http://togogenome.org/gene/1267021:FPB0191_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXA8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1267021:FPB0191_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3K0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1267021:FPB0191_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine. http://togogenome.org/gene/1267021:FPB0191_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A0A7S095 ^@ Caution|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A0A7S528 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4J9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1267021:FPB0191_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8D9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1267021:FPB0191_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S427 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9N1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1267021:FPB0191_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A0A7S523 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1267021:FPB0191_RS11235 ^@ http://purl.uniprot.org/uniprot/L0APE5 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1267021:FPB0191_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2V9 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1267021:FPB0191_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1G9 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1267021:FPB0191_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYE7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1267021:FPB0191_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.|||Belongs to the RseA family.|||Cell inner membrane|||Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB. http://togogenome.org/gene/1267021:FPB0191_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYQ7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS08440 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8C6 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S503 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2P2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1267021:FPB0191_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Y4 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1267021:FPB0191_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6X2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1267021:FPB0191_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A0A7S180 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3X7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZapG family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HemG family.|||Binds 1 FMN non-covalently per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhE family.|||Cytoplasm|||Necessary for formate dehydrogenase activity. http://togogenome.org/gene/1267021:FPB0191_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXH3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A0A7S594 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A0A7S704 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrE/TusD family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2G8 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1267021:FPB0191_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXX5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/1267021:FPB0191_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S234 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Sulfur carrier protein which probably makes part of a sulfur-relay system. http://togogenome.org/gene/1267021:FPB0191_RS09315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2L3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A0A7S139 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0D0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1267021:FPB0191_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A0A7S462 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1267021:FPB0191_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8V7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1267021:FPB0191_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S755 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1267021:FPB0191_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A0A7S113 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1267021:FPB0191_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZP2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1267021:FPB0191_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5X5 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/1267021:FPB0191_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXM9 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1267021:FPB0191_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A0A7S317 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXI8 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1267021:FPB0191_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYN0 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1267021:FPB0191_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1267021:FPB0191_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3D6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1267021:FPB0191_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A0A7S367 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1267021:FPB0191_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1267021:FPB0191_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/1267021:FPB0191_RS09475 ^@ http://purl.uniprot.org/uniprot/L0AQL3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1267021:FPB0191_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1267021:FPB0191_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A0A7S119 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1267021:FPB0191_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYZ7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1267021:FPB0191_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the rusA family.|||Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.|||Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9E1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXY1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS10005 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5B7 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1267021:FPB0191_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Y2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit.|||Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. http://togogenome.org/gene/1267021:FPB0191_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0A7S211 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1267021:FPB0191_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7F9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/1267021:FPB0191_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9M9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1267021:FPB0191_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3G7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1267021:FPB0191_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2T2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3T7 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1267021:FPB0191_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXN5 ^@ Similarity ^@ Belongs to the aldolase LacD family. http://togogenome.org/gene/1267021:FPB0191_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1267021:FPB0191_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A0A7S292 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09040 ^@ http://purl.uniprot.org/uniprot/A0A0A7S473 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A318MS26 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS01230 ^@ http://purl.uniprot.org/uniprot/L0ARM8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXM8 ^@ Function|||Similarity ^@ Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1267021:FPB0191_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6S2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/1267021:FPB0191_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1267021:FPB0191_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A0A7S404 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/1267021:FPB0191_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A0A7S381 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1267021:FPB0191_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S350 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYD2 ^@ Similarity ^@ Belongs to the N-Me-Phe pilin family. http://togogenome.org/gene/1267021:FPB0191_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3H0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/1267021:FPB0191_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A0A7S717 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1267021:FPB0191_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5F7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TrpR family.|||Cytoplasm|||Homodimer.|||This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription. http://togogenome.org/gene/1267021:FPB0191_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A0A7S323 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1267021:FPB0191_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0K2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1267021:FPB0191_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1267021:FPB0191_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A318MS30 ^@ Caution|||Similarity ^@ Belongs to the MlaA family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1267021:FPB0191_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ62 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A0A7S502 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1D2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A0A7S067 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/1267021:FPB0191_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1267021:FPB0191_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXI9 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/1267021:FPB0191_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4J7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/1267021:FPB0191_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Z9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3X2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS00185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A0A7S269 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4C3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1267021:FPB0191_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S677 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1267021:FPB0191_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4P9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1267021:FPB0191_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A0A7S355 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4A0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0G8 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/1267021:FPB0191_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00615 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXM4 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1267021:FPB0191_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A0A7S273 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS11185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Q3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8S4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A0A7S026 