http://togogenome.org/gene/1273541:Pyrde_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A0P0MZT9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/1273541:Pyrde_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4V3 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A0P0N446 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1273541:Pyrde_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A0P0N317 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1273541:Pyrde_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDB2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.|||Belongs to the asparaginase 1 family. GatD subfamily.|||Heterodimer of GatD and GatE. http://togogenome.org/gene/1273541:Pyrde_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A0P0N621 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1273541:Pyrde_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A211YQQ5 ^@ Caution|||Similarity ^@ Belongs to the UPF0166 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A211YM93 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2T2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1273541:Pyrde_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A211YN47 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A211YQZ3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A211YLV3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A211YSA1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1X2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS31 family.|||Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A211YQI9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A211YND1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A211YQW2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A211YLT3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2D1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/1273541:Pyrde_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Q5 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1273541:Pyrde_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4B9 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1273541:Pyrde_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2S1 ^@ Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/1273541:Pyrde_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A211YLT0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4U0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1273541:Pyrde_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4G7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1273541:Pyrde_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A0P0N443 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1273541:Pyrde_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A211YQI6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6Q1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M54 family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.|||Monomer.|||Probable zinc metalloprotease whose natural substrate is unknown. http://togogenome.org/gene/1273541:Pyrde_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Q1 ^@ Caution|||Function|||Similarity ^@ Belongs to the Nre family.|||Involved in DNA damage repair.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4F2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TYW1 family.|||Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3X0 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1273541:Pyrde_RS00555 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1Q7 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A211YMJ5 ^@ Caution|||Function|||Similarity ^@ Belongs to the AdoMet synthase 2 family.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1E5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1273541:Pyrde_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5I3 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/1273541:Pyrde_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5W7 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/1273541:Pyrde_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A211YNX3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5U2 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/1273541:Pyrde_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A211YQT2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4C7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1273541:Pyrde_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A211YPX1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5L4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Y2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1273541:Pyrde_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Y9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1273541:Pyrde_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4T6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA. http://togogenome.org/gene/1273541:Pyrde_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0P0N568 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1273541:Pyrde_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0F8 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1273541:Pyrde_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A211YQR8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02445 ^@ http://purl.uniprot.org/uniprot/A0A0P0N246 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS02800 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2T4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1273541:Pyrde_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4M6 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1273541:Pyrde_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A0P0N204 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1273541:Pyrde_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2X0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/1273541:Pyrde_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A211YQ97 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4M2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD58 ^@ Function|||Similarity ^@ Belongs to the TYW3 family.|||S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72. http://togogenome.org/gene/1273541:Pyrde_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5I0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD31 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6J7 ^@ Function|||Similarity ^@ Belongs to the archaeal-type GTP cyclohydrolase family.|||Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity. http://togogenome.org/gene/1273541:Pyrde_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD53 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1273541:Pyrde_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD22 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A211YNV7 ^@ Caution|||Similarity ^@ Belongs to the AOR/FOR family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A211YRQ0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A211YM55 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A0P0N213 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeal MetE family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. http://togogenome.org/gene/1273541:Pyrde_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A0P0N541 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/1273541:Pyrde_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1S6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1273541:Pyrde_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-alpha family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/1273541:Pyrde_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A211YPA9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09235 ^@ http://purl.uniprot.org/uniprot/A0A0P0N548 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1273541:Pyrde_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A0P0N665 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp41 subfamily.|||Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A0P0N414 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1273541:Pyrde_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A211YMH1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A211YLS8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3K5 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1273541:Pyrde_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A211YPS4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3A2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1273541:Pyrde_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A211YNT3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A211YM07 ^@ Caution|||Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01805 ^@ http://purl.uniprot.org/uniprot/A0A211YLR6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A0P0N490 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5U9 ^@ Function|||Similarity ^@ Belongs to the THEP1 NTPase family.|||Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency. http://togogenome.org/gene/1273541:Pyrde_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/1273541:Pyrde_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A0P0N692 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1273541:Pyrde_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A0P0N401 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1273541:Pyrde_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A211YPY4 ^@ Caution|||Subcellular Location Annotation ^@ Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CRISPR system Cmr5 family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A211YNH0 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1273541:Pyrde_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3A9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1273541:Pyrde_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A0P0N281 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSL4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. http://togogenome.org/gene/1273541:Pyrde_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4C8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Part of the 30S ribosomal subunit. Contacts protein S4.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1273541:Pyrde_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A0P0N407 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1273541:Pyrde_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B1 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1273541:Pyrde_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.|||Cell membrane|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/1273541:Pyrde_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0N3 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/1273541:Pyrde_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1N1 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/1273541:Pyrde_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A0P0N211 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A211YP21 ^@ Caution|||Similarity ^@ Belongs to the SAICAR synthetase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N396 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. PoK subfamily.|||Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. http://togogenome.org/gene/1273541:Pyrde_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTH2 family.|||Cytoplasm|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1273541:Pyrde_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4A0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/1273541:Pyrde_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A211YLK5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1273541:Pyrde_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A211YQL7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5I9 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. http://togogenome.org/gene/1273541:Pyrde_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A211YRK0 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the TFE family.|||Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.|||The winged helix domain is involved in binding to DNA in the preinitiation complex.|||Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes. http://togogenome.org/gene/1273541:Pyrde_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3F9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity. http://togogenome.org/gene/1273541:Pyrde_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A211YRA8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A211YPN1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1273541:Pyrde_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1273541:Pyrde_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5G2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1273541:Pyrde_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5F4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1273541:Pyrde_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/1273541:Pyrde_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6A7 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1273541:Pyrde_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Q9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/1273541:Pyrde_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCW9 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eS27 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1273541:Pyrde_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcL subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/1273541:Pyrde_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2X5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6S3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds to the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A0P0N338 ^@ Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family. http://togogenome.org/gene/1273541:Pyrde_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A211YQG1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A211YQ75 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD82 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/1273541:Pyrde_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R6 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1273541:Pyrde_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A211YPT4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD51 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/1273541:Pyrde_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A0P0N499 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6B family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/1273541:Pyrde_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2W6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1273541:Pyrde_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4H3 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/1273541:Pyrde_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A0P0N574 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1273541:Pyrde_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A0P0N368 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1273541:Pyrde_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2D7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A0P0N259 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/1273541:Pyrde_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A211YML1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCT5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. UPF0219 family. http://togogenome.org/gene/1273541:Pyrde_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0P0N557 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1273541:Pyrde_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A0P0N351 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1273541:Pyrde_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1273541:Pyrde_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A0P0N341 ^@ Similarity ^@ In the C-terminal section; belongs to the transposase 35 family. http://togogenome.org/gene/1273541:Pyrde_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A0P0MZW6 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/1273541:Pyrde_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1W8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/1273541:Pyrde_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC61-beta family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3D6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDA0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1273541:Pyrde_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A0P0N671 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1273541:Pyrde_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5G0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1273541:Pyrde_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A0P0N685 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1273541:Pyrde_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A211YN65 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06495 ^@ http://purl.uniprot.org/uniprot/A0A211YLG4 ^@ Caution|||Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A211YQ57 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1273541:Pyrde_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2W2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A0P0N513 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1273541:Pyrde_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5A8 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1273541:Pyrde_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3T8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/1273541:Pyrde_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A211YSD9 ^@ Caution|||Similarity ^@ Belongs to the SIS family. PHI subfamily.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A211YM13 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDF3 ^@ Function ^@ Probably involved in the biogenesis of the ribosome. http://togogenome.org/gene/1273541:Pyrde_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1273541:Pyrde_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD24 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A211YLT4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A0P0N339 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. Probably involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.|||Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA. http://togogenome.org/gene/1273541:Pyrde_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1273541:Pyrde_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A0P0N456 ^@ Similarity ^@ Belongs to the complex I subunit 3 family. http://togogenome.org/gene/1273541:Pyrde_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A211YR22 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1J2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1273541:Pyrde_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A0P0N511 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1273541:Pyrde_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0P0N593 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal DnaG primase family.|||Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. http://togogenome.org/gene/1273541:Pyrde_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A0P0N024 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1273541:Pyrde_RS00180 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1F4 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/1273541:Pyrde_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A211YN48 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3B4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1273541:Pyrde_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A0P0N570 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1273541:Pyrde_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A211YN61 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A211YRX7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A211YQE1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A0P0N470 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1273541:Pyrde_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4K0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.|||Monomer.|||The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity. http://togogenome.org/gene/1273541:Pyrde_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD99 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1273541:Pyrde_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A211YRW3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aTrm56 family.|||Cytoplasm|||Homodimer.|||Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. http://togogenome.org/gene/1273541:Pyrde_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A211YR02 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4E6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1273541:Pyrde_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1273541:Pyrde_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0V6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycerol-1-phosphate dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A0P0N356 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3H9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A211YNV5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4Z2 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.|||In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.|||In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.|||Monomer.|||This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures. http://togogenome.org/gene/1273541:Pyrde_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0X2 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. http://togogenome.org/gene/1273541:Pyrde_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1273541:Pyrde_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0Y9 ^@ Similarity ^@ Belongs to the UPF0273 family. http://togogenome.org/gene/1273541:Pyrde_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1273541:Pyrde_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the beta-RFA-P synthase family.|||Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis). http://togogenome.org/gene/1273541:Pyrde_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A211YRV9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD08 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2G8 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1273541:Pyrde_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2P5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1273541:Pyrde_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Q4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1273541:Pyrde_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCY8 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD15 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/1273541:Pyrde_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A0P0N127 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1273541:Pyrde_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1E1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1273541:Pyrde_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A0P0N677 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/1273541:Pyrde_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. Fibrillarin family.|||Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.|||Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. http://togogenome.org/gene/1273541:Pyrde_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5L9 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs. http://togogenome.org/gene/1273541:Pyrde_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A211YMQ5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A0P0N573 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1273541:Pyrde_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/1273541:Pyrde_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4S0 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1273541:Pyrde_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A0P0N473 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1273541:Pyrde_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0Y3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.|||Homodimer.|||Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. http://togogenome.org/gene/1273541:Pyrde_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A0P0N582 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/1273541:Pyrde_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A211YLJ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A211YPD2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2T7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1273541:Pyrde_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4F0 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1273541:Pyrde_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A0P0N334 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-archaeol synthase family.|||Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/1273541:Pyrde_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5E9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1273541:Pyrde_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A0P0N426 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1273541:Pyrde_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A0P0N399 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/1273541:Pyrde_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6G3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/1273541:Pyrde_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCR2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/1273541:Pyrde_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0V9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/1273541:Pyrde_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4D3 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/1273541:Pyrde_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5M6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.|||Belongs to the Cren7 family.|||Cytoplasm|||Methylated at multiple sites, to varying extents.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0W8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/1273541:Pyrde_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A0P0N262 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1273541:Pyrde_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase small subunit family.|||Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1273541:Pyrde_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3K9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD64 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1273541:Pyrde_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1Y8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.|||Belongs to the TiaS family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A211YNQ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10250 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6I4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS06765 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3U0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. http://togogenome.org/gene/1273541:Pyrde_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A211YNM4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the THI4 family.|||Homooctamer; tetramer of dimers.|||Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A0P0N652 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRP4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. http://togogenome.org/gene/1273541:Pyrde_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.|||Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.|||Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers. http://togogenome.org/gene/1273541:Pyrde_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A211YQS6 ^@ Caution|||Similarity ^@ Belongs to the universal ribosomal protein uS9 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06540 ^@ http://purl.uniprot.org/uniprot/A0A211YLJ5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2S2 ^@ Similarity ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/1273541:Pyrde_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A211YMB4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Q9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1273541:Pyrde_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A211YNU9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1P5 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1273541:Pyrde_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5E7 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3K6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3V5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. http://togogenome.org/gene/1273541:Pyrde_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Q7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3N8 ^@ Function ^@ Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. http://togogenome.org/gene/1273541:Pyrde_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5E2 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/1273541:Pyrde_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A211YS02 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A0P0N189 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. http://togogenome.org/gene/1273541:Pyrde_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A0P0N635 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1273541:Pyrde_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCW5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1273541:Pyrde_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A211YM40 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A211YPB4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3N9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2L9 ^@ Subunit ^@ Heterotetramer of one alpha, one beta, one delta and one gamma chain. http://togogenome.org/gene/1273541:Pyrde_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4Y0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1273541:Pyrde_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A211YRE0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3F2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.|||Belongs to the AAA ATPase family.|||Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.|||Cytoplasm|||Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets. http://togogenome.org/gene/1273541:Pyrde_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1W2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/1273541:Pyrde_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3S2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3V3 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1273541:Pyrde_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A0P0N547 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. http://togogenome.org/gene/1273541:Pyrde_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A211YQM9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A211YLR4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10105 ^@ http://purl.uniprot.org/uniprot/A0A0P0N600 ^@ Similarity ^@ Belongs to the DMRL synthase family. http://togogenome.org/gene/1273541:Pyrde_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4M3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/1273541:Pyrde_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B0 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/1273541:Pyrde_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1M8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1273541:Pyrde_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5U8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL40 family. http://togogenome.org/gene/1273541:Pyrde_RS07185 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B8 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/1273541:Pyrde_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1273541:Pyrde_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCV5 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/1273541:Pyrde_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5T6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1273541:Pyrde_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A0P0N464 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/1273541:Pyrde_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A211YN08 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5L5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal phosphopantothenate synthetase family.|||Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A211YM44 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A0P0N528 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Z0 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1273541:Pyrde_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5B2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1273541:Pyrde_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Z5 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1273541:Pyrde_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A0P0N232 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1273541:Pyrde_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2B0 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1273541:Pyrde_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R4 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1273541:Pyrde_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A0P0N484 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1273541:Pyrde_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A0P0N290 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1273541:Pyrde_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2X1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Y3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1273541:Pyrde_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0P0N397 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/1273541:Pyrde_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A211YQ46 ^@ Caution|||Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2G0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1273541:Pyrde_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A211YR07 ^@ Caution|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2I2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family. http://togogenome.org/gene/1273541:Pyrde_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A0P0N575 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1273541:Pyrde_RS10225 ^@ http://purl.uniprot.org/uniprot/A0A211YQ62 ^@ Caution|||Similarity ^@ Belongs to the universal ribosomal protein uS2 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A211YLJ7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A211YNF1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A211YMM3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3N7 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1273541:Pyrde_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A211YM25 ^@ Caution|||Similarity ^@ Belongs to the SUI1 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4H4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.|||Belongs to the Holliday junction resolvase Hjc family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A211YNJ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09045 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDC8 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1273541:Pyrde_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4J4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A211YQ89 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.|||Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. http://togogenome.org/gene/1273541:Pyrde_RS08920 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A0P0N257 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1273541:Pyrde_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5I2 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1273541:Pyrde_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A0P0N279 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/1273541:Pyrde_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A0P0N138 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1273541:Pyrde_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A211YR48 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08230 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5C2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4D6 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/1273541:Pyrde_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Z0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A0P0N558 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3M7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1273541:Pyrde_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A211YMG2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A0P0N410 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/1273541:Pyrde_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A0P0N244 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1273541:Pyrde_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1273541:Pyrde_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1U6 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/1273541:Pyrde_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A0P0N206 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/1273541:Pyrde_RS08085 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDA4 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/1273541:Pyrde_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1I8 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1273541:Pyrde_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A0P0N299 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the diphthine synthase family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/1273541:Pyrde_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4H8 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/1273541:Pyrde_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NadC/ModD family.|||Hexamer formed by 3 homodimers.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1273541:Pyrde_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A211YQ03 ^@ Caution|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4G4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4R4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A211YLQ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A211YQ78 ^@ Caution|||Similarity ^@ Belongs to the CutA family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A211YM14 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2M9 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1273541:Pyrde_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A211YRJ9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1273541:Pyrde_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4V4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1273541:Pyrde_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5D1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1273541:Pyrde_RS02205 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1273541:Pyrde_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1273541:Pyrde_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1T0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A0P0N447 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2T3 ^@ Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. http://togogenome.org/gene/1273541:Pyrde_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A0P0N468 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1273541:Pyrde_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2G6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/1273541:Pyrde_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A211YQZ0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2L5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCS1 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4L3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the beta-RFA-P synthase family.|||Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).|||Homodimer. http://togogenome.org/gene/1273541:Pyrde_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3V6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1273541:Pyrde_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A0P0N619 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1273541:Pyrde_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1Y3 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.|||In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.|||In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.|||Monomer.|||This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures. http://togogenome.org/gene/1273541:Pyrde_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2M4 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1273541:Pyrde_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1G5 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL20 family.|||Part of the 50S ribosomal subunit. Binds 23S rRNA. http://togogenome.org/gene/1273541:Pyrde_RS08835 ^@ http://purl.uniprot.org/uniprot/A0A211YPL0 ^@ Caution|||Similarity ^@ Belongs to the AOR/FOR family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A211YQE3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A211YQI7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDF8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/1273541:Pyrde_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5I6 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/1273541:Pyrde_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A211YPZ7 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.|||Nucleus|||Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure. http://togogenome.org/gene/1273541:Pyrde_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1U5 ^@ Function ^@ Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA. http://togogenome.org/gene/1273541:Pyrde_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A211YMN1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A211YQL8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A0P0N044 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family. http://togogenome.org/gene/1273541:Pyrde_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6K7 ^@ Function ^@ Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/1273541:Pyrde_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A211YQZ6 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5V5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1273541:Pyrde_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5C7 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2W4 ^@ Similarity ^@ Belongs to the NOP5/NOP56 family. http://togogenome.org/gene/1273541:Pyrde_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A211YMT9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4J1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1273541:Pyrde_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A211YR28 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08360 ^@ http://purl.uniprot.org/uniprot/A0A0P0N515 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1273541:Pyrde_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A0P0N308 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1273541:Pyrde_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1A1 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.|||Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. http://togogenome.org/gene/1273541:Pyrde_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5P9 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1273541:Pyrde_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDE6 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1273541:Pyrde_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A211YMP2 ^@ Caution|||Function|||Similarity ^@ Belongs to the GTP-dependent DPCK family.|||Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/1273541:Pyrde_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A0P0N377 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1273541:Pyrde_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2W7 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1273541:Pyrde_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1W3 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/1273541:Pyrde_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcS subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/1273541:Pyrde_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A211YRZ0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD63 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1273541:Pyrde_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A211YR61 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10735 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A211YMD9 ^@ Caution|||Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A211YS41 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A211YRY9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3H4 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1273541:Pyrde_RS02550 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2J0 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/1273541:Pyrde_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A211YN43 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5S7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/1273541:Pyrde_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1F2 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1273541:Pyrde_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDF7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A0P0N265 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin alpha subunit family.|||Belongs to the prefoldin subunit alpha family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1273541:Pyrde_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD05 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1273541:Pyrde_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3F1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1273541:Pyrde_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Y3 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1273541:Pyrde_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1R4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1273541:Pyrde_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A211YPB9 ^@ Caution|||Similarity ^@ Belongs to the Nth/MutY family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD47 ^@ Similarity ^@ Belongs to the HerA family. http://togogenome.org/gene/1273541:Pyrde_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A211YNM5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3P5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/1273541:Pyrde_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4R5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1273541:Pyrde_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2U3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1273541:Pyrde_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A0N7JCU4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1273541:Pyrde_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4B4 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the SMC family. RAD50 subfamily.|||Binds 1 zinc ion per homodimer.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.|||The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer. http://togogenome.org/gene/1273541:Pyrde_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A0P0N563 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1273541:Pyrde_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0P0N375 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/1273541:Pyrde_RS09780 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1273541:Pyrde_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/1273541:Pyrde_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5M6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.|||Belongs to the Cren7 family.|||Cytoplasm|||Methylated at multiple sites, to varying extents.|||Monomer. http://togogenome.org/gene/1273541:Pyrde_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2N6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0P8 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1273541:Pyrde_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A211YPE8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4P8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1273541:Pyrde_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4U6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1273541:Pyrde_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1273541:Pyrde_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A211YS38 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2H8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A0P0N153 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1273541:Pyrde_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A211YRK1 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A0P0N235 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1273541:Pyrde_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A0P0N476 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3I5 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MRE11/RAD32 family.|||Binds 2 manganese ions per subunit.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Nuclease activity is regulated by Rad50.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. http://togogenome.org/gene/1273541:Pyrde_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1U0 ^@ Similarity ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. http://togogenome.org/gene/1273541:Pyrde_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A211YMA5 ^@ Caution|||Similarity ^@ Belongs to the Ahb/Nir family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3C4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1273541:Pyrde_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A0P0N392 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1273541:Pyrde_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0W0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A211YQT7 ^@ Caution|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1273541:Pyrde_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0P0N455 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. http://togogenome.org/gene/1273541:Pyrde_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1R3 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1273541:Pyrde_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A211YRI0 ^@ Caution|||Subcellular Location Annotation ^@ Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A0P0N380 ^@ Function ^@ The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1273541:Pyrde_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2J1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1273541:Pyrde_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A0P0N606 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1273541:Pyrde_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A0P0N0X3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SPT5 family.|||Belongs to the archaeal Spt5 family.|||Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).|||Stimulates transcription elongation. http://togogenome.org/gene/1273541:Pyrde_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A211YNU2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3J8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/1273541:Pyrde_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A211YRS9 ^@ Caution|||Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A211YRL2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3W4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1273541:Pyrde_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDD4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways. http://togogenome.org/gene/1273541:Pyrde_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4L9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/1273541:Pyrde_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A211YN38 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS07550 ^@ http://purl.uniprot.org/uniprot/A0A0P0N5H3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2F8 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1273541:Pyrde_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A211YNJ4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1273541:Pyrde_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/1273541:Pyrde_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A211YM78 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A211YP59 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A211YN21 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS09760 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6P1 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1273541:Pyrde_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A0P0N284 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1273541:Pyrde_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A0P0N460 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDB0 ^@ Function ^@ Part of a potassium transport system. http://togogenome.org/gene/1273541:Pyrde_RS09730 ^@ http://purl.uniprot.org/uniprot/A0A0N7JDE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1273541:Pyrde_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0N7JD43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/1273541:Pyrde_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A0P0N1E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1273541:Pyrde_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1273541:Pyrde_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A0P0N496 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/1273541:Pyrde_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A0P0N417 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1273541:Pyrde_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0P0N331 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/1273541:Pyrde_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A0P0MZY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAC-alpha family.|||Contacts the emerging nascent chain on the ribosome.|||Homodimer. Interacts with the ribosome. Binds ribosomal RNA. http://togogenome.org/gene/1273541:Pyrde_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A0P0N6D1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL24 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14. http://togogenome.org/gene/1273541:Pyrde_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A0P0N4J3 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1273541:Pyrde_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A211YR20 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/1273541:Pyrde_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A0P0N3Z5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1273541:Pyrde_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A0P0N2K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane