http://togogenome.org/gene/243161:TC_RS02720 ^@ http://purl.uniprot.org/uniprot/Q9PKC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03140 ^@ http://purl.uniprot.org/uniprot/Q9PK53 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/243161:TC_RS04305 ^@ http://purl.uniprot.org/uniprot/Q9PJI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YscJ lipoprotein family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/243161:TC_RS03855 ^@ http://purl.uniprot.org/uniprot/Q9PJS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/243161:TC_RS00270 ^@ http://purl.uniprot.org/uniprot/P71146 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS04360 ^@ http://purl.uniprot.org/uniprot/Q9PJH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/243161:TC_RS01710 ^@ http://purl.uniprot.org/uniprot/Q9PKX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 9 family.|||Monomer.|||Part of the ATP-binding cassette (ABC) transport system YtgABCD involved in metal import. Binds Fe(2+), Mn(2+) and Ni(2+), with a preference for Fe(2+) and delivers them to the membrane permease for translocation into the cytoplasm.|||Periplasm http://togogenome.org/gene/243161:TC_RS04090 ^@ http://purl.uniprot.org/uniprot/Q9PJM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/243161:TC_RS01850 ^@ http://purl.uniprot.org/uniprot/Q9PKU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). http://togogenome.org/gene/243161:TC_RS03430 ^@ http://purl.uniprot.org/uniprot/P56836 ^@ Function|||Induction|||Miscellaneous|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock (By similarity).|||Expressed early during infection. http://togogenome.org/gene/243161:TC_RS01690 ^@ http://purl.uniprot.org/uniprot/Q9PKX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01250 ^@ http://purl.uniprot.org/uniprot/Q9PL60 ^@ Similarity ^@ Belongs to the chlamydial CPn_1016/CT_858/TC_0248 family. http://togogenome.org/gene/243161:TC_RS04035 ^@ http://purl.uniprot.org/uniprot/Q9PJN4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/243161:TC_RS01520 ^@ http://purl.uniprot.org/uniprot/Q9PL06 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/243161:TC_RS02895 ^@ http://purl.uniprot.org/uniprot/Q9PK95 ^@ Caution|||Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||This sequence may not function as a hydroxymethylbilane synthase because it lacks the cysteine residue necessary for attachment of the dipyrromethane cofactor. http://togogenome.org/gene/243161:TC_RS02970 ^@ http://purl.uniprot.org/uniprot/Q9PK80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/243161:TC_RS03750 ^@ http://purl.uniprot.org/uniprot/Q9PJT6 ^@ Similarity ^@ Belongs to the chlamydial CPn_0572/CT_456/TC_0741 family. http://togogenome.org/gene/243161:TC_RS01370 ^@ http://purl.uniprot.org/uniprot/Q9PL37 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/243161:TC_RS00010 ^@ http://purl.uniprot.org/uniprot/Q9PLU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/243161:TC_RS02310 ^@ http://purl.uniprot.org/uniprot/Q9PKK4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/243161:TC_RS00095 ^@ http://purl.uniprot.org/uniprot/Q9PLS7 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/243161:TC_RS02625 ^@ http://purl.uniprot.org/uniprot/Q9PKE8 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/243161:TC_RS00550 ^@ http://purl.uniprot.org/uniprot/Q9PLJ4 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/243161:TC_RS03195 ^@ http://purl.uniprot.org/uniprot/Q9PK42 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/243161:TC_RS03665 ^@ http://purl.uniprot.org/uniprot/Q9PJV2 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/243161:TC_RS01825 ^@ http://purl.uniprot.org/uniprot/Q9PKU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS02360 ^@ http://purl.uniprot.org/uniprot/Q9PKJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/243161:TC_RS00810 ^@ http://purl.uniprot.org/uniprot/Q9PLF0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/243161:TC_RS01750 ^@ http://purl.uniprot.org/uniprot/Q9PKW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase. http://togogenome.org/gene/243161:TC_RS00340 ^@ http://purl.uniprot.org/uniprot/Q9PLN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Cell membrane|||Potential transporter for phosphate. http://togogenome.org/gene/243161:TC_RS01715 ^@ http://purl.uniprot.org/uniprot/Q9PKX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Part of an ATP-driven transport system TC_0338/TC_0339/TC_0341/TC_0342 for a metal. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/243161:TC_RS04070 ^@ http://purl.uniprot.org/uniprot/Q9PJM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/243161:TC_RS00100 ^@ http://purl.uniprot.org/uniprot/Q9PLS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02635 ^@ http://purl.uniprot.org/uniprot/Q9PKE6 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). http://togogenome.org/gene/243161:TC_RS03980 ^@ http://purl.uniprot.org/uniprot/Q9PJP4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/243161:TC_RS02585 ^@ http://purl.uniprot.org/uniprot/Q9PKF6 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/243161:TC_RS03700 ^@ http://purl.uniprot.org/uniprot/Q9PJU6 ^@ Similarity ^@ Belongs to the EUO family. http://togogenome.org/gene/243161:TC_RS03540 ^@ http://purl.uniprot.org/uniprot/Q9PJX8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell inner membrane|||Part of an ATP-driven transport system TC_0696/TC_0697/TC_0698 for a metal. http://togogenome.org/gene/243161:TC_RS04215 ^@ http://purl.uniprot.org/uniprot/Q9PJK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS01415 ^@ http://purl.uniprot.org/uniprot/Q9PL28 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/243161:TC_RS04230 ^@ http://purl.uniprot.org/uniprot/Q9PJJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the PolIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex (By similarity).|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity). http://togogenome.org/gene/243161:TC_RS01745 ^@ http://purl.uniprot.org/uniprot/Q9PKW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). http://togogenome.org/gene/243161:TC_RS01720 ^@ http://purl.uniprot.org/uniprot/Q9PKX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell inner membrane|||Part of an ATP-driven transport system TC_0338/TC_0339/TC_0341/TC_0342 for a metal. http://togogenome.org/gene/243161:TC_RS00460 ^@ http://purl.uniprot.org/uniprot/Q9PLL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS04045 ^@ http://purl.uniprot.org/uniprot/Q9PJN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/243161:TC_RS02805 ^@ http://purl.uniprot.org/uniprot/Q9PKB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/243161:TC_RS04050 ^@ http://purl.uniprot.org/uniprot/Q9PJN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/243161:TC_RS04000 ^@ http://purl.uniprot.org/uniprot/Q9PJP0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/243161:TC_RS03680 ^@ http://purl.uniprot.org/uniprot/Q9PJV0 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. It is present but the disulfide bonds are reduced in reticulate bodies (RBs) (By similarity).|||Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).|||Periplasm|||Was thought to be an outer membrane protein as it is part of a disulfide cross-linked complex that is insoluble in the detergent Sarkosyl; however based on experiments in C.psittaci it is likely to be periplasmic. http://togogenome.org/gene/243161:TC_RS01930 ^@ http://purl.uniprot.org/uniprot/Q9PKS6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/243161:TC_RS01585 ^@ http://purl.uniprot.org/uniprot/P38020 ^@ Developmental Stage|||Function|||Similarity ^@ Belongs to the histone H1/H5 family. HCT subfamily.|||Expressed late in chlamydial development, during the transition from reticulate bodies to elementary bodies.|||Might have a role in establishing the nucleoid structure of elementary bodies. http://togogenome.org/gene/243161:TC_RS02985 ^@ http://purl.uniprot.org/uniprot/P38001 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/243161:TC_RS04095 ^@ http://purl.uniprot.org/uniprot/Q9PJM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS03320 ^@ http://purl.uniprot.org/uniprot/Q9PK18 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/243161:TC_RS01120 ^@ http://purl.uniprot.org/uniprot/Q9PL84 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). http://togogenome.org/gene/243161:TC_RS03885 ^@ http://purl.uniprot.org/uniprot/Q9PJR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS03490 ^@ http://purl.uniprot.org/uniprot/Q9PJY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/243161:TC_RS01390 ^@ http://purl.uniprot.org/uniprot/Q9PL33 ^@ Similarity ^@ Belongs to the chlamydial CPn_0441/CT_007/TC_0275 family. http://togogenome.org/gene/243161:TC_RS04490 ^@ http://purl.uniprot.org/uniprot/Q9PJE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/243161:TC_RS03455 ^@ http://purl.uniprot.org/uniprot/Q9PJZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS03145 ^@ http://purl.uniprot.org/uniprot/P66517 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/243161:TC_RS00800 ^@ http://purl.uniprot.org/uniprot/Q9PLF2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/243161:TC_RS04665 ^@ http://purl.uniprot.org/uniprot/Q9PJB5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/243161:TC_RS04025 ^@ http://purl.uniprot.org/uniprot/Q9PJN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/243161:TC_RS04030 ^@ http://purl.uniprot.org/uniprot/Q9PJN5 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/243161:TC_RS02105 ^@ http://purl.uniprot.org/uniprot/Q9PKP3 ^@ Caution|||Function|||PTM|||Similarity ^@ Autophosphorylated on serine and threonine residues.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.|||Gln-136 is present instead of the conserved Asp which is expected to be an active site residue.|||Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth. http://togogenome.org/gene/243161:TC_RS03400 ^@ http://purl.uniprot.org/uniprot/Q9PK04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/243161:TC_RS01350 ^@ http://purl.uniprot.org/uniprot/Q9PL41 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS03740 ^@ http://purl.uniprot.org/uniprot/Q9PJT8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS03775 ^@ http://purl.uniprot.org/uniprot/Q9PJT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily.|||Binds 2 divalent metal cations.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipooligosaccharide (LOS) to the outer membrane of the cell. http://togogenome.org/gene/243161:TC_RS03535 ^@ http://purl.uniprot.org/uniprot/Q9PJX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Part of an ATP-driven transport system TC_0696/TC_0697/TC_0698 for a metal. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/243161:TC_RS03110 ^@ http://purl.uniprot.org/uniprot/Q9PK57 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).|||Homodimer.|||The N-terminal domain contains the HPr binding site, the central domain the pyrophosphate/phosphate carrier histidine, and the C-terminal domain the pyruvate binding site.|||The reaction takes place in three steps, mediated by a phosphocarrier histidine residue located on the surface of the central domain. The two first partial reactions are catalyzed at an active site located on the N-terminal domain, and the third partial reaction is catalyzed at an active site located on the C-terminal domain. For catalytic turnover, the central domain swivels from the concave surface of the N-terminal domain to that of the C-terminal domain. http://togogenome.org/gene/243161:TC_RS00950 ^@ http://purl.uniprot.org/uniprot/P24286 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/243161:TC_RS04005 ^@ http://purl.uniprot.org/uniprot/Q9PJN9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/243161:TC_RS04435 ^@ http://purl.uniprot.org/uniprot/Q9PJF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS04610 ^@ http://purl.uniprot.org/uniprot/Q9PJC4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/243161:TC_RS00215 ^@ http://purl.uniprot.org/uniprot/Q9PLQ3 ^@ Similarity ^@ Belongs to the chlamydial CPn_0705/CT_671/TC_0042 family. http://togogenome.org/gene/243161:TC_RS02940 ^@ http://purl.uniprot.org/uniprot/Q9PK86 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/243161:TC_RS02110 ^@ http://purl.uniprot.org/uniprot/Q9PKP2 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/243161:TC_RS00835 ^@ http://purl.uniprot.org/uniprot/Q9PLE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/243161:TC_RS02430 ^@ http://purl.uniprot.org/uniprot/Q9PKI2 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/243161:TC_RS03730 ^@ http://purl.uniprot.org/uniprot/Q9PJU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS00465 ^@ http://purl.uniprot.org/uniprot/Q9PLL1 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/243161:TC_RS00190 ^@ http://purl.uniprot.org/uniprot/Q9PLQ8 ^@ Similarity ^@ Belongs to the chlamydial CPn_0710/CT_666/TC_0037 family. http://togogenome.org/gene/243161:TC_RS01490 ^@ http://purl.uniprot.org/uniprot/Q9PL12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/243161:TC_RS03985 ^@ http://purl.uniprot.org/uniprot/Q9PJP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/243161:TC_RS01070 ^@ http://purl.uniprot.org/uniprot/Q9PL95 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/243161:TC_RS04080 ^@ http://purl.uniprot.org/uniprot/Q9PJM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/243161:TC_RS02835 ^@ http://purl.uniprot.org/uniprot/Q9PKA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS01385 ^@ http://purl.uniprot.org/uniprot/Q9PL34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chlamydial CPn_0442/CT_006/TC_0274 family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01555 ^@ http://purl.uniprot.org/uniprot/Q9PKZ8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/243161:TC_RS03295 ^@ http://purl.uniprot.org/uniprot/Q9PK23 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/243161:TC_RS02455 ^@ http://purl.uniprot.org/uniprot/Q9PKH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03040 ^@ http://purl.uniprot.org/uniprot/Q9PK71 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/243161:TC_RS04165 ^@ http://purl.uniprot.org/uniprot/Q9PJK9 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/243161:TC_RS01220 ^@ http://purl.uniprot.org/uniprot/Q9PL66 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/243161:TC_RS04560 ^@ http://purl.uniprot.org/uniprot/Q9PJD1 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/243161:TC_RS03545 ^@ http://purl.uniprot.org/uniprot/Q9PJX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS00540 ^@ http://purl.uniprot.org/uniprot/Q9PLJ6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/243161:TC_RS00415 ^@ http://purl.uniprot.org/uniprot/Q9PLM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/243161:TC_RS02740 ^@ http://purl.uniprot.org/uniprot/Q9PKC6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02545 ^@ http://purl.uniprot.org/uniprot/Q9PKG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS02705 ^@ http://purl.uniprot.org/uniprot/Q9PKD2 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/243161:TC_RS01550 ^@ http://purl.uniprot.org/uniprot/Q9PKZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer. http://togogenome.org/gene/243161:TC_RS02295 ^@ http://purl.uniprot.org/uniprot/Q9PKK7 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/243161:TC_RS00220 ^@ http://purl.uniprot.org/uniprot/Q9PLQ2 ^@ Similarity ^@ Belongs to the FliN/MopA/SpaO family. http://togogenome.org/gene/243161:TC_RS01450 ^@ http://purl.uniprot.org/uniprot/Q9PL20 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/243161:TC_RS01255 ^@ http://purl.uniprot.org/uniprot/Q9PL59 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/243161:TC_RS00360 ^@ http://purl.uniprot.org/uniprot/Q9PLN1 ^@ Similarity ^@ Belongs to the chlamydial CPn_0675/CT_696/TC_0068 family. http://togogenome.org/gene/243161:TC_RS03435 ^@ http://purl.uniprot.org/uniprot/Q9PK00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS04645 ^@ http://purl.uniprot.org/uniprot/Q9PJB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. http://togogenome.org/gene/243161:TC_RS02840 ^@ http://purl.uniprot.org/uniprot/Q9PKA6 ^@ Similarity ^@ Belongs to the chlamydial CPn_0065/CT_288/TC_0561 family. http://togogenome.org/gene/243161:TC_RS03785 ^@ http://purl.uniprot.org/uniprot/Q9PJT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer. http://togogenome.org/gene/243161:TC_RS03375 ^@ http://purl.uniprot.org/uniprot/Q9PK08 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/243161:TC_RS01615 ^@ http://purl.uniprot.org/uniprot/Q9PKY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/243161:TC_RS04105 ^@ http://purl.uniprot.org/uniprot/Q9PJM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS03995 ^@ http://purl.uniprot.org/uniprot/Q9PJP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/243161:TC_RS01140 ^@ http://purl.uniprot.org/uniprot/Q9PL81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS01160 ^@ http://purl.uniprot.org/uniprot/Q9PL77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/243161:TC_RS00380 ^@ http://purl.uniprot.org/uniprot/Q9PLM7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/243161:TC_RS00020 ^@ http://purl.uniprot.org/uniprot/Q9PLU1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity). http://togogenome.org/gene/243161:TC_RS03335 ^@ http://purl.uniprot.org/uniprot/Q9PK15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS02730 ^@ http://purl.uniprot.org/uniprot/P64387 ^@ Function|||Similarity ^@ Belongs to the bacterial histone-like protein family.