http://togogenome.org/gene/888061:AXF15_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A109W5V8 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/888061:AXF15_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQY5 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/888061:AXF15_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN95 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/888061:AXF15_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPQ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/888061:AXF15_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A120KMX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.|||Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin. http://togogenome.org/gene/888061:AXF15_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12805 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/888061:AXF15_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A109W5B1 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/888061:AXF15_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP95 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11180 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRN5 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/888061:AXF15_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSM2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/888061:AXF15_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSD1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQB0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN42 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/888061:AXF15_RS12970 ^@ http://purl.uniprot.org/uniprot/A0A109WC29 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/888061:AXF15_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A109W6R2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A109W6H4 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/888061:AXF15_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/888061:AXF15_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRJ9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQK9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/888061:AXF15_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ38 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/888061:AXF15_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ83 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/888061:AXF15_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A120KN52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/888061:AXF15_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A109W6A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/888061:AXF15_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A120KMU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/888061:AXF15_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/888061:AXF15_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A0X8JND3 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/888061:AXF15_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11120 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRJ3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/888061:AXF15_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A109W5H4 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/888061:AXF15_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A120KNN0 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/888061:AXF15_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A109W5D5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/888061:AXF15_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A109WBQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12140 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRV8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/888061:AXF15_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/888061:AXF15_RS07200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQY3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/888061:AXF15_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A109W695 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A109W5J7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbiQ family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A109W640 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/888061:AXF15_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/888061:AXF15_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A109W6P9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/888061:AXF15_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/888061:AXF15_RS12505 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/888061:AXF15_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/888061:AXF15_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/888061:AXF15_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS10 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/888061:AXF15_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPD8 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/888061:AXF15_RS12565 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS06 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/888061:AXF15_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A109W5R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSJ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/888061:AXF15_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQZ0 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/888061:AXF15_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A120KN22 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/888061:AXF15_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN92 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/888061:AXF15_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A120KMN9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/888061:AXF15_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/888061:AXF15_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPN3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/888061:AXF15_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A109W5V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.|||Cell membrane|||Mediates zinc uptake. May also transport other divalent cations.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSC9 ^@ Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/888061:AXF15_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A109W6M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/888061:AXF15_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A109W5S4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/888061:AXF15_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A120KMZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ48 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/888061:AXF15_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNI9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/888061:AXF15_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A109W619 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/888061:AXF15_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ77 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/888061:AXF15_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSE5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/888061:AXF15_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A109W5Y2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW6 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/888061:AXF15_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR29 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS12050 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQW8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/888061:AXF15_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/888061:AXF15_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQG7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/888061:AXF15_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A120KN08 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSB6 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/888061:AXF15_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A120KN86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPI9 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/888061:AXF15_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPN0 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/888061:AXF15_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPU3 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/888061:AXF15_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A109W6I3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/888061:AXF15_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQS1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/888061:AXF15_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS05700 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPS3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/888061:AXF15_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ95 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/888061:AXF15_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPG9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQG6 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/888061:AXF15_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/888061:AXF15_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A109W5R8 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/888061:AXF15_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A109W6D7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/888061:AXF15_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMX1 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/888061:AXF15_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/888061:AXF15_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY6 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/888061:AXF15_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/888061:AXF15_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A109W5M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A109W6I1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS62 ^@ Similarity ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. http://togogenome.org/gene/888061:AXF15_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/888061:AXF15_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSH6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/888061:AXF15_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A109W5N7 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/888061:AXF15_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A109W5R1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/888061:AXF15_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A120KN38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/888061:AXF15_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A109W6C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/888061:AXF15_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/888061:AXF15_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPW3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/888061:AXF15_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A109W6A3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/888061:AXF15_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR96 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/888061:AXF15_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/888061:AXF15_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A120KNF6 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/888061:AXF15_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A109W6Q7 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/888061:AXF15_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A120KMR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/888061:AXF15_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ80 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/888061:AXF15_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ81 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQW5 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/888061:AXF15_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A109W5E8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/888061:AXF15_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A120KN91 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS60 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/888061:AXF15_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQE1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Membrane http://togogenome.org/gene/888061:AXF15_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A109W5E9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/888061:AXF15_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/888061:AXF15_RS07300 ^@ http://purl.uniprot.org/uniprot/A0A109WBD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A120KNR1 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/888061:AXF15_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A109W6E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS11885 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP05 ^@ Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. http://togogenome.org/gene/888061:AXF15_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRK8 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. http://togogenome.org/gene/888061:AXF15_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A109W5C2 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A109W676 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A109W6B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26C family.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A109W5F2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/888061:AXF15_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A109W5I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A120KMX1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/888061:AXF15_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A109W684 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/888061:AXF15_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A109W6R4 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/888061:AXF15_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ08 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/888061:AXF15_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPW2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A120KNU1 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/888061:AXF15_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A109W5Y6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/888061:AXF15_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPY6 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/888061:AXF15_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSR4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A109W6Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A109W608 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/888061:AXF15_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A109W621 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQN6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSF9 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/888061:AXF15_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A109W5K1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/888061:AXF15_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A109WBA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/888061:AXF15_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A120KNC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/888061:AXF15_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/888061:AXF15_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/888061:AXF15_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/888061:AXF15_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A109W5L5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/888061:AXF15_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPC2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/888061:AXF15_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ78 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/888061:AXF15_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A109W5D7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/888061:AXF15_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A109WBX1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/888061:AXF15_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11630 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRU5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/888061:AXF15_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPG8 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/888061:AXF15_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/888061:AXF15_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPF1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/888061:AXF15_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/888061:AXF15_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A109W5E5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/888061:AXF15_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/888061:AXF15_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPX0 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/888061:AXF15_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A120KMP0 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/888061:AXF15_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A109W5W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN21 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/888061:AXF15_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS32 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/888061:AXF15_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A109W635 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/888061:AXF15_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A120KN05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS99 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/888061:AXF15_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A120KP23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/888061:AXF15_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/888061:AXF15_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A109W5C5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/888061:AXF15_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A120KNF3 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/888061:AXF15_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/888061:AXF15_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNM8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/888061:AXF15_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/888061:AXF15_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A109W5S8 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/888061:AXF15_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQD2 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/888061:AXF15_RS10100 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/888061:AXF15_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPV3 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/888061:AXF15_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS54 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS09390 ^@ http://purl.uniprot.org/uniprot/A0A120KN78 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPJ8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A109W5D2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/888061:AXF15_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A109W5Y4 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/888061:AXF15_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQK5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/888061:AXF15_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A120KNC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/888061:AXF15_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A109W6M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/888061:AXF15_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/888061:AXF15_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A109W5T8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/888061:AXF15_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRB0 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/888061:AXF15_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB4 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/888061:AXF15_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A120KN61 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/888061:AXF15_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP42 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR93 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/888061:AXF15_RS12420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSI4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSB0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQH3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/888061:AXF15_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A109W5N6 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. http://togogenome.org/gene/888061:AXF15_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A109W5G1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/888061:AXF15_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A109W670 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A109WBM0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/888061:AXF15_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/888061:AXF15_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPX1 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/888061:AXF15_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A109W5X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A109W6H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A109W5C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/888061:AXF15_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A120KND8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/888061:AXF15_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A120KMV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A109W6B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQC1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A109W5G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/888061:AXF15_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/888061:AXF15_RS08805 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRU2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/888061:AXF15_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A109W6K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/888061:AXF15_RS04530 ^@ http://purl.uniprot.org/uniprot/A0A109W5R3 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/888061:AXF15_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNV2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/888061:AXF15_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/888061:AXF15_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNH7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/888061:AXF15_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQW7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/888061:AXF15_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN23 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A120KMY0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/888061:AXF15_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/888061:AXF15_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS07045 ^@ http://purl.uniprot.org/uniprot/A0A120KN27 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/888061:AXF15_RS12255 ^@ http://purl.uniprot.org/uniprot/A0A109W6J5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/888061:AXF15_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS02 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPC8 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A109W5R2 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/888061:AXF15_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A120KMZ1 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/888061:AXF15_RS13090 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS89 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ33 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/888061:AXF15_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSA1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. PhnX family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/888061:AXF15_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ69 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/888061:AXF15_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/888061:AXF15_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A120KMS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/888061:AXF15_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A120KMQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A109WAN4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/888061:AXF15_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP50 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/888061:AXF15_RS13905 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/888061:AXF15_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR60 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/888061:AXF15_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/888061:AXF15_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/888061:AXF15_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A109W5L8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/888061:AXF15_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMW3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/888061:AXF15_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR62 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/888061:AXF15_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSB5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/888061:AXF15_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/888061:AXF15_RS11765 ^@ http://purl.uniprot.org/uniprot/A0A109W6I8 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/888061:AXF15_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A109W5X3 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/888061:AXF15_RS01840 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP57 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A109W628 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/888061:AXF15_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM2 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/888061:AXF15_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A109W629 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/888061:AXF15_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A120KMT0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/888061:AXF15_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSA8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/888061:AXF15_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP24 ^@ Function|||Similarity ^@ Belongs to the DtxR/MntR family.|||In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP. http://togogenome.org/gene/888061:AXF15_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPU8 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/888061:AXF15_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A109W6D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/888061:AXF15_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS13025 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRZ1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/888061:AXF15_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/888061:AXF15_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRL1 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/888061:AXF15_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A109W5C7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/888061:AXF15_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN27 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/888061:AXF15_RS12385 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB0 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/888061:AXF15_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A120KNP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/888061:AXF15_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A109W6Q0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPR6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNV0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ61 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/888061:AXF15_RS11635 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQE4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/888061:AXF15_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMU6 ^@ Similarity ^@ Belongs to the AAE transporter (TC 2.A.81) family. http://togogenome.org/gene/888061:AXF15_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP5 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/888061:AXF15_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A120KNS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A120KN03 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/888061:AXF15_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A109W6K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ10 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A109W612 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ03 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/888061:AXF15_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR25 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/888061:AXF15_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/888061:AXF15_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMZ0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/888061:AXF15_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A109W5R5 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPQ1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/888061:AXF15_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNK6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/888061:AXF15_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQN7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/888061:AXF15_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS49 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/888061:AXF15_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A0X8JT10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/888061:AXF15_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS11090 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/888061:AXF15_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMZ6 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/888061:AXF15_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A120KMZ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A109W6K0 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/888061:AXF15_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A109WBN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A109W6N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A109W5B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/888061:AXF15_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNZ7 ^@ Function|||Similarity ^@ Belongs to the peptidase M16 family.|||Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. http://togogenome.org/gene/888061:AXF15_RS12055 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A120KMN5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/888061:AXF15_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS30 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/888061:AXF15_RS12990 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A109W6F6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/888061:AXF15_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A109W5I2 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/888061:AXF15_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A120KMY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/888061:AXF15_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSE8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/888061:AXF15_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/888061:AXF15_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/888061:AXF15_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A109W5D6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/888061:AXF15_RS11075 ^@ http://purl.uniprot.org/uniprot/A0A120KNA7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homohexamer.|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/888061:AXF15_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A109W5L6 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/888061:AXF15_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPE8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/888061:AXF15_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP9 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/888061:AXF15_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR8 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/888061:AXF15_RS09235 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/888061:AXF15_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC7 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/888061:AXF15_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A120KNQ6 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNL9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/888061:AXF15_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A120KNR3 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/888061:AXF15_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/888061:AXF15_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNZ4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A120KMQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS09100 ^@ http://purl.uniprot.org/uniprot/A0A109WBK8 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/888061:AXF15_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A120KN48 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/888061:AXF15_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/888061:AXF15_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A109W5A0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPG6 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b. http://togogenome.org/gene/888061:AXF15_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/888061:AXF15_RS11970 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11900 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRS3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/888061:AXF15_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A109W611 ^@ Similarity ^@ Belongs to the NAD synthetase family. http://togogenome.org/gene/888061:AXF15_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/888061:AXF15_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A109W5W0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A120KMQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/888061:AXF15_RS09040 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQX9 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A120KN15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/888061:AXF15_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN84 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/888061:AXF15_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A109W6P4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/888061:AXF15_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSC1 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/888061:AXF15_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A109WBB7 ^@ Similarity ^@ Belongs to the iron/manganese superoxide dismutase family. http://togogenome.org/gene/888061:AXF15_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A120KN34 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/888061:AXF15_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A109W5Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/888061:AXF15_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A120KN47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/888061:AXF15_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQB5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/888061:AXF15_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQL9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/888061:AXF15_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A120KN29 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/888061:AXF15_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR24 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/888061:AXF15_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP22 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A109W654 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/888061:AXF15_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A109W6S3 ^@ Function|||Similarity ^@ Belongs to the rubredoxin family.