http://togogenome.org/gene/1109412:AWC36_RS23160 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS18580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS21435 ^@ http://purl.uniprot.org/uniprot/A0A250BJY2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1109412:AWC36_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A250BLS1 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/1109412:AWC36_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWH5 ^@ Function|||Similarity ^@ Belongs to the bacterial-type ferredoxin family. FixX subfamily.|||Could be a 3Fe-4S cluster-containing protein. http://togogenome.org/gene/1109412:AWC36_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1F5 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/1109412:AWC36_RS17560 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1109412:AWC36_RS22905 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVZ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A250BBW4 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1109412:AWC36_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZZ2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/1109412:AWC36_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV00 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1109412:AWC36_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0V2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPZ4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1109412:AWC36_RS12405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A250BL41 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/1109412:AWC36_RS21420 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS21450 ^@ http://purl.uniprot.org/uniprot/A0A250BJG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/1109412:AWC36_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A0G4K385 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/1109412:AWC36_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1109412:AWC36_RS12165 ^@ http://purl.uniprot.org/uniprot/A0A250BFU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. http://togogenome.org/gene/1109412:AWC36_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSN3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1109412:AWC36_RS20815 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ38 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1109412:AWC36_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A250BL66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0C2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSP3 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1109412:AWC36_RS20770 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.|||Cell membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/1109412:AWC36_RS20640 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU79 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1109412:AWC36_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A250B9I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/1109412:AWC36_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A0G4K133 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21240 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12090 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1109412:AWC36_RS20860 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A250BHR3 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1109412:AWC36_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS18040 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT86 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15045 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR15 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1109412:AWC36_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWN4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1109412:AWC36_RS21430 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1109412:AWC36_RS20150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ12 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/1109412:AWC36_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0S4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1109412:AWC36_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0G8 ^@ Similarity ^@ Belongs to the NifZ family. http://togogenome.org/gene/1109412:AWC36_RS18790 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1109412:AWC36_RS22345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV60 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein. http://togogenome.org/gene/1109412:AWC36_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQN0 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1109412:AWC36_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A250BI62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS03060 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYB2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1109412:AWC36_RS18825 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1109412:AWC36_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1109412:AWC36_RS20235 ^@ http://purl.uniprot.org/uniprot/A0A250BIV0 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1109412:AWC36_RS17715 ^@ http://purl.uniprot.org/uniprot/A0A250BIN1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZF2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1109412:AWC36_RS21750 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/1109412:AWC36_RS17590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS23175 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI6 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1109412:AWC36_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2D1 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1109412:AWC36_RS18290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYP6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese.|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS59 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1109412:AWC36_RS18850 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.|||Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS18840 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/1109412:AWC36_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSZ4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1109412:AWC36_RS21305 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUP0 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/1109412:AWC36_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPM2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYF9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1109412:AWC36_RS00785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW96 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQL9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1109412:AWC36_RS13275 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ80 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1109412:AWC36_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZW1 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1109412:AWC36_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXT2 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1109412:AWC36_RS23610 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVU3 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1109412:AWC36_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS42 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1109412:AWC36_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1A3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPM8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1109412:AWC36_RS21460 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS20400 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUM3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1109412:AWC36_RS17745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/1109412:AWC36_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQE1 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A250BHW2 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1109412:AWC36_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUK8 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1109412:AWC36_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20895 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1109412:AWC36_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWI0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRE3 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1109412:AWC36_RS21675 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the rhamnose mutarotase family.|||Cytoplasm|||Homodimer.|||Involved in the anomeric conversion of L-rhamnose. http://togogenome.org/gene/1109412:AWC36_RS22815 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A0G4K096 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1109412:AWC36_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A250BDV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1109412:AWC36_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXH8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13950 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS12655 ^@ http://purl.uniprot.org/uniprot/A0A250BFA7 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1109412:AWC36_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A250BC93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C40 family.|||Nucleus http://togogenome.org/gene/1109412:AWC36_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2I5 ^@ Similarity ^@ Belongs to the SIP oxidoreductase family. http://togogenome.org/gene/1109412:AWC36_RS17335 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSB8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRC3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1109412:AWC36_RS15095 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20205 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1109412:AWC36_RS20485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU85 ^@ Function|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. http://togogenome.org/gene/1109412:AWC36_RS21410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS23230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVH2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1109412:AWC36_RS17040 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS37 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWE6 ^@ Function|||Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family.|||CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. http://togogenome.org/gene/1109412:AWC36_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1109412:AWC36_RS18530 ^@ http://purl.uniprot.org/uniprot/A0A250BI71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1109412:AWC36_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXZ8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A0G4K190 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2Z3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21535 ^@ http://purl.uniprot.org/uniprot/A0A250BJW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1109412:AWC36_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS21045 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS13360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPX6 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1109412:AWC36_RS17145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A250BAA7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A250BL83 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/1109412:AWC36_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A250BDJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M23B family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A250BJH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1J5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1109412:AWC36_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A0G4K169 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0S6 ^@ Similarity ^@ Belongs to the UPF0263 family. http://togogenome.org/gene/1109412:AWC36_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU42 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1109412:AWC36_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A0G4K209 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVD3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1109412:AWC36_RS22395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV68 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1109412:AWC36_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS22780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV87 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1109412:AWC36_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A250BF25 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1109412:AWC36_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS22455 ^@ http://purl.uniprot.org/uniprot/A0A250BJX8 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/1109412:AWC36_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPL7 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS17830 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.|||Cell inner membrane|||Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.|||Homodimer.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20165 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A250BA55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. Interacts with IscU. http://togogenome.org/gene/1109412:AWC36_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX63 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase 20 family.|||Homotetramer.|||Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. http://togogenome.org/gene/1109412:AWC36_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0G4K030 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/1109412:AWC36_RS16705 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1109412:AWC36_RS17735 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSI8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1109412:AWC36_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21440 ^@ http://purl.uniprot.org/uniprot/A0A250BJX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1109412:AWC36_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0L1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Binds two Mg(2+) per subunit.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1109412:AWC36_RS17995 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A250BCV3 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/1109412:AWC36_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2G2 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/1109412:AWC36_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS71 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1109412:AWC36_RS20375 ^@ http://purl.uniprot.org/uniprot/A0A250BIW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0P8 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/1109412:AWC36_RS12055 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP64 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS20825 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1109412:AWC36_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX19 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1109412:AWC36_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPP4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1109412:AWC36_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1D6 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS14900 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14350 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR49 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A250BEJ1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1109412:AWC36_RS20105 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS19155 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU07 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1109412:AWC36_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZG6 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1109412:AWC36_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXG1 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/1109412:AWC36_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A250BLI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1109412:AWC36_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A0G4K109 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS87 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/1109412:AWC36_RS22490 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV88 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.|||Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A250BGJ3 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ46 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/1109412:AWC36_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS00 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1109412:AWC36_RS14480 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQK8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1109412:AWC36_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20100 ^@ http://purl.uniprot.org/uniprot/A0A250BLY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1109412:AWC36_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A250BHJ3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1109412:AWC36_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1S0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/1109412:AWC36_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0N5 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS20450 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/1109412:AWC36_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1109412:AWC36_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYF1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1109412:AWC36_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS06 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1109412:AWC36_RS19990 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTS9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A250BLT9 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1109412:AWC36_RS17755 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/1109412:AWC36_RS21200 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUM7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DamX family.|||Cell inner membrane|||Non-essential cell division protein.|||The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring. http://togogenome.org/gene/1109412:AWC36_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPB9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1109412:AWC36_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0U9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1109412:AWC36_RS14115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1109412:AWC36_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A250BDU0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWG2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1109412:AWC36_RS20440 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1109412:AWC36_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYG1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A250BDZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS17375 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWE7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS20195 ^@ http://purl.uniprot.org/uniprot/A0A250BIU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1109412:AWC36_RS16535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/1109412:AWC36_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A0G4K170 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1109412:AWC36_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS11910 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPM5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS21705 ^@ http://purl.uniprot.org/uniprot/A0A250BLQ6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Activates expression of the rhaSR operon in response to L-rhamnose.|||Binds DNA as a dimer.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/1109412:AWC36_RS22520 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPP1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1109412:AWC36_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1109412:AWC36_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SufE family.|||Cytoplasm|||Homodimer. Interacts with SufS.|||Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process. http://togogenome.org/gene/1109412:AWC36_RS22790 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVW8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1109412:AWC36_RS20880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUG0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS19980 ^@ http://purl.uniprot.org/uniprot/A0A250BJ38 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1109412:AWC36_RS23325 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecM family.|||Periplasm|||Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.|||cytosol http://togogenome.org/gene/1109412:AWC36_RS20050 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTU5 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. KdkA/rfaP family.|||Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. http://togogenome.org/gene/1109412:AWC36_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0A3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1109412:AWC36_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1R1 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/1109412:AWC36_RS22445 ^@ http://purl.uniprot.org/uniprot/A0A250BLK0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SprT family.|||Binds 1 zinc ion.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A250BA08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0S3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TonB family.|||Cell inner membrane|||Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1109412:AWC36_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A0G4K004 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1109412:AWC36_RS13670 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ01 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS16875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS03 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1109412:AWC36_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY49 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/1109412:AWC36_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1109412:AWC36_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWQ6 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1109412:AWC36_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWX4 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1109412:AWC36_RS18760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTZ4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS17135 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0W6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/1109412:AWC36_RS18820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1109412:AWC36_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukF family.|||Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.|||nucleoid http://togogenome.org/gene/1109412:AWC36_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/1109412:AWC36_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0R2 ^@ Similarity ^@ Belongs to the CmpA/NrtA family. http://togogenome.org/gene/1109412:AWC36_RS16550 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRU1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1109412:AWC36_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWJ7 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1109412:AWC36_RS18505 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22885 ^@ http://purl.uniprot.org/uniprot/A0A250BKI8 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1109412:AWC36_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1109412:AWC36_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A0G4K014 ^@ Function|||Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.|||Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS20540 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/1109412:AWC36_RS12040 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP49 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1109412:AWC36_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2G8 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A250BH39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1109412:AWC36_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPS0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1109412:AWC36_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A0G4K108 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1109412:AWC36_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A0G4K3G2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS16315 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYI9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1109412:AWC36_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWL5 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1109412:AWC36_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/1109412:AWC36_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1109412:AWC36_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1109412:AWC36_RS23305 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1109412:AWC36_RS15865 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS16595 ^@ http://purl.uniprot.org/uniprot/A0A250BH18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS18000 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/1109412:AWC36_RS17750 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/1109412:AWC36_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1E8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1109412:AWC36_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Z6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWS8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTZ3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1109412:AWC36_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A0G4K204 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1109412:AWC36_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1109412:AWC36_RS19360 ^@ http://purl.uniprot.org/uniprot/A0A250BIE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0W7 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1109412:AWC36_RS17245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS73 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/1109412:AWC36_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A250BC15 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS16860 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/1109412:AWC36_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0E4 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/1109412:AWC36_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWM1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1109412:AWC36_RS12000 ^@ http://purl.uniprot.org/uniprot/A0A250BER5 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13870 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPH9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1109412:AWC36_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZC7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1109412:AWC36_RS21370 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrF/TusC family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/1109412:AWC36_RS14165 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSD9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPG1 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1109412:AWC36_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.