|||Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. http://togogenome.org/gene/243161:TC_RS01640 ^@ http://purl.uniprot.org/uniprot/Q9PKY4 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/243161:TC_RS00335 ^@ http://purl.uniprot.org/uniprot/Q9PLN6 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/243161:TC_RS01030 ^@ http://purl.uniprot.org/uniprot/Q9PLA3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/243161:TC_RS01150 ^@ http://purl.uniprot.org/uniprot/Q9PL79 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/243161:TC_RS00565 ^@ http://purl.uniprot.org/uniprot/Q9PLJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/243161:TC_RS03755 ^@ http://purl.uniprot.org/uniprot/Q9PJT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03155 ^@ http://purl.uniprot.org/uniprot/Q9PK50 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/243161:TC_RS03130 ^@ http://purl.uniprot.org/uniprot/Q9PK55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS00760 ^@ http://purl.uniprot.org/uniprot/Q9PLG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02610 ^@ http://purl.uniprot.org/uniprot/Q9PKF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/243161:TC_RS00155 ^@ http://purl.uniprot.org/uniprot/Q9PLR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02330 ^@ http://purl.uniprot.org/uniprot/Q9PKK0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/243161:TC_RS04505 ^@ http://purl.uniprot.org/uniprot/Q9PJE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TolB family.|||Periplasm http://togogenome.org/gene/243161:TC_RS03780 ^@ http://purl.uniprot.org/uniprot/Q9PJT1 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/243161:TC_RS04295 ^@ http://purl.uniprot.org/uniprot/Q9PJI3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||The active site is a redox-active disulfide bond.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). http://togogenome.org/gene/243161:TC_RS04155 ^@ http://purl.uniprot.org/uniprot/Q9PJL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/243161:TC_RS04430 ^@ http://purl.uniprot.org/uniprot/Q9PJF6 ^@ Similarity ^@ Belongs to the chlamydial CPn_0803/CT_584/TC_0873 family. http://togogenome.org/gene/243161:TC_RS03685 ^@ http://purl.uniprot.org/uniprot/Q9PJU9 ^@ Developmental Stage|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell outer membrane|||In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).|||It is present but the disulfide bonds are reduced in reticulate bodies (RBs).|||Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB). http://togogenome.org/gene/243161:TC_RS00585 ^@ http://purl.uniprot.org/uniprot/Q9PLI7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Cell inner membrane|||Consists of an N-terminal domain, which is sufficient for the localization to the septal ring and is required for cell division, followed by a linker domain, and a C-terminal domain, which forms the translocation motor involved in chromosome segregation. The C-terminal domain can be further subdivided into alpha, beta and gamma subdomains. The alpha and beta subdomains form the DNA pump, and the gamma subdomain is a regulatory subdomain (By similarity).|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).|||Homohexamer. Forms a ring that surrounds DNA (By similarity). http://togogenome.org/gene/243161:TC_RS01125 ^@ http://purl.uniprot.org/uniprot/Q9PL83 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/243161:TC_RS04160 ^@ http://purl.uniprot.org/uniprot/Q9PJL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/243161:TC_RS03510 ^@ http://purl.uniprot.org/uniprot/Q9PJY3 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS00870 ^@ http://purl.uniprot.org/uniprot/P66289 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/243161:TC_RS01505 ^@ http://purl.uniprot.org/uniprot/Q9PL09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/243161:TC_RS00370 ^@ http://purl.uniprot.org/uniprot/Q9PLM9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/243161:TC_RS01325 ^@ http://purl.uniprot.org/uniprot/Q9PL47 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS02200 ^@ http://purl.uniprot.org/uniprot/Q9PKM4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/243161:TC_RS02205 ^@ http://purl.uniprot.org/uniprot/Q9PKM3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/243161:TC_RS01995 ^@ http://purl.uniprot.org/uniprot/Q9PKR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/243161:TC_RS02955 ^@ http://purl.uniprot.org/uniprot/Q9PK83 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/243161:TC_RS01495 ^@ http://purl.uniprot.org/uniprot/Q9PL11 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/243161:TC_RS01580 ^@ http://purl.uniprot.org/uniprot/P38019 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity). http://togogenome.org/gene/243161:TC_RS02305 ^@ http://purl.uniprot.org/uniprot/Q9PKK5 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/243161:TC_RS02235 ^@ http://purl.uniprot.org/uniprot/Q9PKL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family. BdbC subfamily.|||Cell inner membrane|||Required for disulfide bond formation in some proteins. http://togogenome.org/gene/243161:TC_RS02620 ^@ http://purl.uniprot.org/uniprot/Q9PKE9 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/243161:TC_RS00500 ^@ http://purl.uniprot.org/uniprot/Q9PLK4 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/243161:TC_RS01575 ^@ http://purl.uniprot.org/uniprot/Q9PKZ4 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/243161:TC_RS00320 ^@ http://purl.uniprot.org/uniprot/Q9PLN9 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity). http://togogenome.org/gene/243161:TC_RS01935 ^@ http://purl.uniprot.org/uniprot/Q9PKS5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent (By similarity).|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).|||The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity). http://togogenome.org/gene/243161:TC_RS02390 ^@ http://purl.uniprot.org/uniprot/Q9PKI8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/243161:TC_RS04525 ^@ http://purl.uniprot.org/uniprot/Q9PJD7 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/243161:TC_RS00065 ^@ http://purl.uniprot.org/uniprot/Q9PLT3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/243161:TC_RS04385 ^@ http://purl.uniprot.org/uniprot/Q9PJG5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). http://togogenome.org/gene/243161:TC_RS03000 ^@ http://purl.uniprot.org/uniprot/Q9PK76 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/243161:TC_RS00205 ^@ http://purl.uniprot.org/uniprot/Q9PLQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS01165 ^@ http://purl.uniprot.org/uniprot/P66428 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/243161:TC_RS02550 ^@ http://purl.uniprot.org/uniprot/Q9PKG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS04190 ^@ http://purl.uniprot.org/uniprot/Q9PJK4 ^@ Similarity ^@ Belongs to the chlamydial CPn_0658/CT_538/TC_0825 family. http://togogenome.org/gene/243161:TC_RS01100 ^@ http://purl.uniprot.org/uniprot/Q9PL89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03495 ^@ http://purl.uniprot.org/uniprot/Q9PJY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/243161:TC_RS01115 ^@ http://purl.uniprot.org/uniprot/P66268 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/243161:TC_RS00655 ^@ http://purl.uniprot.org/uniprot/Q9PLH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS00780 ^@ http://purl.uniprot.org/uniprot/Q9PLF6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/243161:TC_RS04590 ^@ http://purl.uniprot.org/uniprot/Q9PJC6 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/243161:TC_RS03555 ^@ http://purl.uniprot.org/uniprot/Q9PJX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/243161:TC_RS04495 ^@ http://purl.uniprot.org/uniprot/Q9PJE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01040 ^@ http://purl.uniprot.org/uniprot/Q9PLA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS00070 ^@ http://purl.uniprot.org/uniprot/Q9PLT2 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/243161:TC_RS00015 ^@ http://purl.uniprot.org/uniprot/Q9PLU2 ^@ Similarity ^@ Belongs to the chlamydial CPn_0742/CT_635/TC_0003 family. http://togogenome.org/gene/243161:TC_RS00040 ^@ http://purl.uniprot.org/uniprot/Q9PLT8 ^@ Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/243161:TC_RS03695 ^@ http://purl.uniprot.org/uniprot/Q9PJU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS00735 ^@ http://purl.uniprot.org/uniprot/Q9PLG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03310 ^@ http://purl.uniprot.org/uniprot/Q9PK20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Catalyzes the exchange of L-arginine for agmatine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).|||Cell inner membrane http://togogenome.org/gene/243161:TC_RS01230 ^@ http://purl.uniprot.org/uniprot/Q9PL64 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/243161:TC_RS01425 ^@ http://purl.uniprot.org/uniprot/Q9PL26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/243161:TC_RS00075 ^@ http://purl.uniprot.org/uniprot/Q9PLT1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/243161:TC_RS02030 ^@ http://purl.uniprot.org/uniprot/Q9PKQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS04135 ^@ http://purl.uniprot.org/uniprot/Q9PJL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS01225 ^@ http://purl.uniprot.org/uniprot/Q9PL65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01760 ^@ http://purl.uniprot.org/uniprot/Q9PKW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein such as NqrB and NqrC, two subunits of the NQR complex. http://togogenome.org/gene/243161:TC_RS04700 ^@ http://purl.uniprot.org/uniprot/Q46435 ^@ Similarity ^@ Belongs to the 'phage' integrase family. http://togogenome.org/gene/243161:TC_RS04225 ^@ http://purl.uniprot.org/uniprot/Q9PJJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Cell membrane|||Transport protein for sugar phosphate uptake. http://togogenome.org/gene/243161:TC_RS02890 ^@ http://purl.uniprot.org/uniprot/Q9PK96 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Has a putative N-terminal zinc-finger, a middle region with homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/243161:TC_RS02400 ^@ http://purl.uniprot.org/uniprot/Q9PKI6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/243161:TC_RS03075 ^@ http://purl.uniprot.org/uniprot/Q9PK64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/243161:TC_RS01735 ^@ http://purl.uniprot.org/uniprot/Q9PKW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell inner membrane http://togogenome.org/gene/243161:TC_RS02595 ^@ http://purl.uniprot.org/uniprot/Q9PKF4 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/243161:TC_RS02630 ^@ http://purl.uniprot.org/uniprot/Q9PKE7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/243161:TC_RS00560 ^@ http://purl.uniprot.org/uniprot/Q9PLJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chlamydial CPn_0875/CT_734/TC_0107 family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS04535 ^@ http://purl.uniprot.org/uniprot/Q9PJD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/243161:TC_RS00805 ^@ http://purl.uniprot.org/uniprot/Q9PLF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/243161:TC_RS01465 ^@ http://purl.uniprot.org/uniprot/Q9PL17 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS04210 ^@ http://purl.uniprot.org/uniprot/Q9PJK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family.|||Cell outer membrane|||PPIases accelerate the folding of proteins. http://togogenome.org/gene/243161:TC_RS01890 ^@ http://purl.uniprot.org/uniprot/Q9PKT2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/243161:TC_RS03625 ^@ http://purl.uniprot.org/uniprot/Q9PJV9 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/243161:TC_RS00945 ^@ http://purl.uniprot.org/uniprot/Q9PLC1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/243161:TC_RS02590 ^@ http://purl.uniprot.org/uniprot/Q9PKF5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/243161:TC_RS01480 ^@ http://purl.uniprot.org/uniprot/Q9PL14 ^@ Similarity ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily. http://togogenome.org/gene/243161:TC_RS00690 ^@ http://purl.uniprot.org/uniprot/Q9PLH3 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/243161:TC_RS02005 ^@ http://purl.uniprot.org/uniprot/Q9PKR1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/243161:TC_RS00175 ^@ http://purl.uniprot.org/uniprot/Q9PLR1 ^@ Similarity ^@ Belongs to the chlamydial CPn_0713/CT_663/TC_0034 family. http://togogenome.org/gene/243161:TC_RS01920 ^@ http://purl.uniprot.org/uniprot/Q59322 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||By stress.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/243161:TC_RS01110 ^@ http://purl.uniprot.org/uniprot/Q9PL86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/243161:TC_RS01675 ^@ http://purl.uniprot.org/uniprot/Q9PKX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS03650 ^@ http://purl.uniprot.org/uniprot/Q9PJV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/243161:TC_RS00730 ^@ http://purl.uniprot.org/uniprot/Q9PLG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane http://togogenome.org/gene/243161:TC_RS03390 ^@ http://purl.uniprot.org/uniprot/Q9PK06 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/243161:TC_RS02315 ^@ http://purl.uniprot.org/uniprot/Q9PKK3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/243161:TC_RS04140 ^@ http://purl.uniprot.org/uniprot/Q9PJL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/243161:TC_RS03610 ^@ http://purl.uniprot.org/uniprot/Q9PJW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS03010 ^@ http://purl.uniprot.org/uniprot/Q9PK74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/243161:TC_RS01000 ^@ http://purl.uniprot.org/uniprot/Q9PLB0 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS04415 ^@ http://purl.uniprot.org/uniprot/Q9PJF9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS01800 ^@ http://purl.uniprot.org/uniprot/Q9PKV0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/243161:TC_RS01075 ^@ http://purl.uniprot.org/uniprot/Q9PL94 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/243161:TC_RS03720 ^@ http://purl.uniprot.org/uniprot/Q9PJU2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/243161:TC_RS03285 ^@ http://purl.uniprot.org/uniprot/Q9PK25 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02950 ^@ http://purl.uniprot.org/uniprot/Q9PK84 ^@ Similarity ^@ Belongs to the chlamydial CPn_0087/CT3_09/TC_0583 family. http://togogenome.org/gene/243161:TC_RS03170 ^@ http://purl.uniprot.org/uniprot/Q9PK47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/243161:TC_RS01730 ^@ http://purl.uniprot.org/uniprot/Q9PKW8 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/243161:TC_RS00625 ^@ http://purl.uniprot.org/uniprot/Q9PLI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/243161:TC_RS00410 ^@ http://purl.uniprot.org/uniprot/Q9PLM1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/243161:TC_RS00570 ^@ http://purl.uniprot.org/uniprot/Q9PLJ0 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/243161:TC_RS01055 ^@ http://purl.uniprot.org/uniprot/Q9PL98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/243161:TC_RS02485 ^@ http://purl.uniprot.org/uniprot/Q9PKH2 ^@ Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN. http://togogenome.org/gene/243161:TC_RS00520 ^@ http://purl.uniprot.org/uniprot/Q9PLK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS03245 ^@ http://purl.uniprot.org/uniprot/Q9PK33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/243161:TC_RS00285 ^@ http://purl.uniprot.org/uniprot/P75024 ^@ Caution|||Developmental Stage|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chlamydial porin (CP) (TC 1.B.2) family.|||Cell outer membrane|||In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).|||It is present but some of the disulfide bonds are reduced in reticulate bodies (RBs).|||Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).|||Permits diffusion of specific solutes through the outer membrane.|||Was originally (PubMed:1937036, PubMed:1718870) thought to originate from Chlamydia trachomatis. http://togogenome.org/gene/243161:TC_RS03705 ^@ http://purl.uniprot.org/uniprot/Q9PJU5 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/243161:TC_RS03205 ^@ http://purl.uniprot.org/uniprot/Q9PK40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/243161:TC_RS02925 ^@ http://purl.uniprot.org/uniprot/Q9PK89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS02475 ^@ http://purl.uniprot.org/uniprot/Q9PKH4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/243161:TC_RS00440 ^@ http://purl.uniprot.org/uniprot/Q9PLL6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS01060 ^@ http://purl.uniprot.org/uniprot/Q9PL97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.|||Periplasm http://togogenome.org/gene/243161:TC_RS02460 ^@ http://purl.uniprot.org/uniprot/Q9PKH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS04565 ^@ http://purl.uniprot.org/uniprot/Q9PJD0 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/243161:TC_RS02015 ^@ http://purl.uniprot.org/uniprot/Q9PKQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/243161:TC_RS01830 ^@ http://purl.uniprot.org/uniprot/Q9PKU4 ^@ Caution|||Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/243161:TC_RS01985 ^@ http://purl.uniprot.org/uniprot/Q9PKR5 ^@ Function|||Subunit ^@ Homodimer.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/243161:TC_RS01500 ^@ http://purl.uniprot.org/uniprot/Q9PL10 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/243161:TC_RS03085 ^@ http://purl.uniprot.org/uniprot/Q9PK62 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/243161:TC_RS03180 ^@ http://purl.uniprot.org/uniprot/Q9PK45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/243161:TC_RS03585 ^@ http://purl.uniprot.org/uniprot/Q9PJW8 ^@ Similarity ^@ Belongs to the chlamydial CPn_0512/CT_425/TC_0708 family. http://togogenome.org/gene/243161:TC_RS02715 ^@ http://purl.uniprot.org/uniprot/Q9PKD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS01870 ^@ http://purl.uniprot.org/uniprot/Q9PKT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/243161:TC_RS01375 ^@ http://purl.uniprot.org/uniprot/Q9PL36 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/243161:TC_RS03725 ^@ http://purl.uniprot.org/uniprot/Q9PJU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01725 ^@ http://purl.uniprot.org/uniprot/Q9PKW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell inner membrane|||Part of an ATP-driven transport system TC_0338/TC_0339/TC_0341/TC_0342 for a metal. http://togogenome.org/gene/243161:TC_RS04735 ^@ http://purl.uniprot.org/uniprot/Q46442 ^@ Similarity ^@ Belongs to the UPF0137 (pGP6-D) family. http://togogenome.org/gene/243161:TC_RS00995 ^@ http://purl.uniprot.org/uniprot/Q9PLB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/243161:TC_RS02810 ^@ http://purl.uniprot.org/uniprot/Q9PKB2 ^@ Cofactor|||Similarity ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently. http://togogenome.org/gene/243161:TC_RS02010 ^@ http://purl.uniprot.org/uniprot/Q9PKR0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS04585 ^@ http://purl.uniprot.org/uniprot/P82602 ^@ Similarity ^@ In the C-terminal section; belongs to the DHPS family.|||In the N-terminal section; belongs to the HPPK family. http://togogenome.org/gene/243161:TC_RS01635 ^@ http://purl.uniprot.org/uniprot/Q9PKY5 ^@ Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/243161:TC_RS00400 ^@ http://purl.uniprot.org/uniprot/Q9PLM3 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/243161:TC_RS03425 ^@ http://purl.uniprot.org/uniprot/P23575 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/243161:TC_RS03935 ^@ http://purl.uniprot.org/uniprot/Q9PJQ2 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/243161:TC_RS03880 ^@ http://purl.uniprot.org/uniprot/Q9PJR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS01515 ^@ http://purl.uniprot.org/uniprot/Q9PL07 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/243161:TC_RS03605 ^@ http://purl.uniprot.org/uniprot/Q9PJW3 ^@ Similarity ^@ Belongs to the UPF0158 family. http://togogenome.org/gene/243161:TC_RS01765 ^@ http://purl.uniprot.org/uniprot/Q9PKW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/243161:TC_RS04710 ^@ http://purl.uniprot.org/uniprot/Q46437 ^@ Similarity ^@ Belongs to the helicase family. DnaB subfamily. http://togogenome.org/gene/243161:TC_RS03005 ^@ http://purl.uniprot.org/uniprot/Q9PK75 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/243161:TC_RS02995 ^@ http://purl.uniprot.org/uniprot/Q9PK77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/243161:TC_RS01795 ^@ http://purl.uniprot.org/uniprot/Q9PKV2 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/243161:TC_RS01905 ^@ http://purl.uniprot.org/uniprot/Q9PKS9 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/243161:TC_RS03620 ^@ http://purl.uniprot.org/uniprot/Q9PJW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS00650 ^@ http://purl.uniprot.org/uniprot/Q9PLH8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS04330 ^@ http://purl.uniprot.org/uniprot/Q9PJH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/243161:TC_RS04115 ^@ http://purl.uniprot.org/uniprot/Q9PJL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/243161:TC_RS02860 ^@ http://purl.uniprot.org/uniprot/Q9PKA2 ^@ Function|||Similarity ^@ Belongs to the dUTPase family.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/243161:TC_RS02490 ^@ http://purl.uniprot.org/uniprot/Q9PKH1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/243161:TC_RS04175 ^@ http://purl.uniprot.org/uniprot/Q9PJK7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/243161:TC_RS01865 ^@ http://purl.uniprot.org/uniprot/Q9PKT7 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Homodimer.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/243161:TC_RS01975 ^@ http://purl.uniprot.org/uniprot/Q9PKR7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/243161:TC_RS01470 ^@ http://purl.uniprot.org/uniprot/Q9PL16 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1 (By similarity).|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/243161:TC_RS02990 ^@ http://purl.uniprot.org/uniprot/Q9PK78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex (By similarity). http://togogenome.org/gene/243161:TC_RS00770 ^@ http://purl.uniprot.org/uniprot/Q9PLF8 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/243161:TC_RS02915 ^@ http://purl.uniprot.org/uniprot/Q9PK91 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/243161:TC_RS03655 ^@ http://purl.uniprot.org/uniprot/P66371 ^@ Caution|||Function|||Similarity|||Subunit ^@ Because the enzyme that would modify Asp-89 to 3-methylthioaspartic acid has not been found in the proteome of this organism, that modification is not predicted.|||Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/243161:TC_RS03115 ^@ http://purl.uniprot.org/uniprot/Q9PK56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HPr family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/243161:TC_RS01925 ^@ http://purl.uniprot.org/uniprot/P17204 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/243161:TC_RS03030 ^@ http://purl.uniprot.org/uniprot/P65107 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/243161:TC_RS02790 ^@ http://purl.uniprot.org/uniprot/Q9PKB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/243161:TC_RS03270 ^@ http://purl.uniprot.org/uniprot/Q9PK28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS04660 ^@ http://purl.uniprot.org/uniprot/Q9PJB6 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/243161:TC_RS02575 ^@ http://purl.uniprot.org/uniprot/Q9PKF8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS01045 ^@ http://purl.uniprot.org/uniprot/Q9PLA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/243161:TC_RS02910 ^@ http://purl.uniprot.org/uniprot/Q9PK92 ^@ Function|||PTM|||Similarity ^@ Autophosphorylated on serine and threonine residues.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.|||Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth. http://togogenome.org/gene/243161:TC_RS03710 ^@ http://purl.uniprot.org/uniprot/Q9PJU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS00955 ^@ http://purl.uniprot.org/uniprot/Q46398 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/243161:TC_RS00890 ^@ http://purl.uniprot.org/uniprot/Q9PLD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/243161:TC_RS00700 ^@ http://purl.uniprot.org/uniprot/Q9PLH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). http://togogenome.org/gene/243161:TC_RS03020 ^@ http://purl.uniprot.org/uniprot/Q9PK73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/243161:TC_RS00920 ^@ http://purl.uniprot.org/uniprot/Q9PLC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/243161:TC_RS02440 ^@ http://purl.uniprot.org/uniprot/Q9PKI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/243161:TC_RS04170 ^@ http://purl.uniprot.org/uniprot/Q9PJK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane http://togogenome.org/gene/243161:TC_RS03745 ^@ http://purl.uniprot.org/uniprot/Q9PJT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS00305 ^@ http://purl.uniprot.org/uniprot/Q9PLP2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/243161:TC_RS02135 ^@ http://purl.uniprot.org/uniprot/Q9PKN7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/243161:TC_RS02580 ^@ http://purl.uniprot.org/uniprot/Q9PKF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/243161:TC_RS02930 ^@ http://purl.uniprot.org/uniprot/Q9PK88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/243161:TC_RS00940 ^@ http://purl.uniprot.org/uniprot/P49607 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/243161:TC_RS00935 ^@ http://purl.uniprot.org/uniprot/Q9PLC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/243161:TC_RS04040 ^@ http://purl.uniprot.org/uniprot/Q9PJN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/243161:TC_RS01910 ^@ http://purl.uniprot.org/uniprot/Q9PKS8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family.|||Homohexamer. http://togogenome.org/gene/243161:TC_RS04120 ^@ http://purl.uniprot.org/uniprot/P66481 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/243161:TC_RS04200 ^@ http://purl.uniprot.org/uniprot/Q9PJK3 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family.|||Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. http://togogenome.org/gene/243161:TC_RS00900 ^@ http://purl.uniprot.org/uniprot/Q9PLC9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Binds two Mg(2+) per subunit.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/243161:TC_RS00875 ^@ http://purl.uniprot.org/uniprot/Q9PLD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/243161:TC_RS01215 ^@ http://purl.uniprot.org/uniprot/Q9PL67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS00240 ^@ http://purl.uniprot.org/uniprot/Q9PLP9 ^@ Function|||Similarity ^@ Belongs to the ATP:guanido phosphotransferase family.|||Catalyzes the specific phosphorylation of arginine residues in proteins. http://togogenome.org/gene/243161:TC_RS03290 ^@ http://purl.uniprot.org/uniprot/P56961 ^@ Function|||Similarity ^@ Bifunctional enzyme that catalyzes two sequential steps of the aromatic amino acids biosynthetic pathway. In the first reaction, the AroD domain catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate; in the second reaction, the AroE domain catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||In the C-terminal section; belongs to the shikimate dehydrogenase family.|||In the N-terminal section; belongs to the type-I 3-dehydroquinase family. http://togogenome.org/gene/243161:TC_RS04545 ^@ http://purl.uniprot.org/uniprot/Q9PJD4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/243161:TC_RS03460 ^@ http://purl.uniprot.org/uniprot/Q9PJZ4 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/243161:TC_RS03475 ^@ http://purl.uniprot.org/uniprot/Q9PJZ1 ^@ Function|||Subunit ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.|||Homotrimer. http://togogenome.org/gene/243161:TC_RS03165 ^@ http://purl.uniprot.org/uniprot/Q9PK48 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/243161:TC_RS01210 ^@ http://purl.uniprot.org/uniprot/Q9PL68 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/243161:TC_RS02975 ^@ http://purl.uniprot.org/uniprot/Q9PK79 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/243161:TC_RS04440 ^@ http://purl.uniprot.org/uniprot/Q9PJF4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/243161:TC_RS03670 ^@ http://purl.uniprot.org/uniprot/Q9PJV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS03275 ^@ http://purl.uniprot.org/uniprot/Q9PK27 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS03445 ^@ http://purl.uniprot.org/uniprot/Q9PJZ7 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/243161:TC_RS00755 ^@ http://purl.uniprot.org/uniprot/Q9PLG1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm|||In the C-terminal section; belongs to the D-alanine--D-alanine ligase family.|||In the N-terminal section; belongs to the MurCDEF family. http://togogenome.org/gene/243161:TC_RS04220 ^@ http://purl.uniprot.org/uniprot/Q9PJJ9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS04075 ^@ http://purl.uniprot.org/uniprot/Q9PJM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/243161:TC_RS01845 ^@ http://purl.uniprot.org/uniprot/Q9PKU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/243161:TC_RS00315 ^@ http://purl.uniprot.org/uniprot/Q9PLP0 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/243161:TC_RS00545 ^@ http://purl.uniprot.org/uniprot/Q9PLJ5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/243161:TC_RS01510 ^@ http://purl.uniprot.org/uniprot/Q9PL08 ^@ Similarity ^@ Belongs to the chlamydial CPn_0121/CT_031/TC_0300 family. http://togogenome.org/gene/243161:TC_RS03615 ^@ http://purl.uniprot.org/uniprot/Q9PJW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/243161:TC_RS02605 ^@ http://purl.uniprot.org/uniprot/Q9PKF2 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/243161:TC_RS01755 ^@ http://purl.uniprot.org/uniprot/Q9PKW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/243161:TC_RS03065 ^@ http://purl.uniprot.org/uniprot/Q9PK66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/243161:TC_RS04100 ^@ http://purl.uniprot.org/uniprot/Q9PJM2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/243161:TC_RS01340 ^@ http://purl.uniprot.org/uniprot/Q9PL44 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS04130 ^@ http://purl.uniprot.org/uniprot/Q9PJL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/243161:TC_RS01485 ^@ http://purl.uniprot.org/uniprot/Q9PL13 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/243161:TC_RS01420 ^@ http://purl.uniprot.org/uniprot/Q9PL27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/243161:TC_RS00865 ^@ http://purl.uniprot.org/uniprot/Q9PLD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/243161:TC_RS03280 ^@ http://purl.uniprot.org/uniprot/Q9PK26 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/243161:TC_RS01860 ^@ http://purl.uniprot.org/uniprot/P38016 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity). http://togogenome.org/gene/243161:TC_RS01990 ^@ http://purl.uniprot.org/uniprot/Q9PKR4 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/243161:TC_RS00525 ^@ http://purl.uniprot.org/uniprot/Q9PLJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/243161:TC_RS04065 ^@ http://purl.uniprot.org/uniprot/Q9PJM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/243161:TC_RS02760 ^@ http://purl.uniprot.org/uniprot/Q9PKC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/243161:TC_RS00390 ^@ http://purl.uniprot.org/uniprot/Q9PLM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/243161:TC_RS00300 ^@ http://purl.uniprot.org/uniprot/Q9PLP3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/243161:TC_RS01840 ^@ http://purl.uniprot.org/uniprot/Q9PKU2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/243161:TC_RS00850 ^@ http://purl.uniprot.org/uniprot/Q9PLE1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS04555 ^@ http://purl.uniprot.org/uniprot/Q9PJD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/243161:TC_RS00405 ^@ http://purl.uniprot.org/uniprot/Q9PLM2 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/243161:TC_RS00795 ^@ http://purl.uniprot.org/uniprot/Q9PLF3 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/243161:TC_RS03305 ^@ http://purl.uniprot.org/uniprot/Q9PK21 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family.|||Binds 1 pyruvoyl group covalently per subunit.|||Cytoplasm|||Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).|||Trimer of an alpha-beta dimer. http://togogenome.org/gene/243161:TC_RS03600 ^@ http://purl.uniprot.org/uniprot/Q9PJW4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/243161:TC_RS01685 ^@ http://purl.uniprot.org/uniprot/Q9PKX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/243161:TC_RS01300 ^@ http://purl.uniprot.org/uniprot/Q9PL51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/243161:TC_RS00620 ^@ http://purl.uniprot.org/uniprot/Q9PLI3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrF family.|||Binds 1 [2Fe-2S] cluster.|||Cell inner membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. http://togogenome.org/gene/243161:TC_RS03100 ^@ http://purl.uniprot.org/uniprot/Q9PK59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/243161:TC_RS02280 ^@ http://purl.uniprot.org/uniprot/Q9PKL0 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/243161:TC_RS04405 ^@ http://purl.uniprot.org/uniprot/Q9PJG1 ^@ Similarity ^@ Belongs to the chlamydial CPn_0808/CT579/TC_0868 family. http://togogenome.org/gene/243161:TC_RS00790 ^@ http://purl.uniprot.org/uniprot/Q9PLF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/243161:TC_RS00665 ^@ http://purl.uniprot.org/uniprot/Q9PLH5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03235 ^@ http://purl.uniprot.org/uniprot/Q9PK35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS03595 ^@ http://purl.uniprot.org/uniprot/Q9PJW5 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/243161:TC_RS04420 ^@ http://purl.uniprot.org/uniprot/Q9PJF8 ^@ Similarity ^@ Belongs to the ParA family. http://togogenome.org/gene/243161:TC_RS00185 ^@ http://purl.uniprot.org/uniprot/Q9PLQ9 ^@ Similarity ^@ Belongs to the chlamydial CPn_0711/CT_665/TC_0036 family. http://togogenome.org/gene/243161:TC_RS02870 ^@ http://purl.uniprot.org/uniprot/Q9PKA0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Binds 1 Mn(2+) ion per subunit.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/243161:TC_RS02765 ^@ http://purl.uniprot.org/uniprot/Q9PKC1 ^@ Similarity ^@ Belongs to the chlamydial CPn_0422/CT_273/TC_0545 family. http://togogenome.org/gene/243161:TC_RS03095 ^@ http://purl.uniprot.org/uniprot/Q9PK60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity). http://togogenome.org/gene/243161:TC_RS04055 ^@ http://purl.uniprot.org/uniprot/Q9PJN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS02675 ^@ http://purl.uniprot.org/uniprot/Q9PKD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS00455 ^@ http://purl.uniprot.org/uniprot/Q9PLL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chlamydial OMP family.|||Cell outer membrane http://togogenome.org/gene/243161:TC_RS00530 ^@ http://purl.uniprot.org/uniprot/Q9PLJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS00960 ^@ http://purl.uniprot.org/uniprot/Q9PLC0 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/243161:TC_RS03250 ^@ http://purl.uniprot.org/uniprot/Q9PK32 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/243161:TC_RS03580 ^@ http://purl.uniprot.org/uniprot/Q9PJW9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/243161:TC_RS02935 ^@ http://purl.uniprot.org/uniprot/Q9PK87 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/243161:TC_RS03965 ^@ http://purl.uniprot.org/uniprot/Q9PJP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP/ATP translocase tlc family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS03210 ^@ http://purl.uniprot.org/uniprot/Q9PK39 ^@ Similarity ^@ Belongs to the chlamydial CPn_1058/CT_355/TC_0634 family. http://togogenome.org/gene/243161:TC_RS01475 ^@ http://purl.uniprot.org/uniprot/Q9PL15 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/243161:TC_RS02775 ^@ http://purl.uniprot.org/uniprot/Q9PKB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). http://togogenome.org/gene/243161:TC_RS04110 ^@ http://purl.uniprot.org/uniprot/Q9PJM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/243161:TC_RS02350 ^@ http://purl.uniprot.org/uniprot/Q9PKJ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/243161:TC_RS02275 ^@ http://purl.uniprot.org/uniprot/Q9PKL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS02655 ^@ http://purl.uniprot.org/uniprot/Q9PKE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/243161:TC_RS01050 ^@ http://purl.uniprot.org/uniprot/Q9PL99 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/243161:TC_RS01365 ^@ http://purl.uniprot.org/uniprot/Q9PL38 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/243161:TC_RS00895 ^@ http://purl.uniprot.org/uniprot/Q9PLD0 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). http://togogenome.org/gene/243161:TC_RS01145 ^@ http://purl.uniprot.org/uniprot/Q9PL80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS00005 ^@ http://purl.uniprot.org/uniprot/Q9PLU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).|||Homooctamer. http://togogenome.org/gene/243161:TC_RS02385 ^@ http://purl.uniprot.org/uniprot/Q9PKI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/243161:TC_RS01820 ^@ http://purl.uniprot.org/uniprot/Q9PKU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Membrane http://togogenome.org/gene/243161:TC_RS03480 ^@ http://purl.uniprot.org/uniprot/Q9PJZ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/243161:TC_RS00260 ^@ http://purl.uniprot.org/uniprot/P71148 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/243161:TC_RS04690 ^@ http://purl.uniprot.org/uniprot/Q9PJB1 ^@ Similarity ^@ Belongs to the UPF0159 family. http://togogenome.org/gene/243161:TC_RS04655 ^@ http://purl.uniprot.org/uniprot/Q9PJB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/243161:TC_RS00345 ^@ http://purl.uniprot.org/uniprot/Q9PLN4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/243161:TC_RS04020 ^@ http://purl.uniprot.org/uniprot/Q9PJN7 ^@ Similarity ^@ Belongs to the chlamydial CPn_0623/CT_504/TC_0791 family. http://togogenome.org/gene/243161:TC_RS04185 ^@ http://purl.uniprot.org/uniprot/Q9PJK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS04705 ^@ http://purl.uniprot.org/uniprot/Q46436 ^@ Similarity ^@ Belongs to the 'phage' integrase family. http://togogenome.org/gene/243161:TC_RS00885 ^@ http://purl.uniprot.org/uniprot/Q9PLD2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/243161:TC_RS03640 ^@ http://purl.uniprot.org/uniprot/P0A4A2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS03090 ^@ http://purl.uniprot.org/uniprot/Q9PK61 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/243161:TC_RS03200 ^@ http://purl.uniprot.org/uniprot/Q9PK41 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). http://togogenome.org/gene/243161:TC_RS03630 ^@ http://purl.uniprot.org/uniprot/Q9PJV8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/243161:TC_RS00635 ^@ http://purl.uniprot.org/uniprot/Q9PLI1 ^@ Developmental Stage|||Function|||Similarity ^@ Belongs to the histone H1/H5 family. HCT subfamily.|||Might have a role analogous to that of eukaryotic histone proteins.|||Specific to the EB (elementary body) form in the life cycle of chlamydiae. http://togogenome.org/gene/243161:TC_RS00130 ^@ http://purl.uniprot.org/uniprot/Q9PLS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS01085 ^@ http://purl.uniprot.org/uniprot/Q9PL92 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/243161:TC_RS01535 ^@ http://purl.uniprot.org/uniprot/Q9PL02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chlamydial CPn_0129/CT_036/TC_0306 family.|||Cell membrane http://togogenome.org/gene/243161:TC_RS03830 ^@ http://purl.uniprot.org/uniprot/Q9PJS3 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/243161:TC_RS01645 ^@ http://purl.uniprot.org/uniprot/Q9PKY3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/243161:TC_RS03645 ^@ http://purl.uniprot.org/uniprot/Q9PJV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).|||Cytoplasm http://togogenome.org/gene/243161:TC_RS00975 ^@ http://purl.uniprot.org/uniprot/Q9PLB7 ^@ Function ^@ Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. http://togogenome.org/gene/243161:TC_RS02795 ^@ http://purl.uniprot.org/uniprot/Q9PKB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrC family.|||Cell inner membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/243161:TC_RS03520 ^@ http://purl.uniprot.org/uniprot/Q9PJY1 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS04300 ^@ http://purl.uniprot.org/uniprot/Q9PJI2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS00170 ^@ http://purl.uniprot.org/uniprot/Q9PLR2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/243161:TC_RS03505 ^@ http://purl.uniprot.org/uniprot/Q9PJY4 ^@ Function|||Similarity ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||In the C-terminal section; belongs to the LpxB family. http://togogenome.org/gene/243161:TC_RS04580 ^@ http://purl.uniprot.org/uniprot/Q9PJC7 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/243161:TC_RS00925 ^@ http://purl.uniprot.org/uniprot/Q9PLC3 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/243161:TC_RS04365 ^@ http://purl.uniprot.org/uniprot/Q9PJG9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/243161:TC_RS01805 ^@ http://purl.uniprot.org/uniprot/Q9PKU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the disproportionating enzyme family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS00715 ^@ http://purl.uniprot.org/uniprot/Q9PLG8 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/243161:TC_RS03070 ^@ http://purl.uniprot.org/uniprot/Q9PK65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/243161:TC_RS04675 ^@ http://purl.uniprot.org/uniprot/Q9PJB3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/243161:TC_RS04650 ^@ http://purl.uniprot.org/uniprot/Q9PJB8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/243161:TC_RS03955 ^@ http://purl.uniprot.org/uniprot/Q9PJP8 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/243161:TC_RS02645 ^@ http://purl.uniprot.org/uniprot/Q9PKE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). http://togogenome.org/gene/243161:TC_RS03970 ^@ http://purl.uniprot.org/uniprot/Q9PJP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/243161:TC_RS01025 ^@ http://purl.uniprot.org/uniprot/Q9PLA4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS04205 ^@ http://purl.uniprot.org/uniprot/Q9PJK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03060 ^@ http://purl.uniprot.org/uniprot/Q9PK67 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/243161:TC_RS00435 ^@ http://purl.uniprot.org/uniprot/Q9PLL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/243161:TC_RS03550 ^@ http://purl.uniprot.org/uniprot/P66124 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/243161:TC_RS02425 ^@ http://purl.uniprot.org/uniprot/Q9PKI3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS00660 ^@ http://purl.uniprot.org/uniprot/Q9PLH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/243161:TC_RS01330 ^@ http://purl.uniprot.org/uniprot/Q9PL46 ^@ Developmental Stage|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP outer membrane protein family.|||Cell outer membrane|||Elementary body.|||cell wall http://togogenome.org/gene/243161:TC_RS02980 ^@ http://purl.uniprot.org/uniprot/P56869 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/243161:TC_RS04125 ^@ http://purl.uniprot.org/uniprot/Q9PJL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/243161:TC_RS01020 ^@ http://purl.uniprot.org/uniprot/Q9PLA5 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/243161:TC_RS00915 ^@ http://purl.uniprot.org/uniprot/Q9PLC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03415 ^@ http://purl.uniprot.org/uniprot/Q9PK01 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/243161:TC_RS01855 ^@ http://purl.uniprot.org/uniprot/Q9PKT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/243161:TC_RS00050 ^@ http://purl.uniprot.org/uniprot/Q9PLT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/243161:TC_RS03530 ^@ http://purl.uniprot.org/uniprot/Q9PJY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 9 family.|||Part of an ATP-binding cassette (ABC) transport system involved in metal import (By similarity). Binds a metal with high affinity and specificity and delivers it to the membrane permease for translocation into the cytoplasm (By similarity).|||Periplasm http://togogenome.org/gene/243161:TC_RS01080 ^@ http://purl.uniprot.org/uniprot/Q9PL93 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).|||Tetramer of two alpha and two beta subunits.|||Under complex allosteric control mediated by deoxynucleoside triphosphates and ATP binding. The type of nucleotide bound at the specificity site determines substrate preference. It seems probable that ATP makes the enzyme reduce CDP and UDP, dGTP favors ADP reduction and dTTP favors GDP reduction (By similarity). http://togogenome.org/gene/243161:TC_RS04325 ^@ http://purl.uniprot.org/uniprot/Q9PJH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/243161:TC_RS03260 ^@ http://purl.uniprot.org/uniprot/Q9PK30 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/243161:TC_RS02420 ^@ http://purl.uniprot.org/uniprot/Q9PKI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03410 ^@ http://purl.uniprot.org/uniprot/Q9PK02 ^@ Similarity ^@ Belongs to the chlamydial CPn_0499/CT_392/TC_0671 family. http://togogenome.org/gene/243161:TC_RS04595 ^@ http://purl.uniprot.org/uniprot/P56835 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/243161:TC_RS02800 ^@ http://purl.uniprot.org/uniprot/Q9PKB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/243161:TC_RS04370 ^@ http://purl.uniprot.org/uniprot/Q9PJG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/243161:TC_RS04425 ^@ http://purl.uniprot.org/uniprot/Q9PJF7 ^@ Similarity ^@ Belongs to the UPF0137 (pGP6-D) family. http://togogenome.org/gene/243161:TC_RS02000 ^@ http://purl.uniprot.org/uniprot/Q9PKR2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/243161:TC_RS00535 ^@ http://purl.uniprot.org/uniprot/Q9PLJ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/243161:TC_RS03950 ^@ http://purl.uniprot.org/uniprot/Q9PJP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/243161:TC_RS03105 ^@ http://purl.uniprot.org/uniprot/Q9PK58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/243161:TC_RS03865 ^@ http://purl.uniprot.org/uniprot/Q9PJR8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/243161:TC_RS04445 ^@ http://purl.uniprot.org/uniprot/Q9PJF3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/243161:TC_RS01170 ^@ http://purl.uniprot.org/uniprot/Q9PL76 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/243161:TC_RS02945 ^@ http://purl.uniprot.org/uniprot/Q9PK85 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity). http://togogenome.org/gene/243161:TC_RS00030 ^@ http://purl.uniprot.org/uniprot/Q9PLU0 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/243161:TC_RS02885 ^@ http://purl.uniprot.org/uniprot/Q9PK97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/243161:TC_RS04085 ^@ http://purl.uniprot.org/uniprot/Q9PJM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/243161:TC_RS01980 ^@ http://purl.uniprot.org/uniprot/Q9PKR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). http://togogenome.org/gene/243161:TC_RS04060 ^@ http://purl.uniprot.org/uniprot/P0A4C9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/243161:TC_RS02875 ^@ http://purl.uniprot.org/uniprot/Q9PK99 ^@ Similarity ^@ Belongs to the phosphohexose mutase family.