ^@ Belongs to the dapper family. http://togogenome.org/gene/7962:LOC109056927 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVI7 ^@ Similarity ^@ Belongs to the Arg-specific ADP-ribosyltransferase family. http://togogenome.org/gene/7962:lzic ^@ http://purl.uniprot.org/uniprot/A0A8C1ZNQ8 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/7962:LOC109100188 ^@ http://purl.uniprot.org/uniprot/A0A8C2AZF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109108967 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANY1 ^@ Similarity ^@ Belongs to the isthmin family. http://togogenome.org/gene/7962:orai1a ^@ http://purl.uniprot.org/uniprot/A0A8C1GDS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/7962:tmem41ab ^@ http://purl.uniprot.org/uniprot/A0A8C2I968 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/7962:sigmar1 ^@ http://purl.uniprot.org/uniprot/A0A8C1KAN6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ERG2 family.|||Cytoplasmic vesicle|||Endoplasmic reticulum membrane|||Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.|||Homotrimer.|||Membrane|||Nucleus envelope|||Nucleus inner membrane|||Nucleus outer membrane|||The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.|||Vesicle http://togogenome.org/gene/7962:mdh1ab ^@ http://purl.uniprot.org/uniprot/A0A8C1HHR7 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/7962:marveld1 ^@ http://purl.uniprot.org/uniprot/A0A8C1RYJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109087698 ^@ http://purl.uniprot.org/uniprot/A0A8C1I1P5 ^@ Similarity ^@ Belongs to the PHYHIP family. http://togogenome.org/gene/7962:sstr3 ^@ http://purl.uniprot.org/uniprot/A0A8C2FGM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109105991 ^@ http://purl.uniprot.org/uniprot/A0A8C1JUN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Bcl-2 family.|||Membrane http://togogenome.org/gene/7962:LOC109087341 ^@ http://purl.uniprot.org/uniprot/A0A8C1NAF9 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/7962:chst14 ^@ http://purl.uniprot.org/uniprot/A0A8C1FAA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:drd7 ^@ http://purl.uniprot.org/uniprot/A0A8C1BDJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:psmd12 ^@ http://purl.uniprot.org/uniprot/A0A8C1NCU1 ^@ Similarity ^@ Belongs to the proteasome subunit p55 family. http://togogenome.org/gene/7962:LOC109053827 ^@ http://purl.uniprot.org/uniprot/A0A8C1W5V9 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/7962:LOC109111639 ^@ http://purl.uniprot.org/uniprot/A0A8C2BZ51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS5 subunit family.|||Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109067829 ^@ http://purl.uniprot.org/uniprot/A0A8C1E658 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109113165 ^@ http://purl.uniprot.org/uniprot/A0A8C1AR51 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:LOC109100076 ^@ http://purl.uniprot.org/uniprot/A0A8C2BWG5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/7962:gjc4b ^@ http://purl.uniprot.org/uniprot/A0A8C1C6I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:tardbpa ^@ http://purl.uniprot.org/uniprot/A0A8C1E3S2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109058321 ^@ http://purl.uniprot.org/uniprot/A0A8C1HMQ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109058726 ^@ http://purl.uniprot.org/uniprot/A0A8C2J928 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:LOC109059821 ^@ http://purl.uniprot.org/uniprot/A0A8C1QKB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109048126 ^@ http://purl.uniprot.org/uniprot/A0A8C1VGE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/7962:LOC109052696 ^@ http://purl.uniprot.org/uniprot/A0A8C2A883 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/7962:LOC109091735 ^@ http://purl.uniprot.org/uniprot/A0A8C1H1M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INKA family.|||Nucleus http://togogenome.org/gene/7962:LOC109086069 ^@ http://purl.uniprot.org/uniprot/A0A8C2ASJ6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/7962:LOC109083150 ^@ http://purl.uniprot.org/uniprot/A0A8C1HYK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAS family.|||focal adhesion http://togogenome.org/gene/7962:LOC109081721 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109088362 ^@ http://purl.uniprot.org/uniprot/A0A8C1IBM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109047830 ^@ http://purl.uniprot.org/uniprot/A0A8C0YPD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/7962:LOC109062217 ^@ http://purl.uniprot.org/uniprot/A0A8C1BZQ8 ^@ Function|||Subcellular Location Annotation ^@ Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.|||Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.|||Secreted http://togogenome.org/gene/7962:LOC109050103 ^@ http://purl.uniprot.org/uniprot/A0A8C1RSM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:igfbp5a ^@ http://purl.uniprot.org/uniprot/A0A8C2A3X8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109048101 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUY5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:parietopsin ^@ http://purl.uniprot.org/uniprot/A0A8C1VGX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109099472 ^@ http://purl.uniprot.org/uniprot/A0A8C1RWR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORM family.|||Endoplasmic reticulum membrane|||Membrane|||Negative regulator of sphingolipid synthesis. http://togogenome.org/gene/7962:LOC109099968 ^@ http://purl.uniprot.org/uniprot/A0A8C1P3V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDNFR family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109113682 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRINL1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109058382 ^@ http://purl.uniprot.org/uniprot/A0A8C1GB92 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109091697 ^@ http://purl.uniprot.org/uniprot/A0A8C1CCK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109111062 ^@ http://purl.uniprot.org/uniprot/A0A8C1AA45 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109105923 ^@ http://purl.uniprot.org/uniprot/A0A8C1KDE3 ^@ Similarity ^@ Belongs to the HINT family. http://togogenome.org/gene/7962:LOC109054264 ^@ http://purl.uniprot.org/uniprot/A0A8C1M6D5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109063216 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVU0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:arl3b ^@ http://purl.uniprot.org/uniprot/A0A8C1F7N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7962:LOC109102078 ^@ http://purl.uniprot.org/uniprot/A0A8C1BY57 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109110174 ^@ http://purl.uniprot.org/uniprot/A0A8C1IP49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the C19orf12 family.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109063257 ^@ http://purl.uniprot.org/uniprot/A0A8C1CP18 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/7962:LOC109088907 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJL9 ^@ Similarity ^@ Belongs to the CARF family. http://togogenome.org/gene/7962:LOC109048966 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABT2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109077373 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 16 (GT16) protein family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109096476 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBV3 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:fundc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:pam16 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZB2 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/7962:kcnj10a ^@ http://purl.uniprot.org/uniprot/A0A8C1DLH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109058839 ^@ http://purl.uniprot.org/uniprot/A0A8C1KY48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/7962:LOC109049209 ^@ http://purl.uniprot.org/uniprot/A0A8C2B7N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:LOC109081871 ^@ http://purl.uniprot.org/uniprot/A0A8C1W6Y8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109094578 ^@ http://purl.uniprot.org/uniprot/A0A8C2D0U4 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7962:LOC109050562 ^@ http://purl.uniprot.org/uniprot/A0A8C1UB66 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/7962:LOC109096686 ^@ http://purl.uniprot.org/uniprot/A0A8C1SAJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KRTCAP2 family.|||Membrane http://togogenome.org/gene/7962:vps25 ^@ http://purl.uniprot.org/uniprot/A0A8C2AA14 ^@ Similarity ^@ Belongs to the VPS25 family. http://togogenome.org/gene/7962:LOC109061876 ^@ http://purl.uniprot.org/uniprot/A0A8C1CK44 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109096922 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1T5 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109061918 ^@ http://purl.uniprot.org/uniprot/A0A8C1DA31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109094685 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 30 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/7962:LOC109110250 ^@ http://purl.uniprot.org/uniprot/A0A8C1HVX1 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/7962:cckar ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109100145 ^@ http://purl.uniprot.org/uniprot/A0A8C1GGX4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:wnt6a ^@ http://purl.uniprot.org/uniprot/A0A8C1R1Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:otx1 ^@ http://purl.uniprot.org/uniprot/A0A8C1X9U4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109067812 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Lipocalin family.|||Secreted http://togogenome.org/gene/7962:LOC109080575 ^@ http://purl.uniprot.org/uniprot/A0A8C1JC43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:ppa2 ^@ http://purl.uniprot.org/uniprot/A0A8C1HLV8 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/7962:ubac2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109070186 ^@ http://purl.uniprot.org/uniprot/A0A8C2DDG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NKAIN family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109051923 ^@ http://purl.uniprot.org/uniprot/A0A8C2A7V8 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109061213 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.|||cytoskeleton http://togogenome.org/gene/7962:LOC109063330 ^@ http://purl.uniprot.org/uniprot/A0A8C1T6B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BLOC1S1 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109102104 ^@ http://purl.uniprot.org/uniprot/A0A8C2PUD4 ^@ Similarity ^@ Belongs to the synuclein family. http://togogenome.org/gene/7962:LOC109057654 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZM19 ^@ Similarity ^@ Belongs to the UPF0390 family. http://togogenome.org/gene/7962:LOC109046681 ^@ http://purl.uniprot.org/uniprot/A0A8C1EFN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PET117 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109094047 ^@ http://purl.uniprot.org/uniprot/A0A8C1NF21 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7962:LOC109049412 ^@ http://purl.uniprot.org/uniprot/A0A8C1AIX5 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/7962:LOC109092500 ^@ http://purl.uniprot.org/uniprot/A0A8C2BK20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasmic vesicle|||G-protein coupled receptor for 5-hydroxytryptamine (serotonin).|||Membrane|||Presynapse|||Synapse|||Vesicle|||axon|||caveola|||dendrite http://togogenome.org/gene/7962:LOC109083419 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVD2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:lsm1 ^@ http://purl.uniprot.org/uniprot/A0A8C1PRL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/7962:LOC109110207 ^@ http://purl.uniprot.org/uniprot/A0A8C1UR84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCB family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109081382 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQR4|||http://purl.uniprot.org/uniprot/A0A8C1HX85 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:eif4ebp2 ^@ http://purl.uniprot.org/uniprot/A0A8C1D660 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/7962:LOC109054171 ^@ http://purl.uniprot.org/uniprot/A0A8C2G5Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/7962:b3galt6 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:spam1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLK6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/7962:LOC109092957 ^@ http://purl.uniprot.org/uniprot/A0A8C1SD81 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:fam53b ^@ http://purl.uniprot.org/uniprot/A0A8C1TDH3 ^@ Similarity ^@ Belongs to the FAM53 family. http://togogenome.org/gene/7962:LOC109067146 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the orexin family.|||Cytoplasmic vesicle|||Endoplasmic reticulum|||Synapse|||Vesicle http://togogenome.org/gene/7962:LOC109064388 ^@ http://purl.uniprot.org/uniprot/A0A8C1ED20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/7962:LOC109065627 ^@ http://purl.uniprot.org/uniprot/A0A8C1DAS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/7962:LOC109094144 ^@ http://purl.uniprot.org/uniprot/A0A8C2HGF1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/7962:LOC109092153 ^@ http://purl.uniprot.org/uniprot/A0A8C1H1J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109096674 ^@ http://purl.uniprot.org/uniprot/A0A8C1QE12 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109076027 ^@ http://purl.uniprot.org/uniprot/A0A8C1F3S8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:znf830 ^@ http://purl.uniprot.org/uniprot/A0A8C1CGU0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109099029 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the INSIG family.|||Endoplasmic reticulum membrane|||Mediates feedback control of cholesterol synthesis.|||Membrane http://togogenome.org/gene/7962:LOC109076183 ^@ http://purl.uniprot.org/uniprot/A0A8C1IVL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109072795 ^@ http://purl.uniprot.org/uniprot/A0A8C1C5F4 ^@ Function|||Similarity ^@ Belongs to the intermediate filament family.|||Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. http://togogenome.org/gene/7962:cflara ^@ http://purl.uniprot.org/uniprot/A0A8C1C4G7 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:lpcat4 ^@ http://purl.uniprot.org/uniprot/A0A8C1CPD2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/7962:tmed10 ^@ http://purl.uniprot.org/uniprot/A0A8C2BTE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:letmd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1MMJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109085342 ^@ http://purl.uniprot.org/uniprot/A0A8C1C9K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions and the hemichannels.|||gap junction http://togogenome.org/gene/7962:LOC109054996 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABK9 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7962:LOC109104815 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:mpeg1.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1P314 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPEG1 family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/7962:LOC109103310 ^@ http://purl.uniprot.org/uniprot/A0A8C1PR18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/7962:LOC109047662 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPSF4/YTH1 family.|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex.|||Nucleus http://togogenome.org/gene/7962:LOC109048197 ^@ http://purl.uniprot.org/uniprot/A0A8C1ET69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:slc25a33 ^@ http://purl.uniprot.org/uniprot/A0A8C2DKI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:pde5aa ^@ http://purl.uniprot.org/uniprot/A0A8C1HVG0 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109069346 ^@ http://purl.uniprot.org/uniprot/A0A8C1D546 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109066137 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/7962:LOC109104946 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:lyplal1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AK05 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. http://togogenome.org/gene/7962:LOC109092677 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the APH-1 family.|||Component of the gamma-secretase complex.|||Membrane|||Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors. http://togogenome.org/gene/7962:LOC109050767 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJN4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109047783 ^@ http://purl.uniprot.org/uniprot/A0A8C1LMZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109045726 ^@ http://purl.uniprot.org/uniprot/A0A8C1NKJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7962:LOC109046075 ^@ http://purl.uniprot.org/uniprot/A0A8C1YC46 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:med6 ^@ http://purl.uniprot.org/uniprot/A0A8C1N5V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109105813 ^@ http://purl.uniprot.org/uniprot/A0A8C1JJR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109053968 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1V6 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/7962:LOC109100551 ^@ http://purl.uniprot.org/uniprot/A0A8C1PQ24 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109075799 ^@ http://purl.uniprot.org/uniprot/A0A8C1DF99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm http://togogenome.org/gene/7962:gpn2 ^@ http://purl.uniprot.org/uniprot/A0A8C1UFG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/7962:LOC109098860 ^@ http://purl.uniprot.org/uniprot/A0A8C1IG05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bestrophin family.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/7962:LOC109064905 ^@ http://purl.uniprot.org/uniprot/A0A8C1JX38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109100773 ^@ http://purl.uniprot.org/uniprot/A0A8C1RJK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR3 family.|||Endosome membrane|||Late endosome membrane http://togogenome.org/gene/7962:slc25a48 ^@ http://purl.uniprot.org/uniprot/A0A8C1M4D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:pofut1 ^@ http://purl.uniprot.org/uniprot/A0A8C1D089 ^@ Similarity ^@ Belongs to the glycosyltransferase 65 family. http://togogenome.org/gene/7962:LOC109098096 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:nipa1 ^@ http://purl.uniprot.org/uniprot/A0A8C2BML2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/7962:med11 ^@ http://purl.uniprot.org/uniprot/A0A8C1GTR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 11 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:best4 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bestrophin family.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/7962:LOC109060158 ^@ http://purl.uniprot.org/uniprot/A0A8C1GQ24 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:oprd1b ^@ http://purl.uniprot.org/uniprot/A0A8C1K6X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109098102 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109058414 ^@ http://purl.uniprot.org/uniprot/A0A8C2BUW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:ppa1b ^@ http://purl.uniprot.org/uniprot/A0A8C2CMQ5 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/7962:LOC109056753 ^@ http://purl.uniprot.org/uniprot/A0A8C2DPU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with BRAWNIN.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109049498 ^@ http://purl.uniprot.org/uniprot/A0A8C1D4M8 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:ndufb6 ^@ http://purl.uniprot.org/uniprot/A0A8C2IZN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB6 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109061572 ^@ http://purl.uniprot.org/uniprot/A0A8C1E975 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR0 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109107973 ^@ http://purl.uniprot.org/uniprot/A0A8C1YZ49 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||gap junction http://togogenome.org/gene/7962:cdo1 ^@ http://purl.uniprot.org/uniprot/Q2PFL2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit.|||Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen. http://togogenome.org/gene/7962:LOC109110761 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZQQ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109101566 ^@ http://purl.uniprot.org/uniprot/A0A8C1YNE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/7962:LOC109062375 ^@ http://purl.uniprot.org/uniprot/A0A8C2JAS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.|||Membrane|||Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109082219 ^@ http://purl.uniprot.org/uniprot/A0A8C2EW30 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/7962:tram2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YA70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/7962:LOC109091615 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109084194 ^@ http://purl.uniprot.org/uniprot/A0A8C1L422 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109051034 ^@ http://purl.uniprot.org/uniprot/A0A8C1B1E0|||http://purl.uniprot.org/uniprot/A0A8C1H612 ^@ Function|||Similarity ^@ Belongs to the RNase H family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. http://togogenome.org/gene/7962:LOC109099612 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNU5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/7962:LOC109060877 ^@ http://purl.uniprot.org/uniprot/A0A8C1B949 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:insm1b ^@ http://purl.uniprot.org/uniprot/A0A8C1L4D2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:dpm2 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y223 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Membrane|||Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. http://togogenome.org/gene/7962:LOC109066258 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1C4 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:LOC109100699 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5D2|||http://purl.uniprot.org/uniprot/A0A8C1Q2S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/7962:LOC109045185 ^@ http://purl.uniprot.org/uniprot/A0A8C1HB27 ^@ Subunit ^@ Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity. http://togogenome.org/gene/7962:LOC109048845 ^@ http://purl.uniprot.org/uniprot/A0A8C0YHZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cell surface|||Endosome|||Membrane http://togogenome.org/gene/7962:LOC109085599 ^@ http://purl.uniprot.org/uniprot/A0A8C1XFX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109103170 ^@ http://purl.uniprot.org/uniprot/A0A8C1QPR7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sft2d3 ^@ http://purl.uniprot.org/uniprot/A0A8C1X3B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:LOC109083096 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAM9 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/7962:LOC109112176 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1L6 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/7962:LOC109104704 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2P4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109105745 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:phf5a ^@ http://purl.uniprot.org/uniprot/A0A8C2EXZ6 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/7962:mrap2b ^@ http://purl.uniprot.org/uniprot/A0A8C1NTJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MRAP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109083149 ^@ http://purl.uniprot.org/uniprot/A0A8C1FA59 ^@ Similarity ^@ Belongs to the GORASP family. http://togogenome.org/gene/7962:LOC109092739 ^@ http://purl.uniprot.org/uniprot/A0A8C1BIV7 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/7962:LOC109050538 ^@ http://purl.uniprot.org/uniprot/A0A8C2C3K7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109104631 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q805 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexin family.|||Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/7962:gcnt4a ^@ http://purl.uniprot.org/uniprot/A0A8C1X497 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109085593 ^@ http://purl.uniprot.org/uniprot/A0A8C2KK94 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109056773 ^@ http://purl.uniprot.org/uniprot/A0A8C1DUH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109069334 ^@ http://purl.uniprot.org/uniprot/A0A8C1BZ90|||http://purl.uniprot.org/uniprot/A0A8C1ZJG6 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/7962:LOC109100984 ^@ http://purl.uniprot.org/uniprot/A0A8C1MVU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:arpc5b ^@ http://purl.uniprot.org/uniprot/A0A8C1V373 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/7962:LOC109088851 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/7962:LOC109102309 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQ38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NGF-beta family.|||Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.|||Secreted http://togogenome.org/gene/7962:LOC109086662 ^@ http://purl.uniprot.org/uniprot/A0A8C2JHN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom5 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:opn6b ^@ http://purl.uniprot.org/uniprot/A0A8C1B8T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109084013 ^@ http://purl.uniprot.org/uniprot/A0A8C1DW77 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109069488 ^@ http://purl.uniprot.org/uniprot/A0A8C1K626 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109063321 ^@ http://purl.uniprot.org/uniprot/A0A8C1QVC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BLOC1S1 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109061663 ^@ http://purl.uniprot.org/uniprot/A0A8C1PTL3 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily. http://togogenome.org/gene/7962:LOC109098937 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y609 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:apex2 ^@ http://purl.uniprot.org/uniprot/A0A8C1I4L1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Cytoplasm|||Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.|||Mitochondrion|||Nucleus|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/7962:slc25a32a ^@ http://purl.uniprot.org/uniprot/A0A8C1F4M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:pigv ^@ http://purl.uniprot.org/uniprot/A0A8C1K692 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGV family.|||Endoplasmic reticulum membrane|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.|||Membrane http://togogenome.org/gene/7962:LOC109088766 ^@ http://purl.uniprot.org/uniprot/A0A8C1EAB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109097431 ^@ http://purl.uniprot.org/uniprot/A0A8C1YI90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVBP family.|||Secreted|||cytoskeleton http://togogenome.org/gene/7962:LOC109111796 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bZIP family.|||Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.|||Binds to the cAMP response element and activates transcription.|||Nucleus http://togogenome.org/gene/7962:LOC109058577 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPV7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109090655 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/7962:LOC109103179 ^@ http://purl.uniprot.org/uniprot/A0A8C1L1H2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:LOC109113566 ^@ http://purl.uniprot.org/uniprot/A0A8C2K3L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 7B2 family.|||Secreted http://togogenome.org/gene/7962:zgc:103482 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACT8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109109906 ^@ http://purl.uniprot.org/uniprot/A0A8C1AIQ6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109055771 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109049234 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actinoporin family. Sea anemone subfamily.|||Cell membrane|||Membrane|||Nematocyst|||Target cell membrane http://togogenome.org/gene/7962:LOC109063472 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane http://togogenome.org/gene/7962:LOC109066058 ^@ http://purl.uniprot.org/uniprot/A0A8C1CDZ4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/7962:LOC109047814 ^@ http://purl.uniprot.org/uniprot/A0A8C1EC32|||http://purl.uniprot.org/uniprot/A0A8C1EEF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109068514 ^@ http://purl.uniprot.org/uniprot/A0A8C1CH93 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109095934 ^@ http://purl.uniprot.org/uniprot/A0A8C1ARK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109096078 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTB4 ^@ Similarity ^@ Belongs to the protein phosphatase inhibitor 1 family. http://togogenome.org/gene/7962:LOC109082000 ^@ http://purl.uniprot.org/uniprot/A0A8C1N9E0 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109079454 ^@ http://purl.uniprot.org/uniprot/A0A8C1V890 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sept3 ^@ http://purl.uniprot.org/uniprot/A0A8C1ECH1 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/7962:LOC109090890 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:lyrm9 ^@ http://purl.uniprot.org/uniprot/A0A8C1A265 ^@ Similarity ^@ Belongs to the complex I LYR family. LYRM9 subfamily. http://togogenome.org/gene/7962:LOC109075790 ^@ http://purl.uniprot.org/uniprot/A0A8C1M4J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STARD3 family.|||Endosome membrane|||Late endosome membrane|||Membrane http://togogenome.org/gene/7962:tm4sf4 ^@ http://purl.uniprot.org/uniprot/A0A8C2PMX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/7962:LOC109097326 ^@ http://purl.uniprot.org/uniprot/A0A8C2JAW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS11 family.|||Cytoplasmic vesicle|||Early endosome|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.|||autophagosome|||clathrin-coated vesicle http://togogenome.org/gene/7962:LOC109090386 ^@ http://purl.uniprot.org/uniprot/A0A8C1A1S5 ^@ Subcellular Location Annotation ^@ Membrane|||cytoskeleton http://togogenome.org/gene/7962:rap2c ^@ http://purl.uniprot.org/uniprot/A0A8C2F0E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ras family.|||Endosome membrane|||Recycling endosome membrane http://togogenome.org/gene/7962:tm2d3 ^@ http://purl.uniprot.org/uniprot/A0A8C1AC80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109102290 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQH2 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109049716 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWK4 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109049535 ^@ http://purl.uniprot.org/uniprot/A0A8C1B393 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109071128 ^@ http://purl.uniprot.org/uniprot/A0A8C2BYA0 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109065262 ^@ http://purl.uniprot.org/uniprot/A0A8C1ELC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the vestigial family.|||Nucleus http://togogenome.org/gene/7962:lhx5 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8J6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109075623 ^@ http://purl.uniprot.org/uniprot/A0A0M4UG63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/7962:LOC109082033 ^@ http://purl.uniprot.org/uniprot/A0A8C1FP52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.|||Forms a homohexamer that can probably bind six kinase subunits. http://togogenome.org/gene/7962:gadd45ab ^@ http://purl.uniprot.org/uniprot/A0A8C1NRW2 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109068395 ^@ http://purl.uniprot.org/uniprot/A0A8C1C387 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/7962:LOC109111483 ^@ http://purl.uniprot.org/uniprot/A0A8C1RP61 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/7962:LOC109103763 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:ufd1l ^@ http://purl.uniprot.org/uniprot/A0A8C1ZXP1 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/7962:LOC109065232 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEZ2 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/7962:LOC109105577 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/7962:dennd6aa ^@ http://purl.uniprot.org/uniprot/A0A8C1HQ48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DENND6 family.|||Endosome|||Recycling endosome http://togogenome.org/gene/7962:LOC109084262 ^@ http://purl.uniprot.org/uniprot/A0A8C1DVL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GST superfamily.|||Membrane http://togogenome.org/gene/7962:myoz2b ^@ http://purl.uniprot.org/uniprot/A0A8C1MHE2 ^@ Similarity ^@ Belongs to the myozenin family. http://togogenome.org/gene/7962:LOC109064607 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZV95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:trak1a ^@ http://purl.uniprot.org/uniprot/A0A8C1CTC7|||http://purl.uniprot.org/uniprot/A0A8C1CTY7|||http://purl.uniprot.org/uniprot/A0A8C1CV59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the milton family.|||Early endosome|||Mitochondrion http://togogenome.org/gene/7962:ifrd2 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q8N0|||http://purl.uniprot.org/uniprot/A0A8C2Q8Y3 ^@ Similarity ^@ Belongs to the IFRD family. http://togogenome.org/gene/7962:dynlrb1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HBB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109085915 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKP2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. http://togogenome.org/gene/7962:LOC109050560 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGV family.|||Endoplasmic reticulum membrane|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.|||Membrane http://togogenome.org/gene/7962:LOC109090455 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3U8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/7962:LOC109058714 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2U1 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:LOC109055706 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVK4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109109889 ^@ http://purl.uniprot.org/uniprot/A0A8C1LYT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 6A family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109097308 ^@ http://purl.uniprot.org/uniprot/A0A8C1KXB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM134/TMEM230 family.|||Early endosome|||Endosome|||Involved in trafficking and recycling of synaptic vesicles.|||Late endosome|||Membrane|||Recycling endosome|||Vesicle|||autophagosome|||synaptic vesicle|||trans-Golgi network http://togogenome.org/gene/7962:LOC109051949 ^@ http://purl.uniprot.org/uniprot/A0A8C1I8D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109112762 ^@ http://purl.uniprot.org/uniprot/A0A8C1QI08 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/7962:dkk1a ^@ http://purl.uniprot.org/uniprot/A0A8C1W4Y7 ^@ Similarity ^@ Belongs to the dickkopf family. http://togogenome.org/gene/7962:mnx1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVI8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109104188 ^@ http://purl.uniprot.org/uniprot/A0A8C2ALW4 ^@ Similarity ^@ Belongs to the LAMTOR4 family. http://togogenome.org/gene/7962:LOC109109190 ^@ http://purl.uniprot.org/uniprot/A0A8C1MAI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM256 family.|||Membrane http://togogenome.org/gene/7962:ercc1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YBY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/7962:si:dkey-150i13.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:ca8h9orf64 ^@ http://purl.uniprot.org/uniprot/A0A8C2BXU6 ^@ Function|||Similarity ^@ Belongs to the queuosine salvage protein family.|||Involved in salvaging queuosine. http://togogenome.org/gene/7962:LOC109060427 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8S1 ^@ Function|||Subcellular Location Annotation ^@ Golgi apparatus membrane|||May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. http://togogenome.org/gene/7962:LOC109055462 ^@ http://purl.uniprot.org/uniprot/A0A8C1B312 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7962:LOC109101665 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109093900 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQD0 ^@ Similarity ^@ Belongs to the MINAR family. http://togogenome.org/gene/7962:LOC109096678 ^@ http://purl.uniprot.org/uniprot/A0A8C1KI19 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:fam162a ^@ http://purl.uniprot.org/uniprot/A0A8C1RN90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/7962:LOC109059817 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/7962:LOC109092353 ^@ http://purl.uniprot.org/uniprot/A0A8C2HVT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BAMBI family.|||Membrane|||Negatively regulates TGF-beta signaling. http://togogenome.org/gene/7962:lpar4 ^@ http://purl.uniprot.org/uniprot/A0A8C1MP34 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:chmp2a ^@ http://purl.uniprot.org/uniprot/A0A8C1CJ67 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:akt2 ^@ http://purl.uniprot.org/uniprot/A0A8C2JVX9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. http://togogenome.org/gene/7962:LOC109051507 ^@ http://purl.uniprot.org/uniprot/A0A8C2KDH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0669 family.|||Secreted http://togogenome.org/gene/7962:LOC109054915 ^@ http://purl.uniprot.org/uniprot/A0A8C1CDU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the C19orf12 family.|||Mitochondrion membrane http://togogenome.org/gene/7962:yipf4 ^@ http://purl.uniprot.org/uniprot/A0A8C1CW96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/7962:LOC109104599 ^@ http://purl.uniprot.org/uniprot/A0A8C1CTH9 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.|||May play a role in motor coordination and exploratory behavior. http://togogenome.org/gene/7962:LOC109081731 ^@ http://purl.uniprot.org/uniprot/A0A8C1FBC0 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/7962:LOC109073099 ^@ http://purl.uniprot.org/uniprot/A0A8C1F0Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MUSTANG family.|||Nucleus http://togogenome.org/gene/7962:si:dkey-234i14.3 ^@ http://purl.uniprot.org/uniprot/A0A8C1EX28 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109095575 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPEG1 family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/7962:LOC109105586 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109069306 ^@ http://purl.uniprot.org/uniprot/A0A8C1HE06 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:lhfpl6 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109078276 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the junctophilin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109100278 ^@ http://purl.uniprot.org/uniprot/Q8UUS3 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:st6galnac1.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CW23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/7962:mrps18a ^@ http://purl.uniprot.org/uniprot/A0A8C2B8D3 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/7962:LOC109111631 ^@ http://purl.uniprot.org/uniprot/A0A8C1AP73 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:nmur1a ^@ http://purl.uniprot.org/uniprot/A0A8C1EWT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the neuromedin-U and neuromedin-S neuropeptides. http://togogenome.org/gene/7962:LOC109069361 ^@ http://purl.uniprot.org/uniprot/A0A8C1JYK0 ^@ Similarity ^@ Belongs to the dermatopontin family. http://togogenome.org/gene/7962:tbx21 ^@ http://purl.uniprot.org/uniprot/A0A8C1CRP8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:kdelr2a ^@ http://purl.uniprot.org/uniprot/A0A8C1RSN2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109106105 ^@ http://purl.uniprot.org/uniprot/A0A8C2AXQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:ak6 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZD7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.|||Cajal body|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. Interacts with COIL (via C-terminus).|||nucleoplasm http://togogenome.org/gene/7962:LOC109059395 ^@ http://purl.uniprot.org/uniprot/A0A8C1QWV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.|||cytoskeleton http://togogenome.org/gene/7962:LOC109060377 ^@ http://purl.uniprot.org/uniprot/A0A8C1EA74 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109056958 ^@ http://purl.uniprot.org/uniprot/A0A8C1HC77 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109045332 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the synembryn family.|||Cytoplasm|||Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.|||Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma. http://togogenome.org/gene/7962:entpd8 ^@ http://purl.uniprot.org/uniprot/A0A8C1B1S9 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/7962:LOC109104593 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA35 ^@ Similarity ^@ Belongs to the GORAB family. http://togogenome.org/gene/7962:LOC109090729 ^@ http://purl.uniprot.org/uniprot/A0A8C2QAQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/7962:LOC109107886 ^@ http://purl.uniprot.org/uniprot/A0A8C1KLD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:hcar1-3 ^@ http://purl.uniprot.org/uniprot/A0A8C2AY64 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109066913 ^@ http://purl.uniprot.org/uniprot/A0A8C1D5V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Mitochondrion|||Nucleus|||centrosome|||spindle http://togogenome.org/gene/7962:LOC109075899 ^@ http://purl.uniprot.org/uniprot/A0A8C1INX8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MoaE family. MOCS2B subfamily.|||Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.|||Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.|||This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).|||cytosol http://togogenome.org/gene/7962:LOC109078714 ^@ http://purl.uniprot.org/uniprot/A0A8C1D7A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109098508 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ODAM family.|||Cytoplasm|||Interacts (via C-terminus) with ARHGEF5.|||Nucleus|||Secreted|||Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface. http://togogenome.org/gene/7962:sike1 ^@ http://purl.uniprot.org/uniprot/A0A8C1VFG0 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/7962:szl ^@ http://purl.uniprot.org/uniprot/A0A2Z5YR38 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109057651 ^@ http://purl.uniprot.org/uniprot/A0A8C1C5I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109105006 ^@ http://purl.uniprot.org/uniprot/A0A8C1ASS5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P2X receptor family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Receptor for ATP that acts as a ligand-gated ion channel. http://togogenome.org/gene/7962:LOC109111823 ^@ http://purl.uniprot.org/uniprot/A0A8C2L8E2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:LOC109090485 ^@ http://purl.uniprot.org/uniprot/A0A8C1K544 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GST superfamily. Pi family.|||Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.|||Cytoplasm|||Homodimer.|||Mitochondrion|||Nucleus http://togogenome.org/gene/7962:ssbp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CY11|||http://purl.uniprot.org/uniprot/A0A8C1D0C2 ^@ Subcellular Location Annotation ^@ mitochondrion nucleoid http://togogenome.org/gene/7962:ubl3b ^@ http://purl.uniprot.org/uniprot/A0A8C1AUC2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:adipor1b ^@ http://purl.uniprot.org/uniprot/A0A8C1H1Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109062288 ^@ http://purl.uniprot.org/uniprot/A0A8C2AAV2 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase family.|||Homodimer. http://togogenome.org/gene/7962:LOC109056155 ^@ http://purl.uniprot.org/uniprot/A0A8C1SDS5 ^@ Similarity ^@ Belongs to the TRIM/RBCC family. http://togogenome.org/gene/7962:LOC109065517 ^@ http://purl.uniprot.org/uniprot/A0A8C1ARE9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:mtx3 ^@ http://purl.uniprot.org/uniprot/A0A8C2G4C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metaxin family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109047784 ^@ http://purl.uniprot.org/uniprot/A0A8C1IDE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109109161 ^@ http://purl.uniprot.org/uniprot/A0A8C1JCT7 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/7962:LOC109050120 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCN1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109105889 ^@ http://purl.uniprot.org/uniprot/A0A8C2C5D1 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:olfml2a ^@ http://purl.uniprot.org/uniprot/A0A8C1BQ74 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:cdk2ap2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FT63 ^@ Similarity ^@ Belongs to the CDK2AP family. http://togogenome.org/gene/7962:LOC109054588 ^@ http://purl.uniprot.org/uniprot/A0A8C1BP69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LST8 family.|||Cytoplasm|||Part of TORC1 complex. Part of the TORC2 complex.|||Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. http://togogenome.org/gene/7962:grk4 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2X1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/7962:igfbp2a ^@ http://purl.uniprot.org/uniprot/C3TTM8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109088132 ^@ http://purl.uniprot.org/uniprot/A0A8C1BAT6 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:cldn15a ^@ http://purl.uniprot.org/uniprot/A0A8C1PVY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:endouc ^@ http://purl.uniprot.org/uniprot/A0A8C1X8R2 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/7962:LOC109064106 ^@ http://purl.uniprot.org/uniprot/A0A8C1EX18 ^@ Similarity ^@ Belongs to the RIB43A family. http://togogenome.org/gene/7962:LOC109099517 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:cnih2 ^@ http://purl.uniprot.org/uniprot/A0A8C1X7D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/7962:LOC109050617 ^@ http://purl.uniprot.org/uniprot/A0A8C1AM72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. http://togogenome.org/gene/7962:LOC109102745 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109091809 ^@ http://purl.uniprot.org/uniprot/A0A8C2BK14 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109096057 ^@ http://purl.uniprot.org/uniprot/A0A8C1BA87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ATPase subunit F6 family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109083323 ^@ http://purl.uniprot.org/uniprot/A0A8C1N3K3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:ca7h16orf87 ^@ http://purl.uniprot.org/uniprot/A0A8C1EYM4 ^@ Similarity ^@ Belongs to the UPF0547 family. http://togogenome.org/gene/7962:LOC109053209 ^@ http://purl.uniprot.org/uniprot/A0A8C1M9I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gastrin/cholecystokinin family.|||Secreted http://togogenome.org/gene/7962:LOC109090287 ^@ http://purl.uniprot.org/uniprot/A0A8C2IFW7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:zdhhc22 ^@ http://purl.uniprot.org/uniprot/A0A8C1FWT6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109055785 ^@ http://purl.uniprot.org/uniprot/A0A8C2DK55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/7962:fgf21 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHX9 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109049047 ^@ http://purl.uniprot.org/uniprot/A0A8C2IC94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). http://togogenome.org/gene/7962:LOC109109097 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIS9 ^@ Subcellular Location Annotation ^@ Apical cell membrane|||Cell membrane|||Lipid droplet http://togogenome.org/gene/7962:tmtops3a ^@ http://purl.uniprot.org/uniprot/A0A8C1MCR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:slc7a6os ^@ http://purl.uniprot.org/uniprot/A0A8C1A5R4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IWR1/SLC7A6OS family.|||Cytoplasm|||Directs RNA polymerase II nuclear import.|||Nucleus http://togogenome.org/gene/7962:LOC109051345 ^@ http://purl.uniprot.org/uniprot/A0A8C1QZK5 ^@ Function|||Similarity ^@ Belongs to the calcitonin family.|||Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. http://togogenome.org/gene/7962:LOC109093431 ^@ http://purl.uniprot.org/uniprot/A0A8C1JA92 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109073672 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasmic vesicle membrane http://togogenome.org/gene/7962:LOC109086878 ^@ http://purl.uniprot.org/uniprot/A0A8C1F445 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109086563 ^@ http://purl.uniprot.org/uniprot/A0A8C2HDF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:npvf ^@ http://purl.uniprot.org/uniprot/A0A8C0YHU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FARP (FMRFamide related peptide) family.|||Secreted http://togogenome.org/gene/7962:LOC109079579 ^@ http://purl.uniprot.org/uniprot/A0A8C1DT26 ^@ Similarity ^@ Belongs to the G-alpha family. G(s) subfamily. http://togogenome.org/gene/7962:cmbl ^@ http://purl.uniprot.org/uniprot/A0A8C1U1I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dienelactone hydrolase family.|||cytosol http://togogenome.org/gene/7962:LOC109074520 ^@ http://purl.uniprot.org/uniprot/A0A8C1FCL5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109046558 ^@ http://purl.uniprot.org/uniprot/A0A8C1CPY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts specifically as a negative regulator of skeletal muscle growth.|||Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Secreted http://togogenome.org/gene/7962:gys2 ^@ http://purl.uniprot.org/uniprot/A0A8C2FG52 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 3 family.|||Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. http://togogenome.org/gene/7962:ppp6c ^@ http://purl.uniprot.org/uniprot/A0A8C1B8P3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7962:LOC109088904 ^@ http://purl.uniprot.org/uniprot/A0A8C1HY95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/7962:LOC109048667 ^@ http://purl.uniprot.org/uniprot/A0A1S7IX00 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109091597 ^@ http://purl.uniprot.org/uniprot/A0A8C2JMY8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/7962:LOC109113504 ^@ http://purl.uniprot.org/uniprot/A0A8C0YFD1 ^@ Caution|||Function|||Subunit ^@ Interacts with ITGAL, ITGAM and ITGB2.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. http://togogenome.org/gene/7962:LOC109084246 ^@ http://purl.uniprot.org/uniprot/A0A8C1IFC6 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109113340 ^@ http://purl.uniprot.org/uniprot/A0A8C1BGE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109070197 ^@ http://purl.uniprot.org/uniprot/A0A8C1QZN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/7962:LOC109053825 ^@ http://purl.uniprot.org/uniprot/A0A8C1M7H5 ^@ Similarity ^@ Belongs to the Arg-specific ADP-ribosyltransferase family. http://togogenome.org/gene/7962:bcl2l1 ^@ http://purl.uniprot.org/uniprot/A0A8C1JXA4 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/7962:LOC109056799 ^@ http://purl.uniprot.org/uniprot/A0A8C2ACA1 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109058620 ^@ http://purl.uniprot.org/uniprot/A0A8C1PRI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109103785 ^@ http://purl.uniprot.org/uniprot/A0A8C2CW58 ^@ Function ^@ Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. http://togogenome.org/gene/7962:LOC109071168 ^@ http://purl.uniprot.org/uniprot/A0A8C1AYU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:cacfd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EY96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane http://togogenome.org/gene/7962:LOC109055142 ^@ http://purl.uniprot.org/uniprot/A0A8C1DAL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-2-microglobulin family.|||Secreted http://togogenome.org/gene/7962:LOC109070191 ^@ http://purl.uniprot.org/uniprot/A0A8C1FP45 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:pyya ^@ http://purl.uniprot.org/uniprot/A0A8C1NLT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPY family.|||Secreted http://togogenome.org/gene/7962:cdc42ep3 ^@ http://purl.uniprot.org/uniprot/A0A8C2CIV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109105049 ^@ http://purl.uniprot.org/uniprot/A0A8C1A293 ^@ Subcellular Location Annotation ^@ PML body|||autophagosome|||cytosol http://togogenome.org/gene/7962:KEF38_p05 ^@ http://purl.uniprot.org/uniprot/P67784|||http://purl.uniprot.org/uniprot/Q14F85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4L family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109069964 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6Y1|||http://purl.uniprot.org/uniprot/A0A8C1HKX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109113522 ^@ http://purl.uniprot.org/uniprot/A0A8C1M3M8|||http://purl.uniprot.org/uniprot/A0A8C1M6I6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109107387 ^@ http://purl.uniprot.org/uniprot/A0A8C1E599 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109087850 ^@ http://purl.uniprot.org/uniprot/A0A8C1N571 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109110894 ^@ http://purl.uniprot.org/uniprot/A0A8C1JJ20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/7962:LOC109098580 ^@ http://purl.uniprot.org/uniprot/A0A8C1GLS6 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/7962:LOC109077670 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZ58 ^@ Similarity ^@ Belongs to the learning-associated protein family. http://togogenome.org/gene/7962:LOC109074786 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIX0 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109103401 ^@ http://purl.uniprot.org/uniprot/A0A8C1B408 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEN-2 family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/7962:LOC109105685 ^@ http://purl.uniprot.org/uniprot/A0A8C1BET5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Lysosome http://togogenome.org/gene/7962:npy1r ^@ http://purl.uniprot.org/uniprot/A0A8C1HAU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109104860 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQE9 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109095406 ^@ http://purl.uniprot.org/uniprot/A0A1V0ELI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Su(H) family.|||Nucleus http://togogenome.org/gene/7962:LOC109054643 ^@ http://purl.uniprot.org/uniprot/A0A8C1HB22 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:zfp36l2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BRE5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:LOC109106771 ^@ http://purl.uniprot.org/uniprot/A0A8C1U968 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/7962:scocb ^@ http://purl.uniprot.org/uniprot/A0A8C1J630 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/7962:LOC109103424 ^@ http://purl.uniprot.org/uniprot/A0A8C1WAZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPSB family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109100600 ^@ http://purl.uniprot.org/uniprot/A0A8C2PVG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM39 family.|||Membrane http://togogenome.org/gene/7962:zgc:101744 ^@ http://purl.uniprot.org/uniprot/A0A8C1RCE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/7962:LOC109053144 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEB9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:polr1d ^@ http://purl.uniprot.org/uniprot/A0A8C1HA77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/7962:LOC109065435 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM88 family.|||Membrane http://togogenome.org/gene/7962:rgs7bpb ^@ http://purl.uniprot.org/uniprot/A0A8C0YFA8 ^@ Similarity ^@ Belongs to the RGS7BP/RGS9BP family. http://togogenome.org/gene/7962:tmed7 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7962:hapln1a ^@ http://purl.uniprot.org/uniprot/A0A8C1WXG2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:sult1st5 ^@ http://purl.uniprot.org/uniprot/A0A8C1S9L3 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109050124 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3V5|||http://purl.uniprot.org/uniprot/A0A8C2Q453 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/7962:tmem144a ^@ http://purl.uniprot.org/uniprot/A0A8C1BST9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM144 family.|||Membrane http://togogenome.org/gene/7962:LOC109106457 ^@ http://purl.uniprot.org/uniprot/A0A8C1PAT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:foxg1c ^@ http://purl.uniprot.org/uniprot/A0A8C1HEY8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109065283 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NGF-beta family.|||Secreted|||Seems to promote the survival of visceral and proprioceptive sensory neurons. http://togogenome.org/gene/7962:LOC109094626 ^@ http://purl.uniprot.org/uniprot/A0A8C1D5N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/7962:LOC109068852 ^@ http://purl.uniprot.org/uniprot/A0A8C1CDX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109101394 ^@ http://purl.uniprot.org/uniprot/A0A8C1H2B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCR4/nocturin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109069658 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7962:LOC109061854 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSP0 ^@ Function|||Similarity ^@ Belongs to the DDAH family.|||Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. http://togogenome.org/gene/7962:zgc:101559 ^@ http://purl.uniprot.org/uniprot/A0A8C1FY60 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/7962:tpm4a ^@ http://purl.uniprot.org/uniprot/A0A8C0YH02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109096958 ^@ http://purl.uniprot.org/uniprot/A0A8C2CD39 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:LOC109055589 ^@ http://purl.uniprot.org/uniprot/A0A8C1QVF4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109064527 ^@ http://purl.uniprot.org/uniprot/A0A8C1FRA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7962:LOC109049154 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane|||Secreted http://togogenome.org/gene/7962:themis ^@ http://purl.uniprot.org/uniprot/A0A8C1C226 ^@ Similarity ^@ Belongs to the themis family. http://togogenome.org/gene/7962:LOC109058567 ^@ http://purl.uniprot.org/uniprot/A0A8C1CIT2 ^@ Similarity ^@ Belongs to the Arg-specific ADP-ribosyltransferase family. http://togogenome.org/gene/7962:LOC109077936 ^@ http://purl.uniprot.org/uniprot/A0A8C1ES03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109087391 ^@ http://purl.uniprot.org/uniprot/A0A8C1RKY7 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109094613 ^@ http://purl.uniprot.org/uniprot/A0A8C2L825 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR5 family.|||Lysosome http://togogenome.org/gene/7962:LOC109070136 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGI0 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:sdf4 ^@ http://purl.uniprot.org/uniprot/A0A8C1IA75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREC family.|||Golgi apparatus lumen http://togogenome.org/gene/7962:LOC109093441 ^@ http://purl.uniprot.org/uniprot/A0A8C1SJ43 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/7962:LOC109101706 ^@ http://purl.uniprot.org/uniprot/A0A8C1J8B5 ^@ Similarity ^@ Belongs to the SLAIN motif-containing family. http://togogenome.org/gene/7962:LOC109098535 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPC7 ^@ Function|||Similarity ^@ Belongs to the type IB topoisomerase family.|||Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/7962:LOC109050077 ^@ http://purl.uniprot.org/uniprot/A0A8C1N615 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:apcs ^@ http://purl.uniprot.org/uniprot/A0A8C1B4N1 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pentraxin family.|||Binds 2 calcium ions per subunit.|||Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109092485 ^@ http://purl.uniprot.org/uniprot/A0A8C1ED06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109061823 ^@ http://purl.uniprot.org/uniprot/A0A8C1WBB1 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:LOC109078947 ^@ http://purl.uniprot.org/uniprot/A0A8C1JFW5 ^@ Subcellular Location Annotation ^@ Z line http://togogenome.org/gene/7962:oip5 ^@ http://purl.uniprot.org/uniprot/A0A8C1H669 ^@ Function|||Subcellular Location Annotation ^@ Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.|||centromere http://togogenome.org/gene/7962:LOC109063357 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109096573 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZI8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/7962:LOC109059202 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109074258 ^@ http://purl.uniprot.org/uniprot/A0A8C1IRG2 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/7962:inka2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INKA family.|||Nucleus http://togogenome.org/gene/7962:LOC109054129 ^@ http://purl.uniprot.org/uniprot/A0A8C1X1R4 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/7962:LOC109051776 ^@ http://purl.uniprot.org/uniprot/A0A8C1LG04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109068182 ^@ http://purl.uniprot.org/uniprot/A0A8C2DNV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/7962:si:dkey-21c1.4 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANT6 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/7962:LOC109071866 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBU5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109080085 ^@ http://purl.uniprot.org/uniprot/A0A8C1QIN5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109073119 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109109704 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:rnasekb ^@ http://purl.uniprot.org/uniprot/A0A8C2G7L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/7962:LOC109092122 ^@ http://purl.uniprot.org/uniprot/A0A8C1J589 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/7962:LOC109059515 ^@ http://purl.uniprot.org/uniprot/A0A8C1EE36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:thg1l ^@ http://purl.uniprot.org/uniprot/A0A8C1C8W4 ^@ Cofactor|||Function|||Similarity ^@ Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.|||Belongs to the tRNA(His) guanylyltransferase family.|||Binds 2 magnesium ions per subunit. http://togogenome.org/gene/7962:LOC109065967 ^@ http://purl.uniprot.org/uniprot/A0A8C1XIK9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/7962:inhbb ^@ http://purl.uniprot.org/uniprot/A0A8C1BFK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.|||Secreted http://togogenome.org/gene/7962:cacng1a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y640 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.|||Membrane|||Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.|||sarcolemma http://togogenome.org/gene/7962:LOC109107116 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQT2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109107754 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109081153 ^@ http://purl.uniprot.org/uniprot/A0A8C1K401 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted|||VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. http://togogenome.org/gene/7962:dbr1 ^@ http://purl.uniprot.org/uniprot/A0A8C1D333 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lariat debranching enzyme family.|||Nucleus http://togogenome.org/gene/7962:LOC109045221 ^@ http://purl.uniprot.org/uniprot/A0A8C1PQB8 ^@ Function ^@ Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/7962:nrp2b ^@ http://purl.uniprot.org/uniprot/A0A8C1AR82 ^@ Caution|||Similarity ^@ Belongs to the neuropilin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109102081 ^@ http://purl.uniprot.org/uniprot/A0A8C1BX36 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109102186 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRF2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109100970 ^@ http://purl.uniprot.org/uniprot/A0A8C2JX03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic mitochondrial porin family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109093044 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZ04 ^@ Function|||Similarity ^@ Belongs to the non-lysosomal glucosylceramidase family.|||Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. http://togogenome.org/gene/7962:ndufb11 ^@ http://purl.uniprot.org/uniprot/A0A8C1AM43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB11 subunit family.|||Membrane http://togogenome.org/gene/7962:LOC109062016 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKH8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/7962:ndufaf4 ^@ http://purl.uniprot.org/uniprot/A0A8C1B799 ^@ Similarity|||Subunit ^@ Belongs to the NDUFAF4 family.|||Binds calmodulin. Interacts with NDUFAF3. http://togogenome.org/gene/7962:LOC109105203 ^@ http://purl.uniprot.org/uniprot/A0A8C2F0Y6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109060132 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tissue factor family.|||Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.|||Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII. http://togogenome.org/gene/7962:mpdu1a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109062859 ^@ http://purl.uniprot.org/uniprot/A0A8C2HW25 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Binds equally well IGF1 and IGF2.|||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109094193 ^@ http://purl.uniprot.org/uniprot/A0A8C1AQS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dpy-19 family.|||Membrane|||Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. http://togogenome.org/gene/7962:LOC109073843 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQ22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type I cytokine receptor family. Type 4 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109101637 ^@ http://purl.uniprot.org/uniprot/A0A8C1BIN3 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/7962:ptx3a ^@ http://purl.uniprot.org/uniprot/A0A8C1QCN2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109049959 ^@ http://purl.uniprot.org/uniprot/A0A8C1S803 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:psma1 ^@ http://purl.uniprot.org/uniprot/A0A8C1MJB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/7962:LOC109103238 ^@ http://purl.uniprot.org/uniprot/A0A8C1HHN6 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/7962:cmc1 ^@ http://purl.uniprot.org/uniprot/A0A8C1RL43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109103800 ^@ http://purl.uniprot.org/uniprot/A0A8C1RDL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109062934 ^@ http://purl.uniprot.org/uniprot/A0A8C1HSU2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109084844 ^@ http://purl.uniprot.org/uniprot/A0A8C1DYZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the opioid neuropeptide precursor family.|||Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.|||Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.|||Leumorphin has a typical opiod activity and may have anti-apoptotic effect.|||Secreted http://togogenome.org/gene/7962:LOC109049004 ^@ http://purl.uniprot.org/uniprot/A0A8C1DVP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109049107 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAX1 ^@ Similarity ^@ Belongs to the paralemmin family. http://togogenome.org/gene/7962:LOC109111584 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109045199 ^@ http://purl.uniprot.org/uniprot/A0A8C2AJG0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109057399 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVE8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/7962:LOC109060009 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBL6 ^@ Similarity ^@ Belongs to the MHC class I family. http://togogenome.org/gene/7962:LOC109100633 ^@ http://purl.uniprot.org/uniprot/A0A8C1NM76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OLFML3 family.|||Secreted http://togogenome.org/gene/7962:LOC109047987 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7S4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/7962:zic6 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:hoxa1a ^@ http://purl.uniprot.org/uniprot/A0A8C1K0I2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109055782 ^@ http://purl.uniprot.org/uniprot/A0A8C1ALT8 ^@ Similarity ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family. http://togogenome.org/gene/7962:LOC109080650 ^@ http://purl.uniprot.org/uniprot/A0A8C1MAR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109062911 ^@ http://purl.uniprot.org/uniprot/A0A8C1U197 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/7962:nkx2.2b ^@ http://purl.uniprot.org/uniprot/A0A8C1AR66 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109100173 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109110358 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3W5 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/7962:hspb9 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6X1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:mrpl18 ^@ http://purl.uniprot.org/uniprot/A0A8C1AV58 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/7962:LOC109091481 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Cell projection|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||cytoskeleton http://togogenome.org/gene/7962:LOC109059162 ^@ http://purl.uniprot.org/uniprot/A0A8C1FUE0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.|||Membrane|||Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. http://togogenome.org/gene/7962:LOC109090948 ^@ http://purl.uniprot.org/uniprot/A0A8C2JRG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||COPI-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109066663 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109076610 ^@ http://purl.uniprot.org/uniprot/A0A8C1XL30 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:LOC109063360 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109066636 ^@ http://purl.uniprot.org/uniprot/A0A8C1QLY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7962:rpl4 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIG1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL4 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/7962:btf3 ^@ http://purl.uniprot.org/uniprot/A0A8C0YUW1 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/7962:LOC109082764 ^@ http://purl.uniprot.org/uniprot/A0A8C1QY65 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.|||Belongs to the p53 family.|||Binds 1 zinc ion per subunit.|||Binds DNA as a homotetramer.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109108686 ^@ http://purl.uniprot.org/uniprot/A0A8C1DM35|||http://purl.uniprot.org/uniprot/A0A8C1DPX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/7962:LOC109086961 ^@ http://purl.uniprot.org/uniprot/A0A8C1VDF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109047768 ^@ http://purl.uniprot.org/uniprot/A0A8C1GXH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/7962:cks2 ^@ http://purl.uniprot.org/uniprot/A0A8C1JZI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.|||Forms a homohexamer that can probably bind six kinase subunits. http://togogenome.org/gene/7962:LOC109064240 ^@ http://purl.uniprot.org/uniprot/A0A8C2PQJ8 ^@ Similarity ^@ Belongs to the LanC-like protein family. http://togogenome.org/gene/7962:rab9a ^@ http://purl.uniprot.org/uniprot/A0A8C1S3Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||phagosome membrane http://togogenome.org/gene/7962:nek8 ^@ http://purl.uniprot.org/uniprot/A0A8C1DH26 ^@ Similarity ^@ Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. http://togogenome.org/gene/7962:LOC109094729 ^@ http://purl.uniprot.org/uniprot/A0A8C2C0N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:sephs1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFM6 ^@ Function ^@ Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/7962:LOC109062479 ^@ http://purl.uniprot.org/uniprot/A0A8C1E3H7 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/7962:LOC109113359 ^@ http://purl.uniprot.org/uniprot/A0A8C1BXA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7962:LOC109060731 ^@ http://purl.uniprot.org/uniprot/A0A8C1QCA6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:seh1l ^@ http://purl.uniprot.org/uniprot/A0A8C1AF24|||http://purl.uniprot.org/uniprot/A0A8C1H1C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC13 family.|||Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.|||Lysosome membrane|||kinetochore http://togogenome.org/gene/7962:LOC109111484 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5Y3 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109093936 ^@ http://purl.uniprot.org/uniprot/A0A8C1PHQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the myelin proteolipid protein family.|||Membrane http://togogenome.org/gene/7962:LOC109101012 ^@ http://purl.uniprot.org/uniprot/A0A089ZWW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||May act as a zinc-influx transporter.|||Membrane http://togogenome.org/gene/7962:LOC109047354 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZD5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109103762 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109076694 ^@ http://purl.uniprot.org/uniprot/A0A8C1S8D5 ^@ Similarity|||Subunit ^@ Belongs to the GILT family.|||Dimer; disulfide-linked. http://togogenome.org/gene/7962:LOC109103423 ^@ http://purl.uniprot.org/uniprot/A0A8C2FX26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109081384 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX90 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:fgfr1b ^@ http://purl.uniprot.org/uniprot/A0A8C1HXY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:zgc:158260 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNW6 ^@ Similarity ^@ Belongs to the FAM47 family. http://togogenome.org/gene/7962:bscl2l ^@ http://purl.uniprot.org/uniprot/A0A8C1HP24 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:ppp1r14aa ^@ http://purl.uniprot.org/uniprot/A0A8C1UCK1 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/7962:LOC109049066 ^@ http://purl.uniprot.org/uniprot/A0A8C1H736 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109049065 ^@ http://purl.uniprot.org/uniprot/A0A8C1B6Y5|||http://purl.uniprot.org/uniprot/A0A8C1B941 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062432 ^@ http://purl.uniprot.org/uniprot/A0A8C1STL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/7962:LOC109076049 ^@ http://purl.uniprot.org/uniprot/A0A8C1F601 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109048200 ^@ http://purl.uniprot.org/uniprot/A0A8C1HXJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109082956 ^@ http://purl.uniprot.org/uniprot/A0A8C1HNE1 ^@ Function|||Similarity ^@ Belongs to the MEIG1 family.|||Essential for spermiogenesis. http://togogenome.org/gene/7962:LOC109069700 ^@ http://purl.uniprot.org/uniprot/A0A8C2FCK3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:btd ^@ http://purl.uniprot.org/uniprot/A0A8C1EQ03 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/7962:LOC109055450 ^@ http://purl.uniprot.org/uniprot/A0A8C1FV06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109063003 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:lim2.4 ^@ http://purl.uniprot.org/uniprot/A0A8C2HJ32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/7962:LOC109062387 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQM9 ^@ Similarity ^@ Belongs to the peptidase M24 family. http://togogenome.org/gene/7962:LOC109074386 ^@ http://purl.uniprot.org/uniprot/A0A8C1QHH4 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the PA-phosphatase related phosphoesterase family.|||Cell membrane|||Membrane|||Membrane raft|||caveola http://togogenome.org/gene/7962:LOC109063573 ^@ http://purl.uniprot.org/uniprot/A0A8C1N1N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:tmem216 ^@ http://purl.uniprot.org/uniprot/A0A8C0YJI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109069123 ^@ http://purl.uniprot.org/uniprot/A0A8C1EXI3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:LOC109108120 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFH6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:si:dkey-110g7.8 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5W6|||http://purl.uniprot.org/uniprot/A0A8C1MR56 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109059017 ^@ http://purl.uniprot.org/uniprot/A0A8C1XVW3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/7962:klhl15 ^@ http://purl.uniprot.org/uniprot/A0A8C1EXI4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:vps72b ^@ http://purl.uniprot.org/uniprot/A0A8C2KKP6 ^@ Function|||Similarity ^@ Belongs to the VPS72/YL1 family.|||Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. http://togogenome.org/gene/7962:arl6ip5a ^@ http://purl.uniprot.org/uniprot/A0A8C1C3G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7962:LOC109092391 ^@ http://purl.uniprot.org/uniprot/A0A8C1EEU3 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/7962:LOC109059751 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP43|||http://purl.uniprot.org/uniprot/A0A8C1R844 ^@ Similarity ^@ Belongs to the TOM1 family. http://togogenome.org/gene/7962:LOC109085372 ^@ http://purl.uniprot.org/uniprot/A0A8C1F3U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.|||Cytoplasm|||Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.|||Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. http://togogenome.org/gene/7962:LOC109105968 ^@ http://purl.uniprot.org/uniprot/A0A8C1RMC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:si:ch211-225p5.8 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC122134060 ^@ http://purl.uniprot.org/uniprot/A0A8C1C450|||http://purl.uniprot.org/uniprot/A0A8C1LU36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Homer family.|||Cytoplasm|||Postsynaptic density|||Synapse http://togogenome.org/gene/7962:LOC109098751 ^@ http://purl.uniprot.org/uniprot/A0A8C0YGC5 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/7962:slc10a3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.|||Membrane http://togogenome.org/gene/7962:LOC109087090 ^@ http://purl.uniprot.org/uniprot/A0A0M4TQ82 ^@ Similarity ^@ Belongs to the GST superfamily. Mu family. http://togogenome.org/gene/7962:spcs3 ^@ http://purl.uniprot.org/uniprot/A0A8C1LUG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109098042 ^@ http://purl.uniprot.org/uniprot/A0A8C1GLI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM218 family.|||May be involved in ciliary biogenesis or function.|||Membrane|||cilium http://togogenome.org/gene/7962:or40a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1VF77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109094139 ^@ http://purl.uniprot.org/uniprot/A0A8C1IIT1 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/7962:LOC109076521 ^@ http://purl.uniprot.org/uniprot/A0A8C1RYC3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/7962:LOC109049941 ^@ http://purl.uniprot.org/uniprot/A0A8C1NXN9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109056845 ^@ http://purl.uniprot.org/uniprot/A0A8C1H7Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/7962:LOC109092277 ^@ http://purl.uniprot.org/uniprot/A0A8C2A5U2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:leap2 ^@ http://purl.uniprot.org/uniprot/R4JN37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LEAP2 family.|||Has an antimicrobial activity.|||Secreted http://togogenome.org/gene/7962:LOC109105488 ^@ http://purl.uniprot.org/uniprot/A0A8C1HDL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha/beta interferon family.|||Secreted http://togogenome.org/gene/7962:LOC109073523 ^@ http://purl.uniprot.org/uniprot/A0A8C1AAN0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/7962:LOC109108883 ^@ http://purl.uniprot.org/uniprot/A0A8C1MEF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:LOC109056482 ^@ http://purl.uniprot.org/uniprot/A0A8C1FR90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109083146 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7U2|||http://purl.uniprot.org/uniprot/A0A8C1VNC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109106817 ^@ http://purl.uniprot.org/uniprot/A0A8C1A9A0 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/7962:rplp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1M7E5 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/7962:LOC109080541 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLE1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109079281 ^@ http://purl.uniprot.org/uniprot/A0A8C1KP53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/7962:LOC109052010 ^@ http://purl.uniprot.org/uniprot/A0A8C1UL64|||http://purl.uniprot.org/uniprot/A0A8C1YXX4|||http://purl.uniprot.org/uniprot/A0A8C2IWD3 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109073090 ^@ http://purl.uniprot.org/uniprot/A0A8C1QBE2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:ccnb1 ^@ http://purl.uniprot.org/uniprot/A0A8C1WFF3 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109087782 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6W6 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109058130 ^@ http://purl.uniprot.org/uniprot/A0A8C1HN75 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/7962:LOC109069353 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:tmem263 ^@ http://purl.uniprot.org/uniprot/A0A8C1XBM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM263 family.|||Membrane http://togogenome.org/gene/7962:npm3 ^@ http://purl.uniprot.org/uniprot/A0A8C1PB89 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/7962:LOC109045136 ^@ http://purl.uniprot.org/uniprot/A0A8C1AWL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bombesin/neuromedin-B/ranatensin family.|||Secreted|||secretory vesicle lumen http://togogenome.org/gene/7962:pcna ^@ http://purl.uniprot.org/uniprot/A0A8C2GWU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/7962:eloca ^@ http://purl.uniprot.org/uniprot/A0A8C1SHA2 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/7962:LOC109072871 ^@ http://purl.uniprot.org/uniprot/A0A8C1CD95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EGR C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109113455 ^@ http://purl.uniprot.org/uniprot/A0A8C0YUI7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:endog ^@ http://purl.uniprot.org/uniprot/A0A8C2A708 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/7962:tmem234 ^@ http://purl.uniprot.org/uniprot/A0A8C1APQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM234 family.|||Membrane http://togogenome.org/gene/7962:asip2b ^@ http://purl.uniprot.org/uniprot/G7ZL02 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109106864 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:LOC109110334 ^@ http://purl.uniprot.org/uniprot/Q0KHD4 ^@ Similarity ^@ Belongs to the leptin family. http://togogenome.org/gene/7962:pmchl ^@ http://purl.uniprot.org/uniprot/A0A8C1WGZ0 ^@ Function ^@ Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH. http://togogenome.org/gene/7962:LOC109045896 ^@ http://purl.uniprot.org/uniprot/A0A8C1E838 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA7 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7962:LOC109096124 ^@ http://purl.uniprot.org/uniprot/A0A8C1EX29 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109070796 ^@ http://purl.uniprot.org/uniprot/A0A8C2FQ75 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109052175 ^@ http://purl.uniprot.org/uniprot/A0A8C1HH23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0239 family.|||Membrane http://togogenome.org/gene/7962:pias4a ^@ http://purl.uniprot.org/uniprot/A0A8C1H4D2 ^@ Similarity ^@ Belongs to the PIAS family. http://togogenome.org/gene/7962:irgf1 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y881 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/7962:dynlt3 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y7I6 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7962:LOC109045272 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQE3 ^@ Similarity ^@ Belongs to the PIGH family. http://togogenome.org/gene/7962:dnase1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YEJ6 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/7962:LOC109080838 ^@ http://purl.uniprot.org/uniprot/A0A8C1EWS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCC family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109092136 ^@ http://purl.uniprot.org/uniprot/A0A8C1JUT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polycystin family.|||Membrane http://togogenome.org/gene/7962:LOC109091427 ^@ http://purl.uniprot.org/uniprot/A0A8C2KAQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRBN family.|||Nucleus http://togogenome.org/gene/7962:LOC109092575 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFU0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109082865 ^@ http://purl.uniprot.org/uniprot/A0A8C1K3B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109093037 ^@ http://purl.uniprot.org/uniprot/A0A8C2HNW2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/7962:LOC109057002 ^@ http://purl.uniprot.org/uniprot/A0A8C1E2P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109111648 ^@ http://purl.uniprot.org/uniprot/A0A8C2L333 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DSS1/SEM1 family.|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.|||Nucleus http://togogenome.org/gene/7962:LOC109050564 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKW3 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/7962:ckmb ^@ http://purl.uniprot.org/uniprot/Q9YI14 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/7962:mafbb ^@ http://purl.uniprot.org/uniprot/A0A8C1EKU1 ^@ Similarity ^@ Belongs to the bZIP family. Maf subfamily. http://togogenome.org/gene/7962:prr15la ^@ http://purl.uniprot.org/uniprot/A0A8C1E515 ^@ Similarity ^@ Belongs to the PRR15 family. http://togogenome.org/gene/7962:LOC109071637 ^@ http://purl.uniprot.org/uniprot/A0A8C1CVD8 ^@ Similarity ^@ Belongs to the Cdt1 family. http://togogenome.org/gene/7962:LOC109088547 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJ29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSU72 phosphatase family.|||Nucleus|||Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. http://togogenome.org/gene/7962:unc119.1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YM39 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/7962:ebi3 ^@ http://purl.uniprot.org/uniprot/A0A8C1V8G2 ^@ Similarity ^@ Belongs to the type I cytokine receptor family. Type 3 subfamily. http://togogenome.org/gene/7962:si:ch211-151p13.8 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1L6 ^@ Similarity ^@ Belongs to the UPF0687 family. http://togogenome.org/gene/7962:dxo ^@ http://purl.uniprot.org/uniprot/A0A8C1CPQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DXO/Dom3Z family.|||Binds 2 magnesium ions.|||Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.|||Nucleus http://togogenome.org/gene/7962:LOC109068087 ^@ http://purl.uniprot.org/uniprot/A0A8C1MQA4 ^@ Function|||Similarity ^@ Belongs to the profilin family.|||Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. http://togogenome.org/gene/7962:LOC109057005 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JUPITER family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109094022 ^@ http://purl.uniprot.org/uniprot/A0A8C1CY93 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:tmem53 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM53 family.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/7962:pik3r3b ^@ http://purl.uniprot.org/uniprot/A0A8C1HVL9 ^@ Similarity ^@ Belongs to the PI3K p85 subunit family. http://togogenome.org/gene/7962:triqk ^@ http://purl.uniprot.org/uniprot/A0A8C2E0G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIQK family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109061575 ^@ http://purl.uniprot.org/uniprot/A0A8C1E870 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:unc50 ^@ http://purl.uniprot.org/uniprot/A0A8C2GTQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane|||Nucleus inner membrane http://togogenome.org/gene/7962:LOC109092211 ^@ http://purl.uniprot.org/uniprot/A0A8C1NZ19 ^@ Similarity ^@ Belongs to the NUPR family. http://togogenome.org/gene/7962:LOC109092262 ^@ http://purl.uniprot.org/uniprot/A0A8C1P798 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Choline transporter.|||Membrane http://togogenome.org/gene/7962:LOC109112466 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3M1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/7962:fibpb ^@ http://purl.uniprot.org/uniprot/A0A8C1BGA8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109094229 ^@ http://purl.uniprot.org/uniprot/A0A8C1BMT0 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109102937 ^@ http://purl.uniprot.org/uniprot/A0A8C1B299 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109072257 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1A9 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/7962:LOC109073184 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109093548 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109049622 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109087177 ^@ http://purl.uniprot.org/uniprot/A0A8C1RFU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109081605 ^@ http://purl.uniprot.org/uniprot/A0A8C2D828 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/7962:miox ^@ http://purl.uniprot.org/uniprot/A0A8C1IMW1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the myo-inositol oxygenase family.|||Binds 2 iron ions per subunit.|||Cytoplasm http://togogenome.org/gene/7962:LOC109088850 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/7962:LOC109061360 ^@ http://purl.uniprot.org/uniprot/A0A8C1CKJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted|||VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. http://togogenome.org/gene/7962:gtf2b ^@ http://purl.uniprot.org/uniprot/A0A8C2L9Q4 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/7962:hoxc4a ^@ http://purl.uniprot.org/uniprot/A0A8C1BCU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109056548 ^@ http://purl.uniprot.org/uniprot/A0A8C1RGX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/7962:LOC109094355 ^@ http://purl.uniprot.org/uniprot/A0A8C2KMQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/7962:LOC109090439 ^@ http://purl.uniprot.org/uniprot/A0A8C1AB49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC10 family.|||Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.|||flagellum axoneme http://togogenome.org/gene/7962:LOC109056779 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:ago4 ^@ http://purl.uniprot.org/uniprot/A0A8C1ATN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the argonaute family. Ago subfamily.|||P-body|||Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. http://togogenome.org/gene/7962:LOC109109142 ^@ http://purl.uniprot.org/uniprot/A0A8C1BCH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:LOC109110705 ^@ http://purl.uniprot.org/uniprot/A0A8C0YHB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109047720 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:LOC109072495 ^@ http://purl.uniprot.org/uniprot/A0A8C1W742 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109106106 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109056717 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fascin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109106107 ^@ http://purl.uniprot.org/uniprot/A0A8C1AD84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109098588 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y6K6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/7962:LOC109065670 ^@ http://purl.uniprot.org/uniprot/A0A8C1FTK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP18 family.|||Nucleus speckle http://togogenome.org/gene/7962:tceanc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1PGE0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109097880 ^@ http://purl.uniprot.org/uniprot/A0A8C1W6H8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:chmp2ba ^@ http://purl.uniprot.org/uniprot/A0A8C1DJS9 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:LOC122133969 ^@ http://purl.uniprot.org/uniprot/A0A8C1U9A7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/7962:prpf38b ^@ http://purl.uniprot.org/uniprot/A0A8C1D4J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||May be required for pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/7962:borcs8 ^@ http://purl.uniprot.org/uniprot/A0A8C1L4M9|||http://purl.uniprot.org/uniprot/A0A8C1WFC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS8 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109110277 ^@ http://purl.uniprot.org/uniprot/A0A8C1JIP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/7962:LOC109064048 ^@ http://purl.uniprot.org/uniprot/A0A8C1MLM7 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/7962:LOC109096805 ^@ http://purl.uniprot.org/uniprot/A0A8C2G3H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109078044 ^@ http://purl.uniprot.org/uniprot/A0A8C1MB61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/7962:LOC109093341 ^@ http://purl.uniprot.org/uniprot/A0A8C1BKK6 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/7962:LOC109050013 ^@ http://purl.uniprot.org/uniprot/A0A8C1NRL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:cfap97d2 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1W6 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/7962:LOC109088654 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJ72 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109094878 ^@ http://purl.uniprot.org/uniprot/A0A8C1G2X2 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/7962:LOC109094614 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109088095 ^@ http://purl.uniprot.org/uniprot/A0A8C2GPA6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109066734 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZM83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109105126 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6X9 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/7962:LOC109070894 ^@ http://purl.uniprot.org/uniprot/A0A8C1PL10 ^@ Similarity ^@ Belongs to the RRM HNRPC family. RALY subfamily. http://togogenome.org/gene/7962:LOC109097769 ^@ http://purl.uniprot.org/uniprot/A0A8C1I626 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Secreted http://togogenome.org/gene/7962:LOC109100618 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVR5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109060599 ^@ http://purl.uniprot.org/uniprot/A0A8C1GN36 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109078881 ^@ http://purl.uniprot.org/uniprot/A0A8C1US92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:efnb2a ^@ http://purl.uniprot.org/uniprot/A0A8C1KJZ5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109061841 ^@ http://purl.uniprot.org/uniprot/A0A8C1VMD6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109109072 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMF5 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/7962:LOC109066461 ^@ http://purl.uniprot.org/uniprot/A0A8C1DSP1 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase family.|||Homodimer. http://togogenome.org/gene/7962:LOC109063441 ^@ http://purl.uniprot.org/uniprot/A0A8C1E9I7 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109110167 ^@ http://purl.uniprot.org/uniprot/A0A8C1AD31 ^@ Similarity ^@ Belongs to the glutaminyl-peptide cyclotransferase family. http://togogenome.org/gene/7962:LOC109053130 ^@ http://purl.uniprot.org/uniprot/A0A8C1I593 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fascin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109057723 ^@ http://purl.uniprot.org/uniprot/A0A8C1TP74 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:dph3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTQ4 ^@ Similarity ^@ Belongs to the DPH3 family. http://togogenome.org/gene/7962:LOC109090126 ^@ http://purl.uniprot.org/uniprot/A0A8C1D770 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109091509 ^@ http://purl.uniprot.org/uniprot/A0A8C1C3E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109072362 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJV5 ^@ Similarity ^@ Belongs to the LECT2/MIM-1 family. http://togogenome.org/gene/7962:LOC109084690 ^@ http://purl.uniprot.org/uniprot/A0A8C1KPP3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109091860 ^@ http://purl.uniprot.org/uniprot/A0A8C1GYW5 ^@ Similarity ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. http://togogenome.org/gene/7962:LOC109083035 ^@ http://purl.uniprot.org/uniprot/A0A8C1E310 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109045693 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bombesin/neuromedin-B/ranatensin family.|||Secreted|||secretory vesicle lumen http://togogenome.org/gene/7962:LOC109111742 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109076645 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 63 family.|||Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109051158 ^@ http://purl.uniprot.org/uniprot/A0A8C1DW27 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:hikeshi ^@ http://purl.uniprot.org/uniprot/A0A8C0XYU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.|||Belongs to the OPI10 family.|||Cytoplasm|||Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.|||Nucleus|||cytosol http://togogenome.org/gene/7962:LOC109047269 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABN9 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:LOC109067118 ^@ http://purl.uniprot.org/uniprot/A0A8C1IQC0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109072367 ^@ http://purl.uniprot.org/uniprot/A0A8C1ELH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Polycomblike family.|||Nucleus http://togogenome.org/gene/7962:LOC109072933 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/7962:samd8 ^@ http://purl.uniprot.org/uniprot/A0A8C2EBL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/7962:alkal1 ^@ http://purl.uniprot.org/uniprot/A0A8C1F4A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALKAL family.|||Secreted http://togogenome.org/gene/7962:hmx2 ^@ http://purl.uniprot.org/uniprot/A0A8C2HQ53 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109060979 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5H7 ^@ Similarity ^@ Belongs to the dermatopontin family. http://togogenome.org/gene/7962:timm13 ^@ http://purl.uniprot.org/uniprot/A0A8C2CCT4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7962:dlx2a ^@ http://purl.uniprot.org/uniprot/A0A8C1CBM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the distal-less homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109065818 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||Secreted http://togogenome.org/gene/7962:LOC109055905 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/7962:LOC109072786 ^@ http://purl.uniprot.org/uniprot/A0A8C1PC29|||http://purl.uniprot.org/uniprot/A0A8C1PMP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/7962:LOC109053166 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJ28 ^@ Similarity ^@ Belongs to the NARF family. http://togogenome.org/gene/7962:LOC109074729 ^@ http://purl.uniprot.org/uniprot/A0A8C1HSR6 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:rab32a ^@ http://purl.uniprot.org/uniprot/A0A8C1E851 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:hddc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HDDC2 family.|||Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).|||Homodimer. http://togogenome.org/gene/7962:myadmb ^@ http://purl.uniprot.org/uniprot/A0A8C1HT18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109090633 ^@ http://purl.uniprot.org/uniprot/A0A8C1DAJ9 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109060208 ^@ http://purl.uniprot.org/uniprot/A0A8C1S4P1 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109065643 ^@ http://purl.uniprot.org/uniprot/A0A8C1DPS1 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109053953 ^@ http://purl.uniprot.org/uniprot/A0A8C2I865 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hcp beta-lactamase family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:gamt ^@ http://purl.uniprot.org/uniprot/A0A8C2IX80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.|||Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.|||Monomer. http://togogenome.org/gene/7962:ldb1a ^@ http://purl.uniprot.org/uniprot/A0A8C1A9R9|||http://purl.uniprot.org/uniprot/A0A8C2AA86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LDB family.|||Nucleus http://togogenome.org/gene/7962:bicd1a ^@ http://purl.uniprot.org/uniprot/A0A8C1F0A8|||http://purl.uniprot.org/uniprot/A0A8C1F729 ^@ Similarity ^@ Belongs to the BicD family. http://togogenome.org/gene/7962:LOC109053053 ^@ http://purl.uniprot.org/uniprot/A0A0C6ESZ2|||http://purl.uniprot.org/uniprot/A0A8C0YH77|||http://purl.uniprot.org/uniprot/A0A8C1QW02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||dendrite|||filopodium|||growth cone|||sarcolemma http://togogenome.org/gene/7962:LOC109060703 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:si:ch211-284o19.8 ^@ http://purl.uniprot.org/uniprot/A0A8C2AIA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/7962:fgf13a ^@ http://purl.uniprot.org/uniprot/A0A0C6ESZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||dendrite|||filopodium|||growth cone|||sarcolemma http://togogenome.org/gene/7962:LOC109088915 ^@ http://purl.uniprot.org/uniprot/A0A8C1I3E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109051957 ^@ http://purl.uniprot.org/uniprot/A0A8C1M207 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/7962:LOC109055492 ^@ http://purl.uniprot.org/uniprot/A0A8C1BAB3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109051891 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFK7 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109055449 ^@ http://purl.uniprot.org/uniprot/A0A8C1WU84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109067124 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIK1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109105977 ^@ http://purl.uniprot.org/uniprot/A0A8C2I9S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/7962:LOC109073666 ^@ http://purl.uniprot.org/uniprot/A0A8C2JBV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:LOC109046515 ^@ http://purl.uniprot.org/uniprot/A0A8C1KBL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:gstt1a ^@ http://purl.uniprot.org/uniprot/A0A0M5MYW1 ^@ Similarity ^@ Belongs to the GST superfamily. Theta family. http://togogenome.org/gene/7962:LOC109097411 ^@ http://purl.uniprot.org/uniprot/A0A8C1VLL4 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109077480 ^@ http://purl.uniprot.org/uniprot/A0A8C1ENE2 ^@ Similarity ^@ Belongs to the RGS7BP/RGS9BP family. http://togogenome.org/gene/7962:LOC109088225 ^@ http://purl.uniprot.org/uniprot/A0A8C1UI92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-delta family.|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:LOC109090603 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFX8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109068760 ^@ http://purl.uniprot.org/uniprot/A0A5Q2UCG2 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109083545 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3B6 ^@ Similarity ^@ Belongs to the ANKRD34 family. http://togogenome.org/gene/7962:LOC109080238 ^@ http://purl.uniprot.org/uniprot/A0A8C1U7H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109056796 ^@ http://purl.uniprot.org/uniprot/A0A089ZZB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109088183 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP298 family.|||cilium basal body http://togogenome.org/gene/7962:LOC109072379 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMP1 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. AMIGO family. http://togogenome.org/gene/7962:prorp ^@ http://purl.uniprot.org/uniprot/A0A8C1A3H5 ^@ Similarity ^@ Belongs to the PPR family. P subfamily. http://togogenome.org/gene/7962:bmp6 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZB7 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:suv39h1a ^@ http://purl.uniprot.org/uniprot/A0A8C1UQD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.|||Nucleus|||centromere http://togogenome.org/gene/7962:actb1 ^@ http://purl.uniprot.org/uniprot/A0A8C1PZH7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:hspb2 ^@ http://purl.uniprot.org/uniprot/A0A8C1DGK8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109102993 ^@ http://purl.uniprot.org/uniprot/A0A8C1YMA6 ^@ Similarity ^@ Belongs to the fibroblast growth factor-binding protein family. http://togogenome.org/gene/7962:LOC109110999 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRT1 ^@ Function|||Similarity ^@ Belongs to the VPS28 family.|||Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. http://togogenome.org/gene/7962:LOC109106291 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y5Z8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109101902 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3C5 ^@ Subcellular Location Annotation ^@ Secreted|||Synapse http://togogenome.org/gene/7962:LOC109064416 ^@ http://purl.uniprot.org/uniprot/A0A8C1GPE9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109059339 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFU3 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/7962:LOC109067315 ^@ http://purl.uniprot.org/uniprot/A0A8C1FMU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPP2 family.|||Could coordinate an aspect of bone turnover.|||Secreted http://togogenome.org/gene/7962:LOC109103435 ^@ http://purl.uniprot.org/uniprot/A0A8C0YNU3 ^@ Similarity|||Subunit ^@ Homohexamer.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/7962:LOC109049216 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZJ50 ^@ Similarity ^@ Belongs to the CD99 family. http://togogenome.org/gene/7962:LOC109050658 ^@ http://purl.uniprot.org/uniprot/A0A0C6EMI3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:serpina10a ^@ http://purl.uniprot.org/uniprot/A0A8C1ES64 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109108968 ^@ http://purl.uniprot.org/uniprot/A0A8C1VUK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/7962:LOC109079099 ^@ http://purl.uniprot.org/uniprot/A0A8C2D6Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109060426 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8N6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109069788 ^@ http://purl.uniprot.org/uniprot/A0A8C1GVW1 ^@ Function|||Similarity ^@ Belongs to the MOZART1 family.|||Required for gamma-tubulin complex recruitment to the centrosome. http://togogenome.org/gene/7962:LOC109079422 ^@ http://purl.uniprot.org/uniprot/A0A8C1D5Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.|||Nucleus|||cytosol http://togogenome.org/gene/7962:LOC109093883 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q1U6 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:tnfsf13b ^@ http://purl.uniprot.org/uniprot/A0A8C1S6T0 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7962:nkx2.4b ^@ http://purl.uniprot.org/uniprot/A0A8C1WN62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109056364 ^@ http://purl.uniprot.org/uniprot/A0A8C1ENU2 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:pin4 ^@ http://purl.uniprot.org/uniprot/A0A8C2A1B0 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily. http://togogenome.org/gene/7962:rpl27 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL27 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum http://togogenome.org/gene/7962:LOC109105722 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3A8 ^@ Similarity ^@ Belongs to the FAM131 family. http://togogenome.org/gene/7962:cfl1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AWS7 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/7962:myf6 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBM2 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:LOC109048673 ^@ http://purl.uniprot.org/uniprot/A0A8C1ALY8 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/7962:LOC109059989 ^@ http://purl.uniprot.org/uniprot/A0A8C1CPF5|||http://purl.uniprot.org/uniprot/A0A8C2DHX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CTF/NF-I family.|||Binds DNA as a homodimer.|||Nucleus|||Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. http://togogenome.org/gene/7962:LOC109071960 ^@ http://purl.uniprot.org/uniprot/K4Q5C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109105956 ^@ http://purl.uniprot.org/uniprot/A0A8C1ATD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZHX family.|||Nucleus http://togogenome.org/gene/7962:LOC109104050 ^@ http://purl.uniprot.org/uniprot/A0A8C1L472 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITPRIP family.|||Membrane http://togogenome.org/gene/7962:LOC109111626 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMP3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:oxt ^@ http://purl.uniprot.org/uniprot/A0A8C1KVG2 ^@ Similarity ^@ Belongs to the vasopressin/oxytocin family. http://togogenome.org/gene/7962:LOC109102249 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4F4|||http://purl.uniprot.org/uniprot/A0A8C0Y551|||http://purl.uniprot.org/uniprot/A0A8C0Y6C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM255 family.|||Membrane http://togogenome.org/gene/7962:LOC109100671 ^@ http://purl.uniprot.org/uniprot/A0A8C1IH22|||http://purl.uniprot.org/uniprot/A0A8C2BEV6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/7962:si:ch211-39i2.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CC86 ^@ Similarity ^@ Belongs to the DDIT4 family. http://togogenome.org/gene/7962:prkacaa ^@ http://purl.uniprot.org/uniprot/A0A8C2B4B3|||http://purl.uniprot.org/uniprot/A0A8C2B636 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/7962:LOC109076812 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRP38 family.|||Component of the spliceosome B complex.|||Involved in pre-mRNA splicing as a component of the spliceosome.|||Nucleus http://togogenome.org/gene/7962:LOC109076576 ^@ http://purl.uniprot.org/uniprot/A0A8C2BVH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SDHAF2 family.|||Interacts with SDHA within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. http://togogenome.org/gene/7962:LOC109077925 ^@ http://purl.uniprot.org/uniprot/A0A8C2JN70 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/7962:LOC109071127 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLS2 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109101093 ^@ http://purl.uniprot.org/uniprot/G8EFS9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/7962:LOC109090336 ^@ http://purl.uniprot.org/uniprot/A0A8C1CSG7 ^@ Subcellular Location Annotation ^@ nucleoplasm http://togogenome.org/gene/7962:LOC109048914 ^@ http://purl.uniprot.org/uniprot/A0A8C2KKD4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109046614 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3Q6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPCAM family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109096011 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFI8 ^@ Similarity ^@ Belongs to the RAMP family. http://togogenome.org/gene/7962:LOC109045429 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJ54 ^@ Subcellular Location Annotation ^@ mitochondrion nucleoid http://togogenome.org/gene/7962:LOC109059295 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Membrane|||cytosol http://togogenome.org/gene/7962:LOC109104892 ^@ http://purl.uniprot.org/uniprot/A0A8C1GWR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109070452 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109053853 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3Z8 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109065626 ^@ http://purl.uniprot.org/uniprot/A0A8C1DD56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/7962:LOC109110898 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Membrane http://togogenome.org/gene/7962:txnl4b ^@ http://purl.uniprot.org/uniprot/A0A8C2KDQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/7962:LOC109087390 ^@ http://purl.uniprot.org/uniprot/A0A8C1RKY7 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109113172 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCX0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109064987 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFC9 ^@ Function|||Similarity ^@ Belongs to the cytidylyltransferase family.|||Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. http://togogenome.org/gene/7962:LOC109102631 ^@ http://purl.uniprot.org/uniprot/A0A8C1BCF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MTURN family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109060330 ^@ http://purl.uniprot.org/uniprot/A0A8C1R8K8 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:mcur1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ENQ8 ^@ Similarity ^@ Belongs to the CCDC90 family. http://togogenome.org/gene/7962:LOC109088356 ^@ http://purl.uniprot.org/uniprot/A0A8C2KX17 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:adhfe1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Mitochondrion http://togogenome.org/gene/7962:map6b ^@ http://purl.uniprot.org/uniprot/A0A8C1EXX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STOP family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109095987 ^@ http://purl.uniprot.org/uniprot/A0A8C0XYU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/7962:b3gnt7l ^@ http://purl.uniprot.org/uniprot/A0A8C1Y635 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109062851 ^@ http://purl.uniprot.org/uniprot/A0A8C1IVE5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109067252 ^@ http://purl.uniprot.org/uniprot/A0A8C1H5G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CART family.|||Secreted http://togogenome.org/gene/7962:LOC109045170 ^@ http://purl.uniprot.org/uniprot/A0A8C1MJJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/7962:LOC109106083 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y172 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/7962:nhp2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FS32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/7962:LOC109046778 ^@ http://purl.uniprot.org/uniprot/A0A8C1J829 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:yes1 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y1N8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109055390 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZB5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109099407 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109095204 ^@ http://purl.uniprot.org/uniprot/A0A8C2PLK1 ^@ Similarity ^@ Belongs to the RGS7BP/RGS9BP family. http://togogenome.org/gene/7962:LOC109064465 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZA0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. http://togogenome.org/gene/7962:LOC109071097 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z5Y5 ^@ Similarity ^@ Belongs to the UPF0430 family. http://togogenome.org/gene/7962:LOC109093151 ^@ http://purl.uniprot.org/uniprot/A0A8C2IY01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/7962:LOC109064294 ^@ http://purl.uniprot.org/uniprot/A0A8C1GEN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109062817 ^@ http://purl.uniprot.org/uniprot/A0A8C2EVK4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sf3b6 ^@ http://purl.uniprot.org/uniprot/A0A8C1C654 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109101731 ^@ http://purl.uniprot.org/uniprot/A0A8C1BE23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.|||Nucleus http://togogenome.org/gene/7962:LOC109095289 ^@ http://purl.uniprot.org/uniprot/A0A8C1B1P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NKAIN family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:fam161b ^@ http://purl.uniprot.org/uniprot/A0A8C1DEB5 ^@ Similarity ^@ Belongs to the FAM161 family. http://togogenome.org/gene/7962:LOC109100122 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQE9 ^@ Function|||Similarity ^@ Belongs to the peptidase M54 family.|||Probable zinc metalloprotease. http://togogenome.org/gene/7962:LOC109069385 ^@ http://purl.uniprot.org/uniprot/A0A8C1FWC3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109083034 ^@ http://purl.uniprot.org/uniprot/A0A8C1DW12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATR family.|||Membrane http://togogenome.org/gene/7962:lasp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJC3 ^@ Function|||Subcellular Location Annotation ^@ Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.|||cell cortex|||cytoskeleton http://togogenome.org/gene/7962:LOC109058440 ^@ http://purl.uniprot.org/uniprot/A0A8C1NU90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the apolipoprotein C2 family.|||Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.|||Secreted http://togogenome.org/gene/7962:il1b ^@ http://purl.uniprot.org/uniprot/L0H4I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-1 family.|||Lysosome|||cytosol|||extracellular exosome http://togogenome.org/gene/7962:LOC109054698 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:mturn ^@ http://purl.uniprot.org/uniprot/A0A8C2D305 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MTURN family.|||Cytoplasm http://togogenome.org/gene/7962:nox1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HXT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:serf2a ^@ http://purl.uniprot.org/uniprot/A0A8C1G2F5 ^@ Similarity ^@ Belongs to the SERF family. http://togogenome.org/gene/7962:LOC109085761 ^@ http://purl.uniprot.org/uniprot/A0A8C1IW07|||http://purl.uniprot.org/uniprot/A0A8C1IW63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109058940 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/7962:LOC109101685 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109074968 ^@ http://purl.uniprot.org/uniprot/A0A8C1A146 ^@ Function|||Similarity ^@ Anti-proliferative protein.|||Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109051058 ^@ http://purl.uniprot.org/uniprot/A0A8C1K9A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST5 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7962:gsc ^@ http://purl.uniprot.org/uniprot/A0A8C2CX62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109096504 ^@ http://purl.uniprot.org/uniprot/A0A8C1M463 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109107106 ^@ http://purl.uniprot.org/uniprot/A0A8C1ETG0 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/7962:LOC109053090 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM54 family.|||Membrane http://togogenome.org/gene/7962:LOC109084126 ^@ http://purl.uniprot.org/uniprot/A0A8C1S173 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109056361 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX28 ^@ Function|||Similarity ^@ Belongs to the calponin family.|||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. http://togogenome.org/gene/7962:gnrh2 ^@ http://purl.uniprot.org/uniprot/Q7ZT17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GnRH family.|||Secreted|||Stimulates the secretion of gonadotropins. http://togogenome.org/gene/7962:LOC109108094 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y0L4 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/7962:LOC109055649 ^@ http://purl.uniprot.org/uniprot/A0A8C1U578 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:tagln3b ^@ http://purl.uniprot.org/uniprot/A0A8C1WCA2 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/7962:LOC109079204 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX72 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/7962:LOC109088027 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQU3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109058278 ^@ http://purl.uniprot.org/uniprot/A0A8C1U688 ^@ Similarity ^@ Belongs to the TAPR1 family. http://togogenome.org/gene/7962:LOC109048345 ^@ http://purl.uniprot.org/uniprot/A0A8C1QF38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/7962:si:ch211-121a2.4 ^@ http://purl.uniprot.org/uniprot/A0A8C2EL02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM205 family.|||Membrane http://togogenome.org/gene/7962:LOC109091471 ^@ http://purl.uniprot.org/uniprot/A0A8C1VUM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:mtch2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109045315 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQR9 ^@ Similarity ^@ Belongs to the prenylcysteine oxidase family. http://togogenome.org/gene/7962:naa38 ^@ http://purl.uniprot.org/uniprot/A0A8C1BTY0 ^@ Function|||Similarity|||Subunit ^@ Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.|||Belongs to the snRNP Sm proteins family.|||Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30. http://togogenome.org/gene/7962:mb ^@ http://purl.uniprot.org/uniprot/M4QSG1 ^@ Function|||Similarity ^@ Belongs to the globin family.|||Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. http://togogenome.org/gene/7962:LOC109095941 ^@ http://purl.uniprot.org/uniprot/A0A8C1JK33 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/7962:LOC109090907 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYQ1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/7962:LOC109054051 ^@ http://purl.uniprot.org/uniprot/A0A8C1A445 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. ABHD16 family.|||Membrane http://togogenome.org/gene/7962:ip6k2b ^@ http://purl.uniprot.org/uniprot/A0A8C1ATW8 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:mmp28 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3Y4 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/7962:LOC109090569 ^@ http://purl.uniprot.org/uniprot/A0A8C2HGA7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109061210 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTY5 ^@ Similarity ^@ Belongs to the glycosyltransferase 61 family. http://togogenome.org/gene/7962:LOC109111726 ^@ http://purl.uniprot.org/uniprot/A0A8C1P7Y4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NKD family.|||Cell autonomous antagonist of the canonical Wnt signaling pathway.|||Cell membrane|||Cytoplasm|||Membrane http://togogenome.org/gene/7962:LOC109108127 ^@ http://purl.uniprot.org/uniprot/A0A8C1DHH8|||http://purl.uniprot.org/uniprot/A0A8C1HMU5 ^@ Similarity ^@ Belongs to the YY transcription factor family. http://togogenome.org/gene/7962:LOC109093088 ^@ http://purl.uniprot.org/uniprot/A0A8C2DBB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/7962:LOC109046479 ^@ http://purl.uniprot.org/uniprot/A0A8C1H2S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109062266 ^@ http://purl.uniprot.org/uniprot/A0A8C1AIP3 ^@ Function|||Subcellular Location Annotation ^@ Endomembrane system|||Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.|||filopodium|||microvillus|||ruffle http://togogenome.org/gene/7962:LOC109075069 ^@ http://purl.uniprot.org/uniprot/A0A8C1K136 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/7962:fgf8b ^@ http://purl.uniprot.org/uniprot/A0A8C1GBY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/7962:csrnp2 ^@ http://purl.uniprot.org/uniprot/A0A8C1H051 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109064041 ^@ http://purl.uniprot.org/uniprot/A0A8C1BF84 ^@ Similarity ^@ Belongs to the CCDC43 family. http://togogenome.org/gene/7962:LOC109083151 ^@ http://purl.uniprot.org/uniprot/A0A8C1PCA1 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/7962:LOC109065208 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cystinosin family.|||Membrane http://togogenome.org/gene/7962:cd9b ^@ http://purl.uniprot.org/uniprot/A0A8C1EDF6|||http://purl.uniprot.org/uniprot/A0A8C1HTW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Cell membrane|||Membrane|||extracellular exosome http://togogenome.org/gene/7962:hoxd13a ^@ http://purl.uniprot.org/uniprot/A0A8C1A268 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:rxfp3.3a3 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6K4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109103575 ^@ http://purl.uniprot.org/uniprot/A0A8C1DB69 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.|||Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.|||extracellular space|||nucleoplasm|||sarcolemma http://togogenome.org/gene/7962:LOC109104968 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8E0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the serpin family.|||Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.|||Secreted|||Stimulates aldosterone release. http://togogenome.org/gene/7962:LOC109056404 ^@ http://purl.uniprot.org/uniprot/A0A8C2EZ06 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:LOC109046124 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109070624 ^@ http://purl.uniprot.org/uniprot/A0A8C1V9Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/7962:LOC109112546 ^@ http://purl.uniprot.org/uniprot/A0A8C1AT95 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109092992 ^@ http://purl.uniprot.org/uniprot/A0A8C2BTT0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109100822 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2K7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109074224 ^@ http://purl.uniprot.org/uniprot/A0A8C1LXL5 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109068791 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109048156 ^@ http://purl.uniprot.org/uniprot/A0A8C1BF45 ^@ Similarity ^@ Belongs to the RIB43A family. http://togogenome.org/gene/7962:LOC109091712 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXE4 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:fgfr1op2 ^@ http://purl.uniprot.org/uniprot/A0A8C1PH77 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/7962:LOC109087142 ^@ http://purl.uniprot.org/uniprot/A0A8C2G3K6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7962:fxr2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVS5 ^@ Similarity ^@ Belongs to the FMR1 family. http://togogenome.org/gene/7962:LOC109052226 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Deltex family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109065562 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/7962:LOC109046568 ^@ http://purl.uniprot.org/uniprot/A0A8C1KB39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109052390 ^@ http://purl.uniprot.org/uniprot/A0A8C1JGV2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.|||Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. http://togogenome.org/gene/7962:stx11a ^@ http://purl.uniprot.org/uniprot/A0A8C1A8Y7 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109065422 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily.|||Cytoplasm|||Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.|||Nucleus|||Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions. http://togogenome.org/gene/7962:LOC109048263 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase VIIc family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109049255 ^@ http://purl.uniprot.org/uniprot/A0A8C1IVB3 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/7962:LOC109098086 ^@ http://purl.uniprot.org/uniprot/A0A8C1BL50 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109097444 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Endosome membrane|||Late endosome membrane http://togogenome.org/gene/7962:LOC109055674 ^@ http://purl.uniprot.org/uniprot/A0A8C1XSP5 ^@ Function|||Similarity ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. http://togogenome.org/gene/7962:ndufb2 ^@ http://purl.uniprot.org/uniprot/A0A8C1WCZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109052581 ^@ http://purl.uniprot.org/uniprot/A0A8C2FJ83 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:taf4b ^@ http://purl.uniprot.org/uniprot/A0A8C0Y9K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF4 family.|||Nucleus http://togogenome.org/gene/7962:LOC109111500 ^@ http://purl.uniprot.org/uniprot/A0A8C1APY2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 33 family. http://togogenome.org/gene/7962:LOC109113655 ^@ http://purl.uniprot.org/uniprot/A0A8C1FET1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109064543 ^@ http://purl.uniprot.org/uniprot/A0A8C1G183 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/7962:LOC109099020 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109090889 ^@ http://purl.uniprot.org/uniprot/A0A8C1TU51 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109099024 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XPO2/CSE1 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109101589 ^@ http://purl.uniprot.org/uniprot/A0A8C1CDT9 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109049137 ^@ http://purl.uniprot.org/uniprot/A0A8C1H4G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPC2 family.|||Secreted http://togogenome.org/gene/7962:LOC109105073 ^@ http://purl.uniprot.org/uniprot/A0A8C1TZ72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GAMAD family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/7962:LOC109056374 ^@ http://purl.uniprot.org/uniprot/A0A8C1FA37 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109066254 ^@ http://purl.uniprot.org/uniprot/A0A8C1L3S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fascin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109058582 ^@ http://purl.uniprot.org/uniprot/A0A8C1HEJ8 ^@ Similarity ^@ Belongs to the MIX23 family. http://togogenome.org/gene/7962:gpr37l1a ^@ http://purl.uniprot.org/uniprot/A0A8C1EKP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109050012 ^@ http://purl.uniprot.org/uniprot/A0A8C1J9M4 ^@ Similarity ^@ Belongs to the FAM219 family. http://togogenome.org/gene/7962:LOC109071605 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endothelin/sarafotoxin family.|||Secreted http://togogenome.org/gene/7962:ntn4 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSI0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:pip4p2 ^@ http://purl.uniprot.org/uniprot/A0A8C1S1W0 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:map1lc3c ^@ http://purl.uniprot.org/uniprot/A0A8C1CDV2 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109107078 ^@ http://purl.uniprot.org/uniprot/A0A8C1HR57 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:zgc:92744 ^@ http://purl.uniprot.org/uniprot/A0A8C1MC82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane|||May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.|||Membrane http://togogenome.org/gene/7962:LOC109111046 ^@ http://purl.uniprot.org/uniprot/A0A8C1SXM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:LOC109051172 ^@ http://purl.uniprot.org/uniprot/A0A8C1EAM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Chromosome|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/7962:stk3 ^@ http://purl.uniprot.org/uniprot/A0A8C2AN83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109048974 ^@ http://purl.uniprot.org/uniprot/A0A8C1ABQ8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109068658 ^@ http://purl.uniprot.org/uniprot/A0A8C1T1L8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||centrosome|||cilium basal body|||perinuclear region|||spindle http://togogenome.org/gene/7962:LOC109093409 ^@ http://purl.uniprot.org/uniprot/A0A8C2DKZ0 ^@ Similarity ^@ Belongs to the UPF0547 family. http://togogenome.org/gene/7962:LOC109083134 ^@ http://purl.uniprot.org/uniprot/A0A8C1HXZ5 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:gtf2h3 ^@ http://purl.uniprot.org/uniprot/A0A8C2IIV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB4 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.|||Nucleus|||Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7. http://togogenome.org/gene/7962:LOC109062271 ^@ http://purl.uniprot.org/uniprot/A0A8C1NQK4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:KEF38_p10 ^@ http://purl.uniprot.org/uniprot/P24987 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a dinuclear copper A center per subunit.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16 (By similarity).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:polr1h ^@ http://purl.uniprot.org/uniprot/A0A8C1W921 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.|||nucleolus http://togogenome.org/gene/7962:LOC109085017 ^@ http://purl.uniprot.org/uniprot/A0A8C1GM08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Belongs to the chemokine-like receptor (CMKLR) family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109053088 ^@ http://purl.uniprot.org/uniprot/A0A8C1GAS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM54 family.|||Membrane http://togogenome.org/gene/7962:LOC109101603 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLF9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109052669 ^@ http://purl.uniprot.org/uniprot/A0A8C2HQ42 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:LOC109078612 ^@ http://purl.uniprot.org/uniprot/A0A8C1N7X0|||http://purl.uniprot.org/uniprot/A0A8C1TY12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109104722 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y891 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-13 family.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/7962:LOC109096508 ^@ http://purl.uniprot.org/uniprot/A0A8C1WCW6 ^@ Function ^@ Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. http://togogenome.org/gene/7962:LOC109060234 ^@ http://purl.uniprot.org/uniprot/A0A8C2CFH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/7962:LOC109070224 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7D1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109076841 ^@ http://purl.uniprot.org/uniprot/A0A8C1GGD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGP family.|||Membrane|||Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. http://togogenome.org/gene/7962:LOC109073237 ^@ http://purl.uniprot.org/uniprot/A0A8C1GPC5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109084713 ^@ http://purl.uniprot.org/uniprot/A0A8C1FID8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/7962:LOC109113391 ^@ http://purl.uniprot.org/uniprot/A0A8C1CD22 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109053277 ^@ http://purl.uniprot.org/uniprot/A0A8C0YH79|||http://purl.uniprot.org/uniprot/A0A8C2H2A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane http://togogenome.org/gene/7962:LOC109061887 ^@ http://purl.uniprot.org/uniprot/A0A8C1BAF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:cdkn2aipnl ^@ http://purl.uniprot.org/uniprot/A0A8C1B0C3 ^@ Similarity ^@ Belongs to the CARF family. http://togogenome.org/gene/7962:zgc:92907 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQC7 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/7962:LOC109059998 ^@ http://purl.uniprot.org/uniprot/A0A8C1BC60 ^@ Similarity ^@ Belongs to the MHC class I family. http://togogenome.org/gene/7962:LOC109049138 ^@ http://purl.uniprot.org/uniprot/A0A8C1AU29 ^@ Similarity ^@ Belongs to the GSKIP family. http://togogenome.org/gene/7962:LOC109066571 ^@ http://purl.uniprot.org/uniprot/A0A8C1F9R9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109063600 ^@ http://purl.uniprot.org/uniprot/A0A8C1HUD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.|||May be involved in collagen fiber assembly.|||extracellular matrix http://togogenome.org/gene/7962:LOC109105130 ^@ http://purl.uniprot.org/uniprot/A0A8C1YVQ2 ^@ Subcellular Location Annotation ^@ nucleoplasm http://togogenome.org/gene/7962:LOC109099650 ^@ http://purl.uniprot.org/uniprot/A0A8C1A1W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Cell membrane|||Cytoplasmic vesicle|||Endosome|||Membrane|||Perikaryon|||Recycling endosome|||Synaptic cell membrane|||Vesicle|||dendrite http://togogenome.org/gene/7962:LOC109055336 ^@ http://purl.uniprot.org/uniprot/A0A8C1A754 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109082857 ^@ http://purl.uniprot.org/uniprot/A0A8C1L8M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/7962:LOC109055460 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7962:LOC109096110 ^@ http://purl.uniprot.org/uniprot/A0A8C2PM55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109064422 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109054466 ^@ http://purl.uniprot.org/uniprot/A0A8C1DTI4 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/7962:LOC109113311 ^@ http://purl.uniprot.org/uniprot/A0A8C1LIK9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:sfrp1b ^@ http://purl.uniprot.org/uniprot/A0A8C1AE21 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109090421 ^@ http://purl.uniprot.org/uniprot/A0A8C1A712 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109057300 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSK0 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:sdhaf3 ^@ http://purl.uniprot.org/uniprot/A0A8C1JV35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family. SDHAF3 subfamily.|||Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. http://togogenome.org/gene/7962:LOC109104993 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:coq10a ^@ http://purl.uniprot.org/uniprot/A0A8C1AWP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/7962:LOC109097945 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EPO/TPO family.|||Secreted http://togogenome.org/gene/7962:LOC109074111 ^@ http://purl.uniprot.org/uniprot/A0A8C2C8Z2 ^@ Domain|||Function|||Subunit ^@ Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.|||Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.|||The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase. http://togogenome.org/gene/7962:LOC109048523 ^@ http://purl.uniprot.org/uniprot/A0A089ZZB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109056128 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRAK1BP1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:atp6v1h ^@ http://purl.uniprot.org/uniprot/A0A8C1BPW9|||http://purl.uniprot.org/uniprot/A0A8C1P205 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:LOC109057882 ^@ http://purl.uniprot.org/uniprot/A0A515MD70 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:or30bt1 ^@ http://purl.uniprot.org/uniprot/A0A8C1JBD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109074297 ^@ http://purl.uniprot.org/uniprot/A0A8C1MS95|||http://purl.uniprot.org/uniprot/A0A8C1MW79 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:itpkcb ^@ http://purl.uniprot.org/uniprot/A0A8C1H3M5 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:ccdc107 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIL3 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/7962:LOC109049754 ^@ http://purl.uniprot.org/uniprot/A0A8C1AF64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThTPase family.|||Cytoplasm|||Hydrolase highly specific for thiamine triphosphate (ThTP).|||Monomer. http://togogenome.org/gene/7962:LOC109087980 ^@ http://purl.uniprot.org/uniprot/A0A8C1KX55 ^@ Similarity ^@ Belongs to the FAM72 family. http://togogenome.org/gene/7962:LOC109054512 ^@ http://purl.uniprot.org/uniprot/A0A8C2ALY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/7962:LOC109112658 ^@ http://purl.uniprot.org/uniprot/A0A8C1E098 ^@ Similarity ^@ Belongs to the BLOC1S2 family. http://togogenome.org/gene/7962:LOC109086661 ^@ http://purl.uniprot.org/uniprot/A0A090BAU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Cytoplasmic vesicle|||Endoplasmic reticulum|||Membrane|||Nucleus|||Vesicle http://togogenome.org/gene/7962:impa1 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y362 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/7962:hoxc13b ^@ http://purl.uniprot.org/uniprot/A0A8C1A9T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:tmem18 ^@ http://purl.uniprot.org/uniprot/A0A8C1II97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM18 family.|||Membrane|||Nucleus membrane http://togogenome.org/gene/7962:LOC109080386 ^@ http://purl.uniprot.org/uniprot/A0A8C1ECU2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109054699 ^@ http://purl.uniprot.org/uniprot/A0A8C2BMJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109089064 ^@ http://purl.uniprot.org/uniprot/A0A8C1EY75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CWC16 family. YJU2 subfamily.|||Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.|||Nucleus|||Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex. http://togogenome.org/gene/7962:LOC109084642 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4B3 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/7962:LOC109078179 ^@ http://purl.uniprot.org/uniprot/A0A8C1LGE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APC16 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.|||Cytoplasm|||Nucleus|||kinetochore http://togogenome.org/gene/7962:LOC109051932 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHQ6|||http://purl.uniprot.org/uniprot/A0A8C1LDA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.|||Cell membrane|||Membrane|||Midbody|||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. http://togogenome.org/gene/7962:mpc2a ^@ http://purl.uniprot.org/uniprot/A0A8C1X993 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109088929 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109065111 ^@ http://purl.uniprot.org/uniprot/A0A8C1L7L4 ^@ Function ^@ Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. http://togogenome.org/gene/7962:myog ^@ http://purl.uniprot.org/uniprot/A0A8C2GY17 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:LOC109068887 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6N4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Endoplasmic reticulum membrane|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109052600 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLD5 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109079890 ^@ http://purl.uniprot.org/uniprot/A0A8C1KWK9 ^@ Caution|||Similarity ^@ Belongs to the sclerostin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109059111 ^@ http://purl.uniprot.org/uniprot/A0A8C2EA15 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/7962:LOC109088903 ^@ http://purl.uniprot.org/uniprot/A0A8C2I7R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/7962:LOC109071910 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIN9 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109106603 ^@ http://purl.uniprot.org/uniprot/A0A8C1UMX1 ^@ Similarity ^@ Belongs to the Churchill family. http://togogenome.org/gene/7962:LOC109047333 ^@ http://purl.uniprot.org/uniprot/A0A8C1KK57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/7962:LOC109087140 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRI9 ^@ Similarity ^@ Belongs to the ENTREP family. http://togogenome.org/gene/7962:LOC109049636 ^@ http://purl.uniprot.org/uniprot/A0A8C2GCF9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109109327 ^@ http://purl.uniprot.org/uniprot/A0A8C1A3F1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pym family.|||Cytoplasm|||Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex. http://togogenome.org/gene/7962:LOC109063948 ^@ http://purl.uniprot.org/uniprot/A0A8C1GA94 ^@ Similarity ^@ Belongs to the ANKRD34 family. http://togogenome.org/gene/7962:ecrg4b ^@ http://purl.uniprot.org/uniprot/A0A8C1GZ40 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the augurin family.|||Cytoplasm|||Membrane|||Secreted http://togogenome.org/gene/7962:LOC122133854 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEA2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109076104 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y0Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPACA4/bouncer family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109067532 ^@ http://purl.uniprot.org/uniprot/A0A8C1RQW1 ^@ Similarity ^@ Belongs to the palmitoyl-protein thioesterase family. http://togogenome.org/gene/7962:LOC109096771 ^@ http://purl.uniprot.org/uniprot/A0A8C1CQV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the translin family.|||DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.|||Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.|||Nucleus|||Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring. http://togogenome.org/gene/7962:zgc:92591 ^@ http://purl.uniprot.org/uniprot/A0A8C2HAF6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109049930 ^@ http://purl.uniprot.org/uniprot/A0A8C1GB39 ^@ Similarity ^@ Belongs to the peptidase M50A family. http://togogenome.org/gene/7962:LOC109080869 ^@ http://purl.uniprot.org/uniprot/A0A8C1KA20 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:slc35d1a ^@ http://purl.uniprot.org/uniprot/A0A8C1HBA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109110779 ^@ http://purl.uniprot.org/uniprot/A0A8C1UWW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylin family.|||Secreted http://togogenome.org/gene/7962:LOC109108788 ^@ http://purl.uniprot.org/uniprot/A0A8C1C202 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA12 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109108599 ^@ http://purl.uniprot.org/uniprot/A0A1S7IX42 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109057693 ^@ http://purl.uniprot.org/uniprot/A0A8C1U8C9 ^@ Function|||Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). http://togogenome.org/gene/7962:LOC109091291 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/7962:fam98b ^@ http://purl.uniprot.org/uniprot/A0A8C1H0J7 ^@ Similarity ^@ Belongs to the FAM98 family. http://togogenome.org/gene/7962:LOC109047034 ^@ http://purl.uniprot.org/uniprot/A0A8C1IUC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Membrane|||cytosol http://togogenome.org/gene/7962:LOC109095158 ^@ http://purl.uniprot.org/uniprot/A0A8C1H2R7 ^@ Function|||Similarity ^@ Belongs to the rod/cone cGMP-PDE gamma subunit family.|||Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones. http://togogenome.org/gene/7962:LOC109098516 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MiT/TFE family.|||Nucleus http://togogenome.org/gene/7962:LOC109102406 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y8F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the EF-1-beta/EF-1-delta family.|||EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.|||EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. http://togogenome.org/gene/7962:LOC109060437 ^@ http://purl.uniprot.org/uniprot/A0A8C1FXZ9 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:rpl29 ^@ http://purl.uniprot.org/uniprot/A0A8C1RIG5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL29 family. http://togogenome.org/gene/7962:acp5b ^@ http://purl.uniprot.org/uniprot/A0A8C1FF15 ^@ Cofactor ^@ Binds 2 iron ions per subunit. http://togogenome.org/gene/7962:LOC109085246 ^@ http://purl.uniprot.org/uniprot/A0A8C1F3X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:LOC109054309 ^@ http://purl.uniprot.org/uniprot/A0A8C1K4F4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:arl1 ^@ http://purl.uniprot.org/uniprot/A0A8C1UNR3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:LOC109061875 ^@ http://purl.uniprot.org/uniprot/A0A8C1SEG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.|||Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.|||Membrane|||This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. http://togogenome.org/gene/7962:LOC109102218 ^@ http://purl.uniprot.org/uniprot/A0A8C1XBT5 ^@ Function|||Similarity ^@ Belongs to the calcitonin family.|||Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. http://togogenome.org/gene/7962:insl5a ^@ http://purl.uniprot.org/uniprot/A0A8C2L674 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109059357 ^@ http://purl.uniprot.org/uniprot/A0A8C1TRZ1 ^@ Function|||Similarity ^@ Belongs to the SPSB family.|||May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/7962:LOC109047054 ^@ http://purl.uniprot.org/uniprot/A5LG08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109107136 ^@ http://purl.uniprot.org/uniprot/A0A8C1XR69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109051818 ^@ http://purl.uniprot.org/uniprot/A0A8C1M8F6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109077167 ^@ http://purl.uniprot.org/uniprot/A0A220NYU9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109048999 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZH6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:golt1bb ^@ http://purl.uniprot.org/uniprot/A0A8C1D9W5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||May be involved in fusion of ER-derived transport vesicles with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:plbd1a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y904 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/7962:LOC109095279 ^@ http://purl.uniprot.org/uniprot/A0A8C1B194 ^@ Similarity ^@ Belongs to the PPDPF family. http://togogenome.org/gene/7962:LOC109104606 ^@ http://purl.uniprot.org/uniprot/A0A8C1CS00 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109048595 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109058585 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA01 ^@ Similarity ^@ Belongs to the cystatin family. http://togogenome.org/gene/7962:LOC109084446 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109058693 ^@ http://purl.uniprot.org/uniprot/A0A8C2D893 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109111501 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q1Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:zgc:153990 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:ppp4cb ^@ http://purl.uniprot.org/uniprot/A0A8C1B4Z9 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7962:LOC109075440 ^@ http://purl.uniprot.org/uniprot/A0A8C2K7S5 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:csrnp1a ^@ http://purl.uniprot.org/uniprot/A0A8C1F936 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AXUD1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109103838 ^@ http://purl.uniprot.org/uniprot/A0A8C1BKJ9 ^@ Function|||Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). http://togogenome.org/gene/7962:LOC109097728 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGW3 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109092128 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/7962:LOC109096998 ^@ http://purl.uniprot.org/uniprot/Q8UUS2 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109046690 ^@ http://purl.uniprot.org/uniprot/A0A8C1ASC7 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:LOC109097495 ^@ http://purl.uniprot.org/uniprot/A0A8C2KPA4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ERG2 family.|||Cytoplasmic vesicle|||Endoplasmic reticulum membrane|||Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.|||Homotrimer.|||Membrane|||Nucleus envelope|||Nucleus inner membrane|||Nucleus outer membrane|||The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.|||Vesicle http://togogenome.org/gene/7962:LOC109084248 ^@ http://purl.uniprot.org/uniprot/A0A8C1IFX7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109112740 ^@ http://purl.uniprot.org/uniprot/A0A8C1RNH4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109094250 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:irf2bp2a ^@ http://purl.uniprot.org/uniprot/A0A8C1JPD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF2BP family.|||Nucleus http://togogenome.org/gene/7962:LOC109045646 ^@ http://purl.uniprot.org/uniprot/A0A8C0YR17 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109083199 ^@ http://purl.uniprot.org/uniprot/A0A8C1FEW4 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/7962:dkk3b ^@ http://purl.uniprot.org/uniprot/A0A8C1JEA5 ^@ Similarity ^@ Belongs to the dickkopf family. http://togogenome.org/gene/7962:apoea ^@ http://purl.uniprot.org/uniprot/A0A8C0YR53 ^@ Similarity ^@ Belongs to the apolipoprotein A1/A4/E family. http://togogenome.org/gene/7962:LOC109057173 ^@ http://purl.uniprot.org/uniprot/A0A8C1ED57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EXO84 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|||growth cone|||perinuclear region http://togogenome.org/gene/7962:LOC109056593 ^@ http://purl.uniprot.org/uniprot/A0A8C2JYB1|||http://purl.uniprot.org/uniprot/A0A8C2JYI4 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/7962:LOC109048103 ^@ http://purl.uniprot.org/uniprot/A0A8C1X8H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm http://togogenome.org/gene/7962:tmem98 ^@ http://purl.uniprot.org/uniprot/A0A8C1X9W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM98 family.|||Endoplasmic reticulum membrane|||Membrane|||extracellular exosome http://togogenome.org/gene/7962:slc50a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Membrane http://togogenome.org/gene/7962:LOC109052807 ^@ http://purl.uniprot.org/uniprot/A0A8C1C370 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL43 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109051326 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMF8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:alg10 ^@ http://purl.uniprot.org/uniprot/A0A8C0XT44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG10 glucosyltransferase family.|||Membrane http://togogenome.org/gene/7962:tcn2 ^@ http://purl.uniprot.org/uniprot/A0A8C1DC80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic cobalamin transport proteins family.|||Secreted http://togogenome.org/gene/7962:LOC109097010 ^@ http://purl.uniprot.org/uniprot/A0A8C2I041 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Membrane|||Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. http://togogenome.org/gene/7962:btg4 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y379 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109073656 ^@ http://purl.uniprot.org/uniprot/A0A8C1HF33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OST4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109086351 ^@ http://purl.uniprot.org/uniprot/A0A8C1B187 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109075261 ^@ http://purl.uniprot.org/uniprot/A0A8C1CQL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sprouty family.|||Cytoplasm|||Membrane http://togogenome.org/gene/7962:LOC109061570 ^@ http://purl.uniprot.org/uniprot/A0A8C1WX28 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/7962:LOC109111345 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z7E3 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:irf3 ^@ http://purl.uniprot.org/uniprot/A0A8C1LBN6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109104053 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actinoporin family. Sea anemone subfamily.|||Cell membrane|||Membrane|||Nematocyst|||Target cell membrane http://togogenome.org/gene/7962:LOC109097751 ^@ http://purl.uniprot.org/uniprot/A0A8C1K0U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.|||Nucleus http://togogenome.org/gene/7962:LOC109076976 ^@ http://purl.uniprot.org/uniprot/A0A8C2IVU4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:pabir2 ^@ http://purl.uniprot.org/uniprot/A0A8C2D6Z7 ^@ Similarity ^@ Belongs to the FAM122 family. http://togogenome.org/gene/7962:slc25a3b ^@ http://purl.uniprot.org/uniprot/A0A8C1BLS2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Interacts with PPIF; the interaction is impaired by CsA.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109072924 ^@ http://purl.uniprot.org/uniprot/A0A8C1D9J2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.|||Binds 2 magnesium ions per subunit.|||Nucleus http://togogenome.org/gene/7962:LOC109049122 ^@ http://purl.uniprot.org/uniprot/A0A8C1AI95 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109086862 ^@ http://purl.uniprot.org/uniprot/A0A8C1EBI4 ^@ Similarity ^@ Belongs to the PRPH2/ROM1 family. http://togogenome.org/gene/7962:LOC109076278 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:lamp1b ^@ http://purl.uniprot.org/uniprot/A0A8C1B0S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/7962:LOC109105107 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXV7 ^@ Subcellular Location Annotation ^@ Membrane|||chromaffin granule membrane http://togogenome.org/gene/7962:tshba ^@ http://purl.uniprot.org/uniprot/O13051 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/7962:LOC109059654 ^@ http://purl.uniprot.org/uniprot/A0A8C1QC44 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109105569 ^@ http://purl.uniprot.org/uniprot/A0A8C0YWB8 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109103168 ^@ http://purl.uniprot.org/uniprot/A0A8C1L6X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/7962:LOC109070586 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:rtn1a ^@ http://purl.uniprot.org/uniprot/A0A8C1SKJ6|||http://purl.uniprot.org/uniprot/A0A8C2F323 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:golm2 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLM family.|||Membrane http://togogenome.org/gene/7962:LOC109050385 ^@ http://purl.uniprot.org/uniprot/A0A8C1C4C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the neuromedin-U and neuromedin-S neuropeptides. http://togogenome.org/gene/7962:LOC109083123 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZRL0 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/7962:srxn1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EUW2 ^@ Similarity ^@ Belongs to the sulfiredoxin family. http://togogenome.org/gene/7962:LOC109059833 ^@ http://purl.uniprot.org/uniprot/A0A8C1LV48 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/7962:LOC109103108 ^@ http://purl.uniprot.org/uniprot/A0A8C1GSU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109057822 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEV1 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/7962:LOC109102600 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109093477 ^@ http://purl.uniprot.org/uniprot/A0A8C2GES8 ^@ Similarity ^@ Belongs to the BACURD family. http://togogenome.org/gene/7962:LOC109062560 ^@ http://purl.uniprot.org/uniprot/A0A0K2RVS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109049692 ^@ http://purl.uniprot.org/uniprot/A0A8C1R0R4 ^@ Similarity ^@ Belongs to the GST superfamily. Theta family. http://togogenome.org/gene/7962:LOC109100183 ^@ http://purl.uniprot.org/uniprot/A0A8C1GB54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109095928 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109060473 ^@ http://purl.uniprot.org/uniprot/A0A8C1DD95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109061576 ^@ http://purl.uniprot.org/uniprot/A0A8C1GNJ8 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/7962:LOC109100783 ^@ http://purl.uniprot.org/uniprot/A0A8C1ARM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/7962:LOC109079388 ^@ http://purl.uniprot.org/uniprot/A0A8C1CY06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIII family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109054619 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAR6 family.|||Cytoplasm|||tight junction http://togogenome.org/gene/7962:LOC109095361 ^@ http://purl.uniprot.org/uniprot/A0A8C1BTI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109055169 ^@ http://purl.uniprot.org/uniprot/A0A8C2AJ11 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/7962:LOC109086141 ^@ http://purl.uniprot.org/uniprot/A0A8C1NI29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).|||Nucleus http://togogenome.org/gene/7962:LOC109047790 ^@ http://purl.uniprot.org/uniprot/A0A8C1AH15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109077219 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MNS1 family.|||Nucleus|||cilium axoneme|||flagellum axoneme http://togogenome.org/gene/7962:LOC109099065 ^@ http://purl.uniprot.org/uniprot/A0A8C1PXJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109049840 ^@ http://purl.uniprot.org/uniprot/A0A8C1BZ67 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase family.|||Homodimer. http://togogenome.org/gene/7962:LOC109110095 ^@ http://purl.uniprot.org/uniprot/A0A8C1J3R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/7962:LOC109109685 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.|||Membrane http://togogenome.org/gene/7962:LOC109104649 ^@ http://purl.uniprot.org/uniprot/P70073 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109078118 ^@ http://purl.uniprot.org/uniprot/A0A8C1FBX9 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:ccr12a ^@ http://purl.uniprot.org/uniprot/A0A8C1CN14 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109078077 ^@ http://purl.uniprot.org/uniprot/A0A8C1FG71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/7962:snf8 ^@ http://purl.uniprot.org/uniprot/A0A8C2K1Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF8 family.|||Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II). http://togogenome.org/gene/7962:LOC109091880 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family. GDNF subfamily.|||Secreted http://togogenome.org/gene/7962:atf4b ^@ http://purl.uniprot.org/uniprot/A0A8C1MS80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Nucleus http://togogenome.org/gene/7962:LOC109105044 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4I9 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin E subfamily. http://togogenome.org/gene/7962:LOC109056676 ^@ http://purl.uniprot.org/uniprot/A0A8C1IKR7 ^@ Function|||Similarity ^@ Belongs to the cytochrome c oxidase subunit 6B.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. http://togogenome.org/gene/7962:aph1b ^@ http://purl.uniprot.org/uniprot/A0A8C1A5F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the APH-1 family.|||Component of the gamma-secretase complex.|||Membrane|||Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors. http://togogenome.org/gene/7962:LOC109093913 ^@ http://purl.uniprot.org/uniprot/A0A0D3QEP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.|||cytoskeleton http://togogenome.org/gene/7962:rnaseh2a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y5R8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family. Eukaryotic subfamily.|||Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/7962:mul1b ^@ http://purl.uniprot.org/uniprot/A0A8C0YJ86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC122134040 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZHX family.|||Nucleus http://togogenome.org/gene/7962:LOC109107342 ^@ http://purl.uniprot.org/uniprot/A0A8C1L4B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 6c family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109079040 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5L3 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:ccr9a ^@ http://purl.uniprot.org/uniprot/A0A8C1UP76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/7962:LOC109049094 ^@ http://purl.uniprot.org/uniprot/A0A8C0YPN4 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7962:LOC109046368 ^@ http://purl.uniprot.org/uniprot/A0A8C1NN62 ^@ Function ^@ Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH. http://togogenome.org/gene/7962:LOC109057989 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCR10/QCR9 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109063554 ^@ http://purl.uniprot.org/uniprot/A0A8C1E8R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/7962:LOC109106006 ^@ http://purl.uniprot.org/uniprot/A0A8C2I9S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/7962:LOC109048052 ^@ http://purl.uniprot.org/uniprot/A0A8C1G3R2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109095368 ^@ http://purl.uniprot.org/uniprot/A0A8C0YC89 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/7962:LOC109066073 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNR5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:LOC109047416 ^@ http://purl.uniprot.org/uniprot/A0A8C2B287 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109052667 ^@ http://purl.uniprot.org/uniprot/A0A8C1DY32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EGR C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109107361 ^@ http://purl.uniprot.org/uniprot/A0A8C1KFI5 ^@ Similarity ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. http://togogenome.org/gene/7962:LOC109106705 ^@ http://purl.uniprot.org/uniprot/A0A8C1AG55 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/7962:LOC109070680 ^@ http://purl.uniprot.org/uniprot/A0A8C1PQK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/7962:LOC109092396 ^@ http://purl.uniprot.org/uniprot/A0A8C1N437 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/7962:tmem129 ^@ http://purl.uniprot.org/uniprot/A0A8C1E8G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM129 family.|||Membrane http://togogenome.org/gene/7962:LOC109096796 ^@ http://purl.uniprot.org/uniprot/A0A8C1H2L2 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/7962:LOC109097483 ^@ http://purl.uniprot.org/uniprot/A0A8C1H0Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109068402 ^@ http://purl.uniprot.org/uniprot/K4N184|||http://purl.uniprot.org/uniprot/K4NCJ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109083476 ^@ http://purl.uniprot.org/uniprot/A0A8C1HLQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucose-6-phosphatase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109083354 ^@ http://purl.uniprot.org/uniprot/A0A8C1A122 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM163 family.|||Early endosome membrane|||Endosome membrane|||May bind zinc and other divalent cations and recruit them to vesicular organelles.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/7962:ywhabl ^@ http://purl.uniprot.org/uniprot/A0A8C2CDQ7 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:LOC109049794 ^@ http://purl.uniprot.org/uniprot/A0A8C1H294 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109057088 ^@ http://purl.uniprot.org/uniprot/A0A8C1DP84|||http://purl.uniprot.org/uniprot/A0A8C1HPP8 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109049147 ^@ http://purl.uniprot.org/uniprot/A0A8C1B8Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109066524 ^@ http://purl.uniprot.org/uniprot/A0A8C1JYT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 6c family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109075702 ^@ http://purl.uniprot.org/uniprot/A0A1B4ZD99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109100118 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQR0 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109053141 ^@ http://purl.uniprot.org/uniprot/A0A8C1TQ94|||http://purl.uniprot.org/uniprot/A0A8C2HI86 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109079487 ^@ http://purl.uniprot.org/uniprot/A0A8C1FB54 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/7962:LOC109048157 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109049923 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVX8 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:tatdn3 ^@ http://purl.uniprot.org/uniprot/A0A8C2B3R6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/7962:LOC109052109 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFD1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109088966 ^@ http://purl.uniprot.org/uniprot/A0A8C1FZH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109095281 ^@ http://purl.uniprot.org/uniprot/A0A8C1PTI9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:tmem59 ^@ http://purl.uniprot.org/uniprot/A0A8C1EB64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:spns3 ^@ http://purl.uniprot.org/uniprot/A0A8C1FLC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/7962:ube2b ^@ http://purl.uniprot.org/uniprot/A0A8C1B574 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109084515 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZ96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DPM2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum membrane|||Membrane|||Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. http://togogenome.org/gene/7962:LOC109059519 ^@ http://purl.uniprot.org/uniprot/A0A8C1HNS7 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:tgm1l3 ^@ http://purl.uniprot.org/uniprot/A0A8C1H822 ^@ Cofactor|||Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family.|||Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/7962:LOC109105970 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQL9 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:LOC109061389 ^@ http://purl.uniprot.org/uniprot/A0A8C2E4B8 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/7962:LOC109071060 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2Y9 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/7962:LOC109046185 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:spns2 ^@ http://purl.uniprot.org/uniprot/A0A8C2A8S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/7962:LOC109063978 ^@ http://purl.uniprot.org/uniprot/A0A8C1B7S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/7962:LOC109050063 ^@ http://purl.uniprot.org/uniprot/A0A8C1EA97 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109053003 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/7962:snx18a ^@ http://purl.uniprot.org/uniprot/A0A8C1DWC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasmic vesicle membrane http://togogenome.org/gene/7962:LOC109059878 ^@ http://purl.uniprot.org/uniprot/A0A8C1FN06 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109064893 ^@ http://purl.uniprot.org/uniprot/A0A8C1FUU8 ^@ Similarity ^@ Belongs to the angiomotin family. http://togogenome.org/gene/7962:il12ba ^@ http://purl.uniprot.org/uniprot/A0A8C1DE82 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IL-12B family.|||Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.|||Secreted http://togogenome.org/gene/7962:ccdc86 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNS0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109067092 ^@ http://purl.uniprot.org/uniprot/A0A8C1XY56 ^@ Function|||Similarity ^@ Belongs to the globin family.|||Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. http://togogenome.org/gene/7962:LOC109091704 ^@ http://purl.uniprot.org/uniprot/A0A8C1CC34 ^@ Function|||Similarity ^@ Belongs to the MEIG1 family.|||Essential for spermiogenesis. http://togogenome.org/gene/7962:LOC109104741 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y802 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Binds equally well IGF1 and IGF2.|||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109054584 ^@ http://purl.uniprot.org/uniprot/A0A8C1JGZ8 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109055222 ^@ http://purl.uniprot.org/uniprot/A0A8C2CGM5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109073468 ^@ http://purl.uniprot.org/uniprot/A0A8C1FF54 ^@ Similarity ^@ Belongs to the PPP1R15 family. http://togogenome.org/gene/7962:tlcd5b ^@ http://purl.uniprot.org/uniprot/A0A8C2GK83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:marcksa ^@ http://purl.uniprot.org/uniprot/A0A8C1HPT9 ^@ Similarity ^@ Belongs to the MARCKS family. http://togogenome.org/gene/7962:LOC109089057 ^@ http://purl.uniprot.org/uniprot/A0A8C1QQ14 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109102138 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan that bears heparan sulfate. http://togogenome.org/gene/7962:LOC109064350 ^@ http://purl.uniprot.org/uniprot/A0A8C1TM70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cleavage furrow|||Cytoplasmic vesicle membrane|||Early endosome membrane|||Endoplasmic reticulum membrane|||Endosome membrane|||neuron projection|||trans-Golgi network http://togogenome.org/gene/7962:LOC109052712 ^@ http://purl.uniprot.org/uniprot/A0A8C1JX76 ^@ Similarity ^@ Belongs to the BLCAP family. http://togogenome.org/gene/7962:LOC109053342 ^@ http://purl.uniprot.org/uniprot/A0A8C1A924 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109098441 ^@ http://purl.uniprot.org/uniprot/A0A8C0YW95|||http://purl.uniprot.org/uniprot/A0A8C1A6N1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109088861 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0M3 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/7962:LOC109072253 ^@ http://purl.uniprot.org/uniprot/A0A8C2J2E9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109052013 ^@ http://purl.uniprot.org/uniprot/A0A8C1CU57 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/7962:LOC109096927 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/7962:LOC109106806 ^@ http://purl.uniprot.org/uniprot/A0A8C1G007 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109111583 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109105104 ^@ http://purl.uniprot.org/uniprot/A0A8C1H4Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109052522 ^@ http://purl.uniprot.org/uniprot/A0A8C0YB71 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109097894 ^@ http://purl.uniprot.org/uniprot/A0A8C1AW48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109090400 ^@ http://purl.uniprot.org/uniprot/A0A8C1JYX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Endoplasmic reticulum lumen http://togogenome.org/gene/7962:LOC109113637 ^@ http://purl.uniprot.org/uniprot/A0A8C1E3Y8 ^@ Similarity ^@ Belongs to the LAPTM4/LAPTM5 transporter family. http://togogenome.org/gene/7962:LOC109069229 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJP1 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109110295 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBM8 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/7962:mvb12a ^@ http://purl.uniprot.org/uniprot/A0A8C1F279 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MVB12 family.|||Endosome membrane|||Late endosome membrane|||Membrane http://togogenome.org/gene/7962:mrpl10 ^@ http://purl.uniprot.org/uniprot/A0A8C1HIB5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/7962:LOC109060894 ^@ http://purl.uniprot.org/uniprot/A0A8C1SS61 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/7962:vkorc1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HI89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:arf2a ^@ http://purl.uniprot.org/uniprot/A0A8C1XY66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:bloc1s5 ^@ http://purl.uniprot.org/uniprot/A0A8C1RU79 ^@ Function|||Similarity ^@ Belongs to the BLOC1S5 family.|||Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). http://togogenome.org/gene/7962:nxph1 ^@ http://purl.uniprot.org/uniprot/A0A8C1W6P3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexophilin family.|||May be signaling molecules that resemble neuropeptides.|||Secreted http://togogenome.org/gene/7962:map1lc3a ^@ http://purl.uniprot.org/uniprot/A0A8C1SS50 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109111724 ^@ http://purl.uniprot.org/uniprot/A0A8C1P1T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CART family.|||Secreted http://togogenome.org/gene/7962:LOC109103176 ^@ http://purl.uniprot.org/uniprot/A0A8C1C8J2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109054307 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFR7 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:arpc4 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Cell projection|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||cytoskeleton http://togogenome.org/gene/7962:LOC109071334 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKY2 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/7962:LOC109056122 ^@ http://purl.uniprot.org/uniprot/A0A8C1BM24 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/7962:cdkn1ba ^@ http://purl.uniprot.org/uniprot/A0A8C2ETE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDI family.|||Cytoplasm|||Endosome|||Nucleus http://togogenome.org/gene/7962:nog5 ^@ http://purl.uniprot.org/uniprot/A0A8C1QXM3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the noggin family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:LOC109100567 ^@ http://purl.uniprot.org/uniprot/A0A8C1H4W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Vesicular transporter family.|||Membrane http://togogenome.org/gene/7962:LOC109078963 ^@ http://purl.uniprot.org/uniprot/A0A8C1L5F8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).|||Nucleus http://togogenome.org/gene/7962:LOC109101476 ^@ http://purl.uniprot.org/uniprot/A0A8C2PV33 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:cyyr1 ^@ http://purl.uniprot.org/uniprot/A0A8C2PY76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYYR1 family.|||Membrane http://togogenome.org/gene/7962:LOC109065732 ^@ http://purl.uniprot.org/uniprot/A0A8C2HMV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109054976 ^@ http://purl.uniprot.org/uniprot/A0A8C1V0W8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109066304 ^@ http://purl.uniprot.org/uniprot/A0A8C1THW7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/7962:LOC109053713 ^@ http://purl.uniprot.org/uniprot/Q804C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GnRH family.|||Secreted|||Stimulates the secretion of gonadotropins. http://togogenome.org/gene/7962:fam32a ^@ http://purl.uniprot.org/uniprot/A0A8C1GS09 ^@ Similarity ^@ Belongs to the FAM32 family. http://togogenome.org/gene/7962:LOC109060247 ^@ http://purl.uniprot.org/uniprot/A0A8C1ED35 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/7962:KEF38_p06 ^@ http://purl.uniprot.org/uniprot/P24974|||http://purl.uniprot.org/uniprot/Q14F86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109091353 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1N6 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109090783 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0X6 ^@ Similarity|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer. http://togogenome.org/gene/7962:vamp5 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:LOC109067592 ^@ http://purl.uniprot.org/uniprot/A0A8C1CG55 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109104065 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5I8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ELO family. ELOVL4 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane|||Oligomer.|||The C-terminal di-lysine motif may confer endoplasmic reticulum localization. http://togogenome.org/gene/7962:LOC109101076 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUK9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Homodimer.|||Mitochondrion outer membrane|||Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. http://togogenome.org/gene/7962:LOC109091375 ^@ http://purl.uniprot.org/uniprot/A0A8C1KVF6|||http://purl.uniprot.org/uniprot/A0A8C1KXR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/7962:LOC109067155 ^@ http://purl.uniprot.org/uniprot/A0A8C1EHT8 ^@ Similarity ^@ Belongs to the pleiotrophin family. http://togogenome.org/gene/7962:atpsckmt ^@ http://purl.uniprot.org/uniprot/A0A8C1FSY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109103775 ^@ http://purl.uniprot.org/uniprot/A0A8C1C2I8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109111282 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109085009 ^@ http://purl.uniprot.org/uniprot/A0A8C2I990 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/7962:atl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1PZ14 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. http://togogenome.org/gene/7962:LOC109047286 ^@ http://purl.uniprot.org/uniprot/A0A8C1H0K3 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/7962:psme2 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERN8 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/7962:LOC109067994 ^@ http://purl.uniprot.org/uniprot/A0A8C1CKN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109085501 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3E9 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:pih1d1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C0N3 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/7962:LOC109112193 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXY9 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/7962:spi1a ^@ http://purl.uniprot.org/uniprot/A0A8C1ME59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109107021 ^@ http://purl.uniprot.org/uniprot/A0A8C1G3K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:tmem150ab ^@ http://purl.uniprot.org/uniprot/A0A8C1B8S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRAM/TMEM150 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109092169 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANP8 ^@ Similarity ^@ Belongs to the dynein intermediate chain family. http://togogenome.org/gene/7962:LOC109101449 ^@ http://purl.uniprot.org/uniprot/A0A8C1QTC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the immunoglobulin superfamily.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC109087901 ^@ http://purl.uniprot.org/uniprot/A0A8C1JJ20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/7962:adtrp1 ^@ http://purl.uniprot.org/uniprot/A0A8C2CVN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIG1 family.|||Membrane http://togogenome.org/gene/7962:LOC109074333 ^@ http://purl.uniprot.org/uniprot/A0A8C1FT80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AVIT (prokineticin) family.|||Secreted http://togogenome.org/gene/7962:LOC109060482 ^@ http://purl.uniprot.org/uniprot/A0A8C1U261 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sestrin family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109090568 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0F8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC122133937 ^@ http://purl.uniprot.org/uniprot/A0A8C2D4U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 10 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109079483 ^@ http://purl.uniprot.org/uniprot/A0A8C1EY03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/7962:LOC109102488 ^@ http://purl.uniprot.org/uniprot/A0A8C1AEZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.|||Chromosome|||Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.|||Nucleus http://togogenome.org/gene/7962:LOC109063464 ^@ http://purl.uniprot.org/uniprot/A0A8C1E6G1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:dph2 ^@ http://purl.uniprot.org/uniprot/A0A8C1HWJ2 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH2 subfamily.|||Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit. http://togogenome.org/gene/7962:ugcg ^@ http://purl.uniprot.org/uniprot/A0A8C1H1P5 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/7962:LOC109087573 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parvin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109109176 ^@ http://purl.uniprot.org/uniprot/A0A0C6EMI7 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:dedd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5L9 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109108799 ^@ http://purl.uniprot.org/uniprot/A0A8C1C135|||http://purl.uniprot.org/uniprot/Q5ZP81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109058062 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ECSIT family.|||Cytoplasm|||Mitochondrion|||Nucleus http://togogenome.org/gene/7962:KEF38_p08 ^@ http://purl.uniprot.org/uniprot/P24946 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:tefb ^@ http://purl.uniprot.org/uniprot/A0A8C1N9Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. PAR subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109060891 ^@ http://purl.uniprot.org/uniprot/A0A8C2GYP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:si:ch211-260e23.9 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLB7 ^@ Subcellular Location Annotation ^@ PML body|||autophagosome|||cytosol http://togogenome.org/gene/7962:LOC109071263 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the meteorin family.|||Secreted http://togogenome.org/gene/7962:LOC109091333 ^@ http://purl.uniprot.org/uniprot/A0A8C2PZA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109064251 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109111680 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q8X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphatidyl serine synthase family.|||Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:brk1 ^@ http://purl.uniprot.org/uniprot/A0A8C1W3W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRK1 family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109054155 ^@ http://purl.uniprot.org/uniprot/A0A8C1SWJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SIX/Sine oculis homeobox family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:esr1 ^@ http://purl.uniprot.org/uniprot/A0A8C1A560 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Binds DNA as a homodimer. Can form a heterodimer with ER-beta.|||Nucleus|||The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. http://togogenome.org/gene/7962:LOC109105985 ^@ http://purl.uniprot.org/uniprot/A0A8C2A936 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/7962:LOC109093467 ^@ http://purl.uniprot.org/uniprot/A0A6C0MA32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. C/EBP subfamily.|||Nucleus http://togogenome.org/gene/7962:rpl12 ^@ http://purl.uniprot.org/uniprot/A0A8C1YQU8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/7962:LOC109069274 ^@ http://purl.uniprot.org/uniprot/A0A8C2I4N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/7962:LOC109087306 ^@ http://purl.uniprot.org/uniprot/A0A8C1LYM9 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/7962:LOC109045365 ^@ http://purl.uniprot.org/uniprot/A0A8C1HND0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:LOC109109173 ^@ http://purl.uniprot.org/uniprot/A0A8C2DMN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:gadd45ga ^@ http://purl.uniprot.org/uniprot/A0A8C2BCA1 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109084977 ^@ http://purl.uniprot.org/uniprot/A0A8C1BMF6 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/7962:LOC109095595 ^@ http://purl.uniprot.org/uniprot/A0A8C2L0M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:med8 ^@ http://purl.uniprot.org/uniprot/A0A8C1FZW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 8 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109073385 ^@ http://purl.uniprot.org/uniprot/A9LRY8 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/7962:c1d ^@ http://purl.uniprot.org/uniprot/A0A8C0YR83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the C1D family.|||Cytoplasm|||Monomer and homodimer.|||Nucleus|||Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.|||nucleolus http://togogenome.org/gene/7962:LOC109113750 ^@ http://purl.uniprot.org/uniprot/A0A8C1JZX8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109049224 ^@ http://purl.uniprot.org/uniprot/A0A8C1AT68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/7962:nsg2 ^@ http://purl.uniprot.org/uniprot/A0A8C1D9J5 ^@ Similarity ^@ Belongs to the NSG family. http://togogenome.org/gene/7962:LOC109111634 ^@ http://purl.uniprot.org/uniprot/A0A8C1W7F3 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109067732 ^@ http://purl.uniprot.org/uniprot/A0A8C1J4R4 ^@ Similarity ^@ Belongs to the PHYHIP family. http://togogenome.org/gene/7962:LOC109047209 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109054790 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109066068 ^@ http://purl.uniprot.org/uniprot/A0A8C2C0H9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109055907 ^@ http://purl.uniprot.org/uniprot/A0A8C2E5P4 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109104642 ^@ http://purl.uniprot.org/uniprot/A0A8C1CY55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109049068 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZKM1 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109104995 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PNRC family. PNRC2 subfamily.|||Nucleus|||P-body http://togogenome.org/gene/7962:LOC109113310 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQK9|||http://purl.uniprot.org/uniprot/A0A8C1BT94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109064292 ^@ http://purl.uniprot.org/uniprot/A0A8C1DUN9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.|||Cytoplasm http://togogenome.org/gene/7962:LOC109048585 ^@ http://purl.uniprot.org/uniprot/A0A8C1YJV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109086930 ^@ http://purl.uniprot.org/uniprot/A0A8C1P0S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109077338 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZG1 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/7962:actc1a ^@ http://purl.uniprot.org/uniprot/A0A8C1D5B4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:arsia ^@ http://purl.uniprot.org/uniprot/A0A8C1FHP2 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/7962:LOC109099506 ^@ http://purl.uniprot.org/uniprot/A0A8C1H9S3|||http://purl.uniprot.org/uniprot/A0A8C1TLQ8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109064307 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7962:LOC109078356 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHR5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109058010 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD3Z/FCER1G family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109056331 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWN2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109077242 ^@ http://purl.uniprot.org/uniprot/A0A8C1XGP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109064291 ^@ http://purl.uniprot.org/uniprot/A0A8C1HP28 ^@ Similarity ^@ Belongs to the glycosyltransferase 25 family. http://togogenome.org/gene/7962:LOC109089265 ^@ http://purl.uniprot.org/uniprot/M4QSS5 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:ndufa6 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I LYR family.|||Mammalian complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:npy ^@ http://purl.uniprot.org/uniprot/A0A8C2JKG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPY family.|||Secreted http://togogenome.org/gene/7962:arrdc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1GTV2|||http://purl.uniprot.org/uniprot/A0A8C1GU68 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:tmem237a ^@ http://purl.uniprot.org/uniprot/A0A8C0YAX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM237 family.|||Component of the transition zone in primary cilia. Required for ciliogenesis.|||Membrane|||cilium http://togogenome.org/gene/7962:LOC109060828 ^@ http://purl.uniprot.org/uniprot/A0A8C1B172 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109091802 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFK8|||http://purl.uniprot.org/uniprot/A0A8C1BGD8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:tmem151ba ^@ http://purl.uniprot.org/uniprot/A0A8C1ARW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM151 family.|||Membrane http://togogenome.org/gene/7962:anxa4 ^@ http://purl.uniprot.org/uniprot/A0A8C1AA60 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family.|||Zymogen granule membrane http://togogenome.org/gene/7962:utp23 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1F4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109069332 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q691 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109105665 ^@ http://purl.uniprot.org/uniprot/A0A8C1HVV2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily. http://togogenome.org/gene/7962:psd2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FLV7 ^@ Subcellular Location Annotation ^@ ruffle membrane http://togogenome.org/gene/7962:LOC109057000 ^@ http://purl.uniprot.org/uniprot/A0A8C2EWB8 ^@ Similarity ^@ Belongs to the SPARC family. http://togogenome.org/gene/7962:LOC109060670 ^@ http://purl.uniprot.org/uniprot/A0A8C1QMD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109046055 ^@ http://purl.uniprot.org/uniprot/A0A8C2JMG9 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/7962:LOC109110749 ^@ http://purl.uniprot.org/uniprot/A0A8C1QE97 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:ugt5g2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLK3 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/7962:LOC109089060 ^@ http://purl.uniprot.org/uniprot/A0A8C1HY81 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109057990 ^@ http://purl.uniprot.org/uniprot/A0A8C1N3H4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/7962:LOC109056321 ^@ http://purl.uniprot.org/uniprot/A0A8C1TPE2 ^@ Similarity ^@ Belongs to the UPF0587 family. http://togogenome.org/gene/7962:LOC109065666 ^@ http://purl.uniprot.org/uniprot/A0A8C1FTI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the translin family.|||Nucleus http://togogenome.org/gene/7962:LOC109075506 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-2-microglobulin family.|||Secreted http://togogenome.org/gene/7962:rplp2 ^@ http://purl.uniprot.org/uniprot/A0A8C2AB17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/7962:LOC109082320 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/7962:LOC109061540 ^@ http://purl.uniprot.org/uniprot/A0A8C1EWF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109102493 ^@ http://purl.uniprot.org/uniprot/A0A8C2G6T9 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/7962:cmtm7 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y6A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109107018 ^@ http://purl.uniprot.org/uniprot/A0A8C1CUF0|||http://purl.uniprot.org/uniprot/A0A8C1CYT2|||http://purl.uniprot.org/uniprot/A0A8C1PSF2|||http://purl.uniprot.org/uniprot/A0A8C1PZ03 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/7962:LOC109066375 ^@ http://purl.uniprot.org/uniprot/A0A8C1C5S1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:mdm1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MDM1 family.|||Nucleus|||centriole http://togogenome.org/gene/7962:LOC109068348 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2B7|||http://purl.uniprot.org/uniprot/A0A8C1F2Q4 ^@ Similarity ^@ Belongs to the SPT2 family. http://togogenome.org/gene/7962:LOC109047448 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y6R7 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/7962:spire2 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the spire family.|||Cell membrane|||Cytoplasmic vesicle membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/7962:LOC109092457 ^@ http://purl.uniprot.org/uniprot/A0A8C1H4L1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.|||Secreted http://togogenome.org/gene/7962:prl ^@ http://purl.uniprot.org/uniprot/A0A8C1BN69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the somatotropin/prolactin family.|||Secreted http://togogenome.org/gene/7962:LOC109095457 ^@ http://purl.uniprot.org/uniprot/A0A8C1DU09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNF152 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109074990 ^@ http://purl.uniprot.org/uniprot/A0A8C1P447 ^@ Similarity ^@ Belongs to the sprouty family. http://togogenome.org/gene/7962:LOC109059938 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109081164 ^@ http://purl.uniprot.org/uniprot/A0A8C1CX77 ^@ Similarity ^@ Belongs to the GASK family. http://togogenome.org/gene/7962:LOC109061425 ^@ http://purl.uniprot.org/uniprot/A0A8C1CFK6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7962:LOC109059508 ^@ http://purl.uniprot.org/uniprot/A0A8C1TQR4 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Component of the large ribosomal subunit. http://togogenome.org/gene/7962:LOC109074880 ^@ http://purl.uniprot.org/uniprot/A0A8C1HEJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109069331 ^@ http://purl.uniprot.org/uniprot/A0A8C1C5L8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109063358 ^@ http://purl.uniprot.org/uniprot/A0A8C1JQY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109103824 ^@ http://purl.uniprot.org/uniprot/A0A8C1BHG8 ^@ Similarity ^@ Belongs to the GIPC family. http://togogenome.org/gene/7962:LOC109066086 ^@ http://purl.uniprot.org/uniprot/A0A8C1J1Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR1 family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109109890 ^@ http://purl.uniprot.org/uniprot/A0A8C0YJQ2 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/7962:LOC109059245 ^@ http://purl.uniprot.org/uniprot/A0A1S7IX10 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:sec61g ^@ http://purl.uniprot.org/uniprot/A0A8C2DQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109077117 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/7962:acvr2aa ^@ http://purl.uniprot.org/uniprot/A0A8C1KFR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109109273 ^@ http://purl.uniprot.org/uniprot/A0A8C1CEM8 ^@ Similarity ^@ Belongs to the dapper family. http://togogenome.org/gene/7962:LOC109054775 ^@ http://purl.uniprot.org/uniprot/A0A8C1LSJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cystinosin family.|||Membrane http://togogenome.org/gene/7962:LOC109066370 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/7962:LOC109064694 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109092371 ^@ http://purl.uniprot.org/uniprot/A0A8C1EBP7 ^@ Similarity ^@ Belongs to the NC2 beta/DR1 family. http://togogenome.org/gene/7962:LOC109111089 ^@ http://purl.uniprot.org/uniprot/A0A0C6EHN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/7962:LOC109048146 ^@ http://purl.uniprot.org/uniprot/A0A8C1B461 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:ghrl ^@ http://purl.uniprot.org/uniprot/A0A8C1G1D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the motilin family.|||Secreted http://togogenome.org/gene/7962:LOC122133967 ^@ http://purl.uniprot.org/uniprot/A0A8C1GNR2 ^@ Subcellular Location Annotation ^@ centriole|||cilium|||cis-Golgi network http://togogenome.org/gene/7962:hmgn2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGN family.|||Nucleus http://togogenome.org/gene/7962:LOC109048929 ^@ http://purl.uniprot.org/uniprot/A0A8C2EXZ6 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/7962:LOC109077437 ^@ http://purl.uniprot.org/uniprot/A0A8C1DI52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:lepa ^@ http://purl.uniprot.org/uniprot/Q0KHD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the leptin family.|||Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.|||Secreted http://togogenome.org/gene/7962:LOC109101565 ^@ http://purl.uniprot.org/uniprot/A0A8C2HS51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/7962:LOC109073220 ^@ http://purl.uniprot.org/uniprot/A0A8C1N0U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRAK1BP1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109065493 ^@ http://purl.uniprot.org/uniprot/A0A8C2BX57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109049497 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q8L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. http://togogenome.org/gene/7962:LOC109107266 ^@ http://purl.uniprot.org/uniprot/A0A8C2FG69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family. Bicoid subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109098147 ^@ http://purl.uniprot.org/uniprot/A0A8C1HBG1|||http://purl.uniprot.org/uniprot/A0A8C1V2U2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/7962:LOC109055615 ^@ http://purl.uniprot.org/uniprot/A0A8C1CN79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109104660 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y922 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109094653 ^@ http://purl.uniprot.org/uniprot/A0A8C1DCW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/7962:LOC109065953 ^@ http://purl.uniprot.org/uniprot/A0A8C1S8L3|||http://purl.uniprot.org/uniprot/A0A8C2FQ16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109070632 ^@ http://purl.uniprot.org/uniprot/A0A8C1F2V7 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/7962:tmtopsb ^@ http://purl.uniprot.org/uniprot/A0A8C1CPK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109047151 ^@ http://purl.uniprot.org/uniprot/A0A8C1A9P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/7962:LOC109097354 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109055145 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.|||extracellular matrix http://togogenome.org/gene/7962:LOC109098579 ^@ http://purl.uniprot.org/uniprot/A0A8C1PKX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:polr2eb ^@ http://purl.uniprot.org/uniprot/A0A8C1KV48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.|||Nucleus http://togogenome.org/gene/7962:LOC109076350 ^@ http://purl.uniprot.org/uniprot/A0A8C1P0T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:LOC109060789 ^@ http://purl.uniprot.org/uniprot/A0A8C1X7J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109072027 ^@ http://purl.uniprot.org/uniprot/A0A8C1NR00 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:LOC109104484 ^@ http://purl.uniprot.org/uniprot/A0A8C1QX24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/7962:LOC109076639 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2A4 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/7962:LOC109090887 ^@ http://purl.uniprot.org/uniprot/A0A0C6ESY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/7962:LOC109050799 ^@ http://purl.uniprot.org/uniprot/A0A8C2DIR4 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/7962:usb1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YEQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2H phosphoesterase superfamily. USB1 family.|||Nucleus|||Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA. http://togogenome.org/gene/7962:LOC122134153 ^@ http://purl.uniprot.org/uniprot/A0A8C1G7T2 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/7962:ca8h9orf116 ^@ http://purl.uniprot.org/uniprot/A0A8C1YCN7 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/7962:LOC109052625 ^@ http://purl.uniprot.org/uniprot/A0A8C1DL79 ^@ Similarity ^@ Belongs to the WFIKKN family. http://togogenome.org/gene/7962:LOC109099434 ^@ http://purl.uniprot.org/uniprot/A0A8C1JWN1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. PHOSPHO family. http://togogenome.org/gene/7962:LOC109094701 ^@ http://purl.uniprot.org/uniprot/A0A8C1KIQ6|||http://purl.uniprot.org/uniprot/A0A8C1ZCU7 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/7962:arf6b ^@ http://purl.uniprot.org/uniprot/A0A8C1C5F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Cell membrane|||Cleavage furrow|||Endosome membrane|||Midbody ring|||Recycling endosome membrane|||filopodium membrane|||ruffle http://togogenome.org/gene/7962:etv1 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:lhb ^@ http://purl.uniprot.org/uniprot/P01235 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycoprotein hormones subunit beta family.|||Heterodimer of an alpha and a beta chain.|||Involved in gametogenesis and steroidogenesis.|||Secreted http://togogenome.org/gene/7962:LOC109055243 ^@ http://purl.uniprot.org/uniprot/A0A8C0YGR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/7962:acyp1 ^@ http://purl.uniprot.org/uniprot/A0A8C2JLN3 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/7962:LOC109057254 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/7962:LOC109053550 ^@ http://purl.uniprot.org/uniprot/A0A8C2D5M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CART family.|||Secreted http://togogenome.org/gene/7962:scfd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1VBA3 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/7962:ppp2r3c ^@ http://purl.uniprot.org/uniprot/A0A8C1E0P2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109094170 ^@ http://purl.uniprot.org/uniprot/A0A8C2H9D2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109055831 ^@ http://purl.uniprot.org/uniprot/A0A8C1CD25|||http://purl.uniprot.org/uniprot/A0A8C2GB61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the myelin proteolipid protein family.|||Membrane http://togogenome.org/gene/7962:LOC109096770 ^@ http://purl.uniprot.org/uniprot/A0A8C1CI61 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:LOC109089216 ^@ http://purl.uniprot.org/uniprot/A0A8C1TYY7 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pentraxin family.|||Binds 2 calcium ions per subunit.|||Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109049195 ^@ http://purl.uniprot.org/uniprot/A0A8C0YC62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/7962:LOC109110204 ^@ http://purl.uniprot.org/uniprot/A0A8C1S980 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:xkrx ^@ http://purl.uniprot.org/uniprot/A0A8C1EKL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:maf1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FTN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MAF1 family.|||Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.|||Nucleus http://togogenome.org/gene/7962:LOC109077200 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109091626 ^@ http://purl.uniprot.org/uniprot/A0A8C2B2Y8 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/7962:LOC109096258 ^@ http://purl.uniprot.org/uniprot/A0A8C1B9G7|||http://purl.uniprot.org/uniprot/A0A8C1BBD2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. http://togogenome.org/gene/7962:LOC109083467 ^@ http://purl.uniprot.org/uniprot/A0A8C1DAN1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:cb7h4orf48 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1E3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109061436 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0K5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.|||Belongs to the actin family. ARP2 subfamily.|||Component of the Arp2/3 complex.|||cytoskeleton http://togogenome.org/gene/7962:LOC109106672 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3M7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P4HA family.|||Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.|||Endoplasmic reticulum lumen http://togogenome.org/gene/7962:LOC109069374 ^@ http://purl.uniprot.org/uniprot/A0A8C0XVB8 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/7962:LOC109112750 ^@ http://purl.uniprot.org/uniprot/A0A8C1KWG3 ^@ Similarity ^@ Belongs to the SMEK family. http://togogenome.org/gene/7962:si:ch73-217n20.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX05 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109085846 ^@ http://purl.uniprot.org/uniprot/A0A8C1B1F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109053058 ^@ http://purl.uniprot.org/uniprot/A0A8C1A528 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109083908 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZHQ8 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/7962:LOC109052223 ^@ http://purl.uniprot.org/uniprot/A0A8C1MJ48|||http://purl.uniprot.org/uniprot/A0A8C1MJS8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SGF11 family.|||Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).|||Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.|||Nucleus|||The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module.|||The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module. http://togogenome.org/gene/7962:LOC109108008 ^@ http://purl.uniprot.org/uniprot/A0A8C1CCA3 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Cytoplasm|||May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.|||Nucleus http://togogenome.org/gene/7962:ucmab ^@ http://purl.uniprot.org/uniprot/A0A8C1AM57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UCMA family.|||May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.|||extracellular matrix http://togogenome.org/gene/7962:LOC109103930 ^@ http://purl.uniprot.org/uniprot/A0A8C1LUE7 ^@ Similarity ^@ Belongs to the TCP11 family. http://togogenome.org/gene/7962:LOC109084863 ^@ http://purl.uniprot.org/uniprot/A0A8C1UMP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/7962:LOC109090750 ^@ http://purl.uniprot.org/uniprot/A0A8C1WMU7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109096780 ^@ http://purl.uniprot.org/uniprot/A0A8C2CM36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109058250 ^@ http://purl.uniprot.org/uniprot/A0A8C1BK79 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:got1l1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CVQ1 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/7962:kpna3 ^@ http://purl.uniprot.org/uniprot/A0A8C1B5A4 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/7962:hoxb5b ^@ http://purl.uniprot.org/uniprot/A0A8C1BY75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109068840 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0Z7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109095016 ^@ http://purl.uniprot.org/uniprot/O42315 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109113553 ^@ http://purl.uniprot.org/uniprot/A0A8C2DQA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0456 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109056202 ^@ http://purl.uniprot.org/uniprot/A0A8C1RF41 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109054590 ^@ http://purl.uniprot.org/uniprot/A0A8C1BRS2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:c9 ^@ http://purl.uniprot.org/uniprot/A0A8C1D9X1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Secreted|||Target cell membrane http://togogenome.org/gene/7962:LOC109053200 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y4U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109082242 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109107991 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNAAF3 family.|||Cytoplasm|||Dynein axonemal particle|||Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia. http://togogenome.org/gene/7962:LOC109100810 ^@ http://purl.uniprot.org/uniprot/A0A8C1JWR4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1B family.|||Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.|||Peroxisome|||The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity. http://togogenome.org/gene/7962:LOC109052446 ^@ http://purl.uniprot.org/uniprot/A0A8C1CT40 ^@ Function|||Similarity ^@ Belongs to the SAP18 family.|||Involved in the tethering of the SIN3 complex to core histone proteins. http://togogenome.org/gene/7962:ak8 ^@ http://purl.uniprot.org/uniprot/A0A8C1IEA9 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/7962:alkbh8 ^@ http://purl.uniprot.org/uniprot/A0A8C1P1J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alkB family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109053413 ^@ http://purl.uniprot.org/uniprot/A0A8C1S090 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109048032 ^@ http://purl.uniprot.org/uniprot/A0A8C1F515 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109055618 ^@ http://purl.uniprot.org/uniprot/A0A8C1RH95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:slc40a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1RSE4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in iron transport and iron homeostasis.|||Membrane http://togogenome.org/gene/7962:arf2b ^@ http://purl.uniprot.org/uniprot/A0A8C1JVV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:LOC109104650 ^@ http://purl.uniprot.org/uniprot/O13140 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:gata1a ^@ http://purl.uniprot.org/uniprot/A0A8C0YEC8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109067604 ^@ http://purl.uniprot.org/uniprot/A0A8C1MNU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM263 family.|||Membrane http://togogenome.org/gene/7962:LOC109085901 ^@ http://purl.uniprot.org/uniprot/A0A8C2E5P4 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109089781 ^@ http://purl.uniprot.org/uniprot/A0A8C1MVN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bL33 family.|||Cytoplasm http://togogenome.org/gene/7962:adra1ba ^@ http://purl.uniprot.org/uniprot/A0A8C1BN32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasm|||Membrane|||This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.|||caveola http://togogenome.org/gene/7962:LOC109056030 ^@ http://purl.uniprot.org/uniprot/A0A8C1EP90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-28 family.|||nucleolus http://togogenome.org/gene/7962:LOC109093905 ^@ http://purl.uniprot.org/uniprot/A0A8C1TDC8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:tfcp2l1 ^@ http://purl.uniprot.org/uniprot/A0A8C1PVR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the grh/CP2 family. CP2 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109084442 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG75|||http://purl.uniprot.org/uniprot/A0A8C1HU84|||http://purl.uniprot.org/uniprot/A0A8C1HUG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC31 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109082532 ^@ http://purl.uniprot.org/uniprot/A0A8C2I395 ^@ Similarity ^@ Belongs to the galactose-3-O-sulfotransferase family. http://togogenome.org/gene/7962:LOC109070127 ^@ http://purl.uniprot.org/uniprot/A0A8C1XLU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109093613 ^@ http://purl.uniprot.org/uniprot/A0A8C1HFL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STARD3 family.|||Endosome membrane|||Late endosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109094354 ^@ http://purl.uniprot.org/uniprot/A0A8C2GHX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109110275 ^@ http://purl.uniprot.org/uniprot/A0A8C1PN73 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/7962:LOC109047424 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109100764 ^@ http://purl.uniprot.org/uniprot/A0A8C1FYD2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109109303 ^@ http://purl.uniprot.org/uniprot/A0A8C1G6C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109048720 ^@ http://purl.uniprot.org/uniprot/A0A8C1AST9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109065582 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8W0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109096800 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109109144 ^@ http://purl.uniprot.org/uniprot/A0A8C1JSI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:LOC109087881 ^@ http://purl.uniprot.org/uniprot/A0A8C1CT73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7962:cdr2b ^@ http://purl.uniprot.org/uniprot/A0A8C1DMZ8 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/7962:LOC109064872 ^@ http://purl.uniprot.org/uniprot/A0A8C1QSR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STAM family.|||Early endosome membrane http://togogenome.org/gene/7962:LOC109094153 ^@ http://purl.uniprot.org/uniprot/A0A8C1CSJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAUS3 family.|||spindle http://togogenome.org/gene/7962:LOC109096996 ^@ http://purl.uniprot.org/uniprot/A0A8C1BGN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Membrane|||Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. http://togogenome.org/gene/7962:LOC109079406 ^@ http://purl.uniprot.org/uniprot/A0A8C1CX30 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109051860 ^@ http://purl.uniprot.org/uniprot/A0A0M5MSF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/7962:LOC109079784 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q1I2 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:LOC109048890 ^@ http://purl.uniprot.org/uniprot/A0A8C1H4E6 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/7962:msx3 ^@ http://purl.uniprot.org/uniprot/A0A8C1NK36 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062092 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZJ9 ^@ Similarity ^@ Belongs to the MHC class I family. http://togogenome.org/gene/7962:gng14 ^@ http://purl.uniprot.org/uniprot/A0A8C1BUS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109106929 ^@ http://purl.uniprot.org/uniprot/A0A8C1MW15 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/7962:LOC109076143 ^@ http://purl.uniprot.org/uniprot/A0A8C1PZ21 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/7962:LOC109055975 ^@ http://purl.uniprot.org/uniprot/A0A8C1JIB4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109095460 ^@ http://purl.uniprot.org/uniprot/A0A8C1XQE3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OCIAD1 family.|||Endosome|||Interacts with STAT3.|||Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.|||The OCIA domain is necessary and sufficient for endosomal localization. http://togogenome.org/gene/7962:LOC109060153 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0X1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109086995 ^@ http://purl.uniprot.org/uniprot/A0A8C1ELS0 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:LOC109081915 ^@ http://purl.uniprot.org/uniprot/A0A8C1D2Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/7962:zgc:101100 ^@ http://purl.uniprot.org/uniprot/A0A8C2FZ20 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109049860 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWT4 ^@ Function|||Subcellular Location Annotation ^@ Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.|||Cytoplasm http://togogenome.org/gene/7962:LOC109112540 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUV4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109074015 ^@ http://purl.uniprot.org/uniprot/A0A8C1HGX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109111951 ^@ http://purl.uniprot.org/uniprot/A0A8C2JHF0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/7962:LOC109047995 ^@ http://purl.uniprot.org/uniprot/A0A8C1AAY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HRG family.|||Endosome membrane|||Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109046706 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUY9 ^@ Similarity ^@ Belongs to the PDE6D/unc-119 family. http://togogenome.org/gene/7962:LOC109058152 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109095291 ^@ http://purl.uniprot.org/uniprot/A0A8C1MRT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109110220 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWM3 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109092968 ^@ http://purl.uniprot.org/uniprot/A0A8C2BC48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:si:dkey-190g11.3 ^@ http://purl.uniprot.org/uniprot/A0A8C0YC05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ANT/ATPSC lysine N-methyltransferase family.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109050440 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJH1 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:LOC109045903 ^@ http://purl.uniprot.org/uniprot/A0A8C1XVJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/7962:LOC109104492 ^@ http://purl.uniprot.org/uniprot/A0A8C1VGW7 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109093688 ^@ http://purl.uniprot.org/uniprot/A0A8C1CX75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM151 family.|||Membrane http://togogenome.org/gene/7962:cd164l2 ^@ http://purl.uniprot.org/uniprot/A0A8C1SCF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD164 family.|||Membrane http://togogenome.org/gene/7962:LOC109073937 ^@ http://purl.uniprot.org/uniprot/A0A8C1FPI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Nucleus speckle|||nucleolus http://togogenome.org/gene/7962:LOC109105907 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQS6 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:srd5a2a ^@ http://purl.uniprot.org/uniprot/A0A8C1TMU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane|||Microsome membrane http://togogenome.org/gene/7962:LOC109069805 ^@ http://purl.uniprot.org/uniprot/A0A8C1M466 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/7962:LOC122134014 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8E2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic13 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109084707 ^@ http://purl.uniprot.org/uniprot/A0A8C1I2Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYBC1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109046405 ^@ http://purl.uniprot.org/uniprot/A0A0C6E5A3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109102176 ^@ http://purl.uniprot.org/uniprot/A0A8C1TVD7 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/7962:LOC109102887 ^@ http://purl.uniprot.org/uniprot/A0A8C1AX45 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:LOC109069563 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVW8 ^@ Similarity ^@ Belongs to the SKI family. http://togogenome.org/gene/7962:zdhhc12b ^@ http://purl.uniprot.org/uniprot/A0A8C1DNZ5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:cs ^@ http://purl.uniprot.org/uniprot/A0A8C2EGC7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the citrate synthase family.|||Homodimer.|||Mitochondrion matrix http://togogenome.org/gene/7962:gpr34b ^@ http://purl.uniprot.org/uniprot/A0A8C1LJG8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109105845 ^@ http://purl.uniprot.org/uniprot/A0A169T7Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/7962:LOC109061612 ^@ http://purl.uniprot.org/uniprot/A0A8C1FI61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/7962:LOC109068452 ^@ http://purl.uniprot.org/uniprot/A0A8C1DL30 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7962:LOC109084573 ^@ http://purl.uniprot.org/uniprot/A0A8C1DXL3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109101697 ^@ http://purl.uniprot.org/uniprot/A0A8C1IIM4 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/7962:LOC109094533 ^@ http://purl.uniprot.org/uniprot/A0A8C0YBG7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. http://togogenome.org/gene/7962:LOC109055677 ^@ http://purl.uniprot.org/uniprot/A0A8C1EF89 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109088565 ^@ http://purl.uniprot.org/uniprot/A0A8C1B1C0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109064233 ^@ http://purl.uniprot.org/uniprot/A0A8C1J058|||http://purl.uniprot.org/uniprot/A0A8C1Q9X2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with UHRF2/NIRF.|||May be involved in cell cycle regulation.|||Nucleus http://togogenome.org/gene/7962:LOC109093595 ^@ http://purl.uniprot.org/uniprot/A0A8C1BU83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-15/IL-21 family.|||Secreted http://togogenome.org/gene/7962:LOC109050787 ^@ http://purl.uniprot.org/uniprot/A0A8C1BEH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL46 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109064808 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/7962:LOC109100196 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3X8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the noggin family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:serpinf1 ^@ http://purl.uniprot.org/uniprot/A0A8C1UYZ7 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109064699 ^@ http://purl.uniprot.org/uniprot/A0A8C1XUJ6 ^@ Similarity ^@ Belongs to the EVA1 family. http://togogenome.org/gene/7962:LOC109100422 ^@ http://purl.uniprot.org/uniprot/A0A8C2ADT4 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/7962:LOC109059299 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZPC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||May be involved in sexual development.|||Nucleus http://togogenome.org/gene/7962:pdx1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109056673 ^@ http://purl.uniprot.org/uniprot/A0A8C1V4U9 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/7962:eif3d ^@ http://purl.uniprot.org/uniprot/A0A8C1FMJ5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/7962:LOC109061989 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109063490 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:fam20cl ^@ http://purl.uniprot.org/uniprot/A0A8C1H1Q7 ^@ Similarity ^@ Belongs to the FAM20 family. http://togogenome.org/gene/7962:hnmt ^@ http://purl.uniprot.org/uniprot/A0A8C1CNB2 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/7962:steap3 ^@ http://purl.uniprot.org/uniprot/A0A8C1N2M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STEAP family.|||Endosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109095228 ^@ http://purl.uniprot.org/uniprot/A0A8C1IJA1|||http://purl.uniprot.org/uniprot/A0A8C1ZWN2 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pentraxin family.|||Binds 2 calcium ions per subunit.|||Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109060954 ^@ http://purl.uniprot.org/uniprot/A0A8C1CVU5 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109104957 ^@ http://purl.uniprot.org/uniprot/A0A8C0YUF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:dyrk2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EI81|||http://purl.uniprot.org/uniprot/A0A8C1EKB1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/7962:LOC109109884 ^@ http://purl.uniprot.org/uniprot/A0A8C1LSQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HNF1 homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109109253 ^@ http://purl.uniprot.org/uniprot/A0A8C1B9Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the distal-less homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109069992 ^@ http://purl.uniprot.org/uniprot/A0A8C1PUH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7962:LOC109066600 ^@ http://purl.uniprot.org/uniprot/A0A169T883 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/7962:LOC109074040 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMG2 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:si:dkey-1k23.3 ^@ http://purl.uniprot.org/uniprot/A0A8C1AIK0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:dynll2b ^@ http://purl.uniprot.org/uniprot/A0A8C1Q3X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109062766 ^@ http://purl.uniprot.org/uniprot/A0A8C1SPQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109099440 ^@ http://purl.uniprot.org/uniprot/A0A8C1HD37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Membrane http://togogenome.org/gene/7962:LOC109074803 ^@ http://purl.uniprot.org/uniprot/A0A8C1JJ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT2/3/5 family.|||Nucleus http://togogenome.org/gene/7962:abi2a ^@ http://purl.uniprot.org/uniprot/A0A8C0YAY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABI family.|||cytoskeleton|||filopodium|||lamellipodium http://togogenome.org/gene/7962:LOC109076836 ^@ http://purl.uniprot.org/uniprot/A0A8C2HUP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ripply family.|||Nucleus http://togogenome.org/gene/7962:LOC109105017 ^@ http://purl.uniprot.org/uniprot/A0A8C0XWH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||May be required for pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/7962:zgc:171566 ^@ http://purl.uniprot.org/uniprot/A0A8C2J9Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||extracellular space http://togogenome.org/gene/7962:cebpb ^@ http://purl.uniprot.org/uniprot/A0A8C1W9N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. C/EBP subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109096562 ^@ http://purl.uniprot.org/uniprot/A0A8C1J2Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/7962:LOC109107007 ^@ http://purl.uniprot.org/uniprot/A0A8C1NE02 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/7962:tmx2b ^@ http://purl.uniprot.org/uniprot/A0A8C1A0Z1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109086799 ^@ http://purl.uniprot.org/uniprot/A0A8C1F152 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARMET family.|||Secreted http://togogenome.org/gene/7962:LOC109062663 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109106071 ^@ http://purl.uniprot.org/uniprot/A0A8C2CZN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC42SE/SPEC family.|||Cell membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/7962:foxj1b ^@ http://purl.uniprot.org/uniprot/A0A8C1QBD0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109107206 ^@ http://purl.uniprot.org/uniprot/A0A8C2K1X9 ^@ Similarity ^@ Belongs to the acetyltransferase family. MAK3 subfamily. http://togogenome.org/gene/7962:mfsd8l1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HIV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109098533 ^@ http://purl.uniprot.org/uniprot/A0A8C1HWI6 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/7962:LOC109087360 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERM4 ^@ Similarity ^@ Belongs to the UPF0449 family. http://togogenome.org/gene/7962:LOC109057899 ^@ http://purl.uniprot.org/uniprot/A0A8C1DHV8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109090937 ^@ http://purl.uniprot.org/uniprot/A0A8C1AYJ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109070192 ^@ http://purl.uniprot.org/uniprot/A0A8C2DD20 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109097276 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y7C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:LOC109061145 ^@ http://purl.uniprot.org/uniprot/A0A8C1CV39 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:si:ch211-15p9.2 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y926 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109103035 ^@ http://purl.uniprot.org/uniprot/A0A8C1PX82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.|||extracellular matrix http://togogenome.org/gene/7962:LOC109057694 ^@ http://purl.uniprot.org/uniprot/A0A8C2KIY9 ^@ Similarity ^@ Belongs to the FAM167 (SEC) family. http://togogenome.org/gene/7962:LOC109083513 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/7962:hbegfa ^@ http://purl.uniprot.org/uniprot/A0A8C1CA20 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109057721 ^@ http://purl.uniprot.org/uniprot/A0A8C1TSK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109045732 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5R4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109049799 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3E3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:cldn30 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:ackr3b ^@ http://purl.uniprot.org/uniprot/A0A8C1GR70 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109093143 ^@ http://purl.uniprot.org/uniprot/A0A8C1FA51 ^@ Similarity ^@ Belongs to the peptidase C65 family. http://togogenome.org/gene/7962:LOC109064552 ^@ http://purl.uniprot.org/uniprot/A0A8C1EC81 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109050036 ^@ http://purl.uniprot.org/uniprot/A0A8C1G0W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/7962:bnip4 ^@ http://purl.uniprot.org/uniprot/A0A8C1J254 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/7962:dguok ^@ http://purl.uniprot.org/uniprot/A0A8C1E9I8 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/7962:LOC109091542 ^@ http://purl.uniprot.org/uniprot/A0A8C1DNS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/7962:pde4cb ^@ http://purl.uniprot.org/uniprot/A0A8C0YB58 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109066733 ^@ http://purl.uniprot.org/uniprot/A0A8C1XD02 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:hoxa5a ^@ http://purl.uniprot.org/uniprot/A0A8C1K0M8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109113613 ^@ http://purl.uniprot.org/uniprot/A0A8C1DYZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:ext2 ^@ http://purl.uniprot.org/uniprot/A0A8C2HKD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109110948 ^@ http://purl.uniprot.org/uniprot/A0A8C1I2F3 ^@ Similarity ^@ Belongs to the FAM110 family. http://togogenome.org/gene/7962:LOC109052672 ^@ http://purl.uniprot.org/uniprot/A0A8C1E4S8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.|||Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109110367 ^@ http://purl.uniprot.org/uniprot/A0A8C2C745 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||Nucleus http://togogenome.org/gene/7962:LOC109072814 ^@ http://purl.uniprot.org/uniprot/A0A8C1C7I8 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/7962:tma16 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQ44 ^@ Function|||Similarity|||Subunit ^@ Associates with pre-60S ribosomal particles.|||Belongs to the TMA16 family.|||Involved in the biogenesis of the 60S ribosomal subunit in the nucleus. http://togogenome.org/gene/7962:LOC109062313 ^@ http://purl.uniprot.org/uniprot/A0A8C2CRW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucose-6-phosphatase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:six1a ^@ http://purl.uniprot.org/uniprot/A0A8C1EU48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SIX/Sine oculis homeobox family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109071095 ^@ http://purl.uniprot.org/uniprot/A0A8C1CKD4|||http://purl.uniprot.org/uniprot/A0A8C2I0X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Engrailed homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109112006 ^@ http://purl.uniprot.org/uniprot/A0A8C1SP89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||cis-Golgi network http://togogenome.org/gene/7962:LOC109107216 ^@ http://purl.uniprot.org/uniprot/A0A8C1A8V6 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:LOC109097837 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLZ5 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZP domain family. ZPC subfamily.|||Cell membrane|||Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.|||Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.|||The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.|||Zona pellucida http://togogenome.org/gene/7962:LOC109060906 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZ68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:zgc:109913 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNZ8 ^@ Similarity ^@ Belongs to the RGS7BP/RGS9BP family. http://togogenome.org/gene/7962:sla1a ^@ http://purl.uniprot.org/uniprot/A0A8C1AL91 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:hamp ^@ http://purl.uniprot.org/uniprot/A0A8C1JSQ4|||http://purl.uniprot.org/uniprot/A0A8C1TG91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hepcidin family.|||Secreted http://togogenome.org/gene/7962:il6 ^@ http://purl.uniprot.org/uniprot/A0A8C1DL06 ^@ Similarity ^@ Belongs to the IL-6 superfamily. http://togogenome.org/gene/7962:LOC109095426 ^@ http://purl.uniprot.org/uniprot/A0A8C1BL41 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109084547 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JUPITER family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109074670 ^@ http://purl.uniprot.org/uniprot/A0A8C1PIW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109094636 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/7962:LOC109070731 ^@ http://purl.uniprot.org/uniprot/A0A8C1ESY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109062112 ^@ http://purl.uniprot.org/uniprot/A0A8C1PQD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/7962:LOC109052860 ^@ http://purl.uniprot.org/uniprot/A0A8C1RB89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAVIN family.|||caveola http://togogenome.org/gene/7962:LOC109061318 ^@ http://purl.uniprot.org/uniprot/A0A5Q2UAQ2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109086062 ^@ http://purl.uniprot.org/uniprot/A0A8C1NC10 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109096989 ^@ http://purl.uniprot.org/uniprot/A0A8C1BFA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/7962:LOC109098442 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6N8 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/7962:atp5mf ^@ http://purl.uniprot.org/uniprot/A0A8C1D4D9 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/7962:get1 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q6S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WRB/GET1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:atp5l ^@ http://purl.uniprot.org/uniprot/A0A8C2KNU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion http://togogenome.org/gene/7962:KEF38_p02 ^@ http://purl.uniprot.org/uniprot/P24982 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Mitochondrion membrane http://togogenome.org/gene/7962:tacr1b ^@ http://purl.uniprot.org/uniprot/A0A8C0Y856 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109054871 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKE3 ^@ Similarity ^@ Belongs to the BicD family. http://togogenome.org/gene/7962:LOC109103249 ^@ http://purl.uniprot.org/uniprot/A0A8C2KHJ2 ^@ Similarity ^@ Belongs to the CRK family. http://togogenome.org/gene/7962:LOC109078309 ^@ http://purl.uniprot.org/uniprot/A0A8C1IDS6 ^@ Similarity ^@ Belongs to the RIB43A family. http://togogenome.org/gene/7962:spring1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YD25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPRING family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109081974 ^@ http://purl.uniprot.org/uniprot/A0A8C1HUS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM97/sigma-2 receptor family.|||Endoplasmic reticulum membrane|||Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.|||Membrane|||Nucleus membrane|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109062420 ^@ http://purl.uniprot.org/uniprot/A0A8C1B6M4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C14A family.|||Cytoplasm|||Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.|||Nucleus http://togogenome.org/gene/7962:LOC109085375 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. http://togogenome.org/gene/7962:LOC109083982 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109074657 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKG0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:kif20a ^@ http://purl.uniprot.org/uniprot/A0A8C1HT82 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/7962:tpt1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYI9 ^@ Similarity ^@ Belongs to the TCTP family. http://togogenome.org/gene/7962:cdip1 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109110030 ^@ http://purl.uniprot.org/uniprot/A0A8C1CN47 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109087011 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKV8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109053777 ^@ http://purl.uniprot.org/uniprot/A0A8C1DW08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/7962:LOC109084520 ^@ http://purl.uniprot.org/uniprot/A0A8C2FQX7 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109067152 ^@ http://purl.uniprot.org/uniprot/A0A8C1EE80 ^@ Subcellular Location Annotation|||Subunit ^@ Membrane|||The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. http://togogenome.org/gene/7962:LOC109081945 ^@ http://purl.uniprot.org/uniprot/A0A8C1WT20 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/7962:LOC109059533 ^@ http://purl.uniprot.org/uniprot/A0A8C1E662 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109105092 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVT4 ^@ Similarity ^@ Belongs to the HINT family. http://togogenome.org/gene/7962:LOC109088764 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIB7 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/7962:LOC109057801 ^@ http://purl.uniprot.org/uniprot/A0A8C1UZN4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109064793 ^@ http://purl.uniprot.org/uniprot/A0A8C1D4R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFC2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:tsc22d3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HEJ1 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/7962:LOC109101740 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWW2 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/7962:stc1 ^@ http://purl.uniprot.org/uniprot/A0A8C1LWD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked.|||Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales. http://togogenome.org/gene/7962:LOC109088826 ^@ http://purl.uniprot.org/uniprot/A0A8C1F0T3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109051910 ^@ http://purl.uniprot.org/uniprot/A0A8C1C3V1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/7962:LOC109106237 ^@ http://purl.uniprot.org/uniprot/A0A8C2D5M5 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109093046 ^@ http://purl.uniprot.org/uniprot/A0A8C2CCZ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/7962:LOC109051989 ^@ http://purl.uniprot.org/uniprot/A0A0K2RVW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109107784 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7962:yipf6 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/7962:vsnl1b ^@ http://purl.uniprot.org/uniprot/A0A8C1HTD5 ^@ Function ^@ Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. http://togogenome.org/gene/7962:sostdc1a ^@ http://purl.uniprot.org/uniprot/A0A8C0YEX5 ^@ Caution|||Similarity ^@ Belongs to the sclerostin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:taf12 ^@ http://purl.uniprot.org/uniprot/A0A8C1J4P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF12 family.|||Nucleus http://togogenome.org/gene/7962:grpel2 ^@ http://purl.uniprot.org/uniprot/A0A8C1KH99 ^@ Similarity ^@ Belongs to the GrpE family. http://togogenome.org/gene/7962:LOC109068345 ^@ http://purl.uniprot.org/uniprot/A0A8C1C3Y4 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/7962:LOC109111485 ^@ http://purl.uniprot.org/uniprot/A0A8C1KQG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL53 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109086063 ^@ http://purl.uniprot.org/uniprot/A0A8C1HVQ3 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:crygn1 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y6Y6 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:cldn10d ^@ http://purl.uniprot.org/uniprot/A0A8C1FFW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109109707 ^@ http://purl.uniprot.org/uniprot/A0A8C0YR74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Membrane http://togogenome.org/gene/7962:LOC109080154 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSY2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:fgf1a ^@ http://purl.uniprot.org/uniprot/A0A059T9K9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||Nucleus|||Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.|||Secreted|||cell cortex|||cytosol http://togogenome.org/gene/7962:LOC109064254 ^@ http://purl.uniprot.org/uniprot/A0A8C1QEH0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAPRTase family.|||Cytoplasm|||Homodimer.|||Nucleus|||Secreted http://togogenome.org/gene/7962:pdcd10a ^@ http://purl.uniprot.org/uniprot/A0A8C1ICD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cell membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109046507 ^@ http://purl.uniprot.org/uniprot/A0A8C1BV12 ^@ Similarity ^@ Belongs to the RAMP family. http://togogenome.org/gene/7962:LOC109053762 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZ76 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with PEX19.|||Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.|||Peroxisome membrane http://togogenome.org/gene/7962:sms ^@ http://purl.uniprot.org/uniprot/A0A8C1BCG8 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/7962:LOC109070125 ^@ http://purl.uniprot.org/uniprot/A0A8C1EI68 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/7962:LOC109049241 ^@ http://purl.uniprot.org/uniprot/A0A8C1J5M3 ^@ Similarity ^@ Belongs to the PPDPF family. http://togogenome.org/gene/7962:LOC109055997 ^@ http://purl.uniprot.org/uniprot/A0A8C1EID1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/7962:nrn1b ^@ http://purl.uniprot.org/uniprot/A0A8C1D6A7 ^@ Similarity ^@ Belongs to the neuritin family. http://togogenome.org/gene/7962:LOC109078615 ^@ http://purl.uniprot.org/uniprot/A0A8C1CT20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the neugrin family.|||Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.|||Mitochondrion membrane|||Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. http://togogenome.org/gene/7962:LOC109071911 ^@ http://purl.uniprot.org/uniprot/A0A8C1HLV6 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:natd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HI42 ^@ Similarity ^@ Belongs to the NATD1 family. http://togogenome.org/gene/7962:naif1 ^@ http://purl.uniprot.org/uniprot/A0A8C1H781 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:hspb7 ^@ http://purl.uniprot.org/uniprot/A0A8C2KRH5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109047427 ^@ http://purl.uniprot.org/uniprot/A0A8C1S679 ^@ Function|||Similarity ^@ Belongs to the profilin family.|||Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. http://togogenome.org/gene/7962:LOC109060996 ^@ http://purl.uniprot.org/uniprot/A0A8C1IIL9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109095483 ^@ http://purl.uniprot.org/uniprot/A0A8C1IR30 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:LOC109102103 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y393 ^@ Function ^@ May be involved in neurite outgrowth. http://togogenome.org/gene/7962:LOC109090403 ^@ http://purl.uniprot.org/uniprot/A0A8C1R5N2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein sulfotransferase family.|||Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.|||Golgi apparatus membrane http://togogenome.org/gene/7962:LOC109092917 ^@ http://purl.uniprot.org/uniprot/A0A8C1CFE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C12 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109070811 ^@ http://purl.uniprot.org/uniprot/A0A8C1GDL6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109094704 ^@ http://purl.uniprot.org/uniprot/A0A8C1EAC0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||E3 ubiquitin ligase. http://togogenome.org/gene/7962:cxxc5b ^@ http://purl.uniprot.org/uniprot/A0A8C1GMA5|||http://purl.uniprot.org/uniprot/A0A8C1GWY5|||http://purl.uniprot.org/uniprot/A0A8C1SKU6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109070925 ^@ http://purl.uniprot.org/uniprot/A0A8C2BUE3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/7962:b4galt1l ^@ http://purl.uniprot.org/uniprot/A0A8C1AF75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/7962:LOC109046679 ^@ http://purl.uniprot.org/uniprot/A0A8C1TIJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109080209 ^@ http://purl.uniprot.org/uniprot/A0A8C1G0G9 ^@ Function|||Similarity ^@ Belongs to the SWI5/SAE3 family.|||Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination. http://togogenome.org/gene/7962:LOC109098509 ^@ http://purl.uniprot.org/uniprot/A0A089ZW71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109052528 ^@ http://purl.uniprot.org/uniprot/A0A8C0YJ02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family. Highly divergent.|||Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.|||Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.|||Secreted http://togogenome.org/gene/7962:LOC109060982 ^@ http://purl.uniprot.org/uniprot/A0A8C1HSQ6 ^@ Similarity ^@ Belongs to the dermatopontin family. http://togogenome.org/gene/7962:extl3 ^@ http://purl.uniprot.org/uniprot/A0A8C1H331 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109046572 ^@ http://purl.uniprot.org/uniprot/A0A8C1RRB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/7962:LOC109103060 ^@ http://purl.uniprot.org/uniprot/A0A8C1W8A7 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. http://togogenome.org/gene/7962:igf2b ^@ http://purl.uniprot.org/uniprot/A0A8C1V7J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109072498 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJ11 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:arpc5la ^@ http://purl.uniprot.org/uniprot/A0A8C0YKR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.|||cytoskeleton http://togogenome.org/gene/7962:LOC109083114 ^@ http://purl.uniprot.org/uniprot/A0A8C2ILB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:zgc:153981 ^@ http://purl.uniprot.org/uniprot/A0A8C1MRQ5 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/7962:si:dkey-58f10.6 ^@ http://purl.uniprot.org/uniprot/A0A8C1BVH8 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:nfya ^@ http://purl.uniprot.org/uniprot/A0A8C1HRY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/7962:mrpl42 ^@ http://purl.uniprot.org/uniprot/A0A8C0YA89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL42 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109098068 ^@ http://purl.uniprot.org/uniprot/A0A8C1BMC3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/7962:LOC109109158 ^@ http://purl.uniprot.org/uniprot/A0A8C1AK85 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/7962:LOC109062999 ^@ http://purl.uniprot.org/uniprot/A0A8C2K6R4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:foxp3a ^@ http://purl.uniprot.org/uniprot/A0A8C1BEM1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:tmprss13b ^@ http://purl.uniprot.org/uniprot/A0A8C1C9A8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109097999 ^@ http://purl.uniprot.org/uniprot/A0A8C1DV09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109099402 ^@ http://purl.uniprot.org/uniprot/A0A8C1MJW8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:LOC109106117 ^@ http://purl.uniprot.org/uniprot/A0A8C1ASF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/7962:si:dkey-120c6.5 ^@ http://purl.uniprot.org/uniprot/A0A8C1IV34 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109050616 ^@ http://purl.uniprot.org/uniprot/A0A8C2KCI2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109069170 ^@ http://purl.uniprot.org/uniprot/A0A8C2BME5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mab-21 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109074129 ^@ http://purl.uniprot.org/uniprot/A0A8C1KVG3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:ampd3b ^@ http://purl.uniprot.org/uniprot/A0A8C1CUX8|||http://purl.uniprot.org/uniprot/A0A8C1GZ32 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/7962:LOC109098449 ^@ http://purl.uniprot.org/uniprot/A0A8C0YRB7 ^@ Similarity ^@ Belongs to the TACO1 family. http://togogenome.org/gene/7962:LOC109073323 ^@ http://purl.uniprot.org/uniprot/A0A8C1K0J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM88 family.|||Membrane http://togogenome.org/gene/7962:LOC109095915 ^@ http://purl.uniprot.org/uniprot/A0A8C2PPS8 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/7962:LOC109076110 ^@ http://purl.uniprot.org/uniprot/A0A8C1CP34 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/7962:LOC109080249 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMT6 ^@ Similarity ^@ Belongs to the costars family. http://togogenome.org/gene/7962:LOC109071955 ^@ http://purl.uniprot.org/uniprot/A0A8C1D433 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:fam174b ^@ http://purl.uniprot.org/uniprot/A0A8C1G293 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/7962:LOC109075438 ^@ http://purl.uniprot.org/uniprot/A0A8C2IMY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:zgc:162193 ^@ http://purl.uniprot.org/uniprot/A0A8C0YEN2 ^@ Similarity ^@ Belongs to the TCAF family. http://togogenome.org/gene/7962:LOC109060078 ^@ http://purl.uniprot.org/uniprot/A0A8C1IX43 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/7962:LOC109097921 ^@ http://purl.uniprot.org/uniprot/A0A8C1J5V5 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:cdk5rap3 ^@ http://purl.uniprot.org/uniprot/A0A8C1I5J1 ^@ Similarity ^@ Belongs to the CDK5RAP3 family. http://togogenome.org/gene/7962:tmsb1 ^@ http://purl.uniprot.org/uniprot/Q9I955 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).|||cytoskeleton http://togogenome.org/gene/7962:chst11 ^@ http://purl.uniprot.org/uniprot/A0A8C1ECK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109097029 ^@ http://purl.uniprot.org/uniprot/A0A8C1BKY8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:tlr22 ^@ http://purl.uniprot.org/uniprot/A0A169T826 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/7962:LOC109055150 ^@ http://purl.uniprot.org/uniprot/A0A8C1AD38 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109072067 ^@ http://purl.uniprot.org/uniprot/A0A8C2BY69 ^@ Similarity ^@ Belongs to the NGF-beta family. http://togogenome.org/gene/7962:LOC109079465 ^@ http://purl.uniprot.org/uniprot/A0A8C1V7M7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109067084 ^@ http://purl.uniprot.org/uniprot/A0A8C1CXN9 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109093430 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:ca8h12orf43 ^@ http://purl.uniprot.org/uniprot/A0A8C0YN71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUSTOS family.|||Nucleus envelope http://togogenome.org/gene/7962:insl3 ^@ http://purl.uniprot.org/uniprot/A0A8C1RQU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted|||Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor. http://togogenome.org/gene/7962:LOC109055586 ^@ http://purl.uniprot.org/uniprot/A0A8C2GS96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/7962:krtcap2 ^@ http://purl.uniprot.org/uniprot/A0A8C1NX24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KRTCAP2 family.|||Membrane http://togogenome.org/gene/7962:LOC109083109 ^@ http://purl.uniprot.org/uniprot/A0A8C1F923 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/7962:LOC109080455 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQY5 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:dbx2 ^@ http://purl.uniprot.org/uniprot/A0A8C1DYI4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109086803 ^@ http://purl.uniprot.org/uniprot/A0A8C1HYN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/7962:LOC109046658 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109054947 ^@ http://purl.uniprot.org/uniprot/A0A8C0YH67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UCMA family.|||May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.|||extracellular matrix http://togogenome.org/gene/7962:LOC109089344 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109110189 ^@ http://purl.uniprot.org/uniprot/A0A8C1AG59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109079819 ^@ http://purl.uniprot.org/uniprot/A0A8C2K0M0 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109098415 ^@ http://purl.uniprot.org/uniprot/A0A8C1N240 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Cell membrane|||Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.|||Membrane http://togogenome.org/gene/7962:LOC109065787 ^@ http://purl.uniprot.org/uniprot/A0A8C1CS99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Cell membrane|||Membrane|||extracellular exosome http://togogenome.org/gene/7962:mc1r ^@ http://purl.uniprot.org/uniprot/L7UNP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. http://togogenome.org/gene/7962:LOC109070305 ^@ http://purl.uniprot.org/uniprot/A0A8C1CBV4|||http://purl.uniprot.org/uniprot/A0A8C2FV05 ^@ Similarity ^@ Belongs to the RENT3 family. http://togogenome.org/gene/7962:sdhdb ^@ http://purl.uniprot.org/uniprot/A0A8C1RC41 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CybS family.|||Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109079069 ^@ http://purl.uniprot.org/uniprot/A0A8C1EW73 ^@ Function ^@ Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. http://togogenome.org/gene/7962:emc9 ^@ http://purl.uniprot.org/uniprot/A0A8C1LC14 ^@ Similarity ^@ Belongs to the EMC8/EMC9 family. http://togogenome.org/gene/7962:ppp4r2b ^@ http://purl.uniprot.org/uniprot/A0A8C1FYR0 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/7962:LOC109083015 ^@ http://purl.uniprot.org/uniprot/A0A8C1DNQ0 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109080327 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/7962:prkcq ^@ http://purl.uniprot.org/uniprot/A0A8C1IXC5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/7962:LOC109104857 ^@ http://purl.uniprot.org/uniprot/A0A8C2AHG6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:pvalb1 ^@ http://purl.uniprot.org/uniprot/A0A8C1USQ1 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:kcnk3a ^@ http://purl.uniprot.org/uniprot/A0A8C2J013 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109107143 ^@ http://purl.uniprot.org/uniprot/A0A8C1MCF1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109073733 ^@ http://purl.uniprot.org/uniprot/A0A8C2ADL6|||http://purl.uniprot.org/uniprot/A0A8C2ADN1 ^@ Function|||Similarity ^@ Belongs to the profilin family.|||Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. http://togogenome.org/gene/7962:LOC109058704 ^@ http://purl.uniprot.org/uniprot/A0A8C1E4U9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:slc5a6a ^@ http://purl.uniprot.org/uniprot/A0A8C0YGW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/7962:LOC109108986 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3M8 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/7962:LOC109094105 ^@ http://purl.uniprot.org/uniprot/A0A8C2D0C0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexophilin family.|||May be signaling molecules that resemble neuropeptides.|||Secreted http://togogenome.org/gene/7962:LOC109080133 ^@ http://purl.uniprot.org/uniprot/A0A089ZZA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109088927 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109069991 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWG8 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/7962:hbba2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDQ2 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109065740 ^@ http://purl.uniprot.org/uniprot/A0A8C2KSS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:rxfp3.2b ^@ http://purl.uniprot.org/uniprot/A0A8C2FFL7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109101501 ^@ http://purl.uniprot.org/uniprot/A0A8C1FAV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/7962:LOC109110225 ^@ http://purl.uniprot.org/uniprot/A0A8C1KYN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM U1 A/B'' family.|||Nucleus http://togogenome.org/gene/7962:sox19a ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2L1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109053993 ^@ http://purl.uniprot.org/uniprot/A0A8C1CWH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the round spermatid basic protein 1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109083416 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y8W6|||http://purl.uniprot.org/uniprot/A0A8C1A1X4 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/7962:trappc4 ^@ http://purl.uniprot.org/uniprot/A0A8C2CCC8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/7962:LOC109113218 ^@ http://purl.uniprot.org/uniprot/A0A8C1BV84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109081647 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.|||Secreted http://togogenome.org/gene/7962:armc1l ^@ http://purl.uniprot.org/uniprot/A0A8C1HAH4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109045060 ^@ http://purl.uniprot.org/uniprot/A0A8C1NQZ4 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/7962:LOC109110082 ^@ http://purl.uniprot.org/uniprot/A0A8C2C9L3 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/7962:derl3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HKD4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109057496 ^@ http://purl.uniprot.org/uniprot/A0A8C1SU37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CELF/BRUNOL family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:hbae5 ^@ http://purl.uniprot.org/uniprot/A0A8C1F676 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109092958 ^@ http://purl.uniprot.org/uniprot/A0A8C1E8K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with HDAC7 and KAT5.|||Membrane|||Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. http://togogenome.org/gene/7962:LOC109094249 ^@ http://purl.uniprot.org/uniprot/A0A8C2DTC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/7962:LOC109063537 ^@ http://purl.uniprot.org/uniprot/A0A8C1N1K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109095819 ^@ http://purl.uniprot.org/uniprot/A0A8C1AY42 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/7962:LOC109057988 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKK3 ^@ Similarity ^@ Belongs to the REXO4 family. http://togogenome.org/gene/7962:cldn23l ^@ http://purl.uniprot.org/uniprot/A0A8C1D493 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:eif3g ^@ http://purl.uniprot.org/uniprot/A0A8C1UIH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit G family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. http://togogenome.org/gene/7962:ndufb4 ^@ http://purl.uniprot.org/uniprot/A0A8C1FIV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB4 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109078787 ^@ http://purl.uniprot.org/uniprot/A0A8C1PWT8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109065782 ^@ http://purl.uniprot.org/uniprot/A0A8C2HSX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:clic5a ^@ http://purl.uniprot.org/uniprot/A0A8C1GIB4 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/7962:LOC109101475 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQ73 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7962:LOC109091774 ^@ http://purl.uniprot.org/uniprot/A0A8C1LLV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ANKH family.|||Membrane|||Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter. http://togogenome.org/gene/7962:LOC109096538 ^@ http://purl.uniprot.org/uniprot/A0A8C1BCY0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109050674 ^@ http://purl.uniprot.org/uniprot/A0A8C1UH27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat ARPC1 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||Nucleus|||cytoskeleton http://togogenome.org/gene/7962:LOC109093554 ^@ http://purl.uniprot.org/uniprot/A0A8C2B2T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109085261 ^@ http://purl.uniprot.org/uniprot/A0A8C2ID01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.|||Secreted http://togogenome.org/gene/7962:LOC109058743 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2B8 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/7962:tmbim1a ^@ http://purl.uniprot.org/uniprot/A0A8C1Y7G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/7962:LOC109104321 ^@ http://purl.uniprot.org/uniprot/A0A8C1I263 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109102251 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6D6|||http://purl.uniprot.org/uniprot/A0A8C1QML8 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/7962:LOC109047088 ^@ http://purl.uniprot.org/uniprot/A5LG07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109113146 ^@ http://purl.uniprot.org/uniprot/A0A8C1K7D7 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. AMIGO family. http://togogenome.org/gene/7962:LOC109102997 ^@ http://purl.uniprot.org/uniprot/A0A8C1AEB4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109055651 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109053201 ^@ http://purl.uniprot.org/uniprot/A0A8C1V567 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:LOC109103292 ^@ http://purl.uniprot.org/uniprot/A0A8C1D8U0|||http://purl.uniprot.org/uniprot/A0A8C1DB00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EAF6 family.|||Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.|||Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.|||kinetochore|||nucleolus http://togogenome.org/gene/7962:LOC109077210 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPA8 ^@ Similarity ^@ Belongs to the SKI family. http://togogenome.org/gene/7962:LOC109095399 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3X6 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7962:LOC109065212 ^@ http://purl.uniprot.org/uniprot/A0A8C1BCE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/7962:ypel5 ^@ http://purl.uniprot.org/uniprot/A0A8C1NXF0 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109108209 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Vesicular transporter family.|||Membrane http://togogenome.org/gene/7962:rpp30 ^@ http://purl.uniprot.org/uniprot/A0A8C2GA14 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/7962:LOC109084720 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZ39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/7962:KEF38_p11 ^@ http://purl.uniprot.org/uniprot/P24985 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 2 heme A groups non-covalently per subunit.|||Binds a copper B center.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). As a newly synthesized protein, rapidly incorporates into a multi-subunit assembly intermediate in the inner membrane, called MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase) complex, whose core components are COA3/MITRAC12 and COX14. Within the MITRAC complex, interacts with COA3 and with SMIM20/MITRAC7; the interaction with SMIM20 stabilizes the newly synthesized MT-CO1 and prevents its premature turnover. Interacts with TMEM177 in a COX20-dependent manner (By similarity).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109094399 ^@ http://purl.uniprot.org/uniprot/A0A8C1AAT0|||http://purl.uniprot.org/uniprot/A0A8C1H045 ^@ Function|||Similarity ^@ Belongs to the calcitonin family.|||Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. http://togogenome.org/gene/7962:rflna ^@ http://purl.uniprot.org/uniprot/A0A8C1LQ02 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Refilin family.|||Interacts with FLNA and FLNB.|||cytoskeleton http://togogenome.org/gene/7962:saa ^@ http://purl.uniprot.org/uniprot/A0A1W6QDZ2 ^@ Function|||Similarity ^@ Belongs to the SAA family.|||Major acute phase reactant. Apolipoprotein of the HDL complex. http://togogenome.org/gene/7962:slc35a4 ^@ http://purl.uniprot.org/uniprot/A0A8C1B7Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Membrane http://togogenome.org/gene/7962:accs ^@ http://purl.uniprot.org/uniprot/A0A8C1H530 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/7962:LOC109104201 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPRE family.|||cytoskeleton http://togogenome.org/gene/7962:ccnd3 ^@ http://purl.uniprot.org/uniprot/A0A8C1FII5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109072893 ^@ http://purl.uniprot.org/uniprot/A0A8C1D456 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109090670 ^@ http://purl.uniprot.org/uniprot/A0A8C2D4I3 ^@ Function|||Subcellular Location Annotation ^@ Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/7962:mymk ^@ http://purl.uniprot.org/uniprot/A0A8C1FVY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:phpt1 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the janus family.|||Cytoplasm|||Exhibits phosphohistidine phosphatase activity.|||Monomer. http://togogenome.org/gene/7962:LOC109089054 ^@ http://purl.uniprot.org/uniprot/A0A8C1QCJ5 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/7962:sec11a ^@ http://purl.uniprot.org/uniprot/A0A8C2DWA4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Component of the signal peptidase complex.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109076842 ^@ http://purl.uniprot.org/uniprot/A0A8C1WIJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ripply family.|||Nucleus http://togogenome.org/gene/7962:dpf2l ^@ http://purl.uniprot.org/uniprot/A0A8C1U804 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/7962:bcl7bb ^@ http://purl.uniprot.org/uniprot/A0A8C1ECT5 ^@ Similarity ^@ Belongs to the BCL7 family. http://togogenome.org/gene/7962:LOC109093436 ^@ http://purl.uniprot.org/uniprot/A0A8C1J8N7 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/7962:LOC109082171 ^@ http://purl.uniprot.org/uniprot/A0A8C1RR70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Might be involved in growth regulation, and in myelinization in the peripheral nervous system. http://togogenome.org/gene/7962:adra2b ^@ http://purl.uniprot.org/uniprot/A0A8C1M4W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109078982 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQJ9|||http://purl.uniprot.org/uniprot/A0A8C1FQM1|||http://purl.uniprot.org/uniprot/A0A8C1T4V1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.|||Homodimer. Heterodimer; with a rar molecule.|||Nucleus|||Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. http://togogenome.org/gene/7962:LOC109090650 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJW0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. http://togogenome.org/gene/7962:LOC109105793 ^@ http://purl.uniprot.org/uniprot/A0A8C1C411 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD type 2 subfamily.|||Nucleus http://togogenome.org/gene/7962:zgc:172076 ^@ http://purl.uniprot.org/uniprot/A0A8C2F4L6 ^@ Caution|||Similarity ^@ Belongs to the ATP:guanido phosphotransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109098205 ^@ http://purl.uniprot.org/uniprot/A0A8C2JNP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the beta/gamma-crystallin family.|||Crystallins are the dominant structural components of the vertebrate eye lens.|||Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms. http://togogenome.org/gene/7962:LOC109084464 ^@ http://purl.uniprot.org/uniprot/A0A8C1LAZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/7962:LOC109106802 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQX6 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/7962:LOC109109285 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/7962:LOC109068203 ^@ http://purl.uniprot.org/uniprot/A0A8C1CUL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109052199 ^@ http://purl.uniprot.org/uniprot/A0A8C1H709 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109052505 ^@ http://purl.uniprot.org/uniprot/A0A8C1DHE0|||http://purl.uniprot.org/uniprot/A0A8C1HNU6 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/7962:mc2r ^@ http://purl.uniprot.org/uniprot/A0A8C1DPL9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).|||Membrane http://togogenome.org/gene/7962:LOC109070107 ^@ http://purl.uniprot.org/uniprot/A0A8C1HV71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109097745 ^@ http://purl.uniprot.org/uniprot/A0A8C1H437 ^@ Similarity ^@ Belongs to the UPF0687 family. http://togogenome.org/gene/7962:LOC109080932 ^@ http://purl.uniprot.org/uniprot/A0A8C1KG73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109083873 ^@ http://purl.uniprot.org/uniprot/A0A8C1VZT6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Basolateral cell membrane|||Belongs to the annexin family.|||Cell membrane|||Cytoplasm|||Lateral cell membrane|||Membrane|||Nucleus|||cilium http://togogenome.org/gene/7962:etv5a ^@ http://purl.uniprot.org/uniprot/A0A8C1HDL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:rabggtb ^@ http://purl.uniprot.org/uniprot/A0A8C1PD22 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/7962:foxl1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJ13 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109110206 ^@ http://purl.uniprot.org/uniprot/A0A8C1JKI2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062618 ^@ http://purl.uniprot.org/uniprot/A0A8C1HU04 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109100234 ^@ http://purl.uniprot.org/uniprot/A0A8C1RLL8 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Mitochondrion|||cytosol http://togogenome.org/gene/7962:LOC109111731 ^@ http://purl.uniprot.org/uniprot/A0A8C1PC18 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/7962:LOC109071020 ^@ http://purl.uniprot.org/uniprot/A0A8C1M677 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:rgs2 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZA10 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||cytosol http://togogenome.org/gene/7962:LOC109055484 ^@ http://purl.uniprot.org/uniprot/A0A8C2AS39 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/7962:LOC109099719 ^@ http://purl.uniprot.org/uniprot/A0A8C1NRK3 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:phospho2 ^@ http://purl.uniprot.org/uniprot/A0A8C1QJ70 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. PHOSPHO family. http://togogenome.org/gene/7962:LOC109094269 ^@ http://purl.uniprot.org/uniprot/A0A8C1A9Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:crygs4 ^@ http://purl.uniprot.org/uniprot/A0A8C2E861 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:elovl6 ^@ http://purl.uniprot.org/uniprot/A0A8C2CQQ1 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL6 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||N-Glycosylated. http://togogenome.org/gene/7962:LOC109095282 ^@ http://purl.uniprot.org/uniprot/A0A8C1B251|||http://purl.uniprot.org/uniprot/A0A8C1H5R9|||http://purl.uniprot.org/uniprot/A0A8C2F1T3|||http://purl.uniprot.org/uniprot/A0A8C2F2H3|||http://purl.uniprot.org/uniprot/A0A8C2F337|||http://purl.uniprot.org/uniprot/A0A8C2HKC8 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/7962:LOC109083196 ^@ http://purl.uniprot.org/uniprot/A0A8C1YWM3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109085604 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDY1 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:gnrhr4 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJA3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109053405 ^@ http://purl.uniprot.org/uniprot/A0A8C1B9N7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109094666 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/7962:ap3m2 ^@ http://purl.uniprot.org/uniprot/A0A8C1J0B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes medium subunit family.|||Cytoplasmic vesicle membrane|||Golgi apparatus http://togogenome.org/gene/7962:LOC109077492 ^@ http://purl.uniprot.org/uniprot/A0A8C1J386 ^@ Function ^@ Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH. http://togogenome.org/gene/7962:mtnr1ba ^@ http://purl.uniprot.org/uniprot/A0A8C1CNV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.|||Membrane http://togogenome.org/gene/7962:LOC109049854 ^@ http://purl.uniprot.org/uniprot/A0A8C1EM68 ^@ Similarity ^@ Belongs to the SKAP family. http://togogenome.org/gene/7962:ypel2b ^@ http://purl.uniprot.org/uniprot/A0A8C2JG89 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109050111 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HARBI1 family.|||Cytoplasm|||Nucleus|||Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. http://togogenome.org/gene/7962:LOC109064706 ^@ http://purl.uniprot.org/uniprot/A0A8C1CR56 ^@ Similarity ^@ Belongs to the EVA1 family. http://togogenome.org/gene/7962:LOC109065377 ^@ http://purl.uniprot.org/uniprot/A0A8C1HDH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.|||Forms a homohexamer that can probably bind six kinase subunits. http://togogenome.org/gene/7962:LOC109060821 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVD2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109045946 ^@ http://purl.uniprot.org/uniprot/A0A8C2EF51 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109087827 ^@ http://purl.uniprot.org/uniprot/A0A8C2F0I1 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/7962:tmem192 ^@ http://purl.uniprot.org/uniprot/A0A8C1ST76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM192 family.|||Late endosome|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109077116 ^@ http://purl.uniprot.org/uniprot/A0A8C1D1R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109056863 ^@ http://purl.uniprot.org/uniprot/A0A8C1C169|||http://purl.uniprot.org/uniprot/A0A8C1HCW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:htr5ab ^@ http://purl.uniprot.org/uniprot/A0A8C1Z4R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109050707 ^@ http://purl.uniprot.org/uniprot/A0A8C1FK77 ^@ Similarity ^@ Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily. http://togogenome.org/gene/7962:LOC109078237 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1F1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/7962:rnf175 ^@ http://purl.uniprot.org/uniprot/A0A8C1LHB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109100158 ^@ http://purl.uniprot.org/uniprot/A0A8C1NMX9 ^@ Similarity|||Subunit ^@ Belongs to the synuclein family.|||May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation. http://togogenome.org/gene/7962:LOC109061988 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109080208 ^@ http://purl.uniprot.org/uniprot/A0A8C1LL33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/7962:LOC109111751 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD164 family.|||Membrane http://togogenome.org/gene/7962:nap1l1 ^@ http://purl.uniprot.org/uniprot/A0A8C2AGP6 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/7962:LOC109086035 ^@ http://purl.uniprot.org/uniprot/A0A8C1PHV2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109074161 ^@ http://purl.uniprot.org/uniprot/A0A8C1M117 ^@ Cofactor|||Similarity ^@ Belongs to the paraoxonase family.|||Binds 2 calcium ions per subunit. http://togogenome.org/gene/7962:arl2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YN56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7962:med19b ^@ http://purl.uniprot.org/uniprot/A0A8C0XVB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 19 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:vps37c ^@ http://purl.uniprot.org/uniprot/A0A8C2IR56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Endosome membrane|||Late endosome membrane http://togogenome.org/gene/7962:pgpep1l ^@ http://purl.uniprot.org/uniprot/A0A8C0YQC6 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/7962:LOC109078546 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJB7 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109048116 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109098952 ^@ http://purl.uniprot.org/uniprot/A0A8C2F7L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109086882 ^@ http://purl.uniprot.org/uniprot/A0A8C1YV38 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/7962:LOC109064094 ^@ http://purl.uniprot.org/uniprot/A0A0A7XF68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted|||Somatostatin inhibits the release of somatotropin. http://togogenome.org/gene/7962:kcnk2a ^@ http://purl.uniprot.org/uniprot/A0A8C1EN23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109058815 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y074 ^@ Similarity ^@ Belongs to the polyprenol kinase family. http://togogenome.org/gene/7962:dyrk1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FQ08|||http://purl.uniprot.org/uniprot/A0A8C1FTP2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/7962:LOC109089205 ^@ http://purl.uniprot.org/uniprot/A0A8C1HMI6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pentraxin family.|||Binds 2 calcium ions per subunit.|||Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109050734 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||Part of the multisubunit TRAPP (transport protein particle) complex.|||cis-Golgi network http://togogenome.org/gene/7962:LOC109088526 ^@ http://purl.uniprot.org/uniprot/A0A8C2APC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAPTM4/LAPTM5 transporter family.|||Cell membrane|||Endomembrane system|||Endosome membrane|||Late endosome membrane|||Membrane|||multivesicular body lumen|||multivesicular body membrane http://togogenome.org/gene/7962:LOC109102142 ^@ http://purl.uniprot.org/uniprot/A0A8C1JZK5 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/7962:LOC109049973 ^@ http://purl.uniprot.org/uniprot/A0A8C1H7H3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase inhibitor family.|||Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.|||Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.|||Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.|||Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.|||Mitochondrion http://togogenome.org/gene/7962:LOC109062616 ^@ http://purl.uniprot.org/uniprot/A0A8C1TH96 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane magnesium transporter (TC 1.A.67) family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport. http://togogenome.org/gene/7962:LOC109083486 ^@ http://purl.uniprot.org/uniprot/A0A8C2LAV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109058424 ^@ http://purl.uniprot.org/uniprot/A0A8C2E802 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:fgf13b ^@ http://purl.uniprot.org/uniprot/A0A0C6EYP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||dendrite|||filopodium|||growth cone|||sarcolemma http://togogenome.org/gene/7962:LOC109112025 ^@ http://purl.uniprot.org/uniprot/A0A8C0YI26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109111334 ^@ http://purl.uniprot.org/uniprot/A0A8C1JI64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endothelin/sarafotoxin family.|||Secreted http://togogenome.org/gene/7962:LOC109070386 ^@ http://purl.uniprot.org/uniprot/A0A8C1QTC3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109077247 ^@ http://purl.uniprot.org/uniprot/A0A8C1TWF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bombesin/neuromedin-B/ranatensin family.|||Secreted http://togogenome.org/gene/7962:LOC109100277 ^@ http://purl.uniprot.org/uniprot/A0A8C1JHL8 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109064648 ^@ http://purl.uniprot.org/uniprot/A0A8C1FW11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SEC13 family.|||Lysosome membrane|||nuclear pore complex http://togogenome.org/gene/7962:LOC109080699 ^@ http://purl.uniprot.org/uniprot/A0A8C1DHW9 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/7962:LOC109099976 ^@ http://purl.uniprot.org/uniprot/A0A8C1EHN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109063194 ^@ http://purl.uniprot.org/uniprot/A0A8C1I4M3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109049853 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109059951 ^@ http://purl.uniprot.org/uniprot/A0A8C1LPT9 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/7962:LOC109071465 ^@ http://purl.uniprot.org/uniprot/A0A8C1C506 ^@ Similarity ^@ Belongs to the Arg-specific ADP-ribosyltransferase family. http://togogenome.org/gene/7962:cited4a ^@ http://purl.uniprot.org/uniprot/A0A8C1SY83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/7962:LOC109085131 ^@ http://purl.uniprot.org/uniprot/A0A8C1MCX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/7962:pth3r ^@ http://purl.uniprot.org/uniprot/A0A8C2F137 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:fyna ^@ http://purl.uniprot.org/uniprot/A0A8C1V9U7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109104781 ^@ http://purl.uniprot.org/uniprot/A0A8C2EJR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NSE2 family.|||Nucleus http://togogenome.org/gene/7962:hoatz ^@ http://purl.uniprot.org/uniprot/A0A8C1HN50 ^@ Similarity ^@ Belongs to the HOATZ family. http://togogenome.org/gene/7962:LOC109108718 ^@ http://purl.uniprot.org/uniprot/A0A8C1R891 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/7962:LOC109092368 ^@ http://purl.uniprot.org/uniprot/A0A8C2PYX5 ^@ Similarity ^@ Belongs to the NC2 beta/DR1 family. http://togogenome.org/gene/7962:LOC109108938 ^@ http://purl.uniprot.org/uniprot/A0A8C1VAI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cell membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109099568 ^@ http://purl.uniprot.org/uniprot/A0A8C1AQF4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109080931 ^@ http://purl.uniprot.org/uniprot/A0A8C1KG60 ^@ Similarity ^@ Belongs to the bZIP family. Fos subfamily. http://togogenome.org/gene/7962:npy2rl ^@ http://purl.uniprot.org/uniprot/A0A8C1A171 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:mterf2 ^@ http://purl.uniprot.org/uniprot/A0A8C1MM81 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/7962:LOC109082828 ^@ http://purl.uniprot.org/uniprot/A0A8C1IT79 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/7962:pou3f3a ^@ http://purl.uniprot.org/uniprot/A0A8C0YLE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-3 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109096707 ^@ http://purl.uniprot.org/uniprot/A0A8C1QYY8 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109046750 ^@ http://purl.uniprot.org/uniprot/A0A8C1HP23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family. GDNF subfamily.|||Secreted http://togogenome.org/gene/7962:LOC109057454 ^@ http://purl.uniprot.org/uniprot/A0A8C1B0P1 ^@ Similarity ^@ Belongs to the dickkopf family. http://togogenome.org/gene/7962:LOC109068578 ^@ http://purl.uniprot.org/uniprot/A0A8C1EBU5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:rhbdl2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/7962:ccdc172 ^@ http://purl.uniprot.org/uniprot/A0A8C1AS78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC172 family.|||Cytoplasm http://togogenome.org/gene/7962:pacsin1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FBB9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Cytoplasmic vesicle membrane|||Membrane|||cytosol|||ruffle membrane|||synaptosome http://togogenome.org/gene/7962:LOC109096999 ^@ http://purl.uniprot.org/uniprot/A0A8C1XFS7 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:dnm1b ^@ http://purl.uniprot.org/uniprot/A0A8C1B240|||http://purl.uniprot.org/uniprot/A0A8C2F4L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109089197 ^@ http://purl.uniprot.org/uniprot/A0A8C1HP68 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:hspb3 ^@ http://purl.uniprot.org/uniprot/A0A8C2D5T2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109091468 ^@ http://purl.uniprot.org/uniprot/A0A8C2FV06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109053056 ^@ http://purl.uniprot.org/uniprot/A0A8C0YAD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL27 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum http://togogenome.org/gene/7962:creb1b ^@ http://purl.uniprot.org/uniprot/A0A8C1VJJ0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109110287 ^@ http://purl.uniprot.org/uniprot/A0A8C1ATS9 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109090604 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHT8 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109081729 ^@ http://purl.uniprot.org/uniprot/A0A8C1DPD1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7962:LOC122133857 ^@ http://purl.uniprot.org/uniprot/A0A8C1DMC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMX homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109083480 ^@ http://purl.uniprot.org/uniprot/A0A8C1D9S6 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109102217 ^@ http://purl.uniprot.org/uniprot/A0A8C1YS88 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/7962:LOC109062119 ^@ http://purl.uniprot.org/uniprot/A0A8C1B720 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/7962:LOC109072788 ^@ http://purl.uniprot.org/uniprot/A0A8C1ITW3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/7962:slc25a15b ^@ http://purl.uniprot.org/uniprot/A0A8C1L975 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109111782 ^@ http://purl.uniprot.org/uniprot/A0A8C1BP67 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:pigf ^@ http://purl.uniprot.org/uniprot/A0A8C1PCS7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109083443 ^@ http://purl.uniprot.org/uniprot/A0A8C1DAQ8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109095466 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5V8|||http://purl.uniprot.org/uniprot/A0A8C1J5M6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/7962:LOC109073025 ^@ http://purl.uniprot.org/uniprot/A0A8C1DM36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted|||Somatostatin inhibits the release of somatotropin. http://togogenome.org/gene/7962:LOC109063396 ^@ http://purl.uniprot.org/uniprot/A0A8C1BY11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109053353 ^@ http://purl.uniprot.org/uniprot/A0A8C1GBH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109054931 ^@ http://purl.uniprot.org/uniprot/A0A8C1CIQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109091364 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0V0 ^@ Similarity ^@ Belongs to the TMEM14 family. http://togogenome.org/gene/7962:LOC109057608 ^@ http://purl.uniprot.org/uniprot/A0A8C1SEQ0 ^@ Function ^@ Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. http://togogenome.org/gene/7962:LOC109106248 ^@ http://purl.uniprot.org/uniprot/A0A8C1C2V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RBM8A family.|||Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.|||Cytoplasm|||Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.|||Nucleus|||Nucleus speckle http://togogenome.org/gene/7962:LOC109104018 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:LOC109055113 ^@ http://purl.uniprot.org/uniprot/A0A8C2IXG8 ^@ Function ^@ May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. http://togogenome.org/gene/7962:tpk1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKT0 ^@ Similarity ^@ Belongs to the thiamine pyrophosphokinase family. http://togogenome.org/gene/7962:LOC109066325 ^@ http://purl.uniprot.org/uniprot/A0A8C1SJH5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/7962:LOC109087725 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109095570 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKM3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/7962:LOC109066612 ^@ http://purl.uniprot.org/uniprot/A0A8C1I1C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC109107248 ^@ http://purl.uniprot.org/uniprot/A0A8C1R9W8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/7962:LOC109055076 ^@ http://purl.uniprot.org/uniprot/A0A8C1TNF0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/7962:itpkca ^@ http://purl.uniprot.org/uniprot/A0A8C1HT81 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/7962:LOC109087861 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJK2 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/7962:LOC109064127 ^@ http://purl.uniprot.org/uniprot/A0A8C1QF47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109105103 ^@ http://purl.uniprot.org/uniprot/A0A8C1AWH7 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109094142 ^@ http://purl.uniprot.org/uniprot/A0A8C1APA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADRM1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109082815 ^@ http://purl.uniprot.org/uniprot/A0A8C1D476 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/7962:dpcd ^@ http://purl.uniprot.org/uniprot/A0A8C1K451 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/7962:LOC109106858 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDM0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/7962:calhm6 ^@ http://purl.uniprot.org/uniprot/A0A8C1H0W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109057686 ^@ http://purl.uniprot.org/uniprot/A0A8C1ATX1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:capza1a ^@ http://purl.uniprot.org/uniprot/A0A8C1JE34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/7962:LOC109099746 ^@ http://purl.uniprot.org/uniprot/A0A8C2CFM2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:crygs2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLV4 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109045177 ^@ http://purl.uniprot.org/uniprot/A0A8C1BK81 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:ndufb7 ^@ http://purl.uniprot.org/uniprot/A0A8C2CB83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109079163 ^@ http://purl.uniprot.org/uniprot/A0A8C1LLZ1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109049528 ^@ http://purl.uniprot.org/uniprot/A0A8C1QF04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSG1 family.|||Membrane http://togogenome.org/gene/7962:LOC109104926 ^@ http://purl.uniprot.org/uniprot/A0A8C1GK10 ^@ Similarity ^@ Belongs to the NGF-beta family. http://togogenome.org/gene/7962:cga ^@ http://purl.uniprot.org/uniprot/P01221 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycoprotein hormones subunit alpha family.|||Heterodimer of an alpha and a beta chain.|||Involved in gametogenesis and steroidogenesis.|||Secreted http://togogenome.org/gene/7962:si:dkey-76k16.5 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y7L2 ^@ Similarity ^@ Belongs to the glycine N-acyltransferase family. http://togogenome.org/gene/7962:LOC109105778 ^@ http://purl.uniprot.org/uniprot/A0A8C2DQB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat rae1 family.|||spindle pole http://togogenome.org/gene/7962:LOC109083161 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVP6 ^@ Function ^@ Does not bind lactose, and may not bind carbohydrates. http://togogenome.org/gene/7962:pip4p1a ^@ http://purl.uniprot.org/uniprot/A0A8C2D0Y8 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:calub ^@ http://purl.uniprot.org/uniprot/A0A8C1AHD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREC family.|||Endoplasmic reticulum membrane|||Golgi apparatus|||Melanosome|||Membrane|||Sarcoplasmic reticulum lumen|||Secreted http://togogenome.org/gene/7962:LOC109064546 ^@ http://purl.uniprot.org/uniprot/A0A8C1IDG1 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/7962:LOC109091469 ^@ http://purl.uniprot.org/uniprot/A0A8C1I4J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic mitochondrial porin family.|||Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.|||Interacts with ARMC12 in a TBC1D21-dependent manner.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109112609 ^@ http://purl.uniprot.org/uniprot/A0A8C1DLX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:ppp1r14ab ^@ http://purl.uniprot.org/uniprot/A0A8C1Q023 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/7962:plbd2 ^@ http://purl.uniprot.org/uniprot/A0A8C1M2N0 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/7962:LOC109098613 ^@ http://purl.uniprot.org/uniprot/A0A8C1W3W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRK1 family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109098585 ^@ http://purl.uniprot.org/uniprot/A0A0C6EYN3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109092450 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:zfx ^@ http://purl.uniprot.org/uniprot/A0A8C1E2M7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109096974 ^@ http://purl.uniprot.org/uniprot/A0A8C1GUY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CNTF family.|||CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.|||Cytoplasm http://togogenome.org/gene/7962:cmtm8b ^@ http://purl.uniprot.org/uniprot/A0A8C0YJ13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109084598 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZVX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 6 family.|||Membrane http://togogenome.org/gene/7962:irf1b ^@ http://purl.uniprot.org/uniprot/A0A8C1RIE2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:ccn1 ^@ http://purl.uniprot.org/uniprot/A0A8C1F586 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109049058 ^@ http://purl.uniprot.org/uniprot/A0A8C1NTB5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Endoplasmic reticulum http://togogenome.org/gene/7962:LOC109086881 ^@ http://purl.uniprot.org/uniprot/A0A8C2CRK0 ^@ Similarity ^@ Belongs to the stathmin family. http://togogenome.org/gene/7962:LOC109105905 ^@ http://purl.uniprot.org/uniprot/A0A8C0YN50 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:LOC109050448 ^@ http://purl.uniprot.org/uniprot/A0A8C1B9H2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.|||Secreted http://togogenome.org/gene/7962:LOC109099616 ^@ http://purl.uniprot.org/uniprot/A0A8C1CU03|||http://purl.uniprot.org/uniprot/A0A8C1KF52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. CNC subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7962:LOC109109186 ^@ http://purl.uniprot.org/uniprot/A0A8C1C2C4 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/7962:LOC109061109 ^@ http://purl.uniprot.org/uniprot/A0A8C1C759 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109049982 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y5B2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/7962:LOC109078291 ^@ http://purl.uniprot.org/uniprot/A0A8C2A7Y4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109060351 ^@ http://purl.uniprot.org/uniprot/A0A8C1CKX6|||http://purl.uniprot.org/uniprot/A0A8C1HGX7 ^@ Similarity ^@ Belongs to the EXO5 family. http://togogenome.org/gene/7962:hoxb9a ^@ http://purl.uniprot.org/uniprot/A0A8C2K9J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109050599 ^@ http://purl.uniprot.org/uniprot/A0A8C1AEY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIII family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109071541 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109080427 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:LOC109108009 ^@ http://purl.uniprot.org/uniprot/A0A8C1JFJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109096060 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWE7|||http://purl.uniprot.org/uniprot/A0A8C2EMC8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAB family.|||Homomultimers may associate with EGR1 bound to DNA.|||Nucleus http://togogenome.org/gene/7962:LOC109054514 ^@ http://purl.uniprot.org/uniprot/A0A8C1E9G2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:popdc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1CTV7 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/7962:LOC109112001 ^@ http://purl.uniprot.org/uniprot/A0A8C1A6J9 ^@ Similarity ^@ Belongs to the requiem/DPF family. http://togogenome.org/gene/7962:LOC109064249 ^@ http://purl.uniprot.org/uniprot/A0A8C2B259 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:lamtor1 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR1 family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109047368 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family.|||Cytoplasm http://togogenome.org/gene/7962:ints11 ^@ http://purl.uniprot.org/uniprot/A0A8C1V115 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109103421 ^@ http://purl.uniprot.org/uniprot/A0A8C1C7E1 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/7962:LOC109066115 ^@ http://purl.uniprot.org/uniprot/A0A8C2JVC3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family.|||Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/7962:ube2l3b ^@ http://purl.uniprot.org/uniprot/A0A8C0XZV6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109110940 ^@ http://purl.uniprot.org/uniprot/A0A8C1FHI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shugoshin family.|||centromere http://togogenome.org/gene/7962:LOC109056203 ^@ http://purl.uniprot.org/uniprot/A0A8C1X2Y1 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109102084 ^@ http://purl.uniprot.org/uniprot/A0A8C1UC57 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109055333 ^@ http://purl.uniprot.org/uniprot/A0A8C1A745 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:gngt1 ^@ http://purl.uniprot.org/uniprot/A0A8C1QVQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:tmed1a ^@ http://purl.uniprot.org/uniprot/A0A8C1HKJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7962:LOC109056931 ^@ http://purl.uniprot.org/uniprot/A0A8C2A006 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:vps29 ^@ http://purl.uniprot.org/uniprot/A0A8C1KN50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.|||Belongs to the VPS29 family.|||Endosome membrane http://togogenome.org/gene/7962:b4gat1 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 49 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109069924 ^@ http://purl.uniprot.org/uniprot/A0A8C1CU81 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109046021 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/7962:LOC109064862 ^@ http://purl.uniprot.org/uniprot/A0A8C1L1E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Bcl-2 family.|||Membrane http://togogenome.org/gene/7962:foxa ^@ http://purl.uniprot.org/uniprot/A0A8C1B889 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:si:ch211-201o1.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADC8 ^@ Similarity ^@ Belongs to the NLRP family. http://togogenome.org/gene/7962:LOC109097381 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXD0 ^@ Similarity ^@ Belongs to the RELT family. http://togogenome.org/gene/7962:LOC109112781 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.|||Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.|||Membrane|||This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. http://togogenome.org/gene/7962:LOC109051617 ^@ http://purl.uniprot.org/uniprot/A0A8C2KC74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:LOC109105074 ^@ http://purl.uniprot.org/uniprot/A0A8C1TZ72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GAMAD family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/7962:LOC109112746 ^@ http://purl.uniprot.org/uniprot/A0A8C1LZB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CD164 family.|||Membrane http://togogenome.org/gene/7962:LOC109091746 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGE9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/7962:LOC109100756 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJ60 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:lgi2b ^@ http://purl.uniprot.org/uniprot/A0A8C1I488 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109065729 ^@ http://purl.uniprot.org/uniprot/A0A8C1F0N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/7962:LOC109085104 ^@ http://purl.uniprot.org/uniprot/A0A8C1DE98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDI family.|||Cytoplasm|||Endosome|||Nucleus http://togogenome.org/gene/7962:LOC109070928 ^@ http://purl.uniprot.org/uniprot/A0A8C1I1N4 ^@ Similarity ^@ Belongs to the MS4A family. http://togogenome.org/gene/7962:LOC109084694 ^@ http://purl.uniprot.org/uniprot/A0A8C1KQ15 ^@ Similarity ^@ Belongs to the protease inhibitor I35 (TIMP) family. http://togogenome.org/gene/7962:LOC109097501 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/7962:LOC109075628 ^@ http://purl.uniprot.org/uniprot/A0A8C1LZ95 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/7962:LOC109094725 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q3Z9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:dbx1b ^@ http://purl.uniprot.org/uniprot/A0A8C1IIP3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062105 ^@ http://purl.uniprot.org/uniprot/A0A8C1EDN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL42 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109058628 ^@ http://purl.uniprot.org/uniprot/A0A8C1CGG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109097262 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:lpar2a ^@ http://purl.uniprot.org/uniprot/A0A8C1JUG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cell surface|||Endosome|||Membrane http://togogenome.org/gene/7962:LOC109067341 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSA6 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/7962:LOC109056839 ^@ http://purl.uniprot.org/uniprot/A0A8C1H7R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109064654 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCC4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:ppp2r5a ^@ http://purl.uniprot.org/uniprot/A0A8C1P2E5 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/7962:gcga ^@ http://purl.uniprot.org/uniprot/A0A8C1EE09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/7962:LOC109066313 ^@ http://purl.uniprot.org/uniprot/A0A8C1NUL4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:gabarapa ^@ http://purl.uniprot.org/uniprot/A0A8C1BBM1 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109105902 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDG6 ^@ Function|||Subcellular Location Annotation ^@ General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.|||Golgi apparatus|||Membrane|||Mitochondrion http://togogenome.org/gene/7962:traf4b ^@ http://purl.uniprot.org/uniprot/A0A8C2KZQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family.|||Cytoplasm http://togogenome.org/gene/7962:wnt11 ^@ http://purl.uniprot.org/uniprot/A0A8C1BL44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109049945 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/7962:LOC109048598 ^@ http://purl.uniprot.org/uniprot/A0A8C1H785 ^@ Subunit ^@ Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling. http://togogenome.org/gene/7962:si:ch211-260e23.8 ^@ http://purl.uniprot.org/uniprot/A0A8C1K9T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the C19orf12 family.|||Mitochondrion membrane http://togogenome.org/gene/7962:LOC109076266 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109101010 ^@ http://purl.uniprot.org/uniprot/A0A8C0YGY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/7962:LOC109064947 ^@ http://purl.uniprot.org/uniprot/A0A8C1WAN0 ^@ Similarity ^@ Belongs to the UPF0430 family. http://togogenome.org/gene/7962:LOC109063073 ^@ http://purl.uniprot.org/uniprot/A0A8C1DTH0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109054111 ^@ http://purl.uniprot.org/uniprot/A0A089ZZX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Membrane http://togogenome.org/gene/7962:LOC109068564 ^@ http://purl.uniprot.org/uniprot/A0A8C1CU11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase T2 family.|||Lysosome lumen http://togogenome.org/gene/7962:LOC109081219 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Lipocalin family.|||Secreted http://togogenome.org/gene/7962:LOC109078327 ^@ http://purl.uniprot.org/uniprot/A0A8C1PJR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:imp4 ^@ http://purl.uniprot.org/uniprot/A0A8C2EYL4 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109089166 ^@ http://purl.uniprot.org/uniprot/A0A8C1FSV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:LOC109055942 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:LOC109104475 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0I2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:tmem116 ^@ http://purl.uniprot.org/uniprot/A0A8C1DSE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:ppp1r3cb ^@ http://purl.uniprot.org/uniprot/A0A8C1KIT7 ^@ Domain|||Function|||Subunit ^@ Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.|||Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.|||The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase. http://togogenome.org/gene/7962:LOC109069698 ^@ http://purl.uniprot.org/uniprot/A0A8C1C797 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the translin family.|||DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.|||Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.|||Nucleus|||Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring. http://togogenome.org/gene/7962:LOC109058286 ^@ http://purl.uniprot.org/uniprot/A0A8C1IWV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/7962:LOC109111445 ^@ http://purl.uniprot.org/uniprot/A0A8C1F4I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/7962:LOC109105958 ^@ http://purl.uniprot.org/uniprot/A0A8C1BN84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109111761 ^@ http://purl.uniprot.org/uniprot/A0A8C1R7R0 ^@ Similarity ^@ Belongs to the SYCE family. http://togogenome.org/gene/7962:LOC109076181 ^@ http://purl.uniprot.org/uniprot/I6MS43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109113528 ^@ http://purl.uniprot.org/uniprot/A0A8C1JDR3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:spcs1 ^@ http://purl.uniprot.org/uniprot/A0A8C1JAA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:cd37 ^@ http://purl.uniprot.org/uniprot/A0A8C2GNK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109049929 ^@ http://purl.uniprot.org/uniprot/A0A8C2A8C0 ^@ Function|||Similarity ^@ Belongs to the SMPX family.|||Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. http://togogenome.org/gene/7962:ttc4 ^@ http://purl.uniprot.org/uniprot/A0A8C1C9H0 ^@ Similarity ^@ Belongs to the TTC4 family. http://togogenome.org/gene/7962:LOC109099552 ^@ http://purl.uniprot.org/uniprot/A0A8C2KYI2 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/7962:cnn1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FF26 ^@ Function|||Similarity ^@ Belongs to the calponin family.|||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. http://togogenome.org/gene/7962:LOC109101505 ^@ http://purl.uniprot.org/uniprot/A0A8C1LQZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109073861 ^@ http://purl.uniprot.org/uniprot/A0A8C1EP23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:KEF38_p13 ^@ http://purl.uniprot.org/uniprot/P24969 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 1 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109052329 ^@ http://purl.uniprot.org/uniprot/A0A8C2ATE3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:foxf1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ESL6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109081231 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZ11 ^@ Subcellular Location Annotation ^@ nucleoplasm http://togogenome.org/gene/7962:LOC109104641 ^@ http://purl.uniprot.org/uniprot/A0A8C1CV47|||http://purl.uniprot.org/uniprot/A0A8C1GHP9 ^@ Similarity ^@ Belongs to the synaptotagmin family. http://togogenome.org/gene/7962:cldng ^@ http://purl.uniprot.org/uniprot/A0A8C2DAR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109080434 ^@ http://purl.uniprot.org/uniprot/A0A8C1EEM0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/7962:LOC109105817 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6Z4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:kctd3 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y9T8 ^@ Similarity ^@ Belongs to the KCTD3 family. http://togogenome.org/gene/7962:LOC109101489 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:pias4b ^@ http://purl.uniprot.org/uniprot/A0A8C1BTX3 ^@ Similarity ^@ Belongs to the PIAS family. http://togogenome.org/gene/7962:LOC109073367 ^@ http://purl.uniprot.org/uniprot/A0A8C1PF56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/7962:LOC109053059 ^@ http://purl.uniprot.org/uniprot/A0A8C1I8N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109057478 ^@ http://purl.uniprot.org/uniprot/A0A8C1CF02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARMET family.|||Secreted http://togogenome.org/gene/7962:LOC109047169 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANY6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109085600 ^@ http://purl.uniprot.org/uniprot/A0A8C1DDT6 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:opn4.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1JHH7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109074671 ^@ http://purl.uniprot.org/uniprot/Q70V43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109055146 ^@ http://purl.uniprot.org/uniprot/A0A8C1KML5 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/7962:LOC109073849 ^@ http://purl.uniprot.org/uniprot/A0A8C2GGL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109059694 ^@ http://purl.uniprot.org/uniprot/A0A8C1NU50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Membrane http://togogenome.org/gene/7962:LOC109051886 ^@ http://purl.uniprot.org/uniprot/A0A8C1C403 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.|||May play a role in motor coordination and exploratory behavior. http://togogenome.org/gene/7962:LOC109113693 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q183 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gastrin/cholecystokinin family.|||Secreted http://togogenome.org/gene/7962:marveld2b ^@ http://purl.uniprot.org/uniprot/A0A8C0Y340 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELL/occludin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC122134046 ^@ http://purl.uniprot.org/uniprot/A0A8C1B924|||http://purl.uniprot.org/uniprot/A0A8C1MEK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/7962:LOC109104712 ^@ http://purl.uniprot.org/uniprot/A0A8C1RNA7 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/7962:LOC109067953 ^@ http://purl.uniprot.org/uniprot/A0A8C2E120 ^@ Function ^@ Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. http://togogenome.org/gene/7962:LOC109067531 ^@ http://purl.uniprot.org/uniprot/A0A8C1C8I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109090312 ^@ http://purl.uniprot.org/uniprot/A0A8C1CP07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. http://togogenome.org/gene/7962:gabra5 ^@ http://purl.uniprot.org/uniprot/A0A8C1KF09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:adipor2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109100056 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZPV4 ^@ Subcellular Location Annotation ^@ Apical cell membrane|||Cell membrane|||Lipid droplet http://togogenome.org/gene/7962:isl2a ^@ http://purl.uniprot.org/uniprot/A0A8C1NDZ3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:hoxd9a ^@ http://purl.uniprot.org/uniprot/A0A8C1ESI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109050611 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y884 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109103265 ^@ http://purl.uniprot.org/uniprot/A0A8C1N3P1 ^@ Subcellular Location Annotation ^@ centriole|||cilium|||cis-Golgi network http://togogenome.org/gene/7962:pla2g15 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5U0 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/7962:pigx ^@ http://purl.uniprot.org/uniprot/A0A8C1H6P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGX family.|||Endoplasmic reticulum membrane|||Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. http://togogenome.org/gene/7962:gng2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BUT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109090461 ^@ http://purl.uniprot.org/uniprot/A0A8C2GJU9 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/7962:abraxas2 ^@ http://purl.uniprot.org/uniprot/A0A8C1DM73 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109056282 ^@ http://purl.uniprot.org/uniprot/A0A8C1JL45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109055565 ^@ http://purl.uniprot.org/uniprot/A0A8C1CF38 ^@ Similarity ^@ Belongs to the costars family. http://togogenome.org/gene/7962:LOC109088000 ^@ http://purl.uniprot.org/uniprot/A0A8C1E1Q7|||http://purl.uniprot.org/uniprot/A0A8C1HS57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GGA protein family.|||Early endosome membrane|||Endosome membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109098561 ^@ http://purl.uniprot.org/uniprot/A0A8C2A9N1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109046543 ^@ http://purl.uniprot.org/uniprot/A0A8C1CL90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M14 family.|||Membrane|||secretory vesicle membrane http://togogenome.org/gene/7962:LOC109088191 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q4U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-alpha family. G(12) subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109083915 ^@ http://purl.uniprot.org/uniprot/A0A8C1P378 ^@ Subcellular Location Annotation ^@ Inflammasome http://togogenome.org/gene/7962:LOC109064153 ^@ http://purl.uniprot.org/uniprot/A0A8C1B6U7 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:LOC109050745 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109097919 ^@ http://purl.uniprot.org/uniprot/A0A8C1HCC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/7962:desi1b ^@ http://purl.uniprot.org/uniprot/A0A8C2KD75 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/7962:LOC109102539 ^@ http://purl.uniprot.org/uniprot/A0A8C1MWL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109099160 ^@ http://purl.uniprot.org/uniprot/A0A8C1DBB5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109070422 ^@ http://purl.uniprot.org/uniprot/A0A8C1GPT7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:lyrm5b ^@ http://purl.uniprot.org/uniprot/A0A8C1JVE7 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/7962:LOC109057851 ^@ http://purl.uniprot.org/uniprot/A0A8C1PXB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/7962:chrm4a ^@ http://purl.uniprot.org/uniprot/A0A8C1EHM9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. http://togogenome.org/gene/7962:paqr3b ^@ http://purl.uniprot.org/uniprot/A0A8C1CGD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/7962:LOC109104985 ^@ http://purl.uniprot.org/uniprot/A0A8C0YVA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TYROBP family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109051831 ^@ http://purl.uniprot.org/uniprot/A0A8C1CBC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:foxd5 ^@ http://purl.uniprot.org/uniprot/A0A8C1C307 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:odr4 ^@ http://purl.uniprot.org/uniprot/A0A8C1AQF0 ^@ Function|||Similarity ^@ Belongs to the ODR-4 family.|||May play a role in the trafficking of a subset of G-protein coupled receptors. http://togogenome.org/gene/7962:LOC109096973 ^@ http://purl.uniprot.org/uniprot/A0A8C2B3A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CNTF family.|||CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.|||Cytoplasm http://togogenome.org/gene/7962:LOC109110020 ^@ http://purl.uniprot.org/uniprot/A0A8C1CFP2 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/7962:LOC109113338 ^@ http://purl.uniprot.org/uniprot/A0A8C1G253 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109099409 ^@ http://purl.uniprot.org/uniprot/A0A8C1SEU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||May be involved in fusion of ER-derived transport vesicles with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:LOC109094664 ^@ http://purl.uniprot.org/uniprot/A0A8C2CAE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:LOC109079486 ^@ http://purl.uniprot.org/uniprot/P10112 ^@ Domain|||Function|||Similarity ^@ Belongs to the beta/gamma-crystallin family.|||Crystallins are the dominant structural components of the vertebrate eye lens.|||Has a two-domain beta-structure, folded into four very similar Greek key motifs. http://togogenome.org/gene/7962:LOC109052886 ^@ http://purl.uniprot.org/uniprot/A0A8C1GYG9 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.|||Nucleus http://togogenome.org/gene/7962:tent5ab ^@ http://purl.uniprot.org/uniprot/A0A8C1BCJ4 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/7962:tmem14a ^@ http://purl.uniprot.org/uniprot/A0A8C1XYD2 ^@ Similarity ^@ Belongs to the TMEM14 family. http://togogenome.org/gene/7962:LOC109104617 ^@ http://purl.uniprot.org/uniprot/A0A8C1CRA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gastrin/cholecystokinin family.|||Secreted http://togogenome.org/gene/7962:LOC109058907 ^@ http://purl.uniprot.org/uniprot/A0A8C1STH8|||http://purl.uniprot.org/uniprot/A0A8C2LAH8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nuclear hormone receptor family. NR2 subfamily.|||Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.|||Homodimer. Heterodimer; with a rar molecule.|||Nucleus|||Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. http://togogenome.org/gene/7962:LOC109048780 ^@ http://purl.uniprot.org/uniprot/A0A8C1B7F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109053916 ^@ http://purl.uniprot.org/uniprot/A0A8C1AX40 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/7962:zgc:165573 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYSTM1 family.|||Membrane http://togogenome.org/gene/7962:LOC109090660 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKS9 ^@ Function|||Subcellular Location Annotation ^@ Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/7962:LOC109103091 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZDM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. http://togogenome.org/gene/7962:LOC109045130 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family. Bicoid subfamily.|||Nucleus|||Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. http://togogenome.org/gene/7962:LOC109063043 ^@ http://purl.uniprot.org/uniprot/A0A8C1DNF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:LOC109070210 ^@ http://purl.uniprot.org/uniprot/A0A8C1ELU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endosulfine family.|||Cytoplasm|||Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. http://togogenome.org/gene/7962:LOC109082167 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. http://togogenome.org/gene/7962:LOC109051343 ^@ http://purl.uniprot.org/uniprot/A0A8C1E7T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Chromosome|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/7962:LOC109066371 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6Y7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/7962:LOC109100786 ^@ http://purl.uniprot.org/uniprot/A0A8C1VXB8 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/7962:LOC109051906 ^@ http://purl.uniprot.org/uniprot/A0A8C1C7N5 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/7962:LOC109057782 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR72 ^@ Similarity ^@ Belongs to the apolipoprotein A1/A4/E family. http://togogenome.org/gene/7962:LOC109087991 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0I0 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:olah ^@ http://purl.uniprot.org/uniprot/A0A8C1BTJ8 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/7962:LOC109079878 ^@ http://purl.uniprot.org/uniprot/A0A8C2A744 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/7962:LOC109088202 ^@ http://purl.uniprot.org/uniprot/A0A8C1EY05|||http://purl.uniprot.org/uniprot/A0A8C1F2I9 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/7962:nprl3 ^@ http://purl.uniprot.org/uniprot/A0A8C1DIT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.|||Belongs to the NPR3 family.|||Lysosome http://togogenome.org/gene/7962:LOC109099608 ^@ http://purl.uniprot.org/uniprot/A0A8C1PAP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109056620 ^@ http://purl.uniprot.org/uniprot/A0A7T7DMF0 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:mlec ^@ http://purl.uniprot.org/uniprot/A0A8C2EPR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the malectin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:msmp2 ^@ http://purl.uniprot.org/uniprot/A0A8C1BR81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-microseminoprotein family.|||Secreted http://togogenome.org/gene/7962:LOC109082281 ^@ http://purl.uniprot.org/uniprot/A0A8C2AEH5 ^@ Subcellular Location Annotation ^@ Chromosome|||Cytoplasm http://togogenome.org/gene/7962:LOC109102865 ^@ http://purl.uniprot.org/uniprot/A0A8C1R1C2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/7962:LOC109069048 ^@ http://purl.uniprot.org/uniprot/A0A8C1BSI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.|||Secreted http://togogenome.org/gene/7962:LOC109059920 ^@ http://purl.uniprot.org/uniprot/A0A8C1SS50 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/7962:LOC109091667 ^@ http://purl.uniprot.org/uniprot/A0A8C1C9B2 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/7962:pex19 ^@ http://purl.uniprot.org/uniprot/A0A8C1D0Y8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxin-19 family.|||Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.|||Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.|||Peroxisome membrane http://togogenome.org/gene/7962:LOC109071418 ^@ http://purl.uniprot.org/uniprot/A0A8C1C3K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexin family.|||Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/7962:LOC109107725 ^@ http://purl.uniprot.org/uniprot/A0A8C1E2B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109052090 ^@ http://purl.uniprot.org/uniprot/A0A8C0YCE1 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/7962:crygmxl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1GL83 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109096150 ^@ http://purl.uniprot.org/uniprot/A0A8C1YGB2 ^@ Similarity ^@ Belongs to the UPF0524 family. http://togogenome.org/gene/7962:LOC109072242 ^@ http://purl.uniprot.org/uniprot/A0A8C1NK04 ^@ Similarity ^@ Belongs to the SZRD1 family. http://togogenome.org/gene/7962:LOC109088896 ^@ http://purl.uniprot.org/uniprot/A0A8C1FJR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.|||centrosome http://togogenome.org/gene/7962:LOC109100227 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLU8|||http://purl.uniprot.org/uniprot/A0A8C1A4Z8 ^@ Function|||Similarity ^@ Belongs to the RutC family.|||Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. http://togogenome.org/gene/7962:zgc:101583 ^@ http://purl.uniprot.org/uniprot/A0A8C1CFT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/7962:stx12 ^@ http://purl.uniprot.org/uniprot/A0A8C1HYJ3 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109059937 ^@ http://purl.uniprot.org/uniprot/A0A8C1CJ90 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/7962:hbp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BLN6 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. http://togogenome.org/gene/7962:LOC109100940 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEY7 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/7962:LOC109094043 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZC6 ^@ Function|||Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.|||Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. http://togogenome.org/gene/7962:cygb1 ^@ http://purl.uniprot.org/uniprot/M4QW49 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109110756 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109104939 ^@ http://purl.uniprot.org/uniprot/A0A8C0YI68 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062689 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109111740 ^@ http://purl.uniprot.org/uniprot/A0A8C1GVR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/7962:mc5ra ^@ http://purl.uniprot.org/uniprot/Q683Z6|||http://purl.uniprot.org/uniprot/Q683Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. http://togogenome.org/gene/7962:ska1 ^@ http://purl.uniprot.org/uniprot/A0A8C1E2Q6 ^@ Similarity ^@ Belongs to the SKA1 family. http://togogenome.org/gene/7962:LOC109111086 ^@ http://purl.uniprot.org/uniprot/A0A8C2A4J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS7 family.|||Membrane http://togogenome.org/gene/7962:LOC109094495 ^@ http://purl.uniprot.org/uniprot/A0A8C1MCR6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109065573 ^@ http://purl.uniprot.org/uniprot/A0A8C1BTS3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:ndr1 ^@ http://purl.uniprot.org/uniprot/A0A8C1A401 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:nadk2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD kinase family.|||Homodimer.|||Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.|||Mitochondrion http://togogenome.org/gene/7962:LOC109110941 ^@ http://purl.uniprot.org/uniprot/A0A8C2I192 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/7962:plac8.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1FHX6 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:hbaa2 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y6M0 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109081033 ^@ http://purl.uniprot.org/uniprot/A0A8C1GTI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109074882 ^@ http://purl.uniprot.org/uniprot/A0A8C1RUL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/7962:LOC109074382 ^@ http://purl.uniprot.org/uniprot/A0A8C1ET22 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the PA-phosphatase related phosphoesterase family.|||Cell membrane|||Membrane|||Membrane raft|||caveola http://togogenome.org/gene/7962:LOC109104187 ^@ http://purl.uniprot.org/uniprot/A0A8C1CY76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:smim12 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPT5 ^@ Similarity ^@ Belongs to the SMIM12 family. http://togogenome.org/gene/7962:LOC109068128 ^@ http://purl.uniprot.org/uniprot/A0A8C1BF37 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:slc48a1b ^@ http://purl.uniprot.org/uniprot/A0A8C1E5K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HRG family.|||Endosome membrane|||Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109095246 ^@ http://purl.uniprot.org/uniprot/A0A8C1MUD1 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:LOC109111854 ^@ http://purl.uniprot.org/uniprot/A0A8C0YSR5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Lipid droplet|||caveola|||cytosol http://togogenome.org/gene/7962:LOC109094537 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDP6 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109052246 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INKA family.|||Nucleus http://togogenome.org/gene/7962:LOC109096545 ^@ http://purl.uniprot.org/uniprot/A0A8C1BRD7 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/7962:LOC109062476 ^@ http://purl.uniprot.org/uniprot/A0A8C1NJ19 ^@ Similarity ^@ Belongs to the TMEM70 family. http://togogenome.org/gene/7962:LOC109088656 ^@ http://purl.uniprot.org/uniprot/A0A8C1FGK5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:tac1 ^@ http://purl.uniprot.org/uniprot/A0A8C2EHY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tachykinin family.|||Secreted|||Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. http://togogenome.org/gene/7962:LOC109057286 ^@ http://purl.uniprot.org/uniprot/A0A8C1HXZ1 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7962:mycla ^@ http://purl.uniprot.org/uniprot/A0A8C1MX94 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.|||Nucleus http://togogenome.org/gene/7962:LOC109104965 ^@ http://purl.uniprot.org/uniprot/A0A8C0YRW2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/7962:sec22ba ^@ http://purl.uniprot.org/uniprot/A0A8C1L5W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109052559 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJ16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/7962:zgpat ^@ http://purl.uniprot.org/uniprot/A0A8C1BDC1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:six2a ^@ http://purl.uniprot.org/uniprot/A0A8C1VIC2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109087329 ^@ http://purl.uniprot.org/uniprot/A0A8C1NFG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109100934 ^@ http://purl.uniprot.org/uniprot/A0A8C1DEW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.|||Nucleus http://togogenome.org/gene/7962:tp53rk ^@ http://purl.uniprot.org/uniprot/A0A8C1CUM1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/7962:LOC109092901 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5M1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109068264 ^@ http://purl.uniprot.org/uniprot/A0A8C1QM79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus|||The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. http://togogenome.org/gene/7962:adgrl4 ^@ http://purl.uniprot.org/uniprot/A0A8C1HZN0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109102184 ^@ http://purl.uniprot.org/uniprot/A0A8C1DRE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the securin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109049059 ^@ http://purl.uniprot.org/uniprot/A0A8C1H749 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109109998 ^@ http://purl.uniprot.org/uniprot/A0A8C2BWQ0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/7962:hoxd12a ^@ http://purl.uniprot.org/uniprot/A0A8C1EW68 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109055489 ^@ http://purl.uniprot.org/uniprot/A0A8C1B565 ^@ Similarity ^@ Belongs to the BLOC1S2 family. http://togogenome.org/gene/7962:LOC109091582 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6T8 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:LOC109099507 ^@ http://purl.uniprot.org/uniprot/A0A8C1KQ06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HARBI1 family.|||Cytoplasm|||Nucleus|||Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. http://togogenome.org/gene/7962:LOC109074798 ^@ http://purl.uniprot.org/uniprot/A0A0M4TZQ6 ^@ Similarity ^@ Belongs to the GST superfamily. Kappa family. http://togogenome.org/gene/7962:LOC109078095 ^@ http://purl.uniprot.org/uniprot/A0A8C1SJP6 ^@ Similarity ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. http://togogenome.org/gene/7962:LOC109104640 ^@ http://purl.uniprot.org/uniprot/A0A8C1CXF2 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily. http://togogenome.org/gene/7962:LOC109065739 ^@ http://purl.uniprot.org/uniprot/A0A8C1M0X3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/7962:LOC109089351 ^@ http://purl.uniprot.org/uniprot/A0A8C1B3G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:lgalslb ^@ http://purl.uniprot.org/uniprot/A0A8C2KPH8 ^@ Function ^@ Does not bind lactose, and may not bind carbohydrates. http://togogenome.org/gene/7962:LOC109072270 ^@ http://purl.uniprot.org/uniprot/A0A8C1ETV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/7962:nedd8 ^@ http://purl.uniprot.org/uniprot/A0A8C2AWE5 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/7962:LOC109057059 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPF2 ^@ Similarity ^@ Belongs to the NATD1 family. http://togogenome.org/gene/7962:LOC109110984 ^@ http://purl.uniprot.org/uniprot/A0A8C1H6C9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family.|||Early endosome|||Endosome|||May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.|||perinuclear region http://togogenome.org/gene/7962:gja5b ^@ http://purl.uniprot.org/uniprot/A0A8C1DUM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109104700 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZMJ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sdhaf1 ^@ http://purl.uniprot.org/uniprot/A0A8C1GC59 ^@ Similarity ^@ Belongs to the complex I LYR family. SDHAF1 subfamily. http://togogenome.org/gene/7962:LOC109092287 ^@ http://purl.uniprot.org/uniprot/A0A8C1GKB6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109105730 ^@ http://purl.uniprot.org/uniprot/A0A8C0YF99 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:pthlhb ^@ http://purl.uniprot.org/uniprot/A0A8C0YI37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||Secreted http://togogenome.org/gene/7962:LOC109109111 ^@ http://purl.uniprot.org/uniprot/A0A8C1WVY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109068946 ^@ http://purl.uniprot.org/uniprot/A0A8C1CI58 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109093690 ^@ http://purl.uniprot.org/uniprot/A0A8C1HGY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RETREG family.|||Membrane http://togogenome.org/gene/7962:tlcd5a ^@ http://purl.uniprot.org/uniprot/A0A8C1RB99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109093513 ^@ http://purl.uniprot.org/uniprot/A0A8C0YJT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked.|||Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales. http://togogenome.org/gene/7962:LOC109093902 ^@ http://purl.uniprot.org/uniprot/A0A8C1AW92 ^@ Similarity ^@ Belongs to the apolipoprotein L family. http://togogenome.org/gene/7962:LOC109076465 ^@ http://purl.uniprot.org/uniprot/A0A8C1B740 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109102438 ^@ http://purl.uniprot.org/uniprot/A0A8C2FCV3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/7962:LOC109110722 ^@ http://purl.uniprot.org/uniprot/A0A173M1X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-17 family.|||Secreted http://togogenome.org/gene/7962:LOC109058818 ^@ http://purl.uniprot.org/uniprot/A0A8C1CV20 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109081702 ^@ http://purl.uniprot.org/uniprot/A0A8C1GMZ1 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/7962:LOC109095189 ^@ http://purl.uniprot.org/uniprot/A0A8C1RIB2 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/7962:LOC109104750 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y8K2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/7962:timm8b ^@ http://purl.uniprot.org/uniprot/A0A8C1GVN5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7962:LOC109048054 ^@ http://purl.uniprot.org/uniprot/A0A8C1CCU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab GDI family.|||Cytoplasm|||Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. http://togogenome.org/gene/7962:si:dkey-51e6.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1GJY4 ^@ Similarity ^@ Belongs to the janus family. http://togogenome.org/gene/7962:LOC109105954 ^@ http://purl.uniprot.org/uniprot/A0A8C1R662 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/7962:lss ^@ http://purl.uniprot.org/uniprot/A0A8C1FZK2 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/7962:LOC109104189 ^@ http://purl.uniprot.org/uniprot/A0A8C1CZB4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C19 family. USP16 subfamily.|||Homotetramer.|||Nucleus|||Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.|||The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin. http://togogenome.org/gene/7962:LOC109090286 ^@ http://purl.uniprot.org/uniprot/A0A8C1MDX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C48 family.|||nucleolus http://togogenome.org/gene/7962:LOC109072338 ^@ http://purl.uniprot.org/uniprot/A0A8C1GIG9 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:spi2 ^@ http://purl.uniprot.org/uniprot/A0A8C1EPF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:LOC109072697 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5Z1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Interacts with PEX19.|||Peroxisome membrane http://togogenome.org/gene/7962:LOC109053745 ^@ http://purl.uniprot.org/uniprot/A0A8C1DTW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/7962:LOC109077584 ^@ http://purl.uniprot.org/uniprot/A0A8C1PVA6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109062888 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:gng12a ^@ http://purl.uniprot.org/uniprot/A0A8C1Q2J8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109075374 ^@ http://purl.uniprot.org/uniprot/A0A8C1VL13 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/7962:LOC109075433 ^@ http://purl.uniprot.org/uniprot/A0A8C1GGD9|||http://purl.uniprot.org/uniprot/A0A8C1UB44 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109079157 ^@ http://purl.uniprot.org/uniprot/A0A8C1NQA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM241 family.|||Membrane http://togogenome.org/gene/7962:LOC109062722 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQ11|||http://purl.uniprot.org/uniprot/A0A8C1FYS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/7962:rps6 ^@ http://purl.uniprot.org/uniprot/A0A8C2EJM4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/7962:LOC109052741 ^@ http://purl.uniprot.org/uniprot/A0A8C2FAT7 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/7962:ssbp2a ^@ http://purl.uniprot.org/uniprot/A0A8C1KFC3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:atp5pb ^@ http://purl.uniprot.org/uniprot/A0A8C1YDD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109070100 ^@ http://purl.uniprot.org/uniprot/A0A8C1EH75 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/7962:spon2b ^@ http://purl.uniprot.org/uniprot/A0A8C1LWN6 ^@ Subcellular Location Annotation ^@ extracellular matrix http://togogenome.org/gene/7962:hnrnph1l ^@ http://purl.uniprot.org/uniprot/A0A8C0Y773 ^@ Subcellular Location Annotation ^@ nucleoplasm http://togogenome.org/gene/7962:LOC109109798 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP92 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109071874 ^@ http://purl.uniprot.org/uniprot/A0A8C1KZ97 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/7962:gpkow ^@ http://purl.uniprot.org/uniprot/A0A8C1FPV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MOS2 family.|||Nucleus http://togogenome.org/gene/7962:neil1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ELG8 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/7962:LOC109087136 ^@ http://purl.uniprot.org/uniprot/A0A8C1HRR5 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/7962:prph2a ^@ http://purl.uniprot.org/uniprot/A0A8C1AAQ4 ^@ Similarity ^@ Belongs to the PRPH2/ROM1 family. http://togogenome.org/gene/7962:LOC109065252 ^@ http://purl.uniprot.org/uniprot/A0A8C1LWG2 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/7962:LOC109087626 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLE2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. RGK family. http://togogenome.org/gene/7962:LOC109101395 ^@ http://purl.uniprot.org/uniprot/A0A8C2PQY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:msx1b ^@ http://purl.uniprot.org/uniprot/A0A8C1Z4M6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:im:7138535 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYR1 ^@ Similarity ^@ Belongs to the FAM98 family. http://togogenome.org/gene/7962:LOC109069501 ^@ http://purl.uniprot.org/uniprot/A0A8C1FHK9 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109057803 ^@ http://purl.uniprot.org/uniprot/A0A8C1L309 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/7962:lyrm7 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.|||Belongs to the complex I LYR family.|||Interacts with UQCRFS1.|||Mitochondrion matrix http://togogenome.org/gene/7962:LOC109063224 ^@ http://purl.uniprot.org/uniprot/A0A8C1JZ47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GOSR2 family.|||Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.|||Membrane http://togogenome.org/gene/7962:LOC109104119 ^@ http://purl.uniprot.org/uniprot/A0A8C1KE29|||http://purl.uniprot.org/uniprot/A0A8C1KI54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tango11 family.|||Membrane|||Mitochondrion outer membrane|||Peroxisome|||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. http://togogenome.org/gene/7962:tspan18a ^@ http://purl.uniprot.org/uniprot/A0A8C1HF77|||http://purl.uniprot.org/uniprot/A0A8C1T226 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109092886 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109093589 ^@ http://purl.uniprot.org/uniprot/A0A8C0YG94 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109046511 ^@ http://purl.uniprot.org/uniprot/A0A8C1QZN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/7962:LOC109078023 ^@ http://purl.uniprot.org/uniprot/A0A8C1UEM9 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/7962:KEF38_p09 ^@ http://purl.uniprot.org/uniprot/P24948|||http://purl.uniprot.org/uniprot/Q5UVT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase protein 8 family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).|||Mitochondrion membrane http://togogenome.org/gene/7962:efemp2a ^@ http://purl.uniprot.org/uniprot/A0A8C1AYE5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:bud23 ^@ http://purl.uniprot.org/uniprot/A0A8C1RU20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109059527 ^@ http://purl.uniprot.org/uniprot/A0A8C1R9D0 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:si:dkey-22f5.9 ^@ http://purl.uniprot.org/uniprot/A0A8C1SSB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LEAP2 family.|||Has an antimicrobial activity.|||Secreted http://togogenome.org/gene/7962:eno1b ^@ http://purl.uniprot.org/uniprot/A0A8C1FUH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109058357 ^@ http://purl.uniprot.org/uniprot/A0A8C1VEY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/7962:LOC109073465 ^@ http://purl.uniprot.org/uniprot/A0A8C1WNP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/7962:LOC109056541 ^@ http://purl.uniprot.org/uniprot/A0A8C1AT19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/7962:LOC109087083 ^@ http://purl.uniprot.org/uniprot/A0A0M3VGN5 ^@ Similarity ^@ Belongs to the GST superfamily. Mu family. http://togogenome.org/gene/7962:LOC109050403 ^@ http://purl.uniprot.org/uniprot/A0A8C0YG65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7962:LOC109113569 ^@ http://purl.uniprot.org/uniprot/A0A8C2FD41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Secreted http://togogenome.org/gene/7962:mdkb ^@ http://purl.uniprot.org/uniprot/A0A8C2I7W5 ^@ Similarity ^@ Belongs to the pleiotrophin family. http://togogenome.org/gene/7962:mrpl49 ^@ http://purl.uniprot.org/uniprot/A0A8C1C4Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/7962:serpinh2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YBU1 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:lhfpl2a ^@ http://purl.uniprot.org/uniprot/A0A8C1CC74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109061232 ^@ http://purl.uniprot.org/uniprot/A0A8C1KHS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109074924 ^@ http://purl.uniprot.org/uniprot/A0A8C1GVD4 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/7962:LOC109095329 ^@ http://purl.uniprot.org/uniprot/A0A8C1AV80|||http://purl.uniprot.org/uniprot/S5RKA2 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109074819 ^@ http://purl.uniprot.org/uniprot/A0A8C1INU1 ^@ Similarity ^@ Belongs to the IL-17 family. http://togogenome.org/gene/7962:LOC109105910 ^@ http://purl.uniprot.org/uniprot/A0A8C1A658 ^@ Subcellular Location Annotation ^@ PML body|||autophagosome|||cytosol http://togogenome.org/gene/7962:LOC109100350 ^@ http://purl.uniprot.org/uniprot/A0A8C1SV12 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109107093 ^@ http://purl.uniprot.org/uniprot/A0A8C1E3V8 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/7962:LOC109051350 ^@ http://purl.uniprot.org/uniprot/A0A8C1WBK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:LOC109111080 ^@ http://purl.uniprot.org/uniprot/A0A8C1AAI2 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/7962:LOC109078877 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKI4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:tmem39a ^@ http://purl.uniprot.org/uniprot/A0A8C1PLI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM39 family.|||Membrane http://togogenome.org/gene/7962:hnrnph1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C6H0|||http://purl.uniprot.org/uniprot/A0A8C1S4B8 ^@ Subcellular Location Annotation ^@ nucleoplasm http://togogenome.org/gene/7962:LOC109060744 ^@ http://purl.uniprot.org/uniprot/A0A8C1DP21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM54 family.|||Membrane http://togogenome.org/gene/7962:LOC109085942 ^@ http://purl.uniprot.org/uniprot/A0A8C1HL60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109101608 ^@ http://purl.uniprot.org/uniprot/A0A8C0YT80 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Membrane http://togogenome.org/gene/7962:ifitm1 ^@ http://purl.uniprot.org/uniprot/M4HWJ6 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:ndr2 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5Y8 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109107293 ^@ http://purl.uniprot.org/uniprot/A0A8C1NR42 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/7962:LOC109045223 ^@ http://purl.uniprot.org/uniprot/A0A8C2BRL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.|||Vesicle|||secretory vesicle http://togogenome.org/gene/7962:LOC109113686 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJY0 ^@ Function|||Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM63 subfamily.|||Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover. http://togogenome.org/gene/7962:LOC109060438 ^@ http://purl.uniprot.org/uniprot/A0A8C1G3K2 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:ttyh3a ^@ http://purl.uniprot.org/uniprot/A0A8C1E2Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tweety family.|||Cell membrane|||Membrane|||Probable chloride channel. http://togogenome.org/gene/7962:dmrt3a ^@ http://purl.uniprot.org/uniprot/A0A8C1FBZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/7962:rhbg ^@ http://purl.uniprot.org/uniprot/A0A8C1Y4M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Cell membrane|||Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.|||Membrane http://togogenome.org/gene/7962:zgc:171579 ^@ http://purl.uniprot.org/uniprot/A0A8C1EQS7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109092999 ^@ http://purl.uniprot.org/uniprot/A0A8C1G4E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109085243 ^@ http://purl.uniprot.org/uniprot/A0A8C1F430 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:LOC109081253 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/7962:LOC109078875 ^@ http://purl.uniprot.org/uniprot/A0A8C1DHU2|||http://purl.uniprot.org/uniprot/A0A8C1DQM3|||http://purl.uniprot.org/uniprot/A0A8C1GDK5 ^@ Similarity ^@ Belongs to the centaurin gamma-like family. http://togogenome.org/gene/7962:LOC109063665 ^@ http://purl.uniprot.org/uniprot/A0A8C1EHI3 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/7962:entpd5a ^@ http://purl.uniprot.org/uniprot/A0A8C1HPH4 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/7962:LOC109111414 ^@ http://purl.uniprot.org/uniprot/A0A8C1E9W2 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/7962:smim15 ^@ http://purl.uniprot.org/uniprot/A0A8C1R6P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMIM15 family.|||Membrane http://togogenome.org/gene/7962:LOC109101070 ^@ http://purl.uniprot.org/uniprot/A0A8C1P9K7 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:LOC109062884 ^@ http://purl.uniprot.org/uniprot/A0A8C0XVI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109050587 ^@ http://purl.uniprot.org/uniprot/A0A8C0YS55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM263 family.|||Membrane http://togogenome.org/gene/7962:LOC109087971 ^@ http://purl.uniprot.org/uniprot/A0A8C1DY24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109046616 ^@ http://purl.uniprot.org/uniprot/Q9MXA3 ^@ Similarity ^@ Belongs to the MHC class I family. http://togogenome.org/gene/7962:tex261 ^@ http://purl.uniprot.org/uniprot/A0A8C1BZW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/7962:LOC109054933 ^@ http://purl.uniprot.org/uniprot/A0A8C1DV47 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109045698 ^@ http://purl.uniprot.org/uniprot/A0A0C6EMJ1 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109105945 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGE1 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/7962:LOC109072096 ^@ http://purl.uniprot.org/uniprot/A0A8C1M5K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. http://togogenome.org/gene/7962:shbg ^@ http://purl.uniprot.org/uniprot/A0A8C1HM03 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109110956 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNK3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109051159 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQI6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:foxi3a ^@ http://purl.uniprot.org/uniprot/A0A8C1QP48 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sult5a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C951 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109077274 ^@ http://purl.uniprot.org/uniprot/A0A8C2E2P1 ^@ Similarity ^@ Belongs to the SERF family. http://togogenome.org/gene/7962:LOC109093273 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJA4 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.|||Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. http://togogenome.org/gene/7962:LOC109079917 ^@ http://purl.uniprot.org/uniprot/A0A0C6EMJ8 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109106057 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/7962:LOC109048691 ^@ http://purl.uniprot.org/uniprot/A0A8C1H5D8|||http://purl.uniprot.org/uniprot/A0A8C1VCJ1|||http://purl.uniprot.org/uniprot/A0A8C1VD19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal targeting signal receptor family.|||Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.|||Cytoplasm|||Membrane http://togogenome.org/gene/7962:cldn10e ^@ http://purl.uniprot.org/uniprot/A0A8C1FB75|||http://purl.uniprot.org/uniprot/A0A8C1FHV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC109067529 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZVE9 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/7962:LOC109054834 ^@ http://purl.uniprot.org/uniprot/A0A8C0YIP7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/7962:hlx1 ^@ http://purl.uniprot.org/uniprot/A0A8C1QKX3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109052979 ^@ http://purl.uniprot.org/uniprot/A0A8C1XC01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HOP2 family.|||Nucleus http://togogenome.org/gene/7962:LOC109056127 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAB3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/7962:LOC109052131 ^@ http://purl.uniprot.org/uniprot/A0A8C2J3N2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109102088 ^@ http://purl.uniprot.org/uniprot/A0A8C1LHZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P4HA family.|||Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.|||Endoplasmic reticulum lumen http://togogenome.org/gene/7962:LOC109085605 ^@ http://purl.uniprot.org/uniprot/A0A8C1HM37 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109097130 ^@ http://purl.uniprot.org/uniprot/A0A8C1E618 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/7962:LOC109102244 ^@ http://purl.uniprot.org/uniprot/A0A8C2EZM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Membrane|||This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. http://togogenome.org/gene/7962:LOC109082557 ^@ http://purl.uniprot.org/uniprot/A0A8C1YJC8 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/7962:slc19a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.|||Membrane http://togogenome.org/gene/7962:LOC109054327 ^@ http://purl.uniprot.org/uniprot/A0A8C2PXV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB3 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:mc5rb ^@ http://purl.uniprot.org/uniprot/A0A8C1DQY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. http://togogenome.org/gene/7962:LOC109056907 ^@ http://purl.uniprot.org/uniprot/A0A8C1X086 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/7962:scarb2c ^@ http://purl.uniprot.org/uniprot/A0A8C1N5Q9 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/7962:drd4a ^@ http://purl.uniprot.org/uniprot/A0A8C1CBA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:eif2s1a ^@ http://purl.uniprot.org/uniprot/A0A8C1HAT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2-alpha family.|||Stress granule http://togogenome.org/gene/7962:cnfn ^@ http://purl.uniprot.org/uniprot/A0A8C1A582 ^@ Similarity ^@ Belongs to the cornifelin family. http://togogenome.org/gene/7962:LOC109095152 ^@ http://purl.uniprot.org/uniprot/A0A8C1SGD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic mitochondrial porin family.|||Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.|||Interacts with ARMC12 in a TBC1D21-dependent manner.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109104178 ^@ http://purl.uniprot.org/uniprot/A0A0C6EMJ5 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:ccl20a.3 ^@ http://purl.uniprot.org/uniprot/A0A8C1FCT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/7962:LOC109102099 ^@ http://purl.uniprot.org/uniprot/A0A8C1LIY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PGAP3 family.|||Golgi apparatus membrane|||Involved in the lipid remodeling steps of GPI-anchor maturation.|||Membrane http://togogenome.org/gene/7962:LOC109060992 ^@ http://purl.uniprot.org/uniprot/A0A8C1WSQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP72 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm http://togogenome.org/gene/7962:LOC109102292 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109073699 ^@ http://purl.uniprot.org/uniprot/A0A8C1E423 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/7962:LOC109111650 ^@ http://purl.uniprot.org/uniprot/A0A8C1DV70 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109063503 ^@ http://purl.uniprot.org/uniprot/A0A8C1F001 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:dnase1l1l ^@ http://purl.uniprot.org/uniprot/A0A8C1C1Z7 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/7962:LOC122134062 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y644 ^@ Similarity ^@ Belongs to the small GTPase superfamily. RGK family. http://togogenome.org/gene/7962:LOC109103344 ^@ http://purl.uniprot.org/uniprot/A0A8C1GFF5 ^@ Subcellular Location Annotation ^@ focal adhesion|||lamellipodium|||sarcomere http://togogenome.org/gene/7962:LOC109065263 ^@ http://purl.uniprot.org/uniprot/A0A8C2HBB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109102240 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109094148 ^@ http://purl.uniprot.org/uniprot/A0A8C1AMK9 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/7962:LOC109095600 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/7962:LOC109061927 ^@ http://purl.uniprot.org/uniprot/A0A8C1C4A3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109062002 ^@ http://purl.uniprot.org/uniprot/A0A8C1HNP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:hoxa11b ^@ http://purl.uniprot.org/uniprot/A0A8C0YFX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:cdc26 ^@ http://purl.uniprot.org/uniprot/A0A8C0YJ57 ^@ Similarity ^@ Belongs to the CDC26 family. http://togogenome.org/gene/7962:LOC109051391 ^@ http://purl.uniprot.org/uniprot/A0A8C1EDV3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109106101 ^@ http://purl.uniprot.org/uniprot/A0A8C0XW15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/7962:LOC109062665 ^@ http://purl.uniprot.org/uniprot/A0A8C1F5R5 ^@ Function|||Subcellular Location Annotation ^@ Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.|||Cytoplasm http://togogenome.org/gene/7962:LOC109050715 ^@ http://purl.uniprot.org/uniprot/A0A8C2JQU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109111876 ^@ http://purl.uniprot.org/uniprot/A0A8C2GAX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/7962:LOC109086159 ^@ http://purl.uniprot.org/uniprot/A0A8C0YRW2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/7962:LOC109107245 ^@ http://purl.uniprot.org/uniprot/A0A8C1AG28 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/7962:gpha2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YBM2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycoprotein hormones subunit alpha family.|||Heterodimer of an alpha and a beta chain.|||Secreted http://togogenome.org/gene/7962:LOC109061266 ^@ http://purl.uniprot.org/uniprot/A0A8C1AYY8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109060717 ^@ http://purl.uniprot.org/uniprot/A0A8C1MNC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 6A family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109104999 ^@ http://purl.uniprot.org/uniprot/A0A8C1IW72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/7962:LOC109056156 ^@ http://purl.uniprot.org/uniprot/D8UUE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha/beta interferon family.|||Secreted http://togogenome.org/gene/7962:LOC109087357 ^@ http://purl.uniprot.org/uniprot/A0A8C1E3F7 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109073070 ^@ http://purl.uniprot.org/uniprot/A0A8C1NJ37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:cfl1l ^@ http://purl.uniprot.org/uniprot/A0A8C1CWV5 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. http://togogenome.org/gene/7962:slc35a5 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109104194 ^@ http://purl.uniprot.org/uniprot/B1H0T9|||http://purl.uniprot.org/uniprot/P10298 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatotropin/prolactin family.|||Growth hormone plays an important role in growth control.|||Secreted http://togogenome.org/gene/7962:LOC109045691 ^@ http://purl.uniprot.org/uniprot/A0A8C1AV18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109093444 ^@ http://purl.uniprot.org/uniprot/A0A8C1SGN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/7962:LOC109086157 ^@ http://purl.uniprot.org/uniprot/A0A8C2LAX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Perikaryon|||axon|||dendrite http://togogenome.org/gene/7962:LOC109088684 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109101520 ^@ http://purl.uniprot.org/uniprot/A0A8C1T8J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/7962:LOC109064423 ^@ http://purl.uniprot.org/uniprot/A0A8C2CFS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:thoc7 ^@ http://purl.uniprot.org/uniprot/A0A8C1KCV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC7 family.|||Nucleus|||Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. http://togogenome.org/gene/7962:LOC109088765 ^@ http://purl.uniprot.org/uniprot/A0A8C1EA81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109067695 ^@ http://purl.uniprot.org/uniprot/A0A8C2I6B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Cell membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:bscl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1AEF9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109104139 ^@ http://purl.uniprot.org/uniprot/A0A8C1KVU6 ^@ Similarity ^@ Belongs to the gonadal family. http://togogenome.org/gene/7962:LOC109084002 ^@ http://purl.uniprot.org/uniprot/A0A8C2HCC4 ^@ Similarity ^@ Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family. http://togogenome.org/gene/7962:LOC109105961 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQU0 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family. http://togogenome.org/gene/7962:LOC109089035 ^@ http://purl.uniprot.org/uniprot/A0A8C1F7C9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:smdt1b ^@ http://purl.uniprot.org/uniprot/A0A8C1GYM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:c8g ^@ http://purl.uniprot.org/uniprot/A0A8C2CT60 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:ppdpfa ^@ http://purl.uniprot.org/uniprot/A0A8C1PUS9 ^@ Similarity ^@ Belongs to the PPDPF family. http://togogenome.org/gene/7962:arl11 ^@ http://purl.uniprot.org/uniprot/A0A8C1VWW8 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/7962:LOC109096817 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/7962:csnk2b ^@ http://purl.uniprot.org/uniprot/Q71U52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/7962:LOC109059695 ^@ http://purl.uniprot.org/uniprot/A0A8C1CL54 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:ano9b ^@ http://purl.uniprot.org/uniprot/A0A8C1EFC4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:foxe1 ^@ http://purl.uniprot.org/uniprot/A0A8C1UMG3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC122134049 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109112005 ^@ http://purl.uniprot.org/uniprot/A0A8C2FI45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the stanniocalcin family.|||Homodimer; disulfide-linked.|||Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales. http://togogenome.org/gene/7962:ppm1kb ^@ http://purl.uniprot.org/uniprot/A0A8C1I039 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109078912 ^@ http://purl.uniprot.org/uniprot/A0A8C1IY84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholamban family.|||Endoplasmic reticulum membrane|||Membrane|||Mitochondrion membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109091340 ^@ http://purl.uniprot.org/uniprot/A0A8C1DZB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.|||cytoskeleton http://togogenome.org/gene/7962:LOC109077562 ^@ http://purl.uniprot.org/uniprot/A0A8C2EIB5 ^@ Similarity ^@ Belongs to the MS4A family. http://togogenome.org/gene/7962:LOC109094240 ^@ http://purl.uniprot.org/uniprot/A0A8C1DUY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||phagosome membrane http://togogenome.org/gene/7962:LOC109100171 ^@ http://purl.uniprot.org/uniprot/A0A8C1L6J9 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/7962:tmed4 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109047775 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGF4 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/7962:ninj1 ^@ http://purl.uniprot.org/uniprot/A0A8C2KD03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/7962:LOC109062917 ^@ http://purl.uniprot.org/uniprot/A0A8C1FY10 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/7962:ormdl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1S1R0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORM family.|||Membrane|||Negative regulator of sphingolipid synthesis. http://togogenome.org/gene/7962:LOC109106836 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZW44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.|||centrosome http://togogenome.org/gene/7962:LOC109052754 ^@ http://purl.uniprot.org/uniprot/A0A8C1W8A8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/7962:LOC109063510 ^@ http://purl.uniprot.org/uniprot/A0A8C2BXK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GINS4/SLD5 family.|||Chromosome|||Nucleus|||Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. http://togogenome.org/gene/7962:si:ch211-223a10.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQ56 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Cytoplasmic vesicle membrane|||Golgi apparatus membrane|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109087845 ^@ http://purl.uniprot.org/uniprot/A0A8C1CUC8|||http://purl.uniprot.org/uniprot/A0A8C1HID3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Deltex family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109086739 ^@ http://purl.uniprot.org/uniprot/A0A8C1NJK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIb family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:gipc3 ^@ http://purl.uniprot.org/uniprot/A0A8C2B851 ^@ Similarity ^@ Belongs to the GIPC family. http://togogenome.org/gene/7962:LOC109085713 ^@ http://purl.uniprot.org/uniprot/A0A8C1K858 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109103969 ^@ http://purl.uniprot.org/uniprot/A0A8C1CWK8 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.|||Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. http://togogenome.org/gene/7962:LOC109084571 ^@ http://purl.uniprot.org/uniprot/A0A8C1E3E2 ^@ Function|||Similarity ^@ Belongs to the MOZART1 family.|||Required for gamma-tubulin complex recruitment to the centrosome. http://togogenome.org/gene/7962:LOC109100098 ^@ http://purl.uniprot.org/uniprot/A0A8C2F442 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/7962:LOC109092138 ^@ http://purl.uniprot.org/uniprot/A0A8C0YUG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCMBP family.|||Nucleus http://togogenome.org/gene/7962:LOC109065645 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNL2 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109095327 ^@ http://purl.uniprot.org/uniprot/A0A8C1H0Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:gng5 ^@ http://purl.uniprot.org/uniprot/A0A8C0YRY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/7962:LOC109090775 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y180 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/7962:adi1 ^@ http://purl.uniprot.org/uniprot/A0A8C2CXS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.|||Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Cell membrane|||Cytoplasm|||Monomer.|||Nucleus http://togogenome.org/gene/7962:LOC109084710 ^@ http://purl.uniprot.org/uniprot/A0A8C1E837 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:LOC109088217 ^@ http://purl.uniprot.org/uniprot/A0A8C2CNX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109046775 ^@ http://purl.uniprot.org/uniprot/A0A8C1BD34 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).|||Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/7962:LOC109110922 ^@ http://purl.uniprot.org/uniprot/A0A8C1FFW3 ^@ Subcellular Location Annotation ^@ PML body http://togogenome.org/gene/7962:zgc:158296 ^@ http://purl.uniprot.org/uniprot/A0A8C1I0P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola http://togogenome.org/gene/7962:trim45 ^@ http://purl.uniprot.org/uniprot/A0A8C1HLV7 ^@ Similarity ^@ Belongs to the TRIM/RBCC family. http://togogenome.org/gene/7962:LOC109086607 ^@ http://purl.uniprot.org/uniprot/A0A8C1VR45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109111321 ^@ http://purl.uniprot.org/uniprot/A0A8C1VGY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109057174 ^@ http://purl.uniprot.org/uniprot/A0A8C1EL41 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane http://togogenome.org/gene/7962:LOC109087261 ^@ http://purl.uniprot.org/uniprot/A0A8C1EWG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM134/TMEM230 family.|||Membrane http://togogenome.org/gene/7962:LOC109106021 ^@ http://purl.uniprot.org/uniprot/A0A8C1V960 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109071347 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZN92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane|||May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.|||Membrane http://togogenome.org/gene/7962:dcps ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HIT family.|||Cytoplasm|||Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.|||Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.|||Nucleus http://togogenome.org/gene/7962:eif4ebp1 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0U3 ^@ Similarity ^@ Belongs to the eIF4E-binding protein family. http://togogenome.org/gene/7962:LOC109059246 ^@ http://purl.uniprot.org/uniprot/Q9YH38 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).|||Belongs to the small GTPase superfamily. Ras family.|||Cell membrane|||Cytoplasm|||Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs). http://togogenome.org/gene/7962:fgf20b ^@ http://purl.uniprot.org/uniprot/A0A0C6EHQ6 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109047670 ^@ http://purl.uniprot.org/uniprot/A0A8C1B9G0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.|||Nucleus http://togogenome.org/gene/7962:LOC109062915 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVF9 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109109187 ^@ http://purl.uniprot.org/uniprot/A0A8C1HDF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:foxd7 ^@ http://purl.uniprot.org/uniprot/A0A8C1P941 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109112556 ^@ http://purl.uniprot.org/uniprot/A0A8C1D2H4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109104657 ^@ http://purl.uniprot.org/uniprot/O13136 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:si:dkey-246g23.2 ^@ http://purl.uniprot.org/uniprot/A0A8C1H3N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109048176 ^@ http://purl.uniprot.org/uniprot/A0A8C1INZ8|||http://purl.uniprot.org/uniprot/A0A8C1PNH0 ^@ Similarity ^@ Belongs to the SPIN/STSY family. http://togogenome.org/gene/7962:LOC109105600 ^@ http://purl.uniprot.org/uniprot/A0A8C1GMN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/7962:s100a1 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDV0 ^@ Similarity ^@ Belongs to the S-100 family. http://togogenome.org/gene/7962:LOC109061635 ^@ http://purl.uniprot.org/uniprot/A0A8C1CQB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.|||Membrane|||This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. http://togogenome.org/gene/7962:c7a ^@ http://purl.uniprot.org/uniprot/A0A8C1NBN7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109047273 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3C0|||http://purl.uniprot.org/uniprot/A0A8C0YCM7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109053575 ^@ http://purl.uniprot.org/uniprot/A0A8C1DKA5 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:naa80 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 56 family.|||Cell membrane|||Early endosome|||Endoplasmic reticulum|||Endosome|||Membrane|||acrosome http://togogenome.org/gene/7962:LOC109096802 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKW3|||http://purl.uniprot.org/uniprot/A0A8C1H2N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM half pint family.|||Nucleus http://togogenome.org/gene/7962:LOC109091442 ^@ http://purl.uniprot.org/uniprot/A0A8C1V344 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/7962:LOC109095933 ^@ http://purl.uniprot.org/uniprot/A0A8C1AR43 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/7962:usp12b ^@ http://purl.uniprot.org/uniprot/A0A8C1G0Z5 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/7962:LOC109113636 ^@ http://purl.uniprot.org/uniprot/A0A8C1E634 ^@ Similarity ^@ Belongs to the LAPTM4/LAPTM5 transporter family. http://togogenome.org/gene/7962:LOC109086121 ^@ http://purl.uniprot.org/uniprot/A0A8C1WUM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Golgi stack membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/7962:asphd2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YMR7 ^@ Similarity ^@ Belongs to the aspartyl/asparaginyl beta-hydroxylase family. http://togogenome.org/gene/7962:LOC109094960 ^@ http://purl.uniprot.org/uniprot/A0A8C1DUG0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109055937 ^@ http://purl.uniprot.org/uniprot/A0A8C1UPC6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109065563 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNA2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109112588 ^@ http://purl.uniprot.org/uniprot/A0A8C1DGJ0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OCIAD1 family.|||Endosome|||Interacts with STAT3.|||Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.|||The OCIA domain is necessary and sufficient for endosomal localization. http://togogenome.org/gene/7962:si:ch211-106h11.1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C022 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LRRC8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109103978 ^@ http://purl.uniprot.org/uniprot/A0A8C1UN08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109070041 ^@ http://purl.uniprot.org/uniprot/A0A8C1MUA0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109085250 ^@ http://purl.uniprot.org/uniprot/A0A8C1F1V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:naa10 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y3P0 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/7962:LOC109106884 ^@ http://purl.uniprot.org/uniprot/A0A8C1GB49 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/7962:LOC109107224 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bL35 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109059735 ^@ http://purl.uniprot.org/uniprot/A0A8C1A157 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/7962:LOC109059676 ^@ http://purl.uniprot.org/uniprot/A0A8C2Q0U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/7962:ppp1r3b ^@ http://purl.uniprot.org/uniprot/A0A8C1BWG0 ^@ Subunit ^@ Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity. http://togogenome.org/gene/7962:LOC109089341 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2Q2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:tada3l ^@ http://purl.uniprot.org/uniprot/A0A8C1HHW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NGG1 family.|||Nucleus http://togogenome.org/gene/7962:LOC109046539 ^@ http://purl.uniprot.org/uniprot/A0A8C1LK75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/7962:atp5pf ^@ http://purl.uniprot.org/uniprot/A0A8C2AH17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ATPase subunit F6 family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109064811 ^@ http://purl.uniprot.org/uniprot/A0A220NYV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:smad9 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109070622 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/7962:LOC109092152 ^@ http://purl.uniprot.org/uniprot/A0A8C1MGZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:LOC109083793 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPT4 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/7962:LOC109052358 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXF1 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109090820 ^@ http://purl.uniprot.org/uniprot/A0A8C2H8P9 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/7962:LOC109076280 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109055590 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMX6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109076297 ^@ http://purl.uniprot.org/uniprot/A0A8C1B921 ^@ Similarity ^@ Belongs to the GASK family. http://togogenome.org/gene/7962:lipf ^@ http://purl.uniprot.org/uniprot/A0A8C1CIA9 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/7962:LOC109050708 ^@ http://purl.uniprot.org/uniprot/A0A8C1MBH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109104079 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS26 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109109047 ^@ http://purl.uniprot.org/uniprot/A0A8C1NFS3 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/7962:nkx1.2la ^@ http://purl.uniprot.org/uniprot/A0A8C1E7P6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109065614 ^@ http://purl.uniprot.org/uniprot/A0A8C1SE91 ^@ Function|||Similarity ^@ Belongs to the WD repeat DCAF10 family.|||May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. http://togogenome.org/gene/7962:LOC109047172 ^@ http://purl.uniprot.org/uniprot/A0A8C1H100 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/7962:LOC109065434 ^@ http://purl.uniprot.org/uniprot/A0A8C1HUH6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:dnaaf6 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZN0 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/7962:LOC109096997 ^@ http://purl.uniprot.org/uniprot/A0A8C1XCQ4 ^@ Subcellular Location Annotation ^@ Nucleus|||cytosol http://togogenome.org/gene/7962:LOC109064096 ^@ http://purl.uniprot.org/uniprot/A0A8C1EY18 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:slc8a1b ^@ http://purl.uniprot.org/uniprot/A0A8C1ANF1|||http://purl.uniprot.org/uniprot/A0A8C1H3C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC122134063 ^@ http://purl.uniprot.org/uniprot/A0A8C1EDZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MUSTANG family.|||Nucleus http://togogenome.org/gene/7962:LOC109094150 ^@ http://purl.uniprot.org/uniprot/A0A8C1DUU0|||http://purl.uniprot.org/uniprot/A0A8C1HQV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the myelin proteolipid protein family.|||Membrane http://togogenome.org/gene/7962:LOC109048219 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVN6 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:LOC122133992 ^@ http://purl.uniprot.org/uniprot/A0A8C2AM61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/7962:slc39a1 ^@ http://purl.uniprot.org/uniprot/A0A8C2GXI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109058500 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDJ0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109050714 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M16 family.|||Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion matrix|||Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. http://togogenome.org/gene/7962:tmem208 ^@ http://purl.uniprot.org/uniprot/A0A8C1KBA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.|||Membrane http://togogenome.org/gene/7962:LOC109092149 ^@ http://purl.uniprot.org/uniprot/A0A8C1XMP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/7962:epdl1 ^@ http://purl.uniprot.org/uniprot/A0A8C1C368 ^@ Similarity ^@ Belongs to the ependymin family. http://togogenome.org/gene/7962:LOC109058833 ^@ http://purl.uniprot.org/uniprot/A0A8C1MQU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/7962:cops7a ^@ http://purl.uniprot.org/uniprot/A0A8C1IBB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109045077 ^@ http://purl.uniprot.org/uniprot/A0A8C0YDP3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:ralba ^@ http://purl.uniprot.org/uniprot/A0A8C2AM37 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. http://togogenome.org/gene/7962:LOC109081704 ^@ http://purl.uniprot.org/uniprot/A0A8C1EIC0 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/7962:acta1b ^@ http://purl.uniprot.org/uniprot/A0A8C1B1T2|||http://purl.uniprot.org/uniprot/Q7T2J3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:LOC109087358 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5R5 ^@ Similarity ^@ Belongs to the TMEM178 family. http://togogenome.org/gene/7962:LOC109100576 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZ31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:med29 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 29 family.|||Nucleus http://togogenome.org/gene/7962:LOC109045122 ^@ http://purl.uniprot.org/uniprot/A0A8C2ASJ6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL38 family. http://togogenome.org/gene/7962:LOC109050595 ^@ http://purl.uniprot.org/uniprot/A0A8C1AEQ9 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/7962:LOC109061962 ^@ http://purl.uniprot.org/uniprot/A0A8C1R8K3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/7962:LOC109106005 ^@ http://purl.uniprot.org/uniprot/A0A8C1JTT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endosulfine family.|||Cytoplasm|||Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. http://togogenome.org/gene/7962:LOC109049244 ^@ http://purl.uniprot.org/uniprot/A0A8C1EH01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actinoporin family. Sea anemone subfamily.|||Cell membrane|||Membrane|||Nematocyst|||Target cell membrane http://togogenome.org/gene/7962:LOC109089050 ^@ http://purl.uniprot.org/uniprot/A0A8C1FPI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/7962:LOC109067205 ^@ http://purl.uniprot.org/uniprot/A0A8C1I4B3 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/7962:LOC109065590 ^@ http://purl.uniprot.org/uniprot/A0A8C1RTS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/7962:LOC109086926 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTG8 ^@ Similarity ^@ Belongs to the UPF0545 family. http://togogenome.org/gene/7962:LOC109049631 ^@ http://purl.uniprot.org/uniprot/A0A8C1C3K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109062521 ^@ http://purl.uniprot.org/uniprot/A0A8C1CA97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the extended synaptotagmin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109082596 ^@ http://purl.uniprot.org/uniprot/A0A8C1EHT9 ^@ Similarity ^@ Belongs to the CENP-X/MHF2 family. http://togogenome.org/gene/7962:si:dkey-6i22.5 ^@ http://purl.uniprot.org/uniprot/A0A8C1GM35 ^@ Subcellular Location Annotation ^@ Nucleus|||kinetochore http://togogenome.org/gene/7962:LOC109081799 ^@ http://purl.uniprot.org/uniprot/A0A8C1HW77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion http://togogenome.org/gene/7962:LOC109062702 ^@ http://purl.uniprot.org/uniprot/A0A8C2INW9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:rpl34 ^@ http://purl.uniprot.org/uniprot/A0A8C1NYR5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/7962:LOC109058409 ^@ http://purl.uniprot.org/uniprot/A0A8C1EGE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM256 family.|||Membrane http://togogenome.org/gene/7962:LOC109083431 ^@ http://purl.uniprot.org/uniprot/A0A8C1F485 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109109931 ^@ http://purl.uniprot.org/uniprot/A0A8C1BW71 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109066217 ^@ http://purl.uniprot.org/uniprot/A0A8C1CMH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane|||Nucleus inner membrane http://togogenome.org/gene/7962:LOC109102951 ^@ http://purl.uniprot.org/uniprot/A0A8C1T883 ^@ Function|||Similarity ^@ Belongs to the arrestin family.|||May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins. http://togogenome.org/gene/7962:LOC109066788 ^@ http://purl.uniprot.org/uniprot/A0A8C1L9W0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/7962:LOC109090574 ^@ http://purl.uniprot.org/uniprot/A0A8C2KAV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:smad3b ^@ http://purl.uniprot.org/uniprot/A0A8C1BDV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:rps11 ^@ http://purl.uniprot.org/uniprot/O73666 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/7962:LOC109073572 ^@ http://purl.uniprot.org/uniprot/A0A8C1N515 ^@ Subcellular Location Annotation ^@ Mitochondrion intermembrane space http://togogenome.org/gene/7962:cln5 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFM0 ^@ Similarity ^@ Belongs to the CLN5 family. http://togogenome.org/gene/7962:LOC109109202 ^@ http://purl.uniprot.org/uniprot/A0A8C1CAD1|||http://purl.uniprot.org/uniprot/A0A8C1HDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/7962:LOC109095278 ^@ http://purl.uniprot.org/uniprot/A0A8C1AZJ0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109058520 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKC1 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/7962:LOC109108792 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the battenin family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109105995 ^@ http://purl.uniprot.org/uniprot/A0A8C1X0A4 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/7962:LOC109069586 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109100228 ^@ http://purl.uniprot.org/uniprot/A0A8C0YI86 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/7962:LOC109085138 ^@ http://purl.uniprot.org/uniprot/A0A8C1CXC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bL35 family.|||Mitochondrion http://togogenome.org/gene/7962:mis12 ^@ http://purl.uniprot.org/uniprot/A0A8C1HJX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mis12 family.|||kinetochore http://togogenome.org/gene/7962:tmem242 ^@ http://purl.uniprot.org/uniprot/A0A8C1PHF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/7962:LOC109066447 ^@ http://purl.uniprot.org/uniprot/A0A8C1B7P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:fam136a ^@ http://purl.uniprot.org/uniprot/A0A8C0YLA0 ^@ Similarity ^@ Belongs to the FAM136 family. http://togogenome.org/gene/7962:il17c ^@ http://purl.uniprot.org/uniprot/A0A8C2Q2N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-17 family.|||Secreted http://togogenome.org/gene/7962:LOC109095982 ^@ http://purl.uniprot.org/uniprot/A0A8C0XYK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/7962:rpl32 ^@ http://purl.uniprot.org/uniprot/A0A8C1B4Y6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/7962:stk32a ^@ http://purl.uniprot.org/uniprot/A0A8C1AJ59 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/7962:LOC109063778 ^@ http://purl.uniprot.org/uniprot/A0A8C1QIS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AVIT (prokineticin) family.|||Secreted http://togogenome.org/gene/7962:LOC109070341 ^@ http://purl.uniprot.org/uniprot/A0A8C1EMD7 ^@ Similarity ^@ Belongs to the interleukin-1 receptor family. http://togogenome.org/gene/7962:LOC109091342 ^@ http://purl.uniprot.org/uniprot/A0A8C1DVN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SWD2 family.|||Nucleus http://togogenome.org/gene/7962:LOC109109057 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions and the hemichannels.|||gap junction http://togogenome.org/gene/7962:LOC109066554 ^@ http://purl.uniprot.org/uniprot/A0A8C1F9T0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:soul4 ^@ http://purl.uniprot.org/uniprot/A0A8C1MJA9|||http://purl.uniprot.org/uniprot/A0A8C1MJB3 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/7962:LOC109104701 ^@ http://purl.uniprot.org/uniprot/A0A8C1VNM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/7962:LOC109085012 ^@ http://purl.uniprot.org/uniprot/A0A8C1CW21|||http://purl.uniprot.org/uniprot/A0A8C1CWZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109050589 ^@ http://purl.uniprot.org/uniprot/A0A8C1A5I6 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/7962:LOC109086929 ^@ http://purl.uniprot.org/uniprot/A0A8C1HTI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109092443 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7K9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:LOC109061629 ^@ http://purl.uniprot.org/uniprot/A0A8C1CR05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the opioid neuropeptide precursor family.|||Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.|||Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.|||Leumorphin has a typical opiod activity and may have anti-apoptotic effect.|||Secreted http://togogenome.org/gene/7962:tmsb ^@ http://purl.uniprot.org/uniprot/A0A8C2I7R4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.|||cytoskeleton http://togogenome.org/gene/7962:LOC109076839 ^@ http://purl.uniprot.org/uniprot/A0A8C0YD39|||http://purl.uniprot.org/uniprot/A0A8C1A367 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:LOC109057213 ^@ http://purl.uniprot.org/uniprot/A0A8C1ASN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109056218 ^@ http://purl.uniprot.org/uniprot/A0A8C1ETU2 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/7962:LOC109061190 ^@ http://purl.uniprot.org/uniprot/A0A8C2PWI5 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/7962:arpin ^@ http://purl.uniprot.org/uniprot/A0A8C2B101 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Arpin family.|||lamellipodium http://togogenome.org/gene/7962:LOC109098669 ^@ http://purl.uniprot.org/uniprot/A0A8C1VUV8|||http://purl.uniprot.org/uniprot/A0A8C2DPA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/7962:LOC109063664 ^@ http://purl.uniprot.org/uniprot/A0A8C1EKB7 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/7962:lsr ^@ http://purl.uniprot.org/uniprot/A0A8C2BCF1|||http://purl.uniprot.org/uniprot/A0A8C2FVJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the immunoglobulin superfamily. LISCH7 family.|||Membrane|||tight junction http://togogenome.org/gene/7962:LOC109082905 ^@ http://purl.uniprot.org/uniprot/A0A8C1D4Z8 ^@ Caution|||Similarity ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109099637 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tumor necrosis factor family.|||Membrane http://togogenome.org/gene/7962:LOC109053175 ^@ http://purl.uniprot.org/uniprot/A0A8C1C665 ^@ Subcellular Location Annotation ^@ PML body|||autophagosome|||cytosol http://togogenome.org/gene/7962:LOC109091639 ^@ http://purl.uniprot.org/uniprot/C6KH74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts specifically as a negative regulator of skeletal muscle growth.|||Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Secreted http://togogenome.org/gene/7962:kcnj3b ^@ http://purl.uniprot.org/uniprot/A0A8C1R5U1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.|||Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.|||Membrane|||This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. http://togogenome.org/gene/7962:klhl36 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2B5 ^@ Function ^@ Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/7962:LOC109108840 ^@ http://purl.uniprot.org/uniprot/A0A8C2JQV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/7962:LOC109057648 ^@ http://purl.uniprot.org/uniprot/A0A8C2IM46 ^@ Function ^@ Does not bind lactose, and may not bind carbohydrates. http://togogenome.org/gene/7962:LOC109111734 ^@ http://purl.uniprot.org/uniprot/A0A8C1EN34 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109111595 ^@ http://purl.uniprot.org/uniprot/A0A8C1CYP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAIF1 family.|||Induces apoptosis.|||Nucleus http://togogenome.org/gene/7962:LOC109098031 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y338 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/7962:tbxa2r ^@ http://purl.uniprot.org/uniprot/A0A8C1R6I6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:elavl2 ^@ http://purl.uniprot.org/uniprot/A0A8C1AJD3 ^@ Similarity ^@ Belongs to the RRM elav family. http://togogenome.org/gene/7962:LOC109080884 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109046630 ^@ http://purl.uniprot.org/uniprot/A0A8C1A7E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL54 family.|||Mitochondrion http://togogenome.org/gene/7962:bri3 ^@ http://purl.uniprot.org/uniprot/A0A8C1HPJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/7962:LOC109099658 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:msx2a ^@ http://purl.uniprot.org/uniprot/A0A8C2C4I4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109048896 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNF7 ^@ Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family. http://togogenome.org/gene/7962:LOC109095526 ^@ http://purl.uniprot.org/uniprot/A0A8C1K9U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR5 family.|||Lysosome http://togogenome.org/gene/7962:syndig1l ^@ http://purl.uniprot.org/uniprot/A0A8C1JN26 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109060399 ^@ http://purl.uniprot.org/uniprot/A0A8C1FET0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/7962:cldn7b ^@ http://purl.uniprot.org/uniprot/A0A8C1Z8V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:zgc:110540 ^@ http://purl.uniprot.org/uniprot/A0A8C1FI09 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/7962:LOC109095247 ^@ http://purl.uniprot.org/uniprot/A0A8C1A1R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/7962:LOC109061963 ^@ http://purl.uniprot.org/uniprot/A0A8C1DJ18 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/7962:pax5 ^@ http://purl.uniprot.org/uniprot/A0A8C1AXK9|||http://purl.uniprot.org/uniprot/A0A8C1AXL9|||http://purl.uniprot.org/uniprot/A0A8C1P3Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109066279 ^@ http://purl.uniprot.org/uniprot/A0A8C1NFW6 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/7962:LOC109097777 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACY2 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/7962:LOC109096818 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2Z2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109063914 ^@ http://purl.uniprot.org/uniprot/A0A8C1I0A9|||http://purl.uniprot.org/uniprot/A0A8C1TSX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. PAR subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109073525 ^@ http://purl.uniprot.org/uniprot/A0A8C1C1D5 ^@ Function|||Similarity ^@ Belongs to the calcitonin family.