http://togogenome.org/gene/1123384:THY01S_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPP4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ40 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/1123384:THY01S_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ78 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1123384:THY01S_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSY9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1123384:THY01S_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF3 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1123384:THY01S_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS33 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1123384:THY01S_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT92 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1123384:THY01S_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN5 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1123384:THY01S_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1123384:THY01S_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP40 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1123384:THY01S_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPI4 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1123384:THY01S_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS21 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1123384:THY01S_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT27 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1123384:THY01S_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF4 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/1123384:THY01S_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSU3 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1123384:THY01S_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQB2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1123384:THY01S_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQP1 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/1123384:THY01S_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1123384:THY01S_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQA8 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1123384:THY01S_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/1123384:THY01S_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRP1 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1123384:THY01S_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/1123384:THY01S_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ47 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1123384:THY01S_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP94 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1123384:THY01S_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSA8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1123384:THY01S_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ89 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1123384:THY01S_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1123384:THY01S_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNQ0 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1123384:THY01S_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1123384:THY01S_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ52 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1123384:THY01S_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU55 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1123384:THY01S_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPP9 ^@ Similarity|||Subunit ^@ Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1123384:THY01S_RS06980 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Interacts with FtsZ. http://togogenome.org/gene/1123384:THY01S_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQA1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPR2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1123384:THY01S_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1123384:THY01S_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNY2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1123384:THY01S_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1123384:THY01S_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQD9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1123384:THY01S_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT00 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1123384:THY01S_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ30 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1123384:THY01S_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTV6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/1123384:THY01S_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ35 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTB9 ^@ Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. http://togogenome.org/gene/1123384:THY01S_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSG8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1123384:THY01S_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTA0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1123384:THY01S_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPM0 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1123384:THY01S_RS09975 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTE0 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1123384:THY01S_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1123384:THY01S_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1123384:THY01S_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI3 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1123384:THY01S_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1123384:THY01S_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNM0 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/1123384:THY01S_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1123384:THY01S_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRT0 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT72 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1123384:THY01S_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1123384:THY01S_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1123384:THY01S_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1123384:THY01S_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU7 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/1123384:THY01S_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1123384:THY01S_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTJ5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1123384:THY01S_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPK5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1123384:THY01S_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/1123384:THY01S_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPR5 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1123384:THY01S_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1123384:THY01S_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1123384:THY01S_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP60 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/1123384:THY01S_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSB5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1123384:THY01S_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1123384:THY01S_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRX4 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1123384:THY01S_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQQ8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1123384:THY01S_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/1123384:THY01S_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK1 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1123384:THY01S_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ79 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/1123384:THY01S_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB2 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1123384:THY01S_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1123384:THY01S_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPS1 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1123384:THY01S_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS09 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/1123384:THY01S_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQV5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1123384:THY01S_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSM1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1123384:THY01S_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRK0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1123384:THY01S_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSQ7 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1123384:THY01S_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1123384:THY01S_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY5 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/1123384:THY01S_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSA5 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1123384:THY01S_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTW0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1123384:THY01S_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTG4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1123384:THY01S_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQC8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1123384:THY01S_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1123384:THY01S_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSR6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1123384:THY01S_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSR5 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1123384:THY01S_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNY0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1123384:THY01S_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPF6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1123384:THY01S_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1123384:THY01S_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRV0 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1123384:THY01S_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1123384:THY01S_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPW4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS96 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1123384:THY01S_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS64 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1123384:THY01S_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1123384:THY01S_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU76 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1123384:THY01S_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP11 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1123384:THY01S_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1123384:THY01S_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQJ8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1123384:THY01S_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS45 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1123384:THY01S_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1123384:THY01S_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1123384:THY01S_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRF7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1123384:THY01S_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRM2 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1123384:THY01S_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY9 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1123384:THY01S_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQH0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1123384:THY01S_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ7 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/1123384:THY01S_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU2 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1123384:THY01S_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS63 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1123384:THY01S_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTD8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTP0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1123384:THY01S_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1123384:THY01S_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSA9 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1123384:THY01S_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPS8 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1123384:THY01S_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1123384:THY01S_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNM4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1123384:THY01S_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1123384:THY01S_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP91 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTF9 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1123384:THY01S_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ5 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST8 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1123384:THY01S_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU90 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1123384:THY01S_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSJ8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1123384:THY01S_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNV1 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1123384:THY01S_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS40 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS06640 