http://togogenome.org/gene/150055:DQN23_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A2X4HV33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/150055:DQN23_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNC0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/150055:DQN23_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A6N3AAV5 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/150055:DQN23_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A2X4F1T0 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/150055:DQN23_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEI2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/150055:DQN23_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBG6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/150055:DQN23_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A6N3AG54 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A2X3WB03 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 73 family. http://togogenome.org/gene/150055:DQN23_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCN3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/150055:DQN23_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A2X4I0I7 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/150055:DQN23_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A2X4F6Z4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/150055:DQN23_RS08810 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJ00 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/150055:DQN23_RS01295 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBA2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A2X4EXN8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/150055:DQN23_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A2X3VSI7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/150055:DQN23_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A2X4F150 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/150055:DQN23_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y3P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBG0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/150055:DQN23_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A2X3VTX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/150055:DQN23_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A6N3AIT8 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/150055:DQN23_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A2X3VRQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A2X4FA92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/150055:DQN23_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A3S5DNG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A6N3D0L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi. http://togogenome.org/gene/150055:DQN23_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A3S5DNJ0 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/150055:DQN23_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A2X3W994 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/150055:DQN23_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A2X4FIC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/150055:DQN23_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGA2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/150055:DQN23_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A2X3W6I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/150055:DQN23_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8Y8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/150055:DQN23_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A2X3WCM8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A2X3VR44 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/150055:DQN23_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A6N2ZMD3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/150055:DQN23_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y800 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y363 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. CshB subfamily.|||Cytoplasm|||Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. http://togogenome.org/gene/150055:DQN23_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A6N3A952 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/150055:DQN23_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A2X4HUJ9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/150055:DQN23_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8U8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/150055:DQN23_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A2X4F0M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/150055:DQN23_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A2X4FIP1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A3S4IPS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/150055:DQN23_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y3X1 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/150055:DQN23_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A2X3VPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A2X4FL12 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/150055:DQN23_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A2X4FF24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/150055:DQN23_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A2X3WC29 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/150055:DQN23_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A2X3VMQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||chloroplast http://togogenome.org/gene/150055:DQN23_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.|||Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A3S4M125 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/150055:DQN23_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A2X4FMT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/150055:DQN23_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A2X3VQF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A2X3W249 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/150055:DQN23_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A6N3DUH2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/150055:DQN23_RS06875 ^@ http://purl.uniprot.org/uniprot/A0A2X3VN95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0298 family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A2X4FED1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/150055:DQN23_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A2X3VSK6 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/150055:DQN23_RS06865 ^@ http://purl.uniprot.org/uniprot/A0A2X3VU16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A2X3VQH0 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/150055:DQN23_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A2X3WE54 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/150055:DQN23_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCI8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/150055:DQN23_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A2X4FDA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/150055:DQN23_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/150055:DQN23_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A2X4FLI2 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAJ5 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/150055:DQN23_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A447UBD8 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/150055:DQN23_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A2X4I054 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A2X4FB67 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/150055:DQN23_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A2X4FEW6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/150055:DQN23_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A2X4F1P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/150055:DQN23_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A2X4F3H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/150055:DQN23_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEK8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/150055:DQN23_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A2X4HSH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y401 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/150055:DQN23_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A2X4FH64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/150055:DQN23_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A3S4KH04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A2X4F132 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/150055:DQN23_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A2X4FEZ6 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/150055:DQN23_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A2X3WDZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A2X4F7R7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS03925 ^@ http://purl.uniprot.org/uniprot/A0A2X4F3Z2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A2X4FE92 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/150055:DQN23_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A447UDQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/150055:DQN23_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A2X3VVT0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/150055:DQN23_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A6N3D5R5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/150055:DQN23_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A2X3W8G4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/150055:DQN23_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A3S4IYX6 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/150055:DQN23_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A2X3W789 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7Q6 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/150055:DQN23_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A2X4FHT9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/150055:DQN23_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A447UDK6 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A6N3BN38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A447UCW2 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/150055:DQN23_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A2X3VKF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/150055:DQN23_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y860 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/150055:DQN23_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/150055:DQN23_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A2X4F521 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A6N3BKB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNH5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/150055:DQN23_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJP8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/150055:DQN23_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A2X3WB75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS01820 ^@ http://purl.uniprot.org/uniprot/A0A2X3VQ88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A447UAQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A447UDM8 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ67 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A6N3DHR9 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A2X3VKA4 ^@ Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A2X4F398 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A2X4HV67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/150055:DQN23_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A2X3WF89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/150055:DQN23_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A2X4FGK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the YabA family.|||Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.|||Involved in initiation control of chromosome replication. http://togogenome.org/gene/150055:DQN23_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A6N3DUJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/150055:DQN23_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y442 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/150055:DQN23_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A2X4FB87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/150055:DQN23_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZ59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/150055:DQN23_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A3S4HZU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/150055:DQN23_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A3S4LZL3 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/150055:DQN23_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A2X4F327 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/150055:DQN23_RS09010 ^@ http://purl.uniprot.org/uniprot/A0A2X3VPI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y6Q9 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/150055:DQN23_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A2X3W9V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/150055:DQN23_RS08920 ^@ http://purl.uniprot.org/uniprot/A0A2X3WCL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A2X4EYZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/150055:DQN23_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGD2 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/150055:DQN23_RS08960 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZS2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/150055:DQN23_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJ26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBZ8 ^@ Similarity|||Subunit ^@ Belongs to the LacAB/RpiB family.|||Heteromultimeric protein consisting of LacA and LacB. http://togogenome.org/gene/150055:DQN23_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A2X4EYG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. DivIB subfamily.|||Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.|||Cell membrane http://togogenome.org/gene/150055:DQN23_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y8K0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/150055:DQN23_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A447UF86 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A3S4JKX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A2X4FDW8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/150055:DQN23_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A447UE34 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/150055:DQN23_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A2X4FK44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/150055:DQN23_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBW1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/150055:DQN23_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/150055:DQN23_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A2X3VPQ2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/150055:DQN23_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A2X3WA32 ^@ Similarity ^@ Belongs to the UPF0223 family. http://togogenome.org/gene/150055:DQN23_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A2X3VK82 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/150055:DQN23_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A2X3WF02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/150055:DQN23_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNS9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/150055:DQN23_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFH0 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/150055:DQN23_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A2X4FFJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A2X4EZM9 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/150055:DQN23_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A2X4EZU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A2X4FFI6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/150055:DQN23_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS08455 ^@ http://purl.uniprot.org/uniprot/A0A6N2YCF3 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/150055:DQN23_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A2X3WB90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A2X3WE36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8Y6 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/150055:DQN23_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A2X4FH21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/150055:DQN23_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A2X4FHV7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A2X3VP43 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/150055:DQN23_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A6N3CLC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A2X4FGW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/150055:DQN23_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A2X4F6K4 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/150055:DQN23_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A2X4FMB4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/150055:DQN23_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A2X4HUL5 ^@ Similarity ^@ Belongs to the UPF0374 family. http://togogenome.org/gene/150055:DQN23_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A2X3VQ11 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/150055:DQN23_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A2X3VYG9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/150055:DQN23_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A2X4I201 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/150055:DQN23_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A2X3W799 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A2X4F181 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/150055:DQN23_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/150055:DQN23_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A2X4F5B7 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/150055:DQN23_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A3S4IPG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A447UBT6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A2X3VWY4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/150055:DQN23_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/150055:DQN23_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A6N3D0V0 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/150055:DQN23_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJ14 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/150055:DQN23_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A447UF05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/150055:DQN23_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A2X3VN40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/150055:DQN23_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A2X4F612 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/150055:DQN23_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFV7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/150055:DQN23_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A3S4I564 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/150055:DQN23_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ34 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A2X4F5H5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/150055:DQN23_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A447UEX5 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/150055:DQN23_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A2X4EXB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/150055:DQN23_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBA6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/150055:DQN23_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A6N3CXS7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/150055:DQN23_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A2X4F2U4 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/150055:DQN23_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A6N2Z5L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/150055:DQN23_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A2X3WAX8 ^@ Function ^@ Required for transformation and DNA binding. http://togogenome.org/gene/150055:DQN23_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y4H1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/150055:DQN23_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/150055:DQN23_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A6N3AJ49 ^@ Similarity ^@ Belongs to the UPF0346 family. http://togogenome.org/gene/150055:DQN23_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A2X4FHP5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/150055:DQN23_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJA8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/150055:DQN23_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A6N2Z7F8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/150055:DQN23_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A447UE52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A2X3W8U3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/150055:DQN23_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCE7 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/150055:DQN23_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.|||Cell membrane|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. http://togogenome.org/gene/150055:DQN23_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGI5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/150055:DQN23_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A2X4EV00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEV9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/150055:DQN23_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A2X4FEC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/150055:DQN23_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A3S4IY64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A6N2ZPA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A6N3A818 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/150055:DQN23_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A3S4M1U0 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/150055:DQN23_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A2X3VPI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/150055:DQN23_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A2X3VT62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/150055:DQN23_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A6N3DSL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S15 family.|||Cytoplasm|||Homodimer.|||Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. http://togogenome.org/gene/150055:DQN23_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7J9 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/150055:DQN23_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A2X3W2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y3G4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/150055:DQN23_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A447UB15 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family. DapH subfamily.|||Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. http://togogenome.org/gene/150055:DQN23_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/150055:DQN23_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A2X4F917 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/150055:DQN23_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A447UDN0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 73 family. http://togogenome.org/gene/150055:DQN23_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A2X4FKL9 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/150055:DQN23_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A6N2YWT1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/150055:DQN23_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A2X3VP81 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y5J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A2X3VN30 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. http://togogenome.org/gene/150055:DQN23_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A2X4F121 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/150055:DQN23_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A2X4F3J4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A2X3WG09 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/150055:DQN23_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/150055:DQN23_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A2X4FB96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/150055:DQN23_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A2X4HXR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/150055:DQN23_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A447UAD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/150055:DQN23_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A2X4FD44 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/150055:DQN23_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A2X4FGC7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A2X4F6U4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A2X4F493 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A2X4F601 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/150055:DQN23_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/150055:DQN23_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A2X4HVK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/150055:DQN23_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A2X4F7T2 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/150055:DQN23_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A6N3ED71 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A2X3VTY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/150055:DQN23_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A2X4F7I9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/150055:DQN23_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A2X4FA13 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/150055:DQN23_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFK5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/150055:DQN23_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A6N3C859 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/150055:DQN23_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A447UCE9 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/150055:DQN23_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A6N3C1B0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 73 family. http://togogenome.org/gene/150055:DQN23_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y3T7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/150055:DQN23_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFE8 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/150055:DQN23_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/150055:DQN23_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A2X3W6S2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/150055:DQN23_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y719 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A2X4F899 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/150055:DQN23_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGM8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/150055:DQN23_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A2X4HZM0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A2X4FEB7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/150055:DQN23_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A2X4FMC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/150055:DQN23_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A2X3VSJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArsC family. Spx subfamily.|||Cytoplasm|||Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.|||Interacts with the C-terminal domain of the alpha subunit of the RNAP. http://togogenome.org/gene/150055:DQN23_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A6N3C8F4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/150055:DQN23_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A2X4F2A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A2X3W8X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0154 family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A2X4HYN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/150055:DQN23_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A2X4HV49 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/150055:DQN23_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A2X4EXH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS02875 ^@ http://purl.uniprot.org/uniprot/A0A2X4F7U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. CshA subfamily.|||Cytoplasm|||DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.|||Oligomerizes, may be a member of the RNA degradosome. http://togogenome.org/gene/150055:DQN23_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A6N3CXU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/150055:DQN23_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A2X3VVX1 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/150055:DQN23_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBW7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/150055:DQN23_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A447UC54 ^@ Similarity ^@ Belongs to the thioester dehydratase family. FabZ subfamily. http://togogenome.org/gene/150055:DQN23_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZT3 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/150055:DQN23_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A2X4FA07 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A2X4EWU0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/150055:DQN23_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A2X3VN01 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/150055:DQN23_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A2X4FDU1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. http://togogenome.org/gene/150055:DQN23_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A2X4HTM7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/150055:DQN23_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A3S4JJ82 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/150055:DQN23_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A3S4HZR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A2X3W3P8 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/150055:DQN23_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A447UCW3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/150055:DQN23_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A2X4EUU6 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/150055:DQN23_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A3S4JLR5 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/150055:DQN23_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A6N3AES1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/150055:DQN23_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A6N3A2Z9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8X1 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/150055:DQN23_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A2X3W851 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/150055:DQN23_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A2X4F4C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRP transporter (TC 2.A.7.5) family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7X2 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/150055:DQN23_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A447UAU6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/150055:DQN23_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAI6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/150055:DQN23_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A2X3W8I9 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/150055:DQN23_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A2X4EWM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/150055:DQN23_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A447UDJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBQ3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/150055:DQN23_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A2X3W863 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/150055:DQN23_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A6N2YLD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/150055:DQN23_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJB0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A6N2Z521 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/150055:DQN23_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A3S4I1V9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/150055:DQN23_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A2X4HVJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/150055:DQN23_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A2X3WF80 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/150055:DQN23_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A2X4HWI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A2X3VXE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y848 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/150055:DQN23_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A2X3VQJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/150055:DQN23_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A2X4HXP9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/150055:DQN23_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A2X3VNU8 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/150055:DQN23_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A2X4FIW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFN1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A2X3VL59 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/150055:DQN23_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A6N3CLA8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A2X4I0T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/150055:DQN23_RS01285 ^@ http://purl.uniprot.org/uniprot/A0A3S4IP50 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/150055:DQN23_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A2X4EZ02 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/150055:DQN23_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/150055:DQN23_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A6N3A210 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A2X4FI33 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/150055:DQN23_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7L4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/150055:DQN23_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJ89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HPr family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.|||P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity. http://togogenome.org/gene/150055:DQN23_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A2X3WGN7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/150055:DQN23_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A3S4M442 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/150055:DQN23_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A3S4IY40 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/150055:DQN23_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A447UD61 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/150055:DQN23_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A2X3WFW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/150055:DQN23_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A447UCW7 ^@ Subcellular Location Annotation ^@ Cell surface http://togogenome.org/gene/150055:DQN23_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A2X3VTJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A2X3VME0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/150055:DQN23_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A2X4F1S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A2X3WB34 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/150055:DQN23_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y2Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/150055:DQN23_RS08495 ^@ http://purl.uniprot.org/uniprot/A0A2X4F4X5 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/150055:DQN23_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A447UEY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/150055:DQN23_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A447UEV6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A2X4F4L1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/150055:DQN23_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A2X4FNI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A2X3W8P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBT6 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/150055:DQN23_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A447UC63 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/150055:DQN23_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/150055:DQN23_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A2X3VMC5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/150055:DQN23_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ86 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/150055:DQN23_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBE0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/150055:DQN23_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A2X4HYV3 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/150055:DQN23_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A2X4F4Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/150055:DQN23_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A2X4FN08 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/150055:DQN23_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y4R5 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/150055:DQN23_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A447UDM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A2X3VZR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/150055:DQN23_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7W0 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/150055:DQN23_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A2X4FES6 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/150055:DQN23_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y4S8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/150055:DQN23_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEJ2 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/150055:DQN23_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A2X4F4D9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/150055:DQN23_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y2A7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/150055:DQN23_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJL2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/150055:DQN23_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A3S4M1A6 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/150055:DQN23_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A2X4FHV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein bS18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A2X3WBS9 ^@ Function|||Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH. http://togogenome.org/gene/150055:DQN23_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A2X4HT24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A3S4IAG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/150055:DQN23_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7N9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/150055:DQN23_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A2X3WG68 ^@ Function|||Similarity|||Subunit ^@ A non-essential component of RNA polymerase (RNAP).|||Belongs to the RNA polymerase subunit epsilon family.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/150055:DQN23_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A3S4I1S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/150055:DQN23_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A2X4F7U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A3S4IZW2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/150055:DQN23_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y7R7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/150055:DQN23_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A2X3WB14 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/150055:DQN23_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A2X3VMX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/150055:DQN23_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. http://togogenome.org/gene/150055:DQN23_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A2X4FBH8 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/150055:DQN23_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A2X4FAB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/150055:DQN23_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A2X3VM62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A2X4F6I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/150055:DQN23_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A2X3WC18 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/150055:DQN23_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A2X3VK75 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/150055:DQN23_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A2X4F8R1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/150055:DQN23_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/150055:DQN23_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A2X4FCK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/150055:DQN23_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A447UE28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EzrA family.|||Cell membrane|||Membrane|||Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization. http://togogenome.org/gene/150055:DQN23_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A6N3DG39 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/150055:DQN23_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7Y3 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/150055:DQN23_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A2X4HU01 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/150055:DQN23_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A2X3VUT1 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/150055:DQN23_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJK5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/150055:DQN23_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A447UA08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A2X4FDA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A6N3B6I7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/150055:DQN23_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJQ0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A2X3W7Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/150055:DQN23_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y767 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/150055:DQN23_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A3S4I1B6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/150055:DQN23_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A447UAU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/150055:DQN23_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A2X3Y741 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/150055:DQN23_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A2X3VYA9 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/150055:DQN23_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A3S4I2S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/150055:DQN23_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A6N3E1C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/150055:DQN23_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A2X3VMV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/150055:DQN23_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A2X4FC37 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/150055:DQN23_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A2X3VN03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A2X4I0J1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/150055:DQN23_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A2X3VJ57 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/150055:DQN23_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A3S4M3W1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/150055:DQN23_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A2X3WEP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A6N2ZQ25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/150055:DQN23_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A2X3VT40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/150055:DQN23_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A2X4FEE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A2X4I1G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/150055:DQN23_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A6N2YHT4 ^@ Similarity ^@ Belongs to the LOR family. http://togogenome.org/gene/150055:DQN23_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A2X4FJJ3 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/150055:DQN23_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A2X4F171 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/150055:DQN23_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A2X3W318 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.