|||Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. http://togogenome.org/gene/7962:LOC109073349 ^@ http://purl.uniprot.org/uniprot/A0A8C1HWP8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:asah1b ^@ http://purl.uniprot.org/uniprot/A0A8C1DRP3 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/7962:LOC109071875 ^@ http://purl.uniprot.org/uniprot/A0A8C1S8M3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCR10/QCR9 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109076179 ^@ http://purl.uniprot.org/uniprot/Q8QFP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109104669 ^@ http://purl.uniprot.org/uniprot/A0A8C2B7L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:psen1 ^@ http://purl.uniprot.org/uniprot/A0A8C1HAY0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/7962:zgc:112271 ^@ http://purl.uniprot.org/uniprot/A0A8C2DIC1 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/7962:LOC109077531 ^@ http://purl.uniprot.org/uniprot/A0A8C1I567 ^@ Similarity ^@ Belongs to the CAMK2N family. http://togogenome.org/gene/7962:LOC109089483 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:cdc42 ^@ http://purl.uniprot.org/uniprot/A0A8C1CHN7|||http://purl.uniprot.org/uniprot/A0A8C1LDA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.|||Cell membrane|||Membrane|||Midbody|||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. http://togogenome.org/gene/7962:LOC109059803 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109110988 ^@ http://purl.uniprot.org/uniprot/A0A8C1IR90 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MAK10 family.|||Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.|||Cytoplasm http://togogenome.org/gene/7962:LOC109061408 ^@ http://purl.uniprot.org/uniprot/A0A8C1NWA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109097984 ^@ http://purl.uniprot.org/uniprot/A0A8C1CFC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/7962:LOC109094125 ^@ http://purl.uniprot.org/uniprot/A0A8C1WFZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.|||Binds with high affinity to CRF receptors 2-alpha and 2-beta.|||Secreted|||Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. http://togogenome.org/gene/7962:LOC109053751 ^@ http://purl.uniprot.org/uniprot/A0A8C1AWX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109057599 ^@ http://purl.uniprot.org/uniprot/A0A8C1BNB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.|||Mitochondrion http://togogenome.org/gene/7962:si:dkey-121b10.7 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y2C3 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/7962:LOC109081886 ^@ http://purl.uniprot.org/uniprot/A0A8C1F6K1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109093903 ^@ http://purl.uniprot.org/uniprot/A0A8C1AUM9 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/7962:LOC109088052 ^@ http://purl.uniprot.org/uniprot/A0A8C1LSU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.|||Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.|||Binds to type I and type II collagen.|||extracellular matrix http://togogenome.org/gene/7962:LOC109069439 ^@ http://purl.uniprot.org/uniprot/A0A8C1E0L4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/7962:LOC109045411 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKU5|||http://purl.uniprot.org/uniprot/A0A8C1A5K5|||http://purl.uniprot.org/uniprot/A0A8C1IPX4|||http://purl.uniprot.org/uniprot/A0A8C1IQH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:actc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZU00 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:zgc:101810 ^@ http://purl.uniprot.org/uniprot/A0A8C1MYD2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/7962:kcnk1b ^@ http://purl.uniprot.org/uniprot/A0A8C1XMN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Cell membrane|||Cytoplasmic vesicle|||Endosome|||Membrane|||Perikaryon|||Recycling endosome|||Synaptic cell membrane|||Vesicle|||dendrite http://togogenome.org/gene/7962:LOC109048158 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted|||Somatostatin inhibits the release of somatotropin. http://togogenome.org/gene/7962:LOC109099518 ^@ http://purl.uniprot.org/uniprot/A0A8C1DPY4 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109061916 ^@ http://purl.uniprot.org/uniprot/A0A8C1PEX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109110099 ^@ http://purl.uniprot.org/uniprot/A0A8C1RTS2 ^@ Similarity ^@ Belongs to the TMEM14 family. http://togogenome.org/gene/7962:LOC109055742 ^@ http://purl.uniprot.org/uniprot/A0A8C1NAC0 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/7962:LOC109081048 ^@ http://purl.uniprot.org/uniprot/A0A8C1EVN5 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/7962:LOC109049715 ^@ http://purl.uniprot.org/uniprot/A0A8C2JVQ7 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109076126 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZBS1 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/7962:LOC109056053 ^@ http://purl.uniprot.org/uniprot/A0A8C2HWS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109107893 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4U1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:cds1 ^@ http://purl.uniprot.org/uniprot/A0A8C0XXT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Membrane http://togogenome.org/gene/7962:LOC109089362 ^@ http://purl.uniprot.org/uniprot/A0A8C1B2U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:LOC109063314 ^@ http://purl.uniprot.org/uniprot/A0A8C1FQI8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109067624 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQA8 ^@ Similarity ^@ Belongs to the ANKRD34 family. http://togogenome.org/gene/7962:LOC109103918 ^@ http://purl.uniprot.org/uniprot/A0A8C1TU97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.|||Membrane|||Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons. http://togogenome.org/gene/7962:LOC109096103 ^@ http://purl.uniprot.org/uniprot/A0A8C1MCR6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/7962:trappc2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YBT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/7962:LOC109047919 ^@ http://purl.uniprot.org/uniprot/A0A8C1SIA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/7962:cryabb ^@ http://purl.uniprot.org/uniprot/A0A8C1EEK6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109099406 ^@ http://purl.uniprot.org/uniprot/A0A8C1BRA1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Interacts with PPIF; the interaction is impaired by CsA.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109077266 ^@ http://purl.uniprot.org/uniprot/A0A8C1EA41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/7962:tlcd3bb ^@ http://purl.uniprot.org/uniprot/A0A8C1DIA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109080731 ^@ http://purl.uniprot.org/uniprot/A0A8C1RQL2 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/7962:LOC109097336 ^@ http://purl.uniprot.org/uniprot/A0A8C1VGW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/7962:LOC109057503 ^@ http://purl.uniprot.org/uniprot/A0A8C1CEX3 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB5 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/7962:fgf10b ^@ http://purl.uniprot.org/uniprot/A0A8C2HB42 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/7962:LOC109109587 ^@ http://purl.uniprot.org/uniprot/A0A8C1JE66 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C19 family. USP14/UBP6 subfamily.|||Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS. http://togogenome.org/gene/7962:tmem59l ^@ http://purl.uniprot.org/uniprot/A0A8C1AY68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109061845 ^@ http://purl.uniprot.org/uniprot/A0A8C1FZ13 ^@ Function|||Similarity ^@ Belongs to the DDAH family.|||Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. http://togogenome.org/gene/7962:LOC109097868 ^@ http://purl.uniprot.org/uniprot/A0A8C1HC91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDNFR family.|||Cell membrane|||Membrane|||Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. http://togogenome.org/gene/7962:LOC109055793 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBF8|||http://purl.uniprot.org/uniprot/A0A8C2PPN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Engrailed homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109075561 ^@ http://purl.uniprot.org/uniprot/A0A8C1ERE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS29 family.|||Mitochondrion http://togogenome.org/gene/7962:dram1 ^@ http://purl.uniprot.org/uniprot/A0A8C1KNH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109065705 ^@ http://purl.uniprot.org/uniprot/A0A8C1PTW1 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/7962:LOC109103159 ^@ http://purl.uniprot.org/uniprot/A0A8C1L372 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109048948 ^@ http://purl.uniprot.org/uniprot/A0A8C1HK55 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/7962:LOC109047183 ^@ http://purl.uniprot.org/uniprot/A0A8C1ANE7 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/7962:emx1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ET11 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109055347 ^@ http://purl.uniprot.org/uniprot/A0A8C1H2H3 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:LOC109067071 ^@ http://purl.uniprot.org/uniprot/A0A8C1BX08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREC family.|||Endoplasmic reticulum membrane|||Golgi apparatus|||Melanosome|||Membrane|||Sarcoplasmic reticulum lumen|||Secreted http://togogenome.org/gene/7962:LOC109060900 ^@ http://purl.uniprot.org/uniprot/A0A8C1XGX8 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/7962:LOC109111791 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQA3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:pigc ^@ http://purl.uniprot.org/uniprot/A0A8C1CPH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGC family.|||Membrane http://togogenome.org/gene/7962:wt1a ^@ http://purl.uniprot.org/uniprot/A0A8C1HLY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EGR C2H2-type zinc-finger protein family.|||Cytoplasm|||Nucleus speckle http://togogenome.org/gene/7962:slc39a4 ^@ http://purl.uniprot.org/uniprot/A0A089ZWW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Membrane http://togogenome.org/gene/7962:LOC109047282 ^@ http://purl.uniprot.org/uniprot/A0A8C1ACI7|||http://purl.uniprot.org/uniprot/A0A8C1H0H6 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/7962:LOC109067459 ^@ http://purl.uniprot.org/uniprot/A0A8C1FRA6 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/7962:LOC109103256 ^@ http://purl.uniprot.org/uniprot/A0A8C1SP80|||http://purl.uniprot.org/uniprot/A0A8C2K7K1 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:b3gnt7 ^@ http://purl.uniprot.org/uniprot/A0A8C1HDS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/7962:LOC109110351 ^@ http://purl.uniprot.org/uniprot/A0A8C1WRQ2 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/7962:unk ^@ http://purl.uniprot.org/uniprot/A0A8C1CTA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unkempt family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109070495 ^@ http://purl.uniprot.org/uniprot/A0A8C1ISG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the riboflavin transporter family.|||Cell membrane|||Membrane|||Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. http://togogenome.org/gene/7962:LOC109100789 ^@ http://purl.uniprot.org/uniprot/A0A8C1AS94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109089164 ^@ http://purl.uniprot.org/uniprot/A0A8C1AQB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTA family.|||Membrane http://togogenome.org/gene/7962:trarg1a ^@ http://purl.uniprot.org/uniprot/A0A8C2K971 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:vegfab ^@ http://purl.uniprot.org/uniprot/A0A8C2CTX4 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/7962:LOC109067021 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8A3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/7962:LOC109066838 ^@ http://purl.uniprot.org/uniprot/A0A8C1BDI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NRF1/Ewg family.|||Nucleus http://togogenome.org/gene/7962:LOC109088585 ^@ http://purl.uniprot.org/uniprot/A0A8C1F928 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-delta family.|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/7962:slc25a51a ^@ http://purl.uniprot.org/uniprot/A0A8C1DAY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/7962:LOC109071129 ^@ http://purl.uniprot.org/uniprot/A0A8C1BAR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C12 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:acot13 ^@ http://purl.uniprot.org/uniprot/A0A8C1FEG6 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/7962:LOC109046009 ^@ http://purl.uniprot.org/uniprot/A0A8C1H217 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7962:armt1 ^@ http://purl.uniprot.org/uniprot/A0A8C0YGL6 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/7962:LOC109052443 ^@ http://purl.uniprot.org/uniprot/A0A8C2FM91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109052643 ^@ http://purl.uniprot.org/uniprot/A0A8C1DPJ4 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. http://togogenome.org/gene/7962:LOC109096064 ^@ http://purl.uniprot.org/uniprot/A0A8C1S4Y3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. http://togogenome.org/gene/7962:LOC109103922 ^@ http://purl.uniprot.org/uniprot/A0A8C1F8G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/7962:exosc1 ^@ http://purl.uniprot.org/uniprot/A0A8C1ZM04 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/7962:LOC109052568 ^@ http://purl.uniprot.org/uniprot/A0A8C1UT42 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109106825 ^@ http://purl.uniprot.org/uniprot/A0A8C1BB85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/7962:LOC109056062 ^@ http://purl.uniprot.org/uniprot/A0A8C1ESJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:hs6st2 ^@ http://purl.uniprot.org/uniprot/A0A8C1MMM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.|||Belongs to the sulfotransferase 6 family.|||Membrane http://togogenome.org/gene/7962:LOC109052525 ^@ http://purl.uniprot.org/uniprot/A0A8C0YA54 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109055996 ^@ http://purl.uniprot.org/uniprot/A0A8C1LS10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SAM50/omp85 family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:zgc:110353 ^@ http://purl.uniprot.org/uniprot/A0A8C1Q2B0 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:LOC109048536 ^@ http://purl.uniprot.org/uniprot/A0A8C1HXQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109091869 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGG1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109087764 ^@ http://purl.uniprot.org/uniprot/A0A8C1HNI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109085116 ^@ http://purl.uniprot.org/uniprot/A0A8C1SNH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/7962:LOC109089915 ^@ http://purl.uniprot.org/uniprot/A0A8C0YLP6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/7962:LOC109097888 ^@ http://purl.uniprot.org/uniprot/A0A8C1ARQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:si:dkey-243k1.3 ^@ http://purl.uniprot.org/uniprot/A0A8C1V646 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/7962:LOC109097138 ^@ http://purl.uniprot.org/uniprot/A0A8C2I080 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/7962:LOC109094035 ^@ http://purl.uniprot.org/uniprot/A0A8C1TV61 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109048021 ^@ http://purl.uniprot.org/uniprot/A0A8C1JBJ4 ^@ Function|||Similarity ^@ Belongs to the SKP1 family.|||Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. http://togogenome.org/gene/7962:LOC109048941 ^@ http://purl.uniprot.org/uniprot/Q5S1U4|||http://purl.uniprot.org/uniprot/Q9I9I0 ^@ Domain|||Function|||Similarity ^@ Belongs to the metallothionein superfamily. Type 1 family.|||Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.|||Metallothioneins have a high content of cysteine residues that bind various heavy metals. http://togogenome.org/gene/7962:LOC109083909 ^@ http://purl.uniprot.org/uniprot/A0A8C1NYU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:srp9 ^@ http://purl.uniprot.org/uniprot/A0A8C2HV03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP9 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm http://togogenome.org/gene/7962:LOC109065153 ^@ http://purl.uniprot.org/uniprot/A0A8C1FLR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||Membrane raft|||caveola http://togogenome.org/gene/7962:foxq2 ^@ http://purl.uniprot.org/uniprot/A0A8C1AYF5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109095369 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y0G4 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/7962:atg4a ^@ http://purl.uniprot.org/uniprot/A0A8C1NH93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/7962:med7 ^@ http://purl.uniprot.org/uniprot/A0A8C1GZW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/7962:LOC109085100 ^@ http://purl.uniprot.org/uniprot/A0A8C1D2X3 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/7962:LOC109111828 ^@ http://purl.uniprot.org/uniprot/A0A8C1CUB4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. http://togogenome.org/gene/7962:LOC109102611 ^@ http://purl.uniprot.org/uniprot/A0A8C1P6T3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:LOC109064698 ^@ http://purl.uniprot.org/uniprot/Q3V5Y3 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/7962:LOC109105053 ^@ http://purl.uniprot.org/uniprot/A0A8C1B577 ^@ Similarity ^@ Belongs to the GSK-3-binding protein family. http://togogenome.org/gene/7962:LOC109083155 ^@ http://purl.uniprot.org/uniprot/A0A8C2JL57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TARBP2 family.|||Cytoplasm|||Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.|||Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. http://togogenome.org/gene/7962:LOC109107045 ^@ http://purl.uniprot.org/uniprot/A0A8C1CXM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OST4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109053989 ^@ http://purl.uniprot.org/uniprot/A0A8C1D330 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/7962:rpl36a ^@ http://purl.uniprot.org/uniprot/A0A8C1IAV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109073041 ^@ http://purl.uniprot.org/uniprot/A0A8C1L9T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109050612 ^@ http://purl.uniprot.org/uniprot/A0A8C1ALG5 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/7962:LOC109068405 ^@ http://purl.uniprot.org/uniprot/A0A8C1DCW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 63 family.|||Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.|||Endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109070135 ^@ http://purl.uniprot.org/uniprot/A0A8C1EES2 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109048639 ^@ http://purl.uniprot.org/uniprot/A0A8C2GXN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/7962:dpf3 ^@ http://purl.uniprot.org/uniprot/A0A8C1F9W0|||http://purl.uniprot.org/uniprot/A0A8C1FD02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the requiem/DPF family.|||Nucleus http://togogenome.org/gene/7962:LOC109049790 ^@ http://purl.uniprot.org/uniprot/A0A8C1AIC2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/7962:LOC109092193 ^@ http://purl.uniprot.org/uniprot/A0A8C1B0Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ST7 family.|||Membrane http://togogenome.org/gene/7962:LOC109105566 ^@ http://purl.uniprot.org/uniprot/A0A8C1DW09 ^@ Similarity ^@ Belongs to the GORASP family. http://togogenome.org/gene/7962:hmga1a ^@ http://purl.uniprot.org/uniprot/A0A8C1LSI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGA family.|||Nucleus http://togogenome.org/gene/7962:LOC109054387 ^@ http://purl.uniprot.org/uniprot/A0A8C0XW77 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/7962:mt2 ^@ http://purl.uniprot.org/uniprot/O13269|||http://purl.uniprot.org/uniprot/Q5S1U3 ^@ Domain|||Function|||Similarity ^@ Belongs to the metallothionein superfamily. Type 1 family.|||Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.|||Metallothioneins have a high content of cysteine residues that bind various heavy metals. http://togogenome.org/gene/7962:LOC109066840 ^@ http://purl.uniprot.org/uniprot/A0A8C1N129 ^@ Similarity ^@ Belongs to the UPF0538 family. http://togogenome.org/gene/7962:LOC109094154 ^@ http://purl.uniprot.org/uniprot/A0A8C1JMK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic13 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:cmc2 ^@ http://purl.uniprot.org/uniprot/A0A8C1PC81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109091658 ^@ http://purl.uniprot.org/uniprot/A0A8C1FW65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGR2 family.|||Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.|||Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109050645 ^@ http://purl.uniprot.org/uniprot/A0A8C1BSZ3|||http://purl.uniprot.org/uniprot/A0A8C1BWM1|||http://purl.uniprot.org/uniprot/A0A8C2IWD2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/7962:LOC109079008 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Secreted http://togogenome.org/gene/7962:LOC109102594 ^@ http://purl.uniprot.org/uniprot/A0A8C1J630 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/7962:LOC109062376 ^@ http://purl.uniprot.org/uniprot/A0A8C2HFW9 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. LCMT family.|||Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. http://togogenome.org/gene/7962:LOC109099474 ^@ http://purl.uniprot.org/uniprot/A0A8C1J7T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORM family.|||Endoplasmic reticulum membrane|||Membrane|||Negative regulator of sphingolipid synthesis. http://togogenome.org/gene/7962:LOC109081842 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/7962:timm23a ^@ http://purl.uniprot.org/uniprot/A0A8C1X8W2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109065284 ^@ http://purl.uniprot.org/uniprot/A0A8C2KJU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYYR1 family.|||Membrane http://togogenome.org/gene/7962:ppm1da ^@ http://purl.uniprot.org/uniprot/A0A8C1R024 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/7962:LOC109110969 ^@ http://purl.uniprot.org/uniprot/A0A8C1L8X7 ^@ Similarity|||Subunit ^@ Belongs to the TRAPPC13 family.|||Part of the multisubunit TRAPP (transport protein particle) complex. http://togogenome.org/gene/7962:LOC109078114 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC50/LEM3 family.|||Cell membrane|||Golgi apparatus|||Membrane|||secretory vesicle membrane http://togogenome.org/gene/7962:polr2h ^@ http://purl.uniprot.org/uniprot/A0A8C2KBR2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/7962:LOC109109157 ^@ http://purl.uniprot.org/uniprot/A0A8C1H079 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parvin family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109080404 ^@ http://purl.uniprot.org/uniprot/A0A8C1EBC6 ^@ Similarity ^@ Belongs to the ZC3H15/TMA46 family. http://togogenome.org/gene/7962:kxd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1GJI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KXD1 family.|||Lysosome membrane http://togogenome.org/gene/7962:LOC109077056 ^@ http://purl.uniprot.org/uniprot/A0A8C1CBR1 ^@ Similarity ^@ Belongs to the peptidase M50A family. http://togogenome.org/gene/7962:LOC109111814 ^@ http://purl.uniprot.org/uniprot/A0A8C1BWQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109061487 ^@ http://purl.uniprot.org/uniprot/A0A8C1F6H1 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/7962:LOC109061874 ^@ http://purl.uniprot.org/uniprot/A0A8C1CIW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:cmtm6 ^@ http://purl.uniprot.org/uniprot/A0A8C1BYZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109080839 ^@ http://purl.uniprot.org/uniprot/A0A8C2I3G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.|||Belongs to the TBCC family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109053425 ^@ http://purl.uniprot.org/uniprot/A0A8C1B713|||http://purl.uniprot.org/uniprot/A0A8C1NKC8 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/7962:lin7c ^@ http://purl.uniprot.org/uniprot/A0A8C1HAU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/7962:LOC109087783 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6T4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:LOC109063343 ^@ http://purl.uniprot.org/uniprot/A0A8C1BQK5 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/7962:LOC109067327 ^@ http://purl.uniprot.org/uniprot/A0A8C2GRY0 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/7962:LOC109052609 ^@ http://purl.uniprot.org/uniprot/A0A8C0XZI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORG/CEP family.|||Endomembrane system http://togogenome.org/gene/7962:LOC109112573 ^@ http://purl.uniprot.org/uniprot/A0A8C1D507|||http://purl.uniprot.org/uniprot/A0A8C1D5Y2|||http://purl.uniprot.org/uniprot/A0A8C1HKI8 ^@ Similarity ^@ Belongs to the SLAIN motif-containing family. http://togogenome.org/gene/7962:LOC109050032 ^@ http://purl.uniprot.org/uniprot/A0A8C1DD88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109054125 ^@ http://purl.uniprot.org/uniprot/A0A8C1TF94 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/7962:f2r ^@ http://purl.uniprot.org/uniprot/A0A8C1BUB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109088396 ^@ http://purl.uniprot.org/uniprot/A0A8C1B0V0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109076146 ^@ http://purl.uniprot.org/uniprot/A0A8C1CQP0|||http://purl.uniprot.org/uniprot/A0A8C1HHK1 ^@ Function|||Similarity ^@ Belongs to the SOS response-associated peptidase family.|||Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction. http://togogenome.org/gene/7962:LOC109049246 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVM0 ^@ Similarity ^@ Belongs to the SNAPIN family. http://togogenome.org/gene/7962:LOC109093160 ^@ http://purl.uniprot.org/uniprot/A0A8C0XUC4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26 family.|||Heterodimer of 2 subunits, IMMPL1 and IMMPL2.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:ccnj ^@ http://purl.uniprot.org/uniprot/A0A8C1C7N1 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109064246 ^@ http://purl.uniprot.org/uniprot/A0A8C1D4W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109092926 ^@ http://purl.uniprot.org/uniprot/A0A8C1BPC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/7962:LOC109059030 ^@ http://purl.uniprot.org/uniprot/A0A8C2FA75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CCDC124 family.|||Interacts with RASGEF1B.|||Required for proper progression of late cytokinetic stages. http://togogenome.org/gene/7962:LOC109100240 ^@ http://purl.uniprot.org/uniprot/A0A8C2ATQ2 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/7962:tnfsf18 ^@ http://purl.uniprot.org/uniprot/A0A8C1C039 ^@ Similarity ^@ Belongs to the tumor necrosis factor family. http://togogenome.org/gene/7962:dbx1a ^@ http://purl.uniprot.org/uniprot/A0A8C0XZR6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:gstt2 ^@ http://purl.uniprot.org/uniprot/A0A0M3VGN6 ^@ Similarity ^@ Belongs to the GST superfamily. Theta family. http://togogenome.org/gene/7962:LOC109056198 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5H5 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/7962:tmem97 ^@ http://purl.uniprot.org/uniprot/A0A8C1UGU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM97/sigma-2 receptor family.|||Endoplasmic reticulum membrane|||Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.|||Membrane|||Nucleus membrane|||Rough endoplasmic reticulum membrane http://togogenome.org/gene/7962:LOC109112843 ^@ http://purl.uniprot.org/uniprot/A0A8C2KJJ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC3 family.|||Component of the ER membrane protein complex (EMC).|||Membrane http://togogenome.org/gene/7962:arl3l2 ^@ http://purl.uniprot.org/uniprot/A0A8C0YSZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/7962:nop16 ^@ http://purl.uniprot.org/uniprot/A0A8C1UXF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP16 family.|||nucleolus http://togogenome.org/gene/7962:lamtor3 ^@ http://purl.uniprot.org/uniprot/A0A8C1XM68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR3 family.|||Endosome membrane|||Late endosome membrane http://togogenome.org/gene/7962:LOC109066060 ^@ http://purl.uniprot.org/uniprot/A0A8C2A584 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/7962:wdyhv1 ^@ http://purl.uniprot.org/uniprot/A0A8C1AKW6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NTAQ1 family.|||Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.|||Monomer. http://togogenome.org/gene/7962:prkab1a ^@ http://purl.uniprot.org/uniprot/A0A8C1BMD4 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/7962:LOC109049865 ^@ http://purl.uniprot.org/uniprot/A0A8C1LM01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/7962:banf1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EF12 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109094174 ^@ http://purl.uniprot.org/uniprot/A0A8C1KIW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat TRM82 family.|||Forms a heterodimer with the catalytic subunit METTL1.|||Nucleus|||Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. http://togogenome.org/gene/7962:LOC109079238 ^@ http://purl.uniprot.org/uniprot/A0A8C1HX38 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:tlcd4a ^@ http://purl.uniprot.org/uniprot/A0A8C1TMN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109097964 ^@ http://purl.uniprot.org/uniprot/A0A8C0XUL4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:gpr35b ^@ http://purl.uniprot.org/uniprot/A0A8C2EN97 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:LOC109068427 ^@ http://purl.uniprot.org/uniprot/A0A8C1T0J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SIX/Sine oculis homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109100107 ^@ http://purl.uniprot.org/uniprot/A0A8C1PLV3 ^@ Domain|||Function|||Subunit ^@ Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.|||Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.|||The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase. http://togogenome.org/gene/7962:LOC109049123 ^@ http://purl.uniprot.org/uniprot/A0A8C1H0M9 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/7962:LOC109070842 ^@ http://purl.uniprot.org/uniprot/A0A8C1D3H8 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/7962:LOC109112743 ^@ http://purl.uniprot.org/uniprot/A0A8C1E7K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Chromosome|||Nucleus|||Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. http://togogenome.org/gene/7962:eif3c ^@ http://purl.uniprot.org/uniprot/A0A8C1H646 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Cytoplasm http://togogenome.org/gene/7962:LOC109080248 ^@ http://purl.uniprot.org/uniprot/A0A8C1XMJ4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/7962:LOC109068273 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJF8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109074213 ^@ http://purl.uniprot.org/uniprot/A0A8C1MII4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/7962:LOC109047177 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y9B8 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/7962:LOC109103830 ^@ http://purl.uniprot.org/uniprot/A0A8C1N6E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:hoxc6b ^@ http://purl.uniprot.org/uniprot/A0A8C1RXZ6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:sh2b3 ^@ http://purl.uniprot.org/uniprot/A0A8C1BH81 ^@ Similarity ^@ Belongs to the SH2B adapter family. http://togogenome.org/gene/7962:LOC109062346 ^@ http://purl.uniprot.org/uniprot/A0A8C1E9N7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109062008 ^@ http://purl.uniprot.org/uniprot/A0A8C1HNQ5 ^@ Caution|||Similarity ^@ Belongs to the peptidase M10A family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109065230 ^@ http://purl.uniprot.org/uniprot/A0A8C1H8E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/7962:LOC109095578 ^@ http://purl.uniprot.org/uniprot/A0A8C1IZ78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complement C6/C7/C8/C9 family.|||Secreted http://togogenome.org/gene/7962:LOC109066007 ^@ http://purl.uniprot.org/uniprot/A0A8C1E140 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/7962:LOC109063106 ^@ http://purl.uniprot.org/uniprot/A0A8C1HS65 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/7962:st7l ^@ http://purl.uniprot.org/uniprot/A0A8C1AZW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ST7 family.|||Membrane http://togogenome.org/gene/7962:LOC109058477 ^@ http://purl.uniprot.org/uniprot/A0A8C1W8P3 ^@ Function|||Similarity ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. http://togogenome.org/gene/7962:neurod4 ^@ http://purl.uniprot.org/uniprot/A0A8C1Y186 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109075441 ^@ http://purl.uniprot.org/uniprot/A0A8C1F576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109084529 ^@ http://purl.uniprot.org/uniprot/A0A8C1DQP0 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/7962:uchl3 ^@ http://purl.uniprot.org/uniprot/A0A8C2CD75 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/7962:LOC109066324 ^@ http://purl.uniprot.org/uniprot/A0A8C1SFW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglutaminase-like superfamily. PNGase family.|||Cytoplasm|||Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins. http://togogenome.org/gene/7962:LOC109096720 ^@ http://purl.uniprot.org/uniprot/A0A8C1VTL1 ^@ Similarity ^@ Belongs to the PDCD4 family. http://togogenome.org/gene/7962:LOC109093919 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVA9 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/7962:lamp1a ^@ http://purl.uniprot.org/uniprot/A0A8C1H8Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/7962:LOC109097019 ^@ http://purl.uniprot.org/uniprot/A0A2U9IYA4 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/7962:metap2b ^@ http://purl.uniprot.org/uniprot/A0A8C1NGT1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.|||Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm|||Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis. http://togogenome.org/gene/7962:thap1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EYL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the THAP1 family.|||DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.|||nucleoplasm http://togogenome.org/gene/7962:LOC109106144 ^@ http://purl.uniprot.org/uniprot/A0A8C2C6S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the R-spondin family.|||Secreted http://togogenome.org/gene/7962:trmt112 ^@ http://purl.uniprot.org/uniprot/A0A8C1CTM7 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/7962:oafa ^@ http://purl.uniprot.org/uniprot/A0A8C1TC05 ^@ Similarity ^@ Belongs to the OAF family. http://togogenome.org/gene/7962:casp3a ^@ http://purl.uniprot.org/uniprot/T1WD39 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/7962:LOC109095102 ^@ http://purl.uniprot.org/uniprot/A0A8C1AGW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/7962:LOC109053710 ^@ http://purl.uniprot.org/uniprot/A0A8C0YQG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIP3 family.|||Membrane http://togogenome.org/gene/7962:myorg ^@ http://purl.uniprot.org/uniprot/A0A8C1B135 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/7962:timp2b ^@ http://purl.uniprot.org/uniprot/A0A8C1A6P8 ^@ Similarity ^@ Belongs to the protease inhibitor I35 (TIMP) family. http://togogenome.org/gene/7962:LOC109091723 ^@ http://purl.uniprot.org/uniprot/A0A8C1VX42 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/7962:LOC109059579 ^@ http://purl.uniprot.org/uniprot/A0A8C1XWI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109079780 ^@ http://purl.uniprot.org/uniprot/A0A8C1FD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/7962:KEF38_p01 ^@ http://purl.uniprot.org/uniprot/P24951|||http://purl.uniprot.org/uniprot/Q6V9F6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme b groups non-covalently.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.|||Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.|||Membrane|||Mitochondrion inner membrane|||The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.|||The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools. http://togogenome.org/gene/7962:LOC109087332 ^@ http://purl.uniprot.org/uniprot/A0A8C1PWK3 ^@ Similarity ^@ Belongs to the SMIM7 family. http://togogenome.org/gene/7962:LOC109079818 ^@ http://purl.uniprot.org/uniprot/A0A8C1FHQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the claudin family.|||Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109048683 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVC0 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZP domain family. ZPC subfamily.|||Cell membrane|||Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.|||Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.|||The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.|||Zona pellucida http://togogenome.org/gene/7962:sumo1 ^@ http://purl.uniprot.org/uniprot/A0A8C1EZ49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109100577 ^@ http://purl.uniprot.org/uniprot/A0A8C1AY94 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/7962:LOC109061817 ^@ http://purl.uniprot.org/uniprot/A0A8C2PSD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/7962:LOC109098909 ^@ http://purl.uniprot.org/uniprot/A0A8C1W9V7 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/7962:LOC109049864 ^@ http://purl.uniprot.org/uniprot/A0A8C1I555 ^@ Function|||Similarity ^@ Belongs to the WD repeat ARPC1 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. http://togogenome.org/gene/7962:LOC109048098 ^@ http://purl.uniprot.org/uniprot/A0A8C1LDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/7962:LOC109099815 ^@ http://purl.uniprot.org/uniprot/A0A8C2LBU7 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/7962:LOC109069362 ^@ http://purl.uniprot.org/uniprot/A0A8C1TUL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane|||May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.|||Membrane http://togogenome.org/gene/7962:LOC109111776 ^@ http://purl.uniprot.org/uniprot/A0A8C1AY19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109075292 ^@ http://purl.uniprot.org/uniprot/A0A8C1CTD3 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/7962:LOC109093150 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0L9 ^@ Similarity ^@ Belongs to the GPATCH1 family. http://togogenome.org/gene/7962:LOC109057692 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y1D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREG family.|||Secreted http://togogenome.org/gene/7962:LOC109087356 ^@ http://purl.uniprot.org/uniprot/A0A8C1ETG3 ^@ Similarity|||Subunit ^@ Belongs to the GILT family.|||Dimer; disulfide-linked. http://togogenome.org/gene/7962:LOC109067298 ^@ http://purl.uniprot.org/uniprot/A0A8C2J6T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylin family.|||Secreted http://togogenome.org/gene/7962:LOC109065565 ^@ http://purl.uniprot.org/uniprot/A0A8C1N5R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/7962:ehd4 ^@ http://purl.uniprot.org/uniprot/A0A8C1CNF0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/7962:gprin3b ^@ http://purl.uniprot.org/uniprot/A0A8C1AFN9 ^@ Function ^@ May be involved in neurite outgrowth. http://togogenome.org/gene/7962:LOC109111920 ^@ http://purl.uniprot.org/uniprot/A0A8C1SVE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109068167 ^@ http://purl.uniprot.org/uniprot/A0A8C1KNN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109113600 ^@ http://purl.uniprot.org/uniprot/A0A8C2DQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/7962:KEF38_p03 ^@ http://purl.uniprot.org/uniprot/P24979 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/7962:prkar2aa ^@ http://purl.uniprot.org/uniprot/A0A8C1HAK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109066290 ^@ http://purl.uniprot.org/uniprot/A0A8C2GX75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:LOC109052791 ^@ http://purl.uniprot.org/uniprot/A0A8C1AI72 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/7962:LOC109052508 ^@ http://purl.uniprot.org/uniprot/A0A8C1DSC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Cell membrane|||Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.|||Membrane http://togogenome.org/gene/7962:LOC109078148 ^@ http://purl.uniprot.org/uniprot/A0A8C1FDL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the yippee family.|||Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.|||centromere http://togogenome.org/gene/7962:LOC122133952 ^@ http://purl.uniprot.org/uniprot/A0A8C2A1Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ST7 family.|||Membrane http://togogenome.org/gene/7962:LOC109055768 ^@ http://purl.uniprot.org/uniprot/A0A8C1FVM7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:clrn1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BJ35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/7962:peli1a ^@ http://purl.uniprot.org/uniprot/A0A8C1A4T1 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/7962:LOC109084552 ^@ http://purl.uniprot.org/uniprot/A0A8C1DVP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/7962:LOC109078083 ^@ http://purl.uniprot.org/uniprot/A0A8C2KR67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/7962:LOC109091864 ^@ http://purl.uniprot.org/uniprot/A0A8C1KM47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109081920 ^@ http://purl.uniprot.org/uniprot/A0A0C6E599 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/7962:LOC109110964 ^@ http://purl.uniprot.org/uniprot/A0A8C1RY65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NKAIN family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109063598 ^@ http://purl.uniprot.org/uniprot/A0A8C1HUD3 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/7962:tspan14 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z5K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/7962:txn ^@ http://purl.uniprot.org/uniprot/A0A8C2HF34 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/7962:LOC109073962 ^@ http://purl.uniprot.org/uniprot/A0A8C1FNP7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the lunapark family.|||Endoplasmic reticulum membrane|||Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.|||Plays a role in determining ER morphology.|||The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation. http://togogenome.org/gene/7962:dbndd1 ^@ http://purl.uniprot.org/uniprot/A0A8C1BD05 ^@ Similarity ^@ Belongs to the dysbindin family. http://togogenome.org/gene/7962:LOC109109108 ^@ http://purl.uniprot.org/uniprot/A0A8C0YHE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-alpha family. G(12) subfamily.|||Membrane http://togogenome.org/gene/7962:LOC109112641 ^@ http://purl.uniprot.org/uniprot/A0A8C1HQV8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:LOC109111442 ^@ http://purl.uniprot.org/uniprot/A0A8C1JV40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/7962:LOC109098409 ^@ http://purl.uniprot.org/uniprot/A0A8C1EJ35|||http://purl.uniprot.org/uniprot/A0A8C1EPV2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Golgi apparatus membrane|||Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.|||Membrane|||The cofactor is mostly bound to the substrate. http://togogenome.org/gene/7962:LOC109095990 ^@ http://purl.uniprot.org/uniprot/A0A8C1A2F1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109081708 ^@ http://purl.uniprot.org/uniprot/A0A8C1JWA1 ^@ Similarity ^@ Belongs to the Asterix family. http://togogenome.org/gene/7962:LOC109066526 ^@ http://purl.uniprot.org/uniprot/Q03422 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta-2-microglobulin family.|||Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).|||Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules (By similarity).|||Secreted http://togogenome.org/gene/7962:LOC109048728 ^@ http://purl.uniprot.org/uniprot/A0A8C1MM44 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109085173 ^@ http://purl.uniprot.org/uniprot/A0A8C1XIE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/7962:LOC109052695 ^@ http://purl.uniprot.org/uniprot/A0A8C1E829 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109105102 ^@ http://purl.uniprot.org/uniprot/A0A8C1G1J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). http://togogenome.org/gene/7962:LOC109112779 ^@ http://purl.uniprot.org/uniprot/A0A8C2JV39 ^@ Similarity|||Subunit ^@ Belongs to the 14-3-3 family.|||Homodimer, and heterodimer with other family members. http://togogenome.org/gene/7962:LOC109050017 ^@ http://purl.uniprot.org/uniprot/A0A8C1CRM8 ^@ Function|||Similarity ^@ Belongs to the SPSB family.|||May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/7962:LOC109058783 ^@ http://purl.uniprot.org/uniprot/A0A8C1BBG1 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/7962:LOC109095906 ^@ http://purl.uniprot.org/uniprot/A0A8C1KV21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ashwin family.|||Nucleus http://togogenome.org/gene/7962:LOC109079279 ^@ http://purl.uniprot.org/uniprot/A0A8C1FKR4 ^@ Similarity ^@ Belongs to the BIVM family. http://togogenome.org/gene/7962:mapre3a ^@ http://purl.uniprot.org/uniprot/A0A8C1CM96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPRE family.|||cytoskeleton http://togogenome.org/gene/7962:LOC109094108 ^@ http://purl.uniprot.org/uniprot/A0A8C1DV25 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109074891 ^@ http://purl.uniprot.org/uniprot/A0A8C1CCL3 ^@ Similarity ^@ Belongs to the IER family. http://togogenome.org/gene/7962:LOC109081485 ^@ http://purl.uniprot.org/uniprot/A0A8C1V1X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola|||sarcolemma http://togogenome.org/gene/7962:LOC109058412 ^@ http://purl.uniprot.org/uniprot/A0A8C1EG29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/7962:LOC109082237 ^@ http://purl.uniprot.org/uniprot/A0A8C1I392 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:LOC109078689 ^@ http://purl.uniprot.org/uniprot/A0A8C1M9T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/7962:LOC109056651 ^@ http://purl.uniprot.org/uniprot/A0A8C2BJG5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/7962:irx1b ^@ http://purl.uniprot.org/uniprot/A0A8C1AZS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/7962:LOC109046470 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP40 family.|||Cytoplasm http://togogenome.org/gene/7962:LOC109048710 ^@ http://purl.uniprot.org/uniprot/A0A8C1HI59 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109070664 ^@ http://purl.uniprot.org/uniprot/A0A8C1U0T0 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/7962:LOC109046048 ^@ http://purl.uniprot.org/uniprot/A0A8C1BG61 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/7962:igf2a ^@ http://purl.uniprot.org/uniprot/A0A8C1HXF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/7962:sst1.1 ^@ http://purl.uniprot.org/uniprot/A0A0A7X868 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted|||Somatostatin inhibits the release of somatotropin. http://togogenome.org/gene/7962:LOC109050449 ^@ http://purl.uniprot.org/uniprot/A0A8C1NP72 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109111457 ^@ http://purl.uniprot.org/uniprot/A0A8C0YNQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/7962:LOC109066435 ^@ http://purl.uniprot.org/uniprot/A0A8C1IUS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/7962:LOC109087706 ^@ http://purl.uniprot.org/uniprot/A0A8C1FH25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/7962:LOC109099482 ^@ http://purl.uniprot.org/uniprot/A0A8C1BH27 ^@ Similarity ^@ Belongs to the peptidase M67C family. http://togogenome.org/gene/7962:LOC109100547 ^@ http://purl.uniprot.org/uniprot/A0A8C2CG02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/7962:LOC109076982 ^@ http://purl.uniprot.org/uniprot/A0A8C1HY62 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/7962:LOC109063036 ^@ http://purl.uniprot.org/uniprot/A0A8C2C0M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/7962:LOC109099613 ^@ http://purl.uniprot.org/uniprot/A0A8C1CRT8 ^@ Similarity ^@ Belongs to the PRR15 family. http://togogenome.org/gene/7962:LOC109096666 ^@ http://purl.uniprot.org/uniprot/A0A8C1AFH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/7962:magoh ^@ http://purl.uniprot.org/uniprot/A0A8C2A2C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/7962:LOC109071043 ^@ http://purl.uniprot.org/uniprot/A0A8C1NNT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/7962:LOC109102552 ^@ http://purl.uniprot.org/uniprot/A0A8C0Y5G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. CNC subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/7962:lcat ^@ http://purl.uniprot.org/uniprot/A0A8C2K216 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/7962:LOC109106925 ^@ http://purl.uniprot.org/uniprot/A0A8C1QYV1 ^@ Subcellular Location Annotation ^@ Nucleus|||perinuclear region http://togogenome.org/gene/7962:LOC109048739 ^@ http://purl.uniprot.org/uniprot/A0A8C1K886 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/7962:LOC109074737 ^@ http://purl.uniprot.org/uniprot/A0A8C2I2F5 ^@ Similarity ^@ Belongs to the sprouty family. http://togogenome.org/gene/7962:LOC109062354 ^@ http://purl.uniprot.org/uniprot/A0A8C1D7F1|||http://purl.uniprot.org/uniprot/A0A8C1DAI1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/7962:LOC109050790 ^@ http://purl.uniprot.org/uniprot/A0A8C1A0D3 ^@ Similarity ^@ Belongs to the vasopressin/oxytocin family. http://togogenome.org/gene/7962:LOC109051082 ^@ http://purl.uniprot.org/uniprot/A0A8C2FT01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM98 family.|||Endoplasmic reticulum membrane|||Membrane|||extracellular exosome http://togogenome.org/gene/7962:rab39ba ^@ http://purl.uniprot.org/uniprot/A0A8C1TJX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/7962:LOC109092192 ^@ http://purl.uniprot.org/uniprot/A0A8C1AVW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/7962:LOC109107083 ^@ http://purl.uniprot.org/uniprot/A0A8C1XM74 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/7962:LOC109059152 ^@ http://purl.uniprot.org/uniprot/A0A8C2A8L0 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/7962:LOC109096915 ^@ http://purl.uniprot.org/uniprot/A0A8C1IRR0 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/7962:gnb1a ^@ http://purl.uniprot.org/uniprot/A5LG10 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/7962:smad6b ^@ http://purl.uniprot.org/uniprot/A0A8C1BDY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/7962:LOC109053149 ^@ http://purl.uniprot.org/uniprot/A0A8C2KL91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom22 family.|||Mitochondrion outer membrane http://togogenome.org/gene/7962:LOC109049169 ^@ http://purl.uniprot.org/uniprot/A0A8C1FWL6 ^@ Subcellular Location Annotation ^@ Cleavage furrow|||Endosome membrane|||Membrane|||Midbody|||Recycling endosome membrane http://togogenome.org/gene/7962:LOC109075791 ^@ http://purl.uniprot.org/uniprot/A0A8C2ANP7 ^@ Similarity ^@ Belongs to the ependymin family. http://togogenome.org/gene/7962:LOC109083291 ^@ http://purl.uniprot.org/uniprot/A0A8C1DFG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/7962:sirt2 ^@ http://purl.uniprot.org/uniprot/A0A8C1LWS0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the sirtuin family. Class I subfamily.|||Binds 1 zinc ion per subunit.|||NAD-dependent protein deacetylase. http://togogenome.org/gene/7962:LOC109084018 ^@ http://purl.uniprot.org/uniprot/A0A8C1DWA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/7962:LOC109104783 ^@ http://purl.uniprot.org/uniprot/A0A8C0YK62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.|||Membrane http://togogenome.org/gene/7962:LOC109050691 ^@ http://purl.uniprot.org/uniprot/A0A8C1I0C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the BMT2 family.|||Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.|||S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/7962:LOC109048750 ^@ http://purl.uniprot.org/uniprot/A0A8C1S5I8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/7962:LOC109098497 ^@ http://purl.uniprot.org/uniprot/A0A8C2DNN3 ^@ Similarity ^@ Belongs to the proteasome subunit S10 family. http://togogenome.org/gene/7962:LOC109061252 ^@ http://purl.uniprot.org/uniprot/A0A8C1H5B7 ^@ Function ^@ Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. http://togogenome.org/gene/7962:mpdu1b ^@ http://purl.uniprot.org/uniprot/A0A8C2EZK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPDU1 (TC 2.A.43.3) family.|||Membrane http://togogenome.org/gene/7962:LOC109054595 ^@ http://purl.uniprot.org/uniprot/A0A8C2BIP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/7962:LOC109112841 ^@ http://purl.uniprot.org/uniprot/A0A8C1GBE7 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/7962:zgc:194209 ^@ http://purl.uniprot.org/uniprot/A0A8C0YHN1 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/7962:LOC109059495 ^@ http://purl.uniprot.org/uniprot/A0A8C1UE25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/7962:LOC109062589 ^@ http://purl.uniprot.org/uniprot/A0A8C1LS04 ^@ Similarity ^@ Belongs to the LSM12 family. http://togogenome.org/gene/7962:LOC109109104 ^@ http://purl.uniprot.org/uniprot/A0A8C1A4A2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/7962:fam163ab ^@ http://purl.uniprot.org/uniprot/A0A8C1HVA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/7962:tmpob ^@ http://purl.uniprot.org/uniprot/A0A8C1BN03 ^@ Similarity ^@ Belongs to the LEM family. http://togogenome.org/gene/7962:LOC109105526 ^@ http://purl.uniprot.org/uniprot/A0A8C1CTR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/7962:LOC109101409 ^@ http://purl.uniprot.org/uniprot/A0A8C1R4U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/7962:atp5mea ^@ http://purl.uniprot.org/uniprot/A0A8C1B7I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase e subunit family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/7962:LOC109051882 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z332 ^@ Similarity ^@ Belongs to the TAPR1 family. http://togogenome.org/gene/7962:LOC109061149 ^@ http://purl.uniprot.org/uniprot/A0A8C1CLX6 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/7962:LOC109069315 ^@ http://purl.uniprot.org/uniprot/A0A8C1C602 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/7962:cbr1 ^@ http://purl.uniprot.org/uniprot/A0A8C1B8Z2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/7962:extl2 ^@ http://purl.uniprot.org/uniprot/A0A8C0XVU4 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/7962:hoxa13b ^@ http://purl.uniprot.org/uniprot/A0A8C1X3F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/7962:cplx4b ^@ http://purl.uniprot.org/uniprot/A0A8C1EF43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/7962:LOC109050738 ^@ http://purl.uniprot.org/uniprot/A0A8C1PAC6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||gap junction http://togogenome.org/gene/7962:LOC109047822 ^@ http://purl.uniprot.org/uniprot/A0A8C1Z7N2 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/7962:LOC109098382 ^@ http://purl.uniprot.org/uniprot/A0A8C1E5V9 ^@ Function|||Similarity ^@ Belongs to the vestigial family.|||May act as a specific coactivator for the mammalian TEFs. http://togogenome.org/gene/7962:LOC109087036 ^@ http://purl.uniprot.org/uniprot/A0A8C1PWE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NALF family.|||Membrane http://togogenome.org/gene/7962:LOC109063602 ^@ http://purl.uniprot.org/uniprot/A0A8C1EA00 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/7962:LOC109060403 ^@ http://purl.uniprot.org/uniprot/A0A8C1JQ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WSCD family.|||Membrane http://togogenome.org/gene/7962:LOC109096025 ^@ http://purl.uniprot.org/uniprot/A0A8C1BKZ8 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/7962:odad4 ^@ http://purl.uniprot.org/uniprot/A0A8C0YKV8 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/7962:LOC109047215 ^@ http://purl.uniprot.org/uniprot/A0A8C1ADP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/7962:LOC109107203 ^@ http://purl.uniprot.org/uniprot/A0A8C1RXI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/7962:LOC109091574 ^@ http://purl.uniprot.org/uniprot/A0A8C1HDS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM171 family.|||Membrane http://togogenome.org/gene/7962:LOC109067939 ^@ http://purl.uniprot.org/uniprot/A0A8C1D6V7 ^@ Similarity ^@ Belongs to the SNF7 family.