http://togogenome.org/gene/1122961:PTO_RS05065 ^@ http://purl.uniprot.org/uniprot/Q6L0F8 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1122961:PTO_RS00265 ^@ http://purl.uniprot.org/uniprot/Q6L313 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/1122961:PTO_RS04580 ^@ http://purl.uniprot.org/uniprot/Q6L0Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/1122961:PTO_RS04760 ^@ http://purl.uniprot.org/uniprot/Q6L0L8 ^@ Similarity|||Subunit ^@ Belongs to the CarB family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1122961:PTO_RS02275 ^@ http://purl.uniprot.org/uniprot/Q6L1Y7 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/1122961:PTO_RS04150 ^@ http://purl.uniprot.org/uniprot/Q6L0Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS07925 ^@ http://purl.uniprot.org/uniprot/Q6KYU4 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/1122961:PTO_RS02725 ^@ http://purl.uniprot.org/uniprot/Q6L1Q0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1122961:PTO_RS00060 ^@ http://purl.uniprot.org/uniprot/Q6L353 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family. http://togogenome.org/gene/1122961:PTO_RS06025 ^@ http://purl.uniprot.org/uniprot/Q6KZW9 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1122961:PTO_RS02875 ^@ http://purl.uniprot.org/uniprot/Q6L1M1 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/1122961:PTO_RS01170 ^@ http://purl.uniprot.org/uniprot/Q6L2J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS07845 ^@ http://purl.uniprot.org/uniprot/Q6KYW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS04450 ^@ http://purl.uniprot.org/uniprot/Q6L0S6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1122961:PTO_RS07495 ^@ http://purl.uniprot.org/uniprot/Q6KZ30 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS07985 ^@ http://purl.uniprot.org/uniprot/Q6KYT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03450 ^@ http://purl.uniprot.org/uniprot/Q6L1B6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS03820 ^@ http://purl.uniprot.org/uniprot/Q6L144 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSL4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. http://togogenome.org/gene/1122961:PTO_RS06750 ^@ http://purl.uniprot.org/uniprot/Q6KZH9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1122961:PTO_RS03045 ^@ http://purl.uniprot.org/uniprot/Q6L1I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS02150 ^@ http://purl.uniprot.org/uniprot/Q6L212 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/1122961:PTO_RS04325 ^@ http://purl.uniprot.org/uniprot/Q6L0V1 ^@ Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/1122961:PTO_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX35|||http://purl.uniprot.org/uniprot/Q6KZI7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A8G2L722|||http://purl.uniprot.org/uniprot/Q6L1H6 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04610 ^@ http://purl.uniprot.org/uniprot/Q6L0P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcL subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/1122961:PTO_RS02895 ^@ http://purl.uniprot.org/uniprot/Q6L1L7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS03105 ^@ http://purl.uniprot.org/uniprot/Q6L1H9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1122961:PTO_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVY1|||http://purl.uniprot.org/uniprot/Q6L1B1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1122961:PTO_RS07295 ^@ http://purl.uniprot.org/uniprot/Q6KZ70 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.|||Belongs to the asparaginase 1 family. GatD subfamily.|||Heterodimer of GatD and GatE. http://togogenome.org/gene/1122961:PTO_RS00540 ^@ http://purl.uniprot.org/uniprot/Q6L2W1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS02610 ^@ http://purl.uniprot.org/uniprot/Q6L1S2 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/1122961:PTO_RS00450 ^@ http://purl.uniprot.org/uniprot/Q6L2X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS00800 ^@ http://purl.uniprot.org/uniprot/Q6L2R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1122961:PTO_RS06510 ^@ http://purl.uniprot.org/uniprot/Q6KZM6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1122961:PTO_RS06180 ^@ http://purl.uniprot.org/uniprot/Q6KZU0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS00875 ^@ http://purl.uniprot.org/uniprot/Q6L2P7 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/1122961:PTO_RS02585 ^@ http://purl.uniprot.org/uniprot/Q6L1S7 ^@ Caution|||Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. http://togogenome.org/gene/1122961:PTO_RS02060 ^@ http://purl.uniprot.org/uniprot/Q6L229 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.|||Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure. http://togogenome.org/gene/1122961:PTO_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWH5|||http://purl.uniprot.org/uniprot/Q6L227 ^@ Caution|||Function|||Similarity ^@ Belongs to the pseudouridine synthase Pus10 family.|||Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03990 ^@ http://purl.uniprot.org/uniprot/Q6L110 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS01740 ^@ http://purl.uniprot.org/uniprot/Q6L288 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1122961:PTO_RS04575 ^@ http://purl.uniprot.org/uniprot/Q6L0Q1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.|||Nucleus|||Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure. http://togogenome.org/gene/1122961:PTO_RS06125 ^@ http://purl.uniprot.org/uniprot/Q6KZV1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1122961:PTO_RS02040 ^@ http://purl.uniprot.org/uniprot/Q6L233 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. UPF0219 family. http://togogenome.org/gene/1122961:PTO_RS07200 ^@ http://purl.uniprot.org/uniprot/Q6KZ90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.|||Belongs to the TiaS family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS00070 ^@ http://purl.uniprot.org/uniprot/Q6L351 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1122961:PTO_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY83|||http://purl.uniprot.org/uniprot/Q6L2L3 ^@ Caution|||Similarity ^@ Belongs to the PDCD5 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02500 ^@ http://purl.uniprot.org/uniprot/Q6L1U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07470 ^@ http://purl.uniprot.org/uniprot/Q6KZ35 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1122961:PTO_RS08070 ^@ http://purl.uniprot.org/uniprot/Q6L1P0 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/1122961:PTO_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7L6|||http://purl.uniprot.org/uniprot/Q6L1A7 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Part of the 30S ribosomal subunit. Contacts protein S4.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1122961:PTO_RS05825 ^@ http://purl.uniprot.org/uniprot/Q6L008 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1122961:PTO_RS07030 ^@ http://purl.uniprot.org/uniprot/Q6KZC5 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B). http://togogenome.org/gene/1122961:PTO_RS03050 ^@ http://purl.uniprot.org/uniprot/Q6L1I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS00735 ^@ http://purl.uniprot.org/uniprot/Q6L2S4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1122961:PTO_RS00470 ^@ http://purl.uniprot.org/uniprot/Q6L2X5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1122961:PTO_RS00460 ^@ http://purl.uniprot.org/uniprot/Q6L2X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS03515 ^@ http://purl.uniprot.org/uniprot/Q6L1A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS05640 ^@ http://purl.uniprot.org/uniprot/Q6L046 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS00550 ^@ http://purl.uniprot.org/uniprot/Q6L2V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVY6|||http://purl.uniprot.org/uniprot/Q6L1B2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06115 ^@ http://purl.uniprot.org/uniprot/Q6KZV3 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/1122961:PTO_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX82|||http://purl.uniprot.org/uniprot/Q6L0F2 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Heterooligomer of catalytic and regulatory chains.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07855 ^@ http://purl.uniprot.org/uniprot/Q6KYV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS05485 ^@ http://purl.uniprot.org/uniprot/Q6L077 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1122961:PTO_RS01135 ^@ http://purl.uniprot.org/uniprot/Q6L2J7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. http://togogenome.org/gene/1122961:PTO_RS05645 ^@ http://purl.uniprot.org/uniprot/Q6L045 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01935 ^@ http://purl.uniprot.org/uniprot/Q6L253 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS02620 ^@ http://purl.uniprot.org/uniprot/Q6L1S0 ^@ Similarity ^@ Belongs to the isopentenyl phosphate kinase family. http://togogenome.org/gene/1122961:PTO_RS01490 ^@ http://purl.uniprot.org/uniprot/Q6L2D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWD6|||http://purl.uniprot.org/uniprot/Q6L202 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1122961:PTO_RS04290 ^@ http://purl.uniprot.org/uniprot/Q6L0V6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1122961:PTO_RS07880 ^@ http://purl.uniprot.org/uniprot/Q6KYV3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1122961:PTO_RS03895 ^@ http://purl.uniprot.org/uniprot/Q6L128 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1122961:PTO_RS06480 ^@ http://purl.uniprot.org/uniprot/Q6KZN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.|||Belongs to the peptidase S16 family. Archaeal LonB subfamily.|||Cell membrane|||Homohexamer. Organized in a ring with a central cavity.|||Membrane http://togogenome.org/gene/1122961:PTO_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7D1|||http://purl.uniprot.org/uniprot/Q6KZB3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05130 ^@ http://purl.uniprot.org/uniprot/Q6L0E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/1122961:PTO_RS03155 ^@ http://purl.uniprot.org/uniprot/Q6L1H0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1122961:PTO_RS05010 ^@ http://purl.uniprot.org/uniprot/Q6L0G9 ^@ Similarity ^@ Belongs to the ferrochelatase family. http://togogenome.org/gene/1122961:PTO_RS02935 ^@ http://purl.uniprot.org/uniprot/Q6L1K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal DNA polymerase II family.|||Heterodimer of a large subunit and a small subunit.|||Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). http://togogenome.org/gene/1122961:PTO_RS05320 ^@ http://purl.uniprot.org/uniprot/Q6L0A8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase IV family.|||Binds 1 Fe(2+) ion per subunit.|||Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A8G2L857|||http://purl.uniprot.org/uniprot/Q6KZI5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL24 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02075 ^@ http://purl.uniprot.org/uniprot/Q6L226 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1122961:PTO_RS07175 ^@ http://purl.uniprot.org/uniprot/Q6KZ96 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/1122961:PTO_RS00240 ^@ http://purl.uniprot.org/uniprot/Q6L317 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1122961:PTO_RS05660 ^@ http://purl.uniprot.org/uniprot/Q6L042 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1122961:PTO_RS02395 ^@ http://purl.uniprot.org/uniprot/Q6L1W3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeosine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. http://togogenome.org/gene/1122961:PTO_RS06660 ^@ http://purl.uniprot.org/uniprot/Q6KZJ7 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/1122961:PTO_RS05405 ^@ http://purl.uniprot.org/uniprot/Q6L092 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS03225 ^@ http://purl.uniprot.org/uniprot/Q6L1F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY42|||http://purl.uniprot.org/uniprot/Q6L2L2 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02090 ^@ http://purl.uniprot.org/uniprot/Q6L223 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp41 subfamily.|||Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS00945 ^@ http://purl.uniprot.org/uniprot/Q6L2N4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GGGP/HepGP synthase family. Group II subfamily.|||Cytoplasm|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/1122961:PTO_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWS7|||http://purl.uniprot.org/uniprot/Q6KZ24 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW74 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00075 ^@ http://purl.uniprot.org/uniprot/Q6L350 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1122961:PTO_RS00010 ^@ http://purl.uniprot.org/uniprot/Q6L363 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1122961:PTO_RS05460 ^@ http://purl.uniprot.org/uniprot/Q6L082 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS04700 ^@ http://purl.uniprot.org/uniprot/Q6L0M8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1122961:PTO_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6Y1|||http://purl.uniprot.org/uniprot/Q6L1C0 ^@ Caution|||Similarity ^@ Belongs to the universal ribosomal protein uL29 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWC2|||http://purl.uniprot.org/uniprot/Q6L1Y0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03875 ^@ http://purl.uniprot.org/uniprot/Q6L132 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1122961:PTO_RS02605 ^@ http://purl.uniprot.org/uniprot/Q6L1S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS00775 ^@ http://purl.uniprot.org/uniprot/Q6L2R7 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1122961:PTO_RS06360 ^@ http://purl.uniprot.org/uniprot/Q6KZQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. Fibrillarin family.|||Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.|||Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. http://togogenome.org/gene/1122961:PTO_RS05895 ^@ http://purl.uniprot.org/uniprot/Q6KZZ4 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1122961:PTO_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWJ7|||http://purl.uniprot.org/uniprot/Q6L270 ^@ Caution|||Similarity ^@ Belongs to the UPF0145 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW11|||http://purl.uniprot.org/uniprot/Q6L1F6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03390 ^@ http://purl.uniprot.org/uniprot/Q6L1C7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/1122961:PTO_RS06045 ^@ http://purl.uniprot.org/uniprot/Q6KZW6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7G5 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL40 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06665 ^@ http://purl.uniprot.org/uniprot/Q6KZJ6 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1122961:PTO_RS01430 ^@ http://purl.uniprot.org/uniprot/Q6L2E5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1122961:PTO_RS06435 ^@ http://purl.uniprot.org/uniprot/Q6KZP1 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1122961:PTO_RS06925 ^@ http://purl.uniprot.org/uniprot/Q6KZE5 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1122961:PTO_RS01555 ^@ http://purl.uniprot.org/uniprot/Q6L2C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS05000 ^@ http://purl.uniprot.org/uniprot/Q6L0H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS02750 ^@ http://purl.uniprot.org/uniprot/Q6L1P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS07560 ^@ http://purl.uniprot.org/uniprot/Q6KZ18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS06655 ^@ http://purl.uniprot.org/uniprot/Q6KZJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01240 ^@ http://purl.uniprot.org/uniprot/Q6L2H7 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MRE11/RAD32 family.|||Binds 2 manganese ions per subunit.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Nuclease activity is regulated by Rad50.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. http://togogenome.org/gene/1122961:PTO_RS01095 ^@ http://purl.uniprot.org/uniprot/Q6L2K5 ^@ Similarity ^@ Belongs to the UPF0284 family. http://togogenome.org/gene/1122961:PTO_RS03860 ^@ http://purl.uniprot.org/uniprot/Q6L135 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/1122961:PTO_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6V7|||http://purl.uniprot.org/uniprot/Q6L1B9 ^@ Caution|||Similarity ^@ Belongs to the SUI1 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6Y7|||http://purl.uniprot.org/uniprot/Q6L174 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05160 ^@ http://purl.uniprot.org/uniprot/Q6L0E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVF9|||http://purl.uniprot.org/uniprot/Q6L0P2 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02780 ^@ http://purl.uniprot.org/uniprot/Q6L1N9 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 zinc ion.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1122961:PTO_RS02660 ^@ http://purl.uniprot.org/uniprot/Q6L1R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1122961:PTO_RS05220 ^@ http://purl.uniprot.org/uniprot/Q6L0C8 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/1122961:PTO_RS05780 ^@ http://purl.uniprot.org/uniprot/Q6L017 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1122961:PTO_RS00455 ^@ http://purl.uniprot.org/uniprot/Q6L2X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS01280 ^@ http://purl.uniprot.org/uniprot/Q6L2H0 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1122961:PTO_RS07530 ^@ http://purl.uniprot.org/uniprot/Q6KZ23 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/1122961:PTO_RS06030 ^@ http://purl.uniprot.org/uniprot/Q6KZW8 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1122961:PTO_RS06525 ^@ http://purl.uniprot.org/uniprot/Q6KZM3 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1122961:PTO_RS02465 ^@ http://purl.uniprot.org/uniprot/Q6L1V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS07475 ^@ http://purl.uniprot.org/uniprot/Q6KZ34 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1122961:PTO_RS07635 ^@ http://purl.uniprot.org/uniprot/Q6KZ04 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1122961:PTO_RS03125 ^@ http://purl.uniprot.org/uniprot/Q6L1H5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. http://togogenome.org/gene/1122961:PTO_RS06675 ^@ http://purl.uniprot.org/uniprot/Q6KZJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1122961:PTO_RS03040 ^@ http://purl.uniprot.org/uniprot/Q6L1I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWU4|||http://purl.uniprot.org/uniprot/Q6KZ89 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02525 ^@ http://purl.uniprot.org/uniprot/Q6L1T9 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the mevalonate 3,5-bisphosphate decarboxylase family.|||Catalyzes the ATP-independent decarboxylation of (R)-mevalonate 3,5-bisphosphate to isopentenyl phosphate. Functions in an alternative mevalonate pathway, only present in extreme acidophiles of the Thermoplasmatales order, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate. Shows no detectable decarboxylase activity on mevalonate, mevalonate 3-phosphate, mevalonate 5-phosphate or mevalonate 5-pyrophosphate.|||Homodimer.|||It is proposed that Thermoplasmatales adapted the classical archaeal mevalonate pathway by replacing mevalonate 5-phosphate decarboxylase (MMD) with two specialized enzymes (mevalonate-3-phosphate 5-kinase and mevalonate 3,5-bisphosphate decarboxylase) in order to produce isoprenoids in extremely acidic environments. It was found that at low pH, the dual function enzyme MMD is unable to carry out the first phosphorylation step, yet retains its ability to perform decarboxylation. http://togogenome.org/gene/1122961:PTO_RS05765 ^@ http://purl.uniprot.org/uniprot/Q6L020 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03530 ^@ http://purl.uniprot.org/uniprot/Q6L1A0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1122961:PTO_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A8G2L870|||http://purl.uniprot.org/uniprot/Q6KZP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the RNA polymerase complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01075 ^@ http://purl.uniprot.org/uniprot/Q6L2K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXR7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A8G2L808 ^@ Caution|||Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVV3|||http://purl.uniprot.org/uniprot/Q6L1B0 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06080 ^@ http://purl.uniprot.org/uniprot/Q6KZW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXA4|||http://purl.uniprot.org/uniprot/Q6KZP8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06320 ^@ http://purl.uniprot.org/uniprot/Q6KZR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1122961:PTO_RS07275 ^@ http://purl.uniprot.org/uniprot/Q6KZ74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS04530 ^@ http://purl.uniprot.org/uniprot/Q6L0R1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1122961:PTO_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVW1|||http://purl.uniprot.org/uniprot/Q6L1B3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03385 ^@ http://purl.uniprot.org/uniprot/Q6L1C8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.|||Binds 2 Zn(2+) ions per subunit. One of the zinc atoms is essential for catalytic activity while the other has a structural function.|||Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. http://togogenome.org/gene/1122961:PTO_RS01050 ^@ http://purl.uniprot.org/uniprot/Q6L2L4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS02235 ^@ http://purl.uniprot.org/uniprot/Q6L1Z5 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1122961:PTO_RS05665 ^@ http://purl.uniprot.org/uniprot/Q6L041 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1122961:PTO_RS03690 ^@ http://purl.uniprot.org/uniprot/Q6L170 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.|||Homodimer.|||Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. http://togogenome.org/gene/1122961:PTO_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVT4|||http://purl.uniprot.org/uniprot/Q6L181 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01990 ^@ http://purl.uniprot.org/uniprot/Q6L243 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Fe(2+) ion per subunit.|||Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.|||Cytoplasm|||In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.|||In the N-terminal section; belongs to the KAE1 / TsaD family.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. http://togogenome.org/gene/1122961:PTO_RS02240 ^@ http://purl.uniprot.org/uniprot/Q6L1Z4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS05735 ^@ http://purl.uniprot.org/uniprot/Q6L026 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/1122961:PTO_RS04135 ^@ http://purl.uniprot.org/uniprot/Q6L0Y5 ^@ Similarity ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily. http://togogenome.org/gene/1122961:PTO_RS06715 ^@ http://purl.uniprot.org/uniprot/A0A8G2L855|||http://purl.uniprot.org/uniprot/Q6KZI6 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00910 ^@ http://purl.uniprot.org/uniprot/Q6L2P2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS01310 ^@ http://purl.uniprot.org/uniprot/Q6L2G5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1122961:PTO_RS03925 ^@ http://purl.uniprot.org/uniprot/Q6L122 ^@ Similarity ^@ Belongs to the PurH family. http://togogenome.org/gene/1122961:PTO_RS07020 ^@ http://purl.uniprot.org/uniprot/Q6KZC7 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1122961:PTO_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW60|||http://purl.uniprot.org/uniprot/Q6L1N3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAC-alpha family.|||Contacts the emerging nascent chain on the ribosome.|||Homodimer. Interacts with the ribosome. Binds ribosomal RNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A8G2L738|||http://purl.uniprot.org/uniprot/Q6L1V2 ^@ Caution|||Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03415 ^@ http://purl.uniprot.org/uniprot/Q6L1C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1122961:PTO_RS00495 ^@ http://purl.uniprot.org/uniprot/Q6L2X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03395 ^@ http://purl.uniprot.org/uniprot/Q6L1C6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS03400 ^@ http://purl.uniprot.org/uniprot/Q6L1C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/1122961:PTO_RS02790 ^@ http://purl.uniprot.org/uniprot/Q6L1N7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1122961:PTO_RS07375 ^@ http://purl.uniprot.org/uniprot/Q6KZ54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS05480 ^@ http://purl.uniprot.org/uniprot/Q6L078 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1122961:PTO_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7K0|||http://purl.uniprot.org/uniprot/Q6L150 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04265 ^@ http://purl.uniprot.org/uniprot/Q6L0W0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/1122961:PTO_RS07500 ^@ http://purl.uniprot.org/uniprot/Q6KZ29 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS01820 ^@ http://purl.uniprot.org/uniprot/Q6L272 ^@ Function ^@ The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1122961:PTO_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVX5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00975 ^@ http://purl.uniprot.org/uniprot/Q6L2M8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.|||Monomer.|||The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity. http://togogenome.org/gene/1122961:PTO_RS04035 ^@ http://purl.uniprot.org/uniprot/Q6L101 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS05455 ^@ http://purl.uniprot.org/uniprot/Q6L083 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS03685 ^@ http://purl.uniprot.org/uniprot/Q6L171 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aTrm56 family.|||Cytoplasm|||Homodimer.|||Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. http://togogenome.org/gene/1122961:PTO_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX87|||http://purl.uniprot.org/uniprot/Q6KZQ3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07820 ^@ http://purl.uniprot.org/uniprot/Q6KYW5 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1122961:PTO_RS01705 ^@ http://purl.uniprot.org/uniprot/Q6L294 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1122961:PTO_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWD4|||http://purl.uniprot.org/uniprot/Q6L201 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00565 ^@ http://purl.uniprot.org/uniprot/Q3V8B2 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1122961:PTO_RS06515 ^@ http://purl.uniprot.org/uniprot/Q6KZM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the formiminotransferase family.|||Catalyzes the transfer of the formyl group from N-formylglutamate to tetrahydrofolate (THF) to yield 5-formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH=CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrofolate (5,10-CH=THF).|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS02160 ^@ http://purl.uniprot.org/uniprot/Q6L210 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS07690 ^@ http://purl.uniprot.org/uniprot/Q6KYZ2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS03490 ^@ http://purl.uniprot.org/uniprot/Q6L1A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1122961:PTO_RS05860 ^@ http://purl.uniprot.org/uniprot/Q6L001 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS04495 ^@ http://purl.uniprot.org/uniprot/Q6L0R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 'phage' integrase family. XerA subfamily.|||Cytoplasm|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1122961:PTO_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7P5|||http://purl.uniprot.org/uniprot/Q6L1I0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcS subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07165 ^@ http://purl.uniprot.org/uniprot/Q6KZ98 ^@ Similarity ^@ Belongs to the 4HPPD family. http://togogenome.org/gene/1122961:PTO_RS01215 ^@ http://purl.uniprot.org/uniprot/Q6L2I2 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal PrmC-related family. http://togogenome.org/gene/1122961:PTO_RS06465 ^@ http://purl.uniprot.org/uniprot/Q6KZN5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1122961:PTO_RS02045 ^@ http://purl.uniprot.org/uniprot/Q6L232 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1122961:PTO_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY04|||http://purl.uniprot.org/uniprot/Q6L2I0 ^@ Caution|||Similarity ^@ Belongs to the acylphosphatase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05565 ^@ http://purl.uniprot.org/uniprot/Q6L061 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/1122961:PTO_RS02855 ^@ http://purl.uniprot.org/uniprot/Q6L1M5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1122961:PTO_RS01185 ^@ http://purl.uniprot.org/uniprot/Q6L2I8 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family. RadB subfamily.|||Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. http://togogenome.org/gene/1122961:PTO_RS07380 ^@ http://purl.uniprot.org/uniprot/Q6KZ53 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/1122961:PTO_RS01265 ^@ http://purl.uniprot.org/uniprot/Q6L2H3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6T9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07585 ^@ http://purl.uniprot.org/uniprot/Q6KZ13 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/1122961:PTO_RS01460 ^@ http://purl.uniprot.org/uniprot/Q6L2D9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS02305 ^@ http://purl.uniprot.org/uniprot/Q6L1Y1 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/1122961:PTO_RS01815 ^@ http://purl.uniprot.org/uniprot/Q6L273 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS01480 ^@ http://purl.uniprot.org/uniprot/Q6L2D5 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1122961:PTO_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW50|||http://purl.uniprot.org/uniprot/Q6L1Q1 ^@ Caution|||Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02800 ^@ http://purl.uniprot.org/uniprot/Q6L1N5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1122961:PTO_RS01785 ^@ http://purl.uniprot.org/uniprot/Q6L279 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07775 ^@ http://purl.uniprot.org/uniprot/Q6KYX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVT6|||http://purl.uniprot.org/uniprot/Q6L153 ^@ Caution|||Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05340 ^@ http://purl.uniprot.org/uniprot/Q6L0A5 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS04295 ^@ http://purl.uniprot.org/uniprot/Q6L0V5 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1122961:PTO_RS01350 ^@ http://purl.uniprot.org/uniprot/Q6L2F7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1122961:PTO_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A8G2L788|||http://purl.uniprot.org/uniprot/Q6L204 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00655 ^@ http://purl.uniprot.org/uniprot/Q6L2T9 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1122961:PTO_RS07780 ^@ http://purl.uniprot.org/uniprot/Q6KYX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS05995 ^@ http://purl.uniprot.org/uniprot/Q6KZX4 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1122961:PTO_RS00940 ^@ http://purl.uniprot.org/uniprot/Q6L2N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.|||Cell membrane|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/1122961:PTO_RS07215 ^@ http://purl.uniprot.org/uniprot/Q6KZ87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/1122961:PTO_RS01755 ^@ http://purl.uniprot.org/uniprot/Q6L285 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family. Glyceraldehyde dehydrogenase subfamily.|||Homotetramer (By similarity). Dimer of dimers.|||NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.|||Stable for 2 hours at 60 degrees Celsius but activity is decreased to less than 50 percent within 15 minutes at 70 degrees Celsius. http://togogenome.org/gene/1122961:PTO_RS00425 ^@ http://purl.uniprot.org/uniprot/Q6L2Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6M8|||http://purl.uniprot.org/uniprot/Q6L0R4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/1122961:PTO_RS02970 ^@ http://purl.uniprot.org/uniprot/Q6L1K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7K5|||http://purl.uniprot.org/uniprot/Q6L178 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1122961:PTO_RS06460 ^@ http://purl.uniprot.org/uniprot/Q6KZN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXE9|||http://purl.uniprot.org/uniprot/Q6L0C3 ^@ Caution|||Function|||Similarity ^@ Belongs to the LDH/MDH superfamily.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05425 ^@ http://purl.uniprot.org/uniprot/Q6L088 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/1122961:PTO_RS05120 ^@ http://purl.uniprot.org/uniprot/Q6L0E8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeal riboflavin kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). http://togogenome.org/gene/1122961:PTO_RS06375 ^@ http://purl.uniprot.org/uniprot/Q6KZQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07660 ^@ http://purl.uniprot.org/uniprot/Q6KYZ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS04470 ^@ http://purl.uniprot.org/uniprot/Q6L0S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVX7|||http://purl.uniprot.org/uniprot/Q6L1E3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07885 ^@ http://purl.uniprot.org/uniprot/Q6KYV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1122961:PTO_RS05180 ^@ http://purl.uniprot.org/uniprot/Q6L0D6 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1122961:PTO_RS03165 ^@ http://purl.uniprot.org/uniprot/Q6L1G8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS06855 ^@ http://purl.uniprot.org/uniprot/Q6KZF9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1122961:PTO_RS04915 ^@ http://purl.uniprot.org/uniprot/Q6L0I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS06955 ^@ http://purl.uniprot.org/uniprot/Q6KZD9 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1122961:PTO_RS04830 ^@ http://purl.uniprot.org/uniprot/Q6L0K4 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1122961:PTO_RS02080 ^@ http://purl.uniprot.org/uniprot/Q6L225 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS05595 ^@ http://purl.uniprot.org/uniprot/Q6L055 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1122961:PTO_RS00245 ^@ http://purl.uniprot.org/uniprot/Q6L316 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/1122961:PTO_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWE8 ^@ Caution|||Function|||Similarity ^@ Belongs to the NOP10 family.|||Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03315 ^@ http://purl.uniprot.org/uniprot/Q6L1E1 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/1122961:PTO_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A8G2L793 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03175 ^@ http://purl.uniprot.org/uniprot/Q6L1G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS05440 ^@ http://purl.uniprot.org/uniprot/Q6L086 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7G3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00250 ^@ http://purl.uniprot.org/uniprot/Q6L315 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm4 family. http://togogenome.org/gene/1122961:PTO_RS02180 ^@ http://purl.uniprot.org/uniprot/Q6L206 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1122961:PTO_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX12|||http://purl.uniprot.org/uniprot/Q6KZF1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.|||Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS08090 ^@ http://purl.uniprot.org/uniprot/Q6L0J8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family.|||Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1122961:PTO_RS06420 ^@ http://purl.uniprot.org/uniprot/Q6KZP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS07865 ^@ http://purl.uniprot.org/uniprot/Q6KYV6 ^@ Similarity ^@ Belongs to the peptidase S45 family. http://togogenome.org/gene/1122961:PTO_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A8G2L863|||http://purl.uniprot.org/uniprot/Q6KZL5 ^@ Caution|||Function|||Similarity ^@ Belongs to the deoxyhypusine synthase family.|||Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXW9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03280 ^@ http://purl.uniprot.org/uniprot/Q6L1E7 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1122961:PTO_RS04585 ^@ http://purl.uniprot.org/uniprot/Q6L0P9 ^@ Function|||Similarity ^@ Belongs to the GTP-dependent DPCK family.|||Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). http://togogenome.org/gene/1122961:PTO_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVY7|||http://purl.uniprot.org/uniprot/Q6L1B7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01380 ^@ http://purl.uniprot.org/uniprot/Q6L2F3 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/1122961:PTO_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWC5|||http://purl.uniprot.org/uniprot/Q6L1Y6 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVJ8|||http://purl.uniprot.org/uniprot/Q6L0R3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02700 ^@ http://purl.uniprot.org/uniprot/Q6L1Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS02615 ^@ http://purl.uniprot.org/uniprot/Q6L1S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/1122961:PTO_RS00865 ^@ http://purl.uniprot.org/uniprot/Q6L2P9 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1122961:PTO_RS06475 ^@ http://purl.uniprot.org/uniprot/Q6KZN3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1122961:PTO_RS06275 ^@ http://purl.uniprot.org/uniprot/Q6KZS2 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1122961:PTO_RS03520 ^@ http://purl.uniprot.org/uniprot/Q6L1A2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03320 ^@ http://purl.uniprot.org/uniprot/Q6L1E0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1122961:PTO_RS04475 ^@ http://purl.uniprot.org/uniprot/Q6L0S2 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1122961:PTO_RS02050 ^@ http://purl.uniprot.org/uniprot/Q6L231 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS01285 ^@ http://purl.uniprot.org/uniprot/Q6L2G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS07520 ^@ http://purl.uniprot.org/uniprot/Q6KZ25 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the glycerate kinase type-1 family.|||Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also partially utilize GTP, CTP or UTP as phosphate donor.|||Homodimer.|||Magnesium. It could be replaced to some extent by nickel, manganese or cobalt. http://togogenome.org/gene/1122961:PTO_RS01340 ^@ http://purl.uniprot.org/uniprot/Q6L2F9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1122961:PTO_RS06970 ^@ http://purl.uniprot.org/uniprot/Q6KZD6 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1122961:PTO_RS02485 ^@ http://purl.uniprot.org/uniprot/Q6L1U7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1122961:PTO_RS05325 ^@ http://purl.uniprot.org/uniprot/Q6L0A7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal FAD synthase family.|||Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS02595 ^@ http://purl.uniprot.org/uniprot/Q6L1S5 ^@ Function|||Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1122961:PTO_RS04175 ^@ http://purl.uniprot.org/uniprot/Q6L0X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS04105 ^@ http://purl.uniprot.org/uniprot/Q6L0Z1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/1122961:PTO_RS04180 ^@ http://purl.uniprot.org/uniprot/Q6L0X6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1122961:PTO_RS04795 ^@ http://purl.uniprot.org/uniprot/Q6L0L1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/1122961:PTO_RS07905 ^@ http://purl.uniprot.org/uniprot/Q6KYU8 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1122961:PTO_RS07010 ^@ http://purl.uniprot.org/uniprot/Q6KZC9 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1122961:PTO_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXY2|||http://purl.uniprot.org/uniprot/Q6L2T8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00985 ^@ http://purl.uniprot.org/uniprot/Q6L2M6 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS02230 ^@ http://purl.uniprot.org/uniprot/Q6L1Z6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1122961:PTO_RS06535 ^@ http://purl.uniprot.org/uniprot/Q6KZM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS06850 ^@ http://purl.uniprot.org/uniprot/Q6KZG0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/1122961:PTO_RS00335 ^@ http://purl.uniprot.org/uniprot/Q6L2Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/1122961:PTO_RS01120 ^@ http://purl.uniprot.org/uniprot/Q6L2K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS05950 ^@ http://purl.uniprot.org/uniprot/Q6KZY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01335 ^@ http://purl.uniprot.org/uniprot/Q6L2G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1122961:PTO_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7K3|||http://purl.uniprot.org/uniprot/Q6KZL0 ^@ Caution|||Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03185 ^@ http://purl.uniprot.org/uniprot/Q6L1G4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1122961:PTO_RS01825 ^@ http://purl.uniprot.org/uniprot/Q6L271 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1122961:PTO_RS03540 ^@ http://purl.uniprot.org/uniprot/Q6L198 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1122961:PTO_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY63|||http://purl.uniprot.org/uniprot/Q6L2G4 ^@ Caution|||Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02560 ^@ http://purl.uniprot.org/uniprot/Q6L1T2 ^@ Cofactor|||Function|||Induction|||Similarity|||Subunit ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GaD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Constitutively expressed.|||Homooctamer.|||Involved in the degradation of glucose and galactose via the nonphosphorylative variant of Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2-keto-3-deoxygalactonate (KDGal). http://togogenome.org/gene/1122961:PTO_RS02540 ^@ http://purl.uniprot.org/uniprot/Q6L1T6 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/1122961:PTO_RS04755 ^@ http://purl.uniprot.org/uniprot/Q6L0L9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1122961:PTO_RS02550 ^@ http://purl.uniprot.org/uniprot/Q6L1T4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS04990 ^@ http://purl.uniprot.org/uniprot/Q6L0H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1122961:PTO_RS02995 ^@ http://purl.uniprot.org/uniprot/Q6L1J7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1122961:PTO_RS03115 ^@ http://purl.uniprot.org/uniprot/Q6L1H7 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1122961:PTO_RS04735 ^@ http://purl.uniprot.org/uniprot/Q6L0M3 ^@ Similarity ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/1122961:PTO_RS01470 ^@ http://purl.uniprot.org/uniprot/Q6L2D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS02245 ^@ http://purl.uniprot.org/uniprot/Q6L1Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS06795 ^@ http://purl.uniprot.org/uniprot/Q6KZH0 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1122961:PTO_RS07385 ^@ http://purl.uniprot.org/uniprot/Q6KZ52 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/1122961:PTO_RS00430 ^@ http://purl.uniprot.org/uniprot/Q6L2Y2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS07090 ^@ http://purl.uniprot.org/uniprot/Q6KZB4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1122961:PTO_RS02155 ^@ http://purl.uniprot.org/uniprot/Q6L211 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1122961:PTO_RS04445 ^@ http://purl.uniprot.org/uniprot/Q6L0S7 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1122961:PTO_RS07960 ^@ http://purl.uniprot.org/uniprot/Q6KYT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS00235 ^@ http://purl.uniprot.org/uniprot/Q6L318 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1122961:PTO_RS04380 ^@ http://purl.uniprot.org/uniprot/Q6L0T9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01030 ^@ http://purl.uniprot.org/uniprot/Q6L2L8 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/1122961:PTO_RS01775 ^@ http://purl.uniprot.org/uniprot/Q6L281 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1122961:PTO_RS05670 ^@ http://purl.uniprot.org/uniprot/Q6L040 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1122961:PTO_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVH3|||http://purl.uniprot.org/uniprot/Q6L0N2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC61-beta family.|||Cell membrane|||Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.|||Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02345 ^@ http://purl.uniprot.org/uniprot/Q6L1X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SPT5 family.|||Belongs to the archaeal Spt5 family.|||Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).|||Stimulates transcription elongation. http://togogenome.org/gene/1122961:PTO_RS05315 ^@ http://purl.uniprot.org/uniprot/Q6L0A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1122961:PTO_RS01255 ^@ http://purl.uniprot.org/uniprot/Q6L2H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03525 ^@ http://purl.uniprot.org/uniprot/Q6L1A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 2 subfamily.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS06845 ^@ http://purl.uniprot.org/uniprot/Q6KZG1 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/1122961:PTO_RS06290 ^@ http://purl.uniprot.org/uniprot/Q6KZR9 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/1122961:PTO_RS01810 ^@ http://purl.uniprot.org/uniprot/Q6L274 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1122961:PTO_RS05980 ^@ http://purl.uniprot.org/uniprot/Q6KZX7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS01980 ^@ http://purl.uniprot.org/uniprot/Q6L245 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS02535 ^@ http://purl.uniprot.org/uniprot/Q6L1T7 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1122961:PTO_RS04690 ^@ http://purl.uniprot.org/uniprot/Q6L0N0 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/1122961:PTO_RS07455 ^@ http://purl.uniprot.org/uniprot/Q6KZ38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).|||In the C-terminal section; belongs to the endonuclease V family.|||In the N-terminal section; belongs to the MGMT family. http://togogenome.org/gene/1122961:PTO_RS06900 ^@ http://purl.uniprot.org/uniprot/Q6KZF0 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/1122961:PTO_RS05470 ^@ http://purl.uniprot.org/uniprot/Q6L080 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1122961:PTO_RS05615 ^@ http://purl.uniprot.org/uniprot/Q6L051 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/1122961:PTO_RS04980 ^@ http://purl.uniprot.org/uniprot/Q6L0H5 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/1122961:PTO_RS02085 ^@ http://purl.uniprot.org/uniprot/Q6L224 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/1122961:PTO_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWB2|||http://purl.uniprot.org/uniprot/Q6L200 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04500 ^@ http://purl.uniprot.org/uniprot/Q6L0R7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycerol-1-phosphate dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS04740 ^@ http://purl.uniprot.org/uniprot/Q6L0M2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/1122961:PTO_RS00435 ^@ http://purl.uniprot.org/uniprot/Q6L2Y1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1122961:PTO_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVW0|||http://purl.uniprot.org/uniprot/Q6L1C4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05570 ^@ http://purl.uniprot.org/uniprot/Q6L060 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS02580 ^@ http://purl.uniprot.org/uniprot/Q6L1S8 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. http://togogenome.org/gene/1122961:PTO_RS00715 ^@ http://purl.uniprot.org/uniprot/Q6L2S8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX90|||http://purl.uniprot.org/uniprot/Q6L0F1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06885 ^@ http://purl.uniprot.org/uniprot/Q6KZF2 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/1122961:PTO_RS07670 ^@ http://purl.uniprot.org/uniprot/Q6KYZ7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1122961:PTO_RS02880 ^@ http://purl.uniprot.org/uniprot/Q6L1M0 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS02325 ^@ http://purl.uniprot.org/uniprot/Q6L1X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1122961:PTO_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7J3|||http://purl.uniprot.org/uniprot/Q6KZI1 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A8G2FWF7|||http://purl.uniprot.org/uniprot/Q6L228 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03855 ^@ http://purl.uniprot.org/uniprot/Q6L137 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6X5|||http://purl.uniprot.org/uniprot/Q6L1A6 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05205 ^@ http://purl.uniprot.org/uniprot/Q6L0D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX17|||http://purl.uniprot.org/uniprot/Q6KZD1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04955 ^@ http://purl.uniprot.org/uniprot/Q6L0I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07310 ^@ http://purl.uniprot.org/uniprot/Q6KZ67 ^@ Similarity ^@ Belongs to the complex I subunit 3 family. http://togogenome.org/gene/1122961:PTO_RS07350 ^@ http://purl.uniprot.org/uniprot/Q6KZ59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS01640 ^@ http://purl.uniprot.org/uniprot/Q6L2A6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS00555 ^@ http://purl.uniprot.org/uniprot/Q6L2V8 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1122961:PTO_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A8G2L6M3|||http://purl.uniprot.org/uniprot/Q6L0P8 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02515 ^@ http://purl.uniprot.org/uniprot/Q6L1U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS07720 ^@ http://purl.uniprot.org/uniprot/Q6KYY5 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. http://togogenome.org/gene/1122961:PTO_RS07330 ^@ http://purl.uniprot.org/uniprot/Q6KZ63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS03770 ^@ http://purl.uniprot.org/uniprot/Q6L154 ^@ Similarity ^@ Belongs to the DMRL synthase family. http://togogenome.org/gene/1122961:PTO_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVY4|||http://purl.uniprot.org/uniprot/Q6L1E2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03085 ^@ http://purl.uniprot.org/uniprot/Q6L1I2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/1122961:PTO_RS03485 ^@ http://purl.uniprot.org/uniprot/Q6L1A9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS07680 ^@ http://purl.uniprot.org/uniprot/Q6KYZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/1122961:PTO_RS05680 ^@ http://purl.uniprot.org/uniprot/Q6L038 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1122961:PTO_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVM7|||http://purl.uniprot.org/uniprot/Q6L0W3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04505 ^@ http://purl.uniprot.org/uniprot/Q6L0R6 ^@ Similarity ^@ Belongs to the UPF0179 family. http://togogenome.org/gene/1122961:PTO_RS00805 ^@ http://purl.uniprot.org/uniprot/Q6L2R1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1122961:PTO_RS05195 ^@ http://purl.uniprot.org/uniprot/Q6L0D3 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXA0|||http://purl.uniprot.org/uniprot/Q6KZR7 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX24|||http://purl.uniprot.org/uniprot/Q6KZK4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01965 ^@ http://purl.uniprot.org/uniprot/Q6L248 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1122961:PTO_RS07595 ^@ http://purl.uniprot.org/uniprot/Q6KZ11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1122961:PTO_RS00545 ^@ http://purl.uniprot.org/uniprot/Q6L2W0 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1122961:PTO_RS01290 ^@ http://purl.uniprot.org/uniprot/Q6L2G8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1122961:PTO_RS01275 ^@ http://purl.uniprot.org/uniprot/Q6L2H1 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1122961:PTO_RS04640 ^@ http://purl.uniprot.org/uniprot/Q6L0N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS07970 ^@ http://purl.uniprot.org/uniprot/Q6KYT6 ^@ Similarity ^@ Belongs to the sterol desaturase family. http://togogenome.org/gene/1122961:PTO_RS02815 ^@ http://purl.uniprot.org/uniprot/Q6L1N2 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06075 ^@ http://purl.uniprot.org/uniprot/Q6KZW2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. http://togogenome.org/gene/1122961:PTO_RS07430 ^@ http://purl.uniprot.org/uniprot/Q6KZ43 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1122961:PTO_RS07675 ^@ http://purl.uniprot.org/uniprot/Q6KYZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis). http://togogenome.org/gene/1122961:PTO_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXX0|||http://purl.uniprot.org/uniprot/Q6L2J9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the archaeal dihydroneopterin aldolase family.|||Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).|||Homotetramer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW79|||http://purl.uniprot.org/uniprot/Q6L1P9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.|||Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.|||Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).|||Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.|||Homodimer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00725 ^@ http://purl.uniprot.org/uniprot/Q6L2S6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1122961:PTO_RS03005 ^@ http://purl.uniprot.org/uniprot/Q6L1J5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1122961:PTO_RS00475 ^@ http://purl.uniprot.org/uniprot/Q6L2X4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1122961:PTO_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7D4|||http://purl.uniprot.org/uniprot/Q6L0M1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.|||Binds 1 FAD per subunit.|||Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.|||Reduction reaction proceeds via syn addition of hydrogen for double bonds.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03920 ^@ http://purl.uniprot.org/uniprot/Q6L123 ^@ Function|||Similarity ^@ Belongs to the AdoMet synthase 2 family.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/1122961:PTO_RS07270 ^@ http://purl.uniprot.org/uniprot/Q6KZ75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS05400 ^@ http://purl.uniprot.org/uniprot/Q6L093 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS06975 ^@ http://purl.uniprot.org/uniprot/Q6KZD5 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/1122961:PTO_RS03815 ^@ http://purl.uniprot.org/uniprot/Q6L146 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/1122961:PTO_RS01360 ^@ http://purl.uniprot.org/uniprot/Q6L2F6 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1122961:PTO_RS06255 ^@ http://purl.uniprot.org/uniprot/Q6KZS6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1122961:PTO_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX81|||http://purl.uniprot.org/uniprot/Q6KZP6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00870 ^@ http://purl.uniprot.org/uniprot/Q6L2P8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1122961:PTO_RS00700 ^@ http://purl.uniprot.org/uniprot/Q6L2T1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A8G2L783|||http://purl.uniprot.org/uniprot/Q6KYU3 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05935 ^@ http://purl.uniprot.org/uniprot/Q6KZY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/1122961:PTO_RS04240 ^@ http://purl.uniprot.org/uniprot/Q6L0W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase small subunit family.|||Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL). http://togogenome.org/gene/1122961:PTO_RS01345 ^@ http://purl.uniprot.org/uniprot/Q6L2F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta chain family.|||Cytoplasm|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1122961:PTO_RS00850 ^@ http://purl.uniprot.org/uniprot/Q6L2Q2 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1122961:PTO_RS03905 ^@ http://purl.uniprot.org/uniprot/Q6L126 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. http://togogenome.org/gene/1122961:PTO_RS07555 ^@ http://purl.uniprot.org/uniprot/Q6KZ19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY54|||http://purl.uniprot.org/uniprot/Q6L2L0 ^@ Caution|||Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03180 ^@ http://purl.uniprot.org/uniprot/Q6L1G5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1122961:PTO_RS01130 ^@ http://purl.uniprot.org/uniprot/Q6L2J8 ^@ Function|||Similarity ^@ Belongs to the THEP1 NTPase family.|||Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency. http://togogenome.org/gene/1122961:PTO_RS02320 ^@ http://purl.uniprot.org/uniprot/Q6L1X8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1122961:PTO_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7Y1|||http://purl.uniprot.org/uniprot/Q6L293 ^@ Caution|||Similarity ^@ Belongs to the universal ribosomal protein uS9 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03420 ^@ http://purl.uniprot.org/uniprot/Q6L1C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS08105 ^@ http://purl.uniprot.org/uniprot/Q6L0D5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. http://togogenome.org/gene/1122961:PTO_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX40 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06835 ^@ http://purl.uniprot.org/uniprot/Q6KZG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS03610 ^@ http://purl.uniprot.org/uniprot/Q6L186 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS01065 ^@ http://purl.uniprot.org/uniprot/Q6L2L1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/1122961:PTO_RS04390 ^@ http://purl.uniprot.org/uniprot/Q6L0T7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS06950 ^@ http://purl.uniprot.org/uniprot/Q6KZE0 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Potential transporter for phosphate. http://togogenome.org/gene/1122961:PTO_RS01795 ^@ http://purl.uniprot.org/uniprot/Q6L277 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1122961:PTO_RS05600 ^@ http://purl.uniprot.org/uniprot/Q6L054 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS04305 ^@ http://purl.uniprot.org/uniprot/Q6L0V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm|||Degrades oligopeptides. http://togogenome.org/gene/1122961:PTO_RS00860 ^@ http://purl.uniprot.org/uniprot/Q6L2Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS06245 ^@ http://purl.uniprot.org/uniprot/Q6KZS8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS04550 ^@ http://purl.uniprot.org/uniprot/Q6L0Q7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1122961:PTO_RS02680 ^@ http://purl.uniprot.org/uniprot/Q6L1Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic CoaD family.|||Cytoplasm|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1122961:PTO_RS00770 ^@ http://purl.uniprot.org/uniprot/Q6L2R8 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1122961:PTO_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A8G2L704|||http://purl.uniprot.org/uniprot/Q6L1B8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7G1|||http://purl.uniprot.org/uniprot/Q6L0U7 ^@ Caution|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03455 ^@ http://purl.uniprot.org/uniprot/Q6L1B5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/1122961:PTO_RS02705 ^@ http://purl.uniprot.org/uniprot/Q6L1Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS08150 ^@ http://purl.uniprot.org/uniprot/Q6KZ32 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1122961:PTO_RS03765 ^@ http://purl.uniprot.org/uniprot/Q6L155 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06130 ^@ http://purl.uniprot.org/uniprot/Q6KZV0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1122961:PTO_RS07650 ^@ http://purl.uniprot.org/uniprot/Q6KZ01 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. http://togogenome.org/gene/1122961:PTO_RS01235 ^@ http://purl.uniprot.org/uniprot/Q6L2H8 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the SMC family. RAD50 subfamily.|||Binds 1 zinc ion per homodimer.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.|||The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer. http://togogenome.org/gene/1122961:PTO_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A8G2FY26|||http://purl.uniprot.org/uniprot/Q6L2M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07290 ^@ http://purl.uniprot.org/uniprot/Q6KZ71 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS07610 ^@ http://purl.uniprot.org/uniprot/Q6KZ08 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS06865 ^@ http://purl.uniprot.org/uniprot/Q6KZF6 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1122961:PTO_RS03245 ^@ http://purl.uniprot.org/uniprot/Q6L1F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cytoplasm|||Homodimer or homotetramer. http://togogenome.org/gene/1122961:PTO_RS03355 ^@ http://purl.uniprot.org/uniprot/Q6L1D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS02405 ^@ http://purl.uniprot.org/uniprot/Q6L1W1 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1122961:PTO_RS05155 ^@ http://purl.uniprot.org/uniprot/Q6L0E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVE0|||http://purl.uniprot.org/uniprot/Q6L0L2 ^@ Caution|||Similarity ^@ Belongs to the UPF0215 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVB0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00530 ^@ http://purl.uniprot.org/uniprot/Q6L2W3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS06755 ^@ http://purl.uniprot.org/uniprot/Q6KZH8 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1122961:PTO_RS00340 ^@ http://purl.uniprot.org/uniprot/Q6L2Z7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/1122961:PTO_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVY2|||http://purl.uniprot.org/uniprot/Q6L1C3 ^@ Caution|||Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS06980 ^@ http://purl.uniprot.org/uniprot/Q6KZD4 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/1122961:PTO_RS02565 ^@ http://purl.uniprot.org/uniprot/Q6L1T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS07740 ^@ http://purl.uniprot.org/uniprot/Q6KYY1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS05870 ^@ http://purl.uniprot.org/uniprot/Q6KZZ9 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1122961:PTO_RS03910 ^@ http://purl.uniprot.org/uniprot/Q6L125 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1122961:PTO_RS06530 ^@ http://purl.uniprot.org/uniprot/Q6KZM2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1122961:PTO_RS01200 ^@ http://purl.uniprot.org/uniprot/Q6L2I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS05805 ^@ http://purl.uniprot.org/uniprot/Q6L012 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1122961:PTO_RS02590 ^@ http://purl.uniprot.org/uniprot/Q6L1S6 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1122961:PTO_RS07390 ^@ http://purl.uniprot.org/uniprot/Q6KZ51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS07140 ^@ http://purl.uniprot.org/uniprot/Q6KZA3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A8G2FX52|||http://purl.uniprot.org/uniprot/Q6KZP7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1122961:PTO_RS01090 ^@ http://purl.uniprot.org/uniprot/Q6L2K6 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1122961:PTO_RS05060 ^@ http://purl.uniprot.org/uniprot/Q6L0F9 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1122961:PTO_RS05305 ^@ http://purl.uniprot.org/uniprot/Q6L0B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS01715 ^@ http://purl.uniprot.org/uniprot/Q6L292 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1122961:PTO_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7W3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRP4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02670 ^@ http://purl.uniprot.org/uniprot/Q6L1R1 ^@ Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. http://togogenome.org/gene/1122961:PTO_RS04540 ^@ http://purl.uniprot.org/uniprot/Q6L0Q9 ^@ Similarity ^@ Belongs to the SHMT family. http://togogenome.org/gene/1122961:PTO_RS06550 ^@ http://purl.uniprot.org/uniprot/Q6KZL8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVQ7|||http://purl.uniprot.org/uniprot/Q6L140 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1122961:PTO_RS07830 ^@ http://purl.uniprot.org/uniprot/Q6KYW3 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/1122961:PTO_RS01995 ^@ http://purl.uniprot.org/uniprot/Q6L242 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1122961:PTO_RS01330 ^@ http://purl.uniprot.org/uniprot/Q6L2G1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/1122961:PTO_RS01700 ^@ http://purl.uniprot.org/uniprot/Q6L295 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/1122961:PTO_RS03505 ^@ http://purl.uniprot.org/uniprot/Q6L1A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1122961:PTO_RS06250 ^@ http://purl.uniprot.org/uniprot/Q6KZS7 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/1122961:PTO_RS04945 ^@ http://purl.uniprot.org/uniprot/Q6L0I2 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/1122961:PTO_RS05200 ^@ http://purl.uniprot.org/uniprot/Q6L0D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS00080 ^@ http://purl.uniprot.org/uniprot/Q6L349 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1122961:PTO_RS05250 ^@ http://purl.uniprot.org/uniprot/Q6L0C2 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1122961:PTO_RS05190 ^@ http://purl.uniprot.org/uniprot/Q6L0D4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1122961:PTO_RS04490 ^@ http://purl.uniprot.org/uniprot/Q6L0R9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1122961:PTO_RS04935 ^@ http://purl.uniprot.org/uniprot/Q6L0I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS00825 ^@ http://purl.uniprot.org/uniprot/Q6L2Q7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane http://togogenome.org/gene/1122961:PTO_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVA3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01365 ^@ http://purl.uniprot.org/uniprot/Q6L2F5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS07105 ^@ http://purl.uniprot.org/uniprot/Q6KZB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GHMP kinase family.|||Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation.|||Homodimer. http://togogenome.org/gene/1122961:PTO_RS04560 ^@ http://purl.uniprot.org/uniprot/Q6L0Q5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1122961:PTO_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVR7|||http://purl.uniprot.org/uniprot/Q6L152 ^@ Caution|||Similarity ^@ Belongs to the universal ribosomal protein uL16 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS07890 ^@ http://purl.uniprot.org/uniprot/Q6KYV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1122961:PTO_RS02480 ^@ http://purl.uniprot.org/uniprot/Q6L1U8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase delta/II small subunit family.|||Heterodimer of a large subunit and a small subunit.|||Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. http://togogenome.org/gene/1122961:PTO_RS05820 ^@ http://purl.uniprot.org/uniprot/Q6L009 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/1122961:PTO_RS02945 ^@ http://purl.uniprot.org/uniprot/Q6L1K7 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/1122961:PTO_RS07725 ^@ http://purl.uniprot.org/uniprot/Q6KYY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS06260 ^@ http://purl.uniprot.org/uniprot/Q6KZS5 ^@ Cofactor|||Similarity ^@ Belongs to the PdaD family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/1122961:PTO_RS06730 ^@ http://purl.uniprot.org/uniprot/Q6KZI3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. http://togogenome.org/gene/1122961:PTO_RS06785 ^@ http://purl.uniprot.org/uniprot/Q6KZH2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1122961:PTO_RS07315 ^@ http://purl.uniprot.org/uniprot/Q6KZ66 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/1122961:PTO_RS03265 ^@ http://purl.uniprot.org/uniprot/Q6L1F0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the archaeal DnaG primase family.|||Binds two Mg(2+) per subunit.|||Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome. http://togogenome.org/gene/1122961:PTO_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXL9|||http://purl.uniprot.org/uniprot/Q6L013 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-archaeol synthase family.|||Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.|||Cell membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS03550 ^@ http://purl.uniprot.org/uniprot/Q6L197 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/1122961:PTO_RS06295 ^@ http://purl.uniprot.org/uniprot/Q6KZR8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1122961:PTO_RS07625 ^@ http://purl.uniprot.org/uniprot/Q6KZ06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1122961:PTO_RS07300 ^@ http://purl.uniprot.org/uniprot/Q6KZ69 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.|||Belongs to the GatB/GatE family. GatE subfamily.|||Heterodimer of GatD and GatE. http://togogenome.org/gene/1122961:PTO_RS03510 ^@ http://purl.uniprot.org/uniprot/Q6L1A4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1122961:PTO_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A8G2FVW4|||http://purl.uniprot.org/uniprot/Q6L195 ^@ Caution|||Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A8G2L7U9|||http://purl.uniprot.org/uniprot/Q6L1X9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. Probably involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.|||Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05635 ^@ http://purl.uniprot.org/uniprot/Q6L047 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.|||Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Is also significantly active with D-galactose as substrate, but not with D-xylose, L-arabinose, D-ribose, D-mannose, D-allose, D-glucosamine, 2-deoxy-D-glucose, or glucose-6-phosphate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+) (20-fold higher activity). Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.|||Homotetramer.|||Zn(2+) is of critical importance for the stability of the enzyme. http://togogenome.org/gene/1122961:PTO_RS04435 ^@ http://purl.uniprot.org/uniprot/Q6L0S9 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1122961:PTO_RS06325 ^@ http://purl.uniprot.org/uniprot/Q6KZR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1122961:PTO_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A8G2FW05 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A8G2FXV7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS01230 ^@ http://purl.uniprot.org/uniprot/Q6L2H9 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/1122961:PTO_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A8G2L840 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS04910 ^@ http://purl.uniprot.org/uniprot/Q6L0I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1122961:PTO_RS07450 ^@ http://purl.uniprot.org/uniprot/Q6KZ39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1122961:PTO_RS07465 ^@ http://purl.uniprot.org/uniprot/Q6KZ36 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1122961:PTO_RS02460 ^@ http://purl.uniprot.org/uniprot/Q6L1V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1122961:PTO_RS02005 ^@ http://purl.uniprot.org/uniprot/Q6L240 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1122961:PTO_RS06910 ^@ http://purl.uniprot.org/uniprot/Q6KZE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1122961:PTO_RS03205 ^@ http://purl.uniprot.org/uniprot/Q6L1G0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1122961:PTO_RS02655 ^@ http://purl.uniprot.org/uniprot/Q6L1R4 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1122961:PTO_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A8G2L8C5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1122961:PTO_RS05285 ^@ http://purl.uniprot.org/uniprot/Q6L0B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1122961:PTO_RS03935 ^@ http://purl.uniprot.org/uniprot/Q6L120 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1122961:PTO_RS00880 ^@ http://purl.uniprot.org/uniprot/Q6L2P6 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1122961:PTO_RS02805 ^@ http://purl.uniprot.org/uniprot/Q6L1N4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1122961:PTO_RS03460 ^@ http://purl.uniprot.org/uniprot/Q6L1B4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1122961:PTO_RS07835 ^@ http://purl.uniprot.org/uniprot/Q6KYW2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family.