http://togogenome.org/gene/194439:AYT24_RS09400 ^@ http://purl.uniprot.org/uniprot/Q8KAS2 ^@ Similarity ^@ Belongs to the CIA30 family. http://togogenome.org/gene/194439:AYT24_RS05700 ^@ http://purl.uniprot.org/uniprot/Q8KCZ6 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/194439:AYT24_RS01725 ^@ http://purl.uniprot.org/uniprot/Q8KFH6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/194439:AYT24_RS00405 ^@ http://purl.uniprot.org/uniprot/Q8KG86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF nuclease family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS04655 ^@ http://purl.uniprot.org/uniprot/Q8KDN4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/194439:AYT24_RS01190 ^@ http://purl.uniprot.org/uniprot/Q8KFT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/194439:AYT24_RS00545 ^@ http://purl.uniprot.org/uniprot/Q8KG56 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/194439:AYT24_RS08080 ^@ http://purl.uniprot.org/uniprot/Q8KBJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/194439:AYT24_RS06365 ^@ http://purl.uniprot.org/uniprot/Q8KCK7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS10575 ^@ http://purl.uniprot.org/uniprot/Q8KBA9 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/194439:AYT24_RS10225 ^@ http://purl.uniprot.org/uniprot/Q8KAB0 ^@ Similarity ^@ Belongs to the geranylgeranyl reductase family. ChlP subfamily. http://togogenome.org/gene/194439:AYT24_RS02850 ^@ http://purl.uniprot.org/uniprot/Q8KES3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the final reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.|||Cytoplasm|||Homodimer.|||Slightly inhibited by N-acetyldopamine but not by N-acetylserotonin or melatonin. http://togogenome.org/gene/194439:AYT24_RS09590 ^@ http://purl.uniprot.org/uniprot/Q8KAN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/194439:AYT24_RS10035 ^@ http://purl.uniprot.org/uniprot/Q8KAE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/194439:AYT24_RS08645 ^@ http://purl.uniprot.org/uniprot/Q8KB76 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/194439:AYT24_RS00605 ^@ http://purl.uniprot.org/uniprot/Q8KG42 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/194439:AYT24_RS00030 ^@ http://purl.uniprot.org/uniprot/Q8KGG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/194439:AYT24_RS03855 ^@ http://purl.uniprot.org/uniprot/Q8KE66 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/194439:AYT24_RS03370 ^@ http://purl.uniprot.org/uniprot/Q8KEG7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/194439:AYT24_RS02335 ^@ http://purl.uniprot.org/uniprot/Q8KF48 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS08055 ^@ http://purl.uniprot.org/uniprot/Q8KBK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/194439:AYT24_RS06325 ^@ http://purl.uniprot.org/uniprot/Q8KCL7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS00110 ^@ http://purl.uniprot.org/uniprot/Q8KGE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/194439:AYT24_RS00495 ^@ http://purl.uniprot.org/uniprot/Q8KG66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS08125 ^@ http://purl.uniprot.org/uniprot/Q8KBI9 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/194439:AYT24_RS09625 ^@ http://purl.uniprot.org/uniprot/Q8KAM6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/194439:AYT24_RS05205 ^@ http://purl.uniprot.org/uniprot/Q8KDA3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/194439:AYT24_RS01385 ^@ http://purl.uniprot.org/uniprot/Q8KFP3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/194439:AYT24_RS08405 ^@ http://purl.uniprot.org/uniprot/Q8KBD1 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/194439:AYT24_RS08165 ^@ http://purl.uniprot.org/uniprot/Q8KBI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/194439:AYT24_RS09065 ^@ http://purl.uniprot.org/uniprot/Q8KAZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/194439:AYT24_RS05815 ^@ http://purl.uniprot.org/uniprot/Q8KCX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/194439:AYT24_RS04540 ^@ http://purl.uniprot.org/uniprot/Q8KDR0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/194439:AYT24_RS08035 ^@ http://purl.uniprot.org/uniprot/P59003 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/194439:AYT24_RS00585 ^@ http://purl.uniprot.org/uniprot/Q8KG45 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/194439:AYT24_RS07200 ^@ http://purl.uniprot.org/uniprot/Q8KC34 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/194439:AYT24_RS01500 ^@ http://purl.uniprot.org/uniprot/Q9F721 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome b family.|||Binds 2 heme b groups non-covalently.|||Cell inner membrane|||Component of the green S-bacteria bc complex, which consists of the Rieske protein and cytochrome b subunit but appears to lack a cytochrome c1-equivalent. This complex has a comparatively low redox potential (By similarity).|||Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm. http://togogenome.org/gene/194439:AYT24_RS09680 ^@ http://purl.uniprot.org/uniprot/Q8KAL5 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/194439:AYT24_RS08905 ^@ http://purl.uniprot.org/uniprot/Q8KB28 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/194439:AYT24_RS07590 ^@ http://purl.uniprot.org/uniprot/Q8KBV0 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/194439:AYT24_RS01270 ^@ http://purl.uniprot.org/uniprot/Q8KFR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/194439:AYT24_RS07435 ^@ http://purl.uniprot.org/uniprot/Q8KBY5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/194439:AYT24_RS08760 ^@ http://purl.uniprot.org/uniprot/Q8KB54 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/194439:AYT24_RS00335 ^@ http://purl.uniprot.org/uniprot/Q8KGA2 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/194439:AYT24_RS03200 ^@ http://purl.uniprot.org/uniprot/Q8KEK1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/194439:AYT24_RS03495 ^@ http://purl.uniprot.org/uniprot/Q8KEE2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/194439:AYT24_RS00435 ^@ http://purl.uniprot.org/uniprot/Q8KG80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS00680 ^@ http://purl.uniprot.org/uniprot/P59040 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/194439:AYT24_RS02840 ^@ http://purl.uniprot.org/uniprot/Q8KES6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/194439:AYT24_RS06380 ^@ http://purl.uniprot.org/uniprot/Q8KCK4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/194439:AYT24_RS03635 ^@ http://purl.uniprot.org/uniprot/Q8KEB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06120 ^@ http://purl.uniprot.org/uniprot/Q8KCR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS00660 ^@ http://purl.uniprot.org/uniprot/Q8KG30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS02310 ^@ http://purl.uniprot.org/uniprot/Q8KF53 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/194439:AYT24_RS09220 ^@ http://purl.uniprot.org/uniprot/Q8KAW0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/194439:AYT24_RS02280 ^@ http://purl.uniprot.org/uniprot/Q8KF60 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/194439:AYT24_RS03260 ^@ http://purl.uniprot.org/uniprot/Q8KEI8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/194439:AYT24_RS05615 ^@ http://purl.uniprot.org/uniprot/Q8KD16 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS08030 ^@ http://purl.uniprot.org/uniprot/Q8KBK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/194439:AYT24_RS09620 ^@ http://purl.uniprot.org/uniprot/Q8KAM7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/194439:AYT24_RS09845 ^@ http://purl.uniprot.org/uniprot/Q8KAI8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/194439:AYT24_RS04745 ^@ http://purl.uniprot.org/uniprot/Q8KDL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/194439:AYT24_RS00265 ^@ http://purl.uniprot.org/uniprot/Q8KGB5 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/194439:AYT24_RS07535 ^@ http://purl.uniprot.org/uniprot/Q8KBW1 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/194439:AYT24_RS09515 ^@ http://purl.uniprot.org/uniprot/Q8KAP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS03365 ^@ http://purl.uniprot.org/uniprot/Q8KEG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/194439:AYT24_RS00480 ^@ http://purl.uniprot.org/uniprot/Q8KG70 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/194439:AYT24_RS01450 ^@ http://purl.uniprot.org/uniprot/Q8KFM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS01800 ^@ http://purl.uniprot.org/uniprot/Q8KFF8 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS03670 ^@ http://purl.uniprot.org/uniprot/Q8KEA4 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family.|||Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. http://togogenome.org/gene/194439:AYT24_RS06655 ^@ http://purl.uniprot.org/uniprot/Q8KCE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01675 ^@ http://purl.uniprot.org/uniprot/Q8KFI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS03590 ^@ http://purl.uniprot.org/uniprot/Q8KEC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS06125 ^@ http://purl.uniprot.org/uniprot/Q8KCR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS06455 ^@ http://purl.uniprot.org/uniprot/Q93ST4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/194439:AYT24_RS05555 ^@ http://purl.uniprot.org/uniprot/Q8KD27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS00860 ^@ http://purl.uniprot.org/uniprot/Q8KFZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS05110 ^@ http://purl.uniprot.org/uniprot/Q8KDC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/194439:AYT24_RS06570 ^@ http://purl.uniprot.org/uniprot/Q8KCH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/194439:AYT24_RS00080 ^@ http://purl.uniprot.org/uniprot/Q8KGF2 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/194439:AYT24_RS07055 ^@ http://purl.uniprot.org/uniprot/Q8KC66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS03625 ^@ http://purl.uniprot.org/uniprot/Q8KEB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS07690 ^@ http://purl.uniprot.org/uniprot/Q8KBS6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible SMC hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/194439:AYT24_RS01815 ^@ http://purl.uniprot.org/uniprot/Q8KFF5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS01890 ^@ http://purl.uniprot.org/uniprot/Q8KFD9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/194439:AYT24_RS08395 ^@ http://purl.uniprot.org/uniprot/Q8KBD3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS06810 ^@ http://purl.uniprot.org/uniprot/Q8KCB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/194439:AYT24_RS06025 ^@ http://purl.uniprot.org/uniprot/P59014 ^@ Function|||Similarity ^@ Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||In the C-terminal section; belongs to the MoaB/Mog family.|||In the N-terminal section; belongs to the MoaC family. http://togogenome.org/gene/194439:AYT24_RS09885 ^@ http://purl.uniprot.org/uniprot/Q8KAI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/194439:AYT24_RS09550 ^@ http://purl.uniprot.org/uniprot/Q8KAP1 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/194439:AYT24_RS07240 ^@ http://purl.uniprot.org/uniprot/Q8KC24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01295 ^@ http://purl.uniprot.org/uniprot/Q8KFR0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/194439:AYT24_RS02965 ^@ http://purl.uniprot.org/uniprot/Q8KEQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06095 ^@ http://purl.uniprot.org/uniprot/Q8KCR8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS08680 ^@ http://purl.uniprot.org/uniprot/Q8KB68 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/194439:AYT24_RS02020 ^@ http://purl.uniprot.org/uniprot/Q8KFA9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunit H family. http://togogenome.org/gene/194439:AYT24_RS05485 ^@ http://purl.uniprot.org/uniprot/Q8KD46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01520 ^@ http://purl.uniprot.org/uniprot/Q8KFL9 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/194439:AYT24_RS00325 ^@ http://purl.uniprot.org/uniprot/Q8KGA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/194439:AYT24_RS08720 ^@ http://purl.uniprot.org/uniprot/Q8KB62 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS00780 ^@ http://purl.uniprot.org/uniprot/Q8KG16 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/194439:AYT24_RS02550 ^@ http://purl.uniprot.org/uniprot/Q8KEY9 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/194439:AYT24_RS01430 ^@ http://purl.uniprot.org/uniprot/Q8KFN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS03885 ^@ http://purl.uniprot.org/uniprot/Q8KE60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS00400 ^@ http://purl.uniprot.org/uniprot/Q8KG87 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/194439:AYT24_RS08820 ^@ http://purl.uniprot.org/uniprot/Q8KB41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS02180 ^@ http://purl.uniprot.org/uniprot/Q8KF79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/194439:AYT24_RS00005 ^@ http://purl.uniprot.org/uniprot/Q8KGG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/194439:AYT24_RS00760 ^@ http://purl.uniprot.org/uniprot/Q8KG20 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/194439:AYT24_RS06075 ^@ http://purl.uniprot.org/uniprot/Q8KCS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS09820 ^@ http://purl.uniprot.org/uniprot/Q8KAJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/194439:AYT24_RS04820 ^@ http://purl.uniprot.org/uniprot/Q8KDK0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/194439:AYT24_RS03045 ^@ http://purl.uniprot.org/uniprot/Q8KEN5 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/194439:AYT24_RS03950 ^@ http://purl.uniprot.org/uniprot/Q8KE43 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/194439:AYT24_RS05465 ^@ http://purl.uniprot.org/uniprot/Q8KD49 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/194439:AYT24_RS08860 ^@ http://purl.uniprot.org/uniprot/Q8KB36 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/194439:AYT24_RS01985 ^@ http://purl.uniprot.org/uniprot/Q8KFB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06480 ^@ http://purl.uniprot.org/uniprot/Q8KCJ0 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).|||Does not seem to have a metal requirement for activity.|||Homooctamer.|||Stimulated by magnesium, inhibited by zinc. http://togogenome.org/gene/194439:AYT24_RS06690 ^@ http://purl.uniprot.org/uniprot/Q8KCE2 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS09040 ^@ http://purl.uniprot.org/uniprot/Q8KAZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/194439:AYT24_RS01340 ^@ http://purl.uniprot.org/uniprot/Q8KFQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/194439:AYT24_RS07220 ^@ http://purl.uniprot.org/uniprot/Q8KC30 ^@ Similarity ^@ Belongs to the glycogen phosphorylase family. http://togogenome.org/gene/194439:AYT24_RS08795 ^@ http://purl.uniprot.org/uniprot/Q8KB48 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/194439:AYT24_RS06855 ^@ http://purl.uniprot.org/uniprot/Q8KCB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/194439:AYT24_RS05820 ^@ http://purl.uniprot.org/uniprot/Q8KCX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS07175 ^@ http://purl.uniprot.org/uniprot/Q8KC40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00465 ^@ http://purl.uniprot.org/uniprot/Q8KG74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09385 ^@ http://purl.uniprot.org/uniprot/Q8KAS5 ^@ Function|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 1 heme c group covalently per subunit.|||Dimer of one cytochrome and one flavoprotein.|||Monoheme cytochrome that function as the electron transport subunit of sulfide dehydrogenase.|||Periplasm http://togogenome.org/gene/194439:AYT24_RS02820 ^@ http://purl.uniprot.org/uniprot/Q8KET0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/194439:AYT24_RS06565 ^@ http://purl.uniprot.org/uniprot/Q8KCH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS07855 ^@ http://purl.uniprot.org/uniprot/Q8KBP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/194439:AYT24_RS00815 ^@ http://purl.uniprot.org/uniprot/Q8KG09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09810 ^@ http://purl.uniprot.org/uniprot/Q8KAJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/194439:AYT24_RS01335 ^@ http://purl.uniprot.org/uniprot/Q8KFQ4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/194439:AYT24_RS06720 ^@ http://purl.uniprot.org/uniprot/Q8KCD5 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/194439:AYT24_RS07000 ^@ http://purl.uniprot.org/uniprot/Q8KC76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09905 ^@ http://purl.uniprot.org/uniprot/Q8KAH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/194439:AYT24_RS07030 ^@ http://purl.uniprot.org/uniprot/Q8KC71 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS00215 ^@ http://purl.uniprot.org/uniprot/Q8KGC5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/194439:AYT24_RS09405 ^@ http://purl.uniprot.org/uniprot/Q8KAS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/194439:AYT24_RS05280 ^@ http://purl.uniprot.org/uniprot/Q8KD88 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/194439:AYT24_RS06345 ^@ http://purl.uniprot.org/uniprot/Q8KCL3 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/194439:AYT24_RS10140 ^@ http://purl.uniprot.org/uniprot/Q8KAC5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/194439:AYT24_RS01275 ^@ http://purl.uniprot.org/uniprot/Q8KFR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS10375 ^@ http://purl.uniprot.org/uniprot/Q8KA81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/194439:AYT24_RS02780 ^@ http://purl.uniprot.org/uniprot/Q8KET9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/194439:AYT24_RS01605 ^@ http://purl.uniprot.org/uniprot/Q8KFK3 ^@ Cofactor|||Disruption Phenotype|||Function|||Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Involved in the biosynthesis of chlorobactene, a carotenoid with aromatic end group (PubMed:15292122). Catalyzes the introduction of two additional double bonds into the ionone ring of gamma-carotene to produce chlorobactene. The reaction includes an intramolecular methyl transfer from position C1 to position C2 of the ring (Probable).|||Mutant lacks chlorobactene and all its derivatives, and accumulates only gamma-carotene and its derivatives. The growth rate of the mutant shows no significant deviation from the wild-type growth rate at any light intensity. http://togogenome.org/gene/194439:AYT24_RS03040 ^@ http://purl.uniprot.org/uniprot/O68983 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Chlorosome|||Could play a direct role in the oxidation or reduction of the quenching species formed in the chlorosome. http://togogenome.org/gene/194439:AYT24_RS07355 ^@ http://purl.uniprot.org/uniprot/Q8KC00 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/194439:AYT24_RS04555 ^@ http://purl.uniprot.org/uniprot/Q8KDQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS08455 ^@ http://purl.uniprot.org/uniprot/Q8KBB8 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/194439:AYT24_RS07370 ^@ http://purl.uniprot.org/uniprot/Q8KBZ7 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/194439:AYT24_RS06105 ^@ http://purl.uniprot.org/uniprot/Q8KCR6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/194439:AYT24_RS07925 ^@ http://purl.uniprot.org/uniprot/Q8KBN0 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/194439:AYT24_RS08220 ^@ http://purl.uniprot.org/uniprot/Q8KBG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS07515 ^@ http://purl.uniprot.org/uniprot/Q8KBW5 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/194439:AYT24_RS08390 ^@ http://purl.uniprot.org/uniprot/Q8KBD4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00010 ^@ http://purl.uniprot.org/uniprot/Q8KGG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/194439:AYT24_RS08205 ^@ http://purl.uniprot.org/uniprot/Q8KBH2 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/194439:AYT24_RS05420 ^@ http://purl.uniprot.org/uniprot/Q8KD59 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/194439:AYT24_RS02945 ^@ http://purl.uniprot.org/uniprot/Q8KEQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06110 ^@ http://purl.uniprot.org/uniprot/Q8KCR5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/194439:AYT24_RS07835 ^@ http://purl.uniprot.org/uniprot/Q8KBP9 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/194439:AYT24_RS05945 ^@ http://purl.uniprot.org/uniprot/Q8KCU7 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/194439:AYT24_RS04455 ^@ http://purl.uniprot.org/uniprot/P59077 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/194439:AYT24_RS01345 ^@ http://purl.uniprot.org/uniprot/Q8KFQ2 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/194439:AYT24_RS08065 ^@ http://purl.uniprot.org/uniprot/Q8KBK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06950 ^@ http://purl.uniprot.org/uniprot/Q8KC87 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/194439:AYT24_RS06935 ^@ http://purl.uniprot.org/uniprot/Q8KC90 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/194439:AYT24_RS06275 ^@ http://purl.uniprot.org/uniprot/Q8KCN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS02855 ^@ http://purl.uniprot.org/uniprot/Q8KES2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01850 ^@ http://purl.uniprot.org/uniprot/Q8KFE7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/194439:AYT24_RS08250 ^@ http://purl.uniprot.org/uniprot/Q8KBG2 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/194439:AYT24_RS01875 ^@ http://purl.uniprot.org/uniprot/Q8KFE2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/194439:AYT24_RS08665 ^@ http://purl.uniprot.org/uniprot/Q8KB71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS00015 ^@ http://purl.uniprot.org/uniprot/Q8KGG5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/194439:AYT24_RS07050 ^@ http://purl.uniprot.org/uniprot/Q8KC67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS05135 ^@ http://purl.uniprot.org/uniprot/Q8KDC0 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/194439:AYT24_RS08180 ^@ http://purl.uniprot.org/uniprot/Q8KBH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/194439:AYT24_RS09635 ^@ http://purl.uniprot.org/uniprot/Q8KAM4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/194439:AYT24_RS00235 ^@ http://purl.uniprot.org/uniprot/Q8KGC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS01845 ^@ http://purl.uniprot.org/uniprot/Q8KFE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.|||Cell inner membrane|||Homodimer.|||Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. http://togogenome.org/gene/194439:AYT24_RS08095 ^@ http://purl.uniprot.org/uniprot/Q8KBJ5 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/194439:AYT24_RS01025 ^@ http://purl.uniprot.org/uniprot/Q8KFX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/194439:AYT24_RS09960 ^@ http://purl.uniprot.org/uniprot/Q8KAG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/194439:AYT24_RS07165 ^@ http://purl.uniprot.org/uniprot/Q8KC42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/194439:AYT24_RS04440 ^@ http://purl.uniprot.org/uniprot/Q8KDS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate (PubMed:25070637). Can also transaminate prephenate in the presence of aspartate (PubMed:25070637).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS04320 ^@ http://purl.uniprot.org/uniprot/Q8KDV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. http://togogenome.org/gene/194439:AYT24_RS05495 ^@ http://purl.uniprot.org/uniprot/Q8KD44 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/194439:AYT24_RS08770 ^@ http://purl.uniprot.org/uniprot/Q8KB52 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/194439:AYT24_RS09650 ^@ http://purl.uniprot.org/uniprot/Q8KAM1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/194439:AYT24_RS04810 ^@ http://purl.uniprot.org/uniprot/H2VFJ2 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/194439:AYT24_RS03915 ^@ http://purl.uniprot.org/uniprot/Q8KE52 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/194439:AYT24_RS01390 ^@ http://purl.uniprot.org/uniprot/Q8KFP2 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/194439:AYT24_RS07845 ^@ http://purl.uniprot.org/uniprot/Q8KBP7 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/194439:AYT24_RS04860 ^@ http://purl.uniprot.org/uniprot/Q8KDJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/194439:AYT24_RS05605 ^@ http://purl.uniprot.org/uniprot/Q8KD18 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||May bind 1 zinc ion per subunit.|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/194439:AYT24_RS10310 ^@ http://purl.uniprot.org/uniprot/Q8KA94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RlpA family.|||Cell membrane|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/194439:AYT24_RS06355 ^@ http://purl.uniprot.org/uniprot/Q8KCL0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS02195 ^@ http://purl.uniprot.org/uniprot/Q8KF76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/194439:AYT24_RS08195 ^@ http://purl.uniprot.org/uniprot/Q8KBH4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/194439:AYT24_RS05685 ^@ http://purl.uniprot.org/uniprot/Q8KCZ9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/194439:AYT24_RS09890 ^@ http://purl.uniprot.org/uniprot/Q8KAI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS09315 ^@ http://purl.uniprot.org/uniprot/Q46386 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BChl C/E-binding protein family.|||Component of the photosynthetic apparatus. The light harvesting B740 complex binds bacteriochlorophyll c.|||chlorosome envelope http://togogenome.org/gene/194439:AYT24_RS04845 ^@ http://purl.uniprot.org/uniprot/Q8KDJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09745 ^@ http://purl.uniprot.org/uniprot/Q9F716 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BchN/ChlN family.|||Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.|||Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits. http://togogenome.org/gene/194439:AYT24_RS09600 ^@ http://purl.uniprot.org/uniprot/Q8KAN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ChlB/BchB/BchZ family.|||Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.|||Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole. http://togogenome.org/gene/194439:AYT24_RS07500 ^@ http://purl.uniprot.org/uniprot/Q8KBW8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/194439:AYT24_RS08670 ^@ http://purl.uniprot.org/uniprot/Q8KB70 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/194439:AYT24_RS04025 ^@ http://purl.uniprot.org/uniprot/Q8KE25 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/194439:AYT24_RS09570 ^@ http://purl.uniprot.org/uniprot/Q8KAN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS10255 ^@ http://purl.uniprot.org/uniprot/Q8KAA4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/194439:AYT24_RS02675 ^@ http://purl.uniprot.org/uniprot/Q8KEW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06755 ^@ http://purl.uniprot.org/uniprot/Q8KCC7 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/194439:AYT24_RS07705 ^@ http://purl.uniprot.org/uniprot/Q8KBS3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/194439:AYT24_RS06845 ^@ http://purl.uniprot.org/uniprot/Q8KCB2 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS00730 ^@ http://purl.uniprot.org/uniprot/Q8KG22 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/194439:AYT24_RS03115 ^@ http://purl.uniprot.org/uniprot/Q8KEL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/194439:AYT24_RS07735 ^@ http://purl.uniprot.org/uniprot/Q8KBR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/194439:AYT24_RS07235 ^@ http://purl.uniprot.org/uniprot/Q8KC25 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/194439:AYT24_RS03975 ^@ http://purl.uniprot.org/uniprot/Q8KE37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrE/TusD family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS04345 ^@ http://purl.uniprot.org/uniprot/Q8KDU9 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/194439:AYT24_RS02190 ^@ http://purl.uniprot.org/uniprot/Q8KF78 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/194439:AYT24_RS05660 ^@ http://purl.uniprot.org/uniprot/Q8KD05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/194439:AYT24_RS09615 ^@ http://purl.uniprot.org/uniprot/Q8KAM8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/194439:AYT24_RS06925 ^@ http://purl.uniprot.org/uniprot/Q8KC92 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/194439:AYT24_RS05775 ^@ http://purl.uniprot.org/uniprot/Q8KCY0 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/194439:AYT24_RS02825 ^@ http://purl.uniprot.org/uniprot/Q8KES9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/194439:AYT24_RS00175 ^@ http://purl.uniprot.org/uniprot/Q8KGD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS08060 ^@ http://purl.uniprot.org/uniprot/Q8KBK3 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/194439:AYT24_RS00170 ^@ http://purl.uniprot.org/uniprot/Q8KGD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/194439:AYT24_RS07090 ^@ http://purl.uniprot.org/uniprot/Q8KC58 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/194439:AYT24_RS00075 ^@ http://purl.uniprot.org/uniprot/Q8KGF3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS09935 ^@ http://purl.uniprot.org/uniprot/Q8KAH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/194439:AYT24_RS06215 ^@ http://purl.uniprot.org/uniprot/Q8KCP0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/194439:AYT24_RS10260 ^@ http://purl.uniprot.org/uniprot/Q8KAA3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/194439:AYT24_RS03085 ^@ http://purl.uniprot.org/uniprot/Q8KEM4 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/194439:AYT24_RS09805 ^@ http://purl.uniprot.org/uniprot/Q8KAJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/194439:AYT24_RS09255 ^@ http://purl.uniprot.org/uniprot/Q8KAV2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/194439:AYT24_RS06715 ^@ http://purl.uniprot.org/uniprot/Q8KCD6 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/194439:AYT24_RS00640 ^@ http://purl.uniprot.org/uniprot/Q8KG34 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/194439:AYT24_RS09190 ^@ http://purl.uniprot.org/uniprot/Q8KAW6 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/194439:AYT24_RS08985 ^@ http://purl.uniprot.org/uniprot/Q8KB10 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/194439:AYT24_RS02900 ^@ http://purl.uniprot.org/uniprot/Q8KER4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS07680 ^@ http://purl.uniprot.org/uniprot/Q8KBS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS07950 ^@ http://purl.uniprot.org/uniprot/Q8KBM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00455 ^@ http://purl.uniprot.org/uniprot/Q8KG76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS05335 ^@ http://purl.uniprot.org/uniprot/Q8KD77 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS09855 ^@ http://purl.uniprot.org/uniprot/Q8KAI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/194439:AYT24_RS07260 ^@ http://purl.uniprot.org/uniprot/Q8KC19 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/194439:AYT24_RS04575 ^@ http://purl.uniprot.org/uniprot/Q8KDQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS03755 ^@ http://purl.uniprot.org/uniprot/Q8KE87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/194439:AYT24_RS03955 ^@ http://purl.uniprot.org/uniprot/Q8K5F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS04590 ^@ http://purl.uniprot.org/uniprot/Q8KDQ0 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/194439:AYT24_RS10040 ^@ http://purl.uniprot.org/uniprot/Q8KAE8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/194439:AYT24_RS07490 ^@ http://purl.uniprot.org/uniprot/Q8KBX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.|||Cytoplasm|||In the C-terminal section; belongs to the thioester dehydratase family.|||In the N-terminal section; belongs to the LpxC family.|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/194439:AYT24_RS03845 ^@ http://purl.uniprot.org/uniprot/Q8KE68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS09560 ^@ http://purl.uniprot.org/uniprot/Q8KAN9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09425 ^@ http://purl.uniprot.org/uniprot/Q8KAR7 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family.|||Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/194439:AYT24_RS04490 ^@ http://purl.uniprot.org/uniprot/Q8KDS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS05270 ^@ http://purl.uniprot.org/uniprot/Q8KD90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/194439:AYT24_RS09195 ^@ http://purl.uniprot.org/uniprot/Q8KAW5 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/194439:AYT24_RS08270 ^@ http://purl.uniprot.org/uniprot/Q8KBF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/194439:AYT24_RS04790 ^@ http://purl.uniprot.org/uniprot/Q8KDK5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/194439:AYT24_RS01405 ^@ http://purl.uniprot.org/uniprot/Q8KFN9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/194439:AYT24_RS06985 ^@ http://purl.uniprot.org/uniprot/Q8KC80 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/194439:AYT24_RS08245 ^@ http://purl.uniprot.org/uniprot/Q8KBG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS06705 ^@ http://purl.uniprot.org/uniprot/Q8KCD8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/194439:AYT24_RS06840 ^@ http://purl.uniprot.org/uniprot/Q8KCB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell inner membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/194439:AYT24_RS09795 ^@ http://purl.uniprot.org/uniprot/Q8KAJ8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/194439:AYT24_RS08045 ^@ http://purl.uniprot.org/uniprot/Q8KBK6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/194439:AYT24_RS07325 ^@ http://purl.uniprot.org/uniprot/Q8KC06 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/194439:AYT24_RS05995 ^@ http://purl.uniprot.org/uniprot/Q8KCT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS09955 ^@ http://purl.uniprot.org/uniprot/P59060 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/194439:AYT24_RS03005 ^@ http://purl.uniprot.org/uniprot/Q8KEP3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/194439:AYT24_RS09735 ^@ http://purl.uniprot.org/uniprot/Q9F714 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.|||Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. http://togogenome.org/gene/194439:AYT24_RS07040 ^@ http://purl.uniprot.org/uniprot/Q8KC69 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/194439:AYT24_RS09535 ^@ http://purl.uniprot.org/uniprot/Q8KAP4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/194439:AYT24_RS02170 ^@ http://purl.uniprot.org/uniprot/Q8KF83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS02685 ^@ http://purl.uniprot.org/uniprot/Q8KEW3 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/194439:AYT24_RS02660 ^@ http://purl.uniprot.org/uniprot/Q8KEW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/194439:AYT24_RS07430 ^@ http://purl.uniprot.org/uniprot/Q8KBY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS06555 ^@ http://purl.uniprot.org/uniprot/Q8KCH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/194439:AYT24_RS04545 ^@ http://purl.uniprot.org/uniprot/Q8KDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00610 ^@ http://purl.uniprot.org/uniprot/Q8KG41 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/194439:AYT24_RS07505 ^@ http://purl.uniprot.org/uniprot/Q8KBW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01280 ^@ http://purl.uniprot.org/uniprot/Q8KFR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01215 ^@ http://purl.uniprot.org/uniprot/Q8KFS6 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/194439:AYT24_RS00180 ^@ http://purl.uniprot.org/uniprot/Q8KGD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS02640 ^@ http://purl.uniprot.org/uniprot/Q8KEX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS09915 ^@ http://purl.uniprot.org/uniprot/Q8KAH6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/194439:AYT24_RS07530 ^@ http://purl.uniprot.org/uniprot/Q8KBW2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS01760 ^@ http://purl.uniprot.org/uniprot/Q8KFG6 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/194439:AYT24_RS03610 ^@ http://purl.uniprot.org/uniprot/Q8KEB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/194439:AYT24_RS07775 ^@ http://purl.uniprot.org/uniprot/Q8KBR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS08790 ^@ http://purl.uniprot.org/uniprot/Q46366 ^@ Function|||Similarity ^@ Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity).|||Belongs to the arsA ATPase family. http://togogenome.org/gene/194439:AYT24_RS09785 ^@ http://purl.uniprot.org/uniprot/Q8KAK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/194439:AYT24_RS00940 ^@ http://purl.uniprot.org/uniprot/Q8KFY5 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS01710 ^@ http://purl.uniprot.org/uniprot/Q8KFI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/194439:AYT24_RS06580 ^@ http://purl.uniprot.org/uniprot/Q8KCG7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/194439:AYT24_RS04315 ^@ http://purl.uniprot.org/uniprot/Q8KDV5 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/194439:AYT24_RS10130 ^@ http://purl.uniprot.org/uniprot/Q8KAC7 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/194439:AYT24_RS02515 ^@ http://purl.uniprot.org/uniprot/Q8KEZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/194439:AYT24_RS04565 ^@ http://purl.uniprot.org/uniprot/Q8KDQ5 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/194439:AYT24_RS00975 ^@ http://purl.uniprot.org/uniprot/Q8KFX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/194439:AYT24_RS00835 ^@ http://purl.uniprot.org/uniprot/Q8KG04 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS05275 ^@ http://purl.uniprot.org/uniprot/Q8KD89 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/194439:AYT24_RS01680 ^@ http://purl.uniprot.org/uniprot/Q8KFI7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/194439:AYT24_RS03725 ^@ http://purl.uniprot.org/uniprot/Q8KE92 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/194439:AYT24_RS04240 ^@ http://purl.uniprot.org/uniprot/Q8KDX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS05405 ^@ http://purl.uniprot.org/uniprot/Q8KD62 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/194439:AYT24_RS02540 ^@ http://purl.uniprot.org/uniprot/Q8KEZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS05285 ^@ http://purl.uniprot.org/uniprot/Q8KD87 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/194439:AYT24_RS00420 ^@ http://purl.uniprot.org/uniprot/Q8KG83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. http://togogenome.org/gene/194439:AYT24_RS06260 ^@ http://purl.uniprot.org/uniprot/Q8KCN2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/194439:AYT24_RS05870 ^@ http://purl.uniprot.org/uniprot/Q93SW0 ^@ Function|||Similarity ^@ Belongs to the Mg-chelatase subunits D/I family.|||Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. http://togogenome.org/gene/194439:AYT24_RS09910 ^@ http://purl.uniprot.org/uniprot/Q8KAH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/194439:AYT24_RS01195 ^@ http://purl.uniprot.org/uniprot/Q8KFT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/194439:AYT24_RS08900 ^@ http://purl.uniprot.org/uniprot/Q8KB29 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/194439:AYT24_RS09075 ^@ http://purl.uniprot.org/uniprot/Q8KAY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/194439:AYT24_RS05625 ^@ http://purl.uniprot.org/uniprot/Q8KD14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer. http://togogenome.org/gene/194439:AYT24_RS01755 ^@ http://purl.uniprot.org/uniprot/Q8KFG8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/194439:AYT24_RS09840 ^@ http://purl.uniprot.org/uniprot/Q8KAI9 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS00370 ^@ http://purl.uniprot.org/uniprot/Q8KG93 ^@ Function|||PTM ^@ Binds 1 heme c group covalently per subunit.|||This basic c-type monoheme cytochrome has been found exclusively in the green photosynthetic bacteria, although its role in bacterial photosynthesis is not established. It has an unusually low redox potential compared with mitochondrial cytochrome c. It is reactive with cytochrome c oxidases but not with reductases. http://togogenome.org/gene/194439:AYT24_RS06210 ^@ http://purl.uniprot.org/uniprot/Q8KCP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/194439:AYT24_RS00755 ^@ http://purl.uniprot.org/uniprot/Q8KG21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/194439:AYT24_RS04805 ^@ http://purl.uniprot.org/uniprot/O68986 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CsmB/CsmF family.|||chlorosome envelope http://togogenome.org/gene/194439:AYT24_RS06820 ^@ http://purl.uniprot.org/uniprot/P80039 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homotetramer; arranged as a dimer of dimers. http://togogenome.org/gene/194439:AYT24_RS09740 ^@ http://purl.uniprot.org/uniprot/Q9F715 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ChlB/BchB/BchZ family.|||Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.|||Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits. http://togogenome.org/gene/194439:AYT24_RS06745 ^@ http://purl.uniprot.org/uniprot/Q8KCC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/194439:AYT24_RS04290 ^@ http://purl.uniprot.org/uniprot/Q8KDW0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS04515 ^@ http://purl.uniprot.org/uniprot/Q8KDR5 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/194439:AYT24_RS05260 ^@ http://purl.uniprot.org/uniprot/Q8KD92 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/194439:AYT24_RS00470 ^@ http://purl.uniprot.org/uniprot/Q8KG73 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/194439:AYT24_RS08040 ^@ http://purl.uniprot.org/uniprot/Q8KBK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS08375 ^@ http://purl.uniprot.org/uniprot/Q8KBD7 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/194439:AYT24_RS04125 ^@ http://purl.uniprot.org/uniprot/Q8KDZ9 ^@ Function|||Similarity ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane. http://togogenome.org/gene/194439:AYT24_RS07110 ^@ http://purl.uniprot.org/uniprot/Q8KC53 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS02390 ^@ http://purl.uniprot.org/uniprot/Q8KF33 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/194439:AYT24_RS08240 ^@ http://purl.uniprot.org/uniprot/Q8KBG4 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/194439:AYT24_RS09655 ^@ http://purl.uniprot.org/uniprot/Q8KAM0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/194439:AYT24_RS01055 ^@ http://purl.uniprot.org/uniprot/Q8KFW4 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/194439:AYT24_RS09800 ^@ http://purl.uniprot.org/uniprot/P59129 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/194439:AYT24_RS08105 ^@ http://purl.uniprot.org/uniprot/Q8KBJ3 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/194439:AYT24_RS04150 ^@ http://purl.uniprot.org/uniprot/Q8KDZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/194439:AYT24_RS09760 ^@ http://purl.uniprot.org/uniprot/Q8KAK5 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/194439:AYT24_RS02490 ^@ http://purl.uniprot.org/uniprot/Q8KF03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/194439:AYT24_RS02400 ^@ http://purl.uniprot.org/uniprot/Q8KF30 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/194439:AYT24_RS06940 ^@ http://purl.uniprot.org/uniprot/Q8KC89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/194439:AYT24_RS04005 ^@ http://purl.uniprot.org/uniprot/Q8KE30 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/194439:AYT24_RS00275 ^@ http://purl.uniprot.org/uniprot/Q8KGB3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/194439:AYT24_RS05865 ^@ http://purl.uniprot.org/uniprot/H2VFJ9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunit H family. http://togogenome.org/gene/194439:AYT24_RS05610 ^@ http://purl.uniprot.org/uniprot/Q8KD17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/194439:AYT24_RS06665 ^@ http://purl.uniprot.org/uniprot/Q8KCE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS06735 ^@ http://purl.uniprot.org/uniprot/Q8KCD1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06595 ^@ http://purl.uniprot.org/uniprot/Q8KCG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09180 ^@ http://purl.uniprot.org/uniprot/Q8KAW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12) (By similarity).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/194439:AYT24_RS08120 ^@ http://purl.uniprot.org/uniprot/Q8KBJ0 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/194439:AYT24_RS02420 ^@ http://purl.uniprot.org/uniprot/Q8KF21 ^@ Similarity ^@ Belongs to the DNA photolyase class-2 family. http://togogenome.org/gene/194439:AYT24_RS09940 ^@ http://purl.uniprot.org/uniprot/Q8KAH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS08865 ^@ http://purl.uniprot.org/uniprot/Q8KB35 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/194439:AYT24_RS03595 ^@ http://purl.uniprot.org/uniprot/Q8KEC2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS03025 ^@ http://purl.uniprot.org/uniprot/Q8KEN8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/194439:AYT24_RS09830 ^@ http://purl.uniprot.org/uniprot/Q8KAJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/194439:AYT24_RS01540 ^@ http://purl.uniprot.org/uniprot/Q8KFL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/194439:AYT24_RS10095 ^@ http://purl.uniprot.org/uniprot/Q8KAD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS03880 ^@ http://purl.uniprot.org/uniprot/Q8KE61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/194439:AYT24_RS09995 ^@ http://purl.uniprot.org/uniprot/Q8KAF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS07445 ^@ http://purl.uniprot.org/uniprot/Q8KBY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS05400 ^@ http://purl.uniprot.org/uniprot/Q8KD63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01220 ^@ http://purl.uniprot.org/uniprot/Q8KFS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/194439:AYT24_RS01245 ^@ http://purl.uniprot.org/uniprot/Q8KFS0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/194439:AYT24_RS03720 ^@ http://purl.uniprot.org/uniprot/Q8KE93 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/194439:AYT24_RS07585 ^@ http://purl.uniprot.org/uniprot/Q8KBV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01180 ^@ http://purl.uniprot.org/uniprot/Q8KFT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/194439:AYT24_RS08355 ^@ http://purl.uniprot.org/uniprot/Q8KBE1 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/194439:AYT24_RS04985 ^@ http://purl.uniprot.org/uniprot/Q8KDG1 ^@ Similarity ^@ In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.|||In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. http://togogenome.org/gene/194439:AYT24_RS04875 ^@ http://purl.uniprot.org/uniprot/Q8KDI7 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/194439:AYT24_RS08300 ^@ http://purl.uniprot.org/uniprot/Q8KBF3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/194439:AYT24_RS01060 ^@ http://purl.uniprot.org/uniprot/Q8KFW3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS09185 ^@ http://purl.uniprot.org/uniprot/Q8KAW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09085 ^@ http://purl.uniprot.org/uniprot/Q8KAY6 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/194439:AYT24_RS01355 ^@ http://purl.uniprot.org/uniprot/Q8KFP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09430 ^@ http://purl.uniprot.org/uniprot/Q8KAR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/194439:AYT24_RS01790 ^@ http://purl.uniprot.org/uniprot/P59316 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/194439:AYT24_RS05115 ^@ http://purl.uniprot.org/uniprot/Q8KDC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/194439:AYT24_RS10200 ^@ http://purl.uniprot.org/uniprot/Q8K5F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS08050 ^@ http://purl.uniprot.org/uniprot/Q8KBK5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/194439:AYT24_RS08800 ^@ http://purl.uniprot.org/uniprot/Q8KB47 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/194439:AYT24_RS08130 ^@ http://purl.uniprot.org/uniprot/Q8KBI8 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/194439:AYT24_RS07250 ^@ http://purl.uniprot.org/uniprot/Q8KC21 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/194439:AYT24_RS00100 ^@ http://purl.uniprot.org/uniprot/Q8KGE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity). http://togogenome.org/gene/194439:AYT24_RS09105 ^@ http://purl.uniprot.org/uniprot/Q8KAY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06200 ^@ http://purl.uniprot.org/uniprot/Q8KCP5 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/194439:AYT24_RS09160 ^@ http://purl.uniprot.org/uniprot/Q8KAX3 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/194439:AYT24_RS03120 ^@ http://purl.uniprot.org/uniprot/Q8KEL8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/194439:AYT24_RS05035 ^@ http://purl.uniprot.org/uniprot/Q8KDF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09170 ^@ http://purl.uniprot.org/uniprot/Q8KAX1 ^@ Similarity ^@ In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/194439:AYT24_RS07115 ^@ http://purl.uniprot.org/uniprot/Q8KC52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS09835 ^@ http://purl.uniprot.org/uniprot/Q8KAJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS08460 ^@ http://purl.uniprot.org/uniprot/Q8KBB6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS01580 ^@ http://purl.uniprot.org/uniprot/Q8KFK8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS04505 ^@ http://purl.uniprot.org/uniprot/Q8KDR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06285 ^@ http://purl.uniprot.org/uniprot/Q8KCM7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS02320 ^@ http://purl.uniprot.org/uniprot/Q8KF51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00930 ^@ http://purl.uniprot.org/uniprot/Q8KFY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00635 ^@ http://purl.uniprot.org/uniprot/Q8KG35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS07785 ^@ http://purl.uniprot.org/uniprot/Q8KBQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS07700 ^@ http://purl.uniprot.org/uniprot/Q8KBS4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/194439:AYT24_RS09825 ^@ http://purl.uniprot.org/uniprot/Q8KAJ2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/194439:AYT24_RS04970 ^@ http://purl.uniprot.org/uniprot/Q8KDG5 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/194439:AYT24_RS08525 ^@ http://purl.uniprot.org/uniprot/Q8KBA3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS04950 ^@ http://purl.uniprot.org/uniprot/Q8KDH2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS04350 ^@ http://purl.uniprot.org/uniprot/Q8KDU8 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/194439:AYT24_RS08750 ^@ http://purl.uniprot.org/uniprot/Q8KB56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/194439:AYT24_RS10280 ^@ http://purl.uniprot.org/uniprot/Q8KAA1 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/194439:AYT24_RS01945 ^@ http://purl.uniprot.org/uniprot/Q8KFC8 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/194439:AYT24_RS06465 ^@ http://purl.uniprot.org/uniprot/Q8KCJ3 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/194439:AYT24_RS00800 ^@ http://purl.uniprot.org/uniprot/Q8KG12 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/194439:AYT24_RS07015 ^@ http://purl.uniprot.org/uniprot/Q8KC74 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/194439:AYT24_RS05540 ^@ http://purl.uniprot.org/uniprot/Q8KD34 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/194439:AYT24_RS05350 ^@ http://purl.uniprot.org/uniprot/Q8KD74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/194439:AYT24_RS02205 ^@ http://purl.uniprot.org/uniprot/Q8KF74 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/194439:AYT24_RS03415 ^@ http://purl.uniprot.org/uniprot/Q8KEF9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/194439:AYT24_RS06975 ^@ http://purl.uniprot.org/uniprot/Q8KC82 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/194439:AYT24_RS10025 ^@ http://purl.uniprot.org/uniprot/P59599 ^@ Similarity ^@ Belongs to the acetyltransferase family. http://togogenome.org/gene/194439:AYT24_RS01515 ^@ http://purl.uniprot.org/uniprot/Q8KFM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS00770 ^@ http://purl.uniprot.org/uniprot/Q8KG18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/194439:AYT24_RS08575 ^@ http://purl.uniprot.org/uniprot/Q8KB93 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/194439:AYT24_RS07550 ^@ http://purl.uniprot.org/uniprot/Q8KBV8 ^@ Cofactor|||Similarity ^@ Belongs to the GARS family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/194439:AYT24_RS05960 ^@ http://purl.uniprot.org/uniprot/Q8KCU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/194439:AYT24_RS05545 ^@ http://purl.uniprot.org/uniprot/Q8KD33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS00145 ^@ http://purl.uniprot.org/uniprot/Q8KGD9 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/194439:AYT24_RS01205 ^@ http://purl.uniprot.org/uniprot/Q8KFS8 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/194439:AYT24_RS00375 ^@ http://purl.uniprot.org/uniprot/Q8KG92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01775 ^@ http://purl.uniprot.org/uniprot/Q8KFG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS02995 ^@ http://purl.uniprot.org/uniprot/Q8KEP5 ^@ Subunit ^@ Component of the P840 reaction center. http://togogenome.org/gene/194439:AYT24_RS07400 ^@ http://purl.uniprot.org/uniprot/O07091 ^@ Function|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 1 heme group per subunit.|||Cell inner membrane|||Monoheme cytochrome which is the immediate electron donor to P840 of the photosynthetic reaction center complex.|||Monomer (PubMed:20156447). Component of the photosynthetic reaction center composed of protein subunits PscA, PscC, PscB and PscD. The reaction center interacts with FmoA (which forms the Fenna-Matthews-Olson (FMO) complex). The reaction center/FmoA complex has two PscA subunits, one PscB and one PscD subunit, probably two FmoA complexes and at least one PscC subunit (PubMed:10398586). http://togogenome.org/gene/194439:AYT24_RS05060 ^@ http://purl.uniprot.org/uniprot/P59611 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/194439:AYT24_RS00795 ^@ http://purl.uniprot.org/uniprot/Q8KG13 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/194439:AYT24_RS01495 ^@ http://purl.uniprot.org/uniprot/Q9F722 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Cell inner membrane|||Component of the green S-bacteria bc-complex which consists of the Rieske protein and cytochrome b subunit and which appears to lack a cytochrome c1-equivalent. This complex has a comparatively low redox potential.|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/194439:AYT24_RS02370 ^@ http://purl.uniprot.org/uniprot/Q8KF38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS07420 ^@ http://purl.uniprot.org/uniprot/Q8KBY8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/194439:AYT24_RS10120 ^@ http://purl.uniprot.org/uniprot/Q8KAC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/194439:AYT24_RS00210 ^@ http://purl.uniprot.org/uniprot/Q8KGC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/194439:AYT24_RS09930 ^@ http://purl.uniprot.org/uniprot/Q8KAH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS09610 ^@ http://purl.uniprot.org/uniprot/Q8KAM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/194439:AYT24_RS05695 ^@ http://purl.uniprot.org/uniprot/Q8KCZ7 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/194439:AYT24_RS05825 ^@ http://purl.uniprot.org/uniprot/Q8KCW9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/194439:AYT24_RS10125 ^@ http://purl.uniprot.org/uniprot/Q8KAC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/194439:AYT24_RS07275 ^@ http://purl.uniprot.org/uniprot/H2VFJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS06955 ^@ http://purl.uniprot.org/uniprot/Q8KC86 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/194439:AYT24_RS01825 ^@ http://purl.uniprot.org/uniprot/Q8KFF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS06165 ^@ http://purl.uniprot.org/uniprot/Q8KCQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/194439:AYT24_RS07005 ^@ http://purl.uniprot.org/uniprot/Q8KC75 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/194439:AYT24_RS08345 ^@ http://purl.uniprot.org/uniprot/Q8KBE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/194439:AYT24_RS08295 ^@ http://purl.uniprot.org/uniprot/Q8KBF4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/194439:AYT24_RS05070 ^@ http://purl.uniprot.org/uniprot/Q8KDE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks the conserved threonine and leucine residues in positions 66 and 276, respectively, which are part of the carbamoylphosphate and ornithine binding sites; they are replaced by a leucine and a methionine residue, respectively.|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/194439:AYT24_RS00510 ^@ http://purl.uniprot.org/uniprot/Q8KG63 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/194439:AYT24_RS05030 ^@ http://purl.uniprot.org/uniprot/P58993 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Monomer.|||Serves as an electron acceptor for pyruvate ferredoxin oxidoreductase (PFOR). http://togogenome.org/gene/194439:AYT24_RS06960 ^@ http://purl.uniprot.org/uniprot/Q8KC85 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. NifB family.|||Binds 3 [4Fe-4S] clusters per monomer. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. The two others probably act as substrate.|||Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.|||Monomer. http://togogenome.org/gene/194439:AYT24_RS01210 ^@ http://purl.uniprot.org/uniprot/Q8KFS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/194439:AYT24_RS06640 ^@ http://purl.uniprot.org/uniprot/Q8KCF2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS05080 ^@ http://purl.uniprot.org/uniprot/Q8KDE0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/194439:AYT24_RS07330 ^@ http://purl.uniprot.org/uniprot/Q8KC05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/194439:AYT24_RS05325 ^@ http://purl.uniprot.org/uniprot/Q8KD79 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/194439:AYT24_RS02890 ^@ http://purl.uniprot.org/uniprot/Q8KER6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/194439:AYT24_RS00065 ^@ http://purl.uniprot.org/uniprot/Q8KGF5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/194439:AYT24_RS01965 ^@ http://purl.uniprot.org/uniprot/Q8KFC3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/194439:AYT24_RS06040 ^@ http://purl.uniprot.org/uniprot/P59038 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/194439:AYT24_RS01690 ^@ http://purl.uniprot.org/uniprot/Q8KFI4 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/194439:AYT24_RS03300 ^@ http://purl.uniprot.org/uniprot/Q8KEI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06295 ^@ http://purl.uniprot.org/uniprot/Q8KCM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09790 ^@ http://purl.uniprot.org/uniprot/Q8KAJ9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/194439:AYT24_RS06180 ^@ http://purl.uniprot.org/uniprot/Q8KCP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS05440 ^@ http://purl.uniprot.org/uniprot/Q8KD55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01550 ^@ http://purl.uniprot.org/uniprot/Q8KFL3 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/194439:AYT24_RS06265 ^@ http://purl.uniprot.org/uniprot/O68988 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Chlorosome|||Could play a direct role in the oxidation or reduction of the quenching species formed in the chlorosome. http://togogenome.org/gene/194439:AYT24_RS09605 ^@ http://purl.uniprot.org/uniprot/Q8KAN0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS04480 ^@ http://purl.uniprot.org/uniprot/Q8KDS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/194439:AYT24_RS06460 ^@ http://purl.uniprot.org/uniprot/Q8KCJ4 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/194439:AYT24_RS00185 ^@ http://purl.uniprot.org/uniprot/Q8KGD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane http://togogenome.org/gene/194439:AYT24_RS08745 ^@ http://purl.uniprot.org/uniprot/Q8KB57 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/194439:AYT24_RS01570 ^@ http://purl.uniprot.org/uniprot/Q8KFL0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/194439:AYT24_RS07450 ^@ http://purl.uniprot.org/uniprot/Q8KBY0 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/194439:AYT24_RS06815 ^@ http://purl.uniprot.org/uniprot/Q8KCB7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/194439:AYT24_RS00150 ^@ http://purl.uniprot.org/uniprot/Q8KGD8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS08910 ^@ http://purl.uniprot.org/uniprot/Q8KB27 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/194439:AYT24_RS00595 ^@ http://purl.uniprot.org/uniprot/Q8KG43 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/194439:AYT24_RS01490 ^@ http://purl.uniprot.org/uniprot/Q9F723 ^@ Similarity ^@ Belongs to the CrtC hydratase family. http://togogenome.org/gene/194439:AYT24_RS05955 ^@ http://purl.uniprot.org/uniprot/Q8KCU5 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/194439:AYT24_RS05010 ^@ http://purl.uniprot.org/uniprot/Q8KDF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS08730 ^@ http://purl.uniprot.org/uniprot/O52393 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS02560 ^@ http://purl.uniprot.org/uniprot/Q8KEY6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/194439:AYT24_RS02555 ^@ http://purl.uniprot.org/uniprot/Q8KEY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/194439:AYT24_RS09925 ^@ http://purl.uniprot.org/uniprot/Q8KAH4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/194439:AYT24_RS02655 ^@ http://purl.uniprot.org/uniprot/Q8KEW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06650 ^@ http://purl.uniprot.org/uniprot/Q8KCF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00590 ^@ http://purl.uniprot.org/uniprot/Q8KG44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS01640 ^@ http://purl.uniprot.org/uniprot/Q8KFJ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/194439:AYT24_RS02295 ^@ http://purl.uniprot.org/uniprot/Q8KF56 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/194439:AYT24_RS09205 ^@ http://purl.uniprot.org/uniprot/Q8KAW3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/194439:AYT24_RS01265 ^@ http://purl.uniprot.org/uniprot/Q8KFR6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/194439:AYT24_RS09175 ^@ http://purl.uniprot.org/uniprot/Q8KAW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/194439:AYT24_RS04140 ^@ http://purl.uniprot.org/uniprot/Q8KDZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS02530 ^@ http://purl.uniprot.org/uniprot/Q8KEZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS07160 ^@ http://purl.uniprot.org/uniprot/Q8KC43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/194439:AYT24_RS01665 ^@ http://purl.uniprot.org/uniprot/Q8KFJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS06790 ^@ http://purl.uniprot.org/uniprot/Q8KCC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS10060 ^@ http://purl.uniprot.org/uniprot/Q8KAE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09210 ^@ http://purl.uniprot.org/uniprot/Q8KAW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS04520 ^@ http://purl.uniprot.org/uniprot/Q8KDR4 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/194439:AYT24_RS04895 ^@ http://purl.uniprot.org/uniprot/Q8KDI2 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/194439:AYT24_RS02495 ^@ http://purl.uniprot.org/uniprot/Q8KF02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/194439:AYT24_RS08520 ^@ http://purl.uniprot.org/uniprot/Q8KBA4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS02040 ^@ http://purl.uniprot.org/uniprot/Q8KFA6 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/194439:AYT24_RS00105 ^@ http://purl.uniprot.org/uniprot/Q8KGE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00460 ^@ http://purl.uniprot.org/uniprot/Q8KG75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/194439:AYT24_RS09545 ^@ http://purl.uniprot.org/uniprot/Q8KAP2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/194439:AYT24_RS03660 ^@ http://purl.uniprot.org/uniprot/Q8KEA8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/194439:AYT24_RS04990 ^@ http://purl.uniprot.org/uniprot/Q8KDG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/194439:AYT24_RS05750 ^@ http://purl.uniprot.org/uniprot/Q8KCY5 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/194439:AYT24_RS07190 ^@ http://purl.uniprot.org/uniprot/Q8KC36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS10250 ^@ http://purl.uniprot.org/uniprot/Q8KAA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/194439:AYT24_RS06945 ^@ http://purl.uniprot.org/uniprot/Q8KC88 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/194439:AYT24_RS00125 ^@ http://purl.uniprot.org/uniprot/Q8KGE4 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS08370 ^@ http://purl.uniprot.org/uniprot/Q8KBD8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/194439:AYT24_RS00555 ^@ http://purl.uniprot.org/uniprot/Q8KG54 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/194439:AYT24_RS06375 ^@ http://purl.uniprot.org/uniprot/Q8KCK5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/194439:AYT24_RS03245 ^@ http://purl.uniprot.org/uniprot/Q8KEJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/194439:AYT24_RS02860 ^@ http://purl.uniprot.org/uniprot/Q8KES1 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/194439:AYT24_RS09755 ^@ http://purl.uniprot.org/uniprot/Q8KAK6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/194439:AYT24_RS06545 ^@ http://purl.uniprot.org/uniprot/Q8KCH5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/194439:AYT24_RS06445 ^@ http://purl.uniprot.org/uniprot/Q8KCJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS06680 ^@ http://purl.uniprot.org/uniprot/Q8KCE5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/194439:AYT24_RS00130 ^@ http://purl.uniprot.org/uniprot/Q8KGE2 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/194439:AYT24_RS01415 ^@ http://purl.uniprot.org/uniprot/Q8KFN7 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/194439:AYT24_RS03930 ^@ http://purl.uniprot.org/uniprot/Q8KE49 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family.|||Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. http://togogenome.org/gene/194439:AYT24_RS02985 ^@ http://purl.uniprot.org/uniprot/Q8KEP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane http://togogenome.org/gene/194439:AYT24_RS05965 ^@ http://purl.uniprot.org/uniprot/Q8KCU3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/194439:AYT24_RS08280 ^@ http://purl.uniprot.org/uniprot/Q8KBF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS07120 ^@ http://purl.uniprot.org/uniprot/Q8KC51 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/194439:AYT24_RS02565 ^@ http://purl.uniprot.org/uniprot/Q8KEY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/194439:AYT24_RS04270 ^@ http://purl.uniprot.org/uniprot/Q8KDW5 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/194439:AYT24_RS07020 ^@ http://purl.uniprot.org/uniprot/Q8KC73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/194439:AYT24_RS04310 ^@ http://purl.uniprot.org/uniprot/Q8KDV6 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/194439:AYT24_RS01410 ^@ http://purl.uniprot.org/uniprot/Q8KFN8 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/194439:AYT24_RS09900 ^@ http://purl.uniprot.org/uniprot/Q8KAH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS09480 ^@ http://purl.uniprot.org/uniprot/Q8KAQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS01185 ^@ http://purl.uniprot.org/uniprot/Q8KFT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/194439:AYT24_RS01635 ^@ http://purl.uniprot.org/uniprot/Q8KFJ7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane http://togogenome.org/gene/194439:AYT24_RS03470 ^@ http://purl.uniprot.org/uniprot/Q8KEE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS04370 ^@ http://purl.uniprot.org/uniprot/Q8KDU4 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/194439:AYT24_RS03345 ^@ http://purl.uniprot.org/uniprot/Q8KEH1 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/194439:AYT24_RS07345 ^@ http://purl.uniprot.org/uniprot/Q8KC02 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/194439:AYT24_RS00810 ^@ http://purl.uniprot.org/uniprot/Q8KG10 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/194439:AYT24_RS05375 ^@ http://purl.uniprot.org/uniprot/Q8KD69 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS08235 ^@ http://purl.uniprot.org/uniprot/Q8KBG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS10360 ^@ http://purl.uniprot.org/uniprot/Q8KA83 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/194439:AYT24_RS07270 ^@ http://purl.uniprot.org/uniprot/Q8KC17 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS00050 ^@ http://purl.uniprot.org/uniprot/Q8KGF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/194439:AYT24_RS01910 ^@ http://purl.uniprot.org/uniprot/Q8KFD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS04560 ^@ http://purl.uniprot.org/uniprot/Q8KDQ6 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/194439:AYT24_RS04760 ^@ http://purl.uniprot.org/uniprot/Q8KDL1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/194439:AYT24_RS07335 ^@ http://purl.uniprot.org/uniprot/Q8KC04 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/194439:AYT24_RS04690 ^@ http://purl.uniprot.org/uniprot/Q8KDM7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SoxA family.|||Binds 1 heme group per subunit.|||C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation.|||Cysteine persulfide at Cys-247.|||Heterodimer of SoxA and SoxX. The SoxAX complex interacts with CT1020, SoxAX-binding protein SaxB (SoxK); this interaction seems to be between SoxA and CT1020 and stimulates catalytic activity of the SoxAX complex.|||Periplasm http://togogenome.org/gene/194439:AYT24_RS02895 ^@ http://purl.uniprot.org/uniprot/Q8KER5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/194439:AYT24_RS09295 ^@ http://purl.uniprot.org/uniprot/Q8KAU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS04930 ^@ http://purl.uniprot.org/uniprot/Q8KDH6 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/194439:AYT24_RS03185 ^@ http://purl.uniprot.org/uniprot/Q8KEK4 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/194439:AYT24_RS00560 ^@ http://purl.uniprot.org/uniprot/Q8KG52 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/194439:AYT24_RS03830 ^@ http://purl.uniprot.org/uniprot/Q8KE72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/194439:AYT24_RS05075 ^@ http://purl.uniprot.org/uniprot/Q8KDE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/194439:AYT24_RS09860 ^@ http://purl.uniprot.org/uniprot/P59031 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/194439:AYT24_RS04435 ^@ http://purl.uniprot.org/uniprot/Q8KDS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/194439:AYT24_RS00025 ^@ http://purl.uniprot.org/uniprot/Q8KGG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/194439:AYT24_RS07300 ^@ http://purl.uniprot.org/uniprot/Q93SU4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/194439:AYT24_RS10240 ^@ http://purl.uniprot.org/uniprot/Q8KAA7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/194439:AYT24_RS04835 ^@ http://purl.uniprot.org/uniprot/Q8KDJ7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/194439:AYT24_RS05880 ^@ http://purl.uniprot.org/uniprot/Q8KCW2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Homodimer.|||Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/194439:AYT24_RS03435 ^@ http://purl.uniprot.org/uniprot/Q8KEF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/194439:AYT24_RS08840 ^@ http://purl.uniprot.org/uniprot/Q8KB39 ^@ Similarity ^@ Belongs to the Mg-chelatase subunit H family. http://togogenome.org/gene/194439:AYT24_RS07540 ^@ http://purl.uniprot.org/uniprot/Q8KBW0 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/194439:AYT24_RS01045 ^@ http://purl.uniprot.org/uniprot/Q8KFW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/194439:AYT24_RS05855 ^@ http://purl.uniprot.org/uniprot/Q8KCW4 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/194439:AYT24_RS05780 ^@ http://purl.uniprot.org/uniprot/Q8KCX9 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/194439:AYT24_RS02650 ^@ http://purl.uniprot.org/uniprot/Q8KEX0 ^@ Cofactor|||Similarity ^@ Belongs to the PdaD family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/194439:AYT24_RS07170 ^@ http://purl.uniprot.org/uniprot/Q8KC41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/194439:AYT24_RS08780 ^@ http://purl.uniprot.org/uniprot/P0A314 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BChl C/E-binding protein family.|||Component of the photosynthetic apparatus. The light harvesting B740 complex binds bacteriochlorophyll c.|||chlorosome envelope http://togogenome.org/gene/194439:AYT24_RS09865 ^@ http://purl.uniprot.org/uniprot/Q8KAI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/194439:AYT24_RS00245 ^@ http://purl.uniprot.org/uniprot/Q8KGB9 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/194439:AYT24_RS10350 ^@ http://purl.uniprot.org/uniprot/Q8KA85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits (By similarity).|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/194439:AYT24_RS05365 ^@ http://purl.uniprot.org/uniprot/Q8KD71 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/194439:AYT24_RS06710 ^@ http://purl.uniprot.org/uniprot/Q8KCD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/194439:AYT24_RS04750 ^@ http://purl.uniprot.org/uniprot/Q8KDL3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/194439:AYT24_RS02110 ^@ http://purl.uniprot.org/uniprot/Q8KF91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS08230 ^@ http://purl.uniprot.org/uniprot/Q8KBG6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS02830 ^@ http://purl.uniprot.org/uniprot/Q8KES8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/194439:AYT24_RS00330 ^@ http://purl.uniprot.org/uniprot/Q8KGA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS09920 ^@ http://purl.uniprot.org/uniprot/Q8KAH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/194439:AYT24_RS05875 ^@ http://purl.uniprot.org/uniprot/Q93SW1 ^@ Function|||Similarity ^@ Belongs to the Mg-chelatase subunits D/I family.|||Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. http://togogenome.org/gene/194439:AYT24_RS01480 ^@ http://purl.uniprot.org/uniprot/Q9F724 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS08285 ^@ http://purl.uniprot.org/uniprot/Q8KBF6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS02300 ^@ http://purl.uniprot.org/uniprot/Q8KF55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01285 ^@ http://purl.uniprot.org/uniprot/Q8KFR2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/194439:AYT24_RS05395 ^@ http://purl.uniprot.org/uniprot/Q8KD64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/194439:AYT24_RS03440 ^@ http://purl.uniprot.org/uniprot/Q8KEF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09445 ^@ http://purl.uniprot.org/uniprot/Q8KAR4 ^@ Similarity|||Subunit ^@ Belongs to the ADPRibase-Mn family.|||Monomer. http://togogenome.org/gene/194439:AYT24_RS08330 ^@ http://purl.uniprot.org/uniprot/Q8KBE7 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/194439:AYT24_RS00805 ^@ http://purl.uniprot.org/uniprot/Q8KG11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/194439:AYT24_RS02835 ^@ http://purl.uniprot.org/uniprot/Q8KES7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/194439:AYT24_RS04020 ^@ http://purl.uniprot.org/uniprot/Q8KE26 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/194439:AYT24_RS02235 ^@ http://purl.uniprot.org/uniprot/Q8KF68 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06990 ^@ http://purl.uniprot.org/uniprot/Q8KC79 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/194439:AYT24_RS06070 ^@ http://purl.uniprot.org/uniprot/Q8KCS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/194439:AYT24_RS02865 ^@ http://purl.uniprot.org/uniprot/Q8KES0 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/194439:AYT24_RS00625 ^@ http://purl.uniprot.org/uniprot/Q8KG37 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/194439:AYT24_RS00675 ^@ http://purl.uniprot.org/uniprot/Q8KG27 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/194439:AYT24_RS04815 ^@ http://purl.uniprot.org/uniprot/O68984 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/194439:AYT24_RS09815 ^@ http://purl.uniprot.org/uniprot/Q8KAJ4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/194439:AYT24_RS02130 ^@ http://purl.uniprot.org/uniprot/Q8KF88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS10235 ^@ http://purl.uniprot.org/uniprot/Q8KAA8 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/194439:AYT24_RS03480 ^@ http://purl.uniprot.org/uniprot/Q8KEE5 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/194439:AYT24_RS07955 ^@ http://purl.uniprot.org/uniprot/Q8KBM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS05225 ^@ http://purl.uniprot.org/uniprot/Q8KD99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS01590 ^@ http://purl.uniprot.org/uniprot/Q8KFK6 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/194439:AYT24_RS02645 ^@ http://purl.uniprot.org/uniprot/Q8KEX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS00765 ^@ http://purl.uniprot.org/uniprot/Q8KG19 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/194439:AYT24_RS04180 ^@ http://purl.uniprot.org/uniprot/Q8KDY6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/194439:AYT24_RS07125 ^@ http://purl.uniprot.org/uniprot/Q8KC50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS04725 ^@ http://purl.uniprot.org/uniprot/Q8KDL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/194439:AYT24_RS07410 ^@ http://purl.uniprot.org/uniprot/Q8KBZ1 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/194439:AYT24_RS06780 ^@ http://purl.uniprot.org/uniprot/Q46393 ^@ Function|||Subunit ^@ Homotrimer. Each subunit contains 7 molecules of bacteriochlorophyll a.|||Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers. http://togogenome.org/gene/194439:AYT24_RS00140 ^@ http://purl.uniprot.org/uniprot/Q8KGE0 ^@ Disruption Phenotype|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.|||Cells lacking this gene produce only bacteriochlorophyll d (BChld).|||Homodimer.|||Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities (PubMed:15090495). Catalyzes the methylation at the C-20 position of the cyclic tetrapyrrole chlorin of bacteriochlorophyll d (BChld) to produce bacteriochlorophyll c (BChlc) using S-adenosylmethionine (SAM) as a methyl source (PubMed:15090495, PubMed:16797589). http://togogenome.org/gene/194439:AYT24_RS03770 ^@ http://purl.uniprot.org/uniprot/Q8KE84 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/194439:AYT24_RS04620 ^@ http://purl.uniprot.org/uniprot/Q8KDP2 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/194439:AYT24_RS01585 ^@ http://purl.uniprot.org/uniprot/Q8KFK7 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS06065 ^@ http://purl.uniprot.org/uniprot/Q8KCS5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/194439:AYT24_RS02620 ^@ http://purl.uniprot.org/uniprot/Q8KEX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS10030 ^@ http://purl.uniprot.org/uniprot/Q8KAF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS00870 ^@ http://purl.uniprot.org/uniprot/Q8KFZ7 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/194439:AYT24_RS06485 ^@ http://purl.uniprot.org/uniprot/Q8KCI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/194439:AYT24_RS00280 ^@ http://purl.uniprot.org/uniprot/Q8KGB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/194439:AYT24_RS08785 ^@ http://purl.uniprot.org/uniprot/Q46367 ^@ Subcellular Location Annotation ^@ Chlorosome http://togogenome.org/gene/194439:AYT24_RS08175 ^@ http://purl.uniprot.org/uniprot/Q8KBH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/194439:AYT24_RS07285 ^@ http://purl.uniprot.org/uniprot/H2VFJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/194439:AYT24_RS02980 ^@ http://purl.uniprot.org/uniprot/Q8KEQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TolB family.|||Periplasm http://togogenome.org/gene/194439:AYT24_RS05185 ^@ http://purl.uniprot.org/uniprot/Q8KDA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/194439:AYT24_RS09165 ^@ http://purl.uniprot.org/uniprot/Q8KAX2 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/194439:AYT24_RS01905 ^@ http://purl.uniprot.org/uniprot/Q8KFD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity). http://togogenome.org/gene/194439:AYT24_RS08940 ^@ http://purl.uniprot.org/uniprot/Q8KB21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/194439:AYT24_RS03010 ^@ http://purl.uniprot.org/uniprot/Q8KEP2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/194439:AYT24_RS00260 ^@ http://purl.uniprot.org/uniprot/Q8KGB6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS00095 ^@ http://purl.uniprot.org/uniprot/Q8KGF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/194439:AYT24_RS01050 ^@ http://purl.uniprot.org/uniprot/Q8KFW5 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/194439:AYT24_RS09945 ^@ http://purl.uniprot.org/uniprot/Q8KAH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/194439:AYT24_RS07380 ^@ http://purl.uniprot.org/uniprot/Q8KBZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/194439:AYT24_RS03820 ^@ http://purl.uniprot.org/uniprot/Q8KE75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/194439:AYT24_RS03705 ^@ http://purl.uniprot.org/uniprot/Q8KE97 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/194439:AYT24_RS03980 ^@ http://purl.uniprot.org/uniprot/Q8KE36 ^@ Similarity ^@ Belongs to the DsrF/TusC family. http://togogenome.org/gene/194439:AYT24_RS08965 ^@ http://purl.uniprot.org/uniprot/Q8KB15 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/194439:AYT24_RS06415 ^@ http://purl.uniprot.org/uniprot/O68992 ^@ Function|||Similarity ^@ Belongs to the dUTPase family.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/194439:AYT24_RS10105 ^@ http://purl.uniprot.org/uniprot/Q8KAD1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS06800 ^@ http://purl.uniprot.org/uniprot/Q8KCC0 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/194439:AYT24_RS01510 ^@ http://purl.uniprot.org/uniprot/Q8KFM1 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/194439:AYT24_RS09775 ^@ http://purl.uniprot.org/uniprot/Q8KAK2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS06865 ^@ http://purl.uniprot.org/uniprot/Q8KCA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/194439:AYT24_RS06495 ^@ http://purl.uniprot.org/uniprot/Q8KCI5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/194439:AYT24_RS09595 ^@ http://purl.uniprot.org/uniprot/Q8KAN2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/194439:AYT24_RS07405 ^@ http://purl.uniprot.org/uniprot/Q8KBZ2 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/194439:AYT24_RS02290 ^@ http://purl.uniprot.org/uniprot/Q8KF58 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/194439:AYT24_RS01165 ^@ http://purl.uniprot.org/uniprot/Q8KFT6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS04905 ^@ http://purl.uniprot.org/uniprot/Q8KDI0 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.|||Belongs to the RecD family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/194439:AYT24_RS05565 ^@ http://purl.uniprot.org/uniprot/Q8KD25 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/194439:AYT24_RS05120 ^@ http://purl.uniprot.org/uniprot/Q8KDC3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/194439:AYT24_RS07130 ^@ http://purl.uniprot.org/uniprot/Q8KC49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/194439:AYT24_RS09410 ^@ http://purl.uniprot.org/uniprot/Q8KAS0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/194439:AYT24_RS08385 ^@ http://purl.uniprot.org/uniprot/Q8KBD5 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/194439:AYT24_RS09895 ^@ http://purl.uniprot.org/uniprot/Q8KAI0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/194439:AYT24_RS02460 ^@ http://purl.uniprot.org/uniprot/Q8KF11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/194439:AYT24_RS08160 ^@ http://purl.uniprot.org/uniprot/Q8KBI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS09140 ^@ http://purl.uniprot.org/uniprot/P58025 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Functions as an electron acceptor for pyruvate ferredoxin oxidoreductase (PFOR).|||Monomer. http://togogenome.org/gene/194439:AYT24_RS06905 ^@ http://purl.uniprot.org/uniprot/Q8KC97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS05055 ^@ http://purl.uniprot.org/uniprot/Q8KDE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS03450 ^@ http://purl.uniprot.org/uniprot/Q8KEF2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/194439:AYT24_RS08685 ^@ http://purl.uniprot.org/uniprot/Q8KB67 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/194439:AYT24_RS06170 ^@ http://purl.uniprot.org/uniprot/Q8KCQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/194439:AYT24_RS00515 ^@ http://purl.uniprot.org/uniprot/Q8KG62 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/194439:AYT24_RS09370 ^@ http://purl.uniprot.org/uniprot/Q8KAS8 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/194439:AYT24_RS02100 ^@ http://purl.uniprot.org/uniprot/Q8KF93 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/194439:AYT24_RS06195 ^@ http://purl.uniprot.org/uniprot/Q8KCP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS09015 ^@ http://purl.uniprot.org/uniprot/Q8KB03 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/194439:AYT24_RS01140 ^@ http://purl.uniprot.org/uniprot/Q8KFU4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/194439:AYT24_RS02535 ^@ http://purl.uniprot.org/uniprot/Q8KEZ2 ^@ Similarity ^@ Belongs to the AdoMet synthetase 2 family. http://togogenome.org/gene/194439:AYT24_RS01645 ^@ http://purl.uniprot.org/uniprot/Q8KFJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/194439:AYT24_RS06175 ^@ http://purl.uniprot.org/uniprot/Q8KCQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/194439:AYT24_RS00055 ^@ http://purl.uniprot.org/uniprot/Q8KGF7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/194439:AYT24_RS05385 ^@ http://purl.uniprot.org/uniprot/Q8KD66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS07595 ^@ http://purl.uniprot.org/uniprot/Q8KBU9 ^@ Similarity ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. http://togogenome.org/gene/194439:AYT24_RS06740 ^@ http://purl.uniprot.org/uniprot/Q8KCD0 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/194439:AYT24_RS07395 ^@ http://purl.uniprot.org/uniprot/Q9F719 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS06590 ^@ http://purl.uniprot.org/uniprot/Q8KCG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00380 ^@ http://purl.uniprot.org/uniprot/Q8KG91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS03640 ^@ http://purl.uniprot.org/uniprot/Q8KEB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS06270 ^@ http://purl.uniprot.org/uniprot/Q8KCN1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/194439:AYT24_RS09555 ^@ http://purl.uniprot.org/uniprot/Q8KAP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/194439:AYT24_RS01810 ^@ http://purl.uniprot.org/uniprot/Q8KFF6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/194439:AYT24_RS07045 ^@ http://purl.uniprot.org/uniprot/Q8KC68 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/194439:AYT24_RS03490 ^@ http://purl.uniprot.org/uniprot/Q8KEE3 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/194439:AYT24_RS08225 ^@ http://purl.uniprot.org/uniprot/Q8KBG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS02505 ^@ http://purl.uniprot.org/uniprot/Q8KF00 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/194439:AYT24_RS03500 ^@ http://purl.uniprot.org/uniprot/Q8KEE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS05410 ^@ http://purl.uniprot.org/uniprot/Q8KD61 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/194439:AYT24_RS04900 ^@ http://purl.uniprot.org/uniprot/Q8KDI1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/194439:AYT24_RS03650 ^@ http://purl.uniprot.org/uniprot/Q8KEB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS00195 ^@ http://purl.uniprot.org/uniprot/Q8KGC9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS09345 ^@ http://purl.uniprot.org/uniprot/Q8KAT5 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/194439:AYT24_RS02885 ^@ http://purl.uniprot.org/uniprot/Q8KER7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. http://togogenome.org/gene/194439:AYT24_RS03935 ^@ http://purl.uniprot.org/uniprot/Q8KE48 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06080 ^@ http://purl.uniprot.org/uniprot/Q8KCS2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/194439:AYT24_RS04485 ^@ http://purl.uniprot.org/uniprot/Q8KDS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/194439:AYT24_RS09080 ^@ http://purl.uniprot.org/uniprot/Q8KAY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GmhB family.|||Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS07995 ^@ http://purl.uniprot.org/uniprot/Q8KBL5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/194439:AYT24_RS08565 ^@ http://purl.uniprot.org/uniprot/Q8KB95 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/194439:AYT24_RS08290 ^@ http://purl.uniprot.org/uniprot/Q8KBF5 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/194439:AYT24_RS06000 ^@ http://purl.uniprot.org/uniprot/Q8KCT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/194439:AYT24_RS09030 ^@ http://purl.uniprot.org/uniprot/Q8KAZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS10150 ^@ http://purl.uniprot.org/uniprot/Q8KAC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/194439:AYT24_RS01420 ^@ http://purl.uniprot.org/uniprot/Q8KFN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS07305 ^@ http://purl.uniprot.org/uniprot/Q8KC14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/194439:AYT24_RS01020 ^@ http://purl.uniprot.org/uniprot/Q8KFX1 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/194439:AYT24_RS01330 ^@ http://purl.uniprot.org/uniprot/Q8KFQ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS01200 ^@ http://purl.uniprot.org/uniprot/Q8KFS9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/194439:AYT24_RS10345 ^@ http://purl.uniprot.org/uniprot/Q8KA87 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent (By similarity).|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).|||The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).|||This protein is much smaller than the orthologs present in other bacteria; the NBD2 and C-terminal domains are missing. However, there is a paralog in the genome (clpB1) that encodes a protein which contains only the NBD2 and C-terminal domains. http://togogenome.org/gene/194439:AYT24_RS09050 ^@ http://purl.uniprot.org/uniprot/Q8KAZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/194439:AYT24_RS01900 ^@ http://purl.uniprot.org/uniprot/Q8KFD7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/194439:AYT24_RS05265 ^@ http://purl.uniprot.org/uniprot/Q8KD91 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/194439:AYT24_RS00255 ^@ http://purl.uniprot.org/uniprot/Q8KGB7 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/194439:AYT24_RS00505 ^@ http://purl.uniprot.org/uniprot/Q8KG64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS03600 ^@ http://purl.uniprot.org/uniprot/Q8KEC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS07810 ^@ http://purl.uniprot.org/uniprot/Q8KBQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00790 ^@ http://purl.uniprot.org/uniprot/Q8KG14 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/194439:AYT24_RS03665 ^@ http://purl.uniprot.org/uniprot/Q8KEA7 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/194439:AYT24_RS02035 ^@ http://purl.uniprot.org/uniprot/Q8KFA7 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/194439:AYT24_RS08200 ^@ http://purl.uniprot.org/uniprot/Q8KBH3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/194439:AYT24_RS01235 ^@ http://purl.uniprot.org/uniprot/Q8KFS2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/194439:AYT24_RS01730 ^@ http://purl.uniprot.org/uniprot/Q8KFH5 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/194439:AYT24_RS08135 ^@ http://purl.uniprot.org/uniprot/Q8KBI7 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/194439:AYT24_RS09200 ^@ http://purl.uniprot.org/uniprot/Q8KAW4 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/194439:AYT24_RS06320 ^@ http://purl.uniprot.org/uniprot/Q8KCL8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/194439:AYT24_RS00715 ^@ http://purl.uniprot.org/uniprot/Q8KG25 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/194439:AYT24_RS04145 ^@ http://purl.uniprot.org/uniprot/Q8KDZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.|||Cell inner membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/194439:AYT24_RS07280 ^@ http://purl.uniprot.org/uniprot/Q93SU8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/194439:AYT24_RS07310 ^@ http://purl.uniprot.org/uniprot/Q8KC12 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/194439:AYT24_RS00440 ^@ http://purl.uniprot.org/uniprot/Q8KG79 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent (By similarity).|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).|||The N-terminal domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).|||This protein is much smaller than the orthologs present in other bacteria; the N-terminal and NBD1 domains are missing. However, there is a paralog in the genome (clpB2) that encodes a protein which contains only the N-terminal and NBD1 domains. http://togogenome.org/gene/194439:AYT24_RS09950 ^@ http://purl.uniprot.org/uniprot/Q8KAG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS08000 ^@ http://purl.uniprot.org/uniprot/Q8KBL4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Although strongly related to RuBisCO family, it lacks the conserved Lys active site in position 327, which is replaced by an Arg residue, suggesting that it may catalyze enolization but not carboxylation.|||Belongs to the RuBisCO large chain family. Type IV subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||May be involved in sulfur metabolism and oxidative stress response. Does not show RuBisCO activity. http://togogenome.org/gene/194439:AYT24_RS01855 ^@ http://purl.uniprot.org/uniprot/Q8KFE6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS06970 ^@ http://purl.uniprot.org/uniprot/Q8KC83 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS09225 ^@ http://purl.uniprot.org/uniprot/Q8KAV9 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/194439:AYT24_RS01290 ^@ http://purl.uniprot.org/uniprot/Q8KFR1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/194439:AYT24_RS06360 ^@ http://purl.uniprot.org/uniprot/Q8KCK9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS03730 ^@ http://purl.uniprot.org/uniprot/Q8KE91 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/194439:AYT24_RS03620 ^@ http://purl.uniprot.org/uniprot/Q8KEB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/194439:AYT24_RS07440 ^@ http://purl.uniprot.org/uniprot/Q8KBY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/194439:AYT24_RS10065 ^@ http://purl.uniprot.org/uniprot/Q8KAE1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/194439:AYT24_RS05655 ^@ http://purl.uniprot.org/uniprot/Q8KD07 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/194439:AYT24_RS00900 ^@ http://purl.uniprot.org/uniprot/Q8KFZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS00620 ^@ http://purl.uniprot.org/uniprot/Q8KG38 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/194439:AYT24_RS09235 ^@ http://purl.uniprot.org/uniprot/Q8KAV6 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/194439:AYT24_RS05040 ^@ http://purl.uniprot.org/uniprot/Q8KDE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/194439:AYT24_RS07480 ^@ http://purl.uniprot.org/uniprot/Q8KBX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX (PubMed:23651039). Can bind the benzodiazepine receptor agonist PK-11195 (in vitro); this interferes with photooxidative tetrapyrrole degradation (PubMed:23651039). May play a role in the transmembrane transport of tetrapyrroles and similar compounds (By similarity).|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS08210 ^@ http://purl.uniprot.org/uniprot/Q8KBH1 ^@ Function|||Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/194439:AYT24_RS04415 ^@ http://purl.uniprot.org/uniprot/Q8KDT4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/194439:AYT24_RS01525 ^@ http://purl.uniprot.org/uniprot/Q8KFL8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/194439:AYT24_RS06980 ^@ http://purl.uniprot.org/uniprot/Q8KC81 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/194439:AYT24_RS07360 ^@ http://purl.uniprot.org/uniprot/Q8KBZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/194439:AYT24_RS09145 ^@ http://purl.uniprot.org/uniprot/Q8KAX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/194439:AYT24_RS02690 ^@ http://purl.uniprot.org/uniprot/Q8KEW2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/194439:AYT24_RS10170 ^@ http://purl.uniprot.org/uniprot/Q8KAB9 ^@ Subcellular Location Annotation ^@ Membrane