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPH1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1123384:THY01S_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQE0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQV2 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1123384:THY01S_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1123384:THY01S_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQS1 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1123384:THY01S_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQR6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1123384:THY01S_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS09540 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT77 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1123384:THY01S_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ67 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/1123384:THY01S_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSB2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1123384:THY01S_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQE7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1123384:THY01S_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/1123384:THY01S_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUI4 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1123384:THY01S_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRG3 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1123384:THY01S_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRB4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1123384:THY01S_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS91 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1123384:THY01S_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ69 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQH1 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1123384:THY01S_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNU9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1123384:THY01S_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS86 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1123384:THY01S_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQT1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPE9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1123384:THY01S_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1123384:THY01S_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTE4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1123384:THY01S_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPF9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1123384:THY01S_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1123384:THY01S_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSK9 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPA2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1123384:THY01S_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1123384:THY01S_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRY8 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1123384:THY01S_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP79 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1123384:THY01S_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1123384:THY01S_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP04 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/1123384:THY01S_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQZ0 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/1123384:THY01S_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSV2 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/1123384:THY01S_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRL4 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1123384:THY01S_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS3 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1123384:THY01S_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRN8 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/1123384:THY01S_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1123384:THY01S_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1123384:THY01S_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ36 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1123384:THY01S_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS17 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1123384:THY01S_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC1 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/1123384:THY01S_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQI8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1123384:THY01S_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQI7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1123384:THY01S_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR43 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1123384:THY01S_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1123384:THY01S_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1123384:THY01S_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNV9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSQ2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNQ1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1123384:THY01S_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRQ0 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1123384:THY01S_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT84 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRH6 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/1123384:THY01S_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQT4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1123384:THY01S_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTJ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1123384:THY01S_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1123384:THY01S_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRG2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQM0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPE8 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1123384:THY01S_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ6 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1123384:THY01S_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP15 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNY8 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1123384:THY01S_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ73 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1123384:THY01S_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSS9 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/1123384:THY01S_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRQ4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQR0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1123384:THY01S_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS07 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1123384:THY01S_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS42 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1123384:THY01S_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRL6 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1123384:THY01S_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1123384:THY01S_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQC5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1123384:THY01S_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPX2 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1123384:THY01S_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS37 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1123384:THY01S_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPU3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1123384:THY01S_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQS6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1123384:THY01S_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS31 ^@ Function|||Subunit ^@ Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQV7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1123384:THY01S_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1123384:THY01S_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSA3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1123384:THY01S_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF1 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1123384:THY01S_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1123384:THY01S_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTF8 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1123384:THY01S_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1123384:THY01S_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR06 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU86 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1123384:THY01S_RS06635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTS3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSG9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1123384:THY01S_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRW9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1123384:THY01S_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW8 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1123384:THY01S_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1123384:THY01S_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP89 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1123384:THY01S_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1123384:THY01S_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS0 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1123384:THY01S_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSK0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1123384:THY01S_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNP4 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1123384:THY01S_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1123384:THY01S_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNQ7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1123384:THY01S_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSJ0 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/1123384:THY01S_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/1123384:THY01S_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS03 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1123384:THY01S_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT02 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1123384:THY01S_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ2 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1123384:THY01S_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQC4 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1123384:THY01S_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQL1 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPR0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1123384:THY01S_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNQ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1123384:THY01S_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPX0 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQC2 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1123384:THY01S_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPI1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPA8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1123384:THY01S_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQG5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRT3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1123384:THY01S_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRX2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 53 family. http://togogenome.org/gene/1123384:THY01S_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTH3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1123384:THY01S_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNP1 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1123384:THY01S_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQA6 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1123384:THY01S_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS08 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1123384:THY01S_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT05 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ28 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1123384:THY01S_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSA1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1123384:THY01S_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1123384:THY01S_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRT5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1123384:THY01S_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR18 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSC2 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRL8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1123384:THY01S_RS10005 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1123384:THY01S_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ72 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/1123384:THY01S_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPS0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ94 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1123384:THY01S_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1123384:THY01S_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS09235 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQX2 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1123384:THY01S_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP70 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTD5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1123384:THY01S_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPI5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1123384:THY01S_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1123384:THY01S_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNR4 