http://togogenome.org/gene/2041044:CPZ25_RS14455 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7V7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/2041044:CPZ25_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A2A5TIU4 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8I9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC87 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9L6 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2041044:CPZ25_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A4P9C874 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A4P9C959 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS14415 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCL6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3F2 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2041044:CPZ25_RS16725 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDG1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/2041044:CPZ25_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A4P9C740 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2041044:CPZ25_RS14915 ^@ http://purl.uniprot.org/uniprot/A0A2A5TIU4 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM70 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2041044:CPZ25_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBW3 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS19110 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/2041044:CPZ25_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/2041044:CPZ25_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/2041044:CPZ25_RS13285 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9M1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7I2 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/2041044:CPZ25_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS16335 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD53 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of alpha-methyl-L-serine to D-alanine with tetrahydrofolate (THF) serving as the one-carbon carrier.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5W8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/2041044:CPZ25_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A4P9C681 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/2041044:CPZ25_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6W5 ^@ Function ^@ Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. http://togogenome.org/gene/2041044:CPZ25_RS08100 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7A2 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/2041044:CPZ25_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5X0 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/2041044:CPZ25_RS16150 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB23 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/2041044:CPZ25_RS16660 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB98 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/2041044:CPZ25_RS13115 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBN3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/2041044:CPZ25_RS14645 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM98 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8H7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2041044:CPZ25_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6X3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/2041044:CPZ25_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF67 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/2041044:CPZ25_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9G9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/2041044:CPZ25_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDI5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/2041044:CPZ25_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5J5 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/2041044:CPZ25_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A4P9C867 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/2041044:CPZ25_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/2041044:CPZ25_RS11845 ^@ http://purl.uniprot.org/uniprot/A0A4P9C900 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/2041044:CPZ25_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/2041044:CPZ25_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8J4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2041044:CPZ25_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA57 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2041044:CPZ25_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2041044:CPZ25_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Y5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2041044:CPZ25_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9W4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2041044:CPZ25_RS18830 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/2041044:CPZ25_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/2041044:CPZ25_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA59 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A4P9C968 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS20105 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF02 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/2041044:CPZ25_RS16280 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB62 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A4P9C888 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/2041044:CPZ25_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6U5 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2041044:CPZ25_RS15200 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/2041044:CPZ25_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A4P9C745 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. http://togogenome.org/gene/2041044:CPZ25_RS14430 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCB3 ^@ Function ^@ Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. http://togogenome.org/gene/2041044:CPZ25_RS10650 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAD1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4C3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/2041044:CPZ25_RS14485 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCC3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/2041044:CPZ25_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Y7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/2041044:CPZ25_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8G1 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/2041044:CPZ25_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE48 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2041044:CPZ25_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7T1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2041044:CPZ25_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6C1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2041044:CPZ25_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBU7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of alpha-methyl-L-serine to D-alanine with tetrahydrofolate (THF) serving as the one-carbon carrier.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS15655 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS19185 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCF9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A4P9C982 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS15220 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAY8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/2041044:CPZ25_RS10315 ^@ http://purl.uniprot.org/uniprot/A0A4P9C836 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A4P9C799 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/2041044:CPZ25_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC21 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA63 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/2041044:CPZ25_RS15825 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM68 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/2041044:CPZ25_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A4P9C676 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/2041044:CPZ25_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLW5 ^@ Similarity|||Subunit ^@ Belongs to the RNase H family.|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS16690 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBD3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS10385 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9N0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM62 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS11795 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/2041044:CPZ25_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6Z2 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6E9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/2041044:CPZ25_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A4P9C804 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/2041044:CPZ25_RS17460 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDN8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/2041044:CPZ25_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCH8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS12880 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9A3 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/2041044:CPZ25_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7A6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A2A5TGF1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/2041044:CPZ25_RS20000 ^@ http://purl.uniprot.org/uniprot/A0A4P9CFG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/2041044:CPZ25_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2041044:CPZ25_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7N5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A4P9C854 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/2041044:CPZ25_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A4P9C821 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/2041044:CPZ25_RS18840 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCK5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/2041044:CPZ25_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBM0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/2041044:CPZ25_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6S4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/2041044:CPZ25_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A4P9C616 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS10320 ^@ http://purl.uniprot.org/uniprot/A0A4P9C870 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2041044:CPZ25_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLH6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS12890 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9F1 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/2041044:CPZ25_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD70 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS16340 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6K9 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/2041044:CPZ25_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9Q8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7Q3 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/2041044:CPZ25_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7G9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2041044:CPZ25_RS19865 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCT2 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/2041044:CPZ25_RS08350 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7K3 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/2041044:CPZ25_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A4P9C742 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/2041044:CPZ25_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A4P9C724 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAI6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/2041044:CPZ25_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4G3 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/2041044:CPZ25_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9D2 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/2041044:CPZ25_RS16770 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/2041044:CPZ25_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7B1 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/2041044:CPZ25_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Y5 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/2041044:CPZ25_RS13360 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA31 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9J9 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3Q0 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS17085 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/2041044:CPZ25_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8X6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/2041044:CPZ25_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBG7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS18355 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18825 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC75 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/2041044:CPZ25_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6T3 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/2041044:CPZ25_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCK7 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/2041044:CPZ25_RS09775 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA28 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/2041044:CPZ25_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C6 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/2041044:CPZ25_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A4P9C873 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/2041044:CPZ25_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3D2 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/2041044:CPZ25_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/2041044:CPZ25_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A4P9C879 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2041044:CPZ25_RS13220 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17425 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBN4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/2041044:CPZ25_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3K5 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS19120 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMI1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/2041044:CPZ25_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A4P9C536 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease N1/T1 family.|||Secreted http://togogenome.org/gene/2041044:CPZ25_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A4P9C426 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD99 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2041044:CPZ25_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3X2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/2041044:CPZ25_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A2A5T9X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2041044:CPZ25_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM14 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18510 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC54 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/2041044:CPZ25_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA69 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2041044:CPZ25_RS18885 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEG4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/2041044:CPZ25_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4V6 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/2041044:CPZ25_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7B6 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/2041044:CPZ25_RS19530 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCW9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS19205 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCR6 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2041044:CPZ25_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5P5 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/2041044:CPZ25_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7B2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS14420 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAJ9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/2041044:CPZ25_RS16310 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB28 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/2041044:CPZ25_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA82 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2041044:CPZ25_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A2A5T8I2 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM67 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2041044:CPZ25_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8A3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2041044:CPZ25_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEY0 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/2041044:CPZ25_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6M1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/2041044:CPZ25_RS20010 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCU9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2041044:CPZ25_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4S7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/2041044:CPZ25_RS16425 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDT7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLZ1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2041044:CPZ25_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A2A5T9U2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/2041044:CPZ25_RS14285 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3W8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/2041044:CPZ25_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8K3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A4V1GME4 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A4P9C778 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/2041044:CPZ25_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A4P9C716 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A4P9C861 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A4P9C396 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A2A5TAF5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/2041044:CPZ25_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5S3 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2041044:CPZ25_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8B3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA95 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2041044:CPZ25_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7V0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/2041044:CPZ25_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/2041044:CPZ25_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2041044:CPZ25_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A4P9C847 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS15715 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAX1 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/2041044:CPZ25_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2041044:CPZ25_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAY5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/2041044:CPZ25_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3Q8 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/2041044:CPZ25_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBQ0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/2041044:CPZ25_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3X5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A4P9C700 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBJ1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2041044:CPZ25_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBW8 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/2041044:CPZ25_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A2A5TCM8 ^@ Function|||Similarity ^@ Belongs to the desulfoferrodoxin family.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity. http://togogenome.org/gene/2041044:CPZ25_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEZ6 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/2041044:CPZ25_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS16635 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBC2 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/2041044:CPZ25_RS13055 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9Y2 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/2041044:CPZ25_RS19855 ^@ http://purl.uniprot.org/uniprot/A0A4P9CFF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/2041044:CPZ25_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A4V1GME9 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18180 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDZ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2041044:CPZ25_RS13345 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9M0 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBT4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A4P9C690 ^@ Cofactor ^@ Binds 1 Mn(2+) or Fe(2+) ion per subunit. http://togogenome.org/gene/2041044:CPZ25_RS11015 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A4P9C951 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A2A5T8D7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA11 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/2041044:CPZ25_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A4P9C558 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/2041044:CPZ25_RS15080 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAJ7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2041044:CPZ25_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A4P9C649 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS19420 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF84 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A4P9C721 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/2041044:CPZ25_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8K0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/2041044:CPZ25_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2041044:CPZ25_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8X4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/2041044:CPZ25_RS17885 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/2041044:CPZ25_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBH7 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE68 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS19255 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF56 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/2041044:CPZ25_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB84 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/2041044:CPZ25_RS18665 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCC4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBM4 