http://togogenome.org/gene/279238:SARO_RS11530 ^@ http://purl.uniprot.org/uniprot/Q2G5Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS09205 ^@ http://purl.uniprot.org/uniprot/Q2G794 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/279238:SARO_RS08500 ^@ http://purl.uniprot.org/uniprot/Q2G7N7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/279238:SARO_RS15485 ^@ http://purl.uniprot.org/uniprot/Q2G3T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS10575 ^@ http://purl.uniprot.org/uniprot/Q2G6I1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/279238:SARO_RS00120 ^@ http://purl.uniprot.org/uniprot/Q2GCD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/279238:SARO_RS10695 ^@ http://purl.uniprot.org/uniprot/Q2G6F7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/279238:SARO_RS05460 ^@ http://purl.uniprot.org/uniprot/Q2G9D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/279238:SARO_RS11305 ^@ http://purl.uniprot.org/uniprot/Q2G639 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/279238:SARO_RS06710 ^@ http://purl.uniprot.org/uniprot/Q2G8N8 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/279238:SARO_RS09125 ^@ http://purl.uniprot.org/uniprot/Q2G7B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS11550 ^@ http://purl.uniprot.org/uniprot/Q2G5Z2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS17160 ^@ http://purl.uniprot.org/uniprot/A4XDV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS18155 ^@ http://purl.uniprot.org/uniprot/A4XEF5 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/279238:SARO_RS05105 ^@ http://purl.uniprot.org/uniprot/Q2G9K6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/279238:SARO_RS02425 ^@ http://purl.uniprot.org/uniprot/Q2GB42 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/279238:SARO_RS08660 ^@ http://purl.uniprot.org/uniprot/Q2G7K3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/279238:SARO_RS01700 ^@ http://purl.uniprot.org/uniprot/Q2GBI6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/279238:SARO_RS14885 ^@ http://purl.uniprot.org/uniprot/Q2G452 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09840 ^@ http://purl.uniprot.org/uniprot/Q2G6X2 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/279238:SARO_RS07705 ^@ http://purl.uniprot.org/uniprot/Q2G844 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/279238:SARO_RS09115 ^@ http://purl.uniprot.org/uniprot/Q2G7B2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS11055 ^@ http://purl.uniprot.org/uniprot/Q2G687 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/279238:SARO_RS05640 ^@ http://purl.uniprot.org/uniprot/Q2G997 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS16570 ^@ http://purl.uniprot.org/uniprot/Q2G373 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS14125 ^@ http://purl.uniprot.org/uniprot/Q2G4K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09485 ^@ http://purl.uniprot.org/uniprot/Q2G739 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/279238:SARO_RS01925 ^@ http://purl.uniprot.org/uniprot/Q2GBE0 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/279238:SARO_RS08930 ^@ http://purl.uniprot.org/uniprot/Q2G7E9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS05065 ^@ http://purl.uniprot.org/uniprot/Q2G9L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/279238:SARO_RS13155 ^@ http://purl.uniprot.org/uniprot/Q2G528 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/279238:SARO_RS19980 ^@ http://purl.uniprot.org/uniprot/A4XFG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aromatic amine dehydrogenase light chain family.|||Heterotetramer of two light and two heavy chains.|||Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.|||Periplasm http://togogenome.org/gene/279238:SARO_RS11505 ^@ http://purl.uniprot.org/uniprot/Q2G601 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS13570 ^@ http://purl.uniprot.org/uniprot/Q2G4W4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS05850 ^@ http://purl.uniprot.org/uniprot/Q2G955 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/279238:SARO_RS09085 ^@ http://purl.uniprot.org/uniprot/Q2G7B8 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/279238:SARO_RS13460 ^@ http://purl.uniprot.org/uniprot/Q2G4Y6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/279238:SARO_RS06510 ^@ http://purl.uniprot.org/uniprot/Q2G8S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/279238:SARO_RS18765 ^@ http://purl.uniprot.org/uniprot/A4XES7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS11515 ^@ http://purl.uniprot.org/uniprot/Q2G5Z9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS15740 ^@ http://purl.uniprot.org/uniprot/Q2G3N9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/279238:SARO_RS05700 ^@ http://purl.uniprot.org/uniprot/Q2G985 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS00985 ^@ http://purl.uniprot.org/uniprot/Q2GBX7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/279238:SARO_RS11485 ^@ http://purl.uniprot.org/uniprot/Q2G605 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/279238:SARO_RS06910 ^@ http://purl.uniprot.org/uniprot/Q2G8K1 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/279238:SARO_RS10535 ^@ http://purl.uniprot.org/uniprot/Q2G6J0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS18500 ^@ http://purl.uniprot.org/uniprot/A4XEM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08390 ^@ http://purl.uniprot.org/uniprot/Q2G7Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS10210 ^@ http://purl.uniprot.org/uniprot/Q2G6Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08070 ^@ http://purl.uniprot.org/uniprot/Q2G7X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS16430 ^@ http://purl.uniprot.org/uniprot/Q2G3A2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/279238:SARO_RS03500 ^@ http://purl.uniprot.org/uniprot/Q2GAH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/279238:SARO_RS18475 ^@ http://purl.uniprot.org/uniprot/A4XEL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS03705 ^@ http://purl.uniprot.org/uniprot/Q2GAD5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/279238:SARO_RS15750 ^@ http://purl.uniprot.org/uniprot/Q2G3N7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/279238:SARO_RS10875 ^@ http://purl.uniprot.org/uniprot/Q2G6C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/279238:SARO_RS07045 ^@ http://purl.uniprot.org/uniprot/Q2G8H4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/279238:SARO_RS03715 ^@ http://purl.uniprot.org/uniprot/Q2GAD3 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS11980 ^@ http://purl.uniprot.org/uniprot/Q2G5Q6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS00975 ^@ http://purl.uniprot.org/uniprot/Q2GBX9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/279238:SARO_RS13430 ^@ http://purl.uniprot.org/uniprot/Q2G4Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/279238:SARO_RS03515 ^@ http://purl.uniprot.org/uniprot/Q2GAH3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS00655 ^@ http://purl.uniprot.org/uniprot/Q2GC42 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01940 ^@ http://purl.uniprot.org/uniprot/Q2GBD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/279238:SARO_RS09320 ^@ http://purl.uniprot.org/uniprot/Q2G772 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/279238:SARO_RS04475 ^@ http://purl.uniprot.org/uniprot/Q2G9Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS14590 ^@ http://purl.uniprot.org/uniprot/Q2G4B0 ^@ Similarity ^@ Belongs to the UPF0311 family. http://togogenome.org/gene/279238:SARO_RS16390 ^@ http://purl.uniprot.org/uniprot/Q2G3B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/279238:SARO_RS05220 ^@ http://purl.uniprot.org/uniprot/Q2G9I1 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/279238:SARO_RS08835 ^@ http://purl.uniprot.org/uniprot/Q2G7G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/279238:SARO_RS14130 ^@ http://purl.uniprot.org/uniprot/Q2G4K2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/279238:SARO_RS18990 ^@ http://purl.uniprot.org/uniprot/A4XEX1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS06380 ^@ http://purl.uniprot.org/uniprot/Q2G8V4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS18240 ^@ http://purl.uniprot.org/uniprot/A4XEH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS18660 ^@ http://purl.uniprot.org/uniprot/A4XEQ6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06345 ^@ http://purl.uniprot.org/uniprot/Q2G8W1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS17015 ^@ http://purl.uniprot.org/uniprot/A4XDS7 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/279238:SARO_RS01395 ^@ http://purl.uniprot.org/uniprot/Q2GBP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/279238:SARO_RS18710 ^@ http://purl.uniprot.org/uniprot/A4XER6 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/279238:SARO_RS11150 ^@ http://purl.uniprot.org/uniprot/Q2G669 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/279238:SARO_RS10020 ^@ http://purl.uniprot.org/uniprot/Q2G6U1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/279238:SARO_RS07770 ^@ http://purl.uniprot.org/uniprot/Q2G832 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/279238:SARO_RS16440 ^@ http://purl.uniprot.org/uniprot/Q2G3A0 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/279238:SARO_RS09930 ^@ http://purl.uniprot.org/uniprot/Q2G6V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS01670 ^@ http://purl.uniprot.org/uniprot/Q2GBJ2 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/279238:SARO_RS03100 ^@ http://purl.uniprot.org/uniprot/Q2GAQ6 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/279238:SARO_RS06285 ^@ http://purl.uniprot.org/uniprot/Q2G8X3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS08980 ^@ http://purl.uniprot.org/uniprot/Q2G7D9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/279238:SARO_RS12145 ^@ http://purl.uniprot.org/uniprot/Q2G5M3 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/279238:SARO_RS06135 ^@ http://purl.uniprot.org/uniprot/Q2G901 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS00585 ^@ http://purl.uniprot.org/uniprot/Q2GC57 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/279238:SARO_RS19835 ^@ http://purl.uniprot.org/uniprot/A4XFE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06620 ^@ http://purl.uniprot.org/uniprot/Q2G8Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS02700 ^@ http://purl.uniprot.org/uniprot/Q2GAY4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/279238:SARO_RS06780 ^@ http://purl.uniprot.org/uniprot/Q2G8M6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/279238:SARO_RS05655 ^@ http://purl.uniprot.org/uniprot/Q2G994 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09010 ^@ http://purl.uniprot.org/uniprot/Q2G7D3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/279238:SARO_RS05650 ^@ http://purl.uniprot.org/uniprot/Q2G995 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/279238:SARO_RS04415 ^@ http://purl.uniprot.org/uniprot/Q2G9Z6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinylarginine dihydrolase family.|||Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS12560 ^@ http://purl.uniprot.org/uniprot/Q2G5E1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/279238:SARO_RS01345 ^@ http://purl.uniprot.org/uniprot/Q2GBQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS16810 ^@ http://purl.uniprot.org/uniprot/Q2G328 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/279238:SARO_RS14170 ^@ http://purl.uniprot.org/uniprot/Q2G4J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/279238:SARO_RS14370 ^@ http://purl.uniprot.org/uniprot/Q2G4F4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/279238:SARO_RS02275 ^@ http://purl.uniprot.org/uniprot/Q2GB71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS12370 ^@ http://purl.uniprot.org/uniprot/Q2G5H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS12285 ^@ http://purl.uniprot.org/uniprot/Q2G5J6 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/279238:SARO_RS03435 ^@ http://purl.uniprot.org/uniprot/Q2GAI8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/279238:SARO_RS16565 ^@ http://purl.uniprot.org/uniprot/Q2G374 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/279238:SARO_RS04595 ^@ http://purl.uniprot.org/uniprot/Q2G9V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS10255 ^@ http://purl.uniprot.org/uniprot/Q2G6P5 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/279238:SARO_RS04155 ^@ http://purl.uniprot.org/uniprot/Q2GA47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/279238:SARO_RS05060 ^@ http://purl.uniprot.org/uniprot/Q2G9L5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/279238:SARO_RS06480 ^@ http://purl.uniprot.org/uniprot/Q2G8T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18985 ^@ http://purl.uniprot.org/uniprot/A4XEX0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS05665 ^@ http://purl.uniprot.org/uniprot/Q2G992 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS06920 ^@ http://purl.uniprot.org/uniprot/Q2G8J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS01470 ^@ http://purl.uniprot.org/uniprot/Q2GBN2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/279238:SARO_RS14875 ^@ http://purl.uniprot.org/uniprot/Q2G454 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS06580 ^@ http://purl.uniprot.org/uniprot/Q2G8R4 ^@ Function|||Similarity ^@ A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.|||Belongs to the bacterial AtpI family. http://togogenome.org/gene/279238:SARO_RS00265 ^@ http://purl.uniprot.org/uniprot/Q2GCC1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS02900 ^@ http://purl.uniprot.org/uniprot/Q2GAU5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS06950 ^@ http://purl.uniprot.org/uniprot/Q2G8J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS05675 ^@ http://purl.uniprot.org/uniprot/Q2G990 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/279238:SARO_RS03060 ^@ http://purl.uniprot.org/uniprot/Q2GAR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06225 ^@ http://purl.uniprot.org/uniprot/Q2G8Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/279238:SARO_RS11325 ^@ http://purl.uniprot.org/uniprot/Q2G635 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/279238:SARO_RS01630 ^@ http://purl.uniprot.org/uniprot/Q2GBK0 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/279238:SARO_RS16350 ^@ http://purl.uniprot.org/uniprot/Q2G3B8 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS07635 ^@ http://purl.uniprot.org/uniprot/Q2G859 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS01665 ^@ http://purl.uniprot.org/uniprot/Q2GBJ3 ^@ Function ^@ Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. http://togogenome.org/gene/279238:SARO_RS05490 ^@ http://purl.uniprot.org/uniprot/Q2G9C8 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/279238:SARO_RS04555 ^@ http://purl.uniprot.org/uniprot/Q2G9W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/279238:SARO_RS10610 ^@ http://purl.uniprot.org/uniprot/Q2G6H4 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the reversible phosphorylation of pyruvate and phosphate. http://togogenome.org/gene/279238:SARO_RS08450 ^@ http://purl.uniprot.org/uniprot/Q2G7P7 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/279238:SARO_RS00080 ^@ http://purl.uniprot.org/uniprot/Q2GCE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/279238:SARO_RS19830 ^@ http://purl.uniprot.org/uniprot/A4XFD9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS14310 ^@ http://purl.uniprot.org/uniprot/Q2G4G6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/279238:SARO_RS15460 ^@ http://purl.uniprot.org/uniprot/Q2G3U1 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/279238:SARO_RS19090 ^@ http://purl.uniprot.org/uniprot/A4XEZ1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS02850 ^@ http://purl.uniprot.org/uniprot/Q2GAV5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/279238:SARO_RS19310 ^@ http://purl.uniprot.org/uniprot/A4XF36 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS17130 ^@ http://purl.uniprot.org/uniprot/A4XDU9 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/279238:SARO_RS05145 ^@ http://purl.uniprot.org/uniprot/Q2G9J6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/279238:SARO_RS04455 ^@ http://purl.uniprot.org/uniprot/Q2G9Y8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/279238:SARO_RS01800 ^@ http://purl.uniprot.org/uniprot/Q2GBG5 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/279238:SARO_RS20260 ^@ http://purl.uniprot.org/uniprot/Q2G5G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18675 ^@ http://purl.uniprot.org/uniprot/A4XEQ9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS05970 ^@ http://purl.uniprot.org/uniprot/Q2G933 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS03630 ^@ http://purl.uniprot.org/uniprot/Q2GAF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS04260 ^@ http://purl.uniprot.org/uniprot/Q2GA26 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/279238:SARO_RS01540 ^@ http://purl.uniprot.org/uniprot/Q2GBL8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS13030 ^@ http://purl.uniprot.org/uniprot/Q2G552 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/279238:SARO_RS11580 ^@ http://purl.uniprot.org/uniprot/Q2G5Y6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS05470 ^@ http://purl.uniprot.org/uniprot/Q2G9D2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/279238:SARO_RS12040 ^@ http://purl.uniprot.org/uniprot/Q2G5P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/279238:SARO_RS05370 ^@ http://purl.uniprot.org/uniprot/Q2G9F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06240 ^@ http://purl.uniprot.org/uniprot/Q2G8Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/279238:SARO_RS03385 ^@ http://purl.uniprot.org/uniprot/Q2GAJ8 ^@ Cofactor|||Function|||Miscellaneous|||Subcellular Location Annotation|||Subunit ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/279238:SARO_RS10705 ^@ http://purl.uniprot.org/uniprot/Q2G6F5 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/279238:SARO_RS04340 ^@ http://purl.uniprot.org/uniprot/Q2GA11 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS00470 ^@ http://purl.uniprot.org/uniprot/Q2GC80 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/279238:SARO_RS13120 ^@ http://purl.uniprot.org/uniprot/Q2G535 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS13625 ^@ http://purl.uniprot.org/uniprot/Q2G4V3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/279238:SARO_RS18515 ^@ http://purl.uniprot.org/uniprot/A4XEM7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS12335 ^@ http://purl.uniprot.org/uniprot/Q2G5I6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS02840 ^@ http://purl.uniprot.org/uniprot/Q2GAV7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS07100 ^@ http://purl.uniprot.org/uniprot/Q2G8G3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/279238:SARO_RS04640 ^@ http://purl.uniprot.org/uniprot/Q2G9U9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/279238:SARO_RS08855 ^@ http://purl.uniprot.org/uniprot/Q2G7G4 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/279238:SARO_RS10425 ^@ http://purl.uniprot.org/uniprot/Q2G6L1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/279238:SARO_RS01625 ^@ http://purl.uniprot.org/uniprot/Q2GBK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/279238:SARO_RS01425 ^@ http://purl.uniprot.org/uniprot/Q2GBP1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/279238:SARO_RS04850 ^@ http://purl.uniprot.org/uniprot/Q2G9Q7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/279238:SARO_RS08600 ^@ http://purl.uniprot.org/uniprot/Q2G7L5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS16695 ^@ http://purl.uniprot.org/uniprot/Q2G350 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COX15/CtaA family. Type 2 subfamily.|||Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.|||Cell membrane|||Interacts with CtaB. http://togogenome.org/gene/279238:SARO_RS05925 ^@ http://purl.uniprot.org/uniprot/Q2G940 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/279238:SARO_RS02435 ^@ http://purl.uniprot.org/uniprot/Q2GB40 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/279238:SARO_RS13240 ^@ http://purl.uniprot.org/uniprot/Q2G512 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/279238:SARO_RS09915 ^@ http://purl.uniprot.org/uniprot/Q2G6V9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06945 ^@ http://purl.uniprot.org/uniprot/Q2G8J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP J family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS13005 ^@ http://purl.uniprot.org/uniprot/Q2G557 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06585 ^@ http://purl.uniprot.org/uniprot/Q2G8R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/279238:SARO_RS04400 ^@ http://purl.uniprot.org/uniprot/Q2G9Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16655 ^@ http://purl.uniprot.org/uniprot/Q2G358 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS09855 ^@ http://purl.uniprot.org/uniprot/Q2G6W9 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/279238:SARO_RS00150 ^@ http://purl.uniprot.org/uniprot/Q2GCD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/279238:SARO_RS00885 ^@ http://purl.uniprot.org/uniprot/Q2GBZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS03470 ^@ http://purl.uniprot.org/uniprot/Q2GAI1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS02660 ^@ http://purl.uniprot.org/uniprot/Q2GAZ2 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/279238:SARO_RS10325 ^@ http://purl.uniprot.org/uniprot/Q2G6N1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/279238:SARO_RS00095 ^@ http://purl.uniprot.org/uniprot/Q2GCE2 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01120 ^@ http://purl.uniprot.org/uniprot/Q2GBV1 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/279238:SARO_RS18060 ^@ http://purl.uniprot.org/uniprot/A4XED6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06615 ^@ http://purl.uniprot.org/uniprot/Q2G8Q7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/279238:SARO_RS06300 ^@ http://purl.uniprot.org/uniprot/Q2G8X0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/279238:SARO_RS05280 ^@ http://purl.uniprot.org/uniprot/Q2G9H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/279238:SARO_RS14195 ^@ http://purl.uniprot.org/uniprot/Q2G4I9 ^@ Function ^@ Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/279238:SARO_RS04900 ^@ http://purl.uniprot.org/uniprot/Q2G9P7 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/279238:SARO_RS09065 ^@ http://purl.uniprot.org/uniprot/Q2G7C2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS00230 ^@ http://purl.uniprot.org/uniprot/Q2G2Y8 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/279238:SARO_RS10615 ^@ http://purl.uniprot.org/uniprot/Q2G6H3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/279238:SARO_RS11905 ^@ http://purl.uniprot.org/uniprot/Q2G5S1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/279238:SARO_RS08830 ^@ http://purl.uniprot.org/uniprot/Q2G7G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS02685 ^@ http://purl.uniprot.org/uniprot/Q2GAY7 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS13435 ^@ http://purl.uniprot.org/uniprot/Q2G4Z1 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/279238:SARO_RS06245 ^@ http://purl.uniprot.org/uniprot/Q2G8Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS09845 ^@ http://purl.uniprot.org/uniprot/Q2G6X1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS15710 ^@ http://purl.uniprot.org/uniprot/Q2G3P5 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/279238:SARO_RS11670 ^@ http://purl.uniprot.org/uniprot/Q2G5W8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.|||Homotetramer formed by a dimer of dimers. http://togogenome.org/gene/279238:SARO_RS14085 ^@ http://purl.uniprot.org/uniprot/Q2G4L1 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS18780 ^@ http://purl.uniprot.org/uniprot/A4XET0 ^@ Similarity ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. http://togogenome.org/gene/279238:SARO_RS09165 ^@ http://purl.uniprot.org/uniprot/Q2G7A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS02495 ^@ http://purl.uniprot.org/uniprot/Q2GB27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/279238:SARO_RS16940 ^@ http://purl.uniprot.org/uniprot/Q2G302 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS07825 ^@ http://purl.uniprot.org/uniprot/Q2G821 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS13515 ^@ http://purl.uniprot.org/uniprot/Q2G4X5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS09615 ^@ http://purl.uniprot.org/uniprot/Q2G715 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/279238:SARO_RS09550 ^@ http://purl.uniprot.org/uniprot/Q2G726 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/279238:SARO_RS10780 ^@ http://purl.uniprot.org/uniprot/Q2G6E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS15495 ^@ http://purl.uniprot.org/uniprot/Q2G3T4 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/279238:SARO_RS16710 ^@ http://purl.uniprot.org/uniprot/Q2G347 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/279238:SARO_RS04040 ^@ http://purl.uniprot.org/uniprot/Q2GA69 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS00175 ^@ http://purl.uniprot.org/uniprot/Q2G2Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/279238:SARO_RS14650 ^@ http://purl.uniprot.org/uniprot/Q2G498 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/279238:SARO_RS11910 ^@ http://purl.uniprot.org/uniprot/Q2G5S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/279238:SARO_RS19595 ^@ http://purl.uniprot.org/uniprot/A4XF92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS05635 ^@ http://purl.uniprot.org/uniprot/Q2G998 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane http://togogenome.org/gene/279238:SARO_RS10215 ^@ http://purl.uniprot.org/uniprot/Q2G6Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS12555 ^@ http://purl.uniprot.org/uniprot/Q2G5E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS19490 ^@ http://purl.uniprot.org/uniprot/A4XF71 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06410 ^@ http://purl.uniprot.org/uniprot/Q2G8U7 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/279238:SARO_RS11060 ^@ http://purl.uniprot.org/uniprot/Q2G686 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/279238:SARO_RS09730 ^@ http://purl.uniprot.org/uniprot/Q2G6Z2 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/279238:SARO_RS00880 ^@ http://purl.uniprot.org/uniprot/Q2GBZ7 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/279238:SARO_RS20345 ^@ http://purl.uniprot.org/uniprot/Q2G3M3 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/279238:SARO_RS13485 ^@ http://purl.uniprot.org/uniprot/Q2G4Y1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/279238:SARO_RS08430 ^@ http://purl.uniprot.org/uniprot/Q2G7Q1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/279238:SARO_RS00255 ^@ http://purl.uniprot.org/uniprot/Q2GCC3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/279238:SARO_RS06880 ^@ http://purl.uniprot.org/uniprot/Q2G8K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/279238:SARO_RS06085 ^@ http://purl.uniprot.org/uniprot/Q2G911 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/279238:SARO_RS16525 ^@ http://purl.uniprot.org/uniprot/Q2G382 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/279238:SARO_RS04995 ^@ http://purl.uniprot.org/uniprot/Q2G9M8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS03585 ^@ http://purl.uniprot.org/uniprot/Q2GAF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS14785 ^@ http://purl.uniprot.org/uniprot/Q2G472 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS18800 ^@ http://purl.uniprot.org/uniprot/A4XET4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/279238:SARO_RS14745 ^@ http://purl.uniprot.org/uniprot/Q2G480 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/279238:SARO_RS08480 ^@ http://purl.uniprot.org/uniprot/Q2G7P1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS05980 ^@ http://purl.uniprot.org/uniprot/Q2G931 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS10800 ^@ http://purl.uniprot.org/uniprot/Q2G6D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS01020 ^@ http://purl.uniprot.org/uniprot/Q2GBX1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS07570 ^@ http://purl.uniprot.org/uniprot/Q2G871 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS17890 ^@ http://purl.uniprot.org/uniprot/A4XEA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS10670 ^@ http://purl.uniprot.org/uniprot/Q2G6G2 ^@ Function ^@ Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site. http://togogenome.org/gene/279238:SARO_RS14315 ^@ http://purl.uniprot.org/uniprot/Q2G4G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/279238:SARO_RS08915 ^@ http://purl.uniprot.org/uniprot/Q2G7F2 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/279238:SARO_RS10175 ^@ http://purl.uniprot.org/uniprot/Q2G6R1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS00240 ^@ http://purl.uniprot.org/uniprot/Q2GCC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS09135 ^@ http://purl.uniprot.org/uniprot/Q2G7A8 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/279238:SARO_RS06870 ^@ http://purl.uniprot.org/uniprot/Q2G8K9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS02105 ^@ http://purl.uniprot.org/uniprot/Q2GBA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/279238:SARO_RS06310 ^@ http://purl.uniprot.org/uniprot/Q2G8W8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/279238:SARO_RS17280 ^@ http://purl.uniprot.org/uniprot/A4XDX7 ^@ Function|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. http://togogenome.org/gene/279238:SARO_RS16205 ^@ http://purl.uniprot.org/uniprot/Q2G3E7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS12725 ^@ http://purl.uniprot.org/uniprot/Q2G5B0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/279238:SARO_RS08035 ^@ http://purl.uniprot.org/uniprot/Q2G7Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00420 ^@ http://purl.uniprot.org/uniprot/Q2GC90 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/279238:SARO_RS07405 ^@ http://purl.uniprot.org/uniprot/Q2G8A4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS03925 ^@ http://purl.uniprot.org/uniprot/Q2GA91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS19675 ^@ http://purl.uniprot.org/uniprot/A4XFA8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS12220 ^@ http://purl.uniprot.org/uniprot/Q2G5K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS13375 ^@ http://purl.uniprot.org/uniprot/Q2G503 ^@ Similarity ^@ Belongs to the ClpX chaperone family. HslU subfamily. http://togogenome.org/gene/279238:SARO_RS14475 ^@ http://purl.uniprot.org/uniprot/Q2G4D3 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/279238:SARO_RS08475 ^@ http://purl.uniprot.org/uniprot/Q2G7P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS20025 ^@ http://purl.uniprot.org/uniprot/A4XFH8 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/279238:SARO_RS06315 ^@ http://purl.uniprot.org/uniprot/Q2G8W7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/279238:SARO_RS05045 ^@ http://purl.uniprot.org/uniprot/Q2G9L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/279238:SARO_RS14385 ^@ http://purl.uniprot.org/uniprot/Q2G4F1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/279238:SARO_RS02110 ^@ http://purl.uniprot.org/uniprot/Q2GBA3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/279238:SARO_RS10775 ^@ http://purl.uniprot.org/uniprot/Q2G6E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS04920 ^@ http://purl.uniprot.org/uniprot/Q2G9P3 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/279238:SARO_RS06990 ^@ http://purl.uniprot.org/uniprot/Q2G8I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell inner membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/279238:SARO_RS04450 ^@ http://purl.uniprot.org/uniprot/Q2G9Y9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS13230 ^@ http://purl.uniprot.org/uniprot/Q2G514 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18775 ^@ http://purl.uniprot.org/uniprot/A4XES9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit.|||Catalyzes the conversion of 8'-apo-beta-carotenal to 13-apo-beta-carotenone and C12-dialdehyde. Has also weak activity with 4'-apo-beta-carotenal and gamma-carotene.|||Monomer. http://togogenome.org/gene/279238:SARO_RS00935 ^@ http://purl.uniprot.org/uniprot/Q2GBY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS14930 ^@ http://purl.uniprot.org/uniprot/Q2G443 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/279238:SARO_RS08775 ^@ http://purl.uniprot.org/uniprot/Q2G7I0 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS09860 ^@ http://purl.uniprot.org/uniprot/Q2G6W8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS02035 ^@ http://purl.uniprot.org/uniprot/Q2GBB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/279238:SARO_RS01050 ^@ http://purl.uniprot.org/uniprot/Q2GBW5 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/279238:SARO_RS06705 ^@ http://purl.uniprot.org/uniprot/Q2G8N9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/279238:SARO_RS05050 ^@ http://purl.uniprot.org/uniprot/Q2G9L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS15590 ^@ http://purl.uniprot.org/uniprot/Q2G3R8 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/279238:SARO_RS05040 ^@ http://purl.uniprot.org/uniprot/Q2G9L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS13080 ^@ http://purl.uniprot.org/uniprot/Q2G542 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/279238:SARO_RS04005 ^@ http://purl.uniprot.org/uniprot/Q2GA76 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/279238:SARO_RS10160 ^@ http://purl.uniprot.org/uniprot/Q2G6R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS01605 ^@ http://purl.uniprot.org/uniprot/Q2GBK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/279238:SARO_RS02485 ^@ http://purl.uniprot.org/uniprot/Q2GB29 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS16605 ^@ http://purl.uniprot.org/uniprot/Q2G368 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/279238:SARO_RS09095 ^@ http://purl.uniprot.org/uniprot/Q2G7B6 ^@ Similarity ^@ Belongs to the lycopene cyclase family. http://togogenome.org/gene/279238:SARO_RS02790 ^@ http://purl.uniprot.org/uniprot/Q2GAW7 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/279238:SARO_RS02040 ^@ http://purl.uniprot.org/uniprot/Q2GBB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00170 ^@ http://purl.uniprot.org/uniprot/Q2GCC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/279238:SARO_RS09810 ^@ http://purl.uniprot.org/uniprot/Q2G6X7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/279238:SARO_RS04560 ^@ http://purl.uniprot.org/uniprot/Q2G9W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS06630 ^@ http://purl.uniprot.org/uniprot/Q2G8Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS12995 ^@ http://purl.uniprot.org/uniprot/Q2G559 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/279238:SARO_RS16560 ^@ http://purl.uniprot.org/uniprot/Q2G375 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS16630 ^@ http://purl.uniprot.org/uniprot/Q2G363 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS11625 ^@ http://purl.uniprot.org/uniprot/Q2G5X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS04440 ^@ http://purl.uniprot.org/uniprot/Q2G9Z1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is located at the dimer interface. http://togogenome.org/gene/279238:SARO_RS17320 ^@ http://purl.uniprot.org/uniprot/A4XDY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS09650 ^@ http://purl.uniprot.org/uniprot/Q2G708 ^@ Function|||Similarity ^@ Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. http://togogenome.org/gene/279238:SARO_RS10495 ^@ http://purl.uniprot.org/uniprot/Q2G6J8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/279238:SARO_RS18115 ^@ http://purl.uniprot.org/uniprot/A4XEE7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS07240 ^@ http://purl.uniprot.org/uniprot/Q2G8D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/279238:SARO_RS21370 ^@ http://purl.uniprot.org/uniprot/Q2G441 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/279238:SARO_RS12505 ^@ http://purl.uniprot.org/uniprot/Q2G5F3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/279238:SARO_RS11830 ^@ http://purl.uniprot.org/uniprot/Q2G5T5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/279238:SARO_RS10330 ^@ http://purl.uniprot.org/uniprot/Q2G6N0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/279238:SARO_RS02070 ^@ http://purl.uniprot.org/uniprot/Q2GBB1 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/279238:SARO_RS18100 ^@ http://purl.uniprot.org/uniprot/A4XEE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS04370 ^@ http://purl.uniprot.org/uniprot/Q2GA05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS15985 ^@ http://purl.uniprot.org/uniprot/Q2G3J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS04220 ^@ http://purl.uniprot.org/uniprot/Q2GA34 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/279238:SARO_RS17265 ^@ http://purl.uniprot.org/uniprot/A4XDX4 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/279238:SARO_RS12545 ^@ http://purl.uniprot.org/uniprot/Q2G5E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/279238:SARO_RS19575 ^@ http://purl.uniprot.org/uniprot/A4XF88 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/279238:SARO_RS09295 ^@ http://purl.uniprot.org/uniprot/Q2G777 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/279238:SARO_RS09490 ^@ http://purl.uniprot.org/uniprot/Q2G738 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/279238:SARO_RS05570 ^@ http://purl.uniprot.org/uniprot/Q2G9B1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS19680 ^@ http://purl.uniprot.org/uniprot/A4XFA9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS16370 ^@ http://purl.uniprot.org/uniprot/Q2G3B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00570 ^@ http://purl.uniprot.org/uniprot/Q2GC60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS19280 ^@ http://purl.uniprot.org/uniprot/A4XF30 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS16285 ^@ http://purl.uniprot.org/uniprot/Q2G3D0 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/279238:SARO_RS11660 ^@ http://purl.uniprot.org/uniprot/Q2G5X0 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/279238:SARO_RS01110 ^@ http://purl.uniprot.org/uniprot/Q2GBV3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/279238:SARO_RS17880 ^@ http://purl.uniprot.org/uniprot/A4XEA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS16685 ^@ http://purl.uniprot.org/uniprot/Q2G352 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/279238:SARO_RS11400 ^@ http://purl.uniprot.org/uniprot/Q2G620 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/279238:SARO_RS11480 ^@ http://purl.uniprot.org/uniprot/Q2G606 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/279238:SARO_RS01385 ^@ http://purl.uniprot.org/uniprot/Q2GBP9 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/279238:SARO_RS04165 ^@ http://purl.uniprot.org/uniprot/Q2GA45 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/279238:SARO_RS07150 ^@ http://purl.uniprot.org/uniprot/Q2G8F3 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/279238:SARO_RS07510 ^@ http://purl.uniprot.org/uniprot/Q2G884 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS03785 ^@ http://purl.uniprot.org/uniprot/Q2GAB9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS08545 ^@ http://purl.uniprot.org/uniprot/Q2G7M8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS05275 ^@ http://purl.uniprot.org/uniprot/Q2G9H1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/279238:SARO_RS05100 ^@ http://purl.uniprot.org/uniprot/Q2G9K7 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/279238:SARO_RS11650 ^@ http://purl.uniprot.org/uniprot/Q2G5X2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/279238:SARO_RS02745 ^@ http://purl.uniprot.org/uniprot/Q2GAX5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/279238:SARO_RS09760 ^@ http://purl.uniprot.org/uniprot/Q2G6Y7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/279238:SARO_RS04295 ^@ http://purl.uniprot.org/uniprot/Q2GA20 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01615 ^@ http://purl.uniprot.org/uniprot/Q2GBK3 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/279238:SARO_RS07070 ^@ http://purl.uniprot.org/uniprot/Q2G8G9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS13525 ^@ http://purl.uniprot.org/uniprot/Q2G4X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/279238:SARO_RS05025 ^@ http://purl.uniprot.org/uniprot/Q2G9M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09870 ^@ http://purl.uniprot.org/uniprot/Q2G6W6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00755 ^@ http://purl.uniprot.org/uniprot/Q2GC22 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/279238:SARO_RS12605 ^@ http://purl.uniprot.org/uniprot/Q2G5D4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09040 ^@ http://purl.uniprot.org/uniprot/Q2G7C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS06230 ^@ http://purl.uniprot.org/uniprot/Q2G8Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/279238:SARO_RS05150 ^@ http://purl.uniprot.org/uniprot/Q2G9J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/279238:SARO_RS09495 ^@ http://purl.uniprot.org/uniprot/Q2G737 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09780 ^@ http://purl.uniprot.org/uniprot/Q2G6Y3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS14515 ^@ http://purl.uniprot.org/uniprot/Q2G4C5 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/279238:SARO_RS03665 ^@ http://purl.uniprot.org/uniprot/Q2GAE3 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/279238:SARO_RS02005 ^@ http://purl.uniprot.org/uniprot/Q2GBC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18810 ^@ http://purl.uniprot.org/uniprot/A4XET6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS11245 ^@ http://purl.uniprot.org/uniprot/Q2G651 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/279238:SARO_RS06980 ^@ http://purl.uniprot.org/uniprot/Q2G8I7 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/279238:SARO_RS12135 ^@ http://purl.uniprot.org/uniprot/Q2G5M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS12495 ^@ http://purl.uniprot.org/uniprot/Q2G5F5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/279238:SARO_RS18490 ^@ http://purl.uniprot.org/uniprot/A4XEM2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/279238:SARO_RS02985 ^@ http://purl.uniprot.org/uniprot/Q2GAS7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS12945 ^@ http://purl.uniprot.org/uniprot/Q2G569 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/279238:SARO_RS07910 ^@ http://purl.uniprot.org/uniprot/Q2G804 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/279238:SARO_RS17235 ^@ http://purl.uniprot.org/uniprot/A4XDW8 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/279238:SARO_RS11525 ^@ http://purl.uniprot.org/uniprot/Q2G5Z7 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/279238:SARO_RS16775 ^@ http://purl.uniprot.org/uniprot/Q2G335 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/279238:SARO_RS05415 ^@ http://purl.uniprot.org/uniprot/Q2G9E3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/279238:SARO_RS00600 ^@ http://purl.uniprot.org/uniprot/Q2GC54 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS10360 ^@ http://purl.uniprot.org/uniprot/Q2G6M4 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/279238:SARO_RS14915 ^@ http://purl.uniprot.org/uniprot/Q2G446 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/279238:SARO_RS18110 ^@ http://purl.uniprot.org/uniprot/A4XEE6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS03190 ^@ http://purl.uniprot.org/uniprot/Q2GAN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/279238:SARO_RS04980 ^@ http://purl.uniprot.org/uniprot/Q2G9N1 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/279238:SARO_RS18460 ^@ http://purl.uniprot.org/uniprot/A4XEL6 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/279238:SARO_RS16275 ^@ http://purl.uniprot.org/uniprot/Q2G3D2 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/279238:SARO_RS10370 ^@ http://purl.uniprot.org/uniprot/Q2G6M2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/279238:SARO_RS17170 ^@ http://purl.uniprot.org/uniprot/A4XDV7 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS08360 ^@ http://purl.uniprot.org/uniprot/Q2G7R5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS02310 ^@ http://purl.uniprot.org/uniprot/Q2GB64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS00030 ^@ http://purl.uniprot.org/uniprot/Q2GCF5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/279238:SARO_RS13380 ^@ http://purl.uniprot.org/uniprot/Q2G502 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/279238:SARO_RS12690 ^@ http://purl.uniprot.org/uniprot/Q2G5B7 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/279238:SARO_RS02010 ^@ http://purl.uniprot.org/uniprot/Q2GBC3 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/279238:SARO_RS04435 ^@ http://purl.uniprot.org/uniprot/Q2G9Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/279238:SARO_RS10180 ^@ http://purl.uniprot.org/uniprot/Q2G6R0 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/279238:SARO_RS16190 ^@ http://purl.uniprot.org/uniprot/Q2G3F0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/279238:SARO_RS04570 ^@ http://purl.uniprot.org/uniprot/Q2G9W4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/279238:SARO_RS14445 ^@ http://purl.uniprot.org/uniprot/Q2G4D9 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/279238:SARO_RS05755 ^@ http://purl.uniprot.org/uniprot/Q2G975 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/279238:SARO_RS12090 ^@ http://purl.uniprot.org/uniprot/Q2G5N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/279238:SARO_RS12625 ^@ http://purl.uniprot.org/uniprot/Q2G5D0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS18220 ^@ http://purl.uniprot.org/uniprot/A4XEG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08900 ^@ http://purl.uniprot.org/uniprot/Q2G7F5 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/279238:SARO_RS19275 ^@ http://purl.uniprot.org/uniprot/A4XF28 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS12910 ^@ http://purl.uniprot.org/uniprot/Q2G576 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS02755 ^@ http://purl.uniprot.org/uniprot/Q2GAX3 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/279238:SARO_RS17930 ^@ http://purl.uniprot.org/uniprot/A4XEB0 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/279238:SARO_RS11225 ^@ http://purl.uniprot.org/uniprot/Q2G654 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/279238:SARO_RS09265 ^@ http://purl.uniprot.org/uniprot/Q2G782 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/279238:SARO_RS11520 ^@ http://purl.uniprot.org/uniprot/Q2G5Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS14920 ^@ http://purl.uniprot.org/uniprot/Q2G445 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/279238:SARO_RS00710 ^@ http://purl.uniprot.org/uniprot/Q2GC31 ^@ Similarity ^@ Belongs to the UPF0262 family. http://togogenome.org/gene/279238:SARO_RS17380 ^@ http://purl.uniprot.org/uniprot/A4XDZ9 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/279238:SARO_RS17070 ^@ http://purl.uniprot.org/uniprot/A4XDT7 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS16480 ^@ http://purl.uniprot.org/uniprot/Q2G391 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/279238:SARO_RS17080 ^@ http://purl.uniprot.org/uniprot/A4XDT9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS07860 ^@ http://purl.uniprot.org/uniprot/Q2G814 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00790 ^@ http://purl.uniprot.org/uniprot/Q2GC14 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08300 ^@ http://purl.uniprot.org/uniprot/Q2G7S8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/279238:SARO_RS15955 ^@ http://purl.uniprot.org/uniprot/Q2G3J7 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/279238:SARO_RS07170 ^@ http://purl.uniprot.org/uniprot/Q2G8E9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/279238:SARO_RS17285 ^@ http://purl.uniprot.org/uniprot/A4XDX8 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/279238:SARO_RS09670 ^@ http://purl.uniprot.org/uniprot/Q2G704 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS15500 ^@ http://purl.uniprot.org/uniprot/Q2G3T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/279238:SARO_RS05120 ^@ http://purl.uniprot.org/uniprot/Q2G9K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS14490 ^@ http://purl.uniprot.org/uniprot/Q2G4D0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/279238:SARO_RS18425 ^@ http://purl.uniprot.org/uniprot/A4XEK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06010 ^@ http://purl.uniprot.org/uniprot/Q2G925 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/279238:SARO_RS09635 ^@ http://purl.uniprot.org/uniprot/Q2G711 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/279238:SARO_RS07950 ^@ http://purl.uniprot.org/uniprot/Q2G7Z7 ^@ Function|||Similarity ^@ Belongs to the bacterial two-domain DSD family.|||Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways. http://togogenome.org/gene/279238:SARO_RS13440 ^@ http://purl.uniprot.org/uniprot/Q2G4Z0 ^@ Similarity ^@ Belongs to the GSP N family. http://togogenome.org/gene/279238:SARO_RS00580 ^@ http://purl.uniprot.org/uniprot/Q2GC58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/279238:SARO_RS14285 ^@ http://purl.uniprot.org/uniprot/Q2G4H1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS16620 ^@ http://purl.uniprot.org/uniprot/Q2G365 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/279238:SARO_RS11820 ^@ http://purl.uniprot.org/uniprot/Q2G5T7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS04970 ^@ http://purl.uniprot.org/uniprot/Q2G9N3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS12295 ^@ http://purl.uniprot.org/uniprot/Q2G5J4 ^@ Function|||Similarity ^@ Belongs to the SsuD family.|||Part of the alkanesulfonate monooxygenase (sulfo-ASMO) pathway, a D-sulfoquinovose degradation pathway that enables the complete utilization of all carbons within sulfoquinovose (SQ) with concomitant production of inorganic sulfite (Ref.2). Catalyzes the oxidative desulfurization of sulfoquinovose to sulfite and 6-dehydro-D-glucose (Ref.2). http://togogenome.org/gene/279238:SARO_RS07020 ^@ http://purl.uniprot.org/uniprot/Q2G8H9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/279238:SARO_RS02555 ^@ http://purl.uniprot.org/uniprot/Q2GB15 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS00330 ^@ http://purl.uniprot.org/uniprot/Q2GCA8 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/279238:SARO_RS05630 ^@ http://purl.uniprot.org/uniprot/Q2G999 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS17260 ^@ http://purl.uniprot.org/uniprot/A4XDX3 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/279238:SARO_RS07340 ^@ http://purl.uniprot.org/uniprot/Q2G8B7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS12525 ^@ http://purl.uniprot.org/uniprot/Q2G5E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/279238:SARO_RS17185 ^@ http://purl.uniprot.org/uniprot/A4XDW0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09835 ^@ http://purl.uniprot.org/uniprot/Q2G6X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08995 ^@ http://purl.uniprot.org/uniprot/Q2G7D6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS01980 ^@ http://purl.uniprot.org/uniprot/Q2GBC9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/279238:SARO_RS06825 ^@ http://purl.uniprot.org/uniprot/Q2G8L7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/279238:SARO_RS12720 ^@ http://purl.uniprot.org/uniprot/Q2G5B1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/279238:SARO_RS06275 ^@ http://purl.uniprot.org/uniprot/Q2G8X5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/279238:SARO_RS11915 ^@ http://purl.uniprot.org/uniprot/Q2G5R9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/279238:SARO_RS06340 ^@ http://purl.uniprot.org/uniprot/Q2G8W2 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS11465 ^@ http://purl.uniprot.org/uniprot/Q2G609 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/279238:SARO_RS06270 ^@ http://purl.uniprot.org/uniprot/Q2G8X6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/279238:SARO_RS04015 ^@ http://purl.uniprot.org/uniprot/Q2GA74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS14250 ^@ http://purl.uniprot.org/uniprot/Q2G4H8 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/279238:SARO_RS09025 ^@ http://purl.uniprot.org/uniprot/Q2G7D0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/279238:SARO_RS02945 ^@ http://purl.uniprot.org/uniprot/Q2GAT5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS03375 ^@ http://purl.uniprot.org/uniprot/Q2GAK0 ^@ Cofactor ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/279238:SARO_RS12650 ^@ http://purl.uniprot.org/uniprot/Q2G5C5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS05660 ^@ http://purl.uniprot.org/uniprot/Q2G993 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS19375 ^@ http://purl.uniprot.org/uniprot/A4XF49 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS00780 ^@ http://purl.uniprot.org/uniprot/Q2GC16 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/279238:SARO_RS18525 ^@ http://purl.uniprot.org/uniprot/A4XEM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00610 ^@ http://purl.uniprot.org/uniprot/Q2GC51 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/279238:SARO_RS00680 ^@ http://purl.uniprot.org/uniprot/Q2GC37 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/279238:SARO_RS13390 ^@ http://purl.uniprot.org/uniprot/Q2G500 ^@ Similarity ^@ Belongs to the UPF0174 family. http://togogenome.org/gene/279238:SARO_RS13560 ^@ http://purl.uniprot.org/uniprot/Q2G4W6 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS11375 ^@ http://purl.uniprot.org/uniprot/Q2G625 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/279238:SARO_RS05420 ^@ http://purl.uniprot.org/uniprot/Q2G9E2 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/279238:SARO_RS12760 ^@ http://purl.uniprot.org/uniprot/Q2G5A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16690 ^@ http://purl.uniprot.org/uniprot/Q2G351 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/279238:SARO_RS11790 ^@ http://purl.uniprot.org/uniprot/Q2G5U3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS16900 ^@ http://purl.uniprot.org/uniprot/Q2G310 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/279238:SARO_RS15540 ^@ http://purl.uniprot.org/uniprot/Q2G3S8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/279238:SARO_RS09655 ^@ http://purl.uniprot.org/uniprot/Q2G707 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/279238:SARO_RS04750 ^@ http://purl.uniprot.org/uniprot/Q2G9S7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/279238:SARO_RS06515 ^@ http://purl.uniprot.org/uniprot/Q2G8S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/279238:SARO_RS02025 ^@ http://purl.uniprot.org/uniprot/Q2GBC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS12685 ^@ http://purl.uniprot.org/uniprot/Q2G5B8 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/279238:SARO_RS03200 ^@ http://purl.uniprot.org/uniprot/Q2GAN5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/279238:SARO_RS19500 ^@ http://purl.uniprot.org/uniprot/A4XF73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06105 ^@ http://purl.uniprot.org/uniprot/Q2G907 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00360 ^@ http://purl.uniprot.org/uniprot/Q2GCA3 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/279238:SARO_RS17305 ^@ http://purl.uniprot.org/uniprot/A4XDY2 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS06330 ^@ http://purl.uniprot.org/uniprot/Q2G8W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/279238:SARO_RS01645 ^@ http://purl.uniprot.org/uniprot/Q2GBJ7 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/279238:SARO_RS14830 ^@ http://purl.uniprot.org/uniprot/Q2G463 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CopC family.|||Periplasm http://togogenome.org/gene/279238:SARO_RS18700 ^@ http://purl.uniprot.org/uniprot/A4XER4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS10135 ^@ http://purl.uniprot.org/uniprot/Q2G6R9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/279238:SARO_RS11595 ^@ http://purl.uniprot.org/uniprot/Q2G5Y3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS11215 ^@ http://purl.uniprot.org/uniprot/Q2G656 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/279238:SARO_RS06700 ^@ http://purl.uniprot.org/uniprot/Q2G8P0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS02065 ^@ http://purl.uniprot.org/uniprot/Q2GBB2 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/279238:SARO_RS10060 ^@ http://purl.uniprot.org/uniprot/Q2G6T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS12270 ^@ http://purl.uniprot.org/uniprot/Q2G5J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS11365 ^@ http://purl.uniprot.org/uniprot/Q2G627 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/279238:SARO_RS01675 ^@ http://purl.uniprot.org/uniprot/Q2GBJ1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/279238:SARO_RS06235 ^@ http://purl.uniprot.org/uniprot/Q2G8Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS17020 ^@ http://purl.uniprot.org/uniprot/A4XDS8 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS17970 ^@ http://purl.uniprot.org/uniprot/A4XEB8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS02420 ^@ http://purl.uniprot.org/uniprot/Q2GB43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06895 ^@ http://purl.uniprot.org/uniprot/Q2G8K4 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS11880 ^@ http://purl.uniprot.org/uniprot/Q2G5S6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/279238:SARO_RS06250 ^@ http://purl.uniprot.org/uniprot/Q2G8Y0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/279238:SARO_RS05695 ^@ http://purl.uniprot.org/uniprot/Q2G986 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS17105 ^@ http://purl.uniprot.org/uniprot/A4XDU4 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS17965 ^@ http://purl.uniprot.org/uniprot/A4XEB7 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/279238:SARO_RS05080 ^@ http://purl.uniprot.org/uniprot/Q2G9L1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/279238:SARO_RS11405 ^@ http://purl.uniprot.org/uniprot/Q2G619 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS04895 ^@ http://purl.uniprot.org/uniprot/Q2G9P8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/279238:SARO_RS06110 ^@ http://purl.uniprot.org/uniprot/Q2G906 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS05610 ^@ http://purl.uniprot.org/uniprot/Q2G9A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/279238:SARO_RS04575 ^@ http://purl.uniprot.org/uniprot/Q2G9W3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/279238:SARO_RS12550 ^@ http://purl.uniprot.org/uniprot/Q2G5E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/279238:SARO_RS10640 ^@ http://purl.uniprot.org/uniprot/Q2G6G8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/279238:SARO_RS05580 ^@ http://purl.uniprot.org/uniprot/Q2G9A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.|||Cell inner membrane|||Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB). http://togogenome.org/gene/279238:SARO_RS03555 ^@ http://purl.uniprot.org/uniprot/Q2GAG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08810 ^@ http://purl.uniprot.org/uniprot/Q2G7H3 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/279238:SARO_RS00385 ^@ http://purl.uniprot.org/uniprot/Q2GC98 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/279238:SARO_RS04885 ^@ http://purl.uniprot.org/uniprot/Q2G9Q0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS14780 ^@ http://purl.uniprot.org/uniprot/Q2G473 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/279238:SARO_RS12875 ^@ http://purl.uniprot.org/uniprot/Q2G583 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/279238:SARO_RS19170 ^@ http://purl.uniprot.org/uniprot/A4XF07 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS09185 ^@ http://purl.uniprot.org/uniprot/Q2G798 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/279238:SARO_RS07775 ^@ http://purl.uniprot.org/uniprot/Q2G831 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/279238:SARO_RS01380 ^@ http://purl.uniprot.org/uniprot/Q2GBQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS19940 ^@ http://purl.uniprot.org/uniprot/A4XFG1 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS19145 ^@ http://purl.uniprot.org/uniprot/A4XF02 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/279238:SARO_RS08320 ^@ http://purl.uniprot.org/uniprot/Q2G7S4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/279238:SARO_RS05130 ^@ http://purl.uniprot.org/uniprot/Q2G9K0 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/279238:SARO_RS04830 ^@ http://purl.uniprot.org/uniprot/Q2G9R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS17310 ^@ http://purl.uniprot.org/uniprot/A4XDY3 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/279238:SARO_RS06415 ^@ http://purl.uniprot.org/uniprot/Q2G8U6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS19465 ^@ http://purl.uniprot.org/uniprot/A4XF67 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS15935 ^@ http://purl.uniprot.org/uniprot/Q2G3K1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/279238:SARO_RS09015 ^@ http://purl.uniprot.org/uniprot/Q2G7D2 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/279238:SARO_RS11240 ^@ http://purl.uniprot.org/uniprot/Q2G652 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/279238:SARO_RS06100 ^@ http://purl.uniprot.org/uniprot/Q2G908 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS09130 ^@ http://purl.uniprot.org/uniprot/Q2G7A9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS07060 ^@ http://purl.uniprot.org/uniprot/Q2G8H1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/279238:SARO_RS01885 ^@ http://purl.uniprot.org/uniprot/Q2GBE8 ^@ Similarity ^@ Belongs to the SBNO family. http://togogenome.org/gene/279238:SARO_RS05680 ^@ http://purl.uniprot.org/uniprot/Q2G989 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/279238:SARO_RS02795 ^@ http://purl.uniprot.org/uniprot/Q2GAW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08555 ^@ http://purl.uniprot.org/uniprot/Q2G7M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS16145 ^@ http://purl.uniprot.org/uniprot/Q2G3F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/279238:SARO_RS12405 ^@ http://purl.uniprot.org/uniprot/Q2G5H2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS05555 ^@ http://purl.uniprot.org/uniprot/Q2G9B4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS01200 ^@ http://purl.uniprot.org/uniprot/Q2GBT4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/279238:SARO_RS16590 ^@ http://purl.uniprot.org/uniprot/Q2G371 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/279238:SARO_RS05670 ^@ http://purl.uniprot.org/uniprot/Q2G991 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/279238:SARO_RS05915 ^@ http://purl.uniprot.org/uniprot/Q2G942 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS11730 ^@ http://purl.uniprot.org/uniprot/Q2G5V5 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/279238:SARO_RS16760 ^@ http://purl.uniprot.org/uniprot/Q2G338 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS15055 ^@ http://purl.uniprot.org/uniprot/Q2G418 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS17150 ^@ http://purl.uniprot.org/uniprot/A4XDV3 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/279238:SARO_RS04600 ^@ http://purl.uniprot.org/uniprot/Q2G9V7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/279238:SARO_RS16455 ^@ http://purl.uniprot.org/uniprot/Q2G397 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/279238:SARO_RS16830 ^@ http://purl.uniprot.org/uniprot/Q2G324 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/279238:SARO_RS11310 ^@ http://purl.uniprot.org/uniprot/Q2G638 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08250 ^@ http://purl.uniprot.org/uniprot/Q2G7T8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09230 ^@ http://purl.uniprot.org/uniprot/Q2G789 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/279238:SARO_RS01490 ^@ http://purl.uniprot.org/uniprot/Q2GBM8 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/279238:SARO_RS05495 ^@ http://purl.uniprot.org/uniprot/Q2G9C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/279238:SARO_RS18445 ^@ http://purl.uniprot.org/uniprot/A4XEL3 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/279238:SARO_RS14695 ^@ http://purl.uniprot.org/uniprot/Q2G490 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/279238:SARO_RS11760 ^@ http://purl.uniprot.org/uniprot/Q2G5U9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/279238:SARO_RS05990 ^@ http://purl.uniprot.org/uniprot/Q2G929 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/279238:SARO_RS09480 ^@ http://purl.uniprot.org/uniprot/Q2G740 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS00520 ^@ http://purl.uniprot.org/uniprot/Q2GC70 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS19790 ^@ http://purl.uniprot.org/uniprot/A4XFD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06905 ^@ http://purl.uniprot.org/uniprot/Q2G8K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/279238:SARO_RS16680 ^@ http://purl.uniprot.org/uniprot/Q2G353 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/279238:SARO_RS06560 ^@ http://purl.uniprot.org/uniprot/Q2G8R8 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/279238:SARO_RS04530 ^@ http://purl.uniprot.org/uniprot/Q2G9X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF nuclease family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS18750 ^@ http://purl.uniprot.org/uniprot/A4XES4 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/279238:SARO_RS06600 ^@ http://purl.uniprot.org/uniprot/Q2G8R0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/279238:SARO_RS00575 ^@ http://purl.uniprot.org/uniprot/Q2GC59 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS15665 ^@ http://purl.uniprot.org/uniprot/Q2G3Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00775 ^@ http://purl.uniprot.org/uniprot/Q2GC18 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/279238:SARO_RS06680 ^@ http://purl.uniprot.org/uniprot/Q2G8P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/279238:SARO_RS04940 ^@ http://purl.uniprot.org/uniprot/Q2G9N9 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/279238:SARO_RS16200 ^@ http://purl.uniprot.org/uniprot/Q2G3E8 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/279238:SARO_RS02125 ^@ http://purl.uniprot.org/uniprot/Q2GBA0 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/279238:SARO_RS14375 ^@ http://purl.uniprot.org/uniprot/Q2G4F3 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/279238:SARO_RS10810 ^@ http://purl.uniprot.org/uniprot/Q2G6D6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/279238:SARO_RS18745 ^@ http://purl.uniprot.org/uniprot/A4XES3 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/279238:SARO_RS02930 ^@ http://purl.uniprot.org/uniprot/Q2GAT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS05295 ^@ http://purl.uniprot.org/uniprot/Q2G9G7 ^@ Function|||Similarity ^@ A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.|||Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily. http://togogenome.org/gene/279238:SARO_RS01360 ^@ http://purl.uniprot.org/uniprot/Q2GBQ4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/279238:SARO_RS09945 ^@ http://purl.uniprot.org/uniprot/Q2G6V4 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/279238:SARO_RS06290 ^@ http://purl.uniprot.org/uniprot/Q2G8X2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/279238:SARO_RS00930 ^@ http://purl.uniprot.org/uniprot/Q2GBY7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/279238:SARO_RS03740 ^@ http://purl.uniprot.org/uniprot/Q2GAC8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/279238:SARO_RS01550 ^@ http://purl.uniprot.org/uniprot/Q2GBL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS06970 ^@ http://purl.uniprot.org/uniprot/Q2G8I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08720 ^@ http://purl.uniprot.org/uniprot/Q2G7J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/279238:SARO_RS10355 ^@ http://purl.uniprot.org/uniprot/Q2G6M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/279238:SARO_RS03595 ^@ http://purl.uniprot.org/uniprot/Q2GAF7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS08805 ^@ http://purl.uniprot.org/uniprot/Q2G7H4 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/279238:SARO_RS00795 ^@ http://purl.uniprot.org/uniprot/Q2GC13 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS09060 ^@ http://purl.uniprot.org/uniprot/Q2G7C3 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/279238:SARO_RS14635 ^@ http://purl.uniprot.org/uniprot/Q2G4A1 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/279238:SARO_RS07095 ^@ http://purl.uniprot.org/uniprot/Q2G8G4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/279238:SARO_RS17300 ^@ http://purl.uniprot.org/uniprot/A4XDY1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS14210 ^@ http://purl.uniprot.org/uniprot/Q2G4I6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01065 ^@ http://purl.uniprot.org/uniprot/Q2GBW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/279238:SARO_RS18390 ^@ http://purl.uniprot.org/uniprot/A4XEK2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/279238:SARO_RS09100 ^@ http://purl.uniprot.org/uniprot/Q2G7B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0314 family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS16100 ^@ http://purl.uniprot.org/uniprot/Q2G3G8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/279238:SARO_RS12075 ^@ http://purl.uniprot.org/uniprot/Q2G5N7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/279238:SARO_RS19305 ^@ http://purl.uniprot.org/uniprot/A4XF35 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/279238:SARO_RS07040 ^@ http://purl.uniprot.org/uniprot/Q2G8H5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/279238:SARO_RS11110 ^@ http://purl.uniprot.org/uniprot/Q2G677 ^@ Similarity ^@ Belongs to the SBNO family. http://togogenome.org/gene/279238:SARO_RS01530 ^@ http://purl.uniprot.org/uniprot/Q2GBM0 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/279238:SARO_RS10770 ^@ http://purl.uniprot.org/uniprot/Q2G6E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CopC family.|||Periplasm http://togogenome.org/gene/279238:SARO_RS01705 ^@ http://purl.uniprot.org/uniprot/Q2GBI5 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/279238:SARO_RS02825 ^@ http://purl.uniprot.org/uniprot/Q2GAW0 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/279238:SARO_RS11320 ^@ http://purl.uniprot.org/uniprot/Q2G636 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/279238:SARO_RS16670 ^@ http://purl.uniprot.org/uniprot/Q2G355 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/279238:SARO_RS10460 ^@ http://purl.uniprot.org/uniprot/Q2G6K5 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/279238:SARO_RS17330 ^@ http://purl.uniprot.org/uniprot/A4XDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS10420 ^@ http://purl.uniprot.org/uniprot/Q2G6L2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/279238:SARO_RS07050 ^@ http://purl.uniprot.org/uniprot/Q2G8H3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/279238:SARO_RS10545 ^@ http://purl.uniprot.org/uniprot/Q2G6I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS15990 ^@ http://purl.uniprot.org/uniprot/Q2G3J0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00705 ^@ http://purl.uniprot.org/uniprot/Q2GC32 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/279238:SARO_RS20000 ^@ http://purl.uniprot.org/uniprot/A4XFH3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS03380 ^@ http://purl.uniprot.org/uniprot/Q2GAJ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/279238:SARO_RS19270 ^@ http://purl.uniprot.org/uniprot/A4XF27 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS11710 ^@ http://purl.uniprot.org/uniprot/Q2G5V9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/279238:SARO_RS15800 ^@ http://purl.uniprot.org/uniprot/Q2G3M7 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS02675 ^@ http://purl.uniprot.org/uniprot/Q2GAY9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS05135 ^@ http://purl.uniprot.org/uniprot/Q2G9J9 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/279238:SARO_RS11350 ^@ http://purl.uniprot.org/uniprot/Q2G630 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/279238:SARO_RS01475 ^@ http://purl.uniprot.org/uniprot/Q2GBN1 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/279238:SARO_RS16320 ^@ http://purl.uniprot.org/uniprot/Q2G3C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS04975 ^@ http://purl.uniprot.org/uniprot/Q2G9N2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS15375 ^@ http://purl.uniprot.org/uniprot/Q2G3V9 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/279238:SARO_RS13250 ^@ http://purl.uniprot.org/uniprot/Q2G510 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16610 ^@ http://purl.uniprot.org/uniprot/Q2G367 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/279238:SARO_RS04305 ^@ http://purl.uniprot.org/uniprot/Q2GA18 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS14220 ^@ http://purl.uniprot.org/uniprot/Q2G4I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS09090 ^@ http://purl.uniprot.org/uniprot/Q2G7B7 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS04630 ^@ http://purl.uniprot.org/uniprot/Q2G9V1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaE family.|||Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/279238:SARO_RS03970 ^@ http://purl.uniprot.org/uniprot/Q2GA83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06855 ^@ http://purl.uniprot.org/uniprot/Q2G8L2 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/279238:SARO_RS16520 ^@ http://purl.uniprot.org/uniprot/Q2G383 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS13500 ^@ http://purl.uniprot.org/uniprot/Q2G4X8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS05625 ^@ http://purl.uniprot.org/uniprot/Q2G9A0 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS09390 ^@ http://purl.uniprot.org/uniprot/Q2G758 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS19705 ^@ http://purl.uniprot.org/uniprot/A4XFB4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS03460 ^@ http://purl.uniprot.org/uniprot/Q2GAI3 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/279238:SARO_RS09005 ^@ http://purl.uniprot.org/uniprot/Q2G7D4 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/279238:SARO_RS12735 ^@ http://purl.uniprot.org/uniprot/Q2G5A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/279238:SARO_RS04915 ^@ http://purl.uniprot.org/uniprot/Q2G9P4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS18130 ^@ http://purl.uniprot.org/uniprot/A4XEF0 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/279238:SARO_RS06495 ^@ http://purl.uniprot.org/uniprot/Q2G8T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS16950 ^@ http://purl.uniprot.org/uniprot/Q2G300 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/279238:SARO_RS04795 ^@ http://purl.uniprot.org/uniprot/Q2G9R8 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/279238:SARO_RS20010 ^@ http://purl.uniprot.org/uniprot/A4XFH5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS05715 ^@ http://purl.uniprot.org/uniprot/Q2G983 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS14505 ^@ http://purl.uniprot.org/uniprot/Q2G4C7 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/279238:SARO_RS04310 ^@ http://purl.uniprot.org/uniprot/Q2GA17 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/279238:SARO_RS14805 ^@ http://purl.uniprot.org/uniprot/Q2G468 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/279238:SARO_RS16130 ^@ http://purl.uniprot.org/uniprot/Q2G3G2 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/279238:SARO_RS20275 ^@ http://purl.uniprot.org/uniprot/Q2G4U9 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/279238:SARO_RS10700 ^@ http://purl.uniprot.org/uniprot/Q2G6F6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/279238:SARO_RS14725 ^@ http://purl.uniprot.org/uniprot/Q2G484 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/279238:SARO_RS07230 ^@ http://purl.uniprot.org/uniprot/Q2G8D7 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/279238:SARO_RS01115 ^@ http://purl.uniprot.org/uniprot/Q2GBV2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS06690 ^@ http://purl.uniprot.org/uniprot/Q2G8P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/279238:SARO_RS14360 ^@ http://purl.uniprot.org/uniprot/Q2G4F6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/279238:SARO_RS01870 ^@ http://purl.uniprot.org/uniprot/Q2GBF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06695 ^@ http://purl.uniprot.org/uniprot/Q2G8P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS03995 ^@ http://purl.uniprot.org/uniprot/Q2GA78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS07155 ^@ http://purl.uniprot.org/uniprot/Q2G8F2 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/279238:SARO_RS12390 ^@ http://purl.uniprot.org/uniprot/Q2G5H5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS09820 ^@ http://purl.uniprot.org/uniprot/Q2G6X6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/279238:SARO_RS16510 ^@ http://purl.uniprot.org/uniprot/Q2G385 ^@ Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.|||Sulfate-activating enzymes, NodP and NodQ, may be physically associated.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/279238:SARO_RS05895 ^@ http://purl.uniprot.org/uniprot/Q2G946 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/279238:SARO_RS16155 ^@ http://purl.uniprot.org/uniprot/Q2G3F7 ^@ Similarity ^@ Belongs to the UPF0311 family. http://togogenome.org/gene/279238:SARO_RS16740 ^@ http://purl.uniprot.org/uniprot/Q2G341 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS07715 ^@ http://purl.uniprot.org/uniprot/Q2G842 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS07695 ^@ http://purl.uniprot.org/uniprot/Q2G847 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS00300 ^@ http://purl.uniprot.org/uniprot/Q2GCB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS17820 ^@ http://purl.uniprot.org/uniprot/A4XE88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/279238:SARO_RS05190 ^@ http://purl.uniprot.org/uniprot/Q2G9I7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/279238:SARO_RS14365 ^@ http://purl.uniprot.org/uniprot/Q2G4F5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/279238:SARO_RS16240 ^@ http://purl.uniprot.org/uniprot/Q2G3D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/279238:SARO_RS10005 ^@ http://purl.uniprot.org/uniprot/Q2G6U3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||May bind 1 zinc ion per subunit.|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/279238:SARO_RS08940 ^@ http://purl.uniprot.org/uniprot/Q2G7E7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS06875 ^@ http://purl.uniprot.org/uniprot/Q2G8K8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/279238:SARO_RS18915 ^@ http://purl.uniprot.org/uniprot/A4XEV7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS05385 ^@ http://purl.uniprot.org/uniprot/Q2G9E9 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/279238:SARO_RS05805 ^@ http://purl.uniprot.org/uniprot/Q2G964 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/279238:SARO_RS11330 ^@ http://purl.uniprot.org/uniprot/Q2G634 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/279238:SARO_RS04045 ^@ http://purl.uniprot.org/uniprot/Q2GA68 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/279238:SARO_RS13545 ^@ http://purl.uniprot.org/uniprot/Q2G4W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/279238:SARO_RS08305 ^@ http://purl.uniprot.org/uniprot/Q2G7S7 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/279238:SARO_RS06500 ^@ http://purl.uniprot.org/uniprot/Q2G8T0 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/279238:SARO_RS02600 ^@ http://purl.uniprot.org/uniprot/Q2GB06 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/279238:SARO_RS07855 ^@ http://purl.uniprot.org/uniprot/Q2G815 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS08460 ^@ http://purl.uniprot.org/uniprot/Q2G7P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aromatic amine dehydrogenase light chain family.|||Heterotetramer of two light and two heavy chains.|||Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.|||Periplasm http://togogenome.org/gene/279238:SARO_RS05265 ^@ http://purl.uniprot.org/uniprot/Q2G9H3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/279238:SARO_RS14845 ^@ http://purl.uniprot.org/uniprot/Q2G460 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/279238:SARO_RS11270 ^@ http://purl.uniprot.org/uniprot/Q2G646 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS02920 ^@ http://purl.uniprot.org/uniprot/Q2GAU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/279238:SARO_RS13105 ^@ http://purl.uniprot.org/uniprot/Q2G538 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS14760 ^@ http://purl.uniprot.org/uniprot/Q2G477 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/279238:SARO_RS13450 ^@ http://purl.uniprot.org/uniprot/Q2G4Y8 ^@ Similarity ^@ Belongs to the GSP L family. http://togogenome.org/gene/279238:SARO_RS11120 ^@ http://purl.uniprot.org/uniprot/Q2G675 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/279238:SARO_RS19055 ^@ http://purl.uniprot.org/uniprot/A4XEY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS07545 ^@ http://purl.uniprot.org/uniprot/Q2G877 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/279238:SARO_RS08215 ^@ http://purl.uniprot.org/uniprot/Q2G7U5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/279238:SARO_RS10270 ^@ http://purl.uniprot.org/uniprot/Q2G6P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS16975 ^@ http://purl.uniprot.org/uniprot/A4XDR9 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS20015 ^@ http://purl.uniprot.org/uniprot/A4XFH6 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. http://togogenome.org/gene/279238:SARO_RS01295 ^@ http://purl.uniprot.org/uniprot/Q2GBR6 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. http://togogenome.org/gene/279238:SARO_RS00495 ^@ http://purl.uniprot.org/uniprot/Q2GC75 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/279238:SARO_RS01085 ^@ http://purl.uniprot.org/uniprot/Q2GBV8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/279238:SARO_RS11335 ^@ http://purl.uniprot.org/uniprot/Q2G633 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/279238:SARO_RS06295 ^@ http://purl.uniprot.org/uniprot/Q2G8X1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS07970 ^@ http://purl.uniprot.org/uniprot/Q2G7Z3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS00295 ^@ http://purl.uniprot.org/uniprot/Q2GCB5 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/279238:SARO_RS13600 ^@ http://purl.uniprot.org/uniprot/Q2G4V8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/279238:SARO_RS12510 ^@ http://purl.uniprot.org/uniprot/Q2G5F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00460 ^@ http://purl.uniprot.org/uniprot/Q2GC82 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/279238:SARO_RS12730 ^@ http://purl.uniprot.org/uniprot/Q2G5A9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/279238:SARO_RS15440 ^@ http://purl.uniprot.org/uniprot/Q2G3U5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/279238:SARO_RS05880 ^@ http://purl.uniprot.org/uniprot/Q2G949 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/279238:SARO_RS05875 ^@ http://purl.uniprot.org/uniprot/Q2G950 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/279238:SARO_RS06805 ^@ http://purl.uniprot.org/uniprot/Q2G8M1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/279238:SARO_RS14800 ^@ http://purl.uniprot.org/uniprot/Q2G469 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/279238:SARO_RS08715 ^@ http://purl.uniprot.org/uniprot/Q2G7J2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS03370 ^@ http://purl.uniprot.org/uniprot/Q2GAK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS08730 ^@ http://purl.uniprot.org/uniprot/Q2G7I9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/279238:SARO_RS18795 ^@ http://purl.uniprot.org/uniprot/A4XET3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06610 ^@ http://purl.uniprot.org/uniprot/Q2G8Q8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/279238:SARO_RS08740 ^@ http://purl.uniprot.org/uniprot/Q2G7I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS02565 ^@ http://purl.uniprot.org/uniprot/Q2GB13 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01415 ^@ http://purl.uniprot.org/uniprot/Q2GBP3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00215 ^@ http://purl.uniprot.org/uniprot/Q2G2Z1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS00200 ^@ http://purl.uniprot.org/uniprot/Q2G2Z5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/279238:SARO_RS13360 ^@ http://purl.uniprot.org/uniprot/Q2G506 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.|||Cell inner membrane|||Homodimer.|||Mediates the ATP-dependent export of glutathione-conjugated substrates, such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions, such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons, such as dinitrobenzene. http://togogenome.org/gene/279238:SARO_RS12885 ^@ http://purl.uniprot.org/uniprot/Q2G581 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/279238:SARO_RS03795 ^@ http://purl.uniprot.org/uniprot/Q2GAB7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS16095 ^@ http://purl.uniprot.org/uniprot/Q2G3G9 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/279238:SARO_RS05425 ^@ http://purl.uniprot.org/uniprot/Q2G9E1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/279238:SARO_RS02820 ^@ http://purl.uniprot.org/uniprot/Q2GAW1 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/279238:SARO_RS10200 ^@ http://purl.uniprot.org/uniprot/Q2G6Q6 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/279238:SARO_RS05645 ^@ http://purl.uniprot.org/uniprot/Q2G996 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS04945 ^@ http://purl.uniprot.org/uniprot/Q2G9N8 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/279238:SARO_RS15930 ^@ http://purl.uniprot.org/uniprot/Q2G3K2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS04620 ^@ http://purl.uniprot.org/uniprot/Q2G9V3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/279238:SARO_RS00735 ^@ http://purl.uniprot.org/uniprot/Q2GC26 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS19810 ^@ http://purl.uniprot.org/uniprot/A4XFD5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/279238:SARO_RS07055 ^@ http://purl.uniprot.org/uniprot/Q2G8H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/279238:SARO_RS09385 ^@ http://purl.uniprot.org/uniprot/Q2G759 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS12200 ^@ http://purl.uniprot.org/uniprot/Q2G5L3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/279238:SARO_RS16905 ^@ http://purl.uniprot.org/uniprot/Q2G309 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/279238:SARO_RS08445 ^@ http://purl.uniprot.org/uniprot/Q2G7P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic amine dehydrogenase heavy chain family.|||Periplasm http://togogenome.org/gene/279238:SARO_RS08825 ^@ http://purl.uniprot.org/uniprot/Q2G7H0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/279238:SARO_RS08595 ^@ http://purl.uniprot.org/uniprot/Q2G7L6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/279238:SARO_RS01465 ^@ http://purl.uniprot.org/uniprot/Q2GBN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/279238:SARO_RS04675 ^@ http://purl.uniprot.org/uniprot/Q2G9U2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/279238:SARO_RS00020 ^@ http://purl.uniprot.org/uniprot/Q2GCF7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/279238:SARO_RS04905 ^@ http://purl.uniprot.org/uniprot/Q2G9P6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS02180 ^@ http://purl.uniprot.org/uniprot/Q2GB90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/279238:SARO_RS14325 ^@ http://purl.uniprot.org/uniprot/Q2G4G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/279238:SARO_RS11015 ^@ http://purl.uniprot.org/uniprot/Q2G694 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS14190 ^@ http://purl.uniprot.org/uniprot/Q2G4J0 ^@ Function ^@ Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/279238:SARO_RS12025 ^@ http://purl.uniprot.org/uniprot/Q2G5P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/279238:SARO_RS14810 ^@ http://purl.uniprot.org/uniprot/Q2G467 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/279238:SARO_RS12465 ^@ http://purl.uniprot.org/uniprot/Q2G5G0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS17045 ^@ http://purl.uniprot.org/uniprot/A4XDT2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS16720 ^@ http://purl.uniprot.org/uniprot/Q2G345 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/279238:SARO_RS14380 ^@ http://purl.uniprot.org/uniprot/Q2G4F2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/279238:SARO_RS04495 ^@ http://purl.uniprot.org/uniprot/Q2G9X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS02415 ^@ http://purl.uniprot.org/uniprot/Q2GB44 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/279238:SARO_RS12205 ^@ http://purl.uniprot.org/uniprot/Q2G5L2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/279238:SARO_RS01950 ^@ http://purl.uniprot.org/uniprot/Q2GBD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16175 ^@ http://purl.uniprot.org/uniprot/Q2G3F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16065 ^@ http://purl.uniprot.org/uniprot/Q2G3H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS07525 ^@ http://purl.uniprot.org/uniprot/Q2G881 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS06685 ^@ http://purl.uniprot.org/uniprot/Q2G8P3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS18645 ^@ http://purl.uniprot.org/uniprot/A4XEQ3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS12430 ^@ http://purl.uniprot.org/uniprot/Q2G5G7 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/279238:SARO_RS14680 ^@ http://purl.uniprot.org/uniprot/Q2G492 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/279238:SARO_RS12750 ^@ http://purl.uniprot.org/uniprot/Q2G5A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16840 ^@ http://purl.uniprot.org/uniprot/Q2G322 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/279238:SARO_RS19590 ^@ http://purl.uniprot.org/uniprot/A4XF91 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS14410 ^@ http://purl.uniprot.org/uniprot/Q2G4E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/279238:SARO_RS01060 ^@ http://purl.uniprot.org/uniprot/Q2GBW3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/279238:SARO_RS10485 ^@ http://purl.uniprot.org/uniprot/Q2G6K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09600 ^@ http://purl.uniprot.org/uniprot/Q2G718 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS09170 ^@ http://purl.uniprot.org/uniprot/Q2G7A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/279238:SARO_RS11545 ^@ http://purl.uniprot.org/uniprot/Q2G5Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/279238:SARO_RS05720 ^@ http://purl.uniprot.org/uniprot/Q2G982 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS12400 ^@ http://purl.uniprot.org/uniprot/Q2G5H3 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/279238:SARO_RS08970 ^@ http://purl.uniprot.org/uniprot/Q2G7E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS04490 ^@ http://purl.uniprot.org/uniprot/Q2G9Y0 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/279238:SARO_RS04085 ^@ http://purl.uniprot.org/uniprot/Q2GA60 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/279238:SARO_RS01230 ^@ http://purl.uniprot.org/uniprot/Q2GBS9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/279238:SARO_RS19975 ^@ http://purl.uniprot.org/uniprot/A4XFG8 ^@ Function ^@ May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit. http://togogenome.org/gene/279238:SARO_RS20145 ^@ http://purl.uniprot.org/uniprot/Q2G9S6 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/279238:SARO_RS11620 ^@ http://purl.uniprot.org/uniprot/Q2G5X8 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06505 ^@ http://purl.uniprot.org/uniprot/Q2G8S9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS15810 ^@ http://purl.uniprot.org/uniprot/Q2G3M5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/279238:SARO_RS11070 ^@ http://purl.uniprot.org/uniprot/Q2G684 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/279238:SARO_RS05335 ^@ http://purl.uniprot.org/uniprot/Q2G9F9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS02665 ^@ http://purl.uniprot.org/uniprot/Q2GAZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06915 ^@ http://purl.uniprot.org/uniprot/Q2G8K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/279238:SARO_RS19930 ^@ http://purl.uniprot.org/uniprot/A4XFF9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS04740 ^@ http://purl.uniprot.org/uniprot/Q2G9S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.|||Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).|||Homodimer or monomer when oxidized or reduced, respectively.|||chloroplast http://togogenome.org/gene/279238:SARO_RS04055 ^@ http://purl.uniprot.org/uniprot/Q2GA65 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/279238:SARO_RS15720 ^@ http://purl.uniprot.org/uniprot/Q2G3P3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/279238:SARO_RS05835 ^@ http://purl.uniprot.org/uniprot/Q2G958 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/279238:SARO_RS06320 ^@ http://purl.uniprot.org/uniprot/Q2G8W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/279238:SARO_RS17100 ^@ http://purl.uniprot.org/uniprot/A4XDU3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/279238:SARO_RS07390 ^@ http://purl.uniprot.org/uniprot/Q2G8A7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/279238:SARO_RS01595 ^@ http://purl.uniprot.org/uniprot/Q2GBK7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/279238:SARO_RS00370 ^@ http://purl.uniprot.org/uniprot/Q2GCA1 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/279238:SARO_RS10665 ^@ http://purl.uniprot.org/uniprot/Q2G6G3 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/279238:SARO_RS13160 ^@ http://purl.uniprot.org/uniprot/Q2G527 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS17420 ^@ http://purl.uniprot.org/uniprot/A4XE07 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/279238:SARO_RS10430 ^@ http://purl.uniprot.org/uniprot/Q2G6L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/279238:SARO_RS03600 ^@ http://purl.uniprot.org/uniprot/Q2GAF6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/279238:SARO_RS02695 ^@ http://purl.uniprot.org/uniprot/Q2GAY5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS14895 ^@ http://purl.uniprot.org/uniprot/Q2G450 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS02705 ^@ http://purl.uniprot.org/uniprot/Q2GAY3 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS13055 ^@ http://purl.uniprot.org/uniprot/Q2G547 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rickettsiale 17 kDa surface antigen family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS19495 ^@ http://purl.uniprot.org/uniprot/A4XF72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS05465 ^@ http://purl.uniprot.org/uniprot/Q2G9D3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/279238:SARO_RS05435 ^@ http://purl.uniprot.org/uniprot/Q2G9D9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS13530 ^@ http://purl.uniprot.org/uniprot/Q2G4X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS08005 ^@ http://purl.uniprot.org/uniprot/Q2G7Y6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08785 ^@ http://purl.uniprot.org/uniprot/Q2G7H8 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/279238:SARO_RS05775 ^@ http://purl.uniprot.org/uniprot/Q2G970 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS12425 ^@ http://purl.uniprot.org/uniprot/Q2G5G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS02095 ^@ http://purl.uniprot.org/uniprot/Q2GBA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS00785 ^@ http://purl.uniprot.org/uniprot/Q2GC15 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS16945 ^@ http://purl.uniprot.org/uniprot/Q2G301 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS09235 ^@ http://purl.uniprot.org/uniprot/Q2G788 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/279238:SARO_RS07185 ^@ http://purl.uniprot.org/uniprot/Q2G8E6 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/279238:SARO_RS00965 ^@ http://purl.uniprot.org/uniprot/Q2GBY1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/279238:SARO_RS00995 ^@ http://purl.uniprot.org/uniprot/Q2GBX5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/279238:SARO_RS03960 ^@ http://purl.uniprot.org/uniprot/Q2GA85 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS17010 ^@ http://purl.uniprot.org/uniprot/A4XDS6 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS00530 ^@ http://purl.uniprot.org/uniprot/Q2GC68 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/279238:SARO_RS12645 ^@ http://purl.uniprot.org/uniprot/Q2G5C6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS16755 ^@ http://purl.uniprot.org/uniprot/Q2G339 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/279238:SARO_RS00145 ^@ http://purl.uniprot.org/uniprot/Q2GCD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/279238:SARO_RS16985 ^@ http://purl.uniprot.org/uniprot/A4XDS1 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/279238:SARO_RS10470 ^@ http://purl.uniprot.org/uniprot/Q2G6K3 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/279238:SARO_RS02970 ^@ http://purl.uniprot.org/uniprot/Q2GAT0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/279238:SARO_RS02890 ^@ http://purl.uniprot.org/uniprot/Q2GAU7 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/279238:SARO_RS19730 ^@ http://purl.uniprot.org/uniprot/A4XFB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS16735 ^@ http://purl.uniprot.org/uniprot/Q2G342 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/279238:SARO_RS05525 ^@ http://purl.uniprot.org/uniprot/Q2G9C0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/279238:SARO_RS05885 ^@ http://purl.uniprot.org/uniprot/Q2G948 ^@ Function|||Subunit ^@ E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/279238:SARO_RS00720 ^@ http://purl.uniprot.org/uniprot/Q2GC29 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/279238:SARO_RS00060 ^@ http://purl.uniprot.org/uniprot/Q2GCE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/279238:SARO_RS14335 ^@ http://purl.uniprot.org/uniprot/Q2G4G1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/279238:SARO_RS11535 ^@ http://purl.uniprot.org/uniprot/Q2G5Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS08115 ^@ http://purl.uniprot.org/uniprot/Q2G7W4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/279238:SARO_RS10720 ^@ http://purl.uniprot.org/uniprot/Q2G6F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/279238:SARO_RS17090 ^@ http://purl.uniprot.org/uniprot/A4XDU1 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/279238:SARO_RS07165 ^@ http://purl.uniprot.org/uniprot/Q2G8F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/279238:SARO_RS04580 ^@ http://purl.uniprot.org/uniprot/Q2G9W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/279238:SARO_RS09435 ^@ http://purl.uniprot.org/uniprot/Q2G749 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/279238:SARO_RS08735 ^@ http://purl.uniprot.org/uniprot/Q2G7I8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/279238:SARO_RS00675 ^@ http://purl.uniprot.org/uniprot/Q2GC38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/279238:SARO_RS01660 ^@ http://purl.uniprot.org/uniprot/Q2GBJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/279238:SARO_RS01955 ^@ http://purl.uniprot.org/uniprot/Q2GBD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS01445 ^@ http://purl.uniprot.org/uniprot/Q2GBN7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/279238:SARO_RS14660 ^@ http://purl.uniprot.org/uniprot/Q2G496 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/279238:SARO_RS04990 ^@ http://purl.uniprot.org/uniprot/Q2G9M9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS12300 ^@ http://purl.uniprot.org/uniprot/Q2G5J3 ^@ Function|||Similarity ^@ Belongs to the aldo/keto reductase family.|||Part of the alkanesulfonate monooxygenase (sulfo-ASMO) pathway, a D-sulfoquinovose degradation pathway that enables the complete utilization of all carbons within sulfoquinovose (SQ) with concomitant production of inorganic sulfite (Ref.2). Catalyzes the NADP-dependent reduction of 6-dehydro-D-glucose to D-glucose (Ref.2). Can also catalyze the reversible reaction, the formation of 6-dehydro-D-glucose from D-glucose in the presence of NADP(+) (Ref.2). http://togogenome.org/gene/279238:SARO_RS04720 ^@ http://purl.uniprot.org/uniprot/Q2G9T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18905 ^@ http://purl.uniprot.org/uniprot/A4XEV5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS19970 ^@ http://purl.uniprot.org/uniprot/A4XFG7 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/279238:SARO_RS04670 ^@ http://purl.uniprot.org/uniprot/Q2G9U3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS05235 ^@ http://purl.uniprot.org/uniprot/Q2G9H8 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06095 ^@ http://purl.uniprot.org/uniprot/Q2G909 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/279238:SARO_RS02290 ^@ http://purl.uniprot.org/uniprot/Q2G3H0 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/279238:SARO_RS15920 ^@ http://purl.uniprot.org/uniprot/Q2G3K4 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS13190 ^@ http://purl.uniprot.org/uniprot/Q2G521 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS11585 ^@ http://purl.uniprot.org/uniprot/Q2G5Y5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS13520 ^@ http://purl.uniprot.org/uniprot/Q2G4X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16730 ^@ http://purl.uniprot.org/uniprot/Q2G343 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS17620 ^@ http://purl.uniprot.org/uniprot/A4XE48 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/279238:SARO_RS05500 ^@ http://purl.uniprot.org/uniprot/Q2G9C6 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/279238:SARO_RS19530 ^@ http://purl.uniprot.org/uniprot/A4XF79 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS07960 ^@ http://purl.uniprot.org/uniprot/Q2G7Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS16650 ^@ http://purl.uniprot.org/uniprot/Q2G359 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/279238:SARO_RS09955 ^@ http://purl.uniprot.org/uniprot/Q2G6V2 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/279238:SARO_RS10380 ^@ http://purl.uniprot.org/uniprot/Q2G6M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/279238:SARO_RS03410 ^@ http://purl.uniprot.org/uniprot/Q2GAJ3 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/279238:SARO_RS16540 ^@ http://purl.uniprot.org/uniprot/Q2G379 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/279238:SARO_RS05035 ^@ http://purl.uniprot.org/uniprot/Q2G9M0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/279238:SARO_RS18785 ^@ http://purl.uniprot.org/uniprot/A4XET1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/279238:SARO_RS05740 ^@ http://purl.uniprot.org/uniprot/Q2G978 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06355 ^@ http://purl.uniprot.org/uniprot/Q2G8V9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS19655 ^@ http://purl.uniprot.org/uniprot/A4XFA4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS18160 ^@ http://purl.uniprot.org/uniprot/A4XEF6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS17065 ^@ http://purl.uniprot.org/uniprot/A4XDT6 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/279238:SARO_RS18695 ^@ http://purl.uniprot.org/uniprot/A4XER3 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/279238:SARO_RS12480 ^@ http://purl.uniprot.org/uniprot/Q2G5F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06885 ^@ http://purl.uniprot.org/uniprot/Q2G8K6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS10145 ^@ http://purl.uniprot.org/uniprot/Q2G6R7 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS17910 ^@ http://purl.uniprot.org/uniprot/A4XEA6 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/279238:SARO_RS10375 ^@ http://purl.uniprot.org/uniprot/Q2G6M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/279238:SARO_RS06140 ^@ http://purl.uniprot.org/uniprot/Q2G900 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/279238:SARO_RS00055 ^@ http://purl.uniprot.org/uniprot/Q2GCF0 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/279238:SARO_RS09250 ^@ http://purl.uniprot.org/uniprot/Q2G785 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/279238:SARO_RS03935 ^@ http://purl.uniprot.org/uniprot/Q2GA89 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/279238:SARO_RS02285 ^@ http://purl.uniprot.org/uniprot/Q2G3G9 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/279238:SARO_RS03965 ^@ http://purl.uniprot.org/uniprot/Q2GA84 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS14150 ^@ http://purl.uniprot.org/uniprot/Q2G4J8 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/279238:SARO_RS19625 ^@ http://purl.uniprot.org/uniprot/A4XF98 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/279238:SARO_RS11560 ^@ http://purl.uniprot.org/uniprot/Q2G5Z0 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/279238:SARO_RS06350 ^@ http://purl.uniprot.org/uniprot/Q2G8W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/279238:SARO_RS00625 ^@ http://purl.uniprot.org/uniprot/Q2GC48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/279238:SARO_RS01095 ^@ http://purl.uniprot.org/uniprot/Q2GBV6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00250 ^@ http://purl.uniprot.org/uniprot/Q2GCC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS11255 ^@ http://purl.uniprot.org/uniprot/Q2G649 ^@ Similarity ^@ Belongs to the UPF0311 family. http://togogenome.org/gene/279238:SARO_RS14880 ^@ http://purl.uniprot.org/uniprot/Q2G453 ^@ Function|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. http://togogenome.org/gene/279238:SARO_RS02085 ^@ http://purl.uniprot.org/uniprot/Q2GBA8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/279238:SARO_RS02585 ^@ http://purl.uniprot.org/uniprot/Q2GB09 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/279238:SARO_RS09500 ^@ http://purl.uniprot.org/uniprot/Q2G736 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/279238:SARO_RS06090 ^@ http://purl.uniprot.org/uniprot/Q2G910 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/279238:SARO_RS10570 ^@ http://purl.uniprot.org/uniprot/Q2G6I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS08265 ^@ http://purl.uniprot.org/uniprot/Q2G7T5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS10130 ^@ http://purl.uniprot.org/uniprot/Q2G6S0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/279238:SARO_RS06260 ^@ http://purl.uniprot.org/uniprot/Q2G8X8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/279238:SARO_RS19225 ^@ http://purl.uniprot.org/uniprot/A4XF18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS01005 ^@ http://purl.uniprot.org/uniprot/Q2GBX3 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/279238:SARO_RS04250 ^@ http://purl.uniprot.org/uniprot/Q2GA28 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/279238:SARO_RS15400 ^@ http://purl.uniprot.org/uniprot/Q2G3V4 ^@ Caution|||Similarity ^@ Belongs to the peptidase S8 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS02860 ^@ http://purl.uniprot.org/uniprot/Q2GAV3 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/279238:SARO_RS02115 ^@ http://purl.uniprot.org/uniprot/Q2GBA2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/279238:SARO_RS08690 ^@ http://purl.uniprot.org/uniprot/Q2G7J7 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/279238:SARO_RS00660 ^@ http://purl.uniprot.org/uniprot/Q2GC41 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/279238:SARO_RS18080 ^@ http://purl.uniprot.org/uniprot/A4XEE0 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/279238:SARO_RS09195 ^@ http://purl.uniprot.org/uniprot/Q2G796 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/279238:SARO_RS00115 ^@ http://purl.uniprot.org/uniprot/Q2GCD8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/279238:SARO_RS07090 ^@ http://purl.uniprot.org/uniprot/Q2G8G5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/279238:SARO_RS11540 ^@ http://purl.uniprot.org/uniprot/Q2G5Z4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/279238:SARO_RS19130 ^@ http://purl.uniprot.org/uniprot/A4XEZ9 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS06005 ^@ http://purl.uniprot.org/uniprot/Q2G926 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS15450 ^@ http://purl.uniprot.org/uniprot/Q2G3U3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/279238:SARO_RS16305 ^@ http://purl.uniprot.org/uniprot/Q2G3C6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS02615 ^@ http://purl.uniprot.org/uniprot/Q2GB03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS12980 ^@ http://purl.uniprot.org/uniprot/Q2G562 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CcoP / FixP family.|||Binds 2 heme C groups per subunit.|||C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.|||Cell inner membrane|||Component of the cbb3-type cytochrome c oxidase.|||Membrane http://togogenome.org/gene/279238:SARO_RS08755 ^@ http://purl.uniprot.org/uniprot/Q2G7I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS14530 ^@ http://purl.uniprot.org/uniprot/Q2G4C2 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/279238:SARO_RS06960 ^@ http://purl.uniprot.org/uniprot/Q2G8J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/279238:SARO_RS03440 ^@ http://purl.uniprot.org/uniprot/Q2GAI7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/279238:SARO_RS02230 ^@ http://purl.uniprot.org/uniprot/Q2GB80 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS06305 ^@ http://purl.uniprot.org/uniprot/Q2G8W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS18970 ^@ http://purl.uniprot.org/uniprot/A4XEW8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS05560 ^@ http://purl.uniprot.org/uniprot/Q2G9B3 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/279238:SARO_RS13000 ^@ http://purl.uniprot.org/uniprot/Q2G558 ^@ Similarity ^@ Belongs to the OmpW/AlkL family. http://togogenome.org/gene/279238:SARO_RS05175 ^@ http://purl.uniprot.org/uniprot/Q2G9J0 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/279238:SARO_RS10585 ^@ http://purl.uniprot.org/uniprot/Q2G6H9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS02710 ^@ http://purl.uniprot.org/uniprot/Q2GAY2 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/279238:SARO_RS03780 ^@ http://purl.uniprot.org/uniprot/Q2GAC0 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/279238:SARO_RS07315 ^@ http://purl.uniprot.org/uniprot/Q2G8C2 ^@ Similarity ^@ Belongs to the IS21/IS1162 putative ATP-binding protein family. http://togogenome.org/gene/279238:SARO_RS05210 ^@ http://purl.uniprot.org/uniprot/Q2G9I3 ^@ Function|||Subunit ^@ E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/279238:SARO_RS08700 ^@ http://purl.uniprot.org/uniprot/Q2G7J5 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/279238:SARO_RS14060 ^@ http://purl.uniprot.org/uniprot/Q2G4L6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS07575 ^@ http://purl.uniprot.org/uniprot/Q2G870 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell inner membrane|||Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. http://togogenome.org/gene/279238:SARO_RS06335 ^@ http://purl.uniprot.org/uniprot/Q2G8W3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/279238:SARO_RS15525 ^@ http://purl.uniprot.org/uniprot/Q2G3S9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/279238:SARO_RS05545 ^@ http://purl.uniprot.org/uniprot/Q2G9B6 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/279238:SARO_RS04825 ^@ http://purl.uniprot.org/uniprot/Q2G9R2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/279238:SARO_RS01560 ^@ http://purl.uniprot.org/uniprot/Q2GBL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS11610 ^@ http://purl.uniprot.org/uniprot/Q2G5Y0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/279238:SARO_RS04125 ^@ http://purl.uniprot.org/uniprot/Q2GA52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/279238:SARO_RS16060 ^@ http://purl.uniprot.org/uniprot/Q2G3H6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS09515 ^@ http://purl.uniprot.org/uniprot/Q2G733 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/279238:SARO_RS16795 ^@ http://purl.uniprot.org/uniprot/Q2G331 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/279238:SARO_RS07235 ^@ http://purl.uniprot.org/uniprot/Q2G8D6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/279238:SARO_RS06540 ^@ http://purl.uniprot.org/uniprot/Q2G8S2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/279238:SARO_RS13455 ^@ http://purl.uniprot.org/uniprot/Q2G4Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS09270 ^@ http://purl.uniprot.org/uniprot/Q2G781 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/279238:SARO_RS00070 ^@ http://purl.uniprot.org/uniprot/Q2GCE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/279238:SARO_RS19220 ^@ http://purl.uniprot.org/uniprot/A4XF17 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/279238:SARO_RS07015 ^@ http://purl.uniprot.org/uniprot/Q2G8I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/279238:SARO_RS03420 ^@ http://purl.uniprot.org/uniprot/Q2GAJ1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/279238:SARO_RS04470 ^@ http://purl.uniprot.org/uniprot/Q2G9Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/279238:SARO_RS07160 ^@ http://purl.uniprot.org/uniprot/Q2G8F1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS12315 ^@ http://purl.uniprot.org/uniprot/Q2G5J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS01720 ^@ http://purl.uniprot.org/uniprot/Q2GBI2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/279238:SARO_RS09605 ^@ http://purl.uniprot.org/uniprot/Q2G717 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS00560 ^@ http://purl.uniprot.org/uniprot/Q2GC62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/279238:SARO_RS11690 ^@ http://purl.uniprot.org/uniprot/Q2G5W4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/279238:SARO_RS12770 ^@ http://purl.uniprot.org/uniprot/Q2G5A1 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/279238:SARO_RS15545 ^@ http://purl.uniprot.org/uniprot/Q2G3S7 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/279238:SARO_RS03415 ^@ http://purl.uniprot.org/uniprot/Q2GAJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/279238:SARO_RS19685 ^@ http://purl.uniprot.org/uniprot/A4XFB0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS12610 ^@ http://purl.uniprot.org/uniprot/Q2G5D3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09570 ^@ http://purl.uniprot.org/uniprot/Q2G724 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/279238:SARO_RS10195 ^@ http://purl.uniprot.org/uniprot/Q2G6Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/279238:SARO_RS04645 ^@ http://purl.uniprot.org/uniprot/Q2G9U8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/279238:SARO_RS09755 ^@ http://purl.uniprot.org/uniprot/Q2G6Y8 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/279238:SARO_RS06965 ^@ http://purl.uniprot.org/uniprot/Q2G8J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell inner membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/279238:SARO_RS05585 ^@ http://purl.uniprot.org/uniprot/Q2G9A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/279238:SARO_RS09110 ^@ http://purl.uniprot.org/uniprot/Q2G7B3 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/279238:SARO_RS10710 ^@ http://purl.uniprot.org/uniprot/Q2G6F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/279238:SARO_RS02965 ^@ http://purl.uniprot.org/uniprot/Q2GAT1 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/279238:SARO_RS18805 ^@ http://purl.uniprot.org/uniprot/A4XET5 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/279238:SARO_RS12320 ^@ http://purl.uniprot.org/uniprot/Q2G5I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS05365 ^@ http://purl.uniprot.org/uniprot/Q2G9F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS13415 ^@ http://purl.uniprot.org/uniprot/Q2G4Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS00085 ^@ http://purl.uniprot.org/uniprot/Q2GCE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/279238:SARO_RS08295 ^@ http://purl.uniprot.org/uniprot/Q2G7S9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/279238:SARO_RS00915 ^@ http://purl.uniprot.org/uniprot/Q2GBZ0 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/279238:SARO_RS10090 ^@ http://purl.uniprot.org/uniprot/Q2G6S7 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/279238:SARO_RS17920 ^@ http://purl.uniprot.org/uniprot/A4XEA8 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/279238:SARO_RS16705 ^@ http://purl.uniprot.org/uniprot/Q2G348 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/279238:SARO_RS14685 ^@ http://purl.uniprot.org/uniprot/Q2G491 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/279238:SARO_RS19260 ^@ http://purl.uniprot.org/uniprot/A4XEM2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/279238:SARO_RS10155 ^@ http://purl.uniprot.org/uniprot/Q2G6R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/279238:SARO_RS03675 ^@ http://purl.uniprot.org/uniprot/Q2GAE1 ^@ Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS06120 ^@ http://purl.uniprot.org/uniprot/Q2G904 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS09825 ^@ http://purl.uniprot.org/uniprot/Q2G6X5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/279238:SARO_RS10560 ^@ http://purl.uniprot.org/uniprot/Q2G6I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS01580 ^@ http://purl.uniprot.org/uniprot/Q2GBL0 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/279238:SARO_RS04215 ^@ http://purl.uniprot.org/uniprot/Q2GA35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS01965 ^@ http://purl.uniprot.org/uniprot/Q2GBD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/279238:SARO_RS18875 ^@ http://purl.uniprot.org/uniprot/A4XEU9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS03605 ^@ http://purl.uniprot.org/uniprot/Q2GAF5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS17595 ^@ http://purl.uniprot.org/uniprot/A4XE42 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/279238:SARO_RS06595 ^@ http://purl.uniprot.org/uniprot/Q2G8R1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/279238:SARO_RS13195 ^@ http://purl.uniprot.org/uniprot/Q2G520 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/279238:SARO_RS00630 ^@ http://purl.uniprot.org/uniprot/Q2GC47 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS19850 ^@ http://purl.uniprot.org/uniprot/A4XFE3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS11490 ^@ http://purl.uniprot.org/uniprot/Q2G604 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS12455 ^@ http://purl.uniprot.org/uniprot/Q2G5G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell inner membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/279238:SARO_RS17005 ^@ http://purl.uniprot.org/uniprot/A4XDS5 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/279238:SARO_RS08330 ^@ http://purl.uniprot.org/uniprot/Q2G7S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08670 ^@ http://purl.uniprot.org/uniprot/Q2G7K1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/279238:SARO_RS13580 ^@ http://purl.uniprot.org/uniprot/Q2G4W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/279238:SARO_RS11130 ^@ http://purl.uniprot.org/uniprot/Q2G673 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/279238:SARO_RS09510 ^@ http://purl.uniprot.org/uniprot/Q2G734 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS18055 ^@ http://purl.uniprot.org/uniprot/A4XED5 ^@ Similarity ^@ Belongs to the sulfatase family. http://togogenome.org/gene/279238:SARO_RS06045 ^@ http://purl.uniprot.org/uniprot/Q2G919 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS14770 ^@ http://purl.uniprot.org/uniprot/Q2G475 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/279238:SARO_RS08220 ^@ http://purl.uniprot.org/uniprot/Q2G7U4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/279238:SARO_RS00270 ^@ http://purl.uniprot.org/uniprot/Q2GCC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS12655 ^@ http://purl.uniprot.org/uniprot/Q2G5C4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS11265 ^@ http://purl.uniprot.org/uniprot/Q2G647 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/279238:SARO_RS17555 ^@ http://purl.uniprot.org/uniprot/A4XE34 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/279238:SARO_RS07895 ^@ http://purl.uniprot.org/uniprot/Q2G807 ^@ Cofactor ^@ Binds 2 iron ions per subunit. http://togogenome.org/gene/279238:SARO_RS16170 ^@ http://purl.uniprot.org/uniprot/Q2G3F4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane http://togogenome.org/gene/279238:SARO_RS19165 ^@ http://purl.uniprot.org/uniprot/A4XF06 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/279238:SARO_RS03520 ^@ http://purl.uniprot.org/uniprot/Q2GAH2 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/279238:SARO_RS09790 ^@ http://purl.uniprot.org/uniprot/Q2G6Y1 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/279238:SARO_RS04230 ^@ http://purl.uniprot.org/uniprot/Q2GA32 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS00025 ^@ http://purl.uniprot.org/uniprot/Q2GCF6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS02365 ^@ http://purl.uniprot.org/uniprot/Q2GB53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS11875 ^@ http://purl.uniprot.org/uniprot/Q2G5S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS05030 ^@ http://purl.uniprot.org/uniprot/Q2G9M1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/279238:SARO_RS14155 ^@ http://purl.uniprot.org/uniprot/Q2G4J7 ^@ Cofactor|||Function ^@ Alkaline phosphatase with broad substrate specificity.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/279238:SARO_RS16855 ^@ http://purl.uniprot.org/uniprot/Q2G319 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/279238:SARO_RS19050 ^@ http://purl.uniprot.org/uniprot/A4XEY3 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/279238:SARO_RS04510 ^@ http://purl.uniprot.org/uniprot/Q2G9X6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/279238:SARO_RS02870 ^@ http://purl.uniprot.org/uniprot/Q2GAV1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/279238:SARO_RS12085 ^@ http://purl.uniprot.org/uniprot/Q2G5N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/279238:SARO_RS17030 ^@ http://purl.uniprot.org/uniprot/A4XDS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08490 ^@ http://purl.uniprot.org/uniprot/Q2G7N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/279238:SARO_RS14175 ^@ http://purl.uniprot.org/uniprot/Q2G4J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS19755 ^@ http://purl.uniprot.org/uniprot/A4XFC4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS13065 ^@ http://purl.uniprot.org/uniprot/Q2G545 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/279238:SARO_RS18825 ^@ http://purl.uniprot.org/uniprot/A4XET9 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/279238:SARO_RS04320 ^@ http://purl.uniprot.org/uniprot/Q2GA15 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/279238:SARO_RS00700 ^@ http://purl.uniprot.org/uniprot/Q2GC33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/279238:SARO_RS03770 ^@ http://purl.uniprot.org/uniprot/Q2GAC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS04690 ^@ http://purl.uniprot.org/uniprot/Q2G9T9 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family. AstD subfamily.|||Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. http://togogenome.org/gene/279238:SARO_RS04585 ^@ http://purl.uniprot.org/uniprot/Q2G9W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS02250 ^@ http://purl.uniprot.org/uniprot/Q2GB76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS11285 ^@ http://purl.uniprot.org/uniprot/Q2G643 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS06465 ^@ http://purl.uniprot.org/uniprot/Q2G8T7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/279238:SARO_RS01100 ^@ http://purl.uniprot.org/uniprot/Q2GBV5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS07730 ^@ http://purl.uniprot.org/uniprot/Q2G839 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS16165 ^@ http://purl.uniprot.org/uniprot/Q2G3F5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS12230 ^@ http://purl.uniprot.org/uniprot/Q2G5K7 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/279238:SARO_RS07285 ^@ http://purl.uniprot.org/uniprot/Q2G8C7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/279238:SARO_RS05575 ^@ http://purl.uniprot.org/uniprot/Q2G9B0 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/279238:SARO_RS19995 ^@ http://purl.uniprot.org/uniprot/A4XFH2 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/279238:SARO_RS13470 ^@ http://purl.uniprot.org/uniprot/Q2G4Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/279238:SARO_RS10635 ^@ http://purl.uniprot.org/uniprot/Q2G6G9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/279238:SARO_RS04210 ^@ http://purl.uniprot.org/uniprot/Q2GA36 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/279238:SARO_RS03045 ^@ http://purl.uniprot.org/uniprot/Q2GAR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/279238:SARO_RS19805 ^@ http://purl.uniprot.org/uniprot/A4XFD4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00505 ^@ http://purl.uniprot.org/uniprot/Q2GC73 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/279238:SARO_RS08415 ^@ http://purl.uniprot.org/uniprot/Q2G7Q4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/279238:SARO_RS05310 ^@ http://purl.uniprot.org/uniprot/Q2G9G4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/279238:SARO_RS05505 ^@ http://purl.uniprot.org/uniprot/Q2G9C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS18955 ^@ http://purl.uniprot.org/uniprot/A4XEW5 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/279238:SARO_RS13040 ^@ http://purl.uniprot.org/uniprot/Q2G550 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/279238:SARO_RS07995 ^@ http://purl.uniprot.org/uniprot/Q2G7Y8 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/279238:SARO_RS02220 ^@ http://purl.uniprot.org/uniprot/Q2GB82 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS12940 ^@ http://purl.uniprot.org/uniprot/Q2G570 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/279238:SARO_RS00445 ^@ http://purl.uniprot.org/uniprot/Q2GC85 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS00855 ^@ http://purl.uniprot.org/uniprot/Q2GC02 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/279238:SARO_RS06655 ^@ http://purl.uniprot.org/uniprot/Q2G8P9 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/279238:SARO_RS04695 ^@ http://purl.uniprot.org/uniprot/Q2G9T8 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/279238:SARO_RS10205 ^@ http://purl.uniprot.org/uniprot/Q2G6Q5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/279238:SARO_RS00500 ^@ http://purl.uniprot.org/uniprot/Q2GC74 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/279238:SARO_RS09960 ^@ http://purl.uniprot.org/uniprot/Q2G6V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/279238:SARO_RS14440 ^@ http://purl.uniprot.org/uniprot/Q2G4E0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS12795 ^@ http://purl.uniprot.org/uniprot/Q2G596 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS03445 ^@ http://purl.uniprot.org/uniprot/Q2GAI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/279238:SARO_RS14435 ^@ http://purl.uniprot.org/uniprot/Q2G4E1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/279238:SARO_RS07925 ^@ http://purl.uniprot.org/uniprot/Q2G801 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/279238:SARO_RS05950 ^@ http://purl.uniprot.org/uniprot/Q2G936 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/279238:SARO_RS10075 ^@ http://purl.uniprot.org/uniprot/Q2G6T0 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/279238:SARO_RS10275 ^@ http://purl.uniprot.org/uniprot/Q2G6P1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/279238:SARO_RS04950 ^@ http://purl.uniprot.org/uniprot/Q2G9N7 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/279238:SARO_RS06265 ^@ http://purl.uniprot.org/uniprot/Q2G8X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/279238:SARO_RS15725 ^@ http://purl.uniprot.org/uniprot/Q2G3P2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/279238:SARO_RS08425 ^@ http://purl.uniprot.org/uniprot/Q2G7Q2 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/279238:SARO_RS04000 ^@ http://purl.uniprot.org/uniprot/Q2GA77 ^@ Similarity ^@ Belongs to the UPF0311 family. http://togogenome.org/gene/279238:SARO_RS08315 ^@ http://purl.uniprot.org/uniprot/Q2G7S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/279238:SARO_RS02235 ^@ http://purl.uniprot.org/uniprot/Q2GB79 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/279238:SARO_RS04890 ^@ http://purl.uniprot.org/uniprot/Q2G9P9 ^@ Similarity ^@ Belongs to the UPF0053 family. Hemolysin C subfamily. http://togogenome.org/gene/279238:SARO_RS12520 ^@ http://purl.uniprot.org/uniprot/Q2G5F0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS01450 ^@ http://purl.uniprot.org/uniprot/Q2GBN6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS00670 ^@ http://purl.uniprot.org/uniprot/Q2GC39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/279238:SARO_RS04160 ^@ http://purl.uniprot.org/uniprot/Q2GA46 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/279238:SARO_RS14675 ^@ http://purl.uniprot.org/uniprot/Q2G493 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/279238:SARO_RS01130 ^@ http://purl.uniprot.org/uniprot/Q2GBU9 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/279238:SARO_RS03425 ^@ http://purl.uniprot.org/uniprot/Q2GAJ0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/279238:SARO_RS00285 ^@ http://purl.uniprot.org/uniprot/Q2GCB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/279238:SARO_RS12290 ^@ http://purl.uniprot.org/uniprot/Q2G5J5 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS01145 ^@ http://purl.uniprot.org/uniprot/Q2GBU6 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family. DsbA subfamily.|||May be required for disulfide bond formation in some proteins. http://togogenome.org/gene/279238:SARO_RS04170 ^@ http://purl.uniprot.org/uniprot/Q2GA44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/279238:SARO_RS05170 ^@ http://purl.uniprot.org/uniprot/Q2G9J1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS01495 ^@ http://purl.uniprot.org/uniprot/Q2GBM7 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/279238:SARO_RS04205 ^@ http://purl.uniprot.org/uniprot/Q2GA37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS19660 ^@ http://purl.uniprot.org/uniprot/A4XFA5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS13620 ^@ http://purl.uniprot.org/uniprot/Q2G4V4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/279238:SARO_RS11555 ^@ http://purl.uniprot.org/uniprot/Q2G5Z1 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/279238:SARO_RS09720 ^@ http://purl.uniprot.org/uniprot/Q2G6Z4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/279238:SARO_RS09245 ^@ http://purl.uniprot.org/uniprot/Q2G786 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/279238:SARO_RS07685 ^@ http://purl.uniprot.org/uniprot/Q2G849 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS05890 ^@ http://purl.uniprot.org/uniprot/Q2G947 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/279238:SARO_RS16425 ^@ http://purl.uniprot.org/uniprot/Q2G3A3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/279238:SARO_RS02925 ^@ http://purl.uniprot.org/uniprot/Q2GAT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/279238:SARO_RS19870 ^@ http://purl.uniprot.org/uniprot/A4XFE7 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/279238:SARO_RS12905 ^@ http://purl.uniprot.org/uniprot/Q2G577 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS05530 ^@ http://purl.uniprot.org/uniprot/Q2G9B9 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/279238:SARO_RS01555 ^@ http://purl.uniprot.org/uniprot/Q2GBL5 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/279238:SARO_RS01635 ^@ http://purl.uniprot.org/uniprot/Q2GBJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell inner membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate. http://togogenome.org/gene/279238:SARO_RS01565 ^@ http://purl.uniprot.org/uniprot/Q2GBL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/279238:SARO_RS14555 ^@ http://purl.uniprot.org/uniprot/Q2G4B7 ^@ Cofactor|||Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family.|||Binds 1 Ca(2+) ion per subunit.|||Binds 1 PQQ group per subunit.|||Binds 1 heme c group per subunit. http://togogenome.org/gene/279238:SARO_RS13125 ^@ http://purl.uniprot.org/uniprot/Q2G534 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS19825 ^@ http://purl.uniprot.org/uniprot/A4XFD8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/279238:SARO_RS16535 ^@ http://purl.uniprot.org/uniprot/Q2G380 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/279238:SARO_RS06665 ^@ http://purl.uniprot.org/uniprot/Q2G8P7 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/279238:SARO_RS10450 ^@ http://purl.uniprot.org/uniprot/Q2G6K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/279238:SARO_RS11295 ^@ http://purl.uniprot.org/uniprot/Q2G641 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/279238:SARO_RS12715 ^@ http://purl.uniprot.org/uniprot/Q2G5B2 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/279238:SARO_RS02480 ^@ http://purl.uniprot.org/uniprot/Q2GB30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS11965 ^@ http://purl.uniprot.org/uniprot/Q2G5Q9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS06590 ^@ http://purl.uniprot.org/uniprot/Q2G8R2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/279238:SARO_RS06280 ^@ http://purl.uniprot.org/uniprot/Q2G8X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/279238:SARO_RS00815 ^@ http://purl.uniprot.org/uniprot/Q2GC09 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/279238:SARO_RS09805 ^@ http://purl.uniprot.org/uniprot/Q2G6X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS05010 ^@ http://purl.uniprot.org/uniprot/Q2G9M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/279238:SARO_RS11280 ^@ http://purl.uniprot.org/uniprot/Q2G644 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/279238:SARO_RS12070 ^@ http://purl.uniprot.org/uniprot/Q2G5N8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/279238:SARO_RS01430 ^@ http://purl.uniprot.org/uniprot/Q2GBP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06255 ^@ http://purl.uniprot.org/uniprot/Q2G8X9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/279238:SARO_RS17990 ^@ http://purl.uniprot.org/uniprot/A4XEC2 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/279238:SARO_RS11185 ^@ http://purl.uniprot.org/uniprot/Q2G662 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/279238:SARO_RS09875 ^@ http://purl.uniprot.org/uniprot/Q2G6W5 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/279238:SARO_RS14295 ^@ http://purl.uniprot.org/uniprot/Q2G4G9 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/279238:SARO_RS09055 ^@ http://purl.uniprot.org/uniprot/Q2G7C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS10035 ^@ http://purl.uniprot.org/uniprot/Q2G6T8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/279238:SARO_RS10220 ^@ http://purl.uniprot.org/uniprot/Q2G6Q2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/279238:SARO_RS12080 ^@ http://purl.uniprot.org/uniprot/Q2G5N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/279238:SARO_RS06400 ^@ http://purl.uniprot.org/uniprot/Q2G8V0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS06470 ^@ http://purl.uniprot.org/uniprot/Q2G8T6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/279238:SARO_RS07465 ^@ http://purl.uniprot.org/uniprot/Q2G892 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS08945 ^@ http://purl.uniprot.org/uniprot/Q2G7E6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/279238:SARO_RS06660 ^@ http://purl.uniprot.org/uniprot/Q2G8P8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/279238:SARO_RS00835 ^@ http://purl.uniprot.org/uniprot/Q2GC06 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS20020 ^@ http://purl.uniprot.org/uniprot/A4XFH7 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/279238:SARO_RS14205 ^@ http://purl.uniprot.org/uniprot/Q2G4I7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/279238:SARO_RS10830 ^@ http://purl.uniprot.org/uniprot/Q2G6D3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/279238:SARO_RS16090 ^@ http://purl.uniprot.org/uniprot/Q2G3H0 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/279238:SARO_RS09630 ^@ http://purl.uniprot.org/uniprot/Q2G712 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/279238:SARO_RS12500 ^@ http://purl.uniprot.org/uniprot/Q2G5F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/279238:SARO_RS00725 ^@ http://purl.uniprot.org/uniprot/Q2GC28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer. http://togogenome.org/gene/279238:SARO_RS17295 ^@ http://purl.uniprot.org/uniprot/A4XDY0 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the reversible phosphorylation of pyruvate and phosphate. http://togogenome.org/gene/279238:SARO_RS02885 ^@ http://purl.uniprot.org/uniprot/Q2GAU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/279238:SARO_RS18280 ^@ http://purl.uniprot.org/uniprot/A4XEI0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/279238:SARO_RS00590 ^@ http://purl.uniprot.org/uniprot/Q2GC56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/279238:SARO_RS00390 ^@ http://purl.uniprot.org/uniprot/Q2GC97 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/279238:SARO_RS14430 ^@ http://purl.uniprot.org/uniprot/Q2G4E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Could be part of an ABC transporter complex.|||Membrane http://togogenome.org/gene/279238:SARO_RS14135 ^@ http://purl.uniprot.org/uniprot/Q2G4K1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/279238:SARO_RS17885 ^@ http://purl.uniprot.org/uniprot/A4XEA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/279238:SARO_RS06325 ^@ http://purl.uniprot.org/uniprot/Q2G8W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/279238:SARO_RS11220 ^@ http://purl.uniprot.org/uniprot/Q2G655 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/279238:SARO_RS12755 ^@ http://purl.uniprot.org/uniprot/Q2G5A4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/279238:SARO_RS07740 ^@ http://purl.uniprot.org/uniprot/Q2G838 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/279238:SARO_RS18540 ^@ http://purl.uniprot.org/uniprot/A4XEN2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/279238:SARO_RS14925 ^@ http://purl.uniprot.org/uniprot/Q2G444 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/279238:SARO_RS06550 ^@ http://purl.uniprot.org/uniprot/Q2G8S0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/279238:SARO_RS08840 ^@ http://purl.uniprot.org/uniprot/Q2G7G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/279238:SARO_RS11605 ^@ http://purl.uniprot.org/uniprot/Q2G5Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/279238:SARO_RS07940 ^@ http://purl.uniprot.org/uniprot/Q2G7Z9 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/279238:SARO_RS16435 ^@ http://purl.uniprot.org/uniprot/Q2G3A1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/279238:SARO_RS11340 ^@ http://purl.uniprot.org/uniprot/Q2G632 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/279238:SARO_RS19250 ^@ http://purl.uniprot.org/uniprot/A4XF23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).|||Homotetramer. http://togogenome.org/gene/279238:SARO_RS00045 ^@ http://purl.uniprot.org/uniprot/Q2GCF2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/279238:SARO_RS06865 ^@ http://purl.uniprot.org/uniprot/Q2G8L0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/279238:SARO_RS06795 ^@ http://purl.uniprot.org/uniprot/Q2G8M3 ^@ Function ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. http://togogenome.org/gene/279238:SARO_RS14185 ^@ http://purl.uniprot.org/uniprot/Q2G4J1 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family.