http://togogenome.org/gene/1196094:SALWKB2_RS11150 ^@ http://purl.uniprot.org/uniprot/X2H886 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1196094:SALWKB2_RS06555 ^@ http://purl.uniprot.org/uniprot/X2HBX6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1196094:SALWKB2_RS05010 ^@ http://purl.uniprot.org/uniprot/X2H4N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS01200 ^@ http://purl.uniprot.org/uniprot/X2H8Z0 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1196094:SALWKB2_RS08665 ^@ http://purl.uniprot.org/uniprot/X2HHV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10040 ^@ http://purl.uniprot.org/uniprot/X2HDV9 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS01330 ^@ http://purl.uniprot.org/uniprot/X2H993 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1196094:SALWKB2_RS00300 ^@ http://purl.uniprot.org/uniprot/X2H8F4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS08515 ^@ http://purl.uniprot.org/uniprot/X2HHQ8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/1196094:SALWKB2_RS07835 ^@ http://purl.uniprot.org/uniprot/X2HCL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06055 ^@ http://purl.uniprot.org/uniprot/X2HBM2 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03275 ^@ http://purl.uniprot.org/uniprot/X2HA35 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS03765 ^@ http://purl.uniprot.org/uniprot/X2H441 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/1196094:SALWKB2_RS09840 ^@ http://purl.uniprot.org/uniprot/X2HDY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04990 ^@ http://purl.uniprot.org/uniprot/X2H7H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08460 ^@ http://purl.uniprot.org/uniprot/X2H9L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/1196094:SALWKB2_RS06480 ^@ http://purl.uniprot.org/uniprot/X2HCA2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS03830 ^@ http://purl.uniprot.org/uniprot/X2HAH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/1196094:SALWKB2_RS06440 ^@ http://purl.uniprot.org/uniprot/X2HBV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09870 ^@ http://purl.uniprot.org/uniprot/X2HDR5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1196094:SALWKB2_RS01490 ^@ http://purl.uniprot.org/uniprot/X2H941 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1196094:SALWKB2_RS04430 ^@ http://purl.uniprot.org/uniprot/X2HB00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS09995 ^@ http://purl.uniprot.org/uniprot/X2H7H8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS08960 ^@ http://purl.uniprot.org/uniprot/X2HI17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS03630 ^@ http://purl.uniprot.org/uniprot/X2HAC0 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1196094:SALWKB2_RS06000 ^@ http://purl.uniprot.org/uniprot/X2HBK9 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS09185 ^@ http://purl.uniprot.org/uniprot/X2HDP9 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1196094:SALWKB2_RS00255 ^@ http://purl.uniprot.org/uniprot/X2H220 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS03455 ^@ http://purl.uniprot.org/uniprot/X2HA78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/1196094:SALWKB2_RS07990 ^@ http://purl.uniprot.org/uniprot/X2HD16 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS10730 ^@ http://purl.uniprot.org/uniprot/X2HED5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS12130 ^@ http://purl.uniprot.org/uniprot/X2HFJ9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1196094:SALWKB2_RS00245 ^@ http://purl.uniprot.org/uniprot/X2H8L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1196094:SALWKB2_RS08050 ^@ http://purl.uniprot.org/uniprot/X2HCR7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1196094:SALWKB2_RS08500 ^@ http://purl.uniprot.org/uniprot/X2HD30 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1196094:SALWKB2_RS06125 ^@ http://purl.uniprot.org/uniprot/X2HBP0 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1196094:SALWKB2_RS03410 ^@ http://purl.uniprot.org/uniprot/X2H3S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01435 ^@ http://purl.uniprot.org/uniprot/X2H9B0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1196094:SALWKB2_RS00430 ^@ http://purl.uniprot.org/uniprot/X2HD08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS02100 ^@ http://purl.uniprot.org/uniprot/X2H5S9 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/1196094:SALWKB2_RS02130 ^@ http://purl.uniprot.org/uniprot/X2H9M5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS06570 ^@ http://purl.uniprot.org/uniprot/X2HGK8 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS02850 ^@ http://purl.uniprot.org/uniprot/X2H3G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS10220 ^@ http://purl.uniprot.org/uniprot/X2H7L0 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS07815 ^@ http://purl.uniprot.org/uniprot/X2H685 ^@ Similarity ^@ Belongs to the N-Me-Phe pilin family. http://togogenome.org/gene/1196094:SALWKB2_RS11410 ^@ http://purl.uniprot.org/uniprot/X2HBD2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/1196094:SALWKB2_RS08885 ^@ http://purl.uniprot.org/uniprot/X2H706 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1196094:SALWKB2_RS06730 ^@ http://purl.uniprot.org/uniprot/X2HCE3 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/1196094:SALWKB2_RS10810 ^@ http://purl.uniprot.org/uniprot/X2H7Y9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1196094:SALWKB2_RS03935 ^@ http://purl.uniprot.org/uniprot/X2HAJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08010 ^@ http://purl.uniprot.org/uniprot/X2HHC4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1196094:SALWKB2_RS06155 ^@ http://purl.uniprot.org/uniprot/X2H5D6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS00450 ^@ http://purl.uniprot.org/uniprot/X2H250 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/1196094:SALWKB2_RS00065 ^@ http://purl.uniprot.org/uniprot/X2HCS1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1196094:SALWKB2_RS00980 ^@ http://purl.uniprot.org/uniprot/X2H904 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/1196094:SALWKB2_RS05035 ^@ http://purl.uniprot.org/uniprot/X2H4P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS04465 ^@ http://purl.uniprot.org/uniprot/X2HAS0 ^@ Function|||Similarity ^@ Belongs to the ClpA/ClpB family.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/1196094:SALWKB2_RS00115 ^@ http://purl.uniprot.org/uniprot/X2H8J2 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1196094:SALWKB2_RS06960 ^@ http://purl.uniprot.org/uniprot/X2HC35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03180 ^@ http://purl.uniprot.org/uniprot/X2HA82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06750 ^@ http://purl.uniprot.org/uniprot/X2HGN8 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1196094:SALWKB2_RS00080 ^@ http://purl.uniprot.org/uniprot/X2H1Y8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/1196094:SALWKB2_RS00825 ^@ http://purl.uniprot.org/uniprot/X2HD91 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS09855 ^@ http://purl.uniprot.org/uniprot/X2HAB7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1196094:SALWKB2_RS10785 ^@ http://purl.uniprot.org/uniprot/X2H7Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1196094:SALWKB2_RS09550 ^@ http://purl.uniprot.org/uniprot/X2HDV4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS03435 ^@ http://purl.uniprot.org/uniprot/X2H3T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01525 ^@ http://purl.uniprot.org/uniprot/X2HDQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02805 ^@ http://purl.uniprot.org/uniprot/X2H652 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1196094:SALWKB2_RS06150 ^@ http://purl.uniprot.org/uniprot/X2HBP7 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/1196094:SALWKB2_RS07360 ^@ http://purl.uniprot.org/uniprot/X2H8W9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS00755 ^@ http://purl.uniprot.org/uniprot/X2H8W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1196094:SALWKB2_RS07410 ^@ http://purl.uniprot.org/uniprot/X2H8X7 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10765 ^@ http://purl.uniprot.org/uniprot/X2HAX0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1196094:SALWKB2_RS01870 ^@ http://purl.uniprot.org/uniprot/X2H5M7 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1196094:SALWKB2_RS00445 ^@ http://purl.uniprot.org/uniprot/X2H8I7 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1196094:SALWKB2_RS09040 ^@ http://purl.uniprot.org/uniprot/X2HI24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05500 ^@ http://purl.uniprot.org/uniprot/X2HFV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1196094:SALWKB2_RS00395 ^@ http://purl.uniprot.org/uniprot/X2H243 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1196094:SALWKB2_RS01825 ^@ http://purl.uniprot.org/uniprot/X2HDV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05975 ^@ http://purl.uniprot.org/uniprot/X2HBK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS10670 ^@ http://purl.uniprot.org/uniprot/X2H7V5 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03960 ^@ http://purl.uniprot.org/uniprot/X2H472 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03670 ^@ http://purl.uniprot.org/uniprot/X2HAJ5 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS08695 ^@ http://purl.uniprot.org/uniprot/X2HDG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1196094:SALWKB2_RS03400 ^@ http://purl.uniprot.org/uniprot/X2HAD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1196094:SALWKB2_RS07030 ^@ http://purl.uniprot.org/uniprot/X2H8R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10280 ^@ http://purl.uniprot.org/uniprot/X2H7M3 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/1196094:SALWKB2_RS04660 ^@ http://purl.uniprot.org/uniprot/X2HAV3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1196094:SALWKB2_RS08480 ^@ http://purl.uniprot.org/uniprot/X2H6Q1 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1196094:SALWKB2_RS04150 ^@ http://purl.uniprot.org/uniprot/X2HAL7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1196094:SALWKB2_RS07155 ^@ http://purl.uniprot.org/uniprot/X2HC62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1196094:SALWKB2_RS03795 ^@ http://purl.uniprot.org/uniprot/X2HF12 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1196094:SALWKB2_RS08125 ^@ http://purl.uniprot.org/uniprot/X2H9B7 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS02785 ^@ http://purl.uniprot.org/uniprot/X2HEB5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1196094:SALWKB2_RS01455 ^@ http://purl.uniprot.org/uniprot/X2HDP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1196094:SALWKB2_RS07550 ^@ http://purl.uniprot.org/uniprot/X2HCR9 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/1196094:SALWKB2_RS07305 ^@ http://purl.uniprot.org/uniprot/X2H600 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1196094:SALWKB2_RS08180 ^@ http://purl.uniprot.org/uniprot/X2HD55 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/1196094:SALWKB2_RS02105 ^@ http://purl.uniprot.org/uniprot/X2HDZ8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1196094:SALWKB2_RS02515 ^@ http://purl.uniprot.org/uniprot/X2HE68 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/1196094:SALWKB2_RS09965 ^@ http://purl.uniprot.org/uniprot/X2H7G9 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1196094:SALWKB2_RS07040 ^@ http://purl.uniprot.org/uniprot/X2HCI8 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS03225 ^@ http://purl.uniprot.org/uniprot/X2HA93 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/1196094:SALWKB2_RS10680 ^@ http://purl.uniprot.org/uniprot/X2HIW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS00790 ^@ http://purl.uniprot.org/uniprot/X2H2C6 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1196094:SALWKB2_RS10780 ^@ http://purl.uniprot.org/uniprot/X2HEE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1196094:SALWKB2_RS07595 ^@ http://purl.uniprot.org/uniprot/X2HH36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1196094:SALWKB2_RS03235 ^@ http://purl.uniprot.org/uniprot/X2H6F2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01350 ^@ http://purl.uniprot.org/uniprot/X2HDN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS00105 ^@ http://purl.uniprot.org/uniprot/X2H4N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1196094:SALWKB2_RS00180 ^@ http://purl.uniprot.org/uniprot/X2H204 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1196094:SALWKB2_RS05335 ^@ http://purl.uniprot.org/uniprot/X2HB62 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1196094:SALWKB2_RS01850 ^@ http://purl.uniprot.org/uniprot/X2HDV3 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1196094:SALWKB2_RS00370 ^@ http://purl.uniprot.org/uniprot/X2H238 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS00185 ^@ http://purl.uniprot.org/uniprot/X2H4P9 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1196094:SALWKB2_RS04955 ^@ http://purl.uniprot.org/uniprot/X2HAZ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03430 ^@ http://purl.uniprot.org/uniprot/X2HA71 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS07530 ^@ http://purl.uniprot.org/uniprot/X2HCE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1196094:SALWKB2_RS03065 ^@ http://purl.uniprot.org/uniprot/X2H9X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00140 ^@ http://purl.uniprot.org/uniprot/X2H8J8 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/1196094:SALWKB2_RS07390 ^@ http://purl.uniprot.org/uniprot/X2HGZ4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1196094:SALWKB2_RS09035 ^@ http://purl.uniprot.org/uniprot/X2H9Z8 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS05965 ^@ http://purl.uniprot.org/uniprot/X2HG65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03140 ^@ http://purl.uniprot.org/uniprot/X2H3L4 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/1196094:SALWKB2_RS00365 ^@ http://purl.uniprot.org/uniprot/X2H8G8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS07985 ^@ http://purl.uniprot.org/uniprot/X2HHB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1196094:SALWKB2_RS07500 ^@ http://purl.uniprot.org/uniprot/X2HCD9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1196094:SALWKB2_RS06455 ^@ http://purl.uniprot.org/uniprot/X2HCA0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS01065 ^@ http://purl.uniprot.org/uniprot/X2H2J0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1196094:SALWKB2_RS09080 ^@ http://purl.uniprot.org/uniprot/X2H736 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS00390 ^@ http://purl.uniprot.org/uniprot/X2H8H5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS01130 ^@ http://purl.uniprot.org/uniprot/X2H936 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1196094:SALWKB2_RS05195 ^@ http://purl.uniprot.org/uniprot/X2H7K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/1196094:SALWKB2_RS01215 ^@ http://purl.uniprot.org/uniprot/X2H954 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/1196094:SALWKB2_RS05315 ^@ http://purl.uniprot.org/uniprot/X2H4T6 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1196094:SALWKB2_RS09020 ^@ http://purl.uniprot.org/uniprot/X2HDM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1196094:SALWKB2_RS09000 ^@ http://purl.uniprot.org/uniprot/X2H725 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1196094:SALWKB2_RS10710 ^@ http://purl.uniprot.org/uniprot/X2H7W5 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1196094:SALWKB2_RS04535 ^@ http://purl.uniprot.org/uniprot/X2HFD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01570 ^@ http://purl.uniprot.org/uniprot/X2HDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS03040 ^@ http://purl.uniprot.org/uniprot/X2H9W6 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS09210 ^@ http://purl.uniprot.org/uniprot/X2HDQ3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS01195 ^@ http://purl.uniprot.org/uniprot/X2H950 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/1196094:SALWKB2_RS05390 ^@ http://purl.uniprot.org/uniprot/X2H4V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04110 ^@ http://purl.uniprot.org/uniprot/X2H707 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1196094:SALWKB2_RS11450 ^@ http://purl.uniprot.org/uniprot/X2HEW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/1196094:SALWKB2_RS08575 ^@ http://purl.uniprot.org/uniprot/X2HD46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08650 ^@ http://purl.uniprot.org/uniprot/X2HD63 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1196094:SALWKB2_RS06620 ^@ http://purl.uniprot.org/uniprot/X2HCC6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS04240 ^@ http://purl.uniprot.org/uniprot/X2HAW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/1196094:SALWKB2_RS03710 ^@ http://purl.uniprot.org/uniprot/X2HAE2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1196094:SALWKB2_RS04370 ^@ http://purl.uniprot.org/uniprot/X2H758 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS05880 ^@ http://purl.uniprot.org/uniprot/X2H564 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1196094:SALWKB2_RS05330 ^@ http://purl.uniprot.org/uniprot/X2HBH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS06200 ^@ http://purl.uniprot.org/uniprot/X2HBQ7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1196094:SALWKB2_RS03700 ^@ http://purl.uniprot.org/uniprot/X2HEW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS01630 ^@ http://purl.uniprot.org/uniprot/X2H2V8 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS02300 ^@ http://purl.uniprot.org/uniprot/X2H9I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1196094:SALWKB2_RS09250 ^@ http://purl.uniprot.org/uniprot/X2HDR1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS03170 ^@ http://purl.uniprot.org/uniprot/X2H6D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08190 ^@ http://purl.uniprot.org/uniprot/X2H9D8 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1196094:SALWKB2_RS05770 ^@ http://purl.uniprot.org/uniprot/X2HG22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1196094:SALWKB2_RS06465 ^@ http://purl.uniprot.org/uniprot/X2H5L2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1196094:SALWKB2_RS06610 ^@ http://purl.uniprot.org/uniprot/X2H8K4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1196094:SALWKB2_RS00215 ^@ http://purl.uniprot.org/uniprot/X2HCV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10815 ^@ http://purl.uniprot.org/uniprot/X2HAY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1196094:SALWKB2_RS05960 ^@ http://purl.uniprot.org/uniprot/X2H853 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS01155 ^@ http://purl.uniprot.org/uniprot/X2H944 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS06060 ^@ http://purl.uniprot.org/uniprot/X2H5B2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS01430 ^@ http://purl.uniprot.org/uniprot/X2HDP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS08705 ^@ http://purl.uniprot.org/uniprot/X2H6V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS09160 ^@ http://purl.uniprot.org/uniprot/X2HDP3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS06130 ^@ http://purl.uniprot.org/uniprot/X2H5D0 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1196094:SALWKB2_RS06005 ^@ http://purl.uniprot.org/uniprot/X2H598 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1196094:SALWKB2_RS11060 ^@ http://purl.uniprot.org/uniprot/X2HJ78 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04035 ^@ http://purl.uniprot.org/uniprot/X2H6Z3 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS11430 ^@ http://purl.uniprot.org/uniprot/X2H8F0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1196094:SALWKB2_RS08005 ^@ http://purl.uniprot.org/uniprot/X2H984 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1196094:SALWKB2_RS00970 ^@ http://purl.uniprot.org/uniprot/X2H542 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1196094:SALWKB2_RS03485 ^@ http://purl.uniprot.org/uniprot/X2H3U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1196094:SALWKB2_RS10260 ^@ http://purl.uniprot.org/uniprot/X2H7L9 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/1196094:SALWKB2_RS08175 ^@ http://purl.uniprot.org/uniprot/X2HHG3 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role. http://togogenome.org/gene/1196094:SALWKB2_RS05365 ^@ http://purl.uniprot.org/uniprot/X2HB67 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS01385 ^@ http://purl.uniprot.org/uniprot/X2H2T1 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the group II decarboxylase family. http://togogenome.org/gene/1196094:SALWKB2_RS10770 ^@ http://purl.uniprot.org/uniprot/X2HIY2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1196094:SALWKB2_RS10445 ^@ http://purl.uniprot.org/uniprot/X2HEA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1196094:SALWKB2_RS03075 ^@ http://purl.uniprot.org/uniprot/X2H6A3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS07395 ^@ http://purl.uniprot.org/uniprot/X2HCN9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03640 ^@ http://purl.uniprot.org/uniprot/X2H6Q2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1196094:SALWKB2_RS05795 ^@ http://purl.uniprot.org/uniprot/X2HG27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS05170 ^@ http://purl.uniprot.org/uniprot/X2H7K4 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1196094:SALWKB2_RS08435 ^@ http://purl.uniprot.org/uniprot/X2H9K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/1196094:SALWKB2_RS10850 ^@ http://purl.uniprot.org/uniprot/X2HEJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS10755 ^@ http://purl.uniprot.org/uniprot/X2HEE3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS04280 ^@ http://purl.uniprot.org/uniprot/X2H742 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1196094:SALWKB2_RS08910 ^@ http://purl.uniprot.org/uniprot/X2HI11 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1196094:SALWKB2_RS08000 ^@ http://purl.uniprot.org/uniprot/X2H6C8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS06280 ^@ http://purl.uniprot.org/uniprot/X2HC66 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/1196094:SALWKB2_RS04120 ^@ http://purl.uniprot.org/uniprot/X2HAU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1196094:SALWKB2_RS10005 ^@ http://purl.uniprot.org/uniprot/X2HIH5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1196094:SALWKB2_RS08305 ^@ http://purl.uniprot.org/uniprot/X2H6K7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1196094:SALWKB2_RS10855 ^@ http://purl.uniprot.org/uniprot/X2HEH1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1196094:SALWKB2_RS06160 ^@ http://purl.uniprot.org/uniprot/X2H8A7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1196094:SALWKB2_RS02945 ^@ http://purl.uniprot.org/uniprot/X2H9U4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1196094:SALWKB2_RS00440 ^@ http://purl.uniprot.org/uniprot/X2H8Q7 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1196094:SALWKB2_RS02950 ^@ http://purl.uniprot.org/uniprot/X2H3I0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10270 ^@ http://purl.uniprot.org/uniprot/X2HIM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05395 ^@ http://purl.uniprot.org/uniprot/X2H7P0 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1196094:SALWKB2_RS10735 ^@ http://purl.uniprot.org/uniprot/X2H7X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/1196094:SALWKB2_RS04305 ^@ http://purl.uniprot.org/uniprot/X2H745 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1196094:SALWKB2_RS07230 ^@ http://purl.uniprot.org/uniprot/X2H5Z2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04000 ^@ http://purl.uniprot.org/uniprot/X2HAJ8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1196094:SALWKB2_RS10540 ^@ http://purl.uniprot.org/uniprot/X2H7S7 ^@ Similarity ^@ Belongs to the cytochrome b562 family. http://togogenome.org/gene/1196094:SALWKB2_RS11115 ^@ http://purl.uniprot.org/uniprot/X2HB58 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03905 ^@ http://purl.uniprot.org/uniprot/X2HF30 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1196094:SALWKB2_RS00160 ^@ http://purl.uniprot.org/uniprot/X2HCU5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1196094:SALWKB2_RS08260 ^@ http://purl.uniprot.org/uniprot/X2H6J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1196094:SALWKB2_RS05245 ^@ http://purl.uniprot.org/uniprot/X2H7L8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03245 ^@ http://purl.uniprot.org/uniprot/X2HA97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02275 ^@ http://purl.uniprot.org/uniprot/X2H9Q2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1196094:SALWKB2_RS07785 ^@ http://purl.uniprot.org/uniprot/X2HCK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS10210 ^@ http://purl.uniprot.org/uniprot/X2HE55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11420 ^@ http://purl.uniprot.org/uniprot/X2HEX5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS03965 ^@ http://purl.uniprot.org/uniprot/X2H6Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1196094:SALWKB2_RS01305 ^@ http://purl.uniprot.org/uniprot/X2H989 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1196094:SALWKB2_RS05815 ^@ http://purl.uniprot.org/uniprot/X2H810 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1196094:SALWKB2_RS03985 ^@ http://purl.uniprot.org/uniprot/X2H6Y5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1196094:SALWKB2_RS08015 ^@ http://purl.uniprot.org/uniprot/X2HD21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1196094:SALWKB2_RS08085 ^@ http://purl.uniprot.org/uniprot/X2HHE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1196094:SALWKB2_RS08710 ^@ http://purl.uniprot.org/uniprot/X2H9S5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1196094:SALWKB2_RS10880 ^@ http://purl.uniprot.org/uniprot/X2HEH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1196094:SALWKB2_RS08405 ^@ http://purl.uniprot.org/uniprot/X2H6N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1196094:SALWKB2_RS09865 ^@ http://purl.uniprot.org/uniprot/X2HDZ2 ^@ Similarity ^@ Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS01300 ^@ http://purl.uniprot.org/uniprot/X2HDM2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS11030 ^@ http://purl.uniprot.org/uniprot/X2HB37 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1196094:SALWKB2_RS05025 ^@ http://purl.uniprot.org/uniprot/X2HBA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1196094:SALWKB2_RS10580 ^@ http://purl.uniprot.org/uniprot/X2HE97 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. http://togogenome.org/gene/1196094:SALWKB2_RS09130 ^@ http://purl.uniprot.org/uniprot/X2HI35 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS07015 ^@ http://purl.uniprot.org/uniprot/X2HCI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03625 ^@ http://purl.uniprot.org/uniprot/X2HAI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS02905 ^@ http://purl.uniprot.org/uniprot/X2H671 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08855 ^@ http://purl.uniprot.org/uniprot/X2HDB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS07780 ^@ http://purl.uniprot.org/uniprot/X2HH73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10900 ^@ http://purl.uniprot.org/uniprot/X2HEK6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS09645 ^@ http://purl.uniprot.org/uniprot/X2HIB5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1196094:SALWKB2_RS00025 ^@ http://purl.uniprot.org/uniprot/X2H1X7 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1196094:SALWKB2_RS03950 ^@ http://purl.uniprot.org/uniprot/X2HF38 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1196094:SALWKB2_RS07225 ^@ http://purl.uniprot.org/uniprot/X2HC79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06515 ^@ http://purl.uniprot.org/uniprot/X2H5M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS05870 ^@ http://purl.uniprot.org/uniprot/X2HBV0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1196094:SALWKB2_RS07640 ^@ http://purl.uniprot.org/uniprot/X2HCU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06590 ^@ http://purl.uniprot.org/uniprot/X2H8K1 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1196094:SALWKB2_RS03750 ^@ http://purl.uniprot.org/uniprot/X2HEZ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1196094:SALWKB2_RS00410 ^@ http://purl.uniprot.org/uniprot/X2H8Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS09215 ^@ http://purl.uniprot.org/uniprot/X2HDG8 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1196094:SALWKB2_RS07975 ^@ http://purl.uniprot.org/uniprot/X2HCP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09990 ^@ http://purl.uniprot.org/uniprot/X2HE19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10940 ^@ http://purl.uniprot.org/uniprot/X2HB11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1196094:SALWKB2_RS01320 ^@ http://purl.uniprot.org/uniprot/X2H5E8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1196094:SALWKB2_RS09590 ^@ http://purl.uniprot.org/uniprot/X2H7B7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS09015 ^@ http://purl.uniprot.org/uniprot/X2HI19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02345 ^@ http://purl.uniprot.org/uniprot/X2H9R6 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1196094:SALWKB2_RS05680 ^@ http://purl.uniprot.org/uniprot/X2HBQ6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1196094:SALWKB2_RS04270 ^@ http://purl.uniprot.org/uniprot/X2HAN4 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/1196094:SALWKB2_RS03345 ^@ http://purl.uniprot.org/uniprot/X2H6H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00260 ^@ http://purl.uniprot.org/uniprot/X2H4R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00350 ^@ http://purl.uniprot.org/uniprot/X2H4S5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00765 ^@ http://purl.uniprot.org/uniprot/X2H2B4 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1196094:SALWKB2_RS10455 ^@ http://purl.uniprot.org/uniprot/X2H7Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1196094:SALWKB2_RS06800 ^@ http://purl.uniprot.org/uniprot/X2HGP8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS04360 ^@ http://purl.uniprot.org/uniprot/X2HAQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01745 ^@ http://purl.uniprot.org/uniprot/X2H5K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04180 ^@ http://purl.uniprot.org/uniprot/X2H4A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family.|||Periplasm http://togogenome.org/gene/1196094:SALWKB2_RS11075 ^@ http://purl.uniprot.org/uniprot/X2HJ85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinone-dependent D-lactate dehydrogenase family.|||Catalyzes the oxidation of D-lactate to pyruvate.|||Cell inner membrane http://togogenome.org/gene/1196094:SALWKB2_RS01090 ^@ http://purl.uniprot.org/uniprot/X2H2J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08045 ^@ http://purl.uniprot.org/uniprot/X2HD26 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS05760 ^@ http://purl.uniprot.org/uniprot/X2H533 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1196094:SALWKB2_RS00220 ^@ http://purl.uniprot.org/uniprot/X2H8L4 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS04025 ^@ http://purl.uniprot.org/uniprot/X2HAK1 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1196094:SALWKB2_RS03445 ^@ http://purl.uniprot.org/uniprot/X2HEQ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1196094:SALWKB2_RS11160 ^@ http://purl.uniprot.org/uniprot/X2HJB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Iron-storage protein.|||Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited. http://togogenome.org/gene/1196094:SALWKB2_RS08490 ^@ http://purl.uniprot.org/uniprot/X2HHP9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS07045 ^@ http://purl.uniprot.org/uniprot/X2HC45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS00785 ^@ http://purl.uniprot.org/uniprot/X2H8Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS01225 ^@ http://purl.uniprot.org/uniprot/X2H2M8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1196094:SALWKB2_RS00340 ^@ http://purl.uniprot.org/uniprot/X2H8G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06020 ^@ http://purl.uniprot.org/uniprot/X2HBZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1196094:SALWKB2_RS05730 ^@ http://purl.uniprot.org/uniprot/X2HBE1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS11205 ^@ http://purl.uniprot.org/uniprot/X2HET2 ^@ Similarity ^@ Belongs to the stealth family. http://togogenome.org/gene/1196094:SALWKB2_RS10840 ^@ http://purl.uniprot.org/uniprot/X2HAY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS06225 ^@ http://purl.uniprot.org/uniprot/X2HBR3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1196094:SALWKB2_RS02310 ^@ http://purl.uniprot.org/uniprot/X2H5X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1196094:SALWKB2_RS01120 ^@ http://purl.uniprot.org/uniprot/X2H587 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08880 ^@ http://purl.uniprot.org/uniprot/X2HDC2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1196094:SALWKB2_RS04145 ^@ http://purl.uniprot.org/uniprot/X2HAV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1196094:SALWKB2_RS10955 ^@ http://purl.uniprot.org/uniprot/X2HEJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS04235 ^@ http://purl.uniprot.org/uniprot/X2HF86 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1196094:SALWKB2_RS01325 ^@ http://purl.uniprot.org/uniprot/X2HDM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1196094:SALWKB2_RS00960 ^@ http://purl.uniprot.org/uniprot/X2H8T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08680 ^@ http://purl.uniprot.org/uniprot/X2H6U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1196094:SALWKB2_RS07505 ^@ http://purl.uniprot.org/uniprot/X2H634 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1196094:SALWKB2_RS00845 ^@ http://purl.uniprot.org/uniprot/X2H521 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05385 ^@ http://purl.uniprot.org/uniprot/X2HBI0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1196094:SALWKB2_RS08270 ^@ http://purl.uniprot.org/uniprot/X2HHI6 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1196094:SALWKB2_RS11495 ^@ http://purl.uniprot.org/uniprot/X2HCX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1196094:SALWKB2_RS01360 ^@ http://purl.uniprot.org/uniprot/X2H927 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS09070 ^@ http://purl.uniprot.org/uniprot/X2HDM8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS02090 ^@ http://purl.uniprot.org/uniprot/X2H9E0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1196094:SALWKB2_RS01780 ^@ http://purl.uniprot.org/uniprot/X2H9F9 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/1196094:SALWKB2_RS07445 ^@ http://purl.uniprot.org/uniprot/X2HCP9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS11480 ^@ http://purl.uniprot.org/uniprot/X2HJK2 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1196094:SALWKB2_RS01050 ^@ http://purl.uniprot.org/uniprot/X2H2I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1196094:SALWKB2_RS05650 ^@ http://purl.uniprot.org/uniprot/X2H7V3 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1196094:SALWKB2_RS01040 ^@ http://purl.uniprot.org/uniprot/X2H916 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00015 ^@ http://purl.uniprot.org/uniprot/X2H8H2 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/1196094:SALWKB2_RS08080 ^@ http://purl.uniprot.org/uniprot/X2H9A3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01800 ^@ http://purl.uniprot.org/uniprot/X2HDU5 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1196094:SALWKB2_RS10800 ^@ http://purl.uniprot.org/uniprot/X2HEI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS04455 ^@ http://purl.uniprot.org/uniprot/X2HFC5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS08450 ^@ http://purl.uniprot.org/uniprot/X2HD19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1196094:SALWKB2_RS04170 ^@ http://purl.uniprot.org/uniprot/X2HAV4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/1196094:SALWKB2_RS00955 ^@ http://purl.uniprot.org/uniprot/X2H8Z8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1196094:SALWKB2_RS00335 ^@ http://purl.uniprot.org/uniprot/X2H8N6 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/1196094:SALWKB2_RS00225 ^@ http://purl.uniprot.org/uniprot/X2H8E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08990 ^@ http://purl.uniprot.org/uniprot/X2HDL8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1196094:SALWKB2_RS05320 ^@ http://purl.uniprot.org/uniprot/X2H7M9 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1196094:SALWKB2_RS05980 ^@ http://purl.uniprot.org/uniprot/X2H591 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05605 ^@ http://purl.uniprot.org/uniprot/X2HFY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1196094:SALWKB2_RS05930 ^@ http://purl.uniprot.org/uniprot/X2H580 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1196094:SALWKB2_RS11050 ^@ http://purl.uniprot.org/uniprot/X2H857 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09955 ^@ http://purl.uniprot.org/uniprot/X2HE10 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS05165 ^@ http://purl.uniprot.org/uniprot/X2H4R0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1196094:SALWKB2_RS03150 ^@ http://purl.uniprot.org/uniprot/X2HEJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS06540 ^@ http://purl.uniprot.org/uniprot/X2H8J1 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1196094:SALWKB2_RS02835 ^@ http://purl.uniprot.org/uniprot/X2HEC6 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1196094:SALWKB2_RS01515 ^@ http://purl.uniprot.org/uniprot/X2H2U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06185 ^@ http://purl.uniprot.org/uniprot/X2H8B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1196094:SALWKB2_RS04885 ^@ http://purl.uniprot.org/uniprot/X2H4L7 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS01335 ^@ http://purl.uniprot.org/uniprot/X2H923 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1196094:SALWKB2_RS07555 ^@ http://purl.uniprot.org/uniprot/X2HCF2 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1196094:SALWKB2_RS08495 ^@ http://purl.uniprot.org/uniprot/X2HDB6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1196094:SALWKB2_RS10365 ^@ http://purl.uniprot.org/uniprot/X2HAK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS09960 ^@ http://purl.uniprot.org/uniprot/X2HDT5 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/1196094:SALWKB2_RS03120 ^@ http://purl.uniprot.org/uniprot/X2H6B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01445 ^@ http://purl.uniprot.org/uniprot/X2H2T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08120 ^@ http://purl.uniprot.org/uniprot/X2H6G1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS05150 ^@ http://purl.uniprot.org/uniprot/X2HFN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1196094:SALWKB2_RS10795 ^@ http://purl.uniprot.org/uniprot/X2HIZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1196094:SALWKB2_RS05830 ^@ http://purl.uniprot.org/uniprot/X2HBG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1196094:SALWKB2_RS05805 ^@ http://purl.uniprot.org/uniprot/X2HBG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01895 ^@ http://purl.uniprot.org/uniprot/X2H5N3 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1196094:SALWKB2_RS05580 ^@ http://purl.uniprot.org/uniprot/X2HFX4 ^@ Similarity ^@ Belongs to the DNA polymerase HolA subunit family. http://togogenome.org/gene/1196094:SALWKB2_RS10830 ^@ http://purl.uniprot.org/uniprot/X2HEG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1196094:SALWKB2_RS09910 ^@ http://purl.uniprot.org/uniprot/X2HIF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1196094:SALWKB2_RS00360 ^@ http://purl.uniprot.org/uniprot/X2H8P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS00060 ^@ http://purl.uniprot.org/uniprot/X2H4M7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS01950 ^@ http://purl.uniprot.org/uniprot/X2H9I7 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/1196094:SALWKB2_RS03930 ^@ http://purl.uniprot.org/uniprot/X2HAR5 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1196094:SALWKB2_RS00100 ^@ http://purl.uniprot.org/uniprot/X2H1Z1 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1196094:SALWKB2_RS05570 ^@ http://purl.uniprot.org/uniprot/X2H4Y7 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1196094:SALWKB2_RS03250 ^@ http://purl.uniprot.org/uniprot/X2HA29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1196094:SALWKB2_RS03735 ^@ http://purl.uniprot.org/uniprot/X2HAE9 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1196094:SALWKB2_RS07355 ^@ http://purl.uniprot.org/uniprot/X2H609 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03945 ^@ http://purl.uniprot.org/uniprot/X2H6X9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1196094:SALWKB2_RS06760 ^@ http://purl.uniprot.org/uniprot/X2HC04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS07980 ^@ http://purl.uniprot.org/uniprot/X2H979 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1196094:SALWKB2_RS08995 ^@ http://purl.uniprot.org/uniprot/X2HDD8 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS00740 ^@ http://purl.uniprot.org/uniprot/X2H2A8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS10435 ^@ http://purl.uniprot.org/uniprot/X2HAM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS02970 ^@ http://purl.uniprot.org/uniprot/X2H3I3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10825 ^@ http://purl.uniprot.org/uniprot/X2HEJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1196094:SALWKB2_RS04165 ^@ http://purl.uniprot.org/uniprot/X2HF74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1196094:SALWKB2_RS10465 ^@ http://purl.uniprot.org/uniprot/X2HIS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02840 ^@ http://purl.uniprot.org/uniprot/X2HA05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1196094:SALWKB2_RS03285 ^@ http://purl.uniprot.org/uniprot/X2H6G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00190 ^@ http://purl.uniprot.org/uniprot/X2HCV1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1196094:SALWKB2_RS02920 ^@ http://purl.uniprot.org/uniprot/X2H9T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11470 ^@ http://purl.uniprot.org/uniprot/X2H8F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/1196094:SALWKB2_RS00730 ^@ http://purl.uniprot.org/uniprot/X2H8V8 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1196094:SALWKB2_RS08600 ^@ http://purl.uniprot.org/uniprot/X2HD51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1196094:SALWKB2_RS05360 ^@ http://purl.uniprot.org/uniprot/X2HBH5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS09585 ^@ http://purl.uniprot.org/uniprot/X2HDV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1196094:SALWKB2_RS08975 ^@ http://purl.uniprot.org/uniprot/X2H721 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1196094:SALWKB2_RS09240 ^@ http://purl.uniprot.org/uniprot/X2H764 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS07710 ^@ http://purl.uniprot.org/uniprot/X2HH60 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1196094:SALWKB2_RS03460 ^@ http://purl.uniprot.org/uniprot/X2H3T9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS00125 ^@ http://purl.uniprot.org/uniprot/X2H1Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1196094:SALWKB2_RS03215 ^@ http://purl.uniprot.org/uniprot/X2H6E5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1196094:SALWKB2_RS08315 ^@ http://purl.uniprot.org/uniprot/X2HHK0 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1196094:SALWKB2_RS04385 ^@ http://purl.uniprot.org/uniprot/X2HAQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00735 ^@ http://purl.uniprot.org/uniprot/X2H8P4 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1196094:SALWKB2_RS02155 ^@ http://purl.uniprot.org/uniprot/X2H9F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1196094:SALWKB2_RS00235 ^@ http://purl.uniprot.org/uniprot/X2H4Q9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1196094:SALWKB2_RS02975 ^@ http://purl.uniprot.org/uniprot/X2H681 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS08895 ^@ http://purl.uniprot.org/uniprot/X2HI09 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1196094:SALWKB2_RS06205 ^@ http://purl.uniprot.org/uniprot/X2H5F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS10725 ^@ http://purl.uniprot.org/uniprot/X2HEG9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS06320 ^@ http://purl.uniprot.org/uniprot/X2H8G6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS09265 ^@ http://purl.uniprot.org/uniprot/X2HA34 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1196094:SALWKB2_RS06855 ^@ http://purl.uniprot.org/uniprot/X2HCG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10930 ^@ http://purl.uniprot.org/uniprot/X2HEJ2 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1196094:SALWKB2_RS03380 ^@ http://purl.uniprot.org/uniprot/X2HA61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08235 ^@ http://purl.uniprot.org/uniprot/X2H6J2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS02755 ^@ http://purl.uniprot.org/uniprot/X2H644 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/1196094:SALWKB2_RS10380 ^@ http://purl.uniprot.org/uniprot/X2HE38 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 104 family.|||Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes. http://togogenome.org/gene/1196094:SALWKB2_RS10805 ^@ http://purl.uniprot.org/uniprot/X2HEF6 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS06765 ^@ http://purl.uniprot.org/uniprot/X2H5Q9 ^@ Caution|||Function|||Similarity ^@ Belongs to the globin family.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03550 ^@ http://purl.uniprot.org/uniprot/X2HAG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1196094:SALWKB2_RS11535 ^@ http://purl.uniprot.org/uniprot/X2H9A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01240 ^@ http://purl.uniprot.org/uniprot/X2H961 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1196094:SALWKB2_RS03475 ^@ http://purl.uniprot.org/uniprot/X2HA84 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1196094:SALWKB2_RS03165 ^@ http://purl.uniprot.org/uniprot/X2H3L9 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS07525 ^@ http://purl.uniprot.org/uniprot/X2HCR5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS04125 ^@ http://purl.uniprot.org/uniprot/X2HAL5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS00165 ^@ http://purl.uniprot.org/uniprot/X2H8K3 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1196094:SALWKB2_RS04690 ^@ http://purl.uniprot.org/uniprot/X2H4I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS04285 ^@ http://purl.uniprot.org/uniprot/X2HF94 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1196094:SALWKB2_RS00010 ^@ http://purl.uniprot.org/uniprot/X2HCQ7 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1196094:SALWKB2_RS10205 ^@ http://purl.uniprot.org/uniprot/X2HIL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04555 ^@ http://purl.uniprot.org/uniprot/X2H790 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00400 ^@ http://purl.uniprot.org/uniprot/X2H4T8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS08475 ^@ http://purl.uniprot.org/uniprot/X2HD24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1196094:SALWKB2_RS06795 ^@ http://purl.uniprot.org/uniprot/X2H8N0 ^@ Similarity ^@ Belongs to the NAD synthetase family. http://togogenome.org/gene/1196094:SALWKB2_RS03055 ^@ http://purl.uniprot.org/uniprot/X2HEH2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS06785 ^@ http://purl.uniprot.org/uniprot/X2HC08 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1196094:SALWKB2_RS01635 ^@ http://purl.uniprot.org/uniprot/X2H9D9 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1196094:SALWKB2_RS07440 ^@ http://purl.uniprot.org/uniprot/X2HH03 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS04085 ^@ http://purl.uniprot.org/uniprot/X2H702 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1196094:SALWKB2_RS06140 ^@ http://purl.uniprot.org/uniprot/X2HGA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1196094:SALWKB2_RS06100 ^@ http://purl.uniprot.org/uniprot/X2HBN5 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1196094:SALWKB2_RS03760 ^@ http://purl.uniprot.org/uniprot/X2HAG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1196094:SALWKB2_RS08445 ^@ http://purl.uniprot.org/uniprot/X2HDA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02795 ^@ http://purl.uniprot.org/uniprot/X2H9R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10375 ^@ http://purl.uniprot.org/uniprot/X2HE90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1196094:SALWKB2_RS07470 ^@ http://purl.uniprot.org/uniprot/X2HCQ4 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS06115 ^@ http://purl.uniprot.org/uniprot/X2HGA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS07455 ^@ http://purl.uniprot.org/uniprot/X2H625 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS05000 ^@ http://purl.uniprot.org/uniprot/X2HB96 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1196094:SALWKB2_RS05345 ^@ http://purl.uniprot.org/uniprot/X2H7N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS00415 ^@ http://purl.uniprot.org/uniprot/X2H8I1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05895 ^@ http://purl.uniprot.org/uniprot/X2HBV6 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03110 ^@ http://purl.uniprot.org/uniprot/X2H9Y8 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1196094:SALWKB2_RS01880 ^@ http://purl.uniprot.org/uniprot/X2H9H6 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1196094:SALWKB2_RS04010 ^@ http://purl.uniprot.org/uniprot/X2H6Y9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1196094:SALWKB2_RS01315 ^@ http://purl.uniprot.org/uniprot/X2H2R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1196094:SALWKB2_RS04415 ^@ http://purl.uniprot.org/uniprot/X2H4E8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1196094:SALWKB2_RS05230 ^@ http://purl.uniprot.org/uniprot/X2HBE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01665 ^@ http://purl.uniprot.org/uniprot/X2H2W6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS10740 ^@ http://purl.uniprot.org/uniprot/X2HAW1 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1196094:SALWKB2_RS12140 ^@ http://purl.uniprot.org/uniprot/X2HE62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.|||Cell surface http://togogenome.org/gene/1196094:SALWKB2_RS05225 ^@ http://purl.uniprot.org/uniprot/X2HFP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS04060 ^@ http://purl.uniprot.org/uniprot/X2H6Z7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08385 ^@ http://purl.uniprot.org/uniprot/X2H9J3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS10075 ^@ http://purl.uniprot.org/uniprot/X2HAF7 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS07895 ^@ http://purl.uniprot.org/uniprot/X2H962 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Secreted http://togogenome.org/gene/1196094:SALWKB2_RS05625 ^@ http://purl.uniprot.org/uniprot/X2H7U8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1196094:SALWKB2_RS00545 ^@ http://purl.uniprot.org/uniprot/X2H4W3 ^@ Function|||Similarity ^@ Belongs to the ClpA/ClpB family.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/1196094:SALWKB2_RS05540 ^@ http://purl.uniprot.org/uniprot/X2HB93 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS06710 ^@ http://purl.uniprot.org/uniprot/X2HBZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08825 ^@ http://purl.uniprot.org/uniprot/X2HDJ9 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1196094:SALWKB2_RS07145 ^@ http://purl.uniprot.org/uniprot/X2HGV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1196094:SALWKB2_RS06595 ^@ http://purl.uniprot.org/uniprot/X2HGL1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1196094:SALWKB2_RS11185 ^@ http://purl.uniprot.org/uniprot/X2H8B2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS05455 ^@ http://purl.uniprot.org/uniprot/X2HB82 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1196094:SALWKB2_RS05205 ^@ http://purl.uniprot.org/uniprot/X2HBD9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS07105 ^@ http://purl.uniprot.org/uniprot/X2HC56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08930 ^@ http://purl.uniprot.org/uniprot/X2H9Y3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS03255 ^@ http://purl.uniprot.org/uniprot/X2H3N8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1196094:SALWKB2_RS02860 ^@ http://purl.uniprot.org/uniprot/X2HED2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07205 ^@ http://purl.uniprot.org/uniprot/X2H5Y7 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1196094:SALWKB2_RS08465 ^@ http://purl.uniprot.org/uniprot/X2HHP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1196094:SALWKB2_RS11440 ^@ http://purl.uniprot.org/uniprot/X2HJJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1196094:SALWKB2_RS07120 ^@ http://purl.uniprot.org/uniprot/X2H8T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1196094:SALWKB2_RS05070 ^@ http://purl.uniprot.org/uniprot/X2HFM8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS07775 ^@ http://purl.uniprot.org/uniprot/X2H938 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07580 ^@ http://purl.uniprot.org/uniprot/X2HCF7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1196094:SALWKB2_RS08420 ^@ http://purl.uniprot.org/uniprot/X2HDA0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS03650 ^@ http://purl.uniprot.org/uniprot/X2HAJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00205 ^@ http://purl.uniprot.org/uniprot/X2H210 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1196094:SALWKB2_RS01100 ^@ http://purl.uniprot.org/uniprot/X2HDF5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1196094:SALWKB2_RS07855 ^@ http://purl.uniprot.org/uniprot/X2HCL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01785 ^@ http://purl.uniprot.org/uniprot/X2H976 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1196094:SALWKB2_RS10180 ^@ http://purl.uniprot.org/uniprot/X2HIK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00760 ^@ http://purl.uniprot.org/uniprot/X2H8P9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1196094:SALWKB2_RS08645 ^@ http://purl.uniprot.org/uniprot/X2HDF3 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/1196094:SALWKB2_RS01205 ^@ http://purl.uniprot.org/uniprot/X2H5A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS05085 ^@ http://purl.uniprot.org/uniprot/X2H4Q3 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1196094:SALWKB2_RS11180 ^@ http://purl.uniprot.org/uniprot/X2HES2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/1196094:SALWKB2_RS07140 ^@ http://purl.uniprot.org/uniprot/X2H8T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS07475 ^@ http://purl.uniprot.org/uniprot/X2HCD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1196094:SALWKB2_RS05135 ^@ http://purl.uniprot.org/uniprot/X2H4Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04945 ^@ http://purl.uniprot.org/uniprot/X2HFK4 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1196094:SALWKB2_RS08595 ^@ http://purl.uniprot.org/uniprot/X2HDE0 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1196094:SALWKB2_RS00820 ^@ http://purl.uniprot.org/uniprot/X2H516 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08160 ^@ http://purl.uniprot.org/uniprot/X2HD50 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1196094:SALWKB2_RS01340 ^@ http://purl.uniprot.org/uniprot/X2H2S2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1196094:SALWKB2_RS03665 ^@ http://purl.uniprot.org/uniprot/X2HEV1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS05560 ^@ http://purl.uniprot.org/uniprot/X2HBM8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/1196094:SALWKB2_RS10750 ^@ http://purl.uniprot.org/uniprot/X2HEH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06845 ^@ http://purl.uniprot.org/uniprot/X2H8N7 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1196094:SALWKB2_RS06695 ^@ http://purl.uniprot.org/uniprot/X2H8L6 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1196094:SALWKB2_RS05545 ^@ http://purl.uniprot.org/uniprot/X2H4Y2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10595 ^@ http://purl.uniprot.org/uniprot/X2HIU8 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1196094:SALWKB2_RS06745 ^@ http://purl.uniprot.org/uniprot/X2H8M3 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS07490 ^@ http://purl.uniprot.org/uniprot/X2HH12 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1196094:SALWKB2_RS01890 ^@ http://purl.uniprot.org/uniprot/X2H2Z7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS06310 ^@ http://purl.uniprot.org/uniprot/X2HBU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/1196094:SALWKB2_RS09515 ^@ http://purl.uniprot.org/uniprot/X2HI94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1196094:SALWKB2_RS02055 ^@ http://purl.uniprot.org/uniprot/X2HDZ1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS07380 ^@ http://purl.uniprot.org/uniprot/X2H613 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1196094:SALWKB2_RS01675 ^@ http://purl.uniprot.org/uniprot/X2HDS9 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1196094:SALWKB2_RS02285 ^@ http://purl.uniprot.org/uniprot/X2H372 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1196094:SALWKB2_RS11265 ^@ http://purl.uniprot.org/uniprot/X2HJH4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1196094:SALWKB2_RS05675 ^@ http://purl.uniprot.org/uniprot/X2HFZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11445 ^@ http://purl.uniprot.org/uniprot/X2HEX8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS00005 ^@ http://purl.uniprot.org/uniprot/X2H1X2 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1196094:SALWKB2_RS01580 ^@ http://purl.uniprot.org/uniprot/X2H2V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10790 ^@ http://purl.uniprot.org/uniprot/X2HAX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1196094:SALWKB2_RS08025 ^@ http://purl.uniprot.org/uniprot/X2H6D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS07365 ^@ http://purl.uniprot.org/uniprot/X2HGZ0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09180 ^@ http://purl.uniprot.org/uniprot/X2HI42 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1196094:SALWKB2_RS10200 ^@ http://purl.uniprot.org/uniprot/X2HAH1 ^@ Cofactor ^@ Binds 1 phosphopantetheine covalently. http://togogenome.org/gene/1196094:SALWKB2_RS04485 ^@ http://purl.uniprot.org/uniprot/X2HB10 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1196094:SALWKB2_RS01685 ^@ http://purl.uniprot.org/uniprot/X2H968 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/1196094:SALWKB2_RS00380 ^@ http://purl.uniprot.org/uniprot/X2HCZ3 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1196094:SALWKB2_RS07310 ^@ http://purl.uniprot.org/uniprot/X2H8W2 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1196094:SALWKB2_RS07150 ^@ http://purl.uniprot.org/uniprot/X2HCK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1196094:SALWKB2_RS06075 ^@ http://purl.uniprot.org/uniprot/X2HC05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/1196094:SALWKB2_RS05380 ^@ http://purl.uniprot.org/uniprot/X2HFS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1196094:SALWKB2_RS00840 ^@ http://purl.uniprot.org/uniprot/X2H2E0 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS09925 ^@ http://purl.uniprot.org/uniprot/X2HAD0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03470 ^@ http://purl.uniprot.org/uniprot/X2HAF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS10520 ^@ http://purl.uniprot.org/uniprot/X2H7S1 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1196094:SALWKB2_RS11315 ^@ http://purl.uniprot.org/uniprot/X2HEW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1196094:SALWKB2_RS07090 ^@ http://purl.uniprot.org/uniprot/X2H8S9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1196094:SALWKB2_RS08505 ^@ http://purl.uniprot.org/uniprot/X2H6Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04005 ^@ http://purl.uniprot.org/uniprot/X2H481 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07585 ^@ http://purl.uniprot.org/uniprot/X2H646 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1196094:SALWKB2_RS02295 ^@ http://purl.uniprot.org/uniprot/X2H9Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/1196094:SALWKB2_RS08835 ^@ http://purl.uniprot.org/uniprot/X2H6Z9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1196094:SALWKB2_RS01125 ^@ http://purl.uniprot.org/uniprot/X2HDG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS01810 ^@ http://purl.uniprot.org/uniprot/X2H980 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS09125 ^@ http://purl.uniprot.org/uniprot/X2H744 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1196094:SALWKB2_RS02815 ^@ http://purl.uniprot.org/uniprot/X2H9Z9 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. http://togogenome.org/gene/1196094:SALWKB2_RS10430 ^@ http://purl.uniprot.org/uniprot/X2H7P7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1196094:SALWKB2_RS05835 ^@ http://purl.uniprot.org/uniprot/X2H552 ^@ Cofactor ^@ Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS10905 ^@ http://purl.uniprot.org/uniprot/X2HEI4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS00975 ^@ http://purl.uniprot.org/uniprot/X2HDB9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1196094:SALWKB2_RS01260 ^@ http://purl.uniprot.org/uniprot/X2H977 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1196094:SALWKB2_RS07800 ^@ http://purl.uniprot.org/uniprot/X2HH78 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1196094:SALWKB2_RS01010 ^@ http://purl.uniprot.org/uniprot/X2H553 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07035 ^@ http://purl.uniprot.org/uniprot/X2HGT8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/1196094:SALWKB2_RS05420 ^@ http://purl.uniprot.org/uniprot/X2HFT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08965 ^@ http://purl.uniprot.org/uniprot/X2HDL4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1196094:SALWKB2_RS03080 ^@ http://purl.uniprot.org/uniprot/X2HEH6 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/1196094:SALWKB2_RS07480 ^@ http://purl.uniprot.org/uniprot/X2H629 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1196094:SALWKB2_RS01165 ^@ http://purl.uniprot.org/uniprot/X2H2L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS07235 ^@ http://purl.uniprot.org/uniprot/X2H8V4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1196094:SALWKB2_RS07335 ^@ http://purl.uniprot.org/uniprot/X2H8W6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1196094:SALWKB2_RS01060 ^@ http://purl.uniprot.org/uniprot/X2H8W3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1196094:SALWKB2_RS07570 ^@ http://purl.uniprot.org/uniprot/X2HH32 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10460 ^@ http://purl.uniprot.org/uniprot/X2HAM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00420 ^@ http://purl.uniprot.org/uniprot/X2H247 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10495 ^@ http://purl.uniprot.org/uniprot/X2HEB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1196094:SALWKB2_RS02820 ^@ http://purl.uniprot.org/uniprot/X2H9S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/1196094:SALWKB2_RS03095 ^@ http://purl.uniprot.org/uniprot/X2H3K4 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1196094:SALWKB2_RS07760 ^@ http://purl.uniprot.org/uniprot/X2HCW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03405 ^@ http://purl.uniprot.org/uniprot/X2HA66 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1196094:SALWKB2_RS10895 ^@ http://purl.uniprot.org/uniprot/X2HJ22 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1196094:SALWKB2_RS07160 ^@ http://purl.uniprot.org/uniprot/X2H5X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/1196094:SALWKB2_RS11000 ^@ http://purl.uniprot.org/uniprot/X2HEM8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1196094:SALWKB2_RS01370 ^@ http://purl.uniprot.org/uniprot/X2H5F6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1196094:SALWKB2_RS06330 ^@ http://purl.uniprot.org/uniprot/X2HC81 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS08740 ^@ http://purl.uniprot.org/uniprot/X2HHX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1196094:SALWKB2_RS05695 ^@ http://purl.uniprot.org/uniprot/X2H7W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/1196094:SALWKB2_RS11355 ^@ http://purl.uniprot.org/uniprot/X2HBC5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS04860 ^@ http://purl.uniprot.org/uniprot/X2H4L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS04400 ^@ http://purl.uniprot.org/uniprot/X2HFB6 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. http://togogenome.org/gene/1196094:SALWKB2_RS01530 ^@ http://purl.uniprot.org/uniprot/X2H9C1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/1196094:SALWKB2_RS05735 ^@ http://purl.uniprot.org/uniprot/X2H527 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS08430 ^@ http://purl.uniprot.org/uniprot/X2H6N7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10640 ^@ http://purl.uniprot.org/uniprot/X2HAT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05370 ^@ http://purl.uniprot.org/uniprot/X2H4V0 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1196094:SALWKB2_RS10295 ^@ http://purl.uniprot.org/uniprot/X2HE13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08210 ^@ http://purl.uniprot.org/uniprot/X2H6I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS10305 ^@ http://purl.uniprot.org/uniprot/X2HAJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1196094:SALWKB2_RS06735 ^@ http://purl.uniprot.org/uniprot/X2HC01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0761 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08820 ^@ http://purl.uniprot.org/uniprot/X2HI02 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/1196094:SALWKB2_RS06875 ^@ http://purl.uniprot.org/uniprot/X2HGR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1196094:SALWKB2_RS02775 ^@ http://purl.uniprot.org/uniprot/X2H3E8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS06230 ^@ http://purl.uniprot.org/uniprot/X2H5F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08155 ^@ http://purl.uniprot.org/uniprot/X2HHF8 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1196094:SALWKB2_RS05260 ^@ http://purl.uniprot.org/uniprot/X2HB50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07170 ^@ http://purl.uniprot.org/uniprot/X2HGW0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters. http://togogenome.org/gene/1196094:SALWKB2_RS08280 ^@ http://purl.uniprot.org/uniprot/X2H6K3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS04650 ^@ http://purl.uniprot.org/uniprot/X2H7A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1196094:SALWKB2_RS04380 ^@ http://purl.uniprot.org/uniprot/X2HAZ2 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS04230 ^@ http://purl.uniprot.org/uniprot/X2H730 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1196094:SALWKB2_RS08265 ^@ http://purl.uniprot.org/uniprot/X2H9G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04175 ^@ http://purl.uniprot.org/uniprot/X2HAM1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05295 ^@ http://purl.uniprot.org/uniprot/X2H7M6 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS08920 ^@ http://purl.uniprot.org/uniprot/X2HDC9 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS08330 ^@ http://purl.uniprot.org/uniprot/X2H6L3 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/1196094:SALWKB2_RS10010 ^@ http://purl.uniprot.org/uniprot/X2HE24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1196094:SALWKB2_RS01380 ^@ http://purl.uniprot.org/uniprot/X2H930 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS01590 ^@ http://purl.uniprot.org/uniprot/X2HDR3 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03775 ^@ http://purl.uniprot.org/uniprot/X2HF08 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/1196094:SALWKB2_RS08565 ^@ http://purl.uniprot.org/uniprot/X2HHS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09140 ^@ http://purl.uniprot.org/uniprot/X2HDF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07685 ^@ http://purl.uniprot.org/uniprot/X2HH54 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1196094:SALWKB2_RS04195 ^@ http://purl.uniprot.org/uniprot/X2HAV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/1196094:SALWKB2_RS07060 ^@ http://purl.uniprot.org/uniprot/X2HC49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1196094:SALWKB2_RS01790 ^@ http://purl.uniprot.org/uniprot/X2H2Y1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1196094:SALWKB2_RS06830 ^@ http://purl.uniprot.org/uniprot/X2HCF6 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS09120 ^@ http://purl.uniprot.org/uniprot/X2HDF4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS06545 ^@ http://purl.uniprot.org/uniprot/X2HGK2 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1196094:SALWKB2_RS04340 ^@ http://purl.uniprot.org/uniprot/X2HAY4 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS03500 ^@ http://purl.uniprot.org/uniprot/X2HA89 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/1196094:SALWKB2_RS07175 ^@ http://purl.uniprot.org/uniprot/X2HCK7 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1196094:SALWKB2_RS04665 ^@ http://purl.uniprot.org/uniprot/X2H4I5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1196094:SALWKB2_RS08775 ^@ http://purl.uniprot.org/uniprot/X2H6Z1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS04020 ^@ http://purl.uniprot.org/uniprot/X2HAS9 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1196094:SALWKB2_RS03690 ^@ http://purl.uniprot.org/uniprot/X2HAD6 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1196094:SALWKB2_RS10820 ^@ http://purl.uniprot.org/uniprot/X2HIZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1196094:SALWKB2_RS06995 ^@ http://purl.uniprot.org/uniprot/X2H5U9 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1196094:SALWKB2_RS00095 ^@ http://purl.uniprot.org/uniprot/X2H8C1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1196094:SALWKB2_RS03340 ^@ http://purl.uniprot.org/uniprot/X2H3Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04790 ^@ http://purl.uniprot.org/uniprot/X2H4K1 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1196094:SALWKB2_RS03555 ^@ http://purl.uniprot.org/uniprot/X2HAA3 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1196094:SALWKB2_RS05495 ^@ http://purl.uniprot.org/uniprot/X2H7R0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1196094:SALWKB2_RS05565 ^@ http://purl.uniprot.org/uniprot/X2HB99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1196094:SALWKB2_RS05985 ^@ http://purl.uniprot.org/uniprot/X2H861 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09850 ^@ http://purl.uniprot.org/uniprot/X2H7F1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1196094:SALWKB2_RS04215 ^@ http://purl.uniprot.org/uniprot/X2HF82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1196094:SALWKB2_RS08720 ^@ http://purl.uniprot.org/uniprot/X2HDH0 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1196094:SALWKB2_RS06235 ^@ http://purl.uniprot.org/uniprot/X2H8D1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1196094:SALWKB2_RS06500 ^@ http://purl.uniprot.org/uniprot/X2HGJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01865 ^@ http://purl.uniprot.org/uniprot/X2H2Z3 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/1196094:SALWKB2_RS08675 ^@ http://purl.uniprot.org/uniprot/X2HD68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1196094:SALWKB2_RS04910 ^@ http://purl.uniprot.org/uniprot/X2H4M1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS00030 ^@ http://purl.uniprot.org/uniprot/X2H4M2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1196094:SALWKB2_RS04155 ^@ http://purl.uniprot.org/uniprot/X2H4A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS08285 ^@ http://purl.uniprot.org/uniprot/X2H9G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS00405 ^@ http://purl.uniprot.org/uniprot/X2HCZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS03685 ^@ http://purl.uniprot.org/uniprot/X2HAK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08690 ^@ http://purl.uniprot.org/uniprot/X2HHV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS06955 ^@ http://purl.uniprot.org/uniprot/X2HCH7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03955 ^@ http://purl.uniprot.org/uniprot/X2HAR8 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/1196094:SALWKB2_RS06220 ^@ http://purl.uniprot.org/uniprot/X2HC40 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/1196094:SALWKB2_RS06820 ^@ http://purl.uniprot.org/uniprot/X2H8N4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1196094:SALWKB2_RS06605 ^@ http://purl.uniprot.org/uniprot/X2HBY1 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1196094:SALWKB2_RS10835 ^@ http://purl.uniprot.org/uniprot/X2H7Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1196094:SALWKB2_RS01310 ^@ http://purl.uniprot.org/uniprot/X2H921 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1196094:SALWKB2_RS10300 ^@ http://purl.uniprot.org/uniprot/X2H7M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10565 ^@ http://purl.uniprot.org/uniprot/X2HAR3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS07925 ^@ http://purl.uniprot.org/uniprot/X2HD01 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS04480 ^@ http://purl.uniprot.org/uniprot/X2HFC8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1196094:SALWKB2_RS01220 ^@ http://purl.uniprot.org/uniprot/X2H8Z5 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1196094:SALWKB2_RS09580 ^@ http://purl.uniprot.org/uniprot/X2HIA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08535 ^@ http://purl.uniprot.org/uniprot/X2HHR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS07350 ^@ http://purl.uniprot.org/uniprot/X2HCA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05300 ^@ http://purl.uniprot.org/uniprot/X2HFR3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1196094:SALWKB2_RS01750 ^@ http://purl.uniprot.org/uniprot/X2HDT8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS03835 ^@ http://purl.uniprot.org/uniprot/X2H454 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01390 ^@ http://purl.uniprot.org/uniprot/X2H5G0 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1196094:SALWKB2_RS08205 ^@ http://purl.uniprot.org/uniprot/X2HCW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1196094:SALWKB2_RS04190 ^@ http://purl.uniprot.org/uniprot/X2HF78 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS01940 ^@ http://purl.uniprot.org/uniprot/X2H5P3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1196094:SALWKB2_RS05080 ^@ http://purl.uniprot.org/uniprot/X2HB22 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS03175 ^@ http://purl.uniprot.org/uniprot/X2HEJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1196094:SALWKB2_RS11330 ^@ http://purl.uniprot.org/uniprot/X2HBC2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1196094:SALWKB2_RS05585 ^@ http://purl.uniprot.org/uniprot/X2HBN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/1196094:SALWKB2_RS03850 ^@ http://purl.uniprot.org/uniprot/X2HAQ4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/1196094:SALWKB2_RS02780 ^@ http://purl.uniprot.org/uniprot/X2H647 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1196094:SALWKB2_RS06560 ^@ http://purl.uniprot.org/uniprot/X2H5M8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1196094:SALWKB2_RS01615 ^@ http://purl.uniprot.org/uniprot/X2HDR7 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/1196094:SALWKB2_RS10020 ^@ http://purl.uniprot.org/uniprot/X2H7I2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1196094:SALWKB2_RS09630 ^@ http://purl.uniprot.org/uniprot/X2HDM4 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/1196094:SALWKB2_RS01535 ^@ http://purl.uniprot.org/uniprot/X2H2U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1196094:SALWKB2_RS05175 ^@ http://purl.uniprot.org/uniprot/X2HFP2 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/1196094:SALWKB2_RS08400 ^@ http://purl.uniprot.org/uniprot/X2HD07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1196094:SALWKB2_RS04540 ^@ http://purl.uniprot.org/uniprot/X2HB20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08350 ^@ http://purl.uniprot.org/uniprot/X2HCZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11035 ^@ http://purl.uniprot.org/uniprot/X2HJ71 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS10910 ^@ http://purl.uniprot.org/uniprot/X2H820 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS01760 ^@ http://purl.uniprot.org/uniprot/X2H972 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS11325 ^@ http://purl.uniprot.org/uniprot/X2H8D8 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/1196094:SALWKB2_RS09635 ^@ http://purl.uniprot.org/uniprot/X2H7C4 ^@ Function|||Similarity ^@ Belongs to the UbiT family.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor. http://togogenome.org/gene/1196094:SALWKB2_RS07115 ^@ http://purl.uniprot.org/uniprot/X2H5W9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1196094:SALWKB2_RS04245 ^@ http://purl.uniprot.org/uniprot/X2HAN1 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1196094:SALWKB2_RS08540 ^@ http://purl.uniprot.org/uniprot/X2HDC7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1196094:SALWKB2_RS01680 ^@ http://purl.uniprot.org/uniprot/X2H9E7 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/1196094:SALWKB2_RS05950 ^@ http://purl.uniprot.org/uniprot/X2HBJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01080 ^@ http://purl.uniprot.org/uniprot/X2H925 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03320 ^@ http://purl.uniprot.org/uniprot/X2H6H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS08510 ^@ http://purl.uniprot.org/uniprot/X2H9M7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS02350 ^@ http://purl.uniprot.org/uniprot/X2H9J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1196094:SALWKB2_RS08135 ^@ http://purl.uniprot.org/uniprot/X2HD47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11465 ^@ http://purl.uniprot.org/uniprot/X2HJJ8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03885 ^@ http://purl.uniprot.org/uniprot/X2HAQ8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03375 ^@ http://purl.uniprot.org/uniprot/X2HAC5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS02765 ^@ http://purl.uniprot.org/uniprot/X2H9Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07905 ^@ http://purl.uniprot.org/uniprot/X2HCZ5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS10015 ^@ http://purl.uniprot.org/uniprot/X2HDV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1196094:SALWKB2_RS10745 ^@ http://purl.uniprot.org/uniprot/X2HIX8 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1196094:SALWKB2_RS00375 ^@ http://purl.uniprot.org/uniprot/X2H4T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS10070 ^@ http://purl.uniprot.org/uniprot/X2H7J0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1196094:SALWKB2_RS09030 ^@ http://purl.uniprot.org/uniprot/X2H729 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1196094:SALWKB2_RS03090 ^@ http://purl.uniprot.org/uniprot/X2H9X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS07435 ^@ http://purl.uniprot.org/uniprot/X2H8Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/1196094:SALWKB2_RS07315 ^@ http://purl.uniprot.org/uniprot/X2HGY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08070 ^@ http://purl.uniprot.org/uniprot/X2HCS3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1196094:SALWKB2_RS00945 ^@ http://purl.uniprot.org/uniprot/X2H536 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS07825 ^@ http://purl.uniprot.org/uniprot/X2HH81 ^@ Similarity ^@ Belongs to the N-Me-Phe pilin family. http://togogenome.org/gene/1196094:SALWKB2_RS07250 ^@ http://purl.uniprot.org/uniprot/X2HC85 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1196094:SALWKB2_RS06850 ^@ http://purl.uniprot.org/uniprot/X2HGQ7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/1196094:SALWKB2_RS10870 ^@ http://purl.uniprot.org/uniprot/X2HJ13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1196094:SALWKB2_RS04015 ^@ http://purl.uniprot.org/uniprot/X2HF48 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/1196094:SALWKB2_RS00935 ^@ http://purl.uniprot.org/uniprot/X2H8T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1196094:SALWKB2_RS01355 ^@ http://purl.uniprot.org/uniprot/X2H998 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1196094:SALWKB2_RS06135 ^@ http://purl.uniprot.org/uniprot/X2H8A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07405 ^@ http://purl.uniprot.org/uniprot/X2H617 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1196094:SALWKB2_RS08470 ^@ http://purl.uniprot.org/uniprot/X2HDA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS08760 ^@ http://purl.uniprot.org/uniprot/X2HHZ3 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1196094:SALWKB2_RS04065 ^@ http://purl.uniprot.org/uniprot/X2HF58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00150 ^@ http://purl.uniprot.org/uniprot/X2H200 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1196094:SALWKB2_RS07065 ^@ http://purl.uniprot.org/uniprot/X2H5W0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS10875 ^@ http://purl.uniprot.org/uniprot/X2HEK1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1196094:SALWKB2_RS08455 ^@ http://purl.uniprot.org/uniprot/X2H6P4 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS03655 ^@ http://purl.uniprot.org/uniprot/X2HAC8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS09970 ^@ http://purl.uniprot.org/uniprot/X2HAD7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS06950 ^@ http://purl.uniprot.org/uniprot/X2HGS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS04210 ^@ http://purl.uniprot.org/uniprot/X2H726 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1196094:SALWKB2_RS03990 ^@ http://purl.uniprot.org/uniprot/X2HF45 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1196094:SALWKB2_RS11020 ^@ http://purl.uniprot.org/uniprot/X2HJ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10440 ^@ http://purl.uniprot.org/uniprot/X2HIR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1196094:SALWKB2_RS03350 ^@ http://purl.uniprot.org/uniprot/X2HEN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01670 ^@ http://purl.uniprot.org/uniprot/X2H5J6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS03790 ^@ http://purl.uniprot.org/uniprot/X2H6V9 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1196094:SALWKB2_RS08850 ^@ http://purl.uniprot.org/uniprot/X2HDK1 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS06705 ^@ http://purl.uniprot.org/uniprot/X2HCD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00085 ^@ http://purl.uniprot.org/uniprot/X2H4N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/1196094:SALWKB2_RS04680 ^@ http://purl.uniprot.org/uniprot/X2HB46 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS08255 ^@ http://purl.uniprot.org/uniprot/X2HCX2 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1196094:SALWKB2_RS06575 ^@ http://purl.uniprot.org/uniprot/X2HCC0 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1196094:SALWKB2_RS02225 ^@ http://purl.uniprot.org/uniprot/X2H9P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07715 ^@ http://purl.uniprot.org/uniprot/X2HCV8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1196094:SALWKB2_RS05635 ^@ http://purl.uniprot.org/uniprot/X2HBP6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1196094:SALWKB2_RS01110 ^@ http://purl.uniprot.org/uniprot/X2H8X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS01915 ^@ http://purl.uniprot.org/uniprot/X2H301 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10720 ^@ http://purl.uniprot.org/uniprot/X2HIX3 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1196094:SALWKB2_RS02095 ^@ http://purl.uniprot.org/uniprot/X2H338 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1196094:SALWKB2_RS08955 ^@ http://purl.uniprot.org/uniprot/X2H9Y6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS00965 ^@ http://purl.uniprot.org/uniprot/X2H2G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS12395 ^@ http://purl.uniprot.org/uniprot/X2HDN9 ^@ Subcellular Location Annotation ^@ target cell cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS07245 ^@ http://purl.uniprot.org/uniprot/X2HCL7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1196094:SALWKB2_RS00240 ^@ http://purl.uniprot.org/uniprot/X2HCW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1196094:SALWKB2_RS07665 ^@ http://purl.uniprot.org/uniprot/X2HCU7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS01045 ^@ http://purl.uniprot.org/uniprot/X2H8V7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1196094:SALWKB2_RS06485 ^@ http://purl.uniprot.org/uniprot/X2HBW5 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS04655 ^@ http://purl.uniprot.org/uniprot/X2HFF4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1196094:SALWKB2_RS08020 ^@ http://purl.uniprot.org/uniprot/X2HCR1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1196094:SALWKB2_RS04470 ^@ http://purl.uniprot.org/uniprot/X2H4F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06300 ^@ http://purl.uniprot.org/uniprot/X2HGG9 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1196094:SALWKB2_RS04870 ^@ http://purl.uniprot.org/uniprot/X2HFJ0 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1196094:SALWKB2_RS07845 ^@ http://purl.uniprot.org/uniprot/X2HH86 ^@ Similarity ^@ Belongs to the SIP oxidoreductase family. http://togogenome.org/gene/1196094:SALWKB2_RS08685 ^@ http://purl.uniprot.org/uniprot/X2H9R8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS06175 ^@ http://purl.uniprot.org/uniprot/X2HBQ2 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1196094:SALWKB2_RS03515 ^@ http://purl.uniprot.org/uniprot/X2HES1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1196094:SALWKB2_RS03050 ^@ http://purl.uniprot.org/uniprot/X2H696 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1196094:SALWKB2_RS05520 ^@ http://purl.uniprot.org/uniprot/X2H4X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1196094:SALWKB2_RS00120 ^@ http://purl.uniprot.org/uniprot/X2H8C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS05850 ^@ http://purl.uniprot.org/uniprot/X2HBH7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS05405 ^@ http://purl.uniprot.org/uniprot/X2HBI6 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1196094:SALWKB2_RS03425 ^@ http://purl.uniprot.org/uniprot/X2HAD9 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1196094:SALWKB2_RS10915 ^@ http://purl.uniprot.org/uniprot/X2HB06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS03535 ^@ http://purl.uniprot.org/uniprot/X2H6M8 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS07625 ^@ http://purl.uniprot.org/uniprot/X2H655 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS00250 ^@ http://purl.uniprot.org/uniprot/X2H8E8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1196094:SALWKB2_RS09110 ^@ http://purl.uniprot.org/uniprot/X2HI32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/1196094:SALWKB2_RS11365 ^@ http://purl.uniprot.org/uniprot/X2HEW9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS11580 ^@ http://purl.uniprot.org/uniprot/X2HEL0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/1196094:SALWKB2_RS10890 ^@ http://purl.uniprot.org/uniprot/X2HB01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1196094:SALWKB2_RS05750 ^@ http://purl.uniprot.org/uniprot/X2HBS4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS00490 ^@ http://purl.uniprot.org/uniprot/X2H8J3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1196094:SALWKB2_RS01540 ^@ http://purl.uniprot.org/uniprot/X2H5H4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1196094:SALWKB2_RS06085 ^@ http://purl.uniprot.org/uniprot/X2H5B9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS07915 ^@ http://purl.uniprot.org/uniprot/X2H965 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11320 ^@ http://purl.uniprot.org/uniprot/X2HEU8 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/1196094:SALWKB2_RS06240 ^@ http://purl.uniprot.org/uniprot/X2HGD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS04100 ^@ http://purl.uniprot.org/uniprot/X2HAL3 ^@ Cofactor|||Similarity ^@ Belongs to the Nudix hydrolase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1196094:SALWKB2_RS03155 ^@ http://purl.uniprot.org/uniprot/X2HA77 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1196094:SALWKB2_RS03085 ^@ http://purl.uniprot.org/uniprot/X2HA62 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1196094:SALWKB2_RS12345 ^@ http://purl.uniprot.org/uniprot/X2H7Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS02280 ^@ http://purl.uniprot.org/uniprot/X2H9I0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1196094:SALWKB2_RS05055 ^@ http://purl.uniprot.org/uniprot/X2HB18 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1196094:SALWKB2_RS01115 ^@ http://purl.uniprot.org/uniprot/X2H2K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1196094:SALWKB2_RS10705 ^@ http://purl.uniprot.org/uniprot/X2HED0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS04075 ^@ http://purl.uniprot.org/uniprot/X2HAK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08360 ^@ http://purl.uniprot.org/uniprot/X2H9I6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/1196094:SALWKB2_RS04335 ^@ http://purl.uniprot.org/uniprot/X2HFA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1196094:SALWKB2_RS05910 ^@ http://purl.uniprot.org/uniprot/X2H840 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1196094:SALWKB2_RS01425 ^@ http://purl.uniprot.org/uniprot/X2H5G3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1196094:SALWKB2_RS02270 ^@ http://purl.uniprot.org/uniprot/X2HE28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS05215 ^@ http://purl.uniprot.org/uniprot/X2H4R8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1196094:SALWKB2_RS06815 ^@ http://purl.uniprot.org/uniprot/X2H5R8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1196094:SALWKB2_RS02315 ^@ http://purl.uniprot.org/uniprot/X2HE39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1196094:SALWKB2_RS02115 ^@ http://purl.uniprot.org/uniprot/X2H343 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS01765 ^@ http://purl.uniprot.org/uniprot/X2H2X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00795 ^@ http://purl.uniprot.org/uniprot/X2H510 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1196094:SALWKB2_RS00020 ^@ http://purl.uniprot.org/uniprot/X2H8B0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS10450 ^@ http://purl.uniprot.org/uniprot/X2HE61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1196094:SALWKB2_RS06010 ^@ http://purl.uniprot.org/uniprot/X2H866 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS10030 ^@ http://purl.uniprot.org/uniprot/X2HII1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1196094:SALWKB2_RS11295 ^@ http://purl.uniprot.org/uniprot/X2HEU5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1196094:SALWKB2_RS06655 ^@ http://purl.uniprot.org/uniprot/X2H8K9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1196094:SALWKB2_RS11605 ^@ http://purl.uniprot.org/uniprot/X2HAS8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1196094:SALWKB2_RS04395 ^@ http://purl.uniprot.org/uniprot/X2H762 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1196094:SALWKB2_RS07260 ^@ http://purl.uniprot.org/uniprot/X2H8V9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1196094:SALWKB2_RS03820 ^@ http://purl.uniprot.org/uniprot/X2HF17 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1196094:SALWKB2_RS05115 ^@ http://purl.uniprot.org/uniprot/X2HBC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1196094:SALWKB2_RS10490 ^@ http://purl.uniprot.org/uniprot/X2HIS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1196094:SALWKB2_RS03610 ^@ http://purl.uniprot.org/uniprot/X2H3X8 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1196094:SALWKB2_RS11110 ^@ http://purl.uniprot.org/uniprot/X2H875 ^@ Cofactor|||Function|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. http://togogenome.org/gene/1196094:SALWKB2_RS08055 ^@ http://purl.uniprot.org/uniprot/X2H996 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11055 ^@ http://purl.uniprot.org/uniprot/X2HB43 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1196094:SALWKB2_RS00090 ^@ http://purl.uniprot.org/uniprot/X2H8I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01290 ^@ http://purl.uniprot.org/uniprot/X2H998 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1196094:SALWKB2_RS06335 ^@ http://purl.uniprot.org/uniprot/X2HBU7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1196094:SALWKB2_RS10865 ^@ http://purl.uniprot.org/uniprot/X2HAZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1196094:SALWKB2_RS08090 ^@ http://purl.uniprot.org/uniprot/X2HD39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1196094:SALWKB2_RS05630 ^@ http://purl.uniprot.org/uniprot/X2HFY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1196094:SALWKB2_RS01845 ^@ http://purl.uniprot.org/uniprot/X2H5M3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/1196094:SALWKB2_RS03265 ^@ http://purl.uniprot.org/uniprot/X2HEL9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS03465 ^@ http://purl.uniprot.org/uniprot/X2HER2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1196094:SALWKB2_RS03240 ^@ http://purl.uniprot.org/uniprot/X2HEL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell inner membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/1196094:SALWKB2_RS00920 ^@ http://purl.uniprot.org/uniprot/X2H531 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS06565 ^@ http://purl.uniprot.org/uniprot/X2H8J6 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1196094:SALWKB2_RS05755 ^@ http://purl.uniprot.org/uniprot/X2HBE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS10330 ^@ http://purl.uniprot.org/uniprot/X2HIP7 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/1196094:SALWKB2_RS01555 ^@ http://purl.uniprot.org/uniprot/X2H951 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1196094:SALWKB2_RS09245 ^@ http://purl.uniprot.org/uniprot/X2HI55 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1196094:SALWKB2_RS00985 ^@ http://purl.uniprot.org/uniprot/X2H8U2 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/1196094:SALWKB2_RS06265 ^@ http://purl.uniprot.org/uniprot/X2H5I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/1196094:SALWKB2_RS02760 ^@ http://purl.uniprot.org/uniprot/X2HEB0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS06940 ^@ http://purl.uniprot.org/uniprot/X2H5U0 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1196094:SALWKB2_RS00345 ^@ http://purl.uniprot.org/uniprot/X2H233 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS01345 ^@ http://purl.uniprot.org/uniprot/X2H5F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1196094:SALWKB2_RS10275 ^@ http://purl.uniprot.org/uniprot/X2HE07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05765 ^@ http://purl.uniprot.org/uniprot/X2H7Z4 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1196094:SALWKB2_RS07055 ^@ http://purl.uniprot.org/uniprot/X2H8S0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1196094:SALWKB2_RS01055 ^@ http://purl.uniprot.org/uniprot/X2H568 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1196094:SALWKB2_RS04390 ^@ http://purl.uniprot.org/uniprot/X2H4E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/1196094:SALWKB2_RS11065 ^@ http://purl.uniprot.org/uniprot/X2H862 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1196094:SALWKB2_RS04310 ^@ http://purl.uniprot.org/uniprot/X2HF98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00425 ^@ http://purl.uniprot.org/uniprot/X2H4U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1196094:SALWKB2_RS06835 ^@ http://purl.uniprot.org/uniprot/X2HC14 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/1196094:SALWKB2_RS04275 ^@ http://purl.uniprot.org/uniprot/X2H4C5 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1196094:SALWKB2_RS00305 ^@ http://purl.uniprot.org/uniprot/X2H225 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1196094:SALWKB2_RS10385 ^@ http://purl.uniprot.org/uniprot/X2H7P1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1196094:SALWKB2_RS05620 ^@ http://purl.uniprot.org/uniprot/X2H500 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/1196094:SALWKB2_RS05185 ^@ http://purl.uniprot.org/uniprot/X2HB35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS01255 ^@ http://purl.uniprot.org/uniprot/X2HDL2 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/1196094:SALWKB2_RS07910 ^@ http://purl.uniprot.org/uniprot/X2H6A1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1196094:SALWKB2_RS08150 ^@ http://purl.uniprot.org/uniprot/X2H9C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1196094:SALWKB2_RS09135 ^@ http://purl.uniprot.org/uniprot/X2HDP0 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/1196094:SALWKB2_RS06580 ^@ http://purl.uniprot.org/uniprot/X2HBX9 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1196094:SALWKB2_RS07275 ^@ http://purl.uniprot.org/uniprot/X2HC92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09085 ^@ http://purl.uniprot.org/uniprot/X2HA04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00385 ^@ http://purl.uniprot.org/uniprot/X2H8P7 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1196094:SALWKB2_RS02240 ^@ http://purl.uniprot.org/uniprot/X2H5V7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1196094:SALWKB2_RS01440 ^@ http://purl.uniprot.org/uniprot/X2H939 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/1196094:SALWKB2_RS01185 ^@ http://purl.uniprot.org/uniprot/X2H5A2 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1196094:SALWKB2_RS11155 ^@ http://purl.uniprot.org/uniprot/X2HB72 ^@ Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited. http://togogenome.org/gene/1196094:SALWKB2_RS08195 ^@ http://purl.uniprot.org/uniprot/X2HHG8 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1196094:SALWKB2_RS03105 ^@ http://purl.uniprot.org/uniprot/X2HA67 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS01450 ^@ http://purl.uniprot.org/uniprot/X2H5G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07610 ^@ http://purl.uniprot.org/uniprot/X2HH40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08555 ^@ http://purl.uniprot.org/uniprot/X2H9N8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1196094:SALWKB2_RS11255 ^@ http://purl.uniprot.org/uniprot/X2HBB1 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1196094:SALWKB2_RS09175 ^@ http://purl.uniprot.org/uniprot/X2HA19 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/1196094:SALWKB2_RS02500 ^@ http://purl.uniprot.org/uniprot/X2H9L8 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/1196094:SALWKB2_RS01085 ^@ http://purl.uniprot.org/uniprot/X2H8W8 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1196094:SALWKB2_RS10600 ^@ http://purl.uniprot.org/uniprot/X2HEE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS09980 ^@ http://purl.uniprot.org/uniprot/X2HDU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS05050 ^@ http://purl.uniprot.org/uniprot/X2HBA8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1196094:SALWKB2_RS08590 ^@ http://purl.uniprot.org/uniprot/X2HHT1 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1196094:SALWKB2_RS11415 ^@ http://purl.uniprot.org/uniprot/X2HJJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS05265 ^@ http://purl.uniprot.org/uniprot/X2H4S7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1196094:SALWKB2_RS01605 ^@ http://purl.uniprot.org/uniprot/X2H2V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS00195 ^@ http://purl.uniprot.org/uniprot/X2H8K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS06755 ^@ http://purl.uniprot.org/uniprot/X2HCE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS11695 ^@ http://purl.uniprot.org/uniprot/X2HCJ2 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/1196094:SALWKB2_RS06245 ^@ http://purl.uniprot.org/uniprot/X2HC48 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1196094:SALWKB2_RS05430 ^@ http://purl.uniprot.org/uniprot/X2HB79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS07220 ^@ http://purl.uniprot.org/uniprot/X2HCL3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1196094:SALWKB2_RS05810 ^@ http://purl.uniprot.org/uniprot/X2H545 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10035 ^@ http://purl.uniprot.org/uniprot/X2HE29 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1196094:SALWKB2_RS03010 ^@ http://purl.uniprot.org/uniprot/X2HA44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS04205 ^@ http://purl.uniprot.org/uniprot/X2H4B2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1196094:SALWKB2_RS07340 ^@ http://purl.uniprot.org/uniprot/X2HGY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS08415 ^@ http://purl.uniprot.org/uniprot/X2HHM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1196094:SALWKB2_RS07805 ^@ http://purl.uniprot.org/uniprot/X2HCX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1196094:SALWKB2_RS05720 ^@ http://purl.uniprot.org/uniprot/X2HG09 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/1196094:SALWKB2_RS05445 ^@ http://purl.uniprot.org/uniprot/X2HFU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS09880 ^@ http://purl.uniprot.org/uniprot/X2HAC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1196094:SALWKB2_RS06015 ^@ http://purl.uniprot.org/uniprot/X2HG75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1196094:SALWKB2_RS03365 ^@ http://purl.uniprot.org/uniprot/X2H6I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10160 ^@ http://purl.uniprot.org/uniprot/X2HE47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1196094:SALWKB2_RS10215 ^@ http://purl.uniprot.org/uniprot/X2HDZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P-Pant transferase superfamily. EntD family.|||EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.|||Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively. http://togogenome.org/gene/1196094:SALWKB2_RS02825 ^@ http://purl.uniprot.org/uniprot/X2H3F8 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1196094:SALWKB2_RS03980 ^@ http://purl.uniprot.org/uniprot/X2H475 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1196094:SALWKB2_RS10775 ^@ http://purl.uniprot.org/uniprot/X2HEI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1196094:SALWKB2_RS01815 ^@ http://purl.uniprot.org/uniprot/X2H2Y6 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/1196094:SALWKB2_RS04930 ^@ http://purl.uniprot.org/uniprot/X2HAZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1196094:SALWKB2_RS10675 ^@ http://purl.uniprot.org/uniprot/X2HAU3 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.