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9X5 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2041044:CPZ25_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A4P9C694 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/2041044:CPZ25_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4J1 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/2041044:CPZ25_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2041044:CPZ25_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2041044:CPZ25_RS19705 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCU0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS11920 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Y5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6A0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6D6 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits. http://togogenome.org/gene/2041044:CPZ25_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8M9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2041044:CPZ25_RS19920 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/2041044:CPZ25_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A4P9C855 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLN5 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/2041044:CPZ25_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEG8 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/2041044:CPZ25_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS19045 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEJ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS16305 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB49 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLJ1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Q6 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9H6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4T6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A4P9C552 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2041044:CPZ25_RS19145 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEL0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/2041044:CPZ25_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC67 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A4P9C453 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9R2 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2041044:CPZ25_RS18870 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCA9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2041044:CPZ25_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2041044:CPZ25_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8D6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/2041044:CPZ25_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA39 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS14615 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAA3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAD9 ^@ Function ^@ General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/2041044:CPZ25_RS20185 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD14 ^@ Function|||Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. Butyryl-CoA CoA-transferase subfamily.|||Coenzyme A-transferase that converts butyryl-CoA to butyrate. http://togogenome.org/gene/2041044:CPZ25_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/2041044:CPZ25_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/2041044:CPZ25_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA28 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/2041044:CPZ25_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAQ6 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/2041044:CPZ25_RS11835 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB19 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG69 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS14120 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA56 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS13025 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9I0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/2041044:CPZ25_RS16775 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2041044:CPZ25_RS18630 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC45 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2041044:CPZ25_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3J9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/2041044:CPZ25_RS17450 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBQ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/2041044:CPZ25_RS16975 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A4P9C564 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2041044:CPZ25_RS18635 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/2041044:CPZ25_RS19190 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCD3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS18335 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC26 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/2041044:CPZ25_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLW1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/2041044:CPZ25_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A4P9C602 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/2041044:CPZ25_RS17040 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDH4 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/2041044:CPZ25_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLI0 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/2041044:CPZ25_RS16570 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDD1 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/2041044:CPZ25_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A4P9C715 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/2041044:CPZ25_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLH9 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Q1 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/2041044:CPZ25_RS08900 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/2041044:CPZ25_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A4P9C449 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2041044:CPZ25_RS09580 ^@ http://purl.uniprot.org/uniprot/A0A2A5T8F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS10335 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAI4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2041044:CPZ25_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAZ1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17760 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6A9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2041044:CPZ25_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A4P9C473 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/2041044:CPZ25_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5W5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2041044:CPZ25_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8B4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2041044:CPZ25_RS18920 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2041044:CPZ25_RS13295 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9L0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2041044:CPZ25_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM83 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/2041044:CPZ25_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9M3 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/2041044:CPZ25_RS16745 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A4P9C637 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG58 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/2041044:CPZ25_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4A7 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/2041044:CPZ25_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2041044:CPZ25_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A2A5T8L3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Q8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS18270 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7C4 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2041044:CPZ25_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4P6 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/2041044:CPZ25_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A4P9CFT2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA80 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A4P9C941 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4K1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS18965 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC77 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/2041044:CPZ25_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9D4 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS17670 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBP9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/2041044:CPZ25_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7J1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/2041044:CPZ25_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A4P9C529 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/2041044:CPZ25_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM10 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2041044:CPZ25_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/2041044:CPZ25_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9B7 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/2041044:CPZ25_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/2041044:CPZ25_RS18310 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBZ3 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/2041044:CPZ25_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9C1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2041044:CPZ25_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A2A5TGZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2041044:CPZ25_RS09170 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9L8 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6T4 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2041044:CPZ25_RS20030 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/2041044:CPZ25_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A4P9C664 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/2041044:CPZ25_RS16675 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/2041044:CPZ25_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBL2 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/2041044:CPZ25_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6J2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2041044:CPZ25_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A4P9C647 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2041044:CPZ25_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLX3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS12030 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9B8 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/2041044:CPZ25_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A2A5TAB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2041044:CPZ25_RS08420 ^@ http://purl.uniprot.org/uniprot/A0A4P9C777 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/2041044:CPZ25_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5J3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS13125 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9I8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpB RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpA.|||Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H). http://togogenome.org/gene/2041044:CPZ25_RS18315 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8U8 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/2041044:CPZ25_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A4P9C768 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS17790 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBR0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/2041044:CPZ25_RS20060 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/2041044:CPZ25_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBP1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS14160 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2041044:CPZ25_RS21005 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8G4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/2041044:CPZ25_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9H1 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/2041044:CPZ25_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBH8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6E1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane|||Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents. http://togogenome.org/gene/2041044:CPZ25_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6U2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/2041044:CPZ25_RS16835 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE13 ^@ Similarity ^@ Belongs to the sigma-70 factor family. http://togogenome.org/gene/2041044:CPZ25_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6I2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3I1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A4P9C992 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/2041044:CPZ25_RS04840 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/2041044:CPZ25_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6G9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/2041044:CPZ25_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBL6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2041044:CPZ25_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3H0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Z4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/2041044:CPZ25_RS12380 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9M2 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/2041044:CPZ25_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/2041044:CPZ25_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7E3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2041044:CPZ25_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3M2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/2041044:CPZ25_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A4P9C817 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/2041044:CPZ25_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8B0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2041044:CPZ25_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6K1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/2041044:CPZ25_RS13215 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8D8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A2A5T8C3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/2041044:CPZ25_RS08590 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7A5 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/2041044:CPZ25_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8D9 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/2041044:CPZ25_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3S2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/2041044:CPZ25_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBA1 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2041044:CPZ25_RS09860 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS13470 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBV1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4I3 ^@ Function ^@ Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes. http://togogenome.org/gene/2041044:CPZ25_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLW8 ^@ Similarity ^@ Belongs to the CpsD/CapB family. http://togogenome.org/gene/2041044:CPZ25_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer. http://togogenome.org/gene/2041044:CPZ25_RS12120 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCV5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS15320 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDA5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/2041044:CPZ25_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAR5 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/2041044:CPZ25_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A4P9C954 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2041044:CPZ25_RS19100 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF31 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A4P9C774 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/2041044:CPZ25_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/2041044:CPZ25_RS18925 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCG0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2041044:CPZ25_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8J3 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/2041044:CPZ25_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS20090 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA72 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2041044:CPZ25_RS14090 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAJ8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7H3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2041044:CPZ25_RS18655 ^@ http://purl.uniprot.org/uniprot/A0A4P9CED3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2041044:CPZ25_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A4P9C686 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCM2 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/2041044:CPZ25_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6B0 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/2041044:CPZ25_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS15945 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB09 ^@ Similarity ^@ Belongs to the plasmid mobilization pre family. http://togogenome.org/gene/2041044:CPZ25_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBC1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8N3 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Q9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/2041044:CPZ25_RS20120 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCW8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6Q2 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/2041044:CPZ25_RS19585 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCP1 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/2041044:CPZ25_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAI7 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A4P9C999 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/2041044:CPZ25_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3L0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDR9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS17810 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBU6 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAI0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/2041044:CPZ25_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA77 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS11895 ^@ http://purl.uniprot.org/uniprot/A0A4P9C909 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/2041044:CPZ25_RS16285 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD46 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS11915 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB03 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/2041044:CPZ25_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLW7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A4P9C566 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS14185 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCH6 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/2041044:CPZ25_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLN2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2041044:CPZ25_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Q2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/2041044:CPZ25_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A4P9C841 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10220 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/2041044:CPZ25_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS14345 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA83 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/2041044:CPZ25_RS15090 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAK9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG16 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/2041044:CPZ25_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A4P9C975 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Q2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2041044:CPZ25_RS20020 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMJ7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE18 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/2041044:CPZ25_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2041044:CPZ25_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEK1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS18285 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE08 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/2041044:CPZ25_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBC8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS19195 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEL9 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/2041044:CPZ25_RS16295 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/2041044:CPZ25_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A4P9C782 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/2041044:CPZ25_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS15075 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMA6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2041044:CPZ25_RS17700 ^@ http://purl.uniprot.org/uniprot/A0A4P9CED9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4W3 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/2041044:CPZ25_RS12585 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5T3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/2041044:CPZ25_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7J8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4R4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/2041044:CPZ25_RS15165 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAY1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/2041044:CPZ25_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBZ6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS19870 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/2041044:CPZ25_RS14635 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAE8 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2041044:CPZ25_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A4P9C753 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA09 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/2041044:CPZ25_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5M1 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/2041044:CPZ25_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAK0 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCB7 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/2041044:CPZ25_RS15515 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAR3 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/2041044:CPZ25_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA81 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/2041044:CPZ25_RS18650 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/2041044:CPZ25_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBN8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/2041044:CPZ25_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A4P9C807 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/2041044:CPZ25_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2041044:CPZ25_RS19180 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A4P9C413 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/2041044:CPZ25_RS18955 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2041044:CPZ25_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8G9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/2041044:CPZ25_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM23 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7E6 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/2041044:CPZ25_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4M6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/2041044:CPZ25_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBA5 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS12440 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A4P9C452 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/2041044:CPZ25_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A4P9C464 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS19330 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A4P9C512 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2041044:CPZ25_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAG8 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM79 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18775 ^@ http://purl.uniprot.org/uniprot/A0A4P9CC69 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/2041044:CPZ25_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCF7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/2041044:CPZ25_RS19695 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMJ2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBL7 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/2041044:CPZ25_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM17 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2041044:CPZ25_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A4P9C827 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8K9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBB6 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/2041044:CPZ25_RS11020 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2041044:CPZ25_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9R3 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS16605 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB86 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/2041044:CPZ25_RS17435 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDU6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/2041044:CPZ25_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA75 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/2041044:CPZ25_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAZ5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/2041044:CPZ25_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2041044:CPZ25_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/2041044:CPZ25_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD69 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/2041044:CPZ25_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3V9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS18075 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMG1 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/2041044:CPZ25_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A4P9C7E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/2041044:CPZ25_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5S2 ^@ Similarity ^@ Belongs to the KdgT transporter family. http://togogenome.org/gene/2041044:CPZ25_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2041044:CPZ25_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5U6 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/2041044:CPZ25_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAI2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A4P9CD88 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/2041044:CPZ25_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8I4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2041044:CPZ25_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A4P9C887 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A4P9C672 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/2041044:CPZ25_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4Q5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM86 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/2041044:CPZ25_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/2041044:CPZ25_RS13300 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9M8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A2A5T9Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/2041044:CPZ25_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS18835 ^@ http://purl.uniprot.org/uniprot/A0A4P9CEY8 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/2041044:CPZ25_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A4P9C643 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS15110 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAX2 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/2041044:CPZ25_RS18440 ^@ http://purl.uniprot.org/uniprot/A0A4P9CE35 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/2041044:CPZ25_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A4P9C5X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2041044:CPZ25_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4B8 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/2041044:CPZ25_RS16510 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB88 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/2041044:CPZ25_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCY1 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/2041044:CPZ25_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2041044:CPZ25_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A2A5TG81 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/2041044:CPZ25_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9U5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2041044:CPZ25_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9L7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/2041044:CPZ25_RS13350 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBR2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS19640 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A4P9C438 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/2041044:CPZ25_RS03350 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4R3 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/2041044:CPZ25_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAB9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2041044:CPZ25_RS18660 ^@ http://purl.uniprot.org/uniprot/A0A4V1GMH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2041044:CPZ25_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A4P9C3I0 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/2041044:CPZ25_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/2041044:CPZ25_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8P5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS11930 ^@ http://purl.uniprot.org/uniprot/A0A4P9C985 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/2041044:CPZ25_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9U6 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/2041044:CPZ25_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLM6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A4P9C725 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS13945 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9Y0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAA2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2041044:CPZ25_RS19140 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2041044:CPZ25_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A4P9CAS1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2041044:CPZ25_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A4P9C469 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS17830 ^@ http://purl.uniprot.org/uniprot/A0A4P9CBS6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/2041044:CPZ25_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Q0 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/2041044:CPZ25_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A2A5TA19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS11950 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/2041044:CPZ25_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2041044:CPZ25_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8L2 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/2041044:CPZ25_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A2A5TGZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2041044:CPZ25_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A4P9C691 ^@ Function ^@ May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/2041044:CPZ25_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A4P9CF48 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/2041044:CPZ25_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A4V1GLN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8R9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS18645 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCG9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2041044:CPZ25_RS20055 ^@ http://purl.uniprot.org/uniprot/A0A4P9CFH9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/2041044:CPZ25_RS14495 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA96 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS08880 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS14095 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A4P9CB78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A4P9C4P4 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/2041044:CPZ25_RS14490 ^@ http://purl.uniprot.org/uniprot/A0A4V1GM95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2041044:CPZ25_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A2A5TGI7 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2041044:CPZ25_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A4P9C9N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2041044:CPZ25_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8H2 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/2041044:CPZ25_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A4P9C8Q7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2041044:CPZ25_RS13905 ^@ http://purl.uniprot.org/uniprot/A0A4P9CA21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/2041044:CPZ25_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A4P9CDW7 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/2041044:CPZ25_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/2041044:CPZ25_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6J6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2041044:CPZ25_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A4P9C979 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2041044:CPZ25_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A4P9C6C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2041044:CPZ25_RS19085 ^@ http://purl.uniprot.org/uniprot/A0A4P9CCE3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA.