http://togogenome.org/gene/110368:LOC112045732 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXZ1|||http://purl.uniprot.org/uniprot/A0A6J1MY87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/IRO homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112047814 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCR4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112050386 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHF4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112047649 ^@ http://purl.uniprot.org/uniprot/A0A6J1N682 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/110368:LOC112048143 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/110368:LOC112049265 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCW8 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112046326 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0X5 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112050102 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGC5|||http://purl.uniprot.org/uniprot/A0A6J1NLK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF5 family.|||Nucleus http://togogenome.org/gene/110368:LOC112053204 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST5 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/110368:LOC112048701 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112048105 ^@ http://purl.uniprot.org/uniprot/A0A6J1N087 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM134/TMEM230 family.|||Early endosome|||Endosome|||Involved in trafficking and recycling of synaptic vesicles.|||Late endosome|||Membrane|||autophagosome|||synaptic vesicle|||trans-Golgi network http://togogenome.org/gene/110368:LOC112050593 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCL8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112046504 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1J5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/110368:LOC112049213 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7D5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/110368:LOC112056739 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3A3 family.|||Nucleus http://togogenome.org/gene/110368:LOC112047544 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5T0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112049780 ^@ http://purl.uniprot.org/uniprot/A0A6J1N744 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051979 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFR9|||http://purl.uniprot.org/uniprot/A0A6J1NFU4|||http://purl.uniprot.org/uniprot/A0A6J1NNN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAS family.|||focal adhesion http://togogenome.org/gene/110368:LOC112047473 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5U1 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/110368:LOC112047512 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112043955 ^@ http://purl.uniprot.org/uniprot/A0A0B5L5W5 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Nucleus http://togogenome.org/gene/110368:LOC112053208 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT44 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. http://togogenome.org/gene/110368:LOC112049642 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJS3 ^@ Similarity ^@ Belongs to the SAM50/omp85 family. http://togogenome.org/gene/110368:LOC112045576 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSU1|||http://purl.uniprot.org/uniprot/A0A6J1MSV5|||http://purl.uniprot.org/uniprot/A0A6J1MXD3|||http://purl.uniprot.org/uniprot/A0A6J1MXG1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112047494 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXU4|||http://purl.uniprot.org/uniprot/A0A6J1N0L7|||http://purl.uniprot.org/uniprot/A0A6J1N5W1|||http://purl.uniprot.org/uniprot/A0A6J1NBI8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058438 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB78 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily. http://togogenome.org/gene/110368:LOC112047479 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF2/ABP1 family.|||nucleolus http://togogenome.org/gene/110368:LOC112051793 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF21 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/110368:LOC112043479 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112043234 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN29 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/110368:LOC112049005 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/110368:LOC112050531 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/110368:LOC112043547 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPI9|||http://purl.uniprot.org/uniprot/A0A6J1MWB8 ^@ Similarity ^@ Belongs to the PA28 family. http://togogenome.org/gene/110368:LOC112045251 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNP1 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/110368:LOC112047483 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5K1|||http://purl.uniprot.org/uniprot/A0A6J1N5U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047853 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCV6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112055670 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3T4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/110368:LOC112049318 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/110368:LOC112046748 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2T3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/110368:LOC112047563 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0U7 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/110368:LOC112050823 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055197 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZY0 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/110368:LOC112043621 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPS2 ^@ Similarity ^@ Belongs to the RRN3 family. http://togogenome.org/gene/110368:LOC112050461 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/110368:LOC112055500 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0W3 ^@ Similarity ^@ Belongs to the PHAF1 family. http://togogenome.org/gene/110368:LOC112047443 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXP6|||http://purl.uniprot.org/uniprot/A0A6J1N0G3 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/110368:LOC112056220 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112054371 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus http://togogenome.org/gene/110368:LOC112045822 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQM5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045351 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWE9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112043325 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/110368:LOC112049061 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC26 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/110368:LOC112047834 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ68|||http://purl.uniprot.org/uniprot/A0A6J1N1W5 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4G family. http://togogenome.org/gene/110368:LOC112053641 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZC7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/110368:LOC112046605 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL51 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112047932 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IWR1/SLC7A6OS family.|||Cytoplasm|||Directs RNA polymerase II nuclear import.|||Nucleus http://togogenome.org/gene/110368:LOC112055652 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV82|||http://purl.uniprot.org/uniprot/A0A6J1NV94 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112048222 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.|||Cell membrane|||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. http://togogenome.org/gene/110368:LOC112050049 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the profilin family.|||Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.|||Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio. http://togogenome.org/gene/110368:LOC112047808 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1T2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112049054 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC11|||http://purl.uniprot.org/uniprot/A0A6J1NC35|||http://purl.uniprot.org/uniprot/A0A6J1NHI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/110368:LOC112045860 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQR9 ^@ Similarity ^@ Belongs to the TMEM9 family. http://togogenome.org/gene/110368:LOC112055281 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTQ6 ^@ Similarity ^@ Belongs to the FAM50 family. http://togogenome.org/gene/110368:LOC112044796 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0Z6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058510 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBM6 ^@ Similarity ^@ Belongs to the small G protein signaling modulator family. http://togogenome.org/gene/110368:LOC112047758 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYW4|||http://purl.uniprot.org/uniprot/A0A6J1N1L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112053778 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMG-CoA reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112054343 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/110368:LOC112048340 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEQ1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112051357 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND86|||http://purl.uniprot.org/uniprot/A0A6J1NFJ8|||http://purl.uniprot.org/uniprot/A0A6J1NL70|||http://purl.uniprot.org/uniprot/A0A6J1NR67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM CPSF6/7 family.|||Nucleus http://togogenome.org/gene/110368:LOC112043024 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM65 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/110368:LOC112048134 ^@ http://purl.uniprot.org/uniprot/A0A6J1N339 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112046746 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCC4/mau-2 family.|||Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase.|||nucleoplasm http://togogenome.org/gene/110368:LOC112047418 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXL2|||http://purl.uniprot.org/uniprot/A0A6J1N5N2|||http://purl.uniprot.org/uniprot/A0A6J1NBA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/110368:LOC112049377 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I LYR family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055199 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTH4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112052341 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH72 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112054769 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRT3 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/110368:LOC112050750 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/110368:LOC112052548 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQP2 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/110368:LOC112047372 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB45 ^@ Similarity ^@ Belongs to the CutC family. http://togogenome.org/gene/110368:LOC112052410 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112043691 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWT5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. Torsin subfamily. http://togogenome.org/gene/110368:LOC112049479 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8A8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/110368:LOC112048976 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBN7 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/110368:LOC112043067 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMC9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/110368:LOC112049721 ^@ http://purl.uniprot.org/uniprot/A0A6J1NET7 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/110368:LOC112046931 ^@ http://purl.uniprot.org/uniprot/A0A6J1N350 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112047627 ^@ http://purl.uniprot.org/uniprot/A0A6J1N651 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112047860 ^@ http://purl.uniprot.org/uniprot/A0A6J1N712 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB4 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.|||Nucleus|||Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7. http://togogenome.org/gene/110368:LOC112049938 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKX0 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/110368:LOC112048236 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8X6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112053195 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT28 ^@ Similarity ^@ Belongs to the LovG family. http://togogenome.org/gene/110368:LOC112058557 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBH4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/110368:LOC112056562 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF2BP family.|||Nucleus http://togogenome.org/gene/110368:LOC112054872 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV25 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/110368:LOC112043414 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/110368:LOC112058617 ^@ http://purl.uniprot.org/uniprot/A0A6J1PCC3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045360 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112056423 ^@ http://purl.uniprot.org/uniprot/A0A6J1P356 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112045282 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNN7|||http://purl.uniprot.org/uniprot/A0A6J1MW42 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAD-like hydrolase superfamily. EYA family.|||Binds 1 Mg(2+) ion per subunit.|||Nucleus http://togogenome.org/gene/110368:LOC112047066 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST4 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/110368:LOC112049886 ^@ http://purl.uniprot.org/uniprot/A0A0B5L3T7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112046314 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6T3 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/110368:LOC112044941 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1J3 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/110368:LOC112044481 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112043977 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLV6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051400 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLC8 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/110368:LOC112046777 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUJ7|||http://purl.uniprot.org/uniprot/A0A6J1N2J0|||http://purl.uniprot.org/uniprot/A0A6J1N8G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane|||Required presynaptically at the neuromuscular junction. Implicated in synaptic vesicle endocytosis. http://togogenome.org/gene/110368:LOC112045433 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112054274 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112056735 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5C0 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/110368:LOC112052200 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/110368:LOC112048016 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7X6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/110368:LOC112051550 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||cytoskeleton http://togogenome.org/gene/110368:LOC112054632 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112048244 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3M1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112054697 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/110368:LOC112049341 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GAR1 family.|||Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).|||Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.|||nucleolus http://togogenome.org/gene/110368:LOC112053566 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVJ0 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/110368:LOC112051044 ^@ http://purl.uniprot.org/uniprot/A0A0B5L3T3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112044379 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112047924 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZI8 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/110368:LOC112044077 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJG1|||http://purl.uniprot.org/uniprot/A0A6J1MYD5|||http://purl.uniprot.org/uniprot/A0A6J1MYD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Cytoplasm|||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity. http://togogenome.org/gene/110368:LOC112048847 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/110368:LOC112047592 ^@ http://purl.uniprot.org/uniprot/A0A6J1N678 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/110368:LOC112046491 ^@ http://purl.uniprot.org/uniprot/A0A6J1N166 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFB10 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112052464 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK61 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/110368:LOC112045050 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVH9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112048800 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112047303 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Z3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/110368:LOC112048825 ^@ http://purl.uniprot.org/uniprot/A0A6J1N320 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPF27 family.|||Nucleus http://togogenome.org/gene/110368:LOC112049740 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6Y7|||http://purl.uniprot.org/uniprot/A0A6J1NK63|||http://purl.uniprot.org/uniprot/A0A6J1NK90 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family.|||Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. http://togogenome.org/gene/110368:LOC112051880 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052026 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFX4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/110368:LOC112057909 ^@ http://purl.uniprot.org/uniprot/A0A6J1P915 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/110368:LOC112043302 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGU4 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/110368:LOC112043374 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJH8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112056595 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4S9|||http://purl.uniprot.org/uniprot/A0A6J1P4T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/110368:LOC112047434 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBB6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/110368:LOC112047922 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051708 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112048857 ^@ http://purl.uniprot.org/uniprot/A0A6J1N633|||http://purl.uniprot.org/uniprot/A0A6J1NBD3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/110368:LOC112052754 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSB9 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/110368:LOC112051994 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049401 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5A7 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/110368:LOC112057940 ^@ http://purl.uniprot.org/uniprot/A0A6J1P924 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049353 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7W7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112046809 ^@ http://purl.uniprot.org/uniprot/A0A6J1N330 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/110368:LOC112045346 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WRB/GET1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112050936 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus http://togogenome.org/gene/110368:LOC112043732 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the COQ10 family.|||Interacts with coenzyme Q.|||Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes. http://togogenome.org/gene/110368:LOC112044510 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTB0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/110368:LOC112045260 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2L7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/110368:LOC112052997 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJT7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/110368:LOC112044646 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTP7 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/110368:LOC112057102 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6F7 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/110368:LOC112050346 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112057943 ^@ http://purl.uniprot.org/uniprot/A0A6J1P954 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the flavin monoamine oxidase family.|||Histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.|||Nucleus http://togogenome.org/gene/110368:LOC112051222 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF30 ^@ Similarity ^@ Belongs to the HGH1 family. http://togogenome.org/gene/110368:LOC112044392 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/110368:LOC112056552 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4M8 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112049175 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4E8 ^@ Similarity ^@ Belongs to the OPI10 family. http://togogenome.org/gene/110368:LOC112054487 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.|||Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112053417 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYR4 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/110368:LOC112050648 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIB6|||http://purl.uniprot.org/uniprot/A0A6J1NNG8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112051829 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNC0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.|||Belongs to the carbohydrate kinase PfkB family.|||Binds 3 Mg(2+) ions per subunit.|||Monomer.|||Nucleus http://togogenome.org/gene/110368:LOC112058276 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAB1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112049490 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5L2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA13 subunit family.|||Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112058000 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9A6|||http://purl.uniprot.org/uniprot/A0A6J1P9C7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/110368:LOC112057945 ^@ http://purl.uniprot.org/uniprot/A0A6J1P948 ^@ Caution|||Subcellular Location Annotation|||Subunit ^@ Heterodimer of burs and pburs.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/110368:LOC112044641 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0E1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112045932 ^@ http://purl.uniprot.org/uniprot/A0A6J1N575 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/110368:LOC112048768 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2S6|||http://purl.uniprot.org/uniprot/A0A6J1NGH3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058307 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/110368:LOC112045475 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPE5|||http://purl.uniprot.org/uniprot/A0A6J1MSD2|||http://purl.uniprot.org/uniprot/A0A6J1MWX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/110368:LOC112054295 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSK4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050310 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9C9|||http://purl.uniprot.org/uniprot/A0A6J1NBN4|||http://purl.uniprot.org/uniprot/A0A6J1NMF3 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/110368:LOC112044254 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK08 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/110368:LOC112043722 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112046694 ^@ http://purl.uniprot.org/uniprot/A0A6J1N244 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/110368:LOC112046972 ^@ http://purl.uniprot.org/uniprot/A0A6J1N991 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/110368:LOC112045121 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN38 ^@ Similarity ^@ Belongs to the SMIM12 family. http://togogenome.org/gene/110368:LOC112043565 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPL4 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/110368:LOC112052792 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC7 family.|||Nucleus http://togogenome.org/gene/110368:LOC112044359 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GLE1 family.|||Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).|||nuclear pore complex http://togogenome.org/gene/110368:LOC112055458 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT9 family.|||P-body http://togogenome.org/gene/110368:LOC112052289 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/110368:LOC112058567 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphatidyl serine synthase family.|||Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112057948 ^@ http://purl.uniprot.org/uniprot/A0A6J1P959 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/110368:LOC112043233 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNC9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046292 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVT6 ^@ Similarity ^@ Belongs to the GORAB family. http://togogenome.org/gene/110368:LOC112049700 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6Q5|||http://purl.uniprot.org/uniprot/A0A6J1N981|||http://purl.uniprot.org/uniprot/A0A6J1NEP3|||http://purl.uniprot.org/uniprot/A0A6J1NEP8|||http://purl.uniprot.org/uniprot/A0A6J1NJZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112046214 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSE7|||http://purl.uniprot.org/uniprot/A0A6J1N055|||http://purl.uniprot.org/uniprot/A0A6J1N0H2|||http://purl.uniprot.org/uniprot/A0A6J1N6F1 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/110368:LOC112054853 ^@ http://purl.uniprot.org/uniprot/A0A6J1P088 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/110368:LOC112043195 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase IV family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055634 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY36 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112043520 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047400 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0B2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112057740 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8J6 ^@ Function|||Similarity|||Subunit ^@ Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.|||Belongs to the cyclin family. Cyclin C subfamily.|||Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. http://togogenome.org/gene/110368:LOC112054289 ^@ http://purl.uniprot.org/uniprot/A0A6J1P165 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/110368:LOC112052899 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB7 subunit family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/110368:LOC112047524 ^@ http://purl.uniprot.org/uniprot/A0A6J1N605 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112049196 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCN2|||http://purl.uniprot.org/uniprot/A0A6J1NI15 ^@ Caution|||Similarity ^@ Belongs to the RAB6IP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112045174 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112045387 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP29 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049325 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane http://togogenome.org/gene/110368:LOC112058575 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBM7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/110368:LOC112043445 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||nucleolus http://togogenome.org/gene/110368:LOC112048123 ^@ http://purl.uniprot.org/uniprot/A0A6J1N853|||http://purl.uniprot.org/uniprot/A0A6J1N8D9 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/110368:LOC112048764 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAZ5 ^@ Similarity ^@ Belongs to the scoloptoxin-05 family. http://togogenome.org/gene/110368:LOC112051528 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGB5 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/110368:LOC112051992 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047847 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1Y4|||http://purl.uniprot.org/uniprot/A0A6J1N776 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112050506 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/110368:LOC112056476 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP17 family.|||nucleolus http://togogenome.org/gene/110368:LOC112049613 ^@ http://purl.uniprot.org/uniprot/A0A6J1N687|||http://purl.uniprot.org/uniprot/A0A6J1N8W6|||http://purl.uniprot.org/uniprot/A0A6J1N8X0|||http://purl.uniprot.org/uniprot/A0A6J1N8X4|||http://purl.uniprot.org/uniprot/A0A6J1NE97|||http://purl.uniprot.org/uniprot/A0A6J1NEA3|||http://purl.uniprot.org/uniprot/A0A6J1NEE0|||http://purl.uniprot.org/uniprot/A0A6J1NJM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/110368:LOC112046845 ^@ http://purl.uniprot.org/uniprot/A0A6J1N374 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SCOC family.|||Positive regulator of amino acid starvation-induced autophagy.|||trans-Golgi network http://togogenome.org/gene/110368:LOC112055201 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTH9|||http://purl.uniprot.org/uniprot/A0A6J1NWA3|||http://purl.uniprot.org/uniprot/A0A6J1P190|||http://purl.uniprot.org/uniprot/A0A6J1P307 ^@ Similarity ^@ Belongs to the FAM76 family. http://togogenome.org/gene/110368:LOC112049531 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARMET family.|||Secreted http://togogenome.org/gene/110368:LOC112050979 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJS0 ^@ Function ^@ Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. http://togogenome.org/gene/110368:LOC112045959 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||Nucleus http://togogenome.org/gene/110368:LOC112054188 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/110368:LOC112044281 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/110368:LOC112044399 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the organo anion transporter (TC 2.A.60) family.|||Membrane http://togogenome.org/gene/110368:LOC112053326 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYG9 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/110368:LOC112053349 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF-beta family.|||Nucleus http://togogenome.org/gene/110368:LOC112048324 ^@ http://purl.uniprot.org/uniprot/A0A6J1N998 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG9 family.|||Membrane|||Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.|||Preautophagosomal structure membrane http://togogenome.org/gene/110368:LOC112043391 ^@ http://purl.uniprot.org/uniprot/A0A6J1MH69 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058236 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.|||Cytoplasm|||Heterodimer of a catalytic subunit and an accessory subunit. http://togogenome.org/gene/110368:LOC112056456 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0X3 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/110368:LOC112053859 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWS4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/110368:LOC112052951 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112048951 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3H3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112053952 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112050843 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SYF2 family.|||Involved in pre-mRNA splicing.|||May be part of a spliceosome complex.|||Nucleus http://togogenome.org/gene/110368:LOC112053528 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLV4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the citrate synthase family.|||Homodimer.|||Mitochondrion matrix http://togogenome.org/gene/110368:LOC112058558 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBT1 ^@ Function|||Similarity ^@ Belongs to the MGR2 family.|||Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.|||Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. http://togogenome.org/gene/110368:LOC112047824 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCS3 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/110368:LOC112050337 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9F9|||http://purl.uniprot.org/uniprot/A0A6J1NMI2 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/110368:LOC112043324 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/110368:LOC112051227 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF32 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/110368:LOC112054334 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ82|||http://purl.uniprot.org/uniprot/A0A6J1P1B4 ^@ Subcellular Location Annotation ^@ Membrane|||adherens junction|||cytoskeleton http://togogenome.org/gene/110368:LOC112055176 ^@ http://purl.uniprot.org/uniprot/A0A6J1P169 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/110368:LOC112043068 ^@ http://purl.uniprot.org/uniprot/A0A6J1MID2 ^@ Function|||Similarity ^@ Belongs to the SAP18 family.|||Involved in the tethering of the SIN3 complex to core histone proteins. http://togogenome.org/gene/110368:LOC112047650 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC32 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/110368:LOC112044362 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKD2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/110368:LOC112053052 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK09 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112052008 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNP8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112050649 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Belongs to the scoloptoxin-05 family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112043431 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVV0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051916 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNQ4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anamorsin family.|||Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion intermembrane space|||Monomer.|||The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.|||The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.|||The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space. http://togogenome.org/gene/110368:LOC112052445 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHS7 ^@ Similarity ^@ Belongs to the TDD superfamily. DTWD2 family. http://togogenome.org/gene/110368:LOC112055677 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVA5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112052918 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112049111 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCA3|||http://purl.uniprot.org/uniprot/A0A6J1NCC8 ^@ Similarity ^@ Belongs to the DIP2 family. http://togogenome.org/gene/110368:LOC112045571 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSR6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/110368:LOC112043463 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHD4 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/110368:LOC112058429 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/110368:LOC112057048 ^@ http://purl.uniprot.org/uniprot/A0A6J1P687 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112057041 ^@ http://purl.uniprot.org/uniprot/A0A6J1P630 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112046273 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0F8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112057260 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6S0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/110368:LOC112046287 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112043891 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXP4 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/110368:LOC112046429 ^@ http://purl.uniprot.org/uniprot/A0A6J1N193 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112046679 ^@ http://purl.uniprot.org/uniprot/A0A6J1N808 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050537 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCF3 ^@ Similarity ^@ Belongs to the pinin family. http://togogenome.org/gene/110368:LOC112047604 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Catalyzes juvenile hormone hydrolysis.|||Endoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112057666 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/110368:LOC112051650 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/110368:LOC112058101 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA18 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112052630 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRR6|||http://purl.uniprot.org/uniprot/A0A6J1NRS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM11 family.|||Membrane|||Plays a role in mitochondrial morphogenesis. http://togogenome.org/gene/110368:LOC112043576 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPM1 ^@ Similarity ^@ Belongs to the CDK5RAP3 family. http://togogenome.org/gene/110368:LOC112057659 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGX family.|||Endoplasmic reticulum membrane|||Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. http://togogenome.org/gene/110368:LOC112043824 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQL0 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/110368:LOC112047794 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ08|||http://purl.uniprot.org/uniprot/A0A6J1NCN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/110368:LOC112052462 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQC2 ^@ Function|||Similarity ^@ Belongs to the APC10 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/110368:LOC112055370 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWW4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045805 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQK4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/110368:LOC112048116 ^@ http://purl.uniprot.org/uniprot/A0A6J1N095 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CISD protein family. CISD2 subfamily.|||Binds 1 [2Fe-2S] cluster.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112051884 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNK4 ^@ Function|||Similarity ^@ Belongs to the TCTP family.|||Involved in calcium binding and microtubule stabilization. http://togogenome.org/gene/110368:LOC112044234 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/110368:LOC112046943 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG28 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112043223 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM234 family.|||Membrane http://togogenome.org/gene/110368:LOC112044160 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJQ2 ^@ Similarity ^@ Belongs to the CFAP157 family. http://togogenome.org/gene/110368:LOC112055655 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112051744 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMV4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112042817 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLX5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112050825 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIW3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.|||Interacts with UQCRFS1.|||Mitochondrion matrix http://togogenome.org/gene/110368:LOC112049608 ^@ http://purl.uniprot.org/uniprot/A0A6J1N679 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Membrane http://togogenome.org/gene/110368:LOC112047210 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|||Cytoplasm|||Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. http://togogenome.org/gene/110368:LOC112043159 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUT3 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/110368:LOC112044871 ^@ http://purl.uniprot.org/uniprot/A0A6J1N195 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/110368:LOC112047307 ^@ http://purl.uniprot.org/uniprot/A0A6J1N569 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044635 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DDB1 family.|||Cytoplasm|||Nucleus|||Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair. http://togogenome.org/gene/110368:LOC112048342 ^@ http://purl.uniprot.org/uniprot/A0A6J1N178 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112045362 ^@ http://purl.uniprot.org/uniprot/A0A6J1N307 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044304 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMZ7 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/110368:LOC112043733 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGN3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112043499 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK12 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/110368:LOC112043668 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNU66/SART1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112045259 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/110368:LOC112045345 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNY1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/110368:LOC112054595 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat shock protein 70 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/110368:LOC112044034 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRM1 ^@ Function|||Similarity ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. http://togogenome.org/gene/110368:LOC112047698 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCA1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112048506 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9Q9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112043428 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVU5 ^@ Function|||Similarity ^@ Belongs to the WD repeat ARPC1 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. http://togogenome.org/gene/110368:LOC112049503 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5R6|||http://purl.uniprot.org/uniprot/A0A6J1N5S1|||http://purl.uniprot.org/uniprot/A0A6J1N5T3|||http://purl.uniprot.org/uniprot/A0A6J1NDT6|||http://purl.uniprot.org/uniprot/A0A6J1NDU7|||http://purl.uniprot.org/uniprot/A0A6J1NDV3|||http://purl.uniprot.org/uniprot/A0A6J1NDV9|||http://purl.uniprot.org/uniprot/A0A6J1NDX8|||http://purl.uniprot.org/uniprot/A0A6J1NDY3|||http://purl.uniprot.org/uniprot/A0A6J1NDY9|||http://purl.uniprot.org/uniprot/A0A6J1NDZ3|||http://purl.uniprot.org/uniprot/A0A6J1NJ85|||http://purl.uniprot.org/uniprot/A0A6J1NJ93|||http://purl.uniprot.org/uniprot/A0A6J1NJ98|||http://purl.uniprot.org/uniprot/A0A6J1NJA2 ^@ Similarity ^@ Belongs to the tropomyosin family. http://togogenome.org/gene/110368:LOC112051873 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN56 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/110368:LOC112048214 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8M5 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/110368:LOC112045280 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRN0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/110368:LOC112045159 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the USE1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112047772 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1N6|||http://purl.uniprot.org/uniprot/A0A6J1N6X7 ^@ Subcellular Location Annotation ^@ Nucleus|||perinuclear region http://togogenome.org/gene/110368:LOC112053825 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRB/QCR7 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112049772 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2B alpha/beta/delta subunits family.|||Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.|||Complex of five different subunits; alpha, beta, gamma, delta and epsilon. http://togogenome.org/gene/110368:LOC112044980 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1N7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112052960 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS61 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/110368:LOC112052781 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/110368:LOC112046103 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZW6 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/110368:LOC112054682 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dystrophin family. Dystrobrevin subfamily.|||Cytoplasm http://togogenome.org/gene/110368:LOC112052181 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU95 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family.|||Mammalian complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112057942 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9E6 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/110368:LOC112045908 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYP6|||http://purl.uniprot.org/uniprot/A0A6J1MZ01 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049546 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJE2 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/110368:LOC112055651 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3S6 ^@ Subcellular Location Annotation ^@ adherens junction http://togogenome.org/gene/110368:LOC112055509 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUP3|||http://purl.uniprot.org/uniprot/A0A6J1NXJ6|||http://purl.uniprot.org/uniprot/A0A6J1P230 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112052490 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHZ1 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/110368:LOC112049764 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKA0 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine. http://togogenome.org/gene/110368:LOC112049528 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8L8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112058579 ^@ http://purl.uniprot.org/uniprot/A0A6J1PC84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDCD10 family.|||Cytoplasm|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112048374 ^@ http://purl.uniprot.org/uniprot/A0A6J1N434|||http://purl.uniprot.org/uniprot/A0A6J1NEV4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112048824 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5Y3 ^@ Similarity ^@ Belongs to the peptidase C65 family. http://togogenome.org/gene/110368:LOC112053841 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN75|||http://purl.uniprot.org/uniprot/A0A6J1NQS4|||http://purl.uniprot.org/uniprot/A0A6J1NWN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112042792 ^@ http://purl.uniprot.org/uniprot/A0A6J1MF67|||http://purl.uniprot.org/uniprot/A0A6J1MTA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112048580 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFT7 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/110368:LOC112051441 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRH5 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/110368:LOC112057965 ^@ http://purl.uniprot.org/uniprot/A0A6J1P913 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-L/IML3 family.|||Nucleus http://togogenome.org/gene/110368:LOC112058403 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/110368:LOC112058085 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112047917 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047911 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051898 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN97|||http://purl.uniprot.org/uniprot/A0A6J1NT58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112051866 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/110368:LOC112057747 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS5 family.|||Membrane|||centriolar satellite|||cilium membrane http://togogenome.org/gene/110368:LOC112048597 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/110368:LOC112048948 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/110368:LOC112050532 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Late endosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112049506 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/110368:LOC112050986 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPS9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112045115 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR53|||http://purl.uniprot.org/uniprot/A0A6J1MVS2 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/110368:LOC112046554 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMC family.|||Membrane http://togogenome.org/gene/110368:LOC112045053 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112043747 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ96 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047343 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits. http://togogenome.org/gene/110368:LOC112043709 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI47 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. http://togogenome.org/gene/110368:LOC112058287 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.|||Peroxisome http://togogenome.org/gene/110368:LOC112052174 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.|||Cytoplasm|||Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. http://togogenome.org/gene/110368:LOC112047136 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA53 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112053689 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/110368:LOC112052469 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHW1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046974 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3B0 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/110368:LOC112052851 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLN9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112049013 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits. http://togogenome.org/gene/110368:LOC112045278 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2N7 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/110368:LOC112055143 ^@ http://purl.uniprot.org/uniprot/A0A6J1P141 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/110368:LOC112043552 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112055792 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVP0 ^@ Similarity ^@ Belongs to the Integrator subunit 3 family. http://togogenome.org/gene/110368:LOC112043086 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIF7|||http://purl.uniprot.org/uniprot/A0A6J1MII0|||http://purl.uniprot.org/uniprot/A0A6J1MMW0 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/110368:LOC112048067 ^@ http://purl.uniprot.org/uniprot/A0A6J1N036 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112043720 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ56 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/110368:LOC112043402 ^@ http://purl.uniprot.org/uniprot/A0A6J1MH75|||http://purl.uniprot.org/uniprot/A0A6J1MVR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/110368:LOC112046848 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2T9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/110368:LOC112057699 ^@ http://purl.uniprot.org/uniprot/A0A6J1P807|||http://purl.uniprot.org/uniprot/A0A6J1P811|||http://purl.uniprot.org/uniprot/A0A6J1P818|||http://purl.uniprot.org/uniprot/A0A6J1P823|||http://purl.uniprot.org/uniprot/A0A6J1P832|||http://purl.uniprot.org/uniprot/A0A6J1P866|||http://purl.uniprot.org/uniprot/A0A6J1P871|||http://purl.uniprot.org/uniprot/A0A6J1P8D6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112054984 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112045326 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRU2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112051273 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQW0 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/110368:LOC112057927 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9C6 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/110368:LOC112043147 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGC1|||http://purl.uniprot.org/uniprot/A0A6J1MIN3|||http://purl.uniprot.org/uniprot/A0A6J1MN28|||http://purl.uniprot.org/uniprot/A0A6J1MUR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054335 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/110368:LOC112055968 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZE2|||http://purl.uniprot.org/uniprot/A0A6J1P373 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112044170 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044412 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNB5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/110368:LOC112043931 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR39 ^@ Function ^@ May play an important role in spermatogenesis and/or testis development. http://togogenome.org/gene/110368:LOC112054065 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXL5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112048496 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4H6 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/110368:LOC112047440 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112046787 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAP-alpha family.|||Endoplasmic reticulum membrane|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. http://togogenome.org/gene/110368:LOC112053733 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 30 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/110368:LOC112053740 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQE2 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/110368:LOC112051577 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the translin family.|||DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.|||Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.|||Nucleus|||Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring. http://togogenome.org/gene/110368:LOC112043095 ^@ http://purl.uniprot.org/uniprot/A0A6J1MG59 ^@ Similarity ^@ Belongs to the G protein gamma family. http://togogenome.org/gene/110368:LOC112047663 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRK1 family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112043996 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRN7/TAF1B family.|||nucleolus http://togogenome.org/gene/110368:LOC112042878 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the U1 small nuclear ribonucleoprotein C family.|||Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.|||Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.|||Nucleus|||U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. http://togogenome.org/gene/110368:LOC112046719 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2P7 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112044365 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG2 family.|||Endoplasmic reticulum membrane|||Lipid droplet|||Preautophagosomal structure membrane http://togogenome.org/gene/110368:LOC112044575 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNY7 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/110368:LOC112056421 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0U4|||http://purl.uniprot.org/uniprot/A0A6J1P3X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112052066 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG42|||http://purl.uniprot.org/uniprot/A0A6J1NTT3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112044953 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQJ3|||http://purl.uniprot.org/uniprot/A0A6J1MV50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043020 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044491 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thymosin beta family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112055494 ^@ http://purl.uniprot.org/uniprot/A0A6J1P212 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.|||Nucleus http://togogenome.org/gene/110368:LOC112043961 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRD4|||http://purl.uniprot.org/uniprot/A0A6J1MXZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light intermediate chain family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112043976 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGG2|||http://purl.uniprot.org/uniprot/A0A6J1MLW5|||http://purl.uniprot.org/uniprot/A0A6J1MRB9|||http://purl.uniprot.org/uniprot/A0A6J1MRC8|||http://purl.uniprot.org/uniprot/A0A6J1MY54 ^@ Similarity ^@ Belongs to the TPRG1 family. http://togogenome.org/gene/110368:LOC112043405 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNU1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058387 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAX6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048592 ^@ http://purl.uniprot.org/uniprot/A0A6J1N540 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/110368:LOC112050296 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054724 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Cytoplasm|||Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.|||Monomer. http://togogenome.org/gene/110368:LOC112058116 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Cytoplasm|||LSm subunits form a heteromer with a donut shape.|||P-body|||Probably involved with other LSm subunits in the general process of degradation of mRNAs. http://togogenome.org/gene/110368:LOC112051435 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRM NCBP2 family.|||Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.|||Component of the nuclear cap-binding complex (CBC), a heterodimer composed of Cbp80 and Cbp20 that interacts with m7GpppG-capped RNA.|||Nucleus http://togogenome.org/gene/110368:LOC112044661 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTX4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/110368:LOC112051820 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMZ4 ^@ Similarity ^@ Belongs to the BLOC1S1 family. http://togogenome.org/gene/110368:LOC112043433 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNY4|||http://purl.uniprot.org/uniprot/A0A6J1MP18|||http://purl.uniprot.org/uniprot/A0A6J1MVV5 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/110368:LOC112045833 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQN3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057933 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9D1 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/110368:LOC112053524 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112048241 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0U6 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112047908 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZG2|||http://purl.uniprot.org/uniprot/A0A6J1N781 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043616 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKE9 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/110368:LOC112044636 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP68|||http://purl.uniprot.org/uniprot/A0A6J1MTT2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052705 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS12|||http://purl.uniprot.org/uniprot/A0A6J1NW67 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/110368:LOC112048745 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052158 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPR8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/110368:LOC112048839 ^@ http://purl.uniprot.org/uniprot/A0A6J1N342 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Peroxisome matrix|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. http://togogenome.org/gene/110368:LOC112054720 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRM3 ^@ Similarity ^@ Belongs to the Asterix family. http://togogenome.org/gene/110368:LOC112047053 ^@ http://purl.uniprot.org/uniprot/A0A6J1N418 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112052259 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUK0 ^@ Similarity ^@ Belongs to the GAMAD family. http://togogenome.org/gene/110368:LOC112048492 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane http://togogenome.org/gene/110368:LOC112044348 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN51 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/110368:LOC112051211 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF15 ^@ Similarity ^@ Belongs to the UPF0488 family. http://togogenome.org/gene/110368:LOC112048347 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEQ9 ^@ Similarity ^@ Belongs to the pyrokinin family. http://togogenome.org/gene/110368:LOC112043011 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAK10 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112058238 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA41 ^@ Similarity ^@ Belongs to the NC2 beta/DR1 family. http://togogenome.org/gene/110368:LOC112055483 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUK6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043418 ^@ http://purl.uniprot.org/uniprot/A0A6J1MH91 ^@ Function|||Subcellular Location Annotation ^@ Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112049144 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/110368:LOC112049844 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/110368:LOC112055852 ^@ http://purl.uniprot.org/uniprot/A0A6J1P425 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112050514 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/110368:LOC112043093 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/110368:LOC112053876 ^@ http://purl.uniprot.org/uniprot/A0A6J1P033 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit H family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112048299 ^@ http://purl.uniprot.org/uniprot/A0A6J1N967 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/110368:LOC112056414 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/110368:LOC112045504 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPG4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046982 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVE4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/110368:LOC112055807 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3Z1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/110368:LOC112047595 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112051923 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFJ2 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/110368:LOC112048782 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5T8|||http://purl.uniprot.org/uniprot/A0A6J1NAY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/110368:LOC112049705 ^@ http://purl.uniprot.org/uniprot/A0A6J1NER1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/110368:LOC112048724 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112049075 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC70 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112045464 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSB5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/110368:LOC112047344 ^@ http://purl.uniprot.org/uniprot/A0A6J1N534 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/110368:LOC112046482 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1G4 ^@ Similarity ^@ Belongs to the pym family. http://togogenome.org/gene/110368:LOC112051731 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH84|||http://purl.uniprot.org/uniprot/A0A6J1NMR1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/110368:LOC112048162 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE22 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/110368:LOC112043031 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM74 ^@ Similarity ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family. http://togogenome.org/gene/110368:LOC112058373 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAS3 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/110368:LOC112053494 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOSIP family.|||Nucleus http://togogenome.org/gene/110368:LOC112054041 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRN9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112048814 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5X4 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/110368:LOC112043783 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX73 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/110368:LOC112044079 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRQ0|||http://purl.uniprot.org/uniprot/A0A6J1MRR5 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/110368:LOC112047921 ^@ http://purl.uniprot.org/uniprot/A0A6J1N798 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049364 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7X8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/110368:LOC112053652 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUQ8 ^@ Similarity ^@ Belongs to the dpy-30 family. http://togogenome.org/gene/110368:LOC112054267 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSH4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112051764 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMU3 ^@ Similarity ^@ Belongs to the palmitoyl-protein thioesterase family. http://togogenome.org/gene/110368:LOC112052877 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRW5 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1. http://togogenome.org/gene/110368:LOC112049128 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHU2 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/110368:LOC112052304 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPS6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/110368:LOC112044479 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKS9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112049288 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/110368:LOC112053520 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU93 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/110368:LOC112054361 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQC4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112045512 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPH5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112047408 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0C1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050925 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJJ3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049505 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8H4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112051194 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKG9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/110368:LOC112044364 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSS1 ^@ Caution|||Subcellular Location Annotation ^@ Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112058502 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBZ0 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112047404 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0B7 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/110368:LOC112051207 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/110368:LOC112048968 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBR7 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.|||Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8. http://togogenome.org/gene/110368:LOC112044808 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUI9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/110368:LOC112044645 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP75 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/110368:LOC112057768 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B5 ^@ Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/110368:LOC112049406 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLU7 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/110368:LOC112043173 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/110368:LOC112051097 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/110368:LOC112045328 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWC5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/110368:LOC112057979 ^@ http://purl.uniprot.org/uniprot/A0A6J1P935|||http://purl.uniprot.org/uniprot/A0A6J1P941|||http://purl.uniprot.org/uniprot/A0A6J1P967|||http://purl.uniprot.org/uniprot/A0A6J1P972|||http://purl.uniprot.org/uniprot/A0A6J1P988|||http://purl.uniprot.org/uniprot/A0A6J1P996|||http://purl.uniprot.org/uniprot/A0A6J1P9A0|||http://purl.uniprot.org/uniprot/A0A6J1P9I7|||http://purl.uniprot.org/uniprot/A0A6J1P9J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the potassium channel HCN family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112050439 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM198 family.|||Membrane http://togogenome.org/gene/110368:LOC112046875 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUX2 ^@ Similarity ^@ Belongs to the heme oxygenase family. http://togogenome.org/gene/110368:LOC112051912 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT73 ^@ Similarity ^@ Belongs to the NKAP family. http://togogenome.org/gene/110368:LOC112049487 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5K6|||http://purl.uniprot.org/uniprot/A0A6J1NDS2 ^@ Similarity ^@ Belongs to the KHDC4 family. http://togogenome.org/gene/110368:LOC112053938 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCRQ/QCR8 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046520 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1B8 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112048346 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3Z8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/110368:LOC112048884 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B4 family.|||Nucleus http://togogenome.org/gene/110368:LOC112046675 ^@ http://purl.uniprot.org/uniprot/A0A6J1N206|||http://purl.uniprot.org/uniprot/A0A6J1N7Z8 ^@ Similarity ^@ Belongs to the zygin family. http://togogenome.org/gene/110368:LOC112043016 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112044441 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKM6 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/110368:LOC112054358 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/110368:LOC112053351 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FBXO45/Fsn family.|||Synapse http://togogenome.org/gene/110368:LOC112048763 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAU1 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/110368:LOC112052068 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPD2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/110368:LOC112044374 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSS5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/110368:LOC112058360 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB60 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/110368:LOC112043314 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJ93 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20A family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/110368:LOC112043586 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPK9 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/110368:LOC112049678 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEL7|||http://purl.uniprot.org/uniprot/A0A6J1P6A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049981 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 31 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112054820 ^@ http://purl.uniprot.org/uniprot/A0A6J1P050 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112045926 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR17|||http://purl.uniprot.org/uniprot/A0A6J1MR22|||http://purl.uniprot.org/uniprot/A0A6J1MU77|||http://purl.uniprot.org/uniprot/A0A6J1MZ27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Membrane http://togogenome.org/gene/110368:LOC112046718 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUC0|||http://purl.uniprot.org/uniprot/A0A6J1MXB5|||http://purl.uniprot.org/uniprot/A0A6J1N2A1|||http://purl.uniprot.org/uniprot/A0A6J1N882 ^@ Similarity ^@ Belongs to the PIAS family. http://togogenome.org/gene/110368:LOC112044458 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112052361 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQL4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112057662 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7V3|||http://purl.uniprot.org/uniprot/A0A6J1P7W0|||http://purl.uniprot.org/uniprot/A0A6J1P7X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112053221 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKQ2|||http://purl.uniprot.org/uniprot/A0A6J1NT67 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112053328 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNI3 ^@ Similarity ^@ Belongs to the TPA1 family. http://togogenome.org/gene/110368:LOC112050555 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCH1 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/110368:LOC112046089 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZV0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/110368:LOC112049701 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK01 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/110368:LOC112048475 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFA2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/110368:LOC112056687 ^@ http://purl.uniprot.org/uniprot/A0A6J1P562 ^@ Similarity ^@ Belongs to the ABI family. http://togogenome.org/gene/110368:LOC112056342 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112053998 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112045679 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXS6 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/110368:LOC112051397 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL50 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112051658 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGT7|||http://purl.uniprot.org/uniprot/A0A6J1NMJ0 ^@ Similarity ^@ Belongs to the cAMP-dependent kinase regulatory chain family. http://togogenome.org/gene/110368:LOC112043636 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPT5 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/110368:LOC112050917 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDV6 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/110368:LOC112049640 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEF4 ^@ Function|||Subcellular Location Annotation ^@ Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Membrane|||Mitochondrion inner membrane|||Nucleus http://togogenome.org/gene/110368:LOC112046854 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXW9 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/110368:LOC112046836 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112051221 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF25|||http://purl.uniprot.org/uniprot/A0A6J1NKT6|||http://purl.uniprot.org/uniprot/A0A6J1NQN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcription factor STAT family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112054556 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTS6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112056105 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2F3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053522 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLU4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112055033 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVN4 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/110368:LOC112051232 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQQ6 ^@ Similarity ^@ Belongs to the peroxin-13 family. http://togogenome.org/gene/110368:LOC112048245 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0V1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112047499 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 7B2 family.|||Secreted http://togogenome.org/gene/110368:LOC112044525 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTB8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058414 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM256 family.|||Membrane http://togogenome.org/gene/110368:LOC112057991 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9B3 ^@ Similarity ^@ Belongs to the RRM TRSPAP family. http://togogenome.org/gene/110368:LOC112053821 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWK1 ^@ Similarity ^@ Belongs to the PTPS family. http://togogenome.org/gene/110368:LOC112051507 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112049384 ^@ http://purl.uniprot.org/uniprot/A0A6J1N581|||http://purl.uniprot.org/uniprot/A0A6J1N7Z7 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/110368:LOC112055674 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112054955 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ATPase subunit F6 family.|||Membrane|||Mitochondrion http://togogenome.org/gene/110368:LOC112044388 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZH7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112048501 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9W9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050223 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecE/SEC61-gamma family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112053759 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MYST (SAS/MOZ) family.|||Nucleus http://togogenome.org/gene/110368:LOC112051766 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSQ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. http://togogenome.org/gene/110368:LOC112056375 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112048145 ^@ http://purl.uniprot.org/uniprot/A0A6J1N355 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nudE family.|||centrosome|||spindle http://togogenome.org/gene/110368:LOC112055963 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZD3 ^@ Similarity ^@ Belongs to the DNA photolyase class-2 family. http://togogenome.org/gene/110368:LOC112043991 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112054230 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY88 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/110368:LOC112051588 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRI3 family.|||Membrane|||perinuclear region http://togogenome.org/gene/110368:LOC112052467 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQD0 ^@ Similarity ^@ Belongs to the selenoprotein M/F family. http://togogenome.org/gene/110368:LOC112046347 ^@ http://purl.uniprot.org/uniprot/A0A6J1N116 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/110368:LOC112050922 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/110368:LOC112046599 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTT1 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/110368:LOC112057693 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||perinuclear region http://togogenome.org/gene/110368:LOC112043127 ^@ http://purl.uniprot.org/uniprot/A0A6J1MG92 ^@ Similarity ^@ Belongs to the acetyltransferase family. NAA60 subfamily. http://togogenome.org/gene/110368:LOC112058264 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAB7 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/110368:LOC112049984 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112053225 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN54 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112046509 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWH1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/110368:LOC112054305 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSQ8 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/110368:LOC112048441 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DONSON family.|||Nucleus http://togogenome.org/gene/110368:LOC112051604 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIc family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112043611 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112054877 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV33 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/110368:LOC112052312 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQD9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MCU (TC 1.A.77) family.|||Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).|||Membrane|||Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046285 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Catalyzes juvenile hormone hydrolysis.|||Endoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112046766 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8D5 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/110368:LOC112050768 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND96 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112047365 ^@ http://purl.uniprot.org/uniprot/A0A6J1N073 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC37 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112047624 ^@ http://purl.uniprot.org/uniprot/A0A6J1N646 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054582 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR54 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CybS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046513 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/110368:LOC112054294 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 11 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112047916 ^@ http://purl.uniprot.org/uniprot/A0A6J1N282 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/110368:LOC112051416 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLE5 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/110368:LOC112043084 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMF4 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/110368:LOC112052037 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUEDC2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112057700 ^@ http://purl.uniprot.org/uniprot/A0A6J1P828 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112046276 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCMBP family.|||Nucleus http://togogenome.org/gene/110368:LOC112048080 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2W2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044854 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ69|||http://purl.uniprot.org/uniprot/A0A6J1MUH6 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/110368:LOC112049633 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/110368:LOC112052909 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJJ6|||http://purl.uniprot.org/uniprot/A0A6J1NWX2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058548 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBK3 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/110368:LOC112055817 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1L6 ^@ Similarity ^@ Belongs to the exportin family. http://togogenome.org/gene/110368:LOC112053942 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSU72 phosphatase family.|||Nucleus|||Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. http://togogenome.org/gene/110368:LOC112051572 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS25 ^@ Similarity ^@ Belongs to the CDV3 family. http://togogenome.org/gene/110368:LOC112044962 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/110368:LOC112048473 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Endosome membrane|||Golgi apparatus membrane|||Late endosome membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/110368:LOC112049160 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCH8 ^@ Function|||Similarity ^@ Belongs to the MINDY deubiquitinase family. FAM188 subfamily.|||Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. http://togogenome.org/gene/110368:LOC112057988 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9B4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer. http://togogenome.org/gene/110368:LOC112053585 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP43 family.|||cilium basal body http://togogenome.org/gene/110368:LOC112046556 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0456 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112050712 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNR1 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/110368:LOC112046767 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2F9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KISH family.|||Golgi apparatus membrane|||Involved in the early part of the secretory pathway.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112053023 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT74 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/110368:LOC112058093 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9Q9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/110368:LOC112049570 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFIIE beta subunit family.|||Nucleus|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|||Tetramer of two alpha and two beta chains. http://togogenome.org/gene/110368:LOC112051242 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKX9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112050776 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112056879 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDK2AP family.|||Nucleus http://togogenome.org/gene/110368:LOC112047972 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2F3 ^@ Similarity ^@ Belongs to the gamma-BBH/TMLD family. http://togogenome.org/gene/110368:LOC112054998 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S1 family.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/110368:LOC112052111 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047950 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OSTC family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/110368:LOC112044961 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQK1|||http://purl.uniprot.org/uniprot/A0A6J1MUW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/110368:LOC112058375 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAP2|||http://purl.uniprot.org/uniprot/A0A6J1PAP3|||http://purl.uniprot.org/uniprot/A0A6J1PAS8|||http://purl.uniprot.org/uniprot/A0A6J1PAV6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053353 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYJ6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112051700 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMT0 ^@ Similarity ^@ Belongs to the LAMTOR4 family. http://togogenome.org/gene/110368:LOC112048504 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112042889 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHM3|||http://purl.uniprot.org/uniprot/A0A6J1MLN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112048557 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/110368:LOC112047614 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6A6 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112055511 ^@ http://purl.uniprot.org/uniprot/A0A6J1P232 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.|||Belongs to the complex I NDUFV3 subunit family.|||Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme. http://togogenome.org/gene/110368:LOC112051516 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDX2|||http://purl.uniprot.org/uniprot/A0A6J1NGC4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/110368:LOC112048034 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7S1|||http://purl.uniprot.org/uniprot/A0A6J1NDJ9 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/110368:LOC112043635 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPU5 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112046333 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0P1 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/110368:LOC112052205 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGQ0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/110368:LOC112057779 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112051930 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTB0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048596 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAD3|||http://purl.uniprot.org/uniprot/A0A6J1NFW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044620 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTQ1 ^@ Function|||PTM|||Similarity ^@ Belongs to the eIF-5A family.|||Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/110368:LOC112050824 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic13 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112049983 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UQCRH/QCR6 family.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112052587 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKM6|||http://purl.uniprot.org/uniprot/A0A6J1NKN1|||http://purl.uniprot.org/uniprot/A0A6J1NRK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kinesin light chain family.|||Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.|||Oligomeric complex composed of two heavy chains and two light chains.|||cytoskeleton http://togogenome.org/gene/110368:LOC112046221 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/110368:LOC112049088 ^@ http://purl.uniprot.org/uniprot/A0A6J1N415 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053282 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNC6 ^@ Similarity ^@ Belongs to the cAMP-dependent kinase regulatory chain family. http://togogenome.org/gene/110368:LOC112043430 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHA4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051574 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane|||May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.|||Membrane|||Microsome membrane http://togogenome.org/gene/110368:LOC112046150 ^@ http://purl.uniprot.org/uniprot/A0A6J1N627 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Nucleus|||Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/110368:LOC112058293 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAA5 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. http://togogenome.org/gene/110368:LOC112053610 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044028 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY88 ^@ Function|||Similarity|||Subunit ^@ Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.|||Belongs to the snRNP Sm proteins family.|||Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30. http://togogenome.org/gene/110368:LOC112044074 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Belongs to the scoloptoxin-05 family.|||Membrane http://togogenome.org/gene/110368:LOC112043250 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJ15 ^@ Similarity ^@ Belongs to the exonuclease superfamily. TREX family. http://togogenome.org/gene/110368:LOC112052900 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWU7 ^@ Similarity ^@ Belongs to the U2 small nuclear ribonucleoprotein A family. http://togogenome.org/gene/110368:LOC112056517 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 6A family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112058546 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Endoplasmic reticulum membrane|||Membrane|||Necessary for protein translocation in the endoplasmic reticulum. http://togogenome.org/gene/110368:LOC112049781 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKB5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112052225 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ16 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/110368:LOC112050216 ^@ http://purl.uniprot.org/uniprot/A0A6J1N921 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM129 family.|||Membrane http://togogenome.org/gene/110368:LOC112043557 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPG0 ^@ Similarity ^@ Belongs to the nanos family. http://togogenome.org/gene/110368:LOC112057021 ^@ http://purl.uniprot.org/uniprot/A0A6J1P615|||http://purl.uniprot.org/uniprot/A0A6J1P621|||http://purl.uniprot.org/uniprot/A0A6J1P664 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation.|||Belongs to the AAA ATPase family. Spastin subfamily.|||Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules.|||Membrane|||centrosome|||cytoskeleton http://togogenome.org/gene/110368:LOC112058162 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9W8|||http://purl.uniprot.org/uniprot/A0A6J1P9X8|||http://purl.uniprot.org/uniprot/A0A6J1PAD4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/110368:LOC112050129 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112048695 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab GDI family.|||Cytoplasm|||Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. http://togogenome.org/gene/110368:LOC112053961 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/110368:LOC112049267 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4U1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112043637 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKH7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050657 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCW2 ^@ Similarity ^@ Belongs to the polysaccharide monooxygenase AA13 family. http://togogenome.org/gene/110368:LOC112055790 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112044767 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit K family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112048609 ^@ http://purl.uniprot.org/uniprot/A0A6J1N293 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046171 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZY5|||http://purl.uniprot.org/uniprot/A0A6J1N670 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Cytoplasm|||In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. http://togogenome.org/gene/110368:LOC112049273 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIA3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26 family.|||Heterodimer of 2 subunits, IMMPL1 and IMMPL2.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112052240 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGU6 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/110368:LOC112051375 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFL6 ^@ Similarity ^@ Belongs to the neurochondrin family. http://togogenome.org/gene/110368:LOC112053735 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW81 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/110368:LOC112050396 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9M6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112053957 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0C5 ^@ Similarity ^@ Belongs to the VHL family. http://togogenome.org/gene/110368:LOC112045025 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes medium subunit family.|||Cell membrane|||coated pit http://togogenome.org/gene/110368:LOC112045815 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTS4 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/110368:LOC112051871 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN52 ^@ Similarity ^@ Belongs to the FAM122 family. http://togogenome.org/gene/110368:LOC112043941 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRA4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112045880 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQU8|||http://purl.uniprot.org/uniprot/A0A6J1MYK1|||http://purl.uniprot.org/uniprot/A0A6J1MYW5|||http://purl.uniprot.org/uniprot/A0A6J1N518 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/110368:LOC112048171 ^@ http://purl.uniprot.org/uniprot/A0A6J1N398|||http://purl.uniprot.org/uniprot/A0A6J1N8D3 ^@ Function|||Similarity ^@ Belongs to the peptidase C12 family. BAP1 subfamily.|||Polycomb group (PcG) protein. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1). Does not deubiquitinate monoubiquitinated histone H2B. Required to maintain the transcriptionally repressive state of homeotic genes throughout development. The PR-DUB complex has weak or no activity toward 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. http://togogenome.org/gene/110368:LOC112054410 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQL3 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/110368:LOC112042844 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHH4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045875 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/110368:LOC112054436 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYY9 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/110368:LOC112053829 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQQ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057089 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6E1 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/110368:LOC112053823 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN50 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/110368:LOC112043043 ^@ http://purl.uniprot.org/uniprot/A0A6J1MG03|||http://purl.uniprot.org/uniprot/A0A6J1MUC1 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/110368:LOC112054303 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYG8 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/110368:LOC112043202 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VMA21 family.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. http://togogenome.org/gene/110368:LOC112046320 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSV9 ^@ Subcellular Location Annotation ^@ trans-Golgi network http://togogenome.org/gene/110368:LOC112045642 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ00 ^@ Similarity ^@ Belongs to the RRP7 family. http://togogenome.org/gene/110368:LOC112048026 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7Z1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112045674 ^@ http://purl.uniprot.org/uniprot/A0A6J1N498 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/110368:LOC112047257 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Z2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112046051 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ras family.|||Endosome membrane|||Membrane|||Recycling endosome membrane http://togogenome.org/gene/110368:LOC112054732 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUH2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/110368:LOC112050884 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ59 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/110368:LOC112048570 ^@ http://purl.uniprot.org/uniprot/A0A6J1N230 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ARTD/PARP family.|||Nucleus http://togogenome.org/gene/110368:LOC112046291 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0T0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COA3 family.|||Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.|||Membrane|||Required for assembly of cytochrome c oxidase (complex IV). http://togogenome.org/gene/110368:LOC112047942 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZM3|||http://purl.uniprot.org/uniprot/A0A6J1N2C2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/110368:LOC112047301 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZY1 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112044684 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SYS1 family.|||Golgi apparatus membrane|||Involved in protein trafficking.|||Membrane http://togogenome.org/gene/110368:LOC112045866 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTY9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045203 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2E4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049494 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8D0 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/110368:LOC112046309 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family.|||Secreted http://togogenome.org/gene/110368:LOC112044974 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMJ6 ^@ Similarity ^@ Belongs to the SZRD1 family. http://togogenome.org/gene/110368:LOC112051590 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGK6 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112051312 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL72 ^@ Similarity ^@ Belongs to the lin-52 family. http://togogenome.org/gene/110368:LOC112048472 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/110368:LOC112053704 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUX9 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/110368:LOC112047081 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYU3 ^@ Similarity ^@ Belongs to the EMC7 family. http://togogenome.org/gene/110368:LOC112058456 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBR8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112053932 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/110368:LOC112055179 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZW0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Homodimer.|||Peroxisome http://togogenome.org/gene/110368:LOC112047825 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6W1|||http://purl.uniprot.org/uniprot/A0A6J1N750 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M13 family.|||Cell membrane http://togogenome.org/gene/110368:LOC112043230 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046736 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXE3 ^@ Similarity ^@ Belongs to the CENP-X/MHF2 family. http://togogenome.org/gene/110368:LOC112048949 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/110368:LOC112043087 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112045447 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3C6 ^@ Similarity ^@ Belongs to the Toll-like receptor family. http://togogenome.org/gene/110368:LOC112056420 ^@ http://purl.uniprot.org/uniprot/A0A6J1P354 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/110368:LOC112058524 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBP2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112055301 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112052624 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVY8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112046202 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||Nucleus http://togogenome.org/gene/110368:LOC112051685 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH12|||http://purl.uniprot.org/uniprot/A0A6J1NMR0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043211 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMZ2 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/110368:LOC112043559 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT4 family.|||Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.|||Nucleus http://togogenome.org/gene/110368:LOC112043992 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLX6|||http://purl.uniprot.org/uniprot/A0A6J1MRH3|||http://purl.uniprot.org/uniprot/A0A6J1MY43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112051543 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE14 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/110368:LOC112058371 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB81 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/110368:LOC112051586 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE93 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112051763 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHA3|||http://purl.uniprot.org/uniprot/A0A6J1NN23 ^@ Similarity ^@ Belongs to the calcineurin regulatory subunit family. http://togogenome.org/gene/110368:LOC112056681 ^@ http://purl.uniprot.org/uniprot/A0A6J1P545 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053288 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYA2 ^@ Domain|||Function|||Similarity ^@ Belongs to the DEAD box helicase family.|||RNA helicase.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/110368:LOC112049568 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8R7 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112047369 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5G8 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/110368:LOC112055703 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1C2 ^@ Similarity ^@ Belongs to the WD repeat WDR91 family. http://togogenome.org/gene/110368:LOC112045218 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PCNA family.|||Nucleus|||This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. http://togogenome.org/gene/110368:LOC112044339 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSP3 ^@ Similarity ^@ Belongs to the WD repeat SEC13 family. http://togogenome.org/gene/110368:LOC112055291 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZW10 family.|||kinetochore http://togogenome.org/gene/110368:LOC112047437 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Component of the RNA polymerase III (Pol III) complex.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/110368:LOC112043222 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN10 ^@ Similarity ^@ Belongs to the exonuclease superfamily. TREX family. http://togogenome.org/gene/110368:LOC112051865 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Membrane http://togogenome.org/gene/110368:LOC112043135 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGA6 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/110368:LOC112048652 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2F2|||http://purl.uniprot.org/uniprot/A0A6J1NG38 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/110368:LOC112050499 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHS0 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/110368:LOC112042953 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||Nucleus http://togogenome.org/gene/110368:LOC112045883 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU15 ^@ Similarity ^@ Belongs to the SELO family. http://togogenome.org/gene/110368:LOC112043703 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. Probably involved in vesicular traffic. http://togogenome.org/gene/110368:LOC112051372 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDA8 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112054662 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/110368:LOC112058111 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9S6 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/110368:LOC112051228 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCP9 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/110368:LOC112047191 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HEXIM family.|||Nucleus http://togogenome.org/gene/110368:LOC112052625 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRP8 ^@ Similarity ^@ Belongs to the NECAP family. http://togogenome.org/gene/110368:LOC112044902 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMB0|||http://purl.uniprot.org/uniprot/A0A6J1MQD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112057777 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112051598 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Endosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112049719 ^@ http://purl.uniprot.org/uniprot/A0A6J1NET8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048368 ^@ http://purl.uniprot.org/uniprot/A0A6J1N421 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 5A family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112051575 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI7|||http://purl.uniprot.org/uniprot/A0A6J1NMA6 ^@ Function|||Similarity ^@ Belongs to the tRNA-intron endonuclease family.|||Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. http://togogenome.org/gene/110368:LOC112051696 ^@ http://purl.uniprot.org/uniprot/A0A6J1NML3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCRIP family.|||Nucleus|||Stress granule http://togogenome.org/gene/110368:LOC112054374 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1E3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/110368:LOC112051061 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGJ1|||http://purl.uniprot.org/uniprot/A0A6J1NEF8 ^@ Similarity ^@ Belongs to the teashirt C2H2-type zinc-finger protein family. http://togogenome.org/gene/110368:LOC112044006 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGG4 ^@ Similarity ^@ Belongs to the polysaccharide monooxygenase AA13 family. http://togogenome.org/gene/110368:LOC112047403 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5B7|||http://purl.uniprot.org/uniprot/A0A6J1N5L5 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/110368:LOC112048602 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAD8 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/110368:LOC112051406 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane http://togogenome.org/gene/110368:LOC112050646 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Cytoplasm|||Mitochondrion http://togogenome.org/gene/110368:LOC112047396 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nup35 family.|||Functions as a component of the nuclear pore complex (NPC).|||nuclear pore complex http://togogenome.org/gene/110368:LOC112043023 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI80 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112053836 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVG9 ^@ Function|||Similarity ^@ Belongs to the sarcoglycan alpha/epsilon family.|||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. http://togogenome.org/gene/110368:LOC112052495 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHZ6 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/110368:LOC112046176 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZZ3 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/110368:LOC112052344 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUW3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043999 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050550 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI46 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/110368:LOC112050433 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC39 ^@ Similarity ^@ Belongs to the DDI1 family. http://togogenome.org/gene/110368:LOC112057753 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8K8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112049706 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEQ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/110368:LOC112054501 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1M5 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112055125 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT75 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BABAM2 family.|||Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.|||Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.|||Cytoplasm|||May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.|||Nucleus http://togogenome.org/gene/110368:LOC112052139 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP66 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/110368:LOC112048172 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8K2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050078 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAP4|||http://purl.uniprot.org/uniprot/A0A6J1NG92 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. http://togogenome.org/gene/110368:LOC112057720 ^@ http://purl.uniprot.org/uniprot/A0A6J1P860 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112045915 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR00|||http://purl.uniprot.org/uniprot/A0A6J1MU58 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/110368:LOC112054520 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTN2 ^@ Similarity ^@ Belongs to the DDIT4 family. http://togogenome.org/gene/110368:LOC112047364 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXE9|||http://purl.uniprot.org/uniprot/A0A6J1N566|||http://purl.uniprot.org/uniprot/A0A6J1NB30 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/110368:LOC112057058 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6B9 ^@ Similarity ^@ Belongs to the COG2 family. http://togogenome.org/gene/110368:LOC112055170 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTE1 ^@ Function|||Similarity ^@ Belongs to the BRX1 family.|||Required for biogenesis of the 60S ribosomal subunit. http://togogenome.org/gene/110368:LOC112046844 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUS5 ^@ Similarity ^@ Belongs to the NXF family. http://togogenome.org/gene/110368:LOC112045874 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYV5 ^@ Subcellular Location Annotation ^@ P-body http://togogenome.org/gene/110368:LOC112055814 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2Q8 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/110368:LOC112054325 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYL9 ^@ Function|||Similarity ^@ Belongs to the WD repeat WDR48 family.|||Regulator of deubiquitinating complexes. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. http://togogenome.org/gene/110368:LOC112043925 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLP3|||http://purl.uniprot.org/uniprot/A0A6J1MR28|||http://purl.uniprot.org/uniprot/A0A6J1MR80|||http://purl.uniprot.org/uniprot/A0A6J1MXT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112046991 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3D1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051077 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEJ9|||http://purl.uniprot.org/uniprot/A0A6J1NEL3|||http://purl.uniprot.org/uniprot/A0A6J1NK10 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112051739 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMY8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/110368:LOC112045877 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYW0 ^@ Similarity ^@ Belongs to the APC15 family. http://togogenome.org/gene/110368:LOC112043936 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLS0|||http://purl.uniprot.org/uniprot/A0A6J1MRA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112045715 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXW6 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/110368:LOC112051582 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS43 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112046339 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSZ2|||http://purl.uniprot.org/uniprot/A0A6J1MW01|||http://purl.uniprot.org/uniprot/A0A6J1N0Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.|||Membrane http://togogenome.org/gene/110368:LOC112046250 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0B4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. http://togogenome.org/gene/110368:LOC112053824 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVF6|||http://purl.uniprot.org/uniprot/A0A6J1NZX0 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/110368:LOC112044452 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MESD family.|||Endoplasmic reticulum http://togogenome.org/gene/110368:LOC112050299 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH59 ^@ Similarity ^@ Belongs to the lin-9 family. http://togogenome.org/gene/110368:LOC112051287 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFB4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the spliceosome.|||Nucleus|||Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. http://togogenome.org/gene/110368:LOC112049841 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB3 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112044928 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMD8|||http://purl.uniprot.org/uniprot/A0A6J1MV18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043169 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIR4 ^@ Cofactor|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Divalent metal ions. Mg(2+) is the most effective. http://togogenome.org/gene/110368:LOC112043784 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQI2 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/110368:LOC112050767 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TLS1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112043212 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGJ6|||http://purl.uniprot.org/uniprot/A0A6J1MV03 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/110368:LOC112056025 ^@ http://purl.uniprot.org/uniprot/A0A6J1P469 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112044810 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLZ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112044748 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFC2 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112045290 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RAMP4 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112043104 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/110368:LOC112055287 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWK4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/110368:LOC112051175 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGH0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/110368:LOC112045307 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.|||Belongs to the wntless family.|||Endoplasmic reticulum membrane|||Endosome membrane|||Golgi apparatus membrane|||Interacts with wg; in the Golgi. Interacts with Vps35, a component of the retromer complex; wls stability is regulated by Vps35.|||Membrane|||Postsynaptic cell membrane|||Presynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112055821 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYU1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045252 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/110368:LOC112053941 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/110368:LOC112057784 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8C5|||http://purl.uniprot.org/uniprot/A0A6J1P8C6|||http://purl.uniprot.org/uniprot/A0A6J1P8H3|||http://purl.uniprot.org/uniprot/A0A6J1P8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112052769 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSB2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112054276 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPY8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112054803 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYU0 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/110368:LOC112042811 ^@ http://purl.uniprot.org/uniprot/A0A6J1MF91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex.|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112050933 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112048148 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/110368:LOC112055558 ^@ http://purl.uniprot.org/uniprot/A0A6J1P132 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/110368:LOC112054137 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112042993 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMH6 ^@ Similarity ^@ Belongs to the GTR/RAG GTP-binding protein family. http://togogenome.org/gene/110368:LOC112045556 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3S6 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112053510 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPA1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. http://togogenome.org/gene/110368:LOC112044240 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYX1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112048646 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/110368:LOC112050670 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. http://togogenome.org/gene/110368:LOC112049435 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043322 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGX3|||http://purl.uniprot.org/uniprot/A0A6J1MJA5|||http://purl.uniprot.org/uniprot/A0A6J1MNF2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/110368:LOC112049908 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA24 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112047934 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7C0|||http://purl.uniprot.org/uniprot/A0A6J1ND76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRIM/RBCC family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112043128 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUN0 ^@ Similarity ^@ Belongs to the RecA family. DMC1 subfamily. http://togogenome.org/gene/110368:LOC112052199 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Endoplasmic reticulum|||Membrane|||Mitochondrion membrane|||Nucleus http://togogenome.org/gene/110368:LOC112055888 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/110368:LOC112042959 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP18 family.|||Nucleus speckle http://togogenome.org/gene/110368:LOC112056026 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZM2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/110368:LOC112050650 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112055062 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZK2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112052189 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUB3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112052629 ^@ http://purl.uniprot.org/uniprot/A0A6J1NII2 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112043132 ^@ http://purl.uniprot.org/uniprot/A0A6J1MG97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/110368:LOC112046785 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2J9 ^@ Similarity ^@ Belongs to the BLCAP family. http://togogenome.org/gene/110368:LOC112043491 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHJ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Homodimer.|||Secreted http://togogenome.org/gene/110368:LOC112051646 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGS4 ^@ Similarity ^@ Belongs to the UBALD family. http://togogenome.org/gene/110368:LOC112049461 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049486 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ35 ^@ Similarity ^@ Belongs to the tropomyosin family. http://togogenome.org/gene/110368:LOC112044681 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPF6|||http://purl.uniprot.org/uniprot/A0A6J1MU01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112046296 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSR9|||http://purl.uniprot.org/uniprot/A0A6J1N6R3 ^@ Similarity ^@ Belongs to the RRM IMP/VICKZ family. http://togogenome.org/gene/110368:LOC112043673 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI13 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/110368:LOC112048712 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2M4 ^@ Function ^@ Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. http://togogenome.org/gene/110368:LOC112048258 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8T3 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/110368:LOC112044291 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 6 family.|||Nucleus http://togogenome.org/gene/110368:LOC112057117 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6E2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112050336 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SMU1 family.|||Nucleus speckle http://togogenome.org/gene/110368:LOC112052079 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG67 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112046414 ^@ http://purl.uniprot.org/uniprot/A0A6J1N163 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. http://togogenome.org/gene/110368:LOC112049365 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIL3 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/110368:LOC112050696 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAL8|||http://purl.uniprot.org/uniprot/A0A6J1ND16 ^@ Similarity ^@ Belongs to the pyrokinin family. http://togogenome.org/gene/110368:LOC112042803 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/110368:LOC112043476 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJU6|||http://purl.uniprot.org/uniprot/A0A6J1MP36 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/110368:LOC112047355 ^@ http://purl.uniprot.org/uniprot/A0A6J1N056|||http://purl.uniprot.org/uniprot/A0A6J1N551|||http://purl.uniprot.org/uniprot/A0A6J1N5D2|||http://purl.uniprot.org/uniprot/A0A6J1NB16 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/110368:LOC112046182 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044825 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ33 ^@ Similarity ^@ Belongs to the AAA ATPase family. PCH2 subfamily. http://togogenome.org/gene/110368:LOC112048404 ^@ http://purl.uniprot.org/uniprot/A0A6J1N476 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.|||Belongs to the VPS29 family.|||Endosome membrane http://togogenome.org/gene/110368:LOC112058498 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBA1|||http://purl.uniprot.org/uniprot/A0A6J1PBY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/110368:LOC112044972 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUY0|||http://purl.uniprot.org/uniprot/A0A6J1N1M8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily. http://togogenome.org/gene/110368:LOC112055413 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 18 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112053936 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNM2|||http://purl.uniprot.org/uniprot/A0A6J1P098 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043287 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGS6|||http://purl.uniprot.org/uniprot/A0A6J1MJ52|||http://purl.uniprot.org/uniprot/A0A6J1MV86 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit.|||Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. http://togogenome.org/gene/110368:LOC112046611 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054359 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/110368:LOC112058144 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9X2|||http://purl.uniprot.org/uniprot/A0A6J1PA71 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112046886 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUX6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053046 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase K family.|||Membrane http://togogenome.org/gene/110368:LOC112053796 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVC8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/110368:LOC112052241 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUH9 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/110368:LOC112047186 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/110368:LOC112047094 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYV6 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/110368:LOC112054869 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0A4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/110368:LOC112043983 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112045230 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVX7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112050460 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9T8 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/110368:LOC112053827 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/110368:LOC112048853 ^@ http://purl.uniprot.org/uniprot/A0A6J1N356 ^@ Similarity ^@ Belongs to the NIBP family. http://togogenome.org/gene/110368:LOC112048176 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8E5|||http://purl.uniprot.org/uniprot/A0A6J1N8M6|||http://purl.uniprot.org/uniprot/A0A6J1NE51 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049342 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane magnesium transporter (TC 1.A.67) family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport. http://togogenome.org/gene/110368:LOC112049619 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEB3 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112050068 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Belongs to the scoloptoxin-05 family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112046311 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0W0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053562 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PurH family.|||cytosol http://togogenome.org/gene/110368:LOC112058260 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/110368:LOC112047065 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.|||Nucleus http://togogenome.org/gene/110368:LOC112051165 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKC2|||http://purl.uniprot.org/uniprot/A0A6J1NKJ2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/110368:LOC112045987 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044807 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/110368:LOC112046851 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF12 family.|||Nucleus http://togogenome.org/gene/110368:LOC112053405 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYQ2 ^@ Similarity ^@ Belongs to the BLOC1S3 family. http://togogenome.org/gene/110368:LOC112046545 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7J9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048682 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAR1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050533 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055543 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043844 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQW0|||http://purl.uniprot.org/uniprot/A0A6J1MXG7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112048815 ^@ http://purl.uniprot.org/uniprot/A0A6J1N311 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL42 family. http://togogenome.org/gene/110368:LOC112046892 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY23 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/110368:LOC112052588 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPC2 family.|||Secreted http://togogenome.org/gene/110368:LOC112046537 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWM2|||http://purl.uniprot.org/uniprot/A0A6J1N1R5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044806 ^@ http://purl.uniprot.org/uniprot/A0A6J1N110 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 8 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112047324 ^@ http://purl.uniprot.org/uniprot/A0A6J1N013 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112053828 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWL5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045364 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRZ5 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/110368:LOC112042932 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHT6|||http://purl.uniprot.org/uniprot/A0A6J1MMA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112042791 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052196 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/110368:LOC112054484 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXQ3|||http://purl.uniprot.org/uniprot/A0A6J1P1L1 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/110368:LOC112050141 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/110368:LOC112053663 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMD2|||http://purl.uniprot.org/uniprot/A0A6J1NUR8 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/110368:LOC112045919 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU63|||http://purl.uniprot.org/uniprot/A0A6J1MZ11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050393 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHG7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/110368:LOC112048489 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFB1 ^@ Similarity ^@ Belongs to the LIMR family. http://togogenome.org/gene/110368:LOC112044998 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1Q8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112044627 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTS1 ^@ Similarity ^@ Belongs to the HTATSF1 family. http://togogenome.org/gene/110368:LOC112054011 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/110368:LOC112058170 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9Y6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/110368:LOC112056240 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3N1 ^@ Similarity ^@ Belongs to the selenoprotein M/F family. http://togogenome.org/gene/110368:LOC112046195 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0C9 ^@ Similarity ^@ Belongs to the DENR family. http://togogenome.org/gene/110368:LOC112052663 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/110368:LOC112047555 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112043471 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVZ1 ^@ Similarity ^@ Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/110368:LOC112053958 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVZ0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. Sedlin subfamily.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network|||perinuclear region http://togogenome.org/gene/110368:LOC112052368 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV17|||http://purl.uniprot.org/uniprot/A0A6J1NV91 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/110368:LOC112051775 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN41 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/110368:LOC112047252 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055384 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/110368:LOC112043640 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKI2 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/110368:LOC112057166 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6J5|||http://purl.uniprot.org/uniprot/A0A6J1P6M3|||http://purl.uniprot.org/uniprot/A0A6J1P6M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.|||nucleolus http://togogenome.org/gene/110368:LOC112053414 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUY0 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112058600 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMCO4 family.|||Membrane http://togogenome.org/gene/110368:LOC112046877 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3B4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112047442 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5F8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/110368:LOC112048243 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8R0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047561 ^@ http://purl.uniprot.org/uniprot/A0A6J1N643 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/110368:LOC112048707 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2L5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/110368:LOC112043588 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHU4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112056849 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112044809 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Nucleus http://togogenome.org/gene/110368:LOC112044751 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPQ8|||http://purl.uniprot.org/uniprot/A0A6J1MUA6 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/110368:LOC112044568 ^@ http://purl.uniprot.org/uniprot/A0A6J1N039 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112043875 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eS21 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/110368:LOC112058408 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAU4 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/110368:LOC112043034 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AGK family.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/110368:LOC112043508 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPE8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112044959 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQJ8 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/110368:LOC112044278 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/110368:LOC112051958 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI03 ^@ Subcellular Location Annotation ^@ Cytoplasmic vesicle|||Vesicle http://togogenome.org/gene/110368:LOC112050539 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA34 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. http://togogenome.org/gene/110368:LOC112056186 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXK7 ^@ Function|||Similarity ^@ Belongs to the tRNA-intron endonuclease family.|||Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. http://togogenome.org/gene/110368:LOC112058471 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB50|||http://purl.uniprot.org/uniprot/A0A6J1PB90 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/110368:LOC112056277 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3Q2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. http://togogenome.org/gene/110368:LOC112058003 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9B1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043822 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIJ7 ^@ Similarity ^@ Belongs to the DPH3 family. http://togogenome.org/gene/110368:LOC112052143 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPP9 ^@ Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/110368:LOC112058503 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBZ5 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112054031 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRM4 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/110368:LOC112050392 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9L4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112055086 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT09|||http://purl.uniprot.org/uniprot/A0A6J1NVW5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058263 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA99 ^@ Similarity ^@ Belongs to the DOCK family. http://togogenome.org/gene/110368:LOC112051090 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK74 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/110368:LOC112053219 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU44 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/110368:LOC112053371 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL91|||http://purl.uniprot.org/uniprot/A0A6J1NTQ8|||http://purl.uniprot.org/uniprot/A0A6J1NYM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.|||Membrane|||Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055501 ^@ http://purl.uniprot.org/uniprot/A0A6J1P218 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIPK family.|||Secreted http://togogenome.org/gene/110368:LOC112058377 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAP6|||http://purl.uniprot.org/uniprot/A0A6J1PAQ1|||http://purl.uniprot.org/uniprot/A0A6J1PAT3|||http://purl.uniprot.org/uniprot/A0A6J1PAV9|||http://purl.uniprot.org/uniprot/A0A6J1PB95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112058096 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA12 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/110368:LOC112043377 ^@ http://purl.uniprot.org/uniprot/A0A6J1MH47|||http://purl.uniprot.org/uniprot/A0A6J1MH50|||http://purl.uniprot.org/uniprot/A0A6J1MJI2|||http://purl.uniprot.org/uniprot/A0A6J1MJI7|||http://purl.uniprot.org/uniprot/A0A6J1MNP3|||http://purl.uniprot.org/uniprot/A0A6J1MNP8|||http://purl.uniprot.org/uniprot/A0A6J1MNT5|||http://purl.uniprot.org/uniprot/A0A6J1MNU0|||http://purl.uniprot.org/uniprot/A0A6J1MVM3|||http://purl.uniprot.org/uniprot/A0A6J1MVM5|||http://purl.uniprot.org/uniprot/A0A6J1MVM9 ^@ Similarity ^@ Belongs to the PICALM/SNAP91 family. http://togogenome.org/gene/110368:LOC112045395 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS25 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112057676 ^@ http://purl.uniprot.org/uniprot/A0A6J1P835 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/110368:LOC112049722 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Integrator subunit 10 family.|||Nucleus http://togogenome.org/gene/110368:LOC112045583 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXL8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/110368:LOC112049422 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/110368:LOC112051617 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEC6 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112051331 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112052208 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPG4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043769 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQC3 ^@ Similarity ^@ Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily. http://togogenome.org/gene/110368:LOC112044705 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0M1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112056631 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4W4 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/110368:LOC112053756 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/110368:LOC112045029 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1U9 ^@ Similarity ^@ In the C-terminal section; belongs to the GART family.|||In the N-terminal section; belongs to the GARS family.|||In the central section; belongs to the AIR synthase family. http://togogenome.org/gene/110368:LOC112044009 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLZ8|||http://purl.uniprot.org/uniprot/A0A6J1MRJ4|||http://purl.uniprot.org/uniprot/A0A6J1MY62 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/110368:LOC112050898 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDT3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/110368:LOC112052093 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP13 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/110368:LOC112045036 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV64 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/110368:LOC112043539 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the geminin family.|||Nucleus http://togogenome.org/gene/110368:LOC112055364 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0F9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family. http://togogenome.org/gene/110368:LOC112045331 ^@ http://purl.uniprot.org/uniprot/A0A0B5L5W1 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/110368:LOC112051501 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Necessary for the splicing of pre-mRNA.|||Nucleus http://togogenome.org/gene/110368:LOC112049044 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6P7 ^@ Similarity ^@ Belongs to the proteasome subunit S14 family. http://togogenome.org/gene/110368:LOC112044523 ^@ http://purl.uniprot.org/uniprot/A0A6J1N004 ^@ Similarity ^@ Belongs to the VPS13 family. http://togogenome.org/gene/110368:LOC112051388 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFN4 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/110368:LOC112044357 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSQ4 ^@ Similarity ^@ Belongs to the WD repeat DCAF10 family. http://togogenome.org/gene/110368:LOC112053316 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYF9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049572 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0220 family.|||Membrane http://togogenome.org/gene/110368:LOC112043749 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/110368:LOC112043995 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRH7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112050890 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112045239 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRJ6|||http://purl.uniprot.org/uniprot/A0A6J1MW65 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/110368:LOC112043812 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQJ6 ^@ Function|||Similarity ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB1 subunit family. http://togogenome.org/gene/110368:LOC112053409 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNV3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/110368:LOC112046626 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC42SE/SPEC family.|||Cell membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/110368:LOC112046763 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXH7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/110368:LOC112052547 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI61|||http://purl.uniprot.org/uniprot/A0A6J1NKH4|||http://purl.uniprot.org/uniprot/A0A6J1NRE1|||http://purl.uniprot.org/uniprot/A0A6J1NVM6 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.|||cytoskeleton|||perinuclear region|||synaptosome http://togogenome.org/gene/110368:LOC112051116 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEP4 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/110368:LOC112047279 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4V5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.|||Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.|||Mitochondrion http://togogenome.org/gene/110368:LOC112054530 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXV9 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/110368:LOC112051220 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044215 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112048257 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the round spermatid basic protein 1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112053877 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX13 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/110368:LOC112044772 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLU4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/110368:LOC112058629 ^@ http://purl.uniprot.org/uniprot/A0A6J1PC19 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112053748 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV58 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112053188 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT19|||http://purl.uniprot.org/uniprot/A0A6J1NTZ5 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/110368:LOC112047669 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYI0|||http://purl.uniprot.org/uniprot/A0A6J1N196 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/110368:LOC112046535 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTJ7|||http://purl.uniprot.org/uniprot/A0A6J1N7J3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/110368:LOC112056457 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.|||Cytoplasm http://togogenome.org/gene/110368:LOC112043647 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWP2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family.|||Endoplasmic reticulum|||Part of the multisubunit transport protein particle (TRAPP) complex.|||cis-Golgi network http://togogenome.org/gene/110368:LOC112057654 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7S3|||http://purl.uniprot.org/uniprot/A0A6J1P7T1|||http://purl.uniprot.org/uniprot/A0A6J1P7T3|||http://purl.uniprot.org/uniprot/A0A6J1P7T5|||http://purl.uniprot.org/uniprot/A0A6J1P7T6|||http://purl.uniprot.org/uniprot/A0A6J1P7T9|||http://purl.uniprot.org/uniprot/A0A6J1P7U0|||http://purl.uniprot.org/uniprot/A0A6J1P7U4|||http://purl.uniprot.org/uniprot/A0A6J1P7U6|||http://purl.uniprot.org/uniprot/A0A6J1P7U7|||http://purl.uniprot.org/uniprot/A0A6J1P7U8|||http://purl.uniprot.org/uniprot/A0A6J1P7V1|||http://purl.uniprot.org/uniprot/A0A6J1P7V4|||http://purl.uniprot.org/uniprot/A0A6J1P7V8|||http://purl.uniprot.org/uniprot/A0A6J1P7W2|||http://purl.uniprot.org/uniprot/A0A6J1P7X4|||http://purl.uniprot.org/uniprot/A0A6J1P7Y7|||http://purl.uniprot.org/uniprot/A0A6J1P7Z2|||http://purl.uniprot.org/uniprot/A0A6J1P7Z6|||http://purl.uniprot.org/uniprot/A0A6J1P800|||http://purl.uniprot.org/uniprot/A0A6J1P825|||http://purl.uniprot.org/uniprot/A0A6J1P838|||http://purl.uniprot.org/uniprot/A0A6J1P850|||http://purl.uniprot.org/uniprot/A0A6J1P852|||http://purl.uniprot.org/uniprot/A0A6J1P857|||http://purl.uniprot.org/uniprot/A0A6J1P865 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/110368:LOC112053283 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY98 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin-like FAM58 subfamily. http://togogenome.org/gene/110368:LOC112052270 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Nucleus http://togogenome.org/gene/110368:LOC112047848 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/110368:LOC112046130 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV25 ^@ Similarity ^@ Belongs to the mitochondrion-specific ribosomal protein mS38 family. http://togogenome.org/gene/110368:LOC112052451 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK49 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS19 family. http://togogenome.org/gene/110368:LOC112047486 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXT4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046000 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF4 family.|||Nucleus http://togogenome.org/gene/110368:LOC112047017 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVN2|||http://purl.uniprot.org/uniprot/A0A6J1MYL4|||http://purl.uniprot.org/uniprot/A0A6J1N3Y1|||http://purl.uniprot.org/uniprot/A0A6J1N9H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/110368:LOC112047543 ^@ http://purl.uniprot.org/uniprot/A0A6J1N620 ^@ Similarity ^@ Belongs to the NPC2 family. http://togogenome.org/gene/110368:LOC112051690 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMR5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057822 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051978 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112045861 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Y7 ^@ Similarity ^@ Belongs to the TMEM9 family. http://togogenome.org/gene/110368:LOC112051562 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCR10/QCR9 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112058562 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/110368:LOC112052933 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS35 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112049612 ^@ http://purl.uniprot.org/uniprot/A0A6J1NED6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112051064 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEF2|||http://purl.uniprot.org/uniprot/A0A6J1NJX2|||http://purl.uniprot.org/uniprot/A0A6J1NK36|||http://purl.uniprot.org/uniprot/A0A6J1NQ14 ^@ Similarity ^@ Belongs to the glutaminase family. http://togogenome.org/gene/110368:LOC112050791 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112043379 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/110368:LOC112046251 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112053879 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWW6 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/110368:LOC112045324 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNV4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112054228 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.|||Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.|||Mitochondrion http://togogenome.org/gene/110368:LOC112045254 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRL3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045096 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/110368:LOC112044717 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU53 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058331 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB17 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112055545 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3M8 ^@ Function|||Similarity ^@ Belongs to the type IB topoisomerase family.|||Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/110368:LOC112052704 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIT3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-2B subfamily. http://togogenome.org/gene/110368:LOC112048344 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9C8 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112055254 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112048163 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8B7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/110368:LOC112053820 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Membrane http://togogenome.org/gene/110368:LOC112046357 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 23 family.|||Nucleus http://togogenome.org/gene/110368:LOC112048082 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2W3 ^@ Subcellular Location Annotation ^@ cilium basal body http://togogenome.org/gene/110368:LOC112046199 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112053797 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.|||Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type and beta-type subunits), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).|||Belongs to the adaptor complexes large subunit family.|||coated pit http://togogenome.org/gene/110368:LOC112051951 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTE3 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/110368:LOC112047229 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/110368:LOC112055854 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZ06 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/110368:LOC112049200 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCM1 ^@ Similarity ^@ Belongs to the API5 family. http://togogenome.org/gene/110368:LOC112047390 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXI5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/110368:LOC112045502 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX72 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/110368:LOC112046122 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS09|||http://purl.uniprot.org/uniprot/A0A6J1MZZ9|||http://purl.uniprot.org/uniprot/A0A6J1N022|||http://purl.uniprot.org/uniprot/A0A6J1N5Z2 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/110368:LOC112044075 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJH2|||http://purl.uniprot.org/uniprot/A0A6J1MM67|||http://purl.uniprot.org/uniprot/A0A6J1MRQ9 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/110368:LOC112043904 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Rab3-GAP regulatory subunit family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112046370 ^@ http://purl.uniprot.org/uniprot/A0A6J1N148 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044305 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK67 ^@ Similarity ^@ Belongs to the RAPGEF2 family. http://togogenome.org/gene/110368:LOC112056036 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWZ8|||http://purl.uniprot.org/uniprot/A0A6J1P473 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/110368:LOC112051278 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKU4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/110368:LOC112045354 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNZ0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/110368:LOC112044482 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TM2 family.|||Membrane http://togogenome.org/gene/110368:LOC112049474 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112053852 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNA5 ^@ Similarity ^@ Belongs to the TIM16/PAM16 family. http://togogenome.org/gene/110368:LOC112048889 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3A6|||http://purl.uniprot.org/uniprot/A0A6J1N671|||http://purl.uniprot.org/uniprot/A0A6J1N676|||http://purl.uniprot.org/uniprot/A0A6J1NH01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112046779 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112052076 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 1 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/110368:LOC112044285 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK43|||http://purl.uniprot.org/uniprot/A0A6J1MMX0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/110368:LOC112048015 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047763 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCJ3 ^@ Similarity ^@ Belongs to the AAR2 family. http://togogenome.org/gene/110368:LOC112053848 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVJ2 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/110368:LOC112045393 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWK9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112047264 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAP5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Golgi apparatus|||Lysosome|||Mitochondrion http://togogenome.org/gene/110368:LOC112043175 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUV7 ^@ Similarity ^@ Belongs to the CIMIP2 family. http://togogenome.org/gene/110368:LOC112053495 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV92 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/110368:LOC112043957 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJ36|||http://purl.uniprot.org/uniprot/A0A6J1MXZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112053376 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL96 ^@ Similarity ^@ Belongs to the apyrase family. http://togogenome.org/gene/110368:LOC112051258 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKZ3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL19 family. http://togogenome.org/gene/110368:LOC112046868 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXY4 ^@ Similarity ^@ Belongs to the hcp beta-lactamase family. http://togogenome.org/gene/110368:LOC112044081 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRR9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS26 family. http://togogenome.org/gene/110368:LOC112055417 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1T2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112053198 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKL1|||http://purl.uniprot.org/uniprot/A0A6J1NT32|||http://purl.uniprot.org/uniprot/A0A6J1NU09|||http://purl.uniprot.org/uniprot/A0A6J1NXW6 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/110368:LOC112047892 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZD8|||http://purl.uniprot.org/uniprot/A0A6J1N760|||http://purl.uniprot.org/uniprot/A0A6J1N763 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/110368:LOC112051914 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM138 family.|||Membrane|||Required for ciliogenesis.|||Vacuole membrane http://togogenome.org/gene/110368:LOC112044869 ^@ http://purl.uniprot.org/uniprot/A0A6J1N190 ^@ Similarity ^@ Belongs to the FAM10 family. http://togogenome.org/gene/110368:LOC112058588 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SWD2 family.|||Nucleus http://togogenome.org/gene/110368:LOC112052776 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRK6|||http://purl.uniprot.org/uniprot/A0A6J1NWG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/110368:LOC112053201 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU14 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/110368:LOC112051601 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGL9 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/110368:LOC112048469 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4F3|||http://purl.uniprot.org/uniprot/A0A6J1N9M0|||http://purl.uniprot.org/uniprot/A0A6J1N9U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HIBADH-related family. NP60 subfamily.|||Chromosome http://togogenome.org/gene/110368:LOC112051822 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNA7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/110368:LOC112047909 ^@ http://purl.uniprot.org/uniprot/A0A6J1N273 ^@ Function ^@ Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. http://togogenome.org/gene/110368:LOC112050591 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112051819 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSW5 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/110368:LOC112051483 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLQ0|||http://purl.uniprot.org/uniprot/A0A6J1NLW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112052584 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112051307 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL60 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/110368:LOC112046894 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8X1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051399 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDG1 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/110368:LOC112047374 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB85 ^@ Similarity ^@ Belongs to the ODR-4 family. http://togogenome.org/gene/110368:LOC112048898 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3D6|||http://purl.uniprot.org/uniprot/A0A6J1NBF6|||http://purl.uniprot.org/uniprot/A0A6J1NH32 ^@ Similarity ^@ Belongs to the SPSB family. http://togogenome.org/gene/110368:LOC112046855 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.|||Membrane http://togogenome.org/gene/110368:LOC112044036 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY99 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/110368:LOC112042794 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHC5 ^@ Function|||Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.|||E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress. http://togogenome.org/gene/110368:LOC112047679 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6D2|||http://purl.uniprot.org/uniprot/A0A6J1N6K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/110368:LOC112044805 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLY9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050981 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE42 ^@ Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. http://togogenome.org/gene/110368:LOC112048576 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112045589 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Catalyzes the transfer of galactose onto proteins or lipids.|||Membrane http://togogenome.org/gene/110368:LOC112053681 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUU0 ^@ Similarity ^@ Belongs to the WD repeat EBI family. http://togogenome.org/gene/110368:LOC112058320 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAD0 ^@ Function|||Similarity ^@ Belongs to the calponin family.|||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. http://togogenome.org/gene/110368:LOC112055806 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Nucleus|||Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/110368:LOC112051159 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKB2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112045199 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat peroxin-7 family.|||Peroxisome matrix|||cytosol http://togogenome.org/gene/110368:LOC112049925 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7P3|||http://purl.uniprot.org/uniprot/A0A6J1NKU8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112049647 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6F5 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. GMF subfamily. http://togogenome.org/gene/110368:LOC112046412 ^@ http://purl.uniprot.org/uniprot/A0A6J1N714 ^@ Similarity ^@ Belongs to the strictosidine synthase family. http://togogenome.org/gene/110368:LOC112046700 ^@ http://purl.uniprot.org/uniprot/A0A6J1N840 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/110368:LOC112050003 ^@ http://purl.uniprot.org/uniprot/A0A6J1N837 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112054250 ^@ http://purl.uniprot.org/uniprot/A0A6J1P140 ^@ Similarity ^@ Belongs to the selenium-binding protein family. http://togogenome.org/gene/110368:LOC112043582 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/110368:LOC112052931 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS31 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112053937 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVW6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/110368:LOC112052203 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPF9 ^@ Similarity ^@ Belongs to the peptidase C78 family. http://togogenome.org/gene/110368:LOC112058569 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBI5|||http://purl.uniprot.org/uniprot/A0A6J1PC76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase CarF family.|||Membrane http://togogenome.org/gene/110368:LOC112044236 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112051250 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the syndecan proteoglycan family.|||Cell surface proteoglycan.|||Membrane http://togogenome.org/gene/110368:LOC112045033 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV60 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112049961 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFR8 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/110368:LOC112058628 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBP6 ^@ Similarity ^@ Belongs to the peroxin-19 family. http://togogenome.org/gene/110368:LOC112057364 ^@ http://purl.uniprot.org/uniprot/A0A6J1P783 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112054738 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYN8|||http://purl.uniprot.org/uniprot/A0A6J1NZV0 ^@ Similarity ^@ Belongs to the nucleoplasmin family. http://togogenome.org/gene/110368:LOC112053010 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX75 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/110368:LOC112043914 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112051201 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQL1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/110368:LOC112057819 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112046722 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUC6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/110368:LOC112052246 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Su(H) family.|||Nucleus http://togogenome.org/gene/110368:LOC112054781 ^@ http://purl.uniprot.org/uniprot/A0A6J1P268 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112053622 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUM7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PDE6D/unc-119 family.|||Cytoplasm|||Interacts with Pde6.|||Nucleus http://togogenome.org/gene/110368:LOC112053505 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVA8 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/110368:LOC112055839 ^@ http://purl.uniprot.org/uniprot/A0A6J1P420 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/110368:LOC112052726 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.|||nucleoplasm http://togogenome.org/gene/110368:LOC112050881 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBA9 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/110368:LOC112042896 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFH3 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/110368:LOC112048837 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBA7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044824 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUL8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/110368:LOC112044621 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTL8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/110368:LOC112049073 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047487 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBH8 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/110368:LOC112043486 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHI2|||http://purl.uniprot.org/uniprot/A0A6J1MJY0|||http://purl.uniprot.org/uniprot/A0A6J1MJY6|||http://purl.uniprot.org/uniprot/A0A6J1MP80|||http://purl.uniprot.org/uniprot/A0A6J1MP94|||http://purl.uniprot.org/uniprot/A0A6J1MPA9|||http://purl.uniprot.org/uniprot/A0A6J1MW32|||http://purl.uniprot.org/uniprot/A0A6J1MW38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050802 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP16 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112052346 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NPY family.|||Secreted http://togogenome.org/gene/110368:LOC112044713 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat striatin family.|||Membrane http://togogenome.org/gene/110368:LOC112045361 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNZ9 ^@ Function|||Similarity ^@ Belongs to the R-transferase family.|||Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. http://togogenome.org/gene/110368:LOC112048309 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3U8 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/110368:LOC112050899 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBD0 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/110368:LOC112045201 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/110368:LOC112055285 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/110368:LOC112051921 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112052885 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJH4|||http://purl.uniprot.org/uniprot/A0A6J1NLU5|||http://purl.uniprot.org/uniprot/A0A6J1NSS6|||http://purl.uniprot.org/uniprot/A0A6J1NWW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112047541 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tim44 family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112051536 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS7 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/110368:LOC112055538 ^@ http://purl.uniprot.org/uniprot/A0A6J1P113 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/110368:LOC112046029 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRH1|||http://purl.uniprot.org/uniprot/A0A6J1MZB8 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/110368:LOC112057763 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053698 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMJ2 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/110368:LOC112043554 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047299 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAU5 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112047336 ^@ http://purl.uniprot.org/uniprot/A0A6J1N035 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase gamma chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. http://togogenome.org/gene/110368:LOC112043718 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI60|||http://purl.uniprot.org/uniprot/A0A6J1MKT0 ^@ Similarity ^@ Belongs to the major royal jelly protein family. http://togogenome.org/gene/110368:LOC112054138 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the otopetrin family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112053292 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYA8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047761 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1L9 ^@ Similarity ^@ Belongs to the CSN12 family. http://togogenome.org/gene/110368:LOC112049358 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND97 ^@ Function|||Similarity ^@ Belongs to the APC13 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. http://togogenome.org/gene/110368:LOC112043735 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGN8 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112053230 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044102 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMA7 ^@ Similarity ^@ Belongs to the methylthiotransferase family. MiaB subfamily. http://togogenome.org/gene/110368:LOC112058539 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBE6 ^@ Similarity ^@ Belongs to the CWC15 family. http://togogenome.org/gene/110368:LOC112055487 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUL0|||http://purl.uniprot.org/uniprot/A0A6J1P205 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/110368:LOC112055813 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1K6|||http://purl.uniprot.org/uniprot/A0A6J1P3Z7 ^@ Similarity|||Subunit ^@ Belongs to the importin beta family.|||Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6. http://togogenome.org/gene/110368:LOC112048614 ^@ http://purl.uniprot.org/uniprot/A0A6J1N299|||http://purl.uniprot.org/uniprot/A0A6J1NFY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/110368:LOC112046072 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRR8|||http://purl.uniprot.org/uniprot/A0A6J1N5R9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051836 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF74 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/110368:LOC112043967 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJ49 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112045330 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Membrane http://togogenome.org/gene/110368:LOC112047297 ^@ http://purl.uniprot.org/uniprot/I6LEN1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112057674 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/110368:LOC112056147 ^@ http://purl.uniprot.org/uniprot/A0A6J1P006 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/110368:LOC112048541 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9Y5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/110368:LOC112046481 ^@ http://purl.uniprot.org/uniprot/A0A6J1N147 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/110368:LOC112046961 ^@ http://purl.uniprot.org/uniprot/A0A6J1N971 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112050085 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112050441 ^@ http://purl.uniprot.org/uniprot/A0A0N9DUU8 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/110368:LOC112049973 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane http://togogenome.org/gene/110368:LOC112047713 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/110368:LOC112045437 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3C1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043226 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGL2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112055220 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/110368:LOC112050262 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH03|||http://purl.uniprot.org/uniprot/A0A6J1NH19 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. http://togogenome.org/gene/110368:LOC112056740 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5B9 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/110368:LOC112054396 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052572 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQR6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048360 ^@ http://purl.uniprot.org/uniprot/A0A6J1N965 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112045902 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU40 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/110368:LOC112046878 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXZ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112054263 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWW3 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/110368:LOC112042986 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm http://togogenome.org/gene/110368:LOC112053680 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMF6|||http://purl.uniprot.org/uniprot/A0A6J1NQ08 ^@ Similarity ^@ Belongs to the SH3RF family. http://togogenome.org/gene/110368:LOC112049795 ^@ http://purl.uniprot.org/uniprot/A0A6J1N775 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Golgi pH regulator (TC 1.A.38) family.|||Membrane http://togogenome.org/gene/110368:LOC112044461 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNI6 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/110368:LOC112044639 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/110368:LOC112051697 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH25 ^@ Similarity ^@ Belongs to the CCZ1 family. http://togogenome.org/gene/110368:LOC112045371 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS06 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049147 ^@ http://purl.uniprot.org/uniprot/A0A6J1N773 ^@ Similarity ^@ Belongs to the IFT57 family. http://togogenome.org/gene/110368:LOC112056086 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112044002 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJ91 ^@ Similarity ^@ Belongs to the NAC-beta family. http://togogenome.org/gene/110368:LOC112048574 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/110368:LOC112047236 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Lysosome membrane http://togogenome.org/gene/110368:LOC112047920 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043890 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/110368:LOC112046041 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5M4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS10 family. http://togogenome.org/gene/110368:LOC112046882 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY04 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048956 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3H8|||http://purl.uniprot.org/uniprot/A0A6J1NBL7 ^@ Similarity ^@ Belongs to the MIX23 family. http://togogenome.org/gene/110368:LOC112045859 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTX9 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/110368:LOC112050152 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055280 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWJ3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/110368:LOC112047397 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0A9 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112044453 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNH0|||http://purl.uniprot.org/uniprot/A0A6J1MT24|||http://purl.uniprot.org/uniprot/A0A6J1MZQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.|||Membrane http://togogenome.org/gene/110368:LOC112050435 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG13 family. Metazoan subfamily.|||Preautophagosomal structure http://togogenome.org/gene/110368:LOC112049202 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7C8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112058589 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBL1 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/110368:LOC112058501 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBA5|||http://purl.uniprot.org/uniprot/A0A6J1PBA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/110368:LOC112047491 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0L1 ^@ Subcellular Location Annotation|||Subunit ^@ Heterodimer of burs and pburs.|||Secreted http://togogenome.org/gene/110368:LOC112056617 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4U4 ^@ Similarity ^@ Belongs to the CDI family. http://togogenome.org/gene/110368:LOC112048130 ^@ http://purl.uniprot.org/uniprot/A0A6J1N329 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047377 ^@ http://purl.uniprot.org/uniprot/A0A6J1N587|||http://purl.uniprot.org/uniprot/A0A6J1NB50 ^@ Similarity ^@ Belongs to the biotin--protein ligase family. http://togogenome.org/gene/110368:LOC112043417 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNZ2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051098 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK85 ^@ Cofactor|||Function|||Similarity ^@ Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.|||Belongs to the tRNA(His) guanylyltransferase family.|||Binds 2 magnesium ions per subunit. http://togogenome.org/gene/110368:LOC112052030 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112054269 ^@ http://purl.uniprot.org/uniprot/A0A6J1P151 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112042924 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLT1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112058530 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/110368:LOC112053194 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXW1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112052903 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/110368:LOC112045225 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW49 ^@ Similarity ^@ Belongs to the COX20 family. http://togogenome.org/gene/110368:LOC112045120 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044422 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLL4 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/110368:LOC112058056 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9I1 ^@ Similarity ^@ Belongs to the peptidase M50A family. http://togogenome.org/gene/110368:LOC112052276 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112043333 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/110368:LOC112047717 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1G3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054345 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA12 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112048413 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.|||Mitochondrion http://togogenome.org/gene/110368:LOC112058378 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAQ7|||http://purl.uniprot.org/uniprot/A0A6J1PAW4 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 38 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/110368:LOC112053203 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT39|||http://purl.uniprot.org/uniprot/A0A6J1NXX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Golgi apparatus|||clathrin-coated pit http://togogenome.org/gene/110368:LOC112048512 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9S0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/110368:LOC112053560 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM17 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112052223 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050846 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDI7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/110368:LOC112048229 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8W8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT6 family.|||Nucleus|||Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). http://togogenome.org/gene/110368:LOC112058330 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAH2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043157 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIP9 ^@ Similarity ^@ Belongs to the strumpellin family. http://togogenome.org/gene/110368:LOC112054104 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112048622 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2B1 ^@ Function ^@ Nuclease that cleaves 2',3'-cGAMP. http://togogenome.org/gene/110368:LOC112046742 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PHAX family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112046298 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6S2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL20 family. http://togogenome.org/gene/110368:LOC112048433 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4B3|||http://purl.uniprot.org/uniprot/A0A6J1N9P9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24 family. SPT16 subfamily.|||Chromosome|||Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.|||Component of the FACT complex.|||Nucleus http://togogenome.org/gene/110368:LOC112056836 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/110368:LOC112046734 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2R7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS5 subunit family.|||Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112043220 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNB4 ^@ Similarity ^@ Belongs to the NFX1 family. http://togogenome.org/gene/110368:LOC112045184 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRD0|||http://purl.uniprot.org/uniprot/A0A6J1MVR7|||http://purl.uniprot.org/uniprot/A0A6J1MVZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0359 family.|||Membrane http://togogenome.org/gene/110368:LOC112047224 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWN1|||http://purl.uniprot.org/uniprot/A0A6J1MZK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112049830 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9R1|||http://purl.uniprot.org/uniprot/A0A6J1NF91 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/110368:LOC112052150 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGH9|||http://purl.uniprot.org/uniprot/A0A6J1NIX9|||http://purl.uniprot.org/uniprot/A0A6J1NPQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112042808 ^@ http://purl.uniprot.org/uniprot/A0A6J1MF82 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/110368:LOC112049783 ^@ http://purl.uniprot.org/uniprot/A0A6J1N761|||http://purl.uniprot.org/uniprot/A0A6J1NF28 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/110368:LOC112054541 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR00 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Homodimer.|||Mitochondrion|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. http://togogenome.org/gene/110368:LOC112050769 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNW9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047412 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMCO1 family.|||Calcium-selective channel required to prevent calcium stores from overfilling.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112046714 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXA9|||http://purl.uniprot.org/uniprot/A0A6J1N289|||http://purl.uniprot.org/uniprot/A0A6J1N2N6|||http://purl.uniprot.org/uniprot/A0A6J1N874 ^@ Similarity ^@ Belongs to the MAPRE family. http://togogenome.org/gene/110368:LOC112049991 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFV4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112046510 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/110368:LOC112052160 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI8 ^@ Caution|||Subcellular Location Annotation ^@ Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112047656 ^@ http://purl.uniprot.org/uniprot/A0A6J1N694 ^@ Cofactor|||Similarity ^@ Belongs to the transglutaminase superfamily. Transglutaminase family.|||Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/110368:LOC112046050 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZM7 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/110368:LOC112052239 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJB1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/110368:LOC112046185 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/110368:LOC112049519 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048166 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8C3 ^@ Similarity ^@ Belongs to the TUBGCP family. http://togogenome.org/gene/110368:LOC112055733 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYD1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112043419 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNZ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Cell projection|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/110368:LOC112047648 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC28 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/110368:LOC112058480 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB71 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. http://togogenome.org/gene/110368:LOC112043594 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. http://togogenome.org/gene/110368:LOC112051324 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP16 family.|||nucleolus http://togogenome.org/gene/110368:LOC112044716 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTZ0 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/110368:LOC112050535 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHX0 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112051398 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFQ0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112043562 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK78 ^@ Similarity ^@ Belongs to the TRIAP1/MDM35 family. http://togogenome.org/gene/110368:LOC112050470 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC73 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SF3B5 family.|||Component of the spliceosome B complex.|||Nucleus http://togogenome.org/gene/110368:LOC112058304 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAH1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047523 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050515 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCD0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL12 family. http://togogenome.org/gene/110368:LOC112052453 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR06 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/110368:LOC112058102 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9R6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112051295 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQZ4 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/110368:LOC112052285 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUN3 ^@ Similarity ^@ Belongs to the eukaryotic mitochondrial porin family. http://togogenome.org/gene/110368:LOC112057570 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7M6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/110368:LOC112055356 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWV4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/110368:LOC112052586 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047959 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7Q8 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/110368:LOC112045357 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWM9 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/110368:LOC112047485 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5K3|||http://purl.uniprot.org/uniprot/A0A6J1NBH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/110368:LOC112046475 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWC9|||http://purl.uniprot.org/uniprot/A0A6J1N137 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047161 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4B8 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/110368:LOC112043810 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGE1 ^@ Similarity ^@ Belongs to the SERBP1-HABP4 family. http://togogenome.org/gene/110368:LOC112051234 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NELF-D family.|||Nucleus http://togogenome.org/gene/110368:LOC112050218 ^@ http://purl.uniprot.org/uniprot/A0A6J1N926|||http://purl.uniprot.org/uniprot/A0A6J1NBB3|||http://purl.uniprot.org/uniprot/A0A6J1NGU0|||http://purl.uniprot.org/uniprot/A0A6J1NGU5|||http://purl.uniprot.org/uniprot/A0A6J1NGV0|||http://purl.uniprot.org/uniprot/A0A6J1NM25|||http://purl.uniprot.org/uniprot/A0A6J1NM29 ^@ Function|||Similarity ^@ Belongs to the troponin T family.|||Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. http://togogenome.org/gene/110368:LOC112045676 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY14 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112051313 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFF3|||http://purl.uniprot.org/uniprot/A0A6J1NL79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Nucleus http://togogenome.org/gene/110368:LOC112046565 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWR4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/110368:LOC112043401 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJL8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048429 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1K1 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/110368:LOC112053196 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU04 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057686 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B8 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/110368:LOC112056907 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5V7 ^@ Similarity ^@ Belongs to the PACS family. http://togogenome.org/gene/110368:LOC112051689 ^@ http://purl.uniprot.org/uniprot/A0A6J1NES1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/110368:LOC112051301 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND05 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112053924 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNL4|||http://purl.uniprot.org/uniprot/A0A6J1NVV1|||http://purl.uniprot.org/uniprot/A0A6J1P086 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/110368:LOC112047859 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCW6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112050834 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB24 ^@ Similarity ^@ Belongs to the peptidase M24 family. http://togogenome.org/gene/110368:LOC112044853 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUH1|||http://purl.uniprot.org/uniprot/A0A6J1MUQ5 ^@ Similarity ^@ Belongs to the PBP/GOBP family. http://togogenome.org/gene/110368:LOC112054859 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2C4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/110368:LOC112043178 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGG1 ^@ Similarity ^@ Belongs to the ABP1 family. http://togogenome.org/gene/110368:LOC112051961 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNV9 ^@ Function|||Similarity ^@ Belongs to the sorting nexin family.|||Involved in several stages of intracellular trafficking. http://togogenome.org/gene/110368:LOC112058540 ^@ http://purl.uniprot.org/uniprot/A0A6J1PC48 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/110368:LOC112052075 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNZ2|||http://purl.uniprot.org/uniprot/A0A6J1NPE6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.|||Membrane|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/110368:LOC112045257 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRL7|||http://purl.uniprot.org/uniprot/A0A6J1MW08|||http://purl.uniprot.org/uniprot/A0A6J1MW91 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/110368:LOC112055316 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit I family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112056064 ^@ http://purl.uniprot.org/uniprot/A0A6J1P480 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/110368:LOC112050363 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBU8 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 3 family.|||Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. http://togogenome.org/gene/110368:LOC112043716 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWW3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/110368:LOC112058274 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insect defense protein family.|||Secreted http://togogenome.org/gene/110368:LOC112051882 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFC3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/110368:LOC112055936 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM76 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049145 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCI0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/110368:LOC112045148 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN67|||http://purl.uniprot.org/uniprot/A0A6J1N292 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054995 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0N4 ^@ Similarity ^@ Belongs to the peptidase M67C family. http://togogenome.org/gene/110368:LOC112053801 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/110368:LOC112055872 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/110368:LOC112043307 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.|||Cytoplasm|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.|||May play a role in chaperone-mediated protein folding. http://togogenome.org/gene/110368:LOC112051834 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN16 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/110368:LOC112045155 ^@ http://purl.uniprot.org/uniprot/A0A6J1N298 ^@ Similarity ^@ Belongs to the FAM154 family. http://togogenome.org/gene/110368:LOC112048511 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9Y3 ^@ Similarity ^@ Belongs to the TTC21 family. http://togogenome.org/gene/110368:LOC112049414 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/110368:LOC112050164 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGL7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112042909 ^@ http://purl.uniprot.org/uniprot/A0A0B5KT02 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/110368:LOC112050736 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIM3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL6 family. http://togogenome.org/gene/110368:LOC112047961 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZP1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family. CLIP subfamily.|||Secreted|||The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure. http://togogenome.org/gene/110368:LOC112050500 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9Y1 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/110368:LOC112051779 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMW3|||http://purl.uniprot.org/uniprot/A0A6J1NN51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051066 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ18 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/110368:LOC112044666 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0H9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112053106 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTK1 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/110368:LOC112046230 ^@ http://purl.uniprot.org/uniprot/A0A6J1N077 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051652 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSC1 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/110368:LOC112043455 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP05 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/110368:LOC112054023 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRK7 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/110368:LOC112051115 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKB1 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/110368:LOC112047938 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7N3|||http://purl.uniprot.org/uniprot/A0A6J1ND85 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/110368:LOC112051626 ^@ http://purl.uniprot.org/uniprot/A0A6J1NED2|||http://purl.uniprot.org/uniprot/A0A6J1NGP1|||http://purl.uniprot.org/uniprot/A0A6J1NM81|||http://purl.uniprot.org/uniprot/A0A6J1NMF0|||http://purl.uniprot.org/uniprot/A0A6J1NS88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112050984 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJS5 ^@ Caution|||Similarity ^@ Belongs to the neurexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112043808 ^@ http://purl.uniprot.org/uniprot/A0A6J1MII6 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112053790 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZU1 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/110368:LOC112052714 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/110368:LOC112043149 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUS3 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/110368:LOC112049133 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/110368:LOC112051602 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. http://togogenome.org/gene/110368:LOC112051840 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/110368:LOC112044778 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/110368:LOC112049437 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIY2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/110368:LOC112053871 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Membrane http://togogenome.org/gene/110368:LOC112043303 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044488 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.|||Component of the pre-66S ribosomal particle.|||Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.|||nucleolus http://togogenome.org/gene/110368:LOC112044943 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/110368:LOC112043744 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGE9 ^@ Similarity ^@ Belongs to the WD repeat THOC6 family. http://togogenome.org/gene/110368:LOC112046964 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVB7 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/110368:LOC112054272 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPY2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/110368:LOC112055353 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0F1 ^@ Similarity ^@ Belongs to the SH2B adapter family. http://togogenome.org/gene/110368:LOC112055097 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-X family.|||Cytoplasm|||DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|||Nucleus http://togogenome.org/gene/110368:LOC112043615 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/110368:LOC112049561 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJG6 ^@ Similarity ^@ Belongs to the LSM12 family. http://togogenome.org/gene/110368:LOC112055063 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0X2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/110368:LOC112048101 ^@ http://purl.uniprot.org/uniprot/A0A6J1N083 ^@ Similarity ^@ Belongs to the NifU family. http://togogenome.org/gene/110368:LOC112052206 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUD9 ^@ Similarity ^@ Belongs to the IF-3 family. http://togogenome.org/gene/110368:LOC112043292 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/110368:LOC112050663 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCW7 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/110368:LOC112046346 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0R3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/110368:LOC112045197 ^@ http://purl.uniprot.org/uniprot/A0A6J1MND9 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/110368:LOC112044295 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSH7 ^@ Similarity ^@ Belongs to the NPC2 family. http://togogenome.org/gene/110368:LOC112052831 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRR5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/110368:LOC112044315 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112042876 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFF0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/110368:LOC112044820 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUD4 ^@ Similarity ^@ Belongs to the PBP/GOBP family. http://togogenome.org/gene/110368:LOC112052680 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIQ9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057954 ^@ http://purl.uniprot.org/uniprot/A0A6J1P965 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/110368:LOC112049078 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC76 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112045344 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112054323 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSU7|||http://purl.uniprot.org/uniprot/A0A6J1NYL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/110368:LOC112047795 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.|||nucleolus http://togogenome.org/gene/110368:LOC112046885 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/110368:LOC112048522 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9T9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112046735 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUF1|||http://purl.uniprot.org/uniprot/A0A6J1MXG3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112047286 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX26|||http://purl.uniprot.org/uniprot/A0A6J1N4X5 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/110368:LOC112043099 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMW9 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/110368:LOC112050225 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 49 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112049279 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCZ8 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/110368:LOC112044434 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSZ6 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/110368:LOC112044099 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ENY2 family.|||Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).|||Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.|||nucleoplasm http://togogenome.org/gene/110368:LOC112044613 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0A1 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/110368:LOC112043032 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI92 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/110368:LOC112047323 ^@ http://purl.uniprot.org/uniprot/A0A6J1N585 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M67A family. CSN6 subfamily.|||Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112044024 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF8 family.|||Nucleus http://togogenome.org/gene/110368:LOC112047941 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 15 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112044353 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSP8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/110368:LOC112052222 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.|||Belongs to the NPR3 family.|||Lysosome http://togogenome.org/gene/110368:LOC112050849 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDJ2 ^@ Similarity ^@ Belongs to the LAMTOR3 family. http://togogenome.org/gene/110368:LOC112053245 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKV0 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112048509 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFE0 ^@ Similarity ^@ Belongs to the peptidase M67A family. CSN5 subfamily. http://togogenome.org/gene/110368:LOC112045185 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNC7 ^@ Similarity ^@ Belongs to the TTC19 family. http://togogenome.org/gene/110368:LOC112052273 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ80 ^@ Function|||Similarity ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.|||Belongs to the glycosyl hydrolase 29 family. http://togogenome.org/gene/110368:LOC112053240 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTB3 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/110368:LOC112044858 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUL4 ^@ Similarity ^@ Belongs to the GIPC family. http://togogenome.org/gene/110368:LOC112056810 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5J7 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112047787 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.|||Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.|||cytoskeleton http://togogenome.org/gene/110368:LOC112054291 ^@ http://purl.uniprot.org/uniprot/A0A0B5L5V8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/110368:LOC112043345 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMIM8 family.|||Membrane http://togogenome.org/gene/110368:LOC112048610 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/110368:LOC112055218 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/110368:LOC112044347 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSP1 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/110368:LOC112055058 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSW8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme c group covalently per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112049259 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Q5|||http://purl.uniprot.org/uniprot/A0A6J1N7J4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112043533 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHN8|||http://purl.uniprot.org/uniprot/A0A6J1MK46 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/110368:LOC112058065 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9L4 ^@ Similarity ^@ Belongs to the DDRGK1 family. http://togogenome.org/gene/110368:LOC112050244 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGY4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112048819 ^@ http://purl.uniprot.org/uniprot/A0A6J1N316 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the APH-1 family.|||Membrane http://togogenome.org/gene/110368:LOC112054897 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZ39|||http://purl.uniprot.org/uniprot/A0A6J1P0E0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/110368:LOC112058117 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9R3 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/110368:LOC112042830 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||Nucleus http://togogenome.org/gene/110368:LOC112050046 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG26 ^@ Similarity ^@ Belongs to the Mo25 family. http://togogenome.org/gene/110368:LOC112056930 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5W1 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112052178 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ17 ^@ Similarity ^@ Belongs to the UPF0729 family. http://togogenome.org/gene/110368:LOC112048084 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDS6 ^@ Similarity ^@ Belongs to the Rho GDI family. http://togogenome.org/gene/110368:LOC112049965 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFS3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112048642 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAK4 ^@ Subcellular Location Annotation ^@ centrosome http://togogenome.org/gene/110368:LOC112044485 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT64 ^@ Function|||Similarity|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB4 subunit family.|||Complex I is composed of 45 different subunits. http://togogenome.org/gene/110368:LOC112051670 ^@ http://purl.uniprot.org/uniprot/A0A6J1NME5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 10 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112054219 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSC9 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/110368:LOC112051508 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG76|||http://purl.uniprot.org/uniprot/A0A6J1NRS1 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/110368:LOC112054896 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSB8|||http://purl.uniprot.org/uniprot/A0A6J1P2F0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043474 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJU4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/110368:LOC112044844 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUP1 ^@ Function|||Subcellular Location Annotation ^@ General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.|||Golgi apparatus|||Membrane|||Mitochondrion http://togogenome.org/gene/110368:LOC112048935 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBN6 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/110368:LOC112046413 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/110368:LOC112052473 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVD0 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/110368:LOC112048571 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051154 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKA7|||http://purl.uniprot.org/uniprot/A0A6J1NQD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MAP Jupiter family.|||Binds to all microtubule populations.|||Nucleus|||spindle http://togogenome.org/gene/110368:LOC112043412 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVS4 ^@ Similarity ^@ Belongs to the SCC3 family. http://togogenome.org/gene/110368:LOC112043072 ^@ http://purl.uniprot.org/uniprot/A0A6J1MID5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112044650 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112045707 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ68 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/110368:LOC112044345 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112047984 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntrophin family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112046560 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1I1 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/110368:LOC112055981 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112053843 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112057889 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8W1 ^@ Similarity ^@ Belongs to the NPR2 family. http://togogenome.org/gene/110368:LOC112044826 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM23 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/110368:LOC112051106 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047407 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5C2 ^@ Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.|||Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. http://togogenome.org/gene/110368:LOC112046158 ^@ http://purl.uniprot.org/uniprot/A0A6J1N637 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/110368:LOC112049093 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044041 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYA7 ^@ Similarity ^@ Belongs to the SH3BP5 family. http://togogenome.org/gene/110368:LOC112044334 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN36 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112045425 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS63 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045246 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2K3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053599 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 20 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112044609 ^@ http://purl.uniprot.org/uniprot/A0A6J1N094 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112057746 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8K2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112045161 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRA8 ^@ Similarity ^@ Belongs to the peptidase C13 family. http://togogenome.org/gene/110368:LOC112058450 ^@ http://purl.uniprot.org/uniprot/A0A6J1PB72 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/110368:LOC112052801 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRN1|||http://purl.uniprot.org/uniprot/A0A6J1NSF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/110368:LOC112046889 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112043574 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/110368:LOC112048039 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/110368:LOC112050501 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHX8 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/110368:LOC112044039 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJC8 ^@ Similarity ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. http://togogenome.org/gene/110368:LOC112052186 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/110368:LOC112050028 ^@ http://purl.uniprot.org/uniprot/A0A6J1N875 ^@ Similarity ^@ Belongs to the carnosine N-methyltransferase family. http://togogenome.org/gene/110368:LOC112045903 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGS family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112045181 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112049207 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCN9 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/110368:LOC112050282 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBJ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112045157 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2A4 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/110368:LOC112042966 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/110368:LOC112055259 ^@ http://purl.uniprot.org/uniprot/A0A6J1P028 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112051872 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFB0|||http://purl.uniprot.org/uniprot/A0A6J1NHM2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112057612 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7X3 ^@ Similarity ^@ Belongs to the histidine acid phosphatase family. MINPP1 subfamily. http://togogenome.org/gene/110368:LOC112047098 ^@ http://purl.uniprot.org/uniprot/A0A6J1N466 ^@ Similarity ^@ Belongs to the vacuolar ATPase subunit S1 family. http://togogenome.org/gene/110368:LOC112044094 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112047001 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYI4|||http://purl.uniprot.org/uniprot/A0A6J1N9C7|||http://purl.uniprot.org/uniprot/A0A6J1N9D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PUR DNA-binding protein family.|||Nucleus http://togogenome.org/gene/110368:LOC112052374 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S11 family.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/110368:LOC112044288 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ54|||http://purl.uniprot.org/uniprot/A0A6J1MZ59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/110368:LOC112058406 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAU3 ^@ Function|||Similarity ^@ Belongs to the VPS28 family.|||Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. http://togogenome.org/gene/110368:LOC112043599 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NDC1 family.|||Membrane|||Nucleus membrane|||nuclear pore complex http://togogenome.org/gene/110368:LOC112043156 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112058088 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9M5 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112042899 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FIP1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112052080 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG3 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112046002 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047077 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112045104 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVF8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112052176 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/110368:LOC112049264 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCV9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/110368:LOC112056506 ^@ http://purl.uniprot.org/uniprot/A0A6J1P119 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG14 family.|||Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane http://togogenome.org/gene/110368:LOC112043142 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lariat debranching enzyme family.|||Nucleus http://togogenome.org/gene/110368:LOC112044883 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/110368:LOC112045577 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3X1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112048996 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBV0 ^@ Similarity ^@ Belongs to the PIH1 family. http://togogenome.org/gene/110368:LOC112047225 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||cis-Golgi network http://togogenome.org/gene/110368:LOC112044628 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP60|||http://purl.uniprot.org/uniprot/A0A6J1N0C7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112053136 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKD7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112055704 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055654 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/110368:LOC112044080 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYE5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with UHRF2/NIRF.|||May be involved in cell cycle regulation.|||Nucleus http://togogenome.org/gene/110368:LOC112045219 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2G1 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112044035 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/110368:LOC112054297 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWZ6 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/110368:LOC112048735 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2Q1 ^@ Similarity ^@ Belongs to the palmitoyl-protein thioesterase family. http://togogenome.org/gene/110368:LOC112044891 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQB3 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/110368:LOC112047925 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7A2 ^@ Similarity ^@ Belongs to the PPC synthetase family. http://togogenome.org/gene/110368:LOC112053022 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJW6|||http://purl.uniprot.org/uniprot/A0A6J1NX87 ^@ Function|||Similarity ^@ Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.|||Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. http://togogenome.org/gene/110368:LOC112049684 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with ribosomal protein S21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/110368:LOC112045575 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPS4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112046870 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3A5 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/110368:LOC112051947 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNT9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/110368:LOC112047943 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7D6|||http://purl.uniprot.org/uniprot/A0A6J1N7P4|||http://purl.uniprot.org/uniprot/A0A6J1ND98 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112054397 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/110368:LOC112045905 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYZ6 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/110368:LOC112049334 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane http://togogenome.org/gene/110368:LOC112044301 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK63 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/110368:LOC112049937 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA57 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/110368:LOC112051381 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/110368:LOC112046600 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7Q9 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/110368:LOC112043900 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS54 family.|||trans-Golgi network http://togogenome.org/gene/110368:LOC112047945 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDA0 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/110368:LOC112054997 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112045867 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-16 family.|||Peroxisome membrane http://togogenome.org/gene/110368:LOC112047262 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/110368:LOC112044534 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNV9 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112052881 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJG4|||http://purl.uniprot.org/uniprot/A0A6J1NWT0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/110368:LOC112043550 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK69|||http://purl.uniprot.org/uniprot/A0A6J1MPK3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/110368:LOC112047587 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0X3|||http://purl.uniprot.org/uniprot/A0A6J1N5Y2|||http://purl.uniprot.org/uniprot/A0A6J1N668|||http://purl.uniprot.org/uniprot/A0A6J1NBT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112056333 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cleavage furrow|||Midbody|||cilium membrane|||spindle http://togogenome.org/gene/110368:LOC112045431 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3D9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112048231 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0S7 ^@ Similarity ^@ Belongs to the Tom22 family. http://togogenome.org/gene/110368:LOC112048503 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9Q2|||http://purl.uniprot.org/uniprot/A0A6J1NFD1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112043807 ^@ http://purl.uniprot.org/uniprot/A0A6J1ML81|||http://purl.uniprot.org/uniprot/A0A6J1MQJ1|||http://purl.uniprot.org/uniprot/A0A6J1MQN6|||http://purl.uniprot.org/uniprot/A0A6J1MXB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112046373 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0U8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family.|||Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.|||Homodimer. The active form is probably a hexamer composed of 3 homodimers. http://togogenome.org/gene/110368:LOC112057937 ^@ http://purl.uniprot.org/uniprot/A0A6J1P938 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/110368:LOC112047206 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112050186 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGP6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112047076 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3T5 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/110368:LOC112057670 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7Z1 ^@ Similarity ^@ Belongs to the parvin family. http://togogenome.org/gene/110368:LOC112054726 ^@ http://purl.uniprot.org/uniprot/A0A6J1P233 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/110368:LOC112050672 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNJ6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/110368:LOC112047427 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0E7 ^@ Similarity ^@ Belongs to the CCDC93 family. http://togogenome.org/gene/110368:LOC112053406 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOT1 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112043932 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIZ9 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/110368:LOC112045564 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXH8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/110368:LOC112047718 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112042976 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan. http://togogenome.org/gene/110368:LOC112047872 ^@ http://purl.uniprot.org/uniprot/A0A6J1N227|||http://purl.uniprot.org/uniprot/A0A6J1NCY6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.|||Homodimer; disulfide-linked.|||Membrane http://togogenome.org/gene/110368:LOC112046302 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0V0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112050083 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/110368:LOC112055727 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVG5|||http://purl.uniprot.org/uniprot/A0A6J1P1D6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M49 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/110368:LOC112051688 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSI9 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/110368:LOC112043203 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMY3 ^@ Similarity ^@ In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/110368:LOC112044947 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1J7 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/110368:LOC112047357 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB20 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/110368:LOC112055302 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWN8|||http://purl.uniprot.org/uniprot/A0A6J1P084 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/110368:LOC112048994 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHB3 ^@ Function|||Similarity ^@ Belongs to the EAF family.|||Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development. http://togogenome.org/gene/110368:LOC112055628 ^@ http://purl.uniprot.org/uniprot/A0A6J1P179 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase inhibitor family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112045313 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNT7|||http://purl.uniprot.org/uniprot/A0A6J1MRS8|||http://purl.uniprot.org/uniprot/A0A6J1MW89|||http://purl.uniprot.org/uniprot/A0A6J1MWG8|||http://purl.uniprot.org/uniprot/A0A6J1N2U0 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/110368:LOC112047893 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/110368:LOC112047207 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4I3 ^@ Similarity ^@ Belongs to the CIA30 family. http://togogenome.org/gene/110368:LOC112044018 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRF8 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. http://togogenome.org/gene/110368:LOC112052265 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPN3|||http://purl.uniprot.org/uniprot/A0A6J1NQ71 ^@ Similarity ^@ Belongs to the rogdi family. http://togogenome.org/gene/110368:LOC112045274 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW29 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/110368:LOC112050260 ^@ http://purl.uniprot.org/uniprot/A0A6J1N980 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/110368:LOC112048033 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZY7|||http://purl.uniprot.org/uniprot/A0A6J1N2P8|||http://purl.uniprot.org/uniprot/A0A6J1NDL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/110368:LOC112053571 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Synapse http://togogenome.org/gene/110368:LOC112042866 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP19 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112049962 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA79 ^@ Similarity|||Subunit ^@ Belongs to the ubiquitin-activating E1 family.|||Heterodimer. http://togogenome.org/gene/110368:LOC112045686 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4B0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112051386 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDD6|||http://purl.uniprot.org/uniprot/A0A6J1NFM9 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/110368:LOC112046364 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat Groucho/TLE family.|||Nucleus http://togogenome.org/gene/110368:LOC112049885 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7J2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112046008 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUK6 ^@ Similarity ^@ Belongs to the gonadal family. http://togogenome.org/gene/110368:LOC112054893 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIF beta subunit family.|||Nucleus|||TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. http://togogenome.org/gene/110368:LOC112044884 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUV6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/110368:LOC112056445 ^@ http://purl.uniprot.org/uniprot/A0A6J1P368|||http://purl.uniprot.org/uniprot/A0A6J1P3Y6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051454 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112049131 ^@ http://purl.uniprot.org/uniprot/A0A6J1N491|||http://purl.uniprot.org/uniprot/A0A6J1N752 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/110368:LOC112058362 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAQ5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/110368:LOC112044804 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044299 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane http://togogenome.org/gene/110368:LOC112045649 ^@ http://purl.uniprot.org/uniprot/A0A6J1N462 ^@ Similarity ^@ Belongs to the GLI C2H2-type zinc-finger protein family. http://togogenome.org/gene/110368:LOC112048662 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAI1 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/110368:LOC112043785 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQF0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/110368:LOC112046901 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/110368:LOC112044367 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZFPL1 family.|||Membrane http://togogenome.org/gene/110368:LOC112045725 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQB4|||http://purl.uniprot.org/uniprot/A0A6J1MTD6|||http://purl.uniprot.org/uniprot/A0A6J1MYA8|||http://purl.uniprot.org/uniprot/A0A6J1N4J9 ^@ Similarity ^@ Belongs to the IAP family. http://togogenome.org/gene/110368:LOC112051153 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sarcoglycan beta/delta/gamma/zeta family.|||cytoskeleton|||sarcolemma http://togogenome.org/gene/110368:LOC112048626 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2B4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pex2/pex10/pex12 family.|||Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.|||Membrane|||Peroxisome membrane http://togogenome.org/gene/110368:LOC112046601 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1P1 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/110368:LOC112058490 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBX1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 22 family. http://togogenome.org/gene/110368:LOC112055940 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||Structural component of the gap junctions.|||gap junction http://togogenome.org/gene/110368:LOC112052611 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRN5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112045731 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112054543 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit G family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. http://togogenome.org/gene/110368:LOC112047809 ^@ http://purl.uniprot.org/uniprot/A0A6J1N732 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.|||Nucleus http://togogenome.org/gene/110368:LOC112055180 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW77|||http://purl.uniprot.org/uniprot/A0A6J1P172 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/110368:LOC112045149 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVL7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112046881 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2X5|||http://purl.uniprot.org/uniprot/A0A6J1N3B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/110368:LOC112045353 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRX6|||http://purl.uniprot.org/uniprot/A0A6J1MWM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/110368:LOC112054251 ^@ http://purl.uniprot.org/uniprot/A0A6J1NWV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/110368:LOC112046017 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUL7 ^@ Similarity ^@ Belongs to the SIKE family. http://togogenome.org/gene/110368:LOC112044985 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMK6 ^@ Similarity ^@ Belongs to the TTC36 family. http://togogenome.org/gene/110368:LOC112054443 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTC9 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/110368:LOC112044051 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM76 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051246 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKX4 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/110368:LOC112050140 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DCP2 subfamily. http://togogenome.org/gene/110368:LOC112045494 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane http://togogenome.org/gene/110368:LOC112049197 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112048048 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/110368:LOC112048729 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112045802 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/110368:LOC112051942 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TSSC4 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112045311 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2T2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).|||Nucleus http://togogenome.org/gene/110368:LOC112054105 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112052910 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS04 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/110368:LOC112045574 ^@ http://purl.uniprot.org/uniprot/A0A6J1MST7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112050166 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLV7 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/110368:LOC112049191 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCL1|||http://purl.uniprot.org/uniprot/A0A6J1NI10 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/110368:LOC112047204 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112049696 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052928 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043689 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/110368:LOC112053167 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXT0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL18 family. http://togogenome.org/gene/110368:LOC112049507 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDW4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112043215 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase IV family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112051039 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112048683 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2J5 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/110368:LOC112043845 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQQ3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112044001 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Membrane http://togogenome.org/gene/110368:LOC112043568 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHS1|||http://purl.uniprot.org/uniprot/A0A6J1MK86 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/110368:LOC112042958 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLX7 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/110368:LOC112056230 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXR1|||http://purl.uniprot.org/uniprot/A0A6J1P4C3 ^@ Similarity ^@ Belongs to the mastermind family. http://togogenome.org/gene/110368:LOC112050960 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/110368:LOC112045179 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVR0 ^@ Cofactor ^@ Binds one Zn(2+) ion per subunit. http://togogenome.org/gene/110368:LOC112052236 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGU1 ^@ Similarity ^@ Belongs to the NOC2 family. http://togogenome.org/gene/110368:LOC112050066 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG55|||http://purl.uniprot.org/uniprot/A0A6J1NLF1 ^@ Similarity ^@ Belongs to the centaurin gamma-like family. http://togogenome.org/gene/110368:LOC112047432 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0F2 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/110368:LOC112047282 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4W1|||http://purl.uniprot.org/uniprot/A0A6J1N529 ^@ Similarity ^@ Belongs to the poly(ADP-ribose) glycohydrolase family. http://togogenome.org/gene/110368:LOC112043664 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047722 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1G8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/110368:LOC112050759 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAT9 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112048660 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112052627 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the milton family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112053769 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112053480 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV50 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/110368:LOC112058580 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBK1 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/110368:LOC112054336 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYN5 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/110368:LOC112047387 ^@ http://purl.uniprot.org/uniprot/A0A6J1N099 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/110368:LOC112043569 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHS5 ^@ Similarity ^@ Belongs to the nanos family. http://togogenome.org/gene/110368:LOC112046270 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVR6|||http://purl.uniprot.org/uniprot/A0A6J1N0F4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046187 ^@ http://purl.uniprot.org/uniprot/A0A6J1N003|||http://purl.uniprot.org/uniprot/A0A6J1N0B6|||http://purl.uniprot.org/uniprot/A0A6J1N6A7 ^@ Subcellular Location Annotation ^@ Synapse|||axon|||dendritic spine http://togogenome.org/gene/110368:LOC112048924 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6B4 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112046879 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTU2/NCS2 family.|||Cytoplasm|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. http://togogenome.org/gene/110368:LOC112051864 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHL4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGW family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. http://togogenome.org/gene/110368:LOC112048284 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8W5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055618 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC6 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112050542 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCF8 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/110368:LOC112057774 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112043704 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKR0 ^@ Subcellular Location Annotation ^@ sarcolemma http://togogenome.org/gene/110368:LOC112044371 ^@ http://purl.uniprot.org/uniprot/A0A6J1MST1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL40 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112052184 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGM0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046820 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/110368:LOC112056474 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC3 family.|||Membrane http://togogenome.org/gene/110368:LOC112044356 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSR1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/110368:LOC112054673 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU92 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112046328 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0Y0 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/110368:LOC112051338 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR44 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112053105 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSS1 ^@ Similarity ^@ Belongs to the protein phosphatase inhibitor 2 family. http://togogenome.org/gene/110368:LOC112048341 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9C3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112057834 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8I3|||http://purl.uniprot.org/uniprot/A0A6J1P8L1|||http://purl.uniprot.org/uniprot/A0A6J1P8L2|||http://purl.uniprot.org/uniprot/A0A6J1P8M7 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/110368:LOC112048167 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8J7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ITPK1 family.|||Binds 2 magnesium ions per subunit.|||Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.|||Monomer. http://togogenome.org/gene/110368:LOC112044520 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043210 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNA0|||http://purl.uniprot.org/uniprot/A0A6J1MUZ8 ^@ Similarity ^@ Belongs to the FAM151 family. http://togogenome.org/gene/110368:LOC112051225 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/110368:LOC112050783 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043139 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052898 ^@ http://purl.uniprot.org/uniprot/A0A6J1NST2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112052774 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLF0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112055935 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRC4 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112046701 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX80|||http://purl.uniprot.org/uniprot/A0A6J1N255 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045909 ^@ http://purl.uniprot.org/uniprot/A0A6J1MU52 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043997 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLY3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.|||Cytoplasm|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. http://togogenome.org/gene/110368:LOC112057655 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7X9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/110368:LOC112054372 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1E1 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112050775 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112058153 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELOF1 family.|||Nucleus|||Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. http://togogenome.org/gene/110368:LOC112046680 ^@ http://purl.uniprot.org/uniprot/A0A0B5L9U3 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/110368:LOC112043492 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW57 ^@ Function|||Similarity ^@ Belongs to the IPP isomerase type 1 family.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/110368:LOC112055964 ^@ http://purl.uniprot.org/uniprot/A0A6J1P204 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/110368:LOC112044607 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTM7 ^@ Similarity|||Subunit ^@ Belongs to the cyclin-dependent kinase 5 activator family.|||Heterodimer of a catalytic subunit and a regulatory subunit. http://togogenome.org/gene/110368:LOC112043496 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW62 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/110368:LOC112047248 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112056349 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/110368:LOC112043473 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVZ5|||http://purl.uniprot.org/uniprot/A0A6J1MW17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Orai family.|||Membrane http://togogenome.org/gene/110368:LOC112045579 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXL4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112045585 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXM3|||http://purl.uniprot.org/uniprot/A0A6J1N3X8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045951 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYW7|||http://purl.uniprot.org/uniprot/A0A6J1MZ60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112050522 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/110368:LOC112054705 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit J family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/110368:LOC112046891 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112049169 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCK2 ^@ Subcellular Location Annotation|||Subunit ^@ Endoplasmic reticulum|||Golgi apparatus|||Homodimer. The monomeric form is inactive while the homodimer is active.|||Lysosome http://togogenome.org/gene/110368:LOC112056543 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4L4 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/110368:LOC112048209 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112054071 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112044042 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJD2|||http://purl.uniprot.org/uniprot/A0A6J1MRN3 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/110368:LOC112046526 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1P5|||http://purl.uniprot.org/uniprot/A0A6J1N7H3 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/110368:LOC112057696 ^@ http://purl.uniprot.org/uniprot/A0A6J1P803 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane http://togogenome.org/gene/110368:LOC112053453 ^@ http://purl.uniprot.org/uniprot/A0A6J1NP02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Nucleus http://togogenome.org/gene/110368:LOC112058258 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAA7 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112044829 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA11 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046576 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7P6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045130 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR68 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112047677 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1A9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/110368:LOC112044401 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNA6 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/110368:LOC112049544 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8N8 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/110368:LOC112052992 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metaxin family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/110368:LOC112044815 ^@ http://purl.uniprot.org/uniprot/A0A6J1N125 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/110368:LOC112053289 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTH3 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112057232 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112046437 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT62 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112052723 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052350 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQK3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small Tim family.|||Heterohexamer.|||Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.|||Mitochondrion inner membrane|||The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. http://togogenome.org/gene/110368:LOC112055523 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXM0|||http://purl.uniprot.org/uniprot/A0A6J1P3L2 ^@ Similarity ^@ Belongs to the eukaryotic ATPase epsilon family. http://togogenome.org/gene/110368:LOC112054360 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT22 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112052570 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVS3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/110368:LOC112044233 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS82 ^@ Similarity ^@ Belongs to the complex I NDUFA12 subunit family. http://togogenome.org/gene/110368:LOC112056882 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5R6 ^@ Similarity ^@ Belongs to the vinculin/alpha-catenin family. http://togogenome.org/gene/110368:LOC112051663 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGU2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045350 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112054461 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1K0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053567 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPJ0 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112051203 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATG12 family.|||Forms a conjugate with ATG5.|||Ubiquitin-like protein involved in autophagic vesicle formation. http://togogenome.org/gene/110368:LOC112045501 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPJ6|||http://purl.uniprot.org/uniprot/A0A6J1N3M0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044994 ^@ http://purl.uniprot.org/uniprot/A0A6J1MV06|||http://purl.uniprot.org/uniprot/A0A6J1N1Q3 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/110368:LOC112048705 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112055096 ^@ http://purl.uniprot.org/uniprot/A0A6J1NT37 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/110368:LOC112053139 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMQ8 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/110368:LOC112043692 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/110368:LOC112043680 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWS5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/110368:LOC112055066 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSX9 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/110368:LOC112048770 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC62 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112051557 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLZ7 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/110368:LOC112051236 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF47 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/110368:LOC112050527 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA14|||http://purl.uniprot.org/uniprot/A0A6J1NCE2|||http://purl.uniprot.org/uniprot/A0A6J1NHW0|||http://purl.uniprot.org/uniprot/A0A6J1NI14|||http://purl.uniprot.org/uniprot/A0A6J1NN32 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112046007 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZG0 ^@ Similarity ^@ Belongs to the EAF6 family. http://togogenome.org/gene/110368:LOC112046282 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSQ2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/110368:LOC112052854 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLP4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112054187 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0Y8 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/110368:LOC112049389 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112048328 ^@ http://purl.uniprot.org/uniprot/A0A6J1N160 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112052230 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP SmB/SmN family.|||Nucleus http://togogenome.org/gene/110368:LOC112045572 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSS2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/110368:LOC112051356 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046228 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSG7 ^@ Similarity ^@ Belongs to the SLBP family. http://togogenome.org/gene/110368:LOC112056851 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112047700 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112047358 ^@ http://purl.uniprot.org/uniprot/A0A6J1N556 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 29 family.|||Nucleus http://togogenome.org/gene/110368:LOC112042900 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTS0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112046890 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2Z4|||http://purl.uniprot.org/uniprot/A0A6J1N8W7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112056843 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112042864 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHK3|||http://purl.uniprot.org/uniprot/A0A6J1MLM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/110368:LOC112044814 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUC3 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/110368:LOC112054151 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0U6 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/110368:LOC112048100 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2Y6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/110368:LOC112050411 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112045363 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWG5|||http://purl.uniprot.org/uniprot/A0A6J1MWN9 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/110368:LOC112054265 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPX2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M10A family.|||Binds 2 Zn(2+) ions per subunit.|||Can bind about 5 Ca(2+) ions per subunit. http://togogenome.org/gene/110368:LOC112054834 ^@ http://purl.uniprot.org/uniprot/A0A6J1P066 ^@ Similarity|||Subunit ^@ Belongs to the casein kinase 2 subunit beta family.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/110368:LOC112043772 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQC6|||http://purl.uniprot.org/uniprot/A0A6J1MQF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051826 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNB6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112057907 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8Y2|||http://purl.uniprot.org/uniprot/A0A6J1P910 ^@ Function|||Similarity ^@ Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis. http://togogenome.org/gene/110368:LOC112046419 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW68 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm|||Endoplasmic reticulum|||The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.|||The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. http://togogenome.org/gene/110368:LOC112056883 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5N3|||http://purl.uniprot.org/uniprot/A0A6J1P5S4 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/110368:LOC112047832 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ62 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/110368:LOC112057745 ^@ http://purl.uniprot.org/uniprot/A0A6J1P886 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112047169 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA76 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/110368:LOC112048559 ^@ http://purl.uniprot.org/uniprot/A0A6J1NA63 ^@ Similarity ^@ Belongs to the HMGA family. http://togogenome.org/gene/110368:LOC112047789 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/110368:LOC112058556 ^@ http://purl.uniprot.org/uniprot/A0A6J1PC65 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/110368:LOC112047931 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZK3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043570 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWE7 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/110368:LOC112051794 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMX1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112043675 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKM4|||http://purl.uniprot.org/uniprot/A0A6J1MPY3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112046519 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1A3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112049253 ^@ http://purl.uniprot.org/uniprot/A0A6J1NI73 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.|||Cell membrane|||Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112057966 ^@ http://purl.uniprot.org/uniprot/A0A6J1P975 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/110368:LOC112048387 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF23 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051261 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112056132 ^@ http://purl.uniprot.org/uniprot/A0A6J1P497 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112053907 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dpy-19 family.|||Membrane http://togogenome.org/gene/110368:LOC112055412 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112048525 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1W1|||http://purl.uniprot.org/uniprot/A0A6J1NA12|||http://purl.uniprot.org/uniprot/A0A6J1NFH3 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/110368:LOC112048901 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/110368:LOC112050391 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBX7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112043714 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKS5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. http://togogenome.org/gene/110368:LOC112047902 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047484 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112046218 ^@ http://purl.uniprot.org/uniprot/A0A6J1N059 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/110368:LOC112051026 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBW9|||http://purl.uniprot.org/uniprot/A0A6J1NEB0|||http://purl.uniprot.org/uniprot/A0A6J1NPX6 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/110368:LOC112049313 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112049113 ^@ http://purl.uniprot.org/uniprot/A0A6J1N459 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112057729 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.|||Membrane http://togogenome.org/gene/110368:LOC112049941 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFM7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/110368:LOC112049174 ^@ http://purl.uniprot.org/uniprot/A0A6J1N799 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/110368:LOC112048950 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6E3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Component of the signal peptidase complex.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112053158 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSY5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the myo-inositol oxygenase family.|||Binds 2 iron ions per subunit.|||Cytoplasm http://togogenome.org/gene/110368:LOC112058357 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAS1 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/110368:LOC112048262 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3P4|||http://purl.uniprot.org/uniprot/A0A6J1N917 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/110368:LOC112048389 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1E1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/110368:LOC112046107 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZX5 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/110368:LOC112046120 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZZ4 ^@ Similarity ^@ Belongs to the uroporphyrinogen-III synthase family. http://togogenome.org/gene/110368:LOC112056835 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5L2 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/110368:LOC112043134 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIL4|||http://purl.uniprot.org/uniprot/A0A6J1MMM5|||http://purl.uniprot.org/uniprot/A0A6J1MN03 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/110368:LOC112051374 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLF3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/110368:LOC112046044 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUQ9 ^@ Similarity ^@ Belongs to the SF3A2 family. http://togogenome.org/gene/110368:LOC112051755 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEX6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112054718 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SWEET sugar transporter family.|||Cell membrane|||Golgi apparatus membrane|||Mediates sugar transport across membranes.|||Membrane http://togogenome.org/gene/110368:LOC112054758 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRS7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051286 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCY7 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/110368:LOC112051065 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112055823 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/110368:LOC112045108 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR43 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/110368:LOC112048958 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/110368:LOC112046539 ^@ http://purl.uniprot.org/uniprot/A0A6J1N7J7 ^@ Similarity ^@ Belongs to the GSKIP family. http://togogenome.org/gene/110368:LOC112044489 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZV8 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/110368:LOC112050905 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112044878 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUJ8 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus http://togogenome.org/gene/110368:LOC112043027 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFY2|||http://purl.uniprot.org/uniprot/A0A6J1MI84|||http://purl.uniprot.org/uniprot/A0A6J1MU99 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/110368:LOC112044514 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/110368:LOC112044156 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRY7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/110368:LOC112042918 ^@ http://purl.uniprot.org/uniprot/A0A6J1MFJ4 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/110368:LOC112048640 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2D7|||http://purl.uniprot.org/uniprot/A0A6J1N5A8|||http://purl.uniprot.org/uniprot/A0A6J1NG18 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/110368:LOC112052177 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPU3 ^@ Similarity ^@ Belongs to the TRAPPC13 family. http://togogenome.org/gene/110368:LOC112057944 ^@ http://purl.uniprot.org/uniprot/A0A6J1P927 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/110368:LOC112050222 ^@ http://purl.uniprot.org/uniprot/A0A6J1N935 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. http://togogenome.org/gene/110368:LOC112050893 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDS3 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. http://togogenome.org/gene/110368:LOC112050383 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9J7 ^@ Similarity ^@ Belongs to the GDNFR family. http://togogenome.org/gene/110368:LOC112058252 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA55|||http://purl.uniprot.org/uniprot/A0A6J1PA85 ^@ Subcellular Location Annotation ^@ Golgi apparatus|||centrosome http://togogenome.org/gene/110368:LOC112053373 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/110368:LOC112052332 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJL6 ^@ Similarity ^@ Belongs to the DEF8 family. http://togogenome.org/gene/110368:LOC112046799 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2L9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/110368:LOC112044376 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKF0 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/110368:LOC112043077 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMT8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112048941 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3G6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/110368:LOC112049615 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS16 family.|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. http://togogenome.org/gene/110368:LOC112047709 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052921 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/110368:LOC112048892 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIG1 family.|||Membrane http://togogenome.org/gene/110368:LOC112050263 ^@ http://purl.uniprot.org/uniprot/A0A6J1N984 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 6c family. http://togogenome.org/gene/110368:LOC112045930 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR27 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26 family. IMP2 subfamily.|||Heterodimer of 2 subunits, IMMPL1 and IMMPL2.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112046377 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW45 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/110368:LOC112044103 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112046670 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX30 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/110368:LOC112043217 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/110368:LOC112043331 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNG7|||http://purl.uniprot.org/uniprot/A0A6J1MNM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter. http://togogenome.org/gene/110368:LOC112057076 ^@ http://purl.uniprot.org/uniprot/A0A6J1P6B0 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/110368:LOC112048304 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9B1 ^@ Similarity ^@ Belongs to the lin-28 family. http://togogenome.org/gene/110368:LOC112047610 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Catalyzes juvenile hormone hydrolysis.|||Endoplasmic reticulum membrane http://togogenome.org/gene/110368:LOC112047405 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXJ8 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/110368:LOC112050541 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHX6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112052386 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/110368:LOC112055018 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZF6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112044894 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM98|||http://purl.uniprot.org/uniprot/A0A6J1MMA6|||http://purl.uniprot.org/uniprot/A0A6J1MUY9 ^@ Similarity ^@ Belongs to the MAGUK family. http://togogenome.org/gene/110368:LOC112045065 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMX1 ^@ Similarity ^@ Belongs to the NFYB/HAP3 subunit family. http://togogenome.org/gene/110368:LOC112054441 ^@ http://purl.uniprot.org/uniprot/A0A6J1NXL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112048392 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1E6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. http://togogenome.org/gene/110368:LOC112046531 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112053171 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKI3|||http://purl.uniprot.org/uniprot/A0A6J1NXT4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus speckle|||nuclear body http://togogenome.org/gene/110368:LOC112058574 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBV3|||http://purl.uniprot.org/uniprot/A0A6J1PC81 ^@ Similarity ^@ Belongs to the glycosyltransferase 65 family. http://togogenome.org/gene/110368:LOC112046421 ^@ http://purl.uniprot.org/uniprot/A0A6J1MT47|||http://purl.uniprot.org/uniprot/A0A6J1N729 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/110368:LOC112056647 ^@ http://purl.uniprot.org/uniprot/A0A6J1P507 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/110368:LOC112049271 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCX4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053835 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/110368:LOC112053305 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL20 ^@ Function|||Similarity ^@ Belongs to the TFIIE alpha subunit family.|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. http://togogenome.org/gene/110368:LOC112045525 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSJ7|||http://purl.uniprot.org/uniprot/A0A6J1N3M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047037 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112044296 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK58 ^@ Similarity ^@ Belongs to the NPC2 family. http://togogenome.org/gene/110368:LOC112044702 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTW3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112058319 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAH0 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/110368:LOC112049153 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4D0 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/110368:LOC112045183 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2C4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/110368:LOC112054350 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQB1|||http://purl.uniprot.org/uniprot/A0A6J1NSZ5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112047735 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6S5 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112055175 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZV2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/110368:LOC112044476 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Vang family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112051709 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/110368:LOC112045292 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW54|||http://purl.uniprot.org/uniprot/A0A6J1N2Q6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112050178 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRC4 ^@ Similarity ^@ Belongs to the HARBI1 family. http://togogenome.org/gene/110368:LOC112049826 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112051613 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM65 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112056678 ^@ http://purl.uniprot.org/uniprot/A0A6J1P510 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044948 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQI9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112045468 ^@ http://purl.uniprot.org/uniprot/A0A0B5KT04 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/110368:LOC112054597 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer; active form. Homohexamer; low activity form. http://togogenome.org/gene/110368:LOC112058411 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052290 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJH3 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/110368:LOC112044856 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUH9|||http://purl.uniprot.org/uniprot/A0A6J1N181 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112053837 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQR7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/110368:LOC112049746 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6Y0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/110368:LOC112057771 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8B4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112042801 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHD3|||http://purl.uniprot.org/uniprot/A0A6J1MTB6 ^@ Function|||Similarity ^@ Belongs to the proline oxidase family.|||Converts proline to delta-1-pyrroline-5-carboxylate. http://togogenome.org/gene/110368:LOC112055643 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3S4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112043572 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK92 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/110368:LOC112057847 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/110368:LOC112044358 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||DNA polymerase II participates in chromosomal DNA replication.|||Nucleus http://togogenome.org/gene/110368:LOC112045048 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1X7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/110368:LOC112052190 ^@ http://purl.uniprot.org/uniprot/A0A6J1NGN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112052356 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJR0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112048679 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112054485 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQR8|||http://purl.uniprot.org/uniprot/A0A6J1NZ33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.|||Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044267 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSE4 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/110368:LOC112051589 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM44 ^@ Similarity ^@ Belongs to the chorion protein family. http://togogenome.org/gene/110368:LOC112045384 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWS1 ^@ Similarity ^@ Belongs to the SLX4 family. http://togogenome.org/gene/110368:LOC112043667 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. http://togogenome.org/gene/110368:LOC112044659 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLD2 ^@ Similarity ^@ Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily. http://togogenome.org/gene/110368:LOC112052192 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPW3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/110368:LOC112043536 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHP3|||http://purl.uniprot.org/uniprot/A0A6J1MPH2|||http://purl.uniprot.org/uniprot/A0A6J1MPH6 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/110368:LOC112051691 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/110368:LOC112057904 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8Z8|||http://purl.uniprot.org/uniprot/A0A6J1P905 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphoglycerate mutase family. http://togogenome.org/gene/110368:LOC112051774 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHB2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/110368:LOC112055298 ^@ http://purl.uniprot.org/uniprot/A0A6J1P365 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/110368:LOC112047815 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ47 ^@ Similarity ^@ Belongs to the SNAP family. http://togogenome.org/gene/110368:LOC112044793 ^@ http://purl.uniprot.org/uniprot/A0A0B5KXM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/110368:LOC112045801 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY89 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/110368:LOC112044647 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PP2C family.|||Membrane|||cytosol http://togogenome.org/gene/110368:LOC112043625 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPS5 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/110368:LOC112049645 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEI0|||http://purl.uniprot.org/uniprot/A0A6J1NJT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/110368:LOC112047046 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/110368:LOC112047926 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043871 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR16 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112045578 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXC3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112053690 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQ26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-delta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/110368:LOC112043741 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGM1|||http://purl.uniprot.org/uniprot/A0A6J1MI96 ^@ Similarity ^@ Belongs to the histidine acid phosphatase family. MINPP1 subfamily. http://togogenome.org/gene/110368:LOC112054606 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTZ9|||http://purl.uniprot.org/uniprot/A0A6J1NY72|||http://purl.uniprot.org/uniprot/A0A6J1NZH2 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/110368:LOC112046448 ^@ http://purl.uniprot.org/uniprot/A0A6J1N113 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Component of the 40S small ribosomal subunit.|||Endoplasmic reticulum|||Rough endoplasmic reticulum|||cytosol http://togogenome.org/gene/110368:LOC112045245 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRK2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053314 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057925 ^@ http://purl.uniprot.org/uniprot/A0A6J1P904 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.|||Component of a multi-subunit COQ enzyme complex.|||Mitochondrion inner membrane|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/110368:LOC112046664 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX20 ^@ Similarity ^@ Belongs to the proteasome subunit S3 family. http://togogenome.org/gene/110368:LOC112046904 ^@ http://purl.uniprot.org/uniprot/A0A6J1N313 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/110368:LOC112056630 ^@ http://purl.uniprot.org/uniprot/A0A6J1P502 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/110368:LOC112044087 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRT0 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/110368:LOC112049055 ^@ http://purl.uniprot.org/uniprot/A0A6J1NC17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/110368:LOC112054218 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPV8|||http://purl.uniprot.org/uniprot/A0A6J1NQA6|||http://purl.uniprot.org/uniprot/A0A6J1P184 ^@ Similarity ^@ Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. http://togogenome.org/gene/110368:LOC112051107 ^@ http://purl.uniprot.org/uniprot/A0A0B5KXM5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/110368:LOC112053159 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKG7|||http://purl.uniprot.org/uniprot/A0A6J1NMT4|||http://purl.uniprot.org/uniprot/A0A6J1NMT9|||http://purl.uniprot.org/uniprot/A0A6J1NTV5|||http://purl.uniprot.org/uniprot/A0A6J1NTW0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112051523 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLW1|||http://purl.uniprot.org/uniprot/A0A6J1NRU9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112051403 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDG6|||http://purl.uniprot.org/uniprot/A0A6J1NLD2|||http://purl.uniprot.org/uniprot/A0A6J1NLJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/110368:LOC112043057 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SEC5 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|||Component of the exocyst complex. http://togogenome.org/gene/110368:LOC112051762 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMT7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/110368:LOC112052775 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ38 ^@ Similarity ^@ Belongs to the DDA1 family. http://togogenome.org/gene/110368:LOC112056799 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5I5 ^@ Subcellular Location Annotation ^@ A band|||Z line|||perinuclear region http://togogenome.org/gene/110368:LOC112053148 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTU0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/110368:LOC112044342 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN41 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/110368:LOC112043083 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUG8 ^@ Similarity ^@ Belongs to the PSMG1 family. http://togogenome.org/gene/110368:LOC112047603 ^@ http://purl.uniprot.org/uniprot/A0A6J1N606 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS37 family.|||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|||Late endosome membrane http://togogenome.org/gene/110368:LOC112043144 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMP2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112045300 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWE6 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/110368:LOC112048335 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEP1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112053914 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVT1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/110368:LOC112048962 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBM2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/110368:LOC112054262 ^@ http://purl.uniprot.org/uniprot/A0A6J1P146 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 19 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/110368:LOC112048378 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEW1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/110368:LOC112058240 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dolichyldiphosphatase family.|||Endoplasmic reticulum membrane|||Membrane|||Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. http://togogenome.org/gene/110368:LOC112055742 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2K9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112057569 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7U9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGV family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.|||Membrane http://togogenome.org/gene/110368:LOC112058313 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAW0 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/110368:LOC112049370 ^@ http://purl.uniprot.org/uniprot/A0A6J1N565|||http://purl.uniprot.org/uniprot/A0A6J1NDA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112051512 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112057481 ^@ http://purl.uniprot.org/uniprot/A0A6J1P782 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DRC9 family.|||flagellum|||flagellum axoneme http://togogenome.org/gene/110368:LOC112050746 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIN8 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/110368:LOC112050955 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/110368:LOC112054895 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV54 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/110368:LOC112054286 ^@ http://purl.uniprot.org/uniprot/A0A6J1P162 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS31 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112049204 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCM7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/110368:LOC112043282 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGR7|||http://purl.uniprot.org/uniprot/A0A6J1MJ43 ^@ Subunit ^@ Homodimer. Interacts with PKM. http://togogenome.org/gene/110368:LOC112057739 ^@ http://purl.uniprot.org/uniprot/A0A6J1P884 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS26 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112048605 ^@ http://purl.uniprot.org/uniprot/A0A6J1N563 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112042853 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHI3 ^@ Function|||Similarity ^@ Belongs to the CTP synthase family.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. http://togogenome.org/gene/110368:LOC112053890 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-6 family.|||Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.|||Cytoplasm|||Monomer. Associates with the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/110368:LOC112050931 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJJ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/110368:LOC112048095 ^@ http://purl.uniprot.org/uniprot/A0A6J1N821 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/110368:LOC112046528 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWL0|||http://purl.uniprot.org/uniprot/A0A6J1N1D8 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/110368:LOC112046786 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXM4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/110368:LOC112053565 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUF0 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/110368:LOC112043943 ^@ http://purl.uniprot.org/uniprot/W5QMG3 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/110368:LOC112052599 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112055526 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUS1|||http://purl.uniprot.org/uniprot/A0A6J1P0Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112049395 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5A2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/110368:LOC112052414 ^@ http://purl.uniprot.org/uniprot/A0A6J1NQT8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/110368:LOC112046741 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS4 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055626 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY26 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112047947 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/110368:LOC112048142 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8G8 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. http://togogenome.org/gene/110368:LOC112045348 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWL6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/110368:LOC112057664 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7V9|||http://purl.uniprot.org/uniprot/A0A6J1P7X7|||http://purl.uniprot.org/uniprot/A0A6J1P820|||http://purl.uniprot.org/uniprot/A0A6J1P878|||http://purl.uniprot.org/uniprot/A0A6J1P883 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shaker potassium channel beta subunit family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112042790 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLC1 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/110368:LOC112049065 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/110368:LOC112047501 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.|||cilium http://togogenome.org/gene/110368:LOC112044487 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNP7 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/110368:LOC112048165 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112043561 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF1 family.|||nucleolus http://togogenome.org/gene/110368:LOC112055104 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2U8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/110368:LOC112048115 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8C6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the deoxyhypusine hydroxylase family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. http://togogenome.org/gene/110368:LOC112052024 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/110368:LOC112043308 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNJ4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/110368:LOC112056070 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112047325 ^@ http://purl.uniprot.org/uniprot/A0A6J1MX85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/110368:LOC112045804 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTQ4|||http://purl.uniprot.org/uniprot/A0A6J1MY94 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112047785 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6R4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-91 and Arg-94) that bind to malonylated and succinylated substrates and define the specificity.|||Mitochondrion|||NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. http://togogenome.org/gene/110368:LOC112053654 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVU0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/110368:LOC112046222 ^@ http://purl.uniprot.org/uniprot/A0A6J1N6G0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/110368:LOC112045582 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXC8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/110368:LOC112044649 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLB4|||http://purl.uniprot.org/uniprot/A0A6J1N0F0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/110368:LOC112043421 ^@ http://purl.uniprot.org/uniprot/A0A6J1MH95 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112057881 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8T0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL27 family. http://togogenome.org/gene/110368:LOC112043332 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVG6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/110368:LOC112043894 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCO1/2 family.|||Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.|||Homodimer.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112058351 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.|||Nucleus http://togogenome.org/gene/110368:LOC112043920 ^@ http://purl.uniprot.org/uniprot/A0A6J1MIX8|||http://purl.uniprot.org/uniprot/A0A6J1MXS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/110368:LOC112058472 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112054216 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY70 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112051503 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG71 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/110368:LOC112052645 ^@ http://purl.uniprot.org/uniprot/A0A6J1NR39 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/110368:LOC112050373 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBW0 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/110368:LOC112050389 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHG3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/110368:LOC112045736 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXZ6 ^@ Function|||Similarity ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. http://togogenome.org/gene/110368:LOC112043209 ^@ http://purl.uniprot.org/uniprot/A0A6J1MGJ1 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/110368:LOC112053787 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVA7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M2 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/110368:LOC112043639 ^@ http://purl.uniprot.org/uniprot/A0A6J1MHY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRINL1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112048234 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3K7|||http://purl.uniprot.org/uniprot/A0A6J1N8P9|||http://purl.uniprot.org/uniprot/A0A6J1NED3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 37 family. http://togogenome.org/gene/110368:LOC112046555 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1G6 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/110368:LOC112047269 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4U4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits. http://togogenome.org/gene/110368:LOC112050044 ^@ http://purl.uniprot.org/uniprot/A0A6J1NG40 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/110368:LOC112057845 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8M5|||http://purl.uniprot.org/uniprot/A0A6J1P8N0|||http://purl.uniprot.org/uniprot/A0A6J1P8N9|||http://purl.uniprot.org/uniprot/A0A6J1P8X0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. http://togogenome.org/gene/110368:LOC112047433 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXN2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/110368:LOC112043663 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPX1 ^@ Similarity ^@ Belongs to the RRM elav family. http://togogenome.org/gene/110368:LOC112051173 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM76 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049339 ^@ http://purl.uniprot.org/uniprot/A0A6J1NII1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the X(+)/potassium ATPases subunit beta family.|||Cell membrane http://togogenome.org/gene/110368:LOC112053232 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKT8 ^@ Subcellular Location Annotation ^@ cilium http://togogenome.org/gene/110368:LOC112048691 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM21 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112055598 ^@ http://purl.uniprot.org/uniprot/A0A6J1P295 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/110368:LOC112058303 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112045763 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQE1|||http://purl.uniprot.org/uniprot/A0A6J1MTI0|||http://purl.uniprot.org/uniprot/A0A6J1MTI6|||http://purl.uniprot.org/uniprot/A0A6J1MYD2 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/110368:LOC112045177 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112052391 ^@ http://purl.uniprot.org/uniprot/A0A6J1NV14 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/110368:LOC112057916 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8W7 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/110368:LOC112044693 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|||Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/110368:LOC112053989 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus http://togogenome.org/gene/110368:LOC112045063 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112051576 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the translin family.|||DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.|||Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.|||Nucleus|||Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring. http://togogenome.org/gene/110368:LOC112055146 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2X4 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/110368:LOC112048090 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/110368:LOC112049974 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMTOR1 family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/110368:LOC112044540 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB1 family.|||Nucleus http://togogenome.org/gene/110368:LOC112046338 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSY8 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/110368:LOC112058309 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAV4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112053576 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVJ9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/110368:LOC112048117 ^@ http://purl.uniprot.org/uniprot/A0A6J1N305 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/110368:LOC112046752 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8C4 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. http://togogenome.org/gene/110368:LOC112048829 ^@ http://purl.uniprot.org/uniprot/A0A6J1N335 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112043922 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXT3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/110368:LOC112044841 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAUS3 family.|||spindle http://togogenome.org/gene/110368:LOC112053868 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112047783 ^@ http://purl.uniprot.org/uniprot/A0A6J1MYZ5 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/110368:LOC112058119 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9V4 ^@ Similarity ^@ Belongs to the beclin family. http://togogenome.org/gene/110368:LOC112046743 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2C8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS5 subunit family.|||Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112050394 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBY7|||http://purl.uniprot.org/uniprot/A0A6J1NHG9|||http://purl.uniprot.org/uniprot/A0A6J1NHH1|||http://purl.uniprot.org/uniprot/A0A6J1NMN8 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/110368:LOC112043082 ^@ http://purl.uniprot.org/uniprot/A0A6J1MG40 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049127 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCF2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112048520 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4L5 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/110368:LOC112043719 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWW7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily. http://togogenome.org/gene/110368:LOC112058254 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAA3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily. http://togogenome.org/gene/110368:LOC112043485 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP63 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/110368:LOC112058326 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAF6|||http://purl.uniprot.org/uniprot/A0A6J1PAF9|||http://purl.uniprot.org/uniprot/A0A6J1PAZ7|||http://purl.uniprot.org/uniprot/A0A6J1PB02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCF/LEF family.|||Nucleus http://togogenome.org/gene/110368:LOC112052813 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRP2 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/110368:LOC112053910 ^@ http://purl.uniprot.org/uniprot/A0A6J1P067 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112052913 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJK0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112052292 ^@ http://purl.uniprot.org/uniprot/A0A6J1NUP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112043734 ^@ http://purl.uniprot.org/uniprot/A0A6J1MI78|||http://purl.uniprot.org/uniprot/A0A6J1MI82|||http://purl.uniprot.org/uniprot/A0A6J1MKW0|||http://purl.uniprot.org/uniprot/A0A6J1MQ83|||http://purl.uniprot.org/uniprot/A0A6J1MWY7 ^@ Similarity ^@ Belongs to the SARM1 family. http://togogenome.org/gene/110368:LOC112044765 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUC7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112051579 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM38 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112049210 ^@ http://purl.uniprot.org/uniprot/A0A6J1N4I4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/110368:LOC112053044 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the malectin family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/110368:LOC112044939 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUT7 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/110368:LOC112053478 ^@ http://purl.uniprot.org/uniprot/A0A6J1NYW3 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Membrane|||Mitochondrion inner membrane|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/110368:LOC112057848 ^@ http://purl.uniprot.org/uniprot/A0A6J1P8K4|||http://purl.uniprot.org/uniprot/A0A6J1P8P4 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/110368:LOC112044239 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJX7 ^@ Similarity ^@ Belongs to the complex I NDUFB6 subunit family. http://togogenome.org/gene/110368:LOC112044927 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUS2 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/110368:LOC112058511 ^@ http://purl.uniprot.org/uniprot/A0A6J1PBE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/110368:LOC112054173 ^@ http://purl.uniprot.org/uniprot/A0A6J1P0X0 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/110368:LOC112048612 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112043862 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112047362 ^@ http://purl.uniprot.org/uniprot/A0A6J1NB25 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/110368:LOC112043762 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112051808 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMY0 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Rab family. http://togogenome.org/gene/110368:LOC112053858 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNB4|||http://purl.uniprot.org/uniprot/A0A6J1NQW8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112049511 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE05 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/110368:LOC112058012 ^@ http://purl.uniprot.org/uniprot/A0A6J1P999 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane http://togogenome.org/gene/110368:LOC112054584 ^@ http://purl.uniprot.org/uniprot/A0A6J1NZE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043523 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/110368:LOC112058082 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9Q5|||http://purl.uniprot.org/uniprot/A0A6J1P9Z0 ^@ Similarity ^@ In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.|||In the N-terminal section; belongs to the glutamate 5-kinase family. http://togogenome.org/gene/110368:LOC112045401 ^@ http://purl.uniprot.org/uniprot/A0A6J1N376 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/110368:LOC112047547 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY03 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/110368:LOC112044830 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUM6 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/110368:LOC112044014 ^@ http://purl.uniprot.org/uniprot/A0A6J1MY72 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112044547 ^@ http://purl.uniprot.org/uniprot/A0A6J1N029 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/110368:LOC112054591 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/110368:LOC112046108 ^@ http://purl.uniprot.org/uniprot/A0A6J1MRX2|||http://purl.uniprot.org/uniprot/A0A6J1N5X0 ^@ Similarity ^@ Belongs to the ZFTRAF1 family. http://togogenome.org/gene/110368:LOC112046248 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Secreted http://togogenome.org/gene/110368:LOC112050869 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJ30 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/110368:LOC112045532 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPK8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Secreted http://togogenome.org/gene/110368:LOC112046956 ^@ http://purl.uniprot.org/uniprot/A0A6J1N383 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/110368:LOC112053055 ^@ http://purl.uniprot.org/uniprot/A0A6J1NME3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112049532 ^@ http://purl.uniprot.org/uniprot/A0A6J1NE01 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/110368:LOC112051366 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLE2 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/110368:LOC112044515 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNT3 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/110368:LOC112051971 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNY7 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112050600 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.|||cytoskeleton http://togogenome.org/gene/110368:LOC112050091 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLI8 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/110368:LOC112048478 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1Q2 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/110368:LOC112049992 ^@ http://purl.uniprot.org/uniprot/A0A6J1NFX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/110368:LOC112057673 ^@ http://purl.uniprot.org/uniprot/A0A6J1P7Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the translin family.|||Nucleus http://togogenome.org/gene/110368:LOC112051108 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK41|||http://purl.uniprot.org/uniprot/A0A6J1NKA1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112054572 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTV1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112058259 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA93 ^@ Similarity ^@ Belongs to the Iojap/RsfS family. http://togogenome.org/gene/110368:LOC112047401 ^@ http://purl.uniprot.org/uniprot/A0A6J1MXJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the akirin family.|||Nucleus http://togogenome.org/gene/110368:LOC112046958 ^@ http://purl.uniprot.org/uniprot/A0A6J1N388 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/110368:LOC112046216 ^@ http://purl.uniprot.org/uniprot/A0A6J1MVI6 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/110368:LOC112043555 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/110368:LOC112046289 ^@ http://purl.uniprot.org/uniprot/A0A6J1MSQ6 ^@ Similarity ^@ Belongs to the IPP transferase family. http://togogenome.org/gene/110368:LOC112053005 ^@ http://purl.uniprot.org/uniprot/A0A6J1NM80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/110368:LOC112044586 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP14|||http://purl.uniprot.org/uniprot/A0A6J1N071 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112055838 ^@ http://purl.uniprot.org/uniprot/A0A6J1NW51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.|||Cell membrane http://togogenome.org/gene/110368:LOC112046336 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0T9 ^@ Similarity ^@ Belongs to the protease inhibitor I35 (TIMP) family. http://togogenome.org/gene/110368:LOC112043600 ^@ http://purl.uniprot.org/uniprot/A0A6J1MPP8 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/110368:LOC112056204 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2R7|||http://purl.uniprot.org/uniprot/A0A6J1P3P0|||http://purl.uniprot.org/uniprot/A0A6J1P4B9|||http://purl.uniprot.org/uniprot/A0A6J1P4C5 ^@ Similarity ^@ Belongs to the filamin family. http://togogenome.org/gene/110368:LOC112050643 ^@ http://purl.uniprot.org/uniprot/A0A6J1NAE3 ^@ Similarity ^@ Belongs to the PTEN phosphatase protein family. http://togogenome.org/gene/110368:LOC112048369 ^@ http://purl.uniprot.org/uniprot/A0A6J1N425|||http://purl.uniprot.org/uniprot/A0A6J1N9F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/110368:LOC112053693 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVY6 ^@ Similarity ^@ Belongs to the LDB family. http://togogenome.org/gene/110368:LOC112048259 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112049690 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/110368:LOC112043519 ^@ http://purl.uniprot.org/uniprot/A0A6J1MW88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Monomer. Component of the ribosomal small subunit (SSU) processome.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Binds to RNA. Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development.|||nucleolus http://togogenome.org/gene/110368:LOC112045186 ^@ http://purl.uniprot.org/uniprot/A0A6J1N2C6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/110368:LOC112050852 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIZ6 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112049553 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8P8 ^@ Similarity ^@ Belongs to the complexin/synaphin family. http://togogenome.org/gene/110368:LOC112045375 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/110368:LOC112048497 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1R7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/110368:LOC112051369 ^@ http://purl.uniprot.org/uniprot/A0A6J1NL76|||http://purl.uniprot.org/uniprot/A0A6J1NR76 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112043409 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.|||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. http://togogenome.org/gene/110368:LOC112054807 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS29|||http://purl.uniprot.org/uniprot/A0A6J1NUS4|||http://purl.uniprot.org/uniprot/A0A6J1NYW8|||http://purl.uniprot.org/uniprot/A0A6J1P059|||http://purl.uniprot.org/uniprot/A0A6J1P284|||http://purl.uniprot.org/uniprot/A0A6J1P293 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/110368:LOC112043483 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP58|||http://purl.uniprot.org/uniprot/A0A6J1MW12 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/110368:LOC112049201 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCN6 ^@ Similarity ^@ Belongs to the caprin family. http://togogenome.org/gene/110368:LOC112044916 ^@ http://purl.uniprot.org/uniprot/A0A6J1N1G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||extracellular space http://togogenome.org/gene/110368:LOC112045067 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calreticulin family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/110368:LOC112043424 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNW8 ^@ Function|||Similarity ^@ Belongs to the cytochrome c oxidase subunit 6B.|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. http://togogenome.org/gene/110368:LOC112046109 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DAD/OST2 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/110368:LOC112051171 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112043711 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQ40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112056710 ^@ http://purl.uniprot.org/uniprot/A0A6J1P573 ^@ Similarity ^@ Belongs to the FAM161 family. http://togogenome.org/gene/110368:LOC112044380 ^@ http://purl.uniprot.org/uniprot/A0A6J1MN85 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.|||Nucleus http://togogenome.org/gene/110368:LOC112056248 ^@ http://purl.uniprot.org/uniprot/A0A6J1P3N6 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/110368:LOC112049432 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDK4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/110368:LOC112051839 ^@ http://purl.uniprot.org/uniprot/A0A6J1NF78 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/110368:LOC112051852 ^@ http://purl.uniprot.org/uniprot/A0A6J1NHK6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112044484 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZV3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/110368:LOC112052988 ^@ http://purl.uniprot.org/uniprot/A0A6J1NJS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM TET family.|||Nucleus http://togogenome.org/gene/110368:LOC112056758 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5D6 ^@ Similarity ^@ Belongs to the ubiquitin family. http://togogenome.org/gene/110368:LOC112047263 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWY9|||http://purl.uniprot.org/uniprot/A0A6J1MZT0|||http://purl.uniprot.org/uniprot/A0A6J1N4T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112050774 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/110368:LOC112049440 ^@ http://purl.uniprot.org/uniprot/A0A6J1NDL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family.|||Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.|||Homodimer. The active form is probably a hexamer composed of 3 homodimers. http://togogenome.org/gene/110368:LOC112047813 ^@ http://purl.uniprot.org/uniprot/A0A6J1MZ43|||http://purl.uniprot.org/uniprot/A0A6J1N737|||http://purl.uniprot.org/uniprot/A0A6J1NCQ9 ^@ Similarity ^@ Belongs to the vinculin/alpha-catenin family. http://togogenome.org/gene/110368:LOC112053066 ^@ http://purl.uniprot.org/uniprot/A0A6J1NMF9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112053813 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNUT3 family.|||May play a role in mRNA splicing.|||Nucleus|||Part of a tri-snRNP complex. http://togogenome.org/gene/110368:LOC112044532 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKY2|||http://purl.uniprot.org/uniprot/A0A6J1MNV3|||http://purl.uniprot.org/uniprot/A0A6J1N015 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/110368:LOC112055680 ^@ http://purl.uniprot.org/uniprot/A0A6J1NY81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/110368:LOC112046290 ^@ http://purl.uniprot.org/uniprot/A0A6J1N0H6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/110368:LOC112045442 ^@ http://purl.uniprot.org/uniprot/A0A6J1MP95|||http://purl.uniprot.org/uniprot/A0A6J1MS84 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/110368:LOC112058273 ^@ http://purl.uniprot.org/uniprot/A0A6J1PA78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFS-II family.|||Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.|||Nucleus http://togogenome.org/gene/110368:LOC112053163 ^@ http://purl.uniprot.org/uniprot/A0A6J1NKH3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the myo-inositol oxygenase family.|||Binds 2 iron ions per subunit.|||Cytoplasm http://togogenome.org/gene/110368:LOC112047010 ^@ http://purl.uniprot.org/uniprot/A0A6J1N3W1 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/110368:LOC112054005 ^@ http://purl.uniprot.org/uniprot/A0A6J1NRH7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/110368:LOC112048359 ^@ http://purl.uniprot.org/uniprot/A0A6J1NES8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/110368:LOC112045037 ^@ http://purl.uniprot.org/uniprot/A0A6J1MQV0|||http://purl.uniprot.org/uniprot/A0A6J1MVG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.|||Peroxisome membrane http://togogenome.org/gene/110368:LOC112044850 ^@ http://purl.uniprot.org/uniprot/A0A6J1MM48 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112051673 ^@ http://purl.uniprot.org/uniprot/A0A6J1NEM4|||http://purl.uniprot.org/uniprot/A0A6J1NEP5|||http://purl.uniprot.org/uniprot/A0A6J1NGX2|||http://purl.uniprot.org/uniprot/A0A6J1NGX6|||http://purl.uniprot.org/uniprot/A0A6J1NGY1|||http://purl.uniprot.org/uniprot/A0A6J1NMG9|||http://purl.uniprot.org/uniprot/A0A6J1NMH6|||http://purl.uniprot.org/uniprot/A0A6J1NMM6|||http://purl.uniprot.org/uniprot/A0A6J1NMN0|||http://purl.uniprot.org/uniprot/A0A6J1NMN6|||http://purl.uniprot.org/uniprot/A0A6J1NMP7|||http://purl.uniprot.org/uniprot/A0A6J1NSE9|||http://purl.uniprot.org/uniprot/A0A6J1NSF5|||http://purl.uniprot.org/uniprot/A0A6J1NSG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112045984 ^@ http://purl.uniprot.org/uniprot/A0A6J1N5F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/110368:LOC112044451 ^@ http://purl.uniprot.org/uniprot/A0A6J1MNG4 ^@ Similarity ^@ Belongs to the replication factor A protein 2 family. http://togogenome.org/gene/110368:LOC112058322 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAI0|||http://purl.uniprot.org/uniprot/A0A6J1PAK5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/110368:LOC112053531 ^@ http://purl.uniprot.org/uniprot/A0A6J1NLV9|||http://purl.uniprot.org/uniprot/A0A6J1NZ24 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/110368:LOC112050558 ^@ http://purl.uniprot.org/uniprot/A0A6J1NN67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane http://togogenome.org/gene/110368:LOC112055822 ^@ http://purl.uniprot.org/uniprot/A0A6J1NVU9|||http://purl.uniprot.org/uniprot/A0A6J1P407 ^@ Similarity ^@ Belongs to the CHFR family. http://togogenome.org/gene/110368:LOC112051800 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NTAQ1 family.|||Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.|||Monomer. http://togogenome.org/gene/110368:LOC112054894 ^@ http://purl.uniprot.org/uniprot/A0A6J1NSB4|||http://purl.uniprot.org/uniprot/A0A6J1NV51 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112056187 ^@ http://purl.uniprot.org/uniprot/A0A6J1P2L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112058091 ^@ http://purl.uniprot.org/uniprot/A0A6J1P9N4 ^@ Function ^@ Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. http://togogenome.org/gene/110368:LOC112054488 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Clp1 family. Clp1 subfamily.|||Nucleus|||Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation. http://togogenome.org/gene/110368:LOC112043114 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMY5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/110368:LOC112046856 ^@ http://purl.uniprot.org/uniprot/A0A6J1MUU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Nucleus http://togogenome.org/gene/110368:LOC112043710 ^@ http://purl.uniprot.org/uniprot/A0A6J1MWV5 ^@ Similarity ^@ Belongs to the BORA family. http://togogenome.org/gene/110368:LOC112057701 ^@ http://purl.uniprot.org/uniprot/A0A6J1P837 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112054236 ^@ http://purl.uniprot.org/uniprot/A0A6J1NPU5 ^@ Similarity ^@ Belongs to the endosulfine family. http://togogenome.org/gene/110368:LOC112044282 ^@ http://purl.uniprot.org/uniprot/A0A6J1MK40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/110368:LOC112054027 ^@ http://purl.uniprot.org/uniprot/A0A6J1NNZ6 ^@ Similarity ^@ Belongs to the MFAP1 family. http://togogenome.org/gene/110368:LOC112043930 ^@ http://purl.uniprot.org/uniprot/A0A6J1MR88 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/110368:LOC112053214 ^@ http://purl.uniprot.org/uniprot/A0A6J1NU36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUB family.|||Cytoplasm http://togogenome.org/gene/110368:LOC112044606 ^@ http://purl.uniprot.org/uniprot/A0A6J1MTJ8 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/110368:LOC112056403 ^@ http://purl.uniprot.org/uniprot/A0A6J1P4G5 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I family. http://togogenome.org/gene/110368:LOC112055893 ^@ http://purl.uniprot.org/uniprot/A0A6J1P1V7 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/110368:LOC112044614 ^@ http://purl.uniprot.org/uniprot/A0A6J1ML62 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/110368:LOC112049139 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCF4|||http://purl.uniprot.org/uniprot/A0A6J1NCH0|||http://purl.uniprot.org/uniprot/A0A6J1NHV7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/110368:LOC112052998 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RBM8A family.|||Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.|||Cytoplasm|||Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.|||Nucleus|||Nucleus speckle http://togogenome.org/gene/110368:LOC112050317 ^@ http://purl.uniprot.org/uniprot/A0A6J1NH85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quiver family.|||Cell membrane|||Membrane|||Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability. http://togogenome.org/gene/110368:LOC112043406 ^@ http://purl.uniprot.org/uniprot/A0A6J1MJM3 ^@ Function|||Subunit ^@ Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.|||Self-associates forming complexes of several hundred monomers. http://togogenome.org/gene/110368:LOC112050344 ^@ http://purl.uniprot.org/uniprot/A0A6J1NBS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS3 family.|||Mitochondrion http://togogenome.org/gene/110368:LOC112044212 ^@ http://purl.uniprot.org/uniprot/A0A6J1MS64 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/110368:LOC112056902 ^@ http://purl.uniprot.org/uniprot/A0A6J1P5T2 ^@ Similarity ^@ Belongs to the CFAP144 family. http://togogenome.org/gene/110368:LOC112058380 ^@ http://purl.uniprot.org/uniprot/A0A6J1PAQ6 ^@ Similarity ^@ Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. http://togogenome.org/gene/110368:LOC112050443 ^@ http://purl.uniprot.org/uniprot/A0A6J1N9S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/110368:LOC112044536 ^@ http://purl.uniprot.org/uniprot/A0A6J1MKY6 ^@ Function ^@ May be a negative regulator of NF-kappa-B and p53-mediated gene transcription. http://togogenome.org/gene/110368:LOC112044899 ^@ http://purl.uniprot.org/uniprot/A0A6J1MMA0|||http://purl.uniprot.org/uniprot/A0A6J1MUX9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/110368:LOC112052468 ^@ http://purl.uniprot.org/uniprot/A0A6J1NK71 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/110368:LOC112048233 ^@ http://purl.uniprot.org/uniprot/A0A6J1N8P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/110368:LOC112051323 ^@ http://purl.uniprot.org/uniprot/A0A6J1ND38 ^@ Similarity ^@ Belongs to the DPCD family. http://togogenome.org/gene/110368:LOC112052958 ^@ http://purl.uniprot.org/uniprot/A0A6J1NS56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/110368:LOC112047871 ^@ http://purl.uniprot.org/uniprot/A0A1C9EGL6|||http://purl.uniprot.org/uniprot/A0A6J1N7A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Membrane http://togogenome.org/gene/110368:LOC112042870 ^@ http://purl.uniprot.org/uniprot/A0A6J1MLL6 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus speckle http://togogenome.org/gene/110368:LOC112056185 ^@ http://purl.uniprot.org/uniprot/A0A6J1P044|||http://purl.uniprot.org/uniprot/A0A6J1P2K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/110368:LOC112053959 ^@ http://purl.uniprot.org/uniprot/A0A6J1NX88 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS10 family. http://togogenome.org/gene/110368:LOC112055147 ^@ http://purl.uniprot.org/uniprot/A0A6J1NTA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/110368:LOC112052162 ^@ http://purl.uniprot.org/uniprot/A0A6J1NIZ3|||http://purl.uniprot.org/uniprot/A0A6J1NPS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/110368:LOC112047769 ^@ http://purl.uniprot.org/uniprot/A0A6J1NCK3 ^@ Similarity ^@ Belongs to the pyruvate kinase family.