http://togogenome.org/gene/298654:FRAEUI1C_RS26450 ^@ http://purl.uniprot.org/uniprot/E3J8B8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS12830 ^@ http://purl.uniprot.org/uniprot/E3J3X6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27540 ^@ http://purl.uniprot.org/uniprot/E3JC72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS30815 ^@ http://purl.uniprot.org/uniprot/E3J388 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/298654:FRAEUI1C_RS26915 ^@ http://purl.uniprot.org/uniprot/E3JAR5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30945 ^@ http://purl.uniprot.org/uniprot/E3J3B4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/298654:FRAEUI1C_RS25445 ^@ http://purl.uniprot.org/uniprot/E3J5M9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16420 ^@ http://purl.uniprot.org/uniprot/E3IVF1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS37930 ^@ http://purl.uniprot.org/uniprot/E3IZX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS30875 ^@ http://purl.uniprot.org/uniprot/E3J3A0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/298654:FRAEUI1C_RS24260 ^@ http://purl.uniprot.org/uniprot/E3J1S1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/298654:FRAEUI1C_RS15920 ^@ http://purl.uniprot.org/uniprot/E3IU20 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11270 ^@ http://purl.uniprot.org/uniprot/E3IZ22 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS00860 ^@ http://purl.uniprot.org/uniprot/E3J4T8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS31000 ^@ http://purl.uniprot.org/uniprot/E3J3C5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS18945 ^@ http://purl.uniprot.org/uniprot/E3J445 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03970 ^@ http://purl.uniprot.org/uniprot/E3IUY9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS08125 ^@ http://purl.uniprot.org/uniprot/E3J8W4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05205 ^@ http://purl.uniprot.org/uniprot/E3IYX1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/298654:FRAEUI1C_RS16855 ^@ http://purl.uniprot.org/uniprot/E3IWS1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12170 ^@ http://purl.uniprot.org/uniprot/E3J1F6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05025 ^@ http://purl.uniprot.org/uniprot/E3IYT7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS11470 ^@ http://purl.uniprot.org/uniprot/E3J062 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS15085 ^@ http://purl.uniprot.org/uniprot/E3JBN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16120 ^@ http://purl.uniprot.org/uniprot/E3IV90 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02745 ^@ http://purl.uniprot.org/uniprot/E3JBA1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS02245 ^@ http://purl.uniprot.org/uniprot/E3J9X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15755 ^@ http://purl.uniprot.org/uniprot/E3ITZ2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS35570 ^@ http://purl.uniprot.org/uniprot/E3IZU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03075 ^@ http://purl.uniprot.org/uniprot/E3JCK1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS03070 ^@ http://purl.uniprot.org/uniprot/E3JCK0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/298654:FRAEUI1C_RS13465 ^@ http://purl.uniprot.org/uniprot/E3J6F6 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/298654:FRAEUI1C_RS22215 ^@ http://purl.uniprot.org/uniprot/E3IUD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35195 ^@ http://purl.uniprot.org/uniprot/E3IYI7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS01835 ^@ http://purl.uniprot.org/uniprot/E3J8K8 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/298654:FRAEUI1C_RS00625 ^@ http://purl.uniprot.org/uniprot/E3J3K9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/298654:FRAEUI1C_RS31390 ^@ http://purl.uniprot.org/uniprot/E3J4N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/298654:FRAEUI1C_RS24460 ^@ http://purl.uniprot.org/uniprot/E3J1V9 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/298654:FRAEUI1C_RS04135 ^@ http://purl.uniprot.org/uniprot/E3IW60 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/298654:FRAEUI1C_RS10025 ^@ http://purl.uniprot.org/uniprot/E3IV42 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS05685 ^@ http://purl.uniprot.org/uniprot/E3J130 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27290 ^@ http://purl.uniprot.org/uniprot/E3JC22 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19690 ^@ http://purl.uniprot.org/uniprot/E3J6P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08720 ^@ http://purl.uniprot.org/uniprot/E3JBD8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS23585 ^@ http://purl.uniprot.org/uniprot/E3IZH4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/298654:FRAEUI1C_RS28595 ^@ http://purl.uniprot.org/uniprot/E3IVT5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS10805 ^@ http://purl.uniprot.org/uniprot/E3IXQ1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS14090 ^@ http://purl.uniprot.org/uniprot/E3J7V6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32295 ^@ http://purl.uniprot.org/uniprot/E3IXH2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/298654:FRAEUI1C_RS11680 ^@ http://purl.uniprot.org/uniprot/E3J0A1 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31730 ^@ http://purl.uniprot.org/uniprot/E3J5Y2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/298654:FRAEUI1C_RS23150 ^@ http://purl.uniprot.org/uniprot/E3IY63 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/298654:FRAEUI1C_RS34855 ^@ http://purl.uniprot.org/uniprot/E3IX92 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22910 ^@ http://purl.uniprot.org/uniprot/E3IWZ0 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32480 ^@ http://purl.uniprot.org/uniprot/E3J8I0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/298654:FRAEUI1C_RS34330 ^@ http://purl.uniprot.org/uniprot/E3IUS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19725 ^@ http://purl.uniprot.org/uniprot/E3J6Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08265 ^@ http://purl.uniprot.org/uniprot/E3J8Z2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/298654:FRAEUI1C_RS27800 ^@ http://purl.uniprot.org/uniprot/E3JDE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS34080 ^@ http://purl.uniprot.org/uniprot/E3IUM0 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/298654:FRAEUI1C_RS00285 ^@ http://purl.uniprot.org/uniprot/E3J3E3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/298654:FRAEUI1C_RS17730 ^@ http://purl.uniprot.org/uniprot/E3J0F1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/298654:FRAEUI1C_RS05470 ^@ http://purl.uniprot.org/uniprot/E3J027 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS24195 ^@ http://purl.uniprot.org/uniprot/E3J1Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03545 ^@ http://purl.uniprot.org/uniprot/E3ITN0 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30470 ^@ http://purl.uniprot.org/uniprot/E3J210 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. http://togogenome.org/gene/298654:FRAEUI1C_RS29830 ^@ http://purl.uniprot.org/uniprot/E3IZS0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS05365 ^@ http://purl.uniprot.org/uniprot/E3J005 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS35725 ^@ http://purl.uniprot.org/uniprot/E3IZX2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS15660 ^@ http://purl.uniprot.org/uniprot/E3JD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21730 ^@ http://purl.uniprot.org/uniprot/E3JD94 ^@ Similarity ^@ Belongs to the mycobacterial A85 antigen family. http://togogenome.org/gene/298654:FRAEUI1C_RS01815 ^@ http://purl.uniprot.org/uniprot/E3J8K4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26095 ^@ http://purl.uniprot.org/uniprot/E3J847 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03295 ^@ http://purl.uniprot.org/uniprot/E3ITI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10410 ^@ http://purl.uniprot.org/uniprot/E3IWF6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31765 ^@ http://purl.uniprot.org/uniprot/E3J5Z0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/298654:FRAEUI1C_RS36405 ^@ http://purl.uniprot.org/uniprot/E3IZC8 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28395 ^@ http://purl.uniprot.org/uniprot/E3IVP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15845 ^@ http://purl.uniprot.org/uniprot/E3IU05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS24885 ^@ http://purl.uniprot.org/uniprot/E3J353 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14865 ^@ http://purl.uniprot.org/uniprot/E3JAG0 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/298654:FRAEUI1C_RS24065 ^@ http://purl.uniprot.org/uniprot/E3J0S1 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/298654:FRAEUI1C_RS19720 ^@ http://purl.uniprot.org/uniprot/E3J6Q4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31370 ^@ http://purl.uniprot.org/uniprot/E3J4M9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/298654:FRAEUI1C_RS35145 ^@ http://purl.uniprot.org/uniprot/E3IXE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS33885 ^@ http://purl.uniprot.org/uniprot/E3JDM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04740 ^@ http://purl.uniprot.org/uniprot/E3IXK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS31090 ^@ http://purl.uniprot.org/uniprot/E3J4H3 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/298654:FRAEUI1C_RS15885 ^@ http://purl.uniprot.org/uniprot/E3IU13 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/298654:FRAEUI1C_RS19460 ^@ http://purl.uniprot.org/uniprot/E3J5I3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS22025 ^@ http://purl.uniprot.org/uniprot/E3IU95 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05520 ^@ http://purl.uniprot.org/uniprot/E3J037 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/298654:FRAEUI1C_RS01605 ^@ http://purl.uniprot.org/uniprot/E3J7D2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/298654:FRAEUI1C_RS12420 ^@ http://purl.uniprot.org/uniprot/E3J2L4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS28840 ^@ http://purl.uniprot.org/uniprot/E3IX15 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/298654:FRAEUI1C_RS29795 ^@ http://purl.uniprot.org/uniprot/E3IZR3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS32235 ^@ http://purl.uniprot.org/uniprot/E3J8D2 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/298654:FRAEUI1C_RS13610 ^@ http://purl.uniprot.org/uniprot/E3J6I8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS19130 ^@ http://purl.uniprot.org/uniprot/E3J482 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24150 ^@ http://purl.uniprot.org/uniprot/E3J1P9 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/298654:FRAEUI1C_RS06160 ^@ http://purl.uniprot.org/uniprot/E3J2D1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15215 ^@ http://purl.uniprot.org/uniprot/E3JBQ9 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/298654:FRAEUI1C_RS01230 ^@ http://purl.uniprot.org/uniprot/E3J641 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS16785 ^@ http://purl.uniprot.org/uniprot/E3IWQ7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30480 ^@ http://purl.uniprot.org/uniprot/E3J212 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06220 ^@ http://purl.uniprot.org/uniprot/E3J2E3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 3-HAO family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. http://togogenome.org/gene/298654:FRAEUI1C_RS05935 ^@ http://purl.uniprot.org/uniprot/E3J180 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS29875 ^@ http://purl.uniprot.org/uniprot/E3IZS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/298654:FRAEUI1C_RS16665 ^@ http://purl.uniprot.org/uniprot/E3IWN4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS04705 ^@ http://purl.uniprot.org/uniprot/E3IXJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS16845 ^@ http://purl.uniprot.org/uniprot/E3IWR9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24770 ^@ http://purl.uniprot.org/uniprot/E3J329 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/298654:FRAEUI1C_RS35180 ^@ http://purl.uniprot.org/uniprot/E3IYI4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/298654:FRAEUI1C_RS21510 ^@ http://purl.uniprot.org/uniprot/E3JD49 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS35550 ^@ http://purl.uniprot.org/uniprot/E3IZT7 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS30895 ^@ http://purl.uniprot.org/uniprot/E3J3A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/298654:FRAEUI1C_RS09295 ^@ http://purl.uniprot.org/uniprot/E3JCT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18805 ^@ http://purl.uniprot.org/uniprot/E3J416 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28275 ^@ http://purl.uniprot.org/uniprot/E3IUI8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/298654:FRAEUI1C_RS32420 ^@ http://purl.uniprot.org/uniprot/E3J8G8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28125 ^@ http://purl.uniprot.org/uniprot/E3IUF9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS41335 ^@ http://purl.uniprot.org/uniprot/E3J246 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/298654:FRAEUI1C_RS26070 ^@ http://purl.uniprot.org/uniprot/E3J715 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24300 ^@ http://purl.uniprot.org/uniprot/E3J1S9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS33050 ^@ http://purl.uniprot.org/uniprot/E3JB02 ^@ Function|||Similarity ^@ Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine. http://togogenome.org/gene/298654:FRAEUI1C_RS30435 ^@ http://purl.uniprot.org/uniprot/E3J203 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS29400 ^@ http://purl.uniprot.org/uniprot/E3IYF7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05410 ^@ http://purl.uniprot.org/uniprot/E3J014 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/298654:FRAEUI1C_RS11690 ^@ http://purl.uniprot.org/uniprot/E3J0A3 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23290 ^@ http://purl.uniprot.org/uniprot/E3IY90 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/298654:FRAEUI1C_RS08700 ^@ http://purl.uniprot.org/uniprot/E3JBD4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/298654:FRAEUI1C_RS02380 ^@ http://purl.uniprot.org/uniprot/E3J9Z8 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS20200 ^@ http://purl.uniprot.org/uniprot/E3J824 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS08370 ^@ http://purl.uniprot.org/uniprot/E3JA44 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS08380 ^@ http://purl.uniprot.org/uniprot/E3JA46 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/298654:FRAEUI1C_RS11220 ^@ http://purl.uniprot.org/uniprot/E3IZ12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05795 ^@ http://purl.uniprot.org/uniprot/E3J152 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23945 ^@ http://purl.uniprot.org/uniprot/E3J0P7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome http://togogenome.org/gene/298654:FRAEUI1C_RS13435 ^@ http://purl.uniprot.org/uniprot/E3J6F0 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/298654:FRAEUI1C_RS08915 ^@ http://purl.uniprot.org/uniprot/E3JBH7 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS01100 ^@ http://purl.uniprot.org/uniprot/E3J614 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/298654:FRAEUI1C_RS24845 ^@ http://purl.uniprot.org/uniprot/E3J345 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS08845 ^@ http://purl.uniprot.org/uniprot/E3JBG3 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/298654:FRAEUI1C_RS20805 ^@ http://purl.uniprot.org/uniprot/E3JAK0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31145 ^@ http://purl.uniprot.org/uniprot/E3J4I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS19445 ^@ http://purl.uniprot.org/uniprot/E3J5I0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16110 ^@ http://purl.uniprot.org/uniprot/E3IU59 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27040 ^@ http://purl.uniprot.org/uniprot/E3JAU0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10975 ^@ http://purl.uniprot.org/uniprot/E3IXT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS30905 ^@ http://purl.uniprot.org/uniprot/E3J3A6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/298654:FRAEUI1C_RS27100 ^@ http://purl.uniprot.org/uniprot/E3JAV2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS24860 ^@ http://purl.uniprot.org/uniprot/E3J348 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS03460 ^@ http://purl.uniprot.org/uniprot/E3ITL2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/298654:FRAEUI1C_RS28390 ^@ http://purl.uniprot.org/uniprot/E3IUL1 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS35095 ^@ http://purl.uniprot.org/uniprot/E3IXD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29955 ^@ http://purl.uniprot.org/uniprot/E3J0U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19645 ^@ http://purl.uniprot.org/uniprot/E3J6N9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30920 ^@ http://purl.uniprot.org/uniprot/E3J3A9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/298654:FRAEUI1C_RS12535 ^@ http://purl.uniprot.org/uniprot/E3J2N6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02155 ^@ http://purl.uniprot.org/uniprot/E3J9V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05775 ^@ http://purl.uniprot.org/uniprot/E3J148 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/298654:FRAEUI1C_RS02700 ^@ http://purl.uniprot.org/uniprot/E3JB94 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/298654:FRAEUI1C_RS36890 ^@ http://purl.uniprot.org/uniprot/E3J9Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33385 ^@ http://purl.uniprot.org/uniprot/E3JCA2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS26950 ^@ http://purl.uniprot.org/uniprot/E3JAS2 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS29080 ^@ http://purl.uniprot.org/uniprot/E3IX67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/298654:FRAEUI1C_RS05450 ^@ http://purl.uniprot.org/uniprot/E3J022 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/298654:FRAEUI1C_RS28100 ^@ http://purl.uniprot.org/uniprot/E3IUF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08205 ^@ http://purl.uniprot.org/uniprot/E3J8Y0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31720 ^@ http://purl.uniprot.org/uniprot/E3J5Y0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/298654:FRAEUI1C_RS18820 ^@ http://purl.uniprot.org/uniprot/E3J419 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06585 ^@ http://purl.uniprot.org/uniprot/E3J3P8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/298654:FRAEUI1C_RS11830 ^@ http://purl.uniprot.org/uniprot/E3J0D0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS07345 ^@ http://purl.uniprot.org/uniprot/E3J6B0 ^@ Similarity ^@ Belongs to the LuxC family. http://togogenome.org/gene/298654:FRAEUI1C_RS31005 ^@ http://purl.uniprot.org/uniprot/E3J3C6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/298654:FRAEUI1C_RS25385 ^@ http://purl.uniprot.org/uniprot/E3J5L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09250 ^@ http://purl.uniprot.org/uniprot/E3JCS2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS09745 ^@ http://purl.uniprot.org/uniprot/E3ITW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/298654:FRAEUI1C_RS12540 ^@ http://purl.uniprot.org/uniprot/E3J2N7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS28765 ^@ http://purl.uniprot.org/uniprot/E3IVX0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20945 ^@ http://purl.uniprot.org/uniprot/E3JAM8 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/298654:FRAEUI1C_RS15335 ^@ http://purl.uniprot.org/uniprot/E3JBT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04340 ^@ http://purl.uniprot.org/uniprot/E3IWA2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14320 ^@ http://purl.uniprot.org/uniprot/E3J927 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11225 ^@ http://purl.uniprot.org/uniprot/E3IZ13 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19555 ^@ http://purl.uniprot.org/uniprot/E3J6M2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS10945 ^@ http://purl.uniprot.org/uniprot/E3IXS9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/298654:FRAEUI1C_RS05705 ^@ http://purl.uniprot.org/uniprot/E3J134 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/298654:FRAEUI1C_RS27115 ^@ http://purl.uniprot.org/uniprot/E3JAV5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08515 ^@ http://purl.uniprot.org/uniprot/E3JA74 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/298654:FRAEUI1C_RS12160 ^@ http://purl.uniprot.org/uniprot/E3J1F4 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/298654:FRAEUI1C_RS05045 ^@ http://purl.uniprot.org/uniprot/E3IYU1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS18490 ^@ http://purl.uniprot.org/uniprot/E3J2S2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS30800 ^@ http://purl.uniprot.org/uniprot/E3J385 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/298654:FRAEUI1C_RS15190 ^@ http://purl.uniprot.org/uniprot/E3JBQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/298654:FRAEUI1C_RS32900 ^@ http://purl.uniprot.org/uniprot/E3J9T9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS01335 ^@ http://purl.uniprot.org/uniprot/E3J661 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14405 ^@ http://purl.uniprot.org/uniprot/E3J943 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27940 ^@ http://purl.uniprot.org/uniprot/E3JDH3 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/298654:FRAEUI1C_RS09795 ^@ http://purl.uniprot.org/uniprot/E3ITX0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/298654:FRAEUI1C_RS28440 ^@ http://purl.uniprot.org/uniprot/E3IVQ4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS02325 ^@ http://purl.uniprot.org/uniprot/E3J9Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21265 ^@ http://purl.uniprot.org/uniprot/E3JBX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12395 ^@ http://purl.uniprot.org/uniprot/E3J2K9 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/298654:FRAEUI1C_RS26220 ^@ http://purl.uniprot.org/uniprot/E3J872 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05700 ^@ http://purl.uniprot.org/uniprot/E3J133 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS13820 ^@ http://purl.uniprot.org/uniprot/E3J7Q2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21740 ^@ http://purl.uniprot.org/uniprot/E3JD96 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/298654:FRAEUI1C_RS24680 ^@ http://purl.uniprot.org/uniprot/E3J311 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/298654:FRAEUI1C_RS05650 ^@ http://purl.uniprot.org/uniprot/E3J123 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS15915 ^@ http://purl.uniprot.org/uniprot/E3IU19 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS16050 ^@ http://purl.uniprot.org/uniprot/E3IU47 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS17595 ^@ http://purl.uniprot.org/uniprot/E3IZC5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31350 ^@ http://purl.uniprot.org/uniprot/E3J4M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS39065 ^@ http://purl.uniprot.org/uniprot/E3J427 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/298654:FRAEUI1C_RS24220 ^@ http://purl.uniprot.org/uniprot/E3J1R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/298654:FRAEUI1C_RS37375 ^@ http://purl.uniprot.org/uniprot/E3IZY8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/298654:FRAEUI1C_RS01065 ^@ http://purl.uniprot.org/uniprot/E3J607 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07820 ^@ http://purl.uniprot.org/uniprot/E3J7M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS02400 ^@ http://purl.uniprot.org/uniprot/E3JA02 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS13030 ^@ http://purl.uniprot.org/uniprot/E3J550 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS34890 ^@ http://purl.uniprot.org/uniprot/E3IX99 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/298654:FRAEUI1C_RS21365 ^@ http://purl.uniprot.org/uniprot/E3JBZ4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34685 ^@ http://purl.uniprot.org/uniprot/E3IW29 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/298654:FRAEUI1C_RS16180 ^@ http://purl.uniprot.org/uniprot/E3IVA2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS14200 ^@ http://purl.uniprot.org/uniprot/E3J903 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS13050 ^@ http://purl.uniprot.org/uniprot/E3J554 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS13880 ^@ http://purl.uniprot.org/uniprot/E3J7R4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09465 ^@ http://purl.uniprot.org/uniprot/E3JCW4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS10730 ^@ http://purl.uniprot.org/uniprot/E3IXN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28720 ^@ http://purl.uniprot.org/uniprot/E3IVW1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS37245 ^@ http://purl.uniprot.org/uniprot/E3IUI0 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/298654:FRAEUI1C_RS16115 ^@ http://purl.uniprot.org/uniprot/E3IV89 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15840 ^@ http://purl.uniprot.org/uniprot/E3IU04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00695 ^@ http://purl.uniprot.org/uniprot/E3J4Q5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/298654:FRAEUI1C_RS16010 ^@ http://purl.uniprot.org/uniprot/E3IU38 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS23010 ^@ http://purl.uniprot.org/uniprot/E3IY36 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25095 ^@ http://purl.uniprot.org/uniprot/E3J4C7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS37720 ^@ http://purl.uniprot.org/uniprot/E3J6Y8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30840 ^@ http://purl.uniprot.org/uniprot/E3J393 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS10855 ^@ http://purl.uniprot.org/uniprot/E3IXR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26980 ^@ http://purl.uniprot.org/uniprot/E3JAS8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS21700 ^@ http://purl.uniprot.org/uniprot/E3JD88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12570 ^@ http://purl.uniprot.org/uniprot/E3J2P3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10080 ^@ http://purl.uniprot.org/uniprot/E3IV53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28745 ^@ http://purl.uniprot.org/uniprot/E3IVW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35245 ^@ http://purl.uniprot.org/uniprot/E3IYJ7 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/298654:FRAEUI1C_RS05800 ^@ http://purl.uniprot.org/uniprot/E3J153 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS02845 ^@ http://purl.uniprot.org/uniprot/E3JBB9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS21950 ^@ http://purl.uniprot.org/uniprot/E3IU81 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/298654:FRAEUI1C_RS11540 ^@ http://purl.uniprot.org/uniprot/E3J074 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/298654:FRAEUI1C_RS34565 ^@ http://purl.uniprot.org/uniprot/E3IW07 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS31160 ^@ http://purl.uniprot.org/uniprot/E3J4I7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/298654:FRAEUI1C_RS20940 ^@ http://purl.uniprot.org/uniprot/E3JAM7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/298654:FRAEUI1C_RS19695 ^@ http://purl.uniprot.org/uniprot/E3J6P9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS05305 ^@ http://purl.uniprot.org/uniprot/E3IZZ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/298654:FRAEUI1C_RS25730 ^@ http://purl.uniprot.org/uniprot/E3J6V1 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS21380 ^@ http://purl.uniprot.org/uniprot/E3JBZ7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20505 ^@ http://purl.uniprot.org/uniprot/E3J9B4 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS32925 ^@ http://purl.uniprot.org/uniprot/E3J9U5 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/298654:FRAEUI1C_RS34200 ^@ http://purl.uniprot.org/uniprot/E3IUP4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS04995 ^@ http://purl.uniprot.org/uniprot/E3IYT0 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the IcmF family.|||Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.|||Heterodimer of an alpha and a beta chain.|||Homodimer.|||Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS27780 ^@ http://purl.uniprot.org/uniprot/E3JDE2 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS26935 ^@ http://purl.uniprot.org/uniprot/E3JAR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10780 ^@ http://purl.uniprot.org/uniprot/E3IXP6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04685 ^@ http://purl.uniprot.org/uniprot/E3IXJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05095 ^@ http://purl.uniprot.org/uniprot/E3IYV1 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/298654:FRAEUI1C_RS14685 ^@ http://purl.uniprot.org/uniprot/E3JAC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25585 ^@ http://purl.uniprot.org/uniprot/E3J5Q7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS10960 ^@ http://purl.uniprot.org/uniprot/E3IXT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS29645 ^@ http://purl.uniprot.org/uniprot/E3IZN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08780 ^@ http://purl.uniprot.org/uniprot/E3JBF0 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/298654:FRAEUI1C_RS35750 ^@ http://purl.uniprot.org/uniprot/E3IZX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/298654:FRAEUI1C_RS28270 ^@ http://purl.uniprot.org/uniprot/E3IUI7 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/298654:FRAEUI1C_RS19625 ^@ http://purl.uniprot.org/uniprot/E3J6N6 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS03505 ^@ http://purl.uniprot.org/uniprot/E3ITM2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS04770 ^@ http://purl.uniprot.org/uniprot/E3IXK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07275 ^@ http://purl.uniprot.org/uniprot/E3J697 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22515 ^@ http://purl.uniprot.org/uniprot/E3IVM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS34170 ^@ http://purl.uniprot.org/uniprot/E3IUN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30915 ^@ http://purl.uniprot.org/uniprot/E3J3A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/298654:FRAEUI1C_RS24905 ^@ http://purl.uniprot.org/uniprot/E3J357 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31400 ^@ http://purl.uniprot.org/uniprot/E3J4N5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/298654:FRAEUI1C_RS03465 ^@ http://purl.uniprot.org/uniprot/E3ITL3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS23780 ^@ http://purl.uniprot.org/uniprot/E3J0L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01135 ^@ http://purl.uniprot.org/uniprot/E3J622 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/298654:FRAEUI1C_RS31050 ^@ http://purl.uniprot.org/uniprot/E3J3D2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/298654:FRAEUI1C_RS24320 ^@ http://purl.uniprot.org/uniprot/E3J1T3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/298654:FRAEUI1C_RS20780 ^@ http://purl.uniprot.org/uniprot/E3JAJ5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08895 ^@ http://purl.uniprot.org/uniprot/E3JBH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/298654:FRAEUI1C_RS34135 ^@ http://purl.uniprot.org/uniprot/E3IUN1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS23320 ^@ http://purl.uniprot.org/uniprot/E3IY96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16530 ^@ http://purl.uniprot.org/uniprot/E3IWK7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30970 ^@ http://purl.uniprot.org/uniprot/E3J3B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/298654:FRAEUI1C_RS28710 ^@ http://purl.uniprot.org/uniprot/E3IVV9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS01670 ^@ http://purl.uniprot.org/uniprot/E3J7E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03030 ^@ http://purl.uniprot.org/uniprot/E3JCJ2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14750 ^@ http://purl.uniprot.org/uniprot/E3JAD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08220 ^@ http://purl.uniprot.org/uniprot/E3J8Y3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS36760 ^@ http://purl.uniprot.org/uniprot/E3IX10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05385 ^@ http://purl.uniprot.org/uniprot/E3J009 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26700 ^@ http://purl.uniprot.org/uniprot/E3J9J7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08055 ^@ http://purl.uniprot.org/uniprot/E3J8V2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/298654:FRAEUI1C_RS33615 ^@ http://purl.uniprot.org/uniprot/E3JCF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01525 ^@ http://purl.uniprot.org/uniprot/E3J7B7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/298654:FRAEUI1C_RS11605 ^@ http://purl.uniprot.org/uniprot/E3J086 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS23985 ^@ http://purl.uniprot.org/uniprot/E3J0Q4 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/298654:FRAEUI1C_RS30620 ^@ http://purl.uniprot.org/uniprot/E3J240 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS15015 ^@ http://purl.uniprot.org/uniprot/E3JBM0 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23275 ^@ http://purl.uniprot.org/uniprot/E3IY87 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS25800 ^@ http://purl.uniprot.org/uniprot/E3J6W3 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29755 ^@ http://purl.uniprot.org/uniprot/E3IZQ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS20705 ^@ http://purl.uniprot.org/uniprot/E3JAI0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS14195 ^@ http://purl.uniprot.org/uniprot/E3J902 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS05295 ^@ http://purl.uniprot.org/uniprot/E3IZZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS05455 ^@ http://purl.uniprot.org/uniprot/E3J023 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/298654:FRAEUI1C_RS32315 ^@ http://purl.uniprot.org/uniprot/E3J8E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle GvpF/GvpL family.|||Gas vesicle|||Vesicle http://togogenome.org/gene/298654:FRAEUI1C_RS03170 ^@ http://purl.uniprot.org/uniprot/E3JCL9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/298654:FRAEUI1C_RS06860 ^@ http://purl.uniprot.org/uniprot/E3J4Z1 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21335 ^@ http://purl.uniprot.org/uniprot/E3JBY8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33765 ^@ http://purl.uniprot.org/uniprot/E3JDK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35085 ^@ http://purl.uniprot.org/uniprot/E3IXD6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26720 ^@ http://purl.uniprot.org/uniprot/E3J9K1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14365 ^@ http://purl.uniprot.org/uniprot/E3J936 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34930 ^@ http://purl.uniprot.org/uniprot/E3IXA5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS05610 ^@ http://purl.uniprot.org/uniprot/E3J056 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/298654:FRAEUI1C_RS03940 ^@ http://purl.uniprot.org/uniprot/E3IUY3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28105 ^@ http://purl.uniprot.org/uniprot/E3IUF5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12335 ^@ http://purl.uniprot.org/uniprot/E3J2J7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS21900 ^@ http://purl.uniprot.org/uniprot/E3IU71 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS41660 ^@ http://purl.uniprot.org/uniprot/E3ITY9 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14655 ^@ http://purl.uniprot.org/uniprot/E3JAB8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/298654:FRAEUI1C_RS23800 ^@ http://purl.uniprot.org/uniprot/E3J0L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/298654:FRAEUI1C_RS30365 ^@ http://purl.uniprot.org/uniprot/E3J1Y9 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/298654:FRAEUI1C_RS17965 ^@ http://purl.uniprot.org/uniprot/E3J0J8 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23910 ^@ http://purl.uniprot.org/uniprot/E3J0P0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS01025 ^@ http://purl.uniprot.org/uniprot/E3J4X1 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS30830 ^@ http://purl.uniprot.org/uniprot/E3J391 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/298654:FRAEUI1C_RS35715 ^@ http://purl.uniprot.org/uniprot/E3IZX0 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/298654:FRAEUI1C_RS39805 ^@ http://purl.uniprot.org/uniprot/E3IUF0 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS22865 ^@ http://purl.uniprot.org/uniprot/E3IWY1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22395 ^@ http://purl.uniprot.org/uniprot/E3IVJ9 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS11015 ^@ http://purl.uniprot.org/uniprot/E3IXU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS27015 ^@ http://purl.uniprot.org/uniprot/E3JAT5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS33445 ^@ http://purl.uniprot.org/uniprot/E3JCB4 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS33845 ^@ http://purl.uniprot.org/uniprot/E3JDM0 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23175 ^@ http://purl.uniprot.org/uniprot/E3IY68 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19835 ^@ http://purl.uniprot.org/uniprot/E3J6S5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/298654:FRAEUI1C_RS31640 ^@ http://purl.uniprot.org/uniprot/E3J5W4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14015 ^@ http://purl.uniprot.org/uniprot/E3J7U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS32285 ^@ http://purl.uniprot.org/uniprot/E3J8E1 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/298654:FRAEUI1C_RS10180 ^@ http://purl.uniprot.org/uniprot/E3IV73 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS12385 ^@ http://purl.uniprot.org/uniprot/E3J2K7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00260 ^@ http://purl.uniprot.org/uniprot/E3J3D8 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16455 ^@ http://purl.uniprot.org/uniprot/E3IVF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS16345 ^@ http://purl.uniprot.org/uniprot/E3IVD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23560 ^@ http://purl.uniprot.org/uniprot/E3IZG9 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/298654:FRAEUI1C_RS05255 ^@ http://purl.uniprot.org/uniprot/E3IZY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS22340 ^@ http://purl.uniprot.org/uniprot/E3IVI8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS36110 ^@ http://purl.uniprot.org/uniprot/E3IWJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07080 ^@ http://purl.uniprot.org/uniprot/E3J536 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05130 ^@ http://purl.uniprot.org/uniprot/E3IYV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS33620 ^@ http://purl.uniprot.org/uniprot/E3JCF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05100 ^@ http://purl.uniprot.org/uniprot/E3IYV2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS01915 ^@ http://purl.uniprot.org/uniprot/E3J8M4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS24450 ^@ http://purl.uniprot.org/uniprot/E3J1V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/298654:FRAEUI1C_RS20860 ^@ http://purl.uniprot.org/uniprot/E3JAL1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04680 ^@ http://purl.uniprot.org/uniprot/E3IXJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS22420 ^@ http://purl.uniprot.org/uniprot/E3IVK7 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS19825 ^@ http://purl.uniprot.org/uniprot/E3J6S4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00500 ^@ http://purl.uniprot.org/uniprot/E3J3I5 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/298654:FRAEUI1C_RS00945 ^@ http://purl.uniprot.org/uniprot/E3J4V5 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26585 ^@ http://purl.uniprot.org/uniprot/E3J9H4 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27695 ^@ http://purl.uniprot.org/uniprot/E3JDC6 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/298654:FRAEUI1C_RS15900 ^@ http://purl.uniprot.org/uniprot/E3IU16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05915 ^@ http://purl.uniprot.org/uniprot/E3J176 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30850 ^@ http://purl.uniprot.org/uniprot/E3J395 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS23385 ^@ http://purl.uniprot.org/uniprot/E3IZD7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/298654:FRAEUI1C_RS12045 ^@ http://purl.uniprot.org/uniprot/E3J1D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19110 ^@ http://purl.uniprot.org/uniprot/E3J478 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35305 ^@ http://purl.uniprot.org/uniprot/E3IYK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30510 ^@ http://purl.uniprot.org/uniprot/E3J218 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS35530 ^@ http://purl.uniprot.org/uniprot/E3IZT3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS26895 ^@ http://purl.uniprot.org/uniprot/E3JAR1 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/298654:FRAEUI1C_RS27555 ^@ http://purl.uniprot.org/uniprot/E3JC75 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/298654:FRAEUI1C_RS30295 ^@ http://purl.uniprot.org/uniprot/E3J1X5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS14225 ^@ http://purl.uniprot.org/uniprot/E3J908 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02935 ^@ http://purl.uniprot.org/uniprot/E3JCH1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 53 family. http://togogenome.org/gene/298654:FRAEUI1C_RS18810 ^@ http://purl.uniprot.org/uniprot/E3J417 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/298654:FRAEUI1C_RS04700 ^@ http://purl.uniprot.org/uniprot/E3IXJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/298654:FRAEUI1C_RS30035 ^@ http://purl.uniprot.org/uniprot/E3J0W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/298654:FRAEUI1C_RS05740 ^@ http://purl.uniprot.org/uniprot/E3J141 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/298654:FRAEUI1C_RS19745 ^@ http://purl.uniprot.org/uniprot/E3J6Q9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21585 ^@ http://purl.uniprot.org/uniprot/E3JD65 ^@ Function|||Similarity|||Subunit ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family.|||Homotrimer. http://togogenome.org/gene/298654:FRAEUI1C_RS26790 ^@ http://purl.uniprot.org/uniprot/E3J9L4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18970 ^@ http://purl.uniprot.org/uniprot/E3J450 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/298654:FRAEUI1C_RS15665 ^@ http://purl.uniprot.org/uniprot/E3JD30 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/298654:FRAEUI1C_RS02770 ^@ http://purl.uniprot.org/uniprot/E3JBA6 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29445 ^@ http://purl.uniprot.org/uniprot/E3IYG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21705 ^@ http://purl.uniprot.org/uniprot/E3JD89 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS18125 ^@ http://purl.uniprot.org/uniprot/E3J1J1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25440 ^@ http://purl.uniprot.org/uniprot/E3J5M8 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS10905 ^@ http://purl.uniprot.org/uniprot/E3IXS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05730 ^@ http://purl.uniprot.org/uniprot/E3J139 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS33285 ^@ http://purl.uniprot.org/uniprot/E3JB50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS02645 ^@ http://purl.uniprot.org/uniprot/E3JB83 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/298654:FRAEUI1C_RS25320 ^@ http://purl.uniprot.org/uniprot/E3J5K4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22535 ^@ http://purl.uniprot.org/uniprot/E3IVN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16335 ^@ http://purl.uniprot.org/uniprot/E3IVD4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/298654:FRAEUI1C_RS34920 ^@ http://purl.uniprot.org/uniprot/E3IXA3 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS11620 ^@ http://purl.uniprot.org/uniprot/E3J089 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/298654:FRAEUI1C_RS28605 ^@ http://purl.uniprot.org/uniprot/E3IVT7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS32870 ^@ http://purl.uniprot.org/uniprot/E3J9T3 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12865 ^@ http://purl.uniprot.org/uniprot/E3J3Y2 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29900 ^@ http://purl.uniprot.org/uniprot/E3J0T8 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02395 ^@ http://purl.uniprot.org/uniprot/E3JA01 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/298654:FRAEUI1C_RS25405 ^@ http://purl.uniprot.org/uniprot/E3J5M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03915 ^@ http://purl.uniprot.org/uniprot/E3IUX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS20720 ^@ http://purl.uniprot.org/uniprot/E3JAI3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25105 ^@ http://purl.uniprot.org/uniprot/E3J4C9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10035 ^@ http://purl.uniprot.org/uniprot/E3IV44 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31710 ^@ http://purl.uniprot.org/uniprot/E3J5X8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/298654:FRAEUI1C_RS25970 ^@ http://purl.uniprot.org/uniprot/E3J6Z6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01470 ^@ http://purl.uniprot.org/uniprot/E3J7A6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/298654:FRAEUI1C_RS31055 ^@ http://purl.uniprot.org/uniprot/E3J3D3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS33880 ^@ http://purl.uniprot.org/uniprot/E3JDM7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS31375 ^@ http://purl.uniprot.org/uniprot/E3J4N0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05810 ^@ http://purl.uniprot.org/uniprot/E3J155 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS33020 ^@ http://purl.uniprot.org/uniprot/E3JAZ5 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/298654:FRAEUI1C_RS17040 ^@ http://purl.uniprot.org/uniprot/E3IXY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01105 ^@ http://purl.uniprot.org/uniprot/E3J615 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/298654:FRAEUI1C_RS11185 ^@ http://purl.uniprot.org/uniprot/E3IZ04 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09790 ^@ http://purl.uniprot.org/uniprot/E3ITW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/298654:FRAEUI1C_RS36015 ^@ http://purl.uniprot.org/uniprot/E3JA27 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS34445 ^@ http://purl.uniprot.org/uniprot/E3IVY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14875 ^@ http://purl.uniprot.org/uniprot/E3JAG2 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS17525 ^@ http://purl.uniprot.org/uniprot/E3IZA8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/298654:FRAEUI1C_RS21180 ^@ http://purl.uniprot.org/uniprot/E3JBV7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25595 ^@ http://purl.uniprot.org/uniprot/E3J5Q9 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12190 ^@ http://purl.uniprot.org/uniprot/E3J1G1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS25425 ^@ http://purl.uniprot.org/uniprot/E3J5M5 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/298654:FRAEUI1C_RS00905 ^@ http://purl.uniprot.org/uniprot/E3J4U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25450 ^@ http://purl.uniprot.org/uniprot/E3J5N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00850 ^@ http://purl.uniprot.org/uniprot/E3J4T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08245 ^@ http://purl.uniprot.org/uniprot/E3J8Y8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS02840 ^@ http://purl.uniprot.org/uniprot/E3JBB8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS20845 ^@ http://purl.uniprot.org/uniprot/E3JAK8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04800 ^@ http://purl.uniprot.org/uniprot/E3IXL5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS36130 ^@ http://purl.uniprot.org/uniprot/E3IXR7 ^@ Similarity ^@ Belongs to the SurE nucleotidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10175 ^@ http://purl.uniprot.org/uniprot/E3IV72 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS30290 ^@ http://purl.uniprot.org/uniprot/E3J1X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07590 ^@ http://purl.uniprot.org/uniprot/E3J7I0 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32770 ^@ http://purl.uniprot.org/uniprot/E3J9R5 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS19195 ^@ http://purl.uniprot.org/uniprot/E3J5D1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS29435 ^@ http://purl.uniprot.org/uniprot/E3IYG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13215 ^@ http://purl.uniprot.org/uniprot/E3J587 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10530 ^@ http://purl.uniprot.org/uniprot/E3IWH6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/298654:FRAEUI1C_RS25610 ^@ http://purl.uniprot.org/uniprot/E3J5R2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/298654:FRAEUI1C_RS01150 ^@ http://purl.uniprot.org/uniprot/E3J625 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08200 ^@ http://purl.uniprot.org/uniprot/E3J8X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS32815 ^@ http://purl.uniprot.org/uniprot/E3J9S4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31035 ^@ http://purl.uniprot.org/uniprot/E3J3D1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/298654:FRAEUI1C_RS20540 ^@ http://purl.uniprot.org/uniprot/E3J9C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09820 ^@ http://purl.uniprot.org/uniprot/E3ITX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00785 ^@ http://purl.uniprot.org/uniprot/E3J4S3 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS11890 ^@ http://purl.uniprot.org/uniprot/E3J1A5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS20150 ^@ http://purl.uniprot.org/uniprot/E3J814 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31425 ^@ http://purl.uniprot.org/uniprot/E3J4N8 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25085 ^@ http://purl.uniprot.org/uniprot/E3J4C5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02920 ^@ http://purl.uniprot.org/uniprot/E3JCG8 ^@ Similarity ^@ Belongs to the gamma-BBH/TMLD family. http://togogenome.org/gene/298654:FRAEUI1C_RS20825 ^@ http://purl.uniprot.org/uniprot/E3JAK4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30930 ^@ http://purl.uniprot.org/uniprot/E3J3B1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/298654:FRAEUI1C_RS03210 ^@ http://purl.uniprot.org/uniprot/E3JCM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/298654:FRAEUI1C_RS24085 ^@ http://purl.uniprot.org/uniprot/E3J0S5 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/298654:FRAEUI1C_RS33015 ^@ http://purl.uniprot.org/uniprot/E3JAZ4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/298654:FRAEUI1C_RS31250 ^@ http://purl.uniprot.org/uniprot/E3J4K5 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/298654:FRAEUI1C_RS24690 ^@ http://purl.uniprot.org/uniprot/E3J313 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/298654:FRAEUI1C_RS03130 ^@ http://purl.uniprot.org/uniprot/E3JCL1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS31170 ^@ http://purl.uniprot.org/uniprot/E3J4I9 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/298654:FRAEUI1C_RS04940 ^@ http://purl.uniprot.org/uniprot/E3IYS2 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/298654:FRAEUI1C_RS31155 ^@ http://purl.uniprot.org/uniprot/E3J4I6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS27030 ^@ http://purl.uniprot.org/uniprot/E3JAT8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26730 ^@ http://purl.uniprot.org/uniprot/E3J9K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33070 ^@ http://purl.uniprot.org/uniprot/E3JB06 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11240 ^@ http://purl.uniprot.org/uniprot/E3IZ16 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS04645 ^@ http://purl.uniprot.org/uniprot/E3IXI4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/298654:FRAEUI1C_RS09740 ^@ http://purl.uniprot.org/uniprot/E3ITV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/298654:FRAEUI1C_RS05135 ^@ http://purl.uniprot.org/uniprot/E3IYV9 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15185 ^@ http://purl.uniprot.org/uniprot/E3JBQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/298654:FRAEUI1C_RS06570 ^@ http://purl.uniprot.org/uniprot/E3J3P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04020 ^@ http://purl.uniprot.org/uniprot/E3IUZ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS11155 ^@ http://purl.uniprot.org/uniprot/E3IYZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11360 ^@ http://purl.uniprot.org/uniprot/E3IZ40 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04735 ^@ http://purl.uniprot.org/uniprot/E3IXK2 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/298654:FRAEUI1C_RS06265 ^@ http://purl.uniprot.org/uniprot/E3J2F2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22365 ^@ http://purl.uniprot.org/uniprot/E3IVJ3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22825 ^@ http://purl.uniprot.org/uniprot/E3IWX3 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/298654:FRAEUI1C_RS17235 ^@ http://purl.uniprot.org/uniprot/E3IY22 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35540 ^@ http://purl.uniprot.org/uniprot/E3IZT5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS16905 ^@ http://purl.uniprot.org/uniprot/E3IXV6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS02350 ^@ http://purl.uniprot.org/uniprot/E3J9Z2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17715 ^@ http://purl.uniprot.org/uniprot/E3J0E8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/298654:FRAEUI1C_RS31385 ^@ http://purl.uniprot.org/uniprot/E3J4N2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/298654:FRAEUI1C_RS04830 ^@ http://purl.uniprot.org/uniprot/E3IXM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS20445 ^@ http://purl.uniprot.org/uniprot/E3J9A2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31365 ^@ http://purl.uniprot.org/uniprot/E3J4M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS20020 ^@ http://purl.uniprot.org/uniprot/E3J7Y9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/298654:FRAEUI1C_RS32325 ^@ http://purl.uniprot.org/uniprot/E3J8E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle GvpK family.|||Gas vesicle|||Vesicle http://togogenome.org/gene/298654:FRAEUI1C_RS03790 ^@ http://purl.uniprot.org/uniprot/E3IUV4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS00535 ^@ http://purl.uniprot.org/uniprot/E3J3J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18555 ^@ http://purl.uniprot.org/uniprot/E3J2T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01595 ^@ http://purl.uniprot.org/uniprot/E3J7D0 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS27145 ^@ http://purl.uniprot.org/uniprot/E3JAW1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31310 ^@ http://purl.uniprot.org/uniprot/E3J4L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13210 ^@ http://purl.uniprot.org/uniprot/E3J586 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30960 ^@ http://purl.uniprot.org/uniprot/E3J3B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS29580 ^@ http://purl.uniprot.org/uniprot/E3IZM0 ^@ Similarity ^@ Belongs to the phosphosulfolactate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03105 ^@ http://purl.uniprot.org/uniprot/E3JCK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS04615 ^@ http://purl.uniprot.org/uniprot/E3IXH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/298654:FRAEUI1C_RS34775 ^@ http://purl.uniprot.org/uniprot/E3IW47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS22860 ^@ http://purl.uniprot.org/uniprot/E3IWY0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/298654:FRAEUI1C_RS21395 ^@ http://purl.uniprot.org/uniprot/E3JC00 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20725 ^@ http://purl.uniprot.org/uniprot/E3JAI4 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS23490 ^@ http://purl.uniprot.org/uniprot/E3IZF6 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS01430 ^@ http://purl.uniprot.org/uniprot/E3J798 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01465 ^@ http://purl.uniprot.org/uniprot/E3J7A5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/298654:FRAEUI1C_RS25160 ^@ http://purl.uniprot.org/uniprot/E3J4E0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS32890 ^@ http://purl.uniprot.org/uniprot/E3J9T7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05710 ^@ http://purl.uniprot.org/uniprot/E3J135 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/298654:FRAEUI1C_RS02460 ^@ http://purl.uniprot.org/uniprot/E3JA14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23125 ^@ http://purl.uniprot.org/uniprot/E3IY58 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS04640 ^@ http://purl.uniprot.org/uniprot/E3IXI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS34730 ^@ http://purl.uniprot.org/uniprot/E3IW38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30380 ^@ http://purl.uniprot.org/uniprot/E3J1Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09545 ^@ http://purl.uniprot.org/uniprot/E3ITS3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS24505 ^@ http://purl.uniprot.org/uniprot/E3J1W9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25100 ^@ http://purl.uniprot.org/uniprot/E3J4C8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08455 ^@ http://purl.uniprot.org/uniprot/E3JA62 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS22285 ^@ http://purl.uniprot.org/uniprot/E3IVH7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS10065 ^@ http://purl.uniprot.org/uniprot/E3IV50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15300 ^@ http://purl.uniprot.org/uniprot/E3JBS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23465 ^@ http://purl.uniprot.org/uniprot/E3IZF1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/298654:FRAEUI1C_RS23250 ^@ http://purl.uniprot.org/uniprot/E3IY82 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS34725 ^@ http://purl.uniprot.org/uniprot/E3IW37 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS02375 ^@ http://purl.uniprot.org/uniprot/E3J9Z7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31800 ^@ http://purl.uniprot.org/uniprot/E3J5Z7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS18045 ^@ http://purl.uniprot.org/uniprot/E3J1H5 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30985 ^@ http://purl.uniprot.org/uniprot/E3J3C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS31465 ^@ http://purl.uniprot.org/uniprot/E3J5S9 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/298654:FRAEUI1C_RS08365 ^@ http://purl.uniprot.org/uniprot/E3JA43 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/298654:FRAEUI1C_RS11865 ^@ http://purl.uniprot.org/uniprot/E3J199 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS22135 ^@ http://purl.uniprot.org/uniprot/E3IUB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07910 ^@ http://purl.uniprot.org/uniprot/E3J8S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14470 ^@ http://purl.uniprot.org/uniprot/E3J955 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00615 ^@ http://purl.uniprot.org/uniprot/E3J3K7 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS11415 ^@ http://purl.uniprot.org/uniprot/E3IZ51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23825 ^@ http://purl.uniprot.org/uniprot/E3J0M3 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15350 ^@ http://purl.uniprot.org/uniprot/E3JCW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24560 ^@ http://purl.uniprot.org/uniprot/E3J2Y7 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/298654:FRAEUI1C_RS29770 ^@ http://purl.uniprot.org/uniprot/E3IZQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06175 ^@ http://purl.uniprot.org/uniprot/E3J2D4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04695 ^@ http://purl.uniprot.org/uniprot/E3IXJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS24110 ^@ http://purl.uniprot.org/uniprot/E3J0T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03555 ^@ http://purl.uniprot.org/uniprot/E3ITN2 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS19450 ^@ http://purl.uniprot.org/uniprot/E3J5I1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. http://togogenome.org/gene/298654:FRAEUI1C_RS34470 ^@ http://purl.uniprot.org/uniprot/E3IVY8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS13150 ^@ http://purl.uniprot.org/uniprot/E3J574 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS18110 ^@ http://purl.uniprot.org/uniprot/E3J1I8 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/298654:FRAEUI1C_RS26430 ^@ http://purl.uniprot.org/uniprot/E3J8B4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16505 ^@ http://purl.uniprot.org/uniprot/E3IWK2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06490 ^@ http://purl.uniprot.org/uniprot/E3J3N0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS41295 ^@ http://purl.uniprot.org/uniprot/E3J6Y1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS30820 ^@ http://purl.uniprot.org/uniprot/E3J389 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/298654:FRAEUI1C_RS01005 ^@ http://purl.uniprot.org/uniprot/E3J4W7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/298654:FRAEUI1C_RS03085 ^@ http://purl.uniprot.org/uniprot/E3JCK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS17875 ^@ http://purl.uniprot.org/uniprot/E3J0I0 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS35135 ^@ http://purl.uniprot.org/uniprot/E3IXE6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/298654:FRAEUI1C_RS29740 ^@ http://purl.uniprot.org/uniprot/E3IZQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28540 ^@ http://purl.uniprot.org/uniprot/E3IVS4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22660 ^@ http://purl.uniprot.org/uniprot/E3IWT8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08990 ^@ http://purl.uniprot.org/uniprot/E3JBJ2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS04820 ^@ http://purl.uniprot.org/uniprot/E3IXL9 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/298654:FRAEUI1C_RS01550 ^@ http://purl.uniprot.org/uniprot/E3J7C2 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/298654:FRAEUI1C_RS06385 ^@ http://purl.uniprot.org/uniprot/E3J3L1 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04625 ^@ http://purl.uniprot.org/uniprot/E3IXI0 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/298654:FRAEUI1C_RS05930 ^@ http://purl.uniprot.org/uniprot/E3J179 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/298654:FRAEUI1C_RS02040 ^@ http://purl.uniprot.org/uniprot/E3J8P9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS30780 ^@ http://purl.uniprot.org/uniprot/E3J381 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14410 ^@ http://purl.uniprot.org/uniprot/E3J944 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10925 ^@ http://purl.uniprot.org/uniprot/E3IXS5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/298654:FRAEUI1C_RS00010 ^@ http://purl.uniprot.org/uniprot/E3J251 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/298654:FRAEUI1C_RS04660 ^@ http://purl.uniprot.org/uniprot/E3IXI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31240 ^@ http://purl.uniprot.org/uniprot/E3J4K3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS26675 ^@ http://purl.uniprot.org/uniprot/E3J9J2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20500 ^@ http://purl.uniprot.org/uniprot/E3J9B3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS31185 ^@ http://purl.uniprot.org/uniprot/E3J4J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS15680 ^@ http://purl.uniprot.org/uniprot/E3JD33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15025 ^@ http://purl.uniprot.org/uniprot/E3JBM2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27545 ^@ http://purl.uniprot.org/uniprot/E3JC73 ^@ Caution|||Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS20190 ^@ http://purl.uniprot.org/uniprot/E3J822 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18120 ^@ http://purl.uniprot.org/uniprot/E3J1J0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/298654:FRAEUI1C_RS09275 ^@ http://purl.uniprot.org/uniprot/E3JCS7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS24070 ^@ http://purl.uniprot.org/uniprot/E3J0S2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/298654:FRAEUI1C_RS21965 ^@ http://purl.uniprot.org/uniprot/E3IU84 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23820 ^@ http://purl.uniprot.org/uniprot/E3J0M2 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/298654:FRAEUI1C_RS09805 ^@ http://purl.uniprot.org/uniprot/E3ITX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS00185 ^@ http://purl.uniprot.org/uniprot/E3J285 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10135 ^@ http://purl.uniprot.org/uniprot/E3IV64 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS00965 ^@ http://purl.uniprot.org/uniprot/E3J4V9 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08835 ^@ http://purl.uniprot.org/uniprot/E3JBG1 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26495 ^@ http://purl.uniprot.org/uniprot/E3J9F6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26810 ^@ http://purl.uniprot.org/uniprot/E3J9L8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11760 ^@ http://purl.uniprot.org/uniprot/E3J0B6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/298654:FRAEUI1C_RS12845 ^@ http://purl.uniprot.org/uniprot/E3J3X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12735 ^@ http://purl.uniprot.org/uniprot/E3J3V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14095 ^@ http://purl.uniprot.org/uniprot/E3J7V7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19025 ^@ http://purl.uniprot.org/uniprot/E3J461 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS35700 ^@ http://purl.uniprot.org/uniprot/E3IZW6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS09610 ^@ http://purl.uniprot.org/uniprot/E3ITT5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS25060 ^@ http://purl.uniprot.org/uniprot/E3J4C0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15850 ^@ http://purl.uniprot.org/uniprot/E3IU06 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS25275 ^@ http://purl.uniprot.org/uniprot/E3J4G3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/298654:FRAEUI1C_RS31615 ^@ http://purl.uniprot.org/uniprot/E3J5V9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS13345 ^@ http://purl.uniprot.org/uniprot/E3J5B2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22705 ^@ http://purl.uniprot.org/uniprot/E3IWU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS02555 ^@ http://purl.uniprot.org/uniprot/E3JB65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/298654:FRAEUI1C_RS02600 ^@ http://purl.uniprot.org/uniprot/E3JB74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10890 ^@ http://purl.uniprot.org/uniprot/E3IXR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28435 ^@ http://purl.uniprot.org/uniprot/E3IVQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30965 ^@ http://purl.uniprot.org/uniprot/E3J3B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/298654:FRAEUI1C_RS15910 ^@ http://purl.uniprot.org/uniprot/E3IU18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05355 ^@ http://purl.uniprot.org/uniprot/E3J003 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/298654:FRAEUI1C_RS11845 ^@ http://purl.uniprot.org/uniprot/E3J195 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22915 ^@ http://purl.uniprot.org/uniprot/E3IWZ1 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/298654:FRAEUI1C_RS00035 ^@ http://purl.uniprot.org/uniprot/E3J256 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/298654:FRAEUI1C_RS13455 ^@ http://purl.uniprot.org/uniprot/E3J6F4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/298654:FRAEUI1C_RS17895 ^@ http://purl.uniprot.org/uniprot/E3J0I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29240 ^@ http://purl.uniprot.org/uniprot/E3IYC5 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28410 ^@ http://purl.uniprot.org/uniprot/E3IVP8 ^@ Similarity ^@ Belongs to the ERG4/ERG24 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12135 ^@ http://purl.uniprot.org/uniprot/E3J1F1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27760 ^@ http://purl.uniprot.org/uniprot/E3JDD8 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/298654:FRAEUI1C_RS25330 ^@ http://purl.uniprot.org/uniprot/E3J5K6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03900 ^@ http://purl.uniprot.org/uniprot/E3IUX6 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/298654:FRAEUI1C_RS29725 ^@ http://purl.uniprot.org/uniprot/E3IZP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26410 ^@ http://purl.uniprot.org/uniprot/E3J8B0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12360 ^@ http://purl.uniprot.org/uniprot/E3J2K2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS09870 ^@ http://purl.uniprot.org/uniprot/E3IV12 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24655 ^@ http://purl.uniprot.org/uniprot/E3J306 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10605 ^@ http://purl.uniprot.org/uniprot/E3IWJ0 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00700 ^@ http://purl.uniprot.org/uniprot/E3J4Q6 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/298654:FRAEUI1C_RS18990 ^@ http://purl.uniprot.org/uniprot/E3J454 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21125 ^@ http://purl.uniprot.org/uniprot/E3JBU6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14050 ^@ http://purl.uniprot.org/uniprot/E3J7U8 ^@ Caution|||Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS22000 ^@ http://purl.uniprot.org/uniprot/E3IU91 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS12965 ^@ http://purl.uniprot.org/uniprot/E3J402 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26925 ^@ http://purl.uniprot.org/uniprot/E3JAR7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12640 ^@ http://purl.uniprot.org/uniprot/E3J3T8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18665 ^@ http://purl.uniprot.org/uniprot/E3J2V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16210 ^@ http://purl.uniprot.org/uniprot/E3IVA8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08675 ^@ http://purl.uniprot.org/uniprot/E3JBD1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19740 ^@ http://purl.uniprot.org/uniprot/E3J6Q8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS13520 ^@ http://purl.uniprot.org/uniprot/E3J6G8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/298654:FRAEUI1C_RS30910 ^@ http://purl.uniprot.org/uniprot/E3J3A7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS08280 ^@ http://purl.uniprot.org/uniprot/E3JA26 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS31655 ^@ http://purl.uniprot.org/uniprot/E3J5W7 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/298654:FRAEUI1C_RS30870 ^@ http://purl.uniprot.org/uniprot/E3J399 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/298654:FRAEUI1C_RS30770 ^@ http://purl.uniprot.org/uniprot/E3J379 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS04085 ^@ http://purl.uniprot.org/uniprot/E3IV11 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03100 ^@ http://purl.uniprot.org/uniprot/E3JCK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/298654:FRAEUI1C_RS07895 ^@ http://purl.uniprot.org/uniprot/E3J8R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14755 ^@ http://purl.uniprot.org/uniprot/E3JAD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14110 ^@ http://purl.uniprot.org/uniprot/E3J7W0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04225 ^@ http://purl.uniprot.org/uniprot/E3IW78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/298654:FRAEUI1C_RS24340 ^@ http://purl.uniprot.org/uniprot/E3J1T7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16230 ^@ http://purl.uniprot.org/uniprot/E3IVB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30075 ^@ http://purl.uniprot.org/uniprot/E3J0X3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS34925 ^@ http://purl.uniprot.org/uniprot/E3IXA4 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS16435 ^@ http://purl.uniprot.org/uniprot/E3IVF4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30615 ^@ http://purl.uniprot.org/uniprot/E3J239 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS33195 ^@ http://purl.uniprot.org/uniprot/E3JB32 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS34490 ^@ http://purl.uniprot.org/uniprot/E3IVZ2 ^@ Similarity ^@ Belongs to the Vsr family. http://togogenome.org/gene/298654:FRAEUI1C_RS37100 ^@ http://purl.uniprot.org/uniprot/E3J8K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35745 ^@ http://purl.uniprot.org/uniprot/E3IZX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/298654:FRAEUI1C_RS30980 ^@ http://purl.uniprot.org/uniprot/E3J3C1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS06820 ^@ http://purl.uniprot.org/uniprot/E3J4Y3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31300 ^@ http://purl.uniprot.org/uniprot/E3J4L5 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/298654:FRAEUI1C_RS04845 ^@ http://purl.uniprot.org/uniprot/E3IXM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/298654:FRAEUI1C_RS25580 ^@ http://purl.uniprot.org/uniprot/E3J5Q6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29230 ^@ http://purl.uniprot.org/uniprot/E3IYC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/298654:FRAEUI1C_RS33660 ^@ http://purl.uniprot.org/uniprot/E3JCF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18745 ^@ http://purl.uniprot.org/uniprot/E3J2X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS02830 ^@ http://purl.uniprot.org/uniprot/E3JBB6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS10750 ^@ http://purl.uniprot.org/uniprot/E3IXP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03370 ^@ http://purl.uniprot.org/uniprot/E3ITJ8 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/298654:FRAEUI1C_RS28685 ^@ http://purl.uniprot.org/uniprot/E3IVV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS20495 ^@ http://purl.uniprot.org/uniprot/E3J9B2 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14880 ^@ http://purl.uniprot.org/uniprot/E3JAG3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS26760 ^@ http://purl.uniprot.org/uniprot/E3J9K8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03205 ^@ http://purl.uniprot.org/uniprot/E3JCM6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/298654:FRAEUI1C_RS31025 ^@ http://purl.uniprot.org/uniprot/E3J3C9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18225 ^@ http://purl.uniprot.org/uniprot/E3J1L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03335 ^@ http://purl.uniprot.org/uniprot/E3ITJ1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS21325 ^@ http://purl.uniprot.org/uniprot/E3JBY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00345 ^@ http://purl.uniprot.org/uniprot/E3J3F5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30685 ^@ http://purl.uniprot.org/uniprot/E3J361 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30955 ^@ http://purl.uniprot.org/uniprot/E3J3B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS06975 ^@ http://purl.uniprot.org/uniprot/E3J515 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11595 ^@ http://purl.uniprot.org/uniprot/E3J084 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS06365 ^@ http://purl.uniprot.org/uniprot/E3J2H2 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/298654:FRAEUI1C_RS35400 ^@ http://purl.uniprot.org/uniprot/E3IYM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS08655 ^@ http://purl.uniprot.org/uniprot/E3JA97 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS00990 ^@ http://purl.uniprot.org/uniprot/E3J4W4 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/298654:FRAEUI1C_RS10060 ^@ http://purl.uniprot.org/uniprot/E3IV49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13790 ^@ http://purl.uniprot.org/uniprot/E3J7P6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11805 ^@ http://purl.uniprot.org/uniprot/E3J0C5 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS01910 ^@ http://purl.uniprot.org/uniprot/E3J8M3 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/298654:FRAEUI1C_RS03415 ^@ http://purl.uniprot.org/uniprot/E3ITK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/298654:FRAEUI1C_RS09765 ^@ http://purl.uniprot.org/uniprot/E3ITW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/298654:FRAEUI1C_RS08080 ^@ http://purl.uniprot.org/uniprot/E3J8V7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00300 ^@ http://purl.uniprot.org/uniprot/E3J3E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS20885 ^@ http://purl.uniprot.org/uniprot/E3JAL6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14775 ^@ http://purl.uniprot.org/uniprot/E3JAE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS08385 ^@ http://purl.uniprot.org/uniprot/E3JA48 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/298654:FRAEUI1C_RS32060 ^@ http://purl.uniprot.org/uniprot/E3J763 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/298654:FRAEUI1C_RS17680 ^@ http://purl.uniprot.org/uniprot/E3J0E1 ^@ Function|||Similarity ^@ Belongs to the ribose 1,5-bisphosphokinase family.|||Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). http://togogenome.org/gene/298654:FRAEUI1C_RS22335 ^@ http://purl.uniprot.org/uniprot/E3IVI7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS04040 ^@ http://purl.uniprot.org/uniprot/E3IV02 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/298654:FRAEUI1C_RS21695 ^@ http://purl.uniprot.org/uniprot/E3JD87 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS09280 ^@ http://purl.uniprot.org/uniprot/E3JCS8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS29390 ^@ http://purl.uniprot.org/uniprot/E3IYF5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS30445 ^@ http://purl.uniprot.org/uniprot/E3J205 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS35660 ^@ http://purl.uniprot.org/uniprot/E3IZV9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05435 ^@ http://purl.uniprot.org/uniprot/E3J019 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS34830 ^@ http://purl.uniprot.org/uniprot/E3IX87 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/298654:FRAEUI1C_RS31650 ^@ http://purl.uniprot.org/uniprot/E3J5W6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/298654:FRAEUI1C_RS00030 ^@ http://purl.uniprot.org/uniprot/E3J255 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/298654:FRAEUI1C_RS08505 ^@ http://purl.uniprot.org/uniprot/E3JA72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/298654:FRAEUI1C_RS23415 ^@ http://purl.uniprot.org/uniprot/E3IZE3 ^@ Caution|||Similarity ^@ Belongs to the CTP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS26295 ^@ http://purl.uniprot.org/uniprot/E3J887 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01110 ^@ http://purl.uniprot.org/uniprot/E3J616 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/298654:FRAEUI1C_RS12715 ^@ http://purl.uniprot.org/uniprot/E3J3V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03685 ^@ http://purl.uniprot.org/uniprot/E3ITQ7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14185 ^@ http://purl.uniprot.org/uniprot/E3J900 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS30825 ^@ http://purl.uniprot.org/uniprot/E3J390 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12670 ^@ http://purl.uniprot.org/uniprot/E3J3U4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS25270 ^@ http://purl.uniprot.org/uniprot/E3J4G2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27795 ^@ http://purl.uniprot.org/uniprot/E3JDE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS22090 ^@ http://purl.uniprot.org/uniprot/E3IUA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12790 ^@ http://purl.uniprot.org/uniprot/E3J3W8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12810 ^@ http://purl.uniprot.org/uniprot/E3J3X2 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS13605 ^@ http://purl.uniprot.org/uniprot/E3J6I6 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/298654:FRAEUI1C_RS30150 ^@ http://purl.uniprot.org/uniprot/E3J0Y8 ^@ Function|||Similarity ^@ Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.|||In the C-terminal section; belongs to the radical SAM superfamily. CofH family.|||In the N-terminal section; belongs to the radical SAM superfamily. CofG family. http://togogenome.org/gene/298654:FRAEUI1C_RS00225 ^@ http://purl.uniprot.org/uniprot/E3J294 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/298654:FRAEUI1C_RS19210 ^@ http://purl.uniprot.org/uniprot/E3J5D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27150 ^@ http://purl.uniprot.org/uniprot/E3JAW2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS16805 ^@ http://purl.uniprot.org/uniprot/E3IWR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10400 ^@ http://purl.uniprot.org/uniprot/E3IWF4 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00975 ^@ http://purl.uniprot.org/uniprot/E3J4W1 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/298654:FRAEUI1C_RS39680 ^@ http://purl.uniprot.org/uniprot/E3JAM6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS32185 ^@ http://purl.uniprot.org/uniprot/E3J8C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/298654:FRAEUI1C_RS03580 ^@ http://purl.uniprot.org/uniprot/E3ITN7 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/298654:FRAEUI1C_RS20830 ^@ http://purl.uniprot.org/uniprot/E3JAK5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24640 ^@ http://purl.uniprot.org/uniprot/E3J303 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS17315 ^@ http://purl.uniprot.org/uniprot/E3IZ66 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS17960 ^@ http://purl.uniprot.org/uniprot/E3J0J7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS07385 ^@ http://purl.uniprot.org/uniprot/E3J6B7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35275 ^@ http://purl.uniprot.org/uniprot/E3IYK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08595 ^@ http://purl.uniprot.org/uniprot/E3JA85 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS33535 ^@ http://purl.uniprot.org/uniprot/E3JCD3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/298654:FRAEUI1C_RS28620 ^@ http://purl.uniprot.org/uniprot/E3IVU0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30995 ^@ http://purl.uniprot.org/uniprot/E3J3C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/298654:FRAEUI1C_RS18605 ^@ http://purl.uniprot.org/uniprot/E3J2U5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/298654:FRAEUI1C_RS13515 ^@ http://purl.uniprot.org/uniprot/E3J6G7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27975 ^@ http://purl.uniprot.org/uniprot/E3JDI0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/298654:FRAEUI1C_RS05550 ^@ http://purl.uniprot.org/uniprot/E3J044 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/298654:FRAEUI1C_RS04610 ^@ http://purl.uniprot.org/uniprot/E3IXH7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS12475 ^@ http://purl.uniprot.org/uniprot/E3J2M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09490 ^@ http://purl.uniprot.org/uniprot/E3ITR2 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/298654:FRAEUI1C_RS08790 ^@ http://purl.uniprot.org/uniprot/E3JBF2 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00495 ^@ http://purl.uniprot.org/uniprot/E3J3I4 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/298654:FRAEUI1C_RS30335 ^@ http://purl.uniprot.org/uniprot/E3J1Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01015 ^@ http://purl.uniprot.org/uniprot/E3J4W9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/298654:FRAEUI1C_RS24820 ^@ http://purl.uniprot.org/uniprot/E3J340 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS21825 ^@ http://purl.uniprot.org/uniprot/E3JDA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS30860 ^@ http://purl.uniprot.org/uniprot/E3J397 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/298654:FRAEUI1C_RS25505 ^@ http://purl.uniprot.org/uniprot/E3J5P1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS17405 ^@ http://purl.uniprot.org/uniprot/E3IZ84 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16145 ^@ http://purl.uniprot.org/uniprot/E3IV95 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06150 ^@ http://purl.uniprot.org/uniprot/E3J2C9 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS04260 ^@ http://purl.uniprot.org/uniprot/E3IW85 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS25615 ^@ http://purl.uniprot.org/uniprot/E3J5R3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31095 ^@ http://purl.uniprot.org/uniprot/E3J4H4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26530 ^@ http://purl.uniprot.org/uniprot/E3J9G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LigB/MhpB extradiol dioxygenase family.|||Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.|||Homotetramer. http://togogenome.org/gene/298654:FRAEUI1C_RS41545 ^@ http://purl.uniprot.org/uniprot/E3JB81 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/298654:FRAEUI1C_RS25225 ^@ http://purl.uniprot.org/uniprot/E3J4F3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS09975 ^@ http://purl.uniprot.org/uniprot/E3IV32 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS11465 ^@ http://purl.uniprot.org/uniprot/E3J061 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01615 ^@ http://purl.uniprot.org/uniprot/E3J7D4 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/298654:FRAEUI1C_RS32240 ^@ http://purl.uniprot.org/uniprot/E3J8D3 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/298654:FRAEUI1C_RS21320 ^@ http://purl.uniprot.org/uniprot/E3JBY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS17735 ^@ http://purl.uniprot.org/uniprot/E3J0F2 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32330 ^@ http://purl.uniprot.org/uniprot/E3J8F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the gas vesicle GvpA family.|||Gas vesicle shell|||Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.|||The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle. http://togogenome.org/gene/298654:FRAEUI1C_RS09835 ^@ http://purl.uniprot.org/uniprot/E3ITX8 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10800 ^@ http://purl.uniprot.org/uniprot/E3IXQ0 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS16175 ^@ http://purl.uniprot.org/uniprot/E3IVA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29420 ^@ http://purl.uniprot.org/uniprot/E3IYG1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS24775 ^@ http://purl.uniprot.org/uniprot/E3J330 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS05390 ^@ http://purl.uniprot.org/uniprot/E3J010 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/298654:FRAEUI1C_RS26370 ^@ http://purl.uniprot.org/uniprot/E3J8A2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03095 ^@ http://purl.uniprot.org/uniprot/E3JCK4 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/298654:FRAEUI1C_RS28545 ^@ http://purl.uniprot.org/uniprot/E3IVS5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33355 ^@ http://purl.uniprot.org/uniprot/E3JC96 ^@ Similarity ^@ Belongs to the Vsr family. http://togogenome.org/gene/298654:FRAEUI1C_RS05785 ^@ http://purl.uniprot.org/uniprot/E3J149 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30835 ^@ http://purl.uniprot.org/uniprot/E3J392 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/298654:FRAEUI1C_RS09115 ^@ http://purl.uniprot.org/uniprot/E3JCP9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS23870 ^@ http://purl.uniprot.org/uniprot/E3J0N2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS05525 ^@ http://purl.uniprot.org/uniprot/E3J039 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/298654:FRAEUI1C_RS21630 ^@ http://purl.uniprot.org/uniprot/E3JD74 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS16090 ^@ http://purl.uniprot.org/uniprot/E3IU55 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26230 ^@ http://purl.uniprot.org/uniprot/E3J874 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35695 ^@ http://purl.uniprot.org/uniprot/E3IZW5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS26105 ^@ http://purl.uniprot.org/uniprot/E3J849 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS14155 ^@ http://purl.uniprot.org/uniprot/E3J7W9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34965 ^@ http://purl.uniprot.org/uniprot/E3IXB1 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/298654:FRAEUI1C_RS02130 ^@ http://purl.uniprot.org/uniprot/E3J8R6 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS34765 ^@ http://purl.uniprot.org/uniprot/E3IW45 ^@ Function ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS08350 ^@ http://purl.uniprot.org/uniprot/E3JA40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/298654:FRAEUI1C_RS29300 ^@ http://purl.uniprot.org/uniprot/E3IYD7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/298654:FRAEUI1C_RS03125 ^@ http://purl.uniprot.org/uniprot/E3JCL0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/298654:FRAEUI1C_RS03350 ^@ http://purl.uniprot.org/uniprot/E3ITJ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS35755 ^@ http://purl.uniprot.org/uniprot/E3IZX9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/298654:FRAEUI1C_RS16255 ^@ http://purl.uniprot.org/uniprot/E3IVB8 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30085 ^@ http://purl.uniprot.org/uniprot/E3J0X5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33170 ^@ http://purl.uniprot.org/uniprot/E3JB27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33145 ^@ http://purl.uniprot.org/uniprot/E3JB21 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15860 ^@ http://purl.uniprot.org/uniprot/E3IU08 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20565 ^@ http://purl.uniprot.org/uniprot/E3J9C6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS23370 ^@ http://purl.uniprot.org/uniprot/E3IZD4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24665 ^@ http://purl.uniprot.org/uniprot/E3J308 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14430 ^@ http://purl.uniprot.org/uniprot/E3J948 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19120 ^@ http://purl.uniprot.org/uniprot/E3J480 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30645 ^@ http://purl.uniprot.org/uniprot/E3J245 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/298654:FRAEUI1C_RS09875 ^@ http://purl.uniprot.org/uniprot/E3IV13 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/298654:FRAEUI1C_RS02190 ^@ http://purl.uniprot.org/uniprot/E3J9V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11775 ^@ http://purl.uniprot.org/uniprot/E3J0B9 ^@ Function ^@ Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/298654:FRAEUI1C_RS01540 ^@ http://purl.uniprot.org/uniprot/E3J7C0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/298654:FRAEUI1C_RS26280 ^@ http://purl.uniprot.org/uniprot/E3J884 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS07530 ^@ http://purl.uniprot.org/uniprot/E3J7G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06640 ^@ http://purl.uniprot.org/uniprot/E3J3Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24740 ^@ http://purl.uniprot.org/uniprot/E3J323 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS08925 ^@ http://purl.uniprot.org/uniprot/E3JBH9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS22120 ^@ http://purl.uniprot.org/uniprot/E3IUB5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS26850 ^@ http://purl.uniprot.org/uniprot/E3JAQ2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30855 ^@ http://purl.uniprot.org/uniprot/E3J396 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS06200 ^@ http://purl.uniprot.org/uniprot/E3J2D9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS24160 ^@ http://purl.uniprot.org/uniprot/E3J1Q1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/298654:FRAEUI1C_RS09390 ^@ http://purl.uniprot.org/uniprot/E3JCU9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/298654:FRAEUI1C_RS18590 ^@ http://purl.uniprot.org/uniprot/E3J2U2 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/298654:FRAEUI1C_RS25125 ^@ http://purl.uniprot.org/uniprot/E3J4D3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10355 ^@ http://purl.uniprot.org/uniprot/E3IWE5 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/298654:FRAEUI1C_RS28820 ^@ http://purl.uniprot.org/uniprot/E3IX11 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24695 ^@ http://purl.uniprot.org/uniprot/E3J314 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS04620 ^@ http://purl.uniprot.org/uniprot/E3IXH9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34110 ^@ http://purl.uniprot.org/uniprot/E3IUM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11635 ^@ http://purl.uniprot.org/uniprot/E3J092 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/298654:FRAEUI1C_RS27515 ^@ http://purl.uniprot.org/uniprot/E3JC67 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05940 ^@ http://purl.uniprot.org/uniprot/E3J181 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/298654:FRAEUI1C_RS01535 ^@ http://purl.uniprot.org/uniprot/E3J7B9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS01040 ^@ http://purl.uniprot.org/uniprot/E3J602 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07030 ^@ http://purl.uniprot.org/uniprot/E3J526 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05485 ^@ http://purl.uniprot.org/uniprot/E3J030 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/298654:FRAEUI1C_RS05580 ^@ http://purl.uniprot.org/uniprot/E3J050 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/298654:FRAEUI1C_RS03565 ^@ http://purl.uniprot.org/uniprot/E3ITN4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/298654:FRAEUI1C_RS31195 ^@ http://purl.uniprot.org/uniprot/E3J4J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS08590 ^@ http://purl.uniprot.org/uniprot/E3JA84 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS27765 ^@ http://purl.uniprot.org/uniprot/E3JDD9 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/298654:FRAEUI1C_RS03560 ^@ http://purl.uniprot.org/uniprot/E3ITN3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24200 ^@ http://purl.uniprot.org/uniprot/E3J1Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/298654:FRAEUI1C_RS27930 ^@ http://purl.uniprot.org/uniprot/E3JDH1 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS11235 ^@ http://purl.uniprot.org/uniprot/E3IZ15 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09990 ^@ http://purl.uniprot.org/uniprot/E3IV35 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08890 ^@ http://purl.uniprot.org/uniprot/E3JBH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00560 ^@ http://purl.uniprot.org/uniprot/E3J3J6 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/298654:FRAEUI1C_RS31500 ^@ http://purl.uniprot.org/uniprot/E3J5T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35505 ^@ http://purl.uniprot.org/uniprot/E3IYP9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS30110 ^@ http://purl.uniprot.org/uniprot/E3J0Y0 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/298654:FRAEUI1C_RS28665 ^@ http://purl.uniprot.org/uniprot/E3IVV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS15060 ^@ http://purl.uniprot.org/uniprot/E3JBM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06115 ^@ http://purl.uniprot.org/uniprot/E3J2C2 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03595 ^@ http://purl.uniprot.org/uniprot/E3ITP1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/298654:FRAEUI1C_RS12265 ^@ http://purl.uniprot.org/uniprot/E3J2I3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS20975 ^@ http://purl.uniprot.org/uniprot/E3JAN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05425 ^@ http://purl.uniprot.org/uniprot/E3J017 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS13940 ^@ http://purl.uniprot.org/uniprot/E3J7S6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04630 ^@ http://purl.uniprot.org/uniprot/E3IXI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS30775 ^@ http://purl.uniprot.org/uniprot/E3J380 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS05910 ^@ http://purl.uniprot.org/uniprot/E3J175 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23395 ^@ http://purl.uniprot.org/uniprot/E3IZD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00985 ^@ http://purl.uniprot.org/uniprot/E3J4W3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS05555 ^@ http://purl.uniprot.org/uniprot/E3J045 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS28800 ^@ http://purl.uniprot.org/uniprot/E3IX07 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/298654:FRAEUI1C_RS11395 ^@ http://purl.uniprot.org/uniprot/E3IZ47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/298654:FRAEUI1C_RS08485 ^@ http://purl.uniprot.org/uniprot/E3JA68 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/298654:FRAEUI1C_RS13865 ^@ http://purl.uniprot.org/uniprot/E3J7R1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24170 ^@ http://purl.uniprot.org/uniprot/E3J1Q3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS20560 ^@ http://purl.uniprot.org/uniprot/E3J9C5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS31150 ^@ http://purl.uniprot.org/uniprot/E3J4I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS32960 ^@ http://purl.uniprot.org/uniprot/E3JAY3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35485 ^@ http://purl.uniprot.org/uniprot/E3IYP5 ^@ Function|||Similarity ^@ Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine. http://togogenome.org/gene/298654:FRAEUI1C_RS05590 ^@ http://purl.uniprot.org/uniprot/E3J052 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/298654:FRAEUI1C_RS27155 ^@ http://purl.uniprot.org/uniprot/E3JAW3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS05105 ^@ http://purl.uniprot.org/uniprot/E3IYV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/298654:FRAEUI1C_RS21560 ^@ http://purl.uniprot.org/uniprot/E3JD60 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS12165 ^@ http://purl.uniprot.org/uniprot/E3J1F5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04710 ^@ http://purl.uniprot.org/uniprot/E3IXJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS01035 ^@ http://purl.uniprot.org/uniprot/E3J601 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/298654:FRAEUI1C_RS22305 ^@ http://purl.uniprot.org/uniprot/E3IVI1 ^@ Similarity ^@ Belongs to the bleomycin resistance protein family. http://togogenome.org/gene/298654:FRAEUI1C_RS00430 ^@ http://purl.uniprot.org/uniprot/E3J3H2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23785 ^@ http://purl.uniprot.org/uniprot/E3J0L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26200 ^@ http://purl.uniprot.org/uniprot/E3J868 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04915 ^@ http://purl.uniprot.org/uniprot/E3IYR7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/298654:FRAEUI1C_RS11810 ^@ http://purl.uniprot.org/uniprot/E3J0C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/298654:FRAEUI1C_RS30940 ^@ http://purl.uniprot.org/uniprot/E3J3B3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS35075 ^@ http://purl.uniprot.org/uniprot/E3IXD4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12220 ^@ http://purl.uniprot.org/uniprot/E3J1G7 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Catalyzes the reversible reductive amination of pyruvate to L-alanine. http://togogenome.org/gene/298654:FRAEUI1C_RS32335 ^@ http://purl.uniprot.org/uniprot/E3J8F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle GvpF/GvpL family.|||Gas vesicle|||Vesicle http://togogenome.org/gene/298654:FRAEUI1C_RS22430 ^@ http://purl.uniprot.org/uniprot/E3IVL0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS28040 ^@ http://purl.uniprot.org/uniprot/E3IUE1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15545 ^@ http://purl.uniprot.org/uniprot/E3JD05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09050 ^@ http://purl.uniprot.org/uniprot/E3JBK4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/298654:FRAEUI1C_RS29425 ^@ http://purl.uniprot.org/uniprot/E3IYG2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29310 ^@ http://purl.uniprot.org/uniprot/E3IYD9 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/298654:FRAEUI1C_RS28850 ^@ http://purl.uniprot.org/uniprot/E3IX17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/298654:FRAEUI1C_RS11625 ^@ http://purl.uniprot.org/uniprot/E3J090 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS06155 ^@ http://purl.uniprot.org/uniprot/E3J2D0 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16085 ^@ http://purl.uniprot.org/uniprot/E3IU54 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30865 ^@ http://purl.uniprot.org/uniprot/E3J398 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/298654:FRAEUI1C_RS28495 ^@ http://purl.uniprot.org/uniprot/E3IVR5 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/298654:FRAEUI1C_RS17975 ^@ http://purl.uniprot.org/uniprot/E3J0K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21565 ^@ http://purl.uniprot.org/uniprot/E3JD61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07545 ^@ http://purl.uniprot.org/uniprot/E3J7H1 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/298654:FRAEUI1C_RS25350 ^@ http://purl.uniprot.org/uniprot/E3J5L0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/298654:FRAEUI1C_RS30810 ^@ http://purl.uniprot.org/uniprot/E3J387 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/298654:FRAEUI1C_RS03260 ^@ http://purl.uniprot.org/uniprot/E3JCN8 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/298654:FRAEUI1C_RS06825 ^@ http://purl.uniprot.org/uniprot/E3J4Y4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17140 ^@ http://purl.uniprot.org/uniprot/E3IY03 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS19565 ^@ http://purl.uniprot.org/uniprot/E3J6M4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS06245 ^@ http://purl.uniprot.org/uniprot/E3J2E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07395 ^@ http://purl.uniprot.org/uniprot/E3J6B9 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28730 ^@ http://purl.uniprot.org/uniprot/E3IVW3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/298654:FRAEUI1C_RS20315 ^@ http://purl.uniprot.org/uniprot/E3J976 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LigB/MhpB extradiol dioxygenase family.|||Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.|||Homotetramer. http://togogenome.org/gene/298654:FRAEUI1C_RS00740 ^@ http://purl.uniprot.org/uniprot/E3J4R4 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/298654:FRAEUI1C_RS10170 ^@ http://purl.uniprot.org/uniprot/E3IV71 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26500 ^@ http://purl.uniprot.org/uniprot/E3J9F7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS17130 ^@ http://purl.uniprot.org/uniprot/E3IY01 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS21030 ^@ http://purl.uniprot.org/uniprot/E3JAP5 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS30345 ^@ http://purl.uniprot.org/uniprot/E3J1Y5 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/298654:FRAEUI1C_RS33125 ^@ http://purl.uniprot.org/uniprot/E3JB17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/298654:FRAEUI1C_RS21185 ^@ http://purl.uniprot.org/uniprot/E3JBV8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24605 ^@ http://purl.uniprot.org/uniprot/E3J2Z6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11960 ^@ http://purl.uniprot.org/uniprot/E3J1B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08695 ^@ http://purl.uniprot.org/uniprot/E3JBD3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33035 ^@ http://purl.uniprot.org/uniprot/E3JAZ8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS32810 ^@ http://purl.uniprot.org/uniprot/E3J9S3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06010 ^@ http://purl.uniprot.org/uniprot/E3J2A1 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30805 ^@ http://purl.uniprot.org/uniprot/E3J386 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/298654:FRAEUI1C_RS03880 ^@ http://purl.uniprot.org/uniprot/E3IUX3 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/298654:FRAEUI1C_RS09725 ^@ http://purl.uniprot.org/uniprot/E3ITV6 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/298654:FRAEUI1C_RS05370 ^@ http://purl.uniprot.org/uniprot/E3J006 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/298654:FRAEUI1C_RS17980 ^@ http://purl.uniprot.org/uniprot/E3J0K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06625 ^@ http://purl.uniprot.org/uniprot/E3J3Q6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS05625 ^@ http://purl.uniprot.org/uniprot/E3J118 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/298654:FRAEUI1C_RS28625 ^@ http://purl.uniprot.org/uniprot/E3IVU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30950 ^@ http://purl.uniprot.org/uniprot/E3J3B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS23515 ^@ http://purl.uniprot.org/uniprot/E3IZG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15180 ^@ http://purl.uniprot.org/uniprot/E3JBQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/298654:FRAEUI1C_RS06795 ^@ http://purl.uniprot.org/uniprot/E3J4X7 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08135 ^@ http://purl.uniprot.org/uniprot/E3J8W6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18425 ^@ http://purl.uniprot.org/uniprot/E3J2Q9 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS22500 ^@ http://purl.uniprot.org/uniprot/E3IVM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11055 ^@ http://purl.uniprot.org/uniprot/E3IYX8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/298654:FRAEUI1C_RS28455 ^@ http://purl.uniprot.org/uniprot/E3IVQ7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25185 ^@ http://purl.uniprot.org/uniprot/E3J4E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11560 ^@ http://purl.uniprot.org/uniprot/E3J077 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS22350 ^@ http://purl.uniprot.org/uniprot/E3IVJ0 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/298654:FRAEUI1C_RS24210 ^@ http://purl.uniprot.org/uniprot/E3J1R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS07155 ^@ http://purl.uniprot.org/uniprot/E3J675 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS17710 ^@ http://purl.uniprot.org/uniprot/E3J0E7 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02655 ^@ http://purl.uniprot.org/uniprot/E3JB85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS39810 ^@ http://purl.uniprot.org/uniprot/E3IUF1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS07255 ^@ http://purl.uniprot.org/uniprot/E3J693 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS07650 ^@ http://purl.uniprot.org/uniprot/E3J7J3 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25285 ^@ http://purl.uniprot.org/uniprot/E3J4G5 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/298654:FRAEUI1C_RS10965 ^@ http://purl.uniprot.org/uniprot/E3IXT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat shock protein 70 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18080 ^@ http://purl.uniprot.org/uniprot/E3J1I2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/298654:FRAEUI1C_RS16885 ^@ http://purl.uniprot.org/uniprot/E3IXV2 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/298654:FRAEUI1C_RS10190 ^@ http://purl.uniprot.org/uniprot/E3IV75 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS11480 ^@ http://purl.uniprot.org/uniprot/E3J065 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS09755 ^@ http://purl.uniprot.org/uniprot/E3ITW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33785 ^@ http://purl.uniprot.org/uniprot/E3JDK7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04910 ^@ http://purl.uniprot.org/uniprot/E3IYR6 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/298654:FRAEUI1C_RS09370 ^@ http://purl.uniprot.org/uniprot/E3JCU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16790 ^@ http://purl.uniprot.org/uniprot/E3IWQ8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS31820 ^@ http://purl.uniprot.org/uniprot/E3J718 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21655 ^@ http://purl.uniprot.org/uniprot/E3JD79 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS33245 ^@ http://purl.uniprot.org/uniprot/E3JB42 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS06635 ^@ http://purl.uniprot.org/uniprot/E3J3Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12655 ^@ http://purl.uniprot.org/uniprot/E3J3U1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS01845 ^@ http://purl.uniprot.org/uniprot/E3J8L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS27490 ^@ http://purl.uniprot.org/uniprot/E3JC62 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12110 ^@ http://purl.uniprot.org/uniprot/E3J1E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15615 ^@ http://purl.uniprot.org/uniprot/E3JD19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16635 ^@ http://purl.uniprot.org/uniprot/E3IWM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25565 ^@ http://purl.uniprot.org/uniprot/E3J5Q3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS24420 ^@ http://purl.uniprot.org/uniprot/E3J1V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS22030 ^@ http://purl.uniprot.org/uniprot/E3IU96 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS09430 ^@ http://purl.uniprot.org/uniprot/E3JCV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13045 ^@ http://purl.uniprot.org/uniprot/E3J553 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30460 ^@ http://purl.uniprot.org/uniprot/E3J208 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS10230 ^@ http://purl.uniprot.org/uniprot/E3IV83 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS22725 ^@ http://purl.uniprot.org/uniprot/E3IWV2 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16980 ^@ http://purl.uniprot.org/uniprot/E3IXX1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS29790 ^@ http://purl.uniprot.org/uniprot/E3IZR2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31015 ^@ http://purl.uniprot.org/uniprot/E3J3C8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/298654:FRAEUI1C_RS33940 ^@ http://purl.uniprot.org/uniprot/E3JDN9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/298654:FRAEUI1C_RS18875 ^@ http://purl.uniprot.org/uniprot/E3J430 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10920 ^@ http://purl.uniprot.org/uniprot/E3IXS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/298654:FRAEUI1C_RS18895 ^@ http://purl.uniprot.org/uniprot/E3J435 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16985 ^@ http://purl.uniprot.org/uniprot/E3IXX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30105 ^@ http://purl.uniprot.org/uniprot/E3J0X9 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/298654:FRAEUI1C_RS02695 ^@ http://purl.uniprot.org/uniprot/E3JB93 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12200 ^@ http://purl.uniprot.org/uniprot/E3J1G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18010 ^@ http://purl.uniprot.org/uniprot/E3J0K7 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22990 ^@ http://purl.uniprot.org/uniprot/E3IY32 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS02570 ^@ http://purl.uniprot.org/uniprot/E3JB68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24535 ^@ http://purl.uniprot.org/uniprot/E3J2Y3 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/298654:FRAEUI1C_RS00470 ^@ http://purl.uniprot.org/uniprot/E3J3H9 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/298654:FRAEUI1C_RS31065 ^@ http://purl.uniprot.org/uniprot/E3J4G8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS01395 ^@ http://purl.uniprot.org/uniprot/E3J791 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS31010 ^@ http://purl.uniprot.org/uniprot/E3J3C7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/298654:FRAEUI1C_RS27580 ^@ http://purl.uniprot.org/uniprot/E3JC80 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05675 ^@ http://purl.uniprot.org/uniprot/E3J128 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/298654:FRAEUI1C_RS32115 ^@ http://purl.uniprot.org/uniprot/E3J775 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11790 ^@ http://purl.uniprot.org/uniprot/E3J0C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS03005 ^@ http://purl.uniprot.org/uniprot/E3JCI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29285 ^@ http://purl.uniprot.org/uniprot/E3IYD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18195 ^@ http://purl.uniprot.org/uniprot/E3J1K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25845 ^@ http://purl.uniprot.org/uniprot/E3J6X1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/298654:FRAEUI1C_RS17750 ^@ http://purl.uniprot.org/uniprot/E3J0F5 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS16590 ^@ http://purl.uniprot.org/uniprot/E3IWL9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00880 ^@ http://purl.uniprot.org/uniprot/E3J4U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10335 ^@ http://purl.uniprot.org/uniprot/E3IWE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS03160 ^@ http://purl.uniprot.org/uniprot/E3JCL7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11060 ^@ http://purl.uniprot.org/uniprot/E3IYX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/298654:FRAEUI1C_RS22505 ^@ http://purl.uniprot.org/uniprot/E3IVM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26225 ^@ http://purl.uniprot.org/uniprot/E3J873 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS07510 ^@ http://purl.uniprot.org/uniprot/E3J6E6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30660 ^@ http://purl.uniprot.org/uniprot/E3J248 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/298654:FRAEUI1C_RS34070 ^@ http://purl.uniprot.org/uniprot/E3IUL8 ^@ Similarity ^@ Belongs to the DnaX/STICHEL family. http://togogenome.org/gene/298654:FRAEUI1C_RS23475 ^@ http://purl.uniprot.org/uniprot/E3IZF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30785 ^@ http://purl.uniprot.org/uniprot/E3J382 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/298654:FRAEUI1C_RS35680 ^@ http://purl.uniprot.org/uniprot/E3IZW3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS11940 ^@ http://purl.uniprot.org/uniprot/E3J1B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS04715 ^@ http://purl.uniprot.org/uniprot/E3IXJ8 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03195 ^@ http://purl.uniprot.org/uniprot/E3JCM4 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS02865 ^@ http://purl.uniprot.org/uniprot/E3JBC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS01650 ^@ http://purl.uniprot.org/uniprot/E3J7E1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/298654:FRAEUI1C_RS29490 ^@ http://purl.uniprot.org/uniprot/E3IYH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30475 ^@ http://purl.uniprot.org/uniprot/E3J211 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19205 ^@ http://purl.uniprot.org/uniprot/E3J5D3 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/298654:FRAEUI1C_RS08155 ^@ http://purl.uniprot.org/uniprot/E3J8X0 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/298654:FRAEUI1C_RS16070 ^@ http://purl.uniprot.org/uniprot/E3IU51 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10840 ^@ http://purl.uniprot.org/uniprot/E3IXQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05715 ^@ http://purl.uniprot.org/uniprot/E3J136 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS10985 ^@ http://purl.uniprot.org/uniprot/E3IXT7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS07785 ^@ http://purl.uniprot.org/uniprot/E3J7M1 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/298654:FRAEUI1C_RS15955 ^@ http://purl.uniprot.org/uniprot/E3IU27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07825 ^@ http://purl.uniprot.org/uniprot/E3J7M9 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29690 ^@ http://purl.uniprot.org/uniprot/E3IZP2 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03420 ^@ http://purl.uniprot.org/uniprot/E3ITK5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS31740 ^@ http://purl.uniprot.org/uniprot/E3J5Y4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS06555 ^@ http://purl.uniprot.org/uniprot/E3J3P2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS26725 ^@ http://purl.uniprot.org/uniprot/E3J9K2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS01925 ^@ http://purl.uniprot.org/uniprot/E3J8M6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS18625 ^@ http://purl.uniprot.org/uniprot/E3J2U8 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/298654:FRAEUI1C_RS31725 ^@ http://purl.uniprot.org/uniprot/E3J5Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS34815 ^@ http://purl.uniprot.org/uniprot/E3IX84 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26335 ^@ http://purl.uniprot.org/uniprot/E3J895 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27660 ^@ http://purl.uniprot.org/uniprot/E3JDB9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30270 ^@ http://purl.uniprot.org/uniprot/E3J111 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS23135 ^@ http://purl.uniprot.org/uniprot/E3IY60 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS21130 ^@ http://purl.uniprot.org/uniprot/E3JBU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16410 ^@ http://purl.uniprot.org/uniprot/E3IVE9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24530 ^@ http://purl.uniprot.org/uniprot/E3J2Y2 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/298654:FRAEUI1C_RS33970 ^@ http://purl.uniprot.org/uniprot/E3JDP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS17000 ^@ http://purl.uniprot.org/uniprot/E3IXX5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08430 ^@ http://purl.uniprot.org/uniprot/E3JA57 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/298654:FRAEUI1C_RS31135 ^@ http://purl.uniprot.org/uniprot/E3J4I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18055 ^@ http://purl.uniprot.org/uniprot/E3J1H7 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/298654:FRAEUI1C_RS29885 ^@ http://purl.uniprot.org/uniprot/E3IZT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/298654:FRAEUI1C_RS09825 ^@ http://purl.uniprot.org/uniprot/E3ITX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS11490 ^@ http://purl.uniprot.org/uniprot/E3J067 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/298654:FRAEUI1C_RS00375 ^@ http://purl.uniprot.org/uniprot/E3J3G1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/298654:FRAEUI1C_RS19215 ^@ http://purl.uniprot.org/uniprot/E3J5D5 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/298654:FRAEUI1C_RS11815 ^@ http://purl.uniprot.org/uniprot/E3J0C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS21660 ^@ http://purl.uniprot.org/uniprot/E3JD80 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS07070 ^@ http://purl.uniprot.org/uniprot/E3J534 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30990 ^@ http://purl.uniprot.org/uniprot/E3J3C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/298654:FRAEUI1C_RS22290 ^@ http://purl.uniprot.org/uniprot/E3IVH8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS10210 ^@ http://purl.uniprot.org/uniprot/E3IV79 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS04210 ^@ http://purl.uniprot.org/uniprot/E3IW75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03735 ^@ http://purl.uniprot.org/uniprot/E3IUU4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30300 ^@ http://purl.uniprot.org/uniprot/E3J1X6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS22955 ^@ http://purl.uniprot.org/uniprot/E3IWZ9 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/298654:FRAEUI1C_RS12630 ^@ http://purl.uniprot.org/uniprot/E3J3T6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS04900 ^@ http://purl.uniprot.org/uniprot/E3IYR4 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/298654:FRAEUI1C_RS02205 ^@ http://purl.uniprot.org/uniprot/E3J9W2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS25515 ^@ http://purl.uniprot.org/uniprot/E3J5P3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/298654:FRAEUI1C_RS27165 ^@ http://purl.uniprot.org/uniprot/E3JAW5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14710 ^@ http://purl.uniprot.org/uniprot/E3JAC9 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/298654:FRAEUI1C_RS18635 ^@ http://purl.uniprot.org/uniprot/E3J2V0 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/298654:FRAEUI1C_RS18685 ^@ http://purl.uniprot.org/uniprot/E3J2W0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS19390 ^@ http://purl.uniprot.org/uniprot/E3J5G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13785 ^@ http://purl.uniprot.org/uniprot/E3J7P5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30545 ^@ http://purl.uniprot.org/uniprot/E3J225 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/298654:FRAEUI1C_RS03770 ^@ http://purl.uniprot.org/uniprot/E3IUV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/298654:FRAEUI1C_RS08270 ^@ http://purl.uniprot.org/uniprot/E3J8Z3 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08185 ^@ http://purl.uniprot.org/uniprot/E3J8X6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28715 ^@ http://purl.uniprot.org/uniprot/E3IVW0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS34325 ^@ http://purl.uniprot.org/uniprot/E3IUS0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS16100 ^@ http://purl.uniprot.org/uniprot/E3IU57 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09880 ^@ http://purl.uniprot.org/uniprot/E3IV14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/298654:FRAEUI1C_RS02690 ^@ http://purl.uniprot.org/uniprot/E3JB92 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24735 ^@ http://purl.uniprot.org/uniprot/E3J322 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS31140 ^@ http://purl.uniprot.org/uniprot/E3J4I3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10115 ^@ http://purl.uniprot.org/uniprot/E3IV60 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17035 ^@ http://purl.uniprot.org/uniprot/E3IXY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS25905 ^@ http://purl.uniprot.org/uniprot/E3J6Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14585 ^@ http://purl.uniprot.org/uniprot/E3JAA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS19575 ^@ http://purl.uniprot.org/uniprot/E3J6M6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06165 ^@ http://purl.uniprot.org/uniprot/E3J2D2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS41265 ^@ http://purl.uniprot.org/uniprot/E3IZF4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24310 ^@ http://purl.uniprot.org/uniprot/E3J1T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS22520 ^@ http://purl.uniprot.org/uniprot/E3IVM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10980 ^@ http://purl.uniprot.org/uniprot/E3IXT6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/298654:FRAEUI1C_RS22560 ^@ http://purl.uniprot.org/uniprot/E3IVN6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08855 ^@ http://purl.uniprot.org/uniprot/E3JBG5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS41520 ^@ http://purl.uniprot.org/uniprot/E3IZW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33075 ^@ http://purl.uniprot.org/uniprot/E3JB07 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS01555 ^@ http://purl.uniprot.org/uniprot/E3J7C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/298654:FRAEUI1C_RS33595 ^@ http://purl.uniprot.org/uniprot/E3JCE6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS02940 ^@ http://purl.uniprot.org/uniprot/E3JCH2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06345 ^@ http://purl.uniprot.org/uniprot/E3J2G8 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35620 ^@ http://purl.uniprot.org/uniprot/E3IZV1 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05570 ^@ http://purl.uniprot.org/uniprot/E3J048 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/298654:FRAEUI1C_RS05320 ^@ http://purl.uniprot.org/uniprot/E3IZZ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS32210 ^@ http://purl.uniprot.org/uniprot/E3J8C6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS03445 ^@ http://purl.uniprot.org/uniprot/E3ITL0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS08500 ^@ http://purl.uniprot.org/uniprot/E3JA71 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS23180 ^@ http://purl.uniprot.org/uniprot/E3IY69 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS02330 ^@ http://purl.uniprot.org/uniprot/E3J9Y8 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/298654:FRAEUI1C_RS24235 ^@ http://purl.uniprot.org/uniprot/E3J1R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/298654:FRAEUI1C_RS33700 ^@ http://purl.uniprot.org/uniprot/E3JDJ0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/298654:FRAEUI1C_RS27830 ^@ http://purl.uniprot.org/uniprot/E3JDF2 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21975 ^@ http://purl.uniprot.org/uniprot/E3IU86 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21350 ^@ http://purl.uniprot.org/uniprot/E3JBZ1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS32760 ^@ http://purl.uniprot.org/uniprot/E3J9R3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22510 ^@ http://purl.uniprot.org/uniprot/E3IVM6 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30900 ^@ http://purl.uniprot.org/uniprot/E3J3A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS27325 ^@ http://purl.uniprot.org/uniprot/E3JC28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14210 ^@ http://purl.uniprot.org/uniprot/E3J905 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26600 ^@ http://purl.uniprot.org/uniprot/E3J9H7 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS29470 ^@ http://purl.uniprot.org/uniprot/E3IYH1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33120 ^@ http://purl.uniprot.org/uniprot/E3JB16 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/298654:FRAEUI1C_RS05760 ^@ http://purl.uniprot.org/uniprot/E3J145 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/298654:FRAEUI1C_RS35495 ^@ http://purl.uniprot.org/uniprot/E3IYP7 ^@ Function ^@ Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/298654:FRAEUI1C_RS01730 ^@ http://purl.uniprot.org/uniprot/E3J7F8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/298654:FRAEUI1C_RS02650 ^@ http://purl.uniprot.org/uniprot/E3JB84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03240 ^@ http://purl.uniprot.org/uniprot/E3JCN4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/298654:FRAEUI1C_RS28645 ^@ http://purl.uniprot.org/uniprot/E3IVU6 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00020 ^@ http://purl.uniprot.org/uniprot/E3J253 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/298654:FRAEUI1C_RS05405 ^@ http://purl.uniprot.org/uniprot/E3J013 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS05430 ^@ http://purl.uniprot.org/uniprot/E3J018 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS15075 ^@ http://purl.uniprot.org/uniprot/E3JBN2 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS20380 ^@ http://purl.uniprot.org/uniprot/E3J989 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30325 ^@ http://purl.uniprot.org/uniprot/E3J1Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07195 ^@ http://purl.uniprot.org/uniprot/E3J682 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26860 ^@ http://purl.uniprot.org/uniprot/E3JAQ4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19225 ^@ http://purl.uniprot.org/uniprot/E3J5D7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS17550 ^@ http://purl.uniprot.org/uniprot/E3IZB3 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34125 ^@ http://purl.uniprot.org/uniprot/E3IUM9 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/298654:FRAEUI1C_RS23110 ^@ http://purl.uniprot.org/uniprot/E3IY55 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/298654:FRAEUI1C_RS07250 ^@ http://purl.uniprot.org/uniprot/E3J692 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11310 ^@ http://purl.uniprot.org/uniprot/E3IZ30 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS33010 ^@ http://purl.uniprot.org/uniprot/E3JAZ3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS01530 ^@ http://purl.uniprot.org/uniprot/E3J7B8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/298654:FRAEUI1C_RS22130 ^@ http://purl.uniprot.org/uniprot/E3IUB7 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS08480 ^@ http://purl.uniprot.org/uniprot/E3JA67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS28670 ^@ http://purl.uniprot.org/uniprot/E3IVV1 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS03965 ^@ http://purl.uniprot.org/uniprot/E3IUY8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS02015 ^@ http://purl.uniprot.org/uniprot/E3J8P4 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS36255 ^@ http://purl.uniprot.org/uniprot/E3J7T8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS13410 ^@ http://purl.uniprot.org/uniprot/E3J5C4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08435 ^@ http://purl.uniprot.org/uniprot/E3JA58 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS16850 ^@ http://purl.uniprot.org/uniprot/E3IWS0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS13870 ^@ http://purl.uniprot.org/uniprot/E3J7R2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15510 ^@ http://purl.uniprot.org/uniprot/E3JCZ8 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18350 ^@ http://purl.uniprot.org/uniprot/E3J1N6 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/298654:FRAEUI1C_RS18720 ^@ http://purl.uniprot.org/uniprot/E3J2W7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08300 ^@ http://purl.uniprot.org/uniprot/E3JA30 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/298654:FRAEUI1C_RS30020 ^@ http://purl.uniprot.org/uniprot/E3J0W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/298654:FRAEUI1C_RS15205 ^@ http://purl.uniprot.org/uniprot/E3JBQ7 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS04170 ^@ http://purl.uniprot.org/uniprot/E3IW67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/298654:FRAEUI1C_RS03000 ^@ http://purl.uniprot.org/uniprot/E3JCI6 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28095 ^@ http://purl.uniprot.org/uniprot/E3IUF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05210 ^@ http://purl.uniprot.org/uniprot/E3IYX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/298654:FRAEUI1C_RS36770 ^@ http://purl.uniprot.org/uniprot/E3IX32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WhiB family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS05560 ^@ http://purl.uniprot.org/uniprot/E3J046 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/298654:FRAEUI1C_RS17215 ^@ http://purl.uniprot.org/uniprot/E3IY18 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21820 ^@ http://purl.uniprot.org/uniprot/E3JDA8 ^@ Caution|||Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS01890 ^@ http://purl.uniprot.org/uniprot/E3J8L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.|||Homooctamer.|||Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. http://togogenome.org/gene/298654:FRAEUI1C_RS10000 ^@ http://purl.uniprot.org/uniprot/E3IV37 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS25415 ^@ http://purl.uniprot.org/uniprot/E3J5M3 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS15055 ^@ http://purl.uniprot.org/uniprot/E3JBM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05585 ^@ http://purl.uniprot.org/uniprot/E3J051 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS26505 ^@ http://purl.uniprot.org/uniprot/E3J9F8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS24185 ^@ http://purl.uniprot.org/uniprot/E3J1Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS41000 ^@ http://purl.uniprot.org/uniprot/E3J6F9 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/298654:FRAEUI1C_RS15280 ^@ http://purl.uniprot.org/uniprot/E3JBS0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS13115 ^@ http://purl.uniprot.org/uniprot/E3J567 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS16560 ^@ http://purl.uniprot.org/uniprot/E3IWL3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30880 ^@ http://purl.uniprot.org/uniprot/E3J3A1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/298654:FRAEUI1C_RS18740 ^@ http://purl.uniprot.org/uniprot/E3J2X1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS23615 ^@ http://purl.uniprot.org/uniprot/E3IZI0 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24135 ^@ http://purl.uniprot.org/uniprot/E3J0T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/298654:FRAEUI1C_RS24365 ^@ http://purl.uniprot.org/uniprot/E3J1U1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23925 ^@ http://purl.uniprot.org/uniprot/E3J0P3 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS18135 ^@ http://purl.uniprot.org/uniprot/E3J1J3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS20515 ^@ http://purl.uniprot.org/uniprot/E3J9B6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32090 ^@ http://purl.uniprot.org/uniprot/E3J769 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23460 ^@ http://purl.uniprot.org/uniprot/E3IZF0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/298654:FRAEUI1C_RS30595 ^@ http://purl.uniprot.org/uniprot/E3J235 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS20950 ^@ http://purl.uniprot.org/uniprot/E3JAM9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/298654:FRAEUI1C_RS24010 ^@ http://purl.uniprot.org/uniprot/E3J0R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30115 ^@ http://purl.uniprot.org/uniprot/E3J0Y1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25525 ^@ http://purl.uniprot.org/uniprot/E3J5P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19250 ^@ http://purl.uniprot.org/uniprot/E3J5E2 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33825 ^@ http://purl.uniprot.org/uniprot/E3JDL6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS07710 ^@ http://purl.uniprot.org/uniprot/E3J7K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27585 ^@ http://purl.uniprot.org/uniprot/E3JC81 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33905 ^@ http://purl.uniprot.org/uniprot/E3JDN2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09395 ^@ http://purl.uniprot.org/uniprot/E3JCV0 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33395 ^@ http://purl.uniprot.org/uniprot/E3JCA4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/298654:FRAEUI1C_RS16415 ^@ http://purl.uniprot.org/uniprot/E3IVF0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30925 ^@ http://purl.uniprot.org/uniprot/E3J3B0 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/298654:FRAEUI1C_RS01685 ^@ http://purl.uniprot.org/uniprot/E3J7E8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/298654:FRAEUI1C_RS28025 ^@ http://purl.uniprot.org/uniprot/E3IUD8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS18570 ^@ http://purl.uniprot.org/uniprot/E3J2T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/298654:FRAEUI1C_RS29060 ^@ http://purl.uniprot.org/uniprot/E3IX63 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS06320 ^@ http://purl.uniprot.org/uniprot/E3J2G3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS00280 ^@ http://purl.uniprot.org/uniprot/E3J3E2 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS10810 ^@ http://purl.uniprot.org/uniprot/E3IXQ2 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS17430 ^@ http://purl.uniprot.org/uniprot/E3IZ89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS15965 ^@ http://purl.uniprot.org/uniprot/E3IU29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS11840 ^@ http://purl.uniprot.org/uniprot/E3J194 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/298654:FRAEUI1C_RS30845 ^@ http://purl.uniprot.org/uniprot/E3J394 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/298654:FRAEUI1C_RS18375 ^@ http://purl.uniprot.org/uniprot/E3J1P1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS05515 ^@ http://purl.uniprot.org/uniprot/E3J036 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS14075 ^@ http://purl.uniprot.org/uniprot/E3J7V3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34335 ^@ http://purl.uniprot.org/uniprot/E3IUS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30760 ^@ http://purl.uniprot.org/uniprot/E3J377 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/298654:FRAEUI1C_RS16570 ^@ http://purl.uniprot.org/uniprot/E3IWL5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS05440 ^@ http://purl.uniprot.org/uniprot/E3J020 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/298654:FRAEUI1C_RS05060 ^@ http://purl.uniprot.org/uniprot/E3IYU4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS09065 ^@ http://purl.uniprot.org/uniprot/E3JBK7 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/298654:FRAEUI1C_RS00245 ^@ http://purl.uniprot.org/uniprot/E3J298 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05490 ^@ http://purl.uniprot.org/uniprot/E3J031 ^@ Function|||Subunit ^@ Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/298654:FRAEUI1C_RS31125 ^@ http://purl.uniprot.org/uniprot/E3J4I0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15110 ^@ http://purl.uniprot.org/uniprot/E3JBN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial phospholipase C family.|||cell wall http://togogenome.org/gene/298654:FRAEUI1C_RS31335 ^@ http://purl.uniprot.org/uniprot/E3J4M2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS26440 ^@ http://purl.uniprot.org/uniprot/E3J8B6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS29910 ^@ http://purl.uniprot.org/uniprot/E3J0U0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/298654:FRAEUI1C_RS05535 ^@ http://purl.uniprot.org/uniprot/E3J041 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/298654:FRAEUI1C_RS20735 ^@ http://purl.uniprot.org/uniprot/E3JAI6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22345 ^@ http://purl.uniprot.org/uniprot/E3IVI9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS05660 ^@ http://purl.uniprot.org/uniprot/E3J125 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/298654:FRAEUI1C_RS24375 ^@ http://purl.uniprot.org/uniprot/E3J1U3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS31175 ^@ http://purl.uniprot.org/uniprot/E3J4J0 ^@ Similarity ^@ Belongs to the complex I 24 kDa subunit family. http://togogenome.org/gene/298654:FRAEUI1C_RS25355 ^@ http://purl.uniprot.org/uniprot/E3J5L1 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS07055 ^@ http://purl.uniprot.org/uniprot/E3J531 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS14915 ^@ http://purl.uniprot.org/uniprot/E3JAH0 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS10325 ^@ http://purl.uniprot.org/uniprot/E3IWD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31235 ^@ http://purl.uniprot.org/uniprot/E3J4K2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05345 ^@ http://purl.uniprot.org/uniprot/E3J001 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/298654:FRAEUI1C_RS17725 ^@ http://purl.uniprot.org/uniprot/E3J0F0 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15475 ^@ http://purl.uniprot.org/uniprot/E3JCZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS03055 ^@ http://purl.uniprot.org/uniprot/E3JCJ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS20245 ^@ http://purl.uniprot.org/uniprot/E3J833 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28220 ^@ http://purl.uniprot.org/uniprot/E3IUH7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS09710 ^@ http://purl.uniprot.org/uniprot/E3ITV3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/298654:FRAEUI1C_RS29115 ^@ http://purl.uniprot.org/uniprot/E3IX74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08670 ^@ http://purl.uniprot.org/uniprot/E3JAA0 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS16080 ^@ http://purl.uniprot.org/uniprot/E3IU53 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS34265 ^@ http://purl.uniprot.org/uniprot/E3IUQ8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS19590 ^@ http://purl.uniprot.org/uniprot/E3J6M9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS21530 ^@ http://purl.uniprot.org/uniprot/E3JD54 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/298654:FRAEUI1C_RS16765 ^@ http://purl.uniprot.org/uniprot/E3IWQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS32510 ^@ http://purl.uniprot.org/uniprot/E3J8I6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS07670 ^@ http://purl.uniprot.org/uniprot/E3J7J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14925 ^@ http://purl.uniprot.org/uniprot/E3JAH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS30495 ^@ http://purl.uniprot.org/uniprot/E3J215 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/298654:FRAEUI1C_RS33175 ^@ http://purl.uniprot.org/uniprot/E3JB28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Belongs to the glycosyltransferase 2 family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14790 ^@ http://purl.uniprot.org/uniprot/E3JAE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/298654:FRAEUI1C_RS36010 ^@ http://purl.uniprot.org/uniprot/E3J8Z0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/298654:FRAEUI1C_RS18250 ^@ http://purl.uniprot.org/uniprot/E3J1L6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS01000 ^@ http://purl.uniprot.org/uniprot/E3J4W6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/298654:FRAEUI1C_RS17815 ^@ http://purl.uniprot.org/uniprot/E3J0G8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35415 ^@ http://purl.uniprot.org/uniprot/E3IYN1 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS12130 ^@ http://purl.uniprot.org/uniprot/E3J1F0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24115 ^@ http://purl.uniprot.org/uniprot/E3J0T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24140 ^@ http://purl.uniprot.org/uniprot/E3J0T6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS09600 ^@ http://purl.uniprot.org/uniprot/E3ITT4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS25750 ^@ http://purl.uniprot.org/uniprot/E3J6V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS18060 ^@ http://purl.uniprot.org/uniprot/E3J1H8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/298654:FRAEUI1C_RS01825 ^@ http://purl.uniprot.org/uniprot/E3J8K6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS03320 ^@ http://purl.uniprot.org/uniprot/E3ITI8 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/298654:FRAEUI1C_RS04945 ^@ http://purl.uniprot.org/uniprot/E3IYS3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/298654:FRAEUI1C_RS08015 ^@ http://purl.uniprot.org/uniprot/E3J8U4 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11065 ^@ http://purl.uniprot.org/uniprot/E3IYY0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS33585 ^@ http://purl.uniprot.org/uniprot