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/888061:AXF15_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A109WBZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/888061:AXF15_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPE5 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/888061:AXF15_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS13 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/888061:AXF15_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A109W683 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/888061:AXF15_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A120KMS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/888061:AXF15_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/888061:AXF15_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A109WBV1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/888061:AXF15_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPF9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A120KNV1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS10790 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRH2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/888061:AXF15_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRH8 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/888061:AXF15_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRF2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/888061:AXF15_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A109W686 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/888061:AXF15_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR05 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/888061:AXF15_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/888061:AXF15_RS05525 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPL5 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/888061:AXF15_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A120KN99 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/888061:AXF15_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/888061:AXF15_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/888061:AXF15_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRT8 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/888061:AXF15_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPT8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/888061:AXF15_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A109W6D3 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/888061:AXF15_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A109W6G2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPT4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/888061:AXF15_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A120KMT9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/888061:AXF15_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A109WB85 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/888061:AXF15_RS11450 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/888061:AXF15_RS04285 ^@ http://purl.uniprot.org/uniprot/A0A109W5Q4 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/888061:AXF15_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A0X8JT26 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/888061:AXF15_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A109W5G1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/888061:AXF15_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRH4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/888061:AXF15_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS91 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/888061:AXF15_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ47 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A109W602 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/888061:AXF15_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A109W5S1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A120KNC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/888061:AXF15_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR82 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/888061:AXF15_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMW2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A120KN92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A120KNA8 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/888061:AXF15_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNF7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10995 ^@ http://purl.uniprot.org/uniprot/A0A109W6G0 ^@ Caution|||Function|||Similarity ^@ Belongs to the IspF family.|||Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQQ7 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A109W665 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/888061:AXF15_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A109WAV3 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/888061:AXF15_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A109W636 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/888061:AXF15_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A120KN24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/888061:AXF15_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A109W6E2 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/888061:AXF15_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A109W5L4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS11945 ^@ http://purl.uniprot.org/uniprot/A0A109WBY3 ^@ Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family. http://togogenome.org/gene/888061:AXF15_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A109W610 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/888061:AXF15_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPK0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/888061:AXF15_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRK9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNR1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/888061:AXF15_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A109W5K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRH6 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/888061:AXF15_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/888061:AXF15_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A120KN16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/888061:AXF15_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A109W5C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ05 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A109WB94 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/888061:AXF15_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A109W6L0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/888061:AXF15_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A120KN88 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/888061:AXF15_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A120KMP8 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/888061:AXF15_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSA0 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/888061:AXF15_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A109WB19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ13 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/888061:AXF15_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/888061:AXF15_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR92 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/888061:AXF15_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A120KN56 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/888061:AXF15_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS45 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/888061:AXF15_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS12590 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/888061:AXF15_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/888061:AXF15_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A109W668 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/888061:AXF15_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/888061:AXF15_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/888061:AXF15_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/888061:AXF15_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/888061:AXF15_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A109WBG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A120KNC9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/888061:AXF15_RS07195 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSE1 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/888061:AXF15_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMW5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/888061:AXF15_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP90 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/888061:AXF15_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMV7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/888061:AXF15_RS12415 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRS5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/888061:AXF15_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRR0 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/888061:AXF15_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS11150 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRD8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/888061:AXF15_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A109W6G8 ^@ Similarity ^@ Belongs to the bacterial glucokinase family. http://togogenome.org/gene/888061:AXF15_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA8 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/888061:AXF15_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A109W672 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP38 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/888061:AXF15_RS11975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A120KN72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/888061:AXF15_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A109W5I4 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/888061:AXF15_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQM7 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/888061:AXF15_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A109W5M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/888061:AXF15_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP27 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/888061:AXF15_RS12400 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPV7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/888061:AXF15_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPC9 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/888061:AXF15_RS02105 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNK8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/888061:AXF15_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSI6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A120KN14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/888061:AXF15_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/888061:AXF15_RS12775 ^@ http://purl.uniprot.org/uniprot/A0A109W6L6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRF1 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/888061:AXF15_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/888061:AXF15_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A109W5A9 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/888061:AXF15_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ0 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/888061:AXF15_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS11930 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/888061:AXF15_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/888061:AXF15_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS39 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/888061:AXF15_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A0X8JT36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRN3 ^@ Similarity ^@ Belongs to the DDAH family. http://togogenome.org/gene/888061:AXF15_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A120KMR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/888061:AXF15_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A120KMX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/888061:AXF15_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/888061:AXF15_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ94 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/888061:AXF15_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A109WC16 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMV5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/888061:AXF15_RS04395 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/888061:AXF15_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPS9 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/888061:AXF15_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNX0 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/888061:AXF15_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A120KMY6 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/888061:AXF15_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/888061:AXF15_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRL7 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/888061:AXF15_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQS8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/888061:AXF15_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ42 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/888061:AXF15_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A109WBJ8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/888061:AXF15_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP81 ^@ Function|||Similarity ^@ Belongs to the carbamoyltransferase HypF family.|||Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. http://togogenome.org/gene/888061:AXF15_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A109W5F5 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/888061:AXF15_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPL0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/888061:AXF15_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/888061:AXF15_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A120KNG4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPS8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A109WBR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/888061:AXF15_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPH4 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/888061:AXF15_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A120KMQ9 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. http://togogenome.org/gene/888061:AXF15_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A109W6N4 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/888061:AXF15_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/888061:AXF15_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQL7 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/888061:AXF15_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A109W649 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ67 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS13900 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNG3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/888061:AXF15_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A109W5Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/888061:AXF15_RS11675 ^@ http://purl.uniprot.org/uniprot/A0A120KP10 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/888061:AXF15_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSC7 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/888061:AXF15_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A120KMT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A109WAY2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS10705 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP13 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/888061:AXF15_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CheZ family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN25 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A120KMX4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/888061:AXF15_RS11110 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSK1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRG2 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/888061:AXF15_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A109W630 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A0X8JND6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/888061:AXF15_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A120KNS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/888061:AXF15_RS12010 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/888061:AXF15_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ62 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/888061:AXF15_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A109W5B7 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/888061:AXF15_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQJ7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/888061:AXF15_RS12160 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/888061:AXF15_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A109W5J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP59 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/888061:AXF15_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPV6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMW4 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/888061:AXF15_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A120KN00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPK3 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/888061:AXF15_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A109W5E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/888061:AXF15_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/888061:AXF15_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ27 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/888061:AXF15_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A0X8JT20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A120KN39 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/888061:AXF15_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||In the C-terminal section; belongs to the AccA family.|||In the N-terminal section; belongs to the AccD/PCCB family. http://togogenome.org/gene/888061:AXF15_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR26 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A120KNS0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/888061:AXF15_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/888061:AXF15_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ26 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/888061:AXF15_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A109W680 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/888061:AXF15_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR16 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/888061:AXF15_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A109W5N5 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/888061:AXF15_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A120KMY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/888061:AXF15_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPV0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A109W5J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A109WAZ3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/888061:AXF15_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM9 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/888061:AXF15_RS12090 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRX0 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A109W5H9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/888061:AXF15_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ01 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/888061:AXF15_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A109W5N8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A120KNE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/888061:AXF15_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A109W5A3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPW1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/888061:AXF15_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQF9 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/888061:AXF15_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A109W6D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/888061:AXF15_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPJ0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/888061:AXF15_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQM2 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/888061:AXF15_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A109W6A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT4 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/888061:AXF15_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A0X8JND4 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/888061:AXF15_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRF0 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/888061:AXF15_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A120KMR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/888061:AXF15_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP17 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/888061:AXF15_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A120KN17 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/888061:AXF15_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A120KN28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY9 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/888061:AXF15_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/888061:AXF15_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP44 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/888061:AXF15_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A120KN18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/888061:AXF15_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRX6 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/888061:AXF15_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/888061:AXF15_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRP4 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/888061:AXF15_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A120KN98 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/888061:AXF15_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A120KNV6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/888061:AXF15_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPR1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/888061:AXF15_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/888061:AXF15_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN02 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/888061:AXF15_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A109W5E4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/888061:AXF15_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A109W5P9 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/888061:AXF15_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A109W5H1 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/888061:AXF15_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPI1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A109W698 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/888061:AXF15_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPM4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN89 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. http://togogenome.org/gene/888061:AXF15_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A109WB03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN96 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/888061:AXF15_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A109W637 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/888061:AXF15_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A109W6A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A0X8JMY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/888061:AXF15_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A120KND5 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/888061:AXF15_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A109W6N7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNC2 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/888061:AXF15_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRQ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/888061:AXF15_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQH2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/888061:AXF15_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP62 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/888061:AXF15_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ9 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/888061:AXF15_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRB9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/888061:AXF15_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRK1 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/888061:AXF15_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/888061:AXF15_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A120KN68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A120KN19 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/888061:AXF15_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQD6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS11625 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/888061:AXF15_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRA0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/888061:AXF15_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbiQ family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/888061:AXF15_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPE3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/888061:AXF15_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ72 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/888061:AXF15_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQB2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/888061:AXF15_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A120KN36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/888061:AXF15_RS12675 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A109W6R6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/888061:AXF15_RS00860 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM3 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/888061:AXF15_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP91 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A109W6N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQT0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/888061:AXF15_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A109W692 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A109W5P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/888061:AXF15_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ79 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/888061:AXF15_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A120KMQ2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/888061:AXF15_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS95 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/888061:AXF15_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRX8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/888061:AXF15_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A109W5W7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A120KMW4 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/888061:AXF15_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR3 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/888061:AXF15_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPU6 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/888061:AXF15_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPJ2 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/888061:AXF15_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSF2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/888061:AXF15_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A120KNP9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/888061:AXF15_RS11595 ^@ http://purl.uniprot.org/uniprot/A0A120KNB7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/888061:AXF15_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/888061:AXF15_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A109W5Q8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11905 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/888061:AXF15_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNS0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/888061:AXF15_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN41 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/888061:AXF15_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP26 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/888061:AXF15_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN79 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/888061:AXF15_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ0 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/888061:AXF15_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A109W5J1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/888061:AXF15_RS11575 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRQ6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/888061:AXF15_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A109W6C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRA9 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A109W5X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OpgD/OpgG family.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/888061:AXF15_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQJ4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/888061:AXF15_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR72 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/888061:AXF15_RS12220 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSK3 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/888061:AXF15_RS09650 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR54 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ71 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/888061:AXF15_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQI4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/888061:AXF15_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A109W697 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRI1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPG4 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/888061:AXF15_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/888061:AXF15_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRT1 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/888061:AXF15_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A120KNW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/888061:AXF15_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPP8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNL4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/888061:AXF15_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP63 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/888061:AXF15_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNG0 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/888061:AXF15_RS08455 ^@ http://purl.uniprot.org/uniprot/A0A109W657 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/888061:AXF15_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQM0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/888061:AXF15_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A120KN64 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/888061:AXF15_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT1 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/888061:AXF15_RS11015 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/888061:AXF15_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/888061:AXF15_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/888061:AXF15_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRX3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/888061:AXF15_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPH2 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm3 family. http://togogenome.org/gene/888061:AXF15_RS11070 ^@ http://purl.uniprot.org/uniprot/A0A109W6C2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/888061:AXF15_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQD3 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/888061:AXF15_RS14220 ^@ http://purl.uniprot.org/uniprot/A0A120KMR8 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/888061:AXF15_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A120KN66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/888061:AXF15_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY4 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNK3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A109W6E8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/888061:AXF15_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A109WB14 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A120KNH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRJ4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS31 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/888061:AXF15_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP76 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/888061:AXF15_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/888061:AXF15_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A109W597 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/888061:AXF15_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/888061:AXF15_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/888061:AXF15_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPF8 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/888061:AXF15_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPA5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/888061:AXF15_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A109W6I6 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/888061:AXF15_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A109W5V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11685 ^@ http://purl.uniprot.org/uniprot/A0A109W6J0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/888061:AXF15_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A109W5W4 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/888061:AXF15_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A109W5G8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/888061:AXF15_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN81 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/888061:AXF15_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNM2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/888061:AXF15_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNN5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/888061:AXF15_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP45 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP77 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/888061:AXF15_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A109W675 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/888061:AXF15_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A109W645 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/888061:AXF15_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP87 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/888061:AXF15_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/888061:AXF15_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNZ5 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/888061:AXF15_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/888061:AXF15_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSE0 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/888061:AXF15_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/888061:AXF15_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A109W5U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/888061:AXF15_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS65 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/888061:AXF15_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A120KMW8 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A120KMX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/888061:AXF15_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/888061:AXF15_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRH9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11890 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRU9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/888061:AXF15_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNT5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/888061:AXF15_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A109W6J6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/888061:AXF15_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPH8 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/888061:AXF15_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A109W6B5 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/888061:AXF15_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPU7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/888061:AXF15_RS12355 ^@ http://purl.uniprot.org/uniprot/A0A109W6H1 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/888061:AXF15_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A120KMM8 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/888061:AXF15_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A120KN69 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/888061:AXF15_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A109W5P1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/888061:AXF15_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A109W5T6 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPQ9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.|||Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.|||Homodecamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/888061:AXF15_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ84 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/888061:AXF15_RS10690 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRE6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/888061:AXF15_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/888061:AXF15_RS11920 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSH0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR99 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/888061:AXF15_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS84 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/888061:AXF15_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A120KNA9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A109W5Q5 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/888061:AXF15_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/888061:AXF15_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A109W6A9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/888061:AXF15_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP75 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPE2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/888061:AXF15_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRW4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/888061:AXF15_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A109W5W5 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/888061:AXF15_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN00 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/888061:AXF15_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A120KMP1 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/888061:AXF15_RS12785 ^@ http://purl.uniprot.org/uniprot/A0A109W6M8 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/888061:AXF15_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNY8 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/888061:AXF15_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRQ8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/888061:AXF15_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPS0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/888061:AXF15_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A120KMX5 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/888061:AXF15_RS13030 ^@ http://purl.uniprot.org/uniprot/A0A120KNH6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A120KP20 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/888061:AXF15_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQU6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A109W5W1 ^@ Function ^@ Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/888061:AXF15_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A109WBJ2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRM9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/888061:AXF15_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNN3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/888061:AXF15_RS03060 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNX7 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/888061:AXF15_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS61 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/888061:AXF15_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A109W5Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/888061:AXF15_RS09975 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR01 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/888061:AXF15_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSJ2 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/888061:AXF15_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/888061:AXF15_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/888061:AXF15_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/888061:AXF15_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC2 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/888061:AXF15_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/888061:AXF15_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A109W5S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/888061:AXF15_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPG5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A109W5B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/888061:AXF15_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A109W6B0 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/888061:AXF15_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A0X8JND2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/888061:AXF15_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNE4 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/888061:AXF15_RS06045 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPY1 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/888061:AXF15_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A109W5G4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRY1 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/888061:AXF15_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A120KMW0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNU8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/888061:AXF15_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRC0 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/888061:AXF15_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQJ8 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/888061:AXF15_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQ52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQE7 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A109W5F6 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/888061:AXF15_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A0X8JND9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/888061:AXF15_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A120KNU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/888061:AXF15_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/888061:AXF15_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S49 family.|||Cell inner membrane http://togogenome.org/gene/888061:AXF15_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/888061:AXF15_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNA3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/888061:AXF15_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A0X8JRE9 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/888061:AXF15_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP29 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A109W6E3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/888061:AXF15_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/888061:AXF15_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A0X8JPQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/888061:AXF15_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNW1 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/888061:AXF15_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A120KN13 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/888061:AXF15_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A109W5J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A120KN75 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/888061:AXF15_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNQ6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/888061:AXF15_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A0X8JR36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/888061:AXF15_RS12405 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26C family.|||Periplasm http://togogenome.org/gene/888061:AXF15_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNK9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/888061:AXF15_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A0X8JSK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/888061:AXF15_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/888061:AXF15_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A109W5B9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/888061:AXF15_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A0X8JN82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/888061:AXF15_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0X8JP25 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS13005 ^@ http://purl.uniprot.org/uniprot/A0A0X8JS79 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/888061:AXF15_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A0X8JQR2 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/888061:AXF15_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A109WAK2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/888061:AXF15_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A0X8JNJ3 ^@ Similarity ^@ Belongs to the Skp family.