|||Belongs to the RseA family.|||Cell inner membrane|||Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB. http://togogenome.org/gene/1109412:AWC36_RS21710 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUW3 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1109412:AWC36_RS17475 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSA4 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1109412:AWC36_RS20005 ^@ http://purl.uniprot.org/uniprot/A0A250BIQ3 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/1109412:AWC36_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZA1 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS13185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Q5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose.|||Homohexamer. http://togogenome.org/gene/1109412:AWC36_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A250B9C4 ^@ Function|||Subunit ^@ Hexamer of two alpha, two beta, and two delta chains.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein. http://togogenome.org/gene/1109412:AWC36_RS20745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUA7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS20080 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTY5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/1109412:AWC36_RS22880 ^@ http://purl.uniprot.org/uniprot/A0A250BKM9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1109412:AWC36_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A250BC90 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1109412:AWC36_RS21195 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUI3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0X3 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/1109412:AWC36_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS13905 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21490 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1109412:AWC36_RS17090 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS23335 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW91 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1109412:AWC36_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWM8 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1109412:AWC36_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0G4K289 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.|||Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.|||Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS23250 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1109412:AWC36_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ75 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1109412:AWC36_RS23270 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Z9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1K6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS62 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1109412:AWC36_RS16695 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRX3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1109412:AWC36_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPQ3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1109412:AWC36_RS21530 ^@ http://purl.uniprot.org/uniprot/A0A250BJH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1109412:AWC36_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS16935 ^@ http://purl.uniprot.org/uniprot/A0A250BHD3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family.|||Binds 2 Fe(2+) ions per subunit.|||Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. http://togogenome.org/gene/1109412:AWC36_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS21590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU6 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/1109412:AWC36_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0L0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1109412:AWC36_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A0G4K264 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS23280 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVK0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/1109412:AWC36_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/1109412:AWC36_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1P2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1109412:AWC36_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A250BG09 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/1109412:AWC36_RS21230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV94 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPB2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1109412:AWC36_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A250BCK3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1109412:AWC36_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZC5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/1109412:AWC36_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A250BL93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS11985 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/1109412:AWC36_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0F0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/1109412:AWC36_RS20700 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A250BL12 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1109412:AWC36_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A0G4K211 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS19115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1109412:AWC36_RS12030 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14630 ^@ http://purl.uniprot.org/uniprot/A0A250BGA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/1109412:AWC36_RS17085 ^@ http://purl.uniprot.org/uniprot/A0A250BHM9 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1109412:AWC36_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A250BD53 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1109412:AWC36_RS21700 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Activates expression of the rhaBAD and rhaT operons.|||Binds DNA as a dimer.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/1109412:AWC36_RS17895 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1109412:AWC36_RS14595 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQM6 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1109412:AWC36_RS18770 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A250BL77 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS13215 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPR0 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1109412:AWC36_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZX9 ^@ Function|||Similarity ^@ Belongs to the thiamine kinase family.|||Catalyzes the phosphorylation of thiamine to thiamine phosphate. http://togogenome.org/gene/1109412:AWC36_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX37 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1109412:AWC36_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A0G4K009 ^@ Function|||Subunit ^@ Homodimer.|||Required for resistance to the phenazine antibiotic. http://togogenome.org/gene/1109412:AWC36_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1B2 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.|||Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. http://togogenome.org/gene/1109412:AWC36_RS16925 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1109412:AWC36_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP51 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1109412:AWC36_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A250BG24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS15530 ^@ http://purl.uniprot.org/uniprot/A0A250BLH6 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/1109412:AWC36_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYK9 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWJ1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1109412:AWC36_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0P9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A250BGJ4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Homodimer.|||May be involved in cell division. http://togogenome.org/gene/1109412:AWC36_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS22500 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV91 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1109412:AWC36_RS21480 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1109412:AWC36_RS12885 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPJ9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1109412:AWC36_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWL4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/1109412:AWC36_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWY0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1109412:AWC36_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A250B9P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A250BGY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15980 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1109412:AWC36_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1109412:AWC36_RS14665 ^@ http://purl.uniprot.org/uniprot/A0A250BG30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1109412:AWC36_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS19985 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTW4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1109412:AWC36_RS17925 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSK5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS19840 ^@ http://purl.uniprot.org/uniprot/A0A250BJ11 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS16805 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS19925 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20140 ^@ http://purl.uniprot.org/uniprot/A0A250BLX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15090 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQY5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1109412:AWC36_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlE subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1109412:AWC36_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYE2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1109412:AWC36_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXA8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1109412:AWC36_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZD7 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1109412:AWC36_RS15655 ^@ http://purl.uniprot.org/uniprot/A0A250BH01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1109412:AWC36_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1109412:AWC36_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/1109412:AWC36_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX01 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1109412:AWC36_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A0G4K236 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS18555 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdD family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/1109412:AWC36_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXI4 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/1109412:AWC36_RS13290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPS5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1109412:AWC36_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A250BMF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21740 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUT8 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/1109412:AWC36_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1109412:AWC36_RS06875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZQ4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS10720 ^@ http://purl.uniprot.org/uniprot/A0A0G4K284 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSX0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1109412:AWC36_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS20680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUB7 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1109412:AWC36_RS13310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A250BDB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS21415 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1109412:AWC36_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS13325 ^@ http://purl.uniprot.org/uniprot/A0A250BFL6 ^@ Function|||Similarity ^@ Belongs to the AcpH family.|||Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP. http://togogenome.org/gene/1109412:AWC36_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP73 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTY2 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/1109412:AWC36_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWP7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1109412:AWC36_RS15925 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZF5 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1109412:AWC36_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWA4 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/1109412:AWC36_RS23030 ^@ http://purl.uniprot.org/uniprot/A0A250BLL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11505 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11620 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2Y2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1109412:AWC36_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Z8 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1109412:AWC36_RS22435 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZM1 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1109412:AWC36_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A250BGF7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1109412:AWC36_RS16635 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRV1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1109412:AWC36_RS16025 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRH4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CutA family.|||Binds 1 copper ion per subunit.|||Cytoplasm|||Homotrimer.|||Involved in resistance toward heavy metals. http://togogenome.org/gene/1109412:AWC36_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 9 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS15425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR56 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/1109412:AWC36_RS00745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/1109412:AWC36_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A250BBX8 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1109412:AWC36_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/1109412:AWC36_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Z3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/1109412:AWC36_RS22375 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVT3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS17710 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSI3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/1109412:AWC36_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1109412:AWC36_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1S4 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/1109412:AWC36_RS16020 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRH2 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/1109412:AWC36_RS19745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUC2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1109412:AWC36_RS20405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU39 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1109412:AWC36_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A250BDQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.|||Bacterial flagellum basal body|||Belongs to the YcgR family.|||Monomer. Interacts with the flagellar basal bodies. http://togogenome.org/gene/1109412:AWC36_RS15520 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS23240 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/1109412:AWC36_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU68 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/1109412:AWC36_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPD1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1109412:AWC36_RS19795 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS21080 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUG1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1109412:AWC36_RS16945 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSR4 ^@ Function|||Similarity|||Subunit ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS17780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSJ8 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1109412:AWC36_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWA6 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS13005 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPL2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS21085 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS19960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/1109412:AWC36_RS15645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1109412:AWC36_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZS4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPE2 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/1109412:AWC36_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1109412:AWC36_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXT8 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP85 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1109412:AWC36_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1109412:AWC36_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A250BLG7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1109412:AWC36_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRI6 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1109412:AWC36_RS12265 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/1109412:AWC36_RS12050 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/1109412:AWC36_RS23535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVQ3 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/1109412:AWC36_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A250BKX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS16355 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSF4 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1109412:AWC36_RS15340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR73 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1109412:AWC36_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A250BB45 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1109412:AWC36_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A0G4K070 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRC0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1109412:AWC36_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPU7 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1109412:AWC36_RS23310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1109412:AWC36_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRQ5 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1109412:AWC36_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. http://togogenome.org/gene/1109412:AWC36_RS21990 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQM9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS20325 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A250BDS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A250BIH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQH6 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily. http://togogenome.org/gene/1109412:AWC36_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSX2 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1109412:AWC36_RS23340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVQ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1109412:AWC36_RS21560 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS19885 ^@ http://purl.uniprot.org/uniprot/A0A250BJ58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0G4K266 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1109412:AWC36_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A0G4K127 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A250BEH3 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1109412:AWC36_RS22360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS16205 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS76 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/1109412:AWC36_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A250BHG5 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1109412:AWC36_RS19275 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU28 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A250BL27 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/1109412:AWC36_RS15540 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR79 ^@ Function|||Similarity ^@ Belongs to the UbiT family.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor. http://togogenome.org/gene/1109412:AWC36_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A250BL62 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1109412:AWC36_RS22875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVD0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1109412:AWC36_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY79 ^@ Function|||Similarity ^@ Belongs to the bacterial-type ferredoxin family. FixX subfamily.|||Could be a 3Fe-4S cluster-containing protein. http://togogenome.org/gene/1109412:AWC36_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A250BBY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS17415 ^@ http://purl.uniprot.org/uniprot/A0A250BHG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1109412:AWC36_RS23140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW56 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane|||The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB). http://togogenome.org/gene/1109412:AWC36_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1109412:AWC36_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ99 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1109412:AWC36_RS21580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUT7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1109412:AWC36_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1G5 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1109412:AWC36_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWJ2 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1109412:AWC36_RS16905 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1109412:AWC36_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPC5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS20985 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Q2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxT phosphotransferase family.|||Cell inner membrane|||Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS21495 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUS4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1109412:AWC36_RS16800 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0C7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1109412:AWC36_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSW3 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1109412:AWC36_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JST4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21525 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1109412:AWC36_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A250BCG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/1109412:AWC36_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWE8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS21390 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1C5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Component of a transport pathway that contributes to membrane integrity.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22860 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS19145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1109412:AWC36_RS09460 ^@ http://purl.uniprot.org/uniprot/A0A250BDV6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX75 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1109412:AWC36_RS19370 ^@ http://purl.uniprot.org/uniprot/A0A250BJH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21125 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUL3 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1109412:AWC36_RS12485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/1109412:AWC36_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the lipid A palmitoyltransferase family.|||Cell outer membrane|||Homodimer.|||Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors. http://togogenome.org/gene/1109412:AWC36_RS12565 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0370 family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS19560 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.|||Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A0G4K161 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP21 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1109412:AWC36_RS16850 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSP5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSB2 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS21765 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/1109412:AWC36_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXS9 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1109412:AWC36_RS21895 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUZ2 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family.|||This protein is a Fe-Mo-cofactor biosynthetic component. http://togogenome.org/gene/1109412:AWC36_RS20320 ^@ http://purl.uniprot.org/uniprot/A0A250BJ36 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0B9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS21500 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUP8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1109412:AWC36_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1109412:AWC36_RS21545 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUW9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1109412:AWC36_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPN2 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1109412:AWC36_RS21785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS15630 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1109412:AWC36_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZU7 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1109412:AWC36_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0G3 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1109412:AWC36_RS12400 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSA0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/1109412:AWC36_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPX3 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/1109412:AWC36_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVV9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.|||Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT24 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXQ3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2H4 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/1109412:AWC36_RS19185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTE1 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1109412:AWC36_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTP2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS18390 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSU4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11990 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP52 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/1109412:AWC36_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2C9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1109412:AWC36_RS17405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS94 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS18960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21455 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUS3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1109412:AWC36_RS14625 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQN1 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1109412:AWC36_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRA9 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1109412:AWC36_RS19180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU11 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1109412:AWC36_RS12465 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1M3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS20785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS20190 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPC6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ68 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/1109412:AWC36_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20125 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS16990 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/1109412:AWC36_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/1109412:AWC36_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS13220 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPR9 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1109412:AWC36_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXI2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1109412:AWC36_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11945 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HspQ family.|||Cytoplasm|||Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. http://togogenome.org/gene/1109412:AWC36_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWF2 ^@ Function|||Similarity ^@ Belongs to the ETF-QO/FixC family.|||Part of an electron transfer system. http://togogenome.org/gene/1109412:AWC36_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ89 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1109412:AWC36_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX79 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/1109412:AWC36_RS16660 ^@ http://purl.uniprot.org/uniprot/A0A250BHD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/1109412:AWC36_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXT4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXV4 ^@ Function|||Similarity ^@ Belongs to the IolE/MocC family.|||Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). http://togogenome.org/gene/1109412:AWC36_RS11595 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1109412:AWC36_RS19665 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1109412:AWC36_RS20380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23235 ^@ http://purl.uniprot.org/uniprot/A0A250BKQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AlaE exporter family.|||Cell inner membrane|||Exports L-alanine. http://togogenome.org/gene/1109412:AWC36_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYZ1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Membrane|||Monomer and homodimer.|||The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.|||With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. http://togogenome.org/gene/1109412:AWC36_RS20340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU13 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSF6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1109412:AWC36_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWE3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS19350 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTG4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW20 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1109412:AWC36_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A250BFT5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1109412:AWC36_RS22335 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV54 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22495 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV65 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS20750 ^@ http://purl.uniprot.org/uniprot/A0A250BK54 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Homotetramer.|||Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. http://togogenome.org/gene/1109412:AWC36_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWZ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0I6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1109412:AWC36_RS21735 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUW7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/1109412:AWC36_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Z3 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/1109412:AWC36_RS15245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR16 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWX0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1109412:AWC36_RS22845 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1109412:AWC36_RS22480 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A0G4K002 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWD7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/1109412:AWC36_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXE5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1109412:AWC36_RS20215 ^@ http://purl.uniprot.org/uniprot/A0A250BM00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/1109412:AWC36_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A0G4K149 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS15410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1109412:AWC36_RS20130 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU22 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/1109412:AWC36_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXQ5 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/1109412:AWC36_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX08 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/1109412:AWC36_RS21995 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1109412:AWC36_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A0G4K117 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1109412:AWC36_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1109412:AWC36_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A250BFK7 ^@ Function|||Similarity ^@ Belongs to the isochorismate synthase family.|||Catalyzes the conversion of chorismate to isochorismate. http://togogenome.org/gene/1109412:AWC36_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A250BCZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/1109412:AWC36_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWM2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1109412:AWC36_RS23300 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1109412:AWC36_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ34 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/1109412:AWC36_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1109412:AWC36_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A250BHZ8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX27 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1109412:AWC36_RS21600 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/1109412:AWC36_RS14325 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13130 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ54 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1109412:AWC36_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0D9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MzrA family.|||Cell inner membrane|||Interacts with EnvZ.|||Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. http://togogenome.org/gene/1109412:AWC36_RS20295 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUJ9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1109412:AWC36_RS14435 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQJ9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS21015 ^@ http://purl.uniprot.org/uniprot/A0A250BLH8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/1109412:AWC36_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1109412:AWC36_RS13640 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1109412:AWC36_RS16385 ^@ http://purl.uniprot.org/uniprot/A0A250BLB6 ^@ Similarity ^@ Belongs to the UPF0149 family. http://togogenome.org/gene/1109412:AWC36_RS21265 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVL7 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1109412:AWC36_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A0G4K324 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1H2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1109412:AWC36_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0K4 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1109412:AWC36_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1T5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1109412:AWC36_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A250B9Q8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Crl family.|||Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS22895 ^@ http://purl.uniprot.org/uniprot/A0A250BKC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1109412:AWC36_RS21760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUX2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD). http://togogenome.org/gene/1109412:AWC36_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUN6 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1109412:AWC36_RS13330 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPS6 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/1109412:AWC36_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0M7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1109412:AWC36_RS22470 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV61 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXR3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1109412:AWC36_RS08360 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Y0 ^@ Similarity ^@ Belongs to the KAE1 / TsaD family. TsaB subfamily. http://togogenome.org/gene/1109412:AWC36_RS11160 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWR0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1109412:AWC36_RS12180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP62 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1109412:AWC36_RS01840 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1109412:AWC36_RS19140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1109412:AWC36_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1R9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. http://togogenome.org/gene/1109412:AWC36_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A250BFA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1109412:AWC36_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A250BFK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR75 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/1109412:AWC36_RS11980 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPP0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1109412:AWC36_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS48 ^@ Similarity ^@ Belongs to the UPF0441 family. http://togogenome.org/gene/1109412:AWC36_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17075 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRF9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ18 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWB7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/1109412:AWC36_RS18190 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/1109412:AWC36_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQM0 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily. http://togogenome.org/gene/1109412:AWC36_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS22870 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVJ2 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1109412:AWC36_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12535 ^@ http://purl.uniprot.org/uniprot/A0A250BFG4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/1109412:AWC36_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A250B9U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1109412:AWC36_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||In the N-terminal section; belongs to the complex I 30 kDa subunit family.