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1123384:THY01S_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR65 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/1123384:THY01S_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1123384:THY01S_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1123384:THY01S_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR49 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1123384:THY01S_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQB8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1123384:THY01S_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP65 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU82 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1123384:THY01S_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP87 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1123384:THY01S_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1123384:THY01S_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB5 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1123384:THY01S_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTA7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1123384:THY01S_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1123384:THY01S_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ20 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1123384:THY01S_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT26 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1123384:THY01S_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI8 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1123384:THY01S_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSB4 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1123384:THY01S_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPH6 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/1123384:THY01S_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT91 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1123384:THY01S_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/1123384:THY01S_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI5 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1123384:THY01S_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI4 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1123384:THY01S_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1123384:THY01S_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1123384:THY01S_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1123384:THY01S_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1123384:THY01S_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1123384:THY01S_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP92 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1123384:THY01S_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1123384:THY01S_RS03595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRZ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1123384:THY01S_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1123384:THY01S_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPP5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/1123384:THY01S_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ33 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRH8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1123384:THY01S_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT67 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1123384:THY01S_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ46 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/1123384:THY01S_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1123384:THY01S_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS02725 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRL5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP88 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1123384:THY01S_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1123384:THY01S_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP77 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1123384:THY01S_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1123384:THY01S_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1123384:THY01S_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRZ1 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1123384:THY01S_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1123384:THY01S_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNR8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1123384:THY01S_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQW3 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/1123384:THY01S_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR94 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1123384:THY01S_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1123384:THY01S_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ70 ^@ Similarity ^@ Belongs to the CTP synthase family. http://togogenome.org/gene/1123384:THY01S_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1123384:THY01S_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1123384:THY01S_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1123384:THY01S_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR09 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS81 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1123384:THY01S_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSN1 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1123384:THY01S_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1123384:THY01S_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR89 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG2 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1123384:THY01S_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPV9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS09460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1123384:THY01S_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQM2 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQT0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/1123384:THY01S_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPM3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNV7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1123384:THY01S_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1123384:THY01S_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQW1 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS09045 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNQ6 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/1123384:THY01S_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT3 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1123384:THY01S_RS09080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNM5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1123384:THY01S_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Cell membrane|||Membrane|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/1123384:THY01S_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTI2 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS87 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1123384:THY01S_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPL0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP28 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1123384:THY01S_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTD0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1123384:THY01S_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1123384:THY01S_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY9 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1123384:THY01S_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ16 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1123384:THY01S_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP56 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/1123384:THY01S_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ82 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRJ4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1123384:THY01S_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ32 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1123384:THY01S_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1123384:THY01S_RS07340 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPF1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRY9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1123384:THY01S_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPH3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1123384:THY01S_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1123384:THY01S_RS00785 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP52 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/1123384:THY01S_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE0 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/1123384:THY01S_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS06855 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1123384:THY01S_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQR7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1123384:THY01S_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQZ8 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1123384:THY01S_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT87 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1123384:THY01S_RS08455 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTG8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1123384:THY01S_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1123384:THY01S_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNU0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1123384:THY01S_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP35 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/1123384:THY01S_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT30 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1123384:THY01S_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP44 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1123384:THY01S_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ98 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/1123384:THY01S_RS10000 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTD6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1123384:THY01S_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1123384:THY01S_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRT6 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1123384:THY01S_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1123384:THY01S_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ18 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/1123384:THY01S_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1123384:THY01S_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPY2 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/1123384:THY01S_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU08 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/1123384:THY01S_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPP1 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1123384:THY01S_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS15 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1123384:THY01S_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRY3 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1123384:THY01S_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSH3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST0 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1123384:THY01S_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQD7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1123384:THY01S_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPC0 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1123384:THY01S_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP76 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1123384:THY01S_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQP4 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1123384:THY01S_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTE3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSN2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1123384:THY01S_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1123384:THY01S_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ24 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1123384:THY01S_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS61 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1123384:THY01S_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRZ8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1123384:THY01S_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY6 ^@ Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. http://togogenome.org/gene/1123384:THY01S_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPU9 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1123384:THY01S_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSZ6 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1123384:THY01S_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPR1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1123384:THY01S_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSI3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS38 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP26 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1123384:THY01S_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE4 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1123384:THY01S_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQT7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY8 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm4 family. http://togogenome.org/gene/1123384:THY01S_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1123384:THY01S_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQB1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1123384:THY01S_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTL9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQL7 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1123384:THY01S_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPN9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1123384:THY01S_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS58 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1123384:THY01S_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD0 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1123384:THY01S_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ86 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1123384:THY01S_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNR9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1123384:THY01S_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1123384:THY01S_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPT0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1123384:THY01S_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUD1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/1123384:THY01S_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1123384:THY01S_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPJ1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1123384:THY01S_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNX3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRM8 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1123384:THY01S_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRU7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1123384:THY01S_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/1123384:THY01S_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1123384:THY01S_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTD9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ44 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1123384:THY01S_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNM8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1123384:THY01S_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSF2 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPH9 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1123384:THY01S_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family. http://togogenome.org/gene/1123384:THY01S_RS06315 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPN3 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRN7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1123384:THY01S_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRS9 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1123384:THY01S_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQD8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1123384:THY01S_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ08 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family. DapH subfamily.|||Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. http://togogenome.org/gene/1123384:THY01S_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPB3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1123384:THY01S_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPX8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1123384:THY01S_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQD1 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1123384:THY01S_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/1123384:THY01S_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRP7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1123384:THY01S_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNK1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPW6 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1123384:THY01S_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR25 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/1123384:THY01S_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTF3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1123384:THY01S_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQW4 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1123384:THY01S_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1123384:THY01S_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPR3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1123384:THY01S_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A0X1KU23 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1123384:THY01S_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1123384:THY01S_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1123384:THY01S_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSL8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1123384:THY01S_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1123384:THY01S_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI2 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1123384:THY01S_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1123384:THY01S_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT07 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/1123384:THY01S_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSU6 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1123384:THY01S_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPJ7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1123384:THY01S_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1123384:THY01S_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1123384:THY01S_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRE8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1123384:THY01S_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPC8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1123384:THY01S_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRA6 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1123384:THY01S_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1123384:THY01S_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQV1 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1123384:THY01S_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRN5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1123384:THY01S_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1123384:THY01S_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A0X1KST1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1123384:THY01S_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1123384:THY01S_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPS7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPN4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/1123384:THY01S_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR14 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1123384:THY01S_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1123384:THY01S_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRT7 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1123384:THY01S_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR75 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1123384:THY01S_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1123384:THY01S_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS72 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1123384:THY01S_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRN1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1123384:THY01S_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPE6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1123384:THY01S_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1123384:THY01S_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1123384:THY01S_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQP5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1123384:THY01S_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT29 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1123384:THY01S_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS44 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1123384:THY01S_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQI1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQN8 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1123384:THY01S_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1123384:THY01S_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUK7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1123384:THY01S_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSD8 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1123384:THY01S_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ26 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Non-allosteric. http://togogenome.org/gene/1123384:THY01S_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1123384:THY01S_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTP1 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1123384:THY01S_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A0X1KUB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1123384:THY01S_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1123384:THY01S_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTE1 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1123384:THY01S_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR03 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1123384:THY01S_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1123384:THY01S_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1123384:THY01S_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP62 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1123384:THY01S_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQE2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1123384:THY01S_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP68 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1123384:THY01S_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1123384:THY01S_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ01 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1123384:THY01S_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRH4 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1123384:THY01S_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS69 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1123384:THY01S_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT42 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1123384:THY01S_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS99 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1123384:THY01S_RS07370 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1123384:THY01S_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A0X1KTT7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1123384:THY01S_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1123384:THY01S_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSU4 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1123384:THY01S_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQB4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1123384:THY01S_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1123384:THY01S_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPT4 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1123384:THY01S_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRL7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1123384:THY01S_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSN5 ^@ Function ^@ Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1123384:THY01S_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1123384:THY01S_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSH7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1123384:THY01S_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1123384:THY01S_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A0X1KP23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1123384:THY01S_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSY1 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1123384:THY01S_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1123384:THY01S_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1123384:THY01S_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1123384:THY01S_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1123384:THY01S_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSJ4 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1123384:THY01S_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT65 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1123384:THY01S_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ19 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1123384:THY01S_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1123384:THY01S_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS66 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1123384:THY01S_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0X1KPM4 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1123384:THY01S_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ65 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1123384:THY01S_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A0X1KR08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1123384:THY01S_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0X1KNT4 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1123384:THY01S_RS10225 ^@ http://purl.uniprot.org/uniprot/A0A0X1KT99 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1123384:THY01S_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1123384:THY01S_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A0X1KS70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A0X1KQ43 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1123384:THY01S_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1123384:THY01S_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A0X1KSS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1123384:THY01S_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0X1KRC9 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.