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1267021:FPB0191_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ58 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1267021:FPB0191_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3G9 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1267021:FPB0191_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A0A7S931 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/1267021:FPB0191_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0K8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A0A7S424 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1267021:FPB0191_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1267021:FPB0191_RS11110 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3P0 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/1267021:FPB0191_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0A7S952 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1267021:FPB0191_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q2 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/1267021:FPB0191_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4J0 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/1267021:FPB0191_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4G2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1L4 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1267021:FPB0191_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY05 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1267021:FPB0191_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 9 family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A0A7S759 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A0A7S205 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm|||In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/1267021:FPB0191_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A0A7S715 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A0A7S008 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3G3 ^@ Caution|||Function|||Similarity ^@ As this bacterium is not an Enterobacterale, this protein may not have a true dGTPase activity.|||Belongs to the dGTPase family. Type 1 subfamily.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/1267021:FPB0191_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3R4 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1267021:FPB0191_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2B6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1267021:FPB0191_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/1267021:FPB0191_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1267021:FPB0191_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S603 ^@ Similarity ^@ Belongs to the KAE1 / TsaD family. TsaB subfamily. http://togogenome.org/gene/1267021:FPB0191_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3X6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1267021:FPB0191_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Q0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1267021:FPB0191_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZG2 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1267021:FPB0191_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Q1 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ70 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1267021:FPB0191_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5A4 ^@ Similarity ^@ Belongs to the class-C beta-lactamase family. http://togogenome.org/gene/1267021:FPB0191_RS11160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3P9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1267021:FPB0191_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1B0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A0A7S475 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0M6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1267021:FPB0191_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2E1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A0A7S319 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1267021:FPB0191_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZY3 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A0A7S460 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1267021:FPB0191_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0D8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1267021:FPB0191_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ25 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the lipid A palmitoyltransferase family.|||Cell outer membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors. http://togogenome.org/gene/1267021:FPB0191_RS05875 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6Z3 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1267021:FPB0191_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3V5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2F1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. http://togogenome.org/gene/1267021:FPB0191_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY01 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1267021:FPB0191_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Y4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0K0 ^@ Similarity ^@ Belongs to the SIP oxidoreductase family. http://togogenome.org/gene/1267021:FPB0191_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8Q8 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYH4 ^@ Function ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. http://togogenome.org/gene/1267021:FPB0191_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5Q2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1267021:FPB0191_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZY6 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1267021:FPB0191_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A0A7S073 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1267021:FPB0191_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1267021:FPB0191_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1267021:FPB0191_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A0A7S468 ^@ Activity Regulation|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1267021:FPB0191_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0G9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1267021:FPB0191_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5E5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2U1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1267021:FPB0191_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1267021:FPB0191_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0C7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1267021:FPB0191_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1A9 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1267021:FPB0191_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1T0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1267021:FPB0191_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8K3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1267021:FPB0191_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A0A7S750 ^@ Similarity ^@ Belongs to the UPF0339 family. Duplicated subfamily. http://togogenome.org/gene/1267021:FPB0191_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXF1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1267021:FPB0191_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7B3 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1267021:FPB0191_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1267021:FPB0191_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1C9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1267021:FPB0191_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYL9 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A0A7S249 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1267021:FPB0191_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4C7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S632 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MdcC family.|||Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm|||Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. http://togogenome.org/gene/1267021:FPB0191_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A0A7S281 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1267021:FPB0191_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1267021:FPB0191_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXB2 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1267021:FPB0191_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZH4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1267021:FPB0191_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYE8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/1267021:FPB0191_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A0A7S287 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1267021:FPB0191_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI4 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1267021:FPB0191_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Y9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS00785 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1267021:FPB0191_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A0A7S060 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/1267021:FPB0191_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S040 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYX1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2J9 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1267021:FPB0191_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A0A7S325 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/1267021:FPB0191_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S393 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1267021:FPB0191_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A0A7S170 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3J5 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1267021:FPB0191_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZP8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1267021:FPB0191_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A0A7S047 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1F2 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1267021:FPB0191_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5L8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1267021:FPB0191_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1267021:FPB0191_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1267021:FPB0191_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYV7 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1267021:FPB0191_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Q3 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1267021:FPB0191_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1267021:FPB0191_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0A7S887 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ75 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/1267021:FPB0191_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/1267021:FPB0191_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9J4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1267021:FPB0191_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A0A7S835 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1P6 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/1267021:FPB0191_RS11380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1267021:FPB0191_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A0A7S247 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1267021:FPB0191_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A0A7S464 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1267021:FPB0191_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3L9 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1267021:FPB0191_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/1267021:FPB0191_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYC5 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1267021:FPB0191_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYD8 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1267021:FPB0191_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A0A7S252 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1267021:FPB0191_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2F4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1267021:FPB0191_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S898 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYV9 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1267021:FPB0191_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A0A7S001 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0H6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1267021:FPB0191_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5Q6 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Y3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1267021:FPB0191_RS11600 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1267021:FPB0191_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1267021:FPB0191_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1267021:FPB0191_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZL1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1267021:FPB0191_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1L5 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. http://togogenome.org/gene/1267021:FPB0191_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1267021:FPB0191_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A0A7S358 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Binds 1 zinc ion per subunit.|||Divalent metal cations. Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. http://togogenome.org/gene/1267021:FPB0191_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A0A7S136 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A0A7S072 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1267021:FPB0191_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A0A7S890 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1267021:FPB0191_RS11210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1267021:FPB0191_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1267021:FPB0191_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ22 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family. http://togogenome.org/gene/1267021:FPB0191_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9Q7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1267021:FPB0191_RS01490 ^@ http://purl.uniprot.org/uniprot/L0AR87 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1267021:FPB0191_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3W3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1267021:FPB0191_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A0A7S595 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1267021:FPB0191_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A0A7S258 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7M9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1267021:FPB0191_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Q5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1267021:FPB0191_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A0A7S035 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/1267021:FPB0191_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A318MW62 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A0A7S436 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1267021:FPB0191_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZQ8 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1267021:FPB0191_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1267021:FPB0191_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1267021:FPB0191_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXV9 ^@ Similarity ^@ Belongs to the UPF0149 family. http://togogenome.org/gene/1267021:FPB0191_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ78 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1267021:FPB0191_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1W0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1267021:FPB0191_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Part of a sulfur-relay system. http://togogenome.org/gene/1267021:FPB0191_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZY2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W6 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1267021:FPB0191_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1I7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1267021:FPB0191_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A0A7S006 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1267021:FPB0191_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZX1 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1267021:FPB0191_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3T8 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.|||Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ99 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1267021:FPB0191_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1267021:FPB0191_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY46 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1267021:FPB0191_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY83 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S832 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1267021:FPB0191_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/1267021:FPB0191_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A0A7S497 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5V3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/1267021:FPB0191_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0S2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6Q9 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/1267021:FPB0191_RS06875 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. http://togogenome.org/gene/1267021:FPB0191_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A0A7S311 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Y8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1267021:FPB0191_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXB1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZE1 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1267021:FPB0191_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1267021:FPB0191_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S415 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/1267021:FPB0191_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6Y4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1267021:FPB0191_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1267021:FPB0191_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A0A7S202 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1267021:FPB0191_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1267021:FPB0191_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7V8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1267021:FPB0191_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4T7 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY64 ^@ Function|||Miscellaneous|||Similarity ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded. http://togogenome.org/gene/1267021:FPB0191_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2J3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.|||Cytoplasm|||Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). http://togogenome.org/gene/1267021:FPB0191_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2C3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS00745 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXJ0 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. http://togogenome.org/gene/1267021:FPB0191_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYM2 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1267021:FPB0191_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A0A7S184 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1267021:FPB0191_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3T6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1J6 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1267021:FPB0191_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1T9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX88 ^@ Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role. http://togogenome.org/gene/1267021:FPB0191_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXS7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1267021:FPB0191_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0A7S957 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3B3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/1267021:FPB0191_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3H1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A0A7S448 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1267021:FPB0191_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A0A7S129 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1267021:FPB0191_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1267021:FPB0191_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXE5 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1267021:FPB0191_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/1267021:FPB0191_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6D5 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/1267021:FPB0191_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1267021:FPB0191_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS07340 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1A4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0P0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS11015 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3G2 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/1267021:FPB0191_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S511 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1267021:FPB0191_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A0A7S307 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1267021:FPB0191_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ74 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1267021:FPB0191_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1267021:FPB0191_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1267021:FPB0191_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1267021:FPB0191_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZM3 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ67 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1267021:FPB0191_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU3 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1267021:FPB0191_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2S0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1267021:FPB0191_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5C3 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZD7 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/1267021:FPB0191_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY42 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1267021:FPB0191_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1267021:FPB0191_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7Q5 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/1267021:FPB0191_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1267021:FPB0191_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ66 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1267021:FPB0191_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1267021:FPB0191_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1H2 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1267021:FPB0191_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYG9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/1267021:FPB0191_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S821 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/1267021:FPB0191_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A0A7S769 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/1267021:FPB0191_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS00860 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0I1 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/1267021:FPB0191_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4H1 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3K6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1267021:FPB0191_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11165 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3I7 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYI3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1267021:FPB0191_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXY7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1267021:FPB0191_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3I0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1267021:FPB0191_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG9 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1267021:FPB0191_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1M3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1267021:FPB0191_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3B9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1267021:FPB0191_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZB6 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1267021:FPB0191_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8H8 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1267021:FPB0191_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2I8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2M8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Binds two Mg(2+) per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1267021:FPB0191_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A0A7S616 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1267021:FPB0191_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZC8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1267021:FPB0191_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3W6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/1267021:FPB0191_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A0A7S420 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1267021:FPB0191_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7A4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9F0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1267021:FPB0191_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3T9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1267021:FPB0191_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0U0 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1267021:FPB0191_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1A5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1267021:FPB0191_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S500 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS11190 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7M4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1267021:FPB0191_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT3 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1267021:FPB0191_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZD5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZY8 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/1267021:FPB0191_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXV5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYU5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1267021:FPB0191_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7P7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1267021:FPB0191_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A0A7S088 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1267021:FPB0191_RS10315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S363 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/1267021:FPB0191_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1267021:FPB0191_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A0A7S168 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1267021:FPB0191_RS09820 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2S5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXJ5 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1267021:FPB0191_RS11090 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1267021:FPB0191_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1267021:FPB0191_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1267021:FPB0191_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG6 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/1267021:FPB0191_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A0A7S021 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1267021:FPB0191_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0F5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane|||The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB). http://togogenome.org/gene/1267021:FPB0191_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ57 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1267021:FPB0191_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/1267021:FPB0191_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2G4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/1267021:FPB0191_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5N0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5E0 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1267021:FPB0191_RS10000 ^@ http://purl.uniprot.org/uniprot/A0A0A7S914 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXC7 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1267021:FPB0191_RS07300 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4S0 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1267021:FPB0191_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1267021:FPB0191_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1267021:FPB0191_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0R8 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5D5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. http://togogenome.org/gene/1267021:FPB0191_RS05250 ^@ http://purl.uniprot.org/uniprot/L0APN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1267021:FPB0191_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ69 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03040 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0K5 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1267021:FPB0191_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4L9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS03800 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1267021:FPB0191_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN2 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1267021:FPB0191_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S162 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1267021:FPB0191_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A0A7S229 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1267021:FPB0191_RS10155 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4U1 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1267021:FPB0191_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A0A7S875 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A318MT31 ^@ Caution|||Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0L1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9W1 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1267021:FPB0191_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2U7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1267021:FPB0191_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A0A7S926 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1267021:FPB0191_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A0A7S335 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S416 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1267021:FPB0191_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYF5 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1267021:FPB0191_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ55 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1R2 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/1267021:FPB0191_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0J3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2G1 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1267021:FPB0191_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX79 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1267021:FPB0191_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A0A7S480 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1267021:FPB0191_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2K7 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1267021:FPB0191_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U5 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Y8 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1267021:FPB0191_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZD0 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/1267021:FPB0191_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2K8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1267021:FPB0191_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family. RNase II subfamily.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0T2 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1267021:FPB0191_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXR9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1267021:FPB0191_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A0A7S484 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1267021:FPB0191_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8F4 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0R1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/1267021:FPB0191_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ03 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS11530 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9V6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A0A7S839 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1267021:FPB0191_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9C3 ^@ Function|||Similarity ^@ Belongs to the FliK family.|||Controls the length of the flagellar hook. http://togogenome.org/gene/1267021:FPB0191_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ43 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1267021:FPB0191_RS08770 ^@ http://purl.uniprot.org/uniprot/A0A0A7S245 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1267021:FPB0191_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY17 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX76 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXL7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1267021:FPB0191_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0L7 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1267021:FPB0191_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2S8 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/1267021:FPB0191_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A0A7S543 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A0A7S241 ^@ Function|||Similarity ^@ Belongs to the peptidase M16 family.|||Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. http://togogenome.org/gene/1267021:FPB0191_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2P5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1267021:FPB0191_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A0A7S531 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Z5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ33 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1267021:FPB0191_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/1267021:FPB0191_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1E9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/1267021:FPB0191_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS10710 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9I9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1267021:FPB0191_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4E5 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/1267021:FPB0191_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3M6 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1267021:FPB0191_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A0A7S439 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1267021:FPB0191_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A0A7S490 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1267021:FPB0191_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8K0 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1267021:FPB0191_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZE5 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1267021:FPB0191_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1267021:FPB0191_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYI0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY30 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYA4 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/1267021:FPB0191_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7D8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1267021:FPB0191_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1267021:FPB0191_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S195 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1267021:FPB0191_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXG1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW1 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1267021:FPB0191_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A318MU08 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1267021:FPB0191_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS11390 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3U5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S356 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXA0 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1267021:FPB0191_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2K2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1267021:FPB0191_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07110 ^@ http://purl.uniprot.org/uniprot/A0A0A7S330 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1267021:FPB0191_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A0A7S572 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1267021:FPB0191_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3S6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3H6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1267021:FPB0191_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYT0 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1267021:FPB0191_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A0A7S637 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1267021:FPB0191_RS10810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9J9 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1267021:FPB0191_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8M6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1267021:FPB0191_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A0A7S313 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A0A7S394 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1267021:FPB0191_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A0A7S729 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S378 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2W3 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/1267021:FPB0191_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Z9 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1267021:FPB0191_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZL5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS03675 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ23 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/1267021:FPB0191_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5M1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1267021:FPB0191_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1267021:FPB0191_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4D1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1267021:FPB0191_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXV0 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/1267021:FPB0191_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1J5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY19 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1267021:FPB0191_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZN6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1267021:FPB0191_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A0A7S348 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1267021:FPB0191_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1267021:FPB0191_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A0A7S165 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXJ4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1267021:FPB0191_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S763 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A0A7S051 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S188 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1267021:FPB0191_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX74 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class III subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. http://togogenome.org/gene/1267021:FPB0191_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1267021:FPB0191_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXD6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1267021:FPB0191_RS07080 ^@ http://purl.uniprot.org/uniprot/A0A0A7S115 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1267021:FPB0191_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYX6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4U5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1267021:FPB0191_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9J2 ^@ Cofactor|||Function|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. http://togogenome.org/gene/1267021:FPB0191_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A0A7S015 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2V3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1F8 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1267021:FPB0191_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5H7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/1267021:FPB0191_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A0A7S266 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1X0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3E0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7F1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0R3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell inner membrane|||Component of the transport system for branched-chain amino acids.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Syd family.|||Cell inner membrane|||Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. http://togogenome.org/gene/1267021:FPB0191_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4E6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A0A7S421 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2T9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/1267021:FPB0191_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V9 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1267021:FPB0191_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3E3 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/1267021:FPB0191_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX98 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1267021:FPB0191_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A0A7S259 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1267021:FPB0191_RS11525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1K1 ^@ Similarity ^@ Belongs to the protease inhibitor I11 (ecotin) family. http://togogenome.org/gene/1267021:FPB0191_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1E8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1267021:FPB0191_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1C8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXU0 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX69 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1267021:FPB0191_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY06 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1267021:FPB0191_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S175 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZC3 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/1267021:FPB0191_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5D0 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/1267021:FPB0191_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A0A7S905 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ89 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1267021:FPB0191_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1267021:FPB0191_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1267021:FPB0191_RS11370 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1267021:FPB0191_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A0A7S900 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXC9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1267021:FPB0191_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1N0 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/1267021:FPB0191_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1X8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1267021:FPB0191_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A0A7S071 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ04 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1267021:FPB0191_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5E8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1267021:FPB0191_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5C8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1267021:FPB0191_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI7 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/1267021:FPB0191_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6Q3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYE2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1267021:FPB0191_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A0A7S390 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1267021:FPB0191_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1267021:FPB0191_RS06485 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A0A7S320 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1267021:FPB0191_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A0A7S127 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1267021:FPB0191_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/1267021:FPB0191_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1267021:FPB0191_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2B1 ^@ Similarity ^@ Belongs to the phage antitermination Q type 1 family. http://togogenome.org/gene/1267021:FPB0191_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ84 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8P2 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1267021:FPB0191_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A0A7S316 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1267021:FPB0191_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2I5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXH8 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1267021:FPB0191_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4A5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/1267021:FPB0191_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0E8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N8 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1267021:FPB0191_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZH7 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/1267021:FPB0191_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1267021:FPB0191_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S542 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1267021:FPB0191_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5X1 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/1267021:FPB0191_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4N9 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1267021:FPB0191_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3M2 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/1267021:FPB0191_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S366 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1267021:FPB0191_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3A0 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1267021:FPB0191_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A0A7S312 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S395 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/1267021:FPB0191_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1267021:FPB0191_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0P8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1267021:FPB0191_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A318N710 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS11385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5G7 ^@ Cofactor|||Similarity ^@ Belongs to the anthranilate synthase component I family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4L4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/1267021:FPB0191_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1A3 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/1267021:FPB0191_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3T3 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1267021:FPB0191_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2V1 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/1267021:FPB0191_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1267021:FPB0191_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3X1 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1267021:FPB0191_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXQ3 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1267021:FPB0191_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1267021:FPB0191_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZR9 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1267021:FPB0191_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7U0 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1267021:FPB0191_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A0A7S507 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1267021:FPB0191_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5W8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1267021:FPB0191_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A0A7S085 ^@ Similarity ^@ Belongs to the Fmt family. http://togogenome.org/gene/1267021:FPB0191_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5C1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1267021:FPB0191_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4N7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Y9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1267021:FPB0191_RS11075 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9N6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A0A7S741 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homohexamer.|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/1267021:FPB0191_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A0A7S057 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1267021:FPB0191_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4A4 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1267021:FPB0191_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A0A7S120 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/1267021:FPB0191_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5A1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5E1 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1267021:FPB0191_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06765 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0T8 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1267021:FPB0191_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Q6 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1267021:FPB0191_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8T2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS10745 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3I2 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/1267021:FPB0191_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1267021:FPB0191_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1T7 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Methylates ribosomal protein uL3 on a specific glutamine residue. http://togogenome.org/gene/1267021:FPB0191_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2K4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1G3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1267021:FPB0191_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A0A7S432 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1267021:FPB0191_RS02475 ^@ http://purl.uniprot.org/uniprot/L0APQ1 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S795 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/1267021:FPB0191_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZU4 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1267021:FPB0191_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ91 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/1267021:FPB0191_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A0A7S253 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A0A7S328 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1267021:FPB0191_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1N4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1267021:FPB0191_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A0A7S152 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A0A7S555 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1267021:FPB0191_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the porin LamB (TC 1.B.3) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1267021:FPB0191_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S340 ^@ Similarity ^@ In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family. http://togogenome.org/gene/1267021:FPB0191_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1267021:FPB0191_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1267021:FPB0191_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZR2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/1267021:FPB0191_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYB8 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1267021:FPB0191_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1267021:FPB0191_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2R3 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/1267021:FPB0191_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8U8 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1267021:FPB0191_RS11405 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2F6 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1267021:FPB0191_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A318MTA3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1D4 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYI5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1267021:FPB0191_RS11100 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9P1 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/1267021:FPB0191_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXQ1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1267021:FPB0191_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A0A7S334 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1267021:FPB0191_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX86 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1267021:FPB0191_RS09050 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1267021:FPB0191_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2N4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZJ5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1267021:FPB0191_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZJ3 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. KdkA/rfaP family.|||Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. http://togogenome.org/gene/1267021:FPB0191_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1267021:FPB0191_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A318MZL5 ^@ Caution|||Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0A7S044 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1267021:FPB0191_RS07350 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7Q1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/1267021:FPB0191_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY89 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1267021:FPB0191_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZG1 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1267021:FPB0191_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYR8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A0A7S149 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1267021:FPB0191_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A0A7S373 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1267021:FPB0191_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYB6 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/1267021:FPB0191_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZG7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A0A7S036 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1267021:FPB0191_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1267021:FPB0191_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. RsmC family.|||Cytoplasm|||Monomer.|||Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. http://togogenome.org/gene/1267021:FPB0191_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09045 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1267021:FPB0191_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3E6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1267021:FPB0191_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2D5 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1267021:FPB0191_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXS4 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8R1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ65 ^@ Function ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. http://togogenome.org/gene/1267021:FPB0191_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8S8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1267021:FPB0191_RS06865 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0W3 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/1267021:FPB0191_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9R0 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1267021:FPB0191_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Y9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1267021:FPB0191_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1267021:FPB0191_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3F7 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1267021:FPB0191_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A0A7S386 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1267021:FPB0191_RS11535 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5J4 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1267021:FPB0191_RS06850 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZG9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9E6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. METTL16/RlmF family.|||Cytoplasm|||Specifically methylates the adenine in position 1618 of 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A0A7RX51 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/1267021:FPB0191_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6P9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0M3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1267021:FPB0191_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1267021:FPB0191_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5J3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1267021:FPB0191_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A0A7S225 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4I0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1267021:FPB0191_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3R6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1267021:FPB0191_RS06315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A318MQY2 ^@ Caution|||Similarity ^@ Belongs to the bacterial solute-binding protein 3 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S196 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS09105 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2H0 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1267021:FPB0191_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4D7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A0A7S492 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1267021:FPB0191_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ16 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Q1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/1267021:FPB0191_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS11595 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3R8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1267021:FPB0191_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYJ8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A0A7S174 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1267021:FPB0191_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXB7 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1267021:FPB0191_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A0A7S828 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1267021:FPB0191_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYB3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1267021:FPB0191_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A0A7S374 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1267021:FPB0191_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1I6 ^@ Similarity|||Subunit ^@ Belongs to the glutaredoxin family.|||Monomer. http://togogenome.org/gene/1267021:FPB0191_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYA9 ^@ Similarity ^@ Belongs to the DNA polymerase HolA subunit family. http://togogenome.org/gene/1267021:FPB0191_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXN6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1N2 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8M1 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1267021:FPB0191_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1267021:FPB0191_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S488 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1X4 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1267021:FPB0191_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1267021:FPB0191_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0N9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1267021:FPB0191_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A0A7S383 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S517 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/1267021:FPB0191_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5P7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3C2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1267021:FPB0191_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S288 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1267021:FPB0191_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZM5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1267021:FPB0191_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8T4 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1267021:FPB0191_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0S8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1267021:FPB0191_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S364 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1267021:FPB0191_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A0A7S389 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1267021:FPB0191_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A0A7S587 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8A4 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/1267021:FPB0191_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A0A7S645 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1267021:FPB0191_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYR3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1267021:FPB0191_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXF3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1267021:FPB0191_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Z4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1267021:FPB0191_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/1267021:FPB0191_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A0A7S6W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0A7S920 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1267021:FPB0191_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8H3 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZX8 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1267021:FPB0191_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6.|||Represents a citryl-ACP lyase. http://togogenome.org/gene/1267021:FPB0191_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A0A7S372 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1267021:FPB0191_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1267021:FPB0191_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A0A7S308 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A0A7S485 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1267021:FPB0191_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXH4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYN9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1267021:FPB0191_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZV0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1267021:FPB0191_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0E1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYN6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1267021:FPB0191_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A0A7S430 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/1267021:FPB0191_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXN4 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1267021:FPB0191_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0H0 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0F3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1267021:FPB0191_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXV4 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1267021:FPB0191_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYG8 ^@ Similarity ^@ Belongs to the CitG/MdcB family. http://togogenome.org/gene/1267021:FPB0191_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A0A7S003 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3H9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1267021:FPB0191_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ50 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1267021:FPB0191_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A0A7S002 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A318N0M0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS11360 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5G3 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1267021:FPB0191_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1P5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3W5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1267021:FPB0191_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A0A7S961 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1267021:FPB0191_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2U9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1267021:FPB0191_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYB4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/1267021:FPB0191_RS06795 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ96 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/1267021:FPB0191_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9F5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY58 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYC4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1267021:FPB0191_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1C6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2W0 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1267021:FPB0191_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9K6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS10385 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3C9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1267021:FPB0191_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0H2 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1267021:FPB0191_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXB8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5C9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1267021:FPB0191_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A318N6Y5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/1267021:FPB0191_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A0A7S408 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1267021:FPB0191_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9D6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0X1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZA7 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/1267021:FPB0191_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXW4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BexD/CtrA/VexA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZC5 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1267021:FPB0191_RS03060 ^@ http://purl.uniprot.org/uniprot/L0ARL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1267021:FPB0191_RS11305 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MutH family.|||Cytoplasm|||Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. http://togogenome.org/gene/1267021:FPB0191_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1G4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1267021:FPB0191_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3V3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1267021:FPB0191_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1267021:FPB0191_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5J6 ^@ Similarity ^@ Belongs to the UPF0381 family. http://togogenome.org/gene/1267021:FPB0191_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY49 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/1267021:FPB0191_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYA1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/1267021:FPB0191_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A318MVB6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1267021:FPB0191_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A0A7S016 ^@ Function|||Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family.|||CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. http://togogenome.org/gene/1267021:FPB0191_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A0A7S518 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1267021:FPB0191_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7E8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1267021:FPB0191_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SeqA family.|||Cytoplasm|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/1267021:FPB0191_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXY4 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0G0 ^@ Similarity ^@ Belongs to the DDAH family. http://togogenome.org/gene/1267021:FPB0191_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1267021:FPB0191_RS11030 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5A9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1267021:FPB0191_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/1267021:FPB0191_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT5 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1267021:FPB0191_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXM2 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPAT/DAPAT family.|||Cell membrane|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1267021:FPB0191_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1267021:FPB0191_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A0A7S206 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/1267021:FPB0191_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1267021:FPB0191_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1267021:FPB0191_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4H5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/1267021:FPB0191_RS02530 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0I5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A0A7RYR9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/1267021:FPB0191_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1267021:FPB0191_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXQ8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1267021:FPB0191_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/1267021:FPB0191_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1267021:FPB0191_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A0A7S243 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1267021:FPB0191_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S8H0 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A0A7S294 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1267021:FPB0191_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3V8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/1267021:FPB0191_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZW1 ^@ Function|||Similarity ^@ Belongs to the UbiT family.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor. http://togogenome.org/gene/1267021:FPB0191_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS07345 ^@ http://purl.uniprot.org/uniprot/A0A0A7S173 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXY5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A0A7S850 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7S0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5P3 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1267021:FPB0191_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7C9 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/1267021:FPB0191_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A0A7S7K1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2I9 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1267021:FPB0191_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A0A7S193 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1267021:FPB0191_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/1267021:FPB0191_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A0A7S098 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/1267021:FPB0191_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1L2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ19 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/1267021:FPB0191_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A0A7S255 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/1267021:FPB0191_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1267021:FPB0191_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1267021:FPB0191_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1267021:FPB0191_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3V0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A0A7S9G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/1267021:FPB0191_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2V0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1267021:FPB0191_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1J3 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1267021:FPB0191_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1267021:FPB0191_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4Q1 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1267021:FPB0191_RS08975 ^@ http://purl.uniprot.org/uniprot/A0A0A7S284 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A0A7S535 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1267021:FPB0191_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5F4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1267021:FPB0191_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A0A7S177 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5B4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1267021:FPB0191_RS10895 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0L2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1267021:FPB0191_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1Z5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1267021:FPB0191_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A0A7S779 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A0A7S1H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1267021:FPB0191_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A0A7S774 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family. http://togogenome.org/gene/1267021:FPB0191_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A0A7S3Q7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1267021:FPB0191_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A0A7RY03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/1267021:FPB0191_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A0A7S0V6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1267021:FPB0191_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A0A7S132 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1267021:FPB0191_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1267021:FPB0191_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A0A7S145 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A0A7S5Y6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1267021:FPB0191_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXT0 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1267021:FPB0191_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A0A7S189 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/1267021:FPB0191_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1267021:FPB0191_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A0A7RZ60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1267021:FPB0191_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A0A7S2B2 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/1267021:FPB0191_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A0A7S846 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1267021:FPB0191_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1267021:FPB0191_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A0A7RXA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1267021:FPB0191_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A0A7S4R1 ^@ Subcellular Location Annotation ^@ Membrane