|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1109412:AWC36_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQN3 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1109412:AWC36_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWZ9 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family. http://togogenome.org/gene/1109412:AWC36_RS15475 ^@ http://purl.uniprot.org/uniprot/A0A250BGT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTR6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXB3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1109412:AWC36_RS23550 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVS6 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1109412:AWC36_RS23095 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVE1 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1109412:AWC36_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ05 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWN0 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/1109412:AWC36_RS19450 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPQ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A250BLU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine. http://togogenome.org/gene/1109412:AWC36_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ40 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1109412:AWC36_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU62 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/1109412:AWC36_RS14640 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQR9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Z0 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1109412:AWC36_RS09780 ^@ http://purl.uniprot.org/uniprot/A0A0G4K203 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1109412:AWC36_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWF6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/1109412:AWC36_RS15975 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRG2 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1109412:AWC36_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS19880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A0G4K183 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/1109412:AWC36_RS15885 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ62 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1109412:AWC36_RS12500 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1109412:AWC36_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPG5 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1109412:AWC36_RS19270 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS17785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSG0 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1109412:AWC36_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A250BBG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/1109412:AWC36_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX66 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/1109412:AWC36_RS21140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUL1 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1109412:AWC36_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0V7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS20850 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUD4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1109412:AWC36_RS20820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUC3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS20465 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family.|||Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS19150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1109412:AWC36_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A250BFI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17860 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0V6 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/1109412:AWC36_RS16310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P-Pant transferase superfamily. EntD family.|||EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.|||Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively. http://togogenome.org/gene/1109412:AWC36_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.|||Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS17620 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS12140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1109412:AWC36_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZX7 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1109412:AWC36_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1E4 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1109412:AWC36_RS18600 ^@ http://purl.uniprot.org/uniprot/A0A250BIE8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/1109412:AWC36_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A0G4K068 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0W3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1109412:AWC36_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS22945 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVC2 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1109412:AWC36_RS18120 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A250BA03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS12295 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPA3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPG3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1109412:AWC36_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A250BLS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Z4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhD family.|||Cytoplasm|||Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.|||The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA. http://togogenome.org/gene/1109412:AWC36_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX84 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.|||Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably phosphorylates lipids; the in vivo substrate is unknown. http://togogenome.org/gene/1109412:AWC36_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0T8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1109412:AWC36_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A250BAE6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1109412:AWC36_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXU6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1109412:AWC36_RS15815 ^@ http://purl.uniprot.org/uniprot/A0A250BH02 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1109412:AWC36_RS16870 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUA0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23010 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVL1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXL7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1109412:AWC36_RS20735 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1D1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPP7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1109412:AWC36_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0B7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRC7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1109412:AWC36_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1109412:AWC36_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/1109412:AWC36_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS15110 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRI8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS21445 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1109412:AWC36_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZE9 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/1109412:AWC36_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1109412:AWC36_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A250BL98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWG1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/1109412:AWC36_RS21770 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09110 ^@ http://purl.uniprot.org/uniprot/A0A250BDP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS18875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT63 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS17255 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS79 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1109412:AWC36_RS13695 ^@ http://purl.uniprot.org/uniprot/A0A250BG23 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1109412:AWC36_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HemG family.|||Belongs to the flavodoxin family.|||Binds 1 FMN non-covalently per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPQ6 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1109412:AWC36_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1L0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS21205 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV89 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1109412:AWC36_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP55 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1109412:AWC36_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0J1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1109412:AWC36_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BtuF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.|||Periplasm|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/1109412:AWC36_RS11960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP17 ^@ Function|||Similarity ^@ Belongs to the cycloisomerase 2 family.|||Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1109412:AWC36_RS22960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1109412:AWC36_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZB7 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1109412:AWC36_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ84 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS23255 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWY1 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/1109412:AWC36_RS22510 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Cell membrane|||Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A250BFD3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A250BCQ3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1109412:AWC36_RS15650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1109412:AWC36_RS20410 ^@ http://purl.uniprot.org/uniprot/A0A250BJF8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZD1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS14975 ^@ http://purl.uniprot.org/uniprot/A0A250BG79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Cell inner membrane|||Membrane|||Transports acetate. http://togogenome.org/gene/1109412:AWC36_RS14660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQP0 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1109412:AWC36_RS13740 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS12730 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ20 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1109412:AWC36_RS21405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUR5 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1109412:AWC36_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRC4 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21315 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUL0 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/1109412:AWC36_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A250BLX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS14300 ^@ http://purl.uniprot.org/uniprot/A0A250BFX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09580 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS19325 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/1109412:AWC36_RS18425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/1109412:AWC36_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A250BKV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0312 family. Type 1 subfamily.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A250BA45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11975 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1109412:AWC36_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPG2 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1109412:AWC36_RS18025 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1109412:AWC36_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0G4K088 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/1109412:AWC36_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A250BL38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/1109412:AWC36_RS14330 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQI0 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSJ4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/1109412:AWC36_RS11100 ^@ http://purl.uniprot.org/uniprot/A0A250BEQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.|||Cell membrane|||Efflux system for nickel and cobalt.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0G6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1109412:AWC36_RS22865 ^@ http://purl.uniprot.org/uniprot/A0A250BK56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A0G4K297 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS18590 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1109412:AWC36_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0T2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/1109412:AWC36_RS21650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUU5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1109412:AWC36_RS23285 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/1109412:AWC36_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0R5 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/1109412:AWC36_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYY4 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1109412:AWC36_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS22420 ^@ http://purl.uniprot.org/uniprot/A0A250BKZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1109412:AWC36_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0N8 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1109412:AWC36_RS16185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRL8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS06855 ^@ http://purl.uniprot.org/uniprot/A0A0G4K012 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZN7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1109412:AWC36_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1109412:AWC36_RS23185 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1109412:AWC36_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/1109412:AWC36_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVW5 ^@ Function|||Similarity ^@ Belongs to the ETF-QO/FixC family.|||Part of an electron transfer system. http://togogenome.org/gene/1109412:AWC36_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWT4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/1109412:AWC36_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A250BCT2 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/1109412:AWC36_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1W5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/1109412:AWC36_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1G6 ^@ Similarity ^@ Belongs to the UPF0181 family. http://togogenome.org/gene/1109412:AWC36_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0X8 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/1109412:AWC36_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZR8 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/1109412:AWC36_RS15265 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. http://togogenome.org/gene/1109412:AWC36_RS17250 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1109412:AWC36_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A0G4K278 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A0G4K128 ^@ Function|||Subunit ^@ Interacts with sigma-54.|||Required for activation of most nif operons, which are directly involved in nitrogen fixation. http://togogenome.org/gene/1109412:AWC36_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXC7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1109412:AWC36_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13355 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPT1 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/1109412:AWC36_RS20315 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU08 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1109412:AWC36_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0R9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPF6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/1109412:AWC36_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZC4 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/1109412:AWC36_RS14495 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQP5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS20230 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTX7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/1109412:AWC36_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A250BL16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPL4 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/1109412:AWC36_RS19335 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1K8 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS09765 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2H2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS19225 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXW3 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1109412:AWC36_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1P4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).|||Membrane http://togogenome.org/gene/1109412:AWC36_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/1109412:AWC36_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP83 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1109412:AWC36_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TatA/E family. TatE subfamily.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA. http://togogenome.org/gene/1109412:AWC36_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS11915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS21395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS23210 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1109412:AWC36_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2P9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/1109412:AWC36_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT69 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS11675 ^@ http://purl.uniprot.org/uniprot/A0A0G4K3P4 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1109412:AWC36_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22430 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVD8 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1109412:AWC36_RS19375 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21505 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUT0 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A0G4K205 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/1109412:AWC36_RS13055 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ45 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1109412:AWC36_RS18775 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1109412:AWC36_RS15260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS22920 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVB6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1109412:AWC36_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZS5 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/1109412:AWC36_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXT3 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1109412:AWC36_RS19395 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTH6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1109412:AWC36_RS22760 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS19950 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1109412:AWC36_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0G1 ^@ Similarity ^@ Belongs to the UPF0482 family. http://togogenome.org/gene/1109412:AWC36_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A0G4K261 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1109412:AWC36_RS13595 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPY6 ^@ Similarity ^@ Belongs to the UPF0253 family. http://togogenome.org/gene/1109412:AWC36_RS22340 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1109412:AWC36_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWS1 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1109412:AWC36_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS14700 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQP6 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1109412:AWC36_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZT1 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1109412:AWC36_RS17005 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1109412:AWC36_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0T7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1109412:AWC36_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP56 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1109412:AWC36_RS22450 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVT8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1109412:AWC36_RS19715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTS0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A0G4K218 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWX6 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1109412:AWC36_RS04425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYN7 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/1109412:AWC36_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRB1 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1109412:AWC36_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ10 ^@ Activity Regulation|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1109412:AWC36_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS18785 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1109412:AWC36_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A0G4JY44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A250BKX3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1109412:AWC36_RS18515 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSV8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07010 ^@ http://purl.uniprot.org/uniprot/A0A0G4K038 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1109412:AWC36_RS09860 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS18800 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT66 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/1109412:AWC36_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0266 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A0G4K177 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1109412:AWC36_RS21465 ^@ http://purl.uniprot.org/uniprot/A0A250BJL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1109412:AWC36_RS13660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1109412:AWC36_RS23615 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVT9 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1109412:AWC36_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS22125 ^@ http://purl.uniprot.org/uniprot/A0A250BM13 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1109412:AWC36_RS13885 ^@ http://purl.uniprot.org/uniprot/A0A250BFP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MutH family.|||Cytoplasm|||Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. http://togogenome.org/gene/1109412:AWC36_RS13000 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A0G4K274 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23315 ^@ http://purl.uniprot.org/uniprot/A0A250BM30 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1109412:AWC36_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A250BBI0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1109412:AWC36_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A250BEL9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1109412:AWC36_RS17740 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS18050 ^@ http://purl.uniprot.org/uniprot/A0A250BI84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A250BCY6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1109412:AWC36_RS15430 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRN9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS23575 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVS8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1109412:AWC36_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A0G4JR93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1109412:AWC36_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS21350 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUM0 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/1109412:AWC36_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWK9 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/1109412:AWC36_RS14425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/1109412:AWC36_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYR0 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/1109412:AWC36_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1W3 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1109412:AWC36_RS21485 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1109412:AWC36_RS21470 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS21300 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVB0 ^@ Similarity ^@ Belongs to the acetyltransferase YopJ family. http://togogenome.org/gene/1109412:AWC36_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaA family. HdA subfamily.|||Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.|||The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN). http://togogenome.org/gene/1109412:AWC36_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2V3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYD5 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/1109412:AWC36_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1109412:AWC36_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A0G4K022 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/1109412:AWC36_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPN6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1109412:AWC36_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0R8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/1109412:AWC36_RS18180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS21330 ^@ http://purl.uniprot.org/uniprot/A0A250BJV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.|||Cell inner membrane|||Interacts with KefB.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. http://togogenome.org/gene/1109412:AWC36_RS12110 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1109412:AWC36_RS22465 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV81 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1109412:AWC36_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A0G4K091 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/1109412:AWC36_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20180 ^@ http://purl.uniprot.org/uniprot/A0A0G4JTW6 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1109412:AWC36_RS13940 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW27 ^@ Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Hexamer of two alpha, two beta, and two delta chains. http://togogenome.org/gene/1109412:AWC36_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXD9 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1109412:AWC36_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23205 ^@ http://purl.uniprot.org/uniprot/A0A250BKB9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1109412:AWC36_RS21685 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUV7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aldolase class II family. RhaD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1109412:AWC36_RS18295 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16160 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A0G4K122 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1109412:AWC36_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A250BF98 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS15505 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRA2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1109412:AWC36_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ37 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1109412:AWC36_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSF5 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1109412:AWC36_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS16620 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSK4 ^@ Similarity ^@ Belongs to the UPF0306 family. http://togogenome.org/gene/1109412:AWC36_RS21540 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVF4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1109412:AWC36_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Syd family.|||Cell inner membrane|||Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. http://togogenome.org/gene/1109412:AWC36_RS17055 ^@ http://purl.uniprot.org/uniprot/A0A250BHF3 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/1109412:AWC36_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1109412:AWC36_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17400 ^@ http://purl.uniprot.org/uniprot/A0A250BHX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0E7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1109412:AWC36_RS11655 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2Y7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1109412:AWC36_RS22425 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVT6 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1109412:AWC36_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS43 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1109412:AWC36_RS12025 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP33 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1109412:AWC36_RS14950 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A250BLU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS17900 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1109412:AWC36_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX70 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1109412:AWC36_RS10790 ^@ http://purl.uniprot.org/uniprot/A0A0G4K2B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1G4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1109412:AWC36_RS16900 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS07 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1109412:AWC36_RS21365 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrE/TusD family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. http://togogenome.org/gene/1109412:AWC36_RS13910 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ69 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1109412:AWC36_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS15740 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRV9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1109412:AWC36_RS10785 ^@ http://purl.uniprot.org/uniprot/A0A0G4K304 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1109412:AWC36_RS23260 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW79 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWA9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1109412:AWC36_RS20875 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUF4 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1109412:AWC36_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZG1 ^@ Function|||Similarity ^@ Belongs to the glutathione peroxidase family. BtuE subfamily.|||Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. http://togogenome.org/gene/1109412:AWC36_RS21385 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVC7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1109412:AWC36_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ59 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1109412:AWC36_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP58 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1109412:AWC36_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS13195 ^@ http://purl.uniprot.org/uniprot/A0A250BFQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A250BDW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1109412:AWC36_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A0G4JW61 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS23645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWI1 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1109412:AWC36_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JSM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PanZ/PanM family.|||Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.|||Interacts with PanD in the presence of CoA. http://togogenome.org/gene/1109412:AWC36_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0U4 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1109412:AWC36_RS16465 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS20845 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUC7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1109412:AWC36_RS22835 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVC0 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1109412:AWC36_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1109412:AWC36_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A250BBU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/1109412:AWC36_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWK8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1109412:AWC36_RS22165 ^@ http://purl.uniprot.org/uniprot/A0A0G4JV35 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1109412:AWC36_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A0G4K071 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1109412:AWC36_RS15715 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRV2 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1109412:AWC36_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1109412:AWC36_RS21310 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUP2 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/1109412:AWC36_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1K0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A250BBS1 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1109412:AWC36_RS21285 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUN7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1109412:AWC36_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A250BKS3 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/1109412:AWC36_RS12495 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/1109412:AWC36_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1N9 ^@ Similarity|||Subunit ^@ Belongs to the glutaredoxin family.|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1U2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS21515 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1109412:AWC36_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1109412:AWC36_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/1109412:AWC36_RS23650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVX7 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1109412:AWC36_RS20305 ^@ http://purl.uniprot.org/uniprot/A0A250BJD0 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1109412:AWC36_RS20660 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A0G4K144 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1109412:AWC36_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A0G4JXU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1109412:AWC36_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A0G4K187 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1109412:AWC36_RS23245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JVJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1109412:AWC36_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1109412:AWC36_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1109412:AWC36_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS58 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1109412:AWC36_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZ46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LpoB family.|||Cell outer membrane|||Interacts with PBP1b.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). http://togogenome.org/gene/1109412:AWC36_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0T9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RssB family.|||Binds to RpoS.|||Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.|||Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. http://togogenome.org/gene/1109412:AWC36_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPL3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1109412:AWC36_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A0G4JYH1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Cell membrane|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1109412:AWC36_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A250BH12 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1109412:AWC36_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0P2 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/1109412:AWC36_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0G4K1X1 ^@ Similarity ^@ Belongs to the DsrB family. http://togogenome.org/gene/1109412:AWC36_RS17065 ^@ http://purl.uniprot.org/uniprot/A0A250BHA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1109412:AWC36_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A0G4K0D8 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1109412:AWC36_RS21190 ^@ http://purl.uniprot.org/uniprot/A0A250BJG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1109412:AWC36_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A0G4JWZ3 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1109412:AWC36_RS21210 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUM1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1109412:AWC36_RS15405 ^@ http://purl.uniprot.org/uniprot/A0A0G4JRN4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1109412:AWC36_RS21245 ^@ http://purl.uniprot.org/uniprot/A0A0G4JUJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1109412:AWC36_RS19130 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU03 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1109412:AWC36_RS12915 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ38 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1109412:AWC36_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A250BFW4 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1109412:AWC36_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A0G4K196 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1109412:AWC36_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A0G4JS32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbD subfamily.|||Cell inner membrane|||Membrane|||Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. http://togogenome.org/gene/1109412:AWC36_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0G4JX77 ^@ Function|||Subunit ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.|||The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau. http://togogenome.org/gene/1109412:AWC36_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A0G4JPI5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1109412:AWC36_RS18745 ^@ http://purl.uniprot.org/uniprot/A0A0G4JT16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1109412:AWC36_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A0G4JQ13 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/1109412:AWC36_RS12035 ^@ http://purl.uniprot.org/uniprot/A0A0G4JP41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/1109412:AWC36_RS20285 ^@ http://purl.uniprot.org/uniprot/A0A0G4JU05 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. http://togogenome.org/gene/1109412:AWC36_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A0G4JZK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the porin LamB (TC 1.B.3) family.|||Membrane http://togogenome.org/gene/1109412:AWC36_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A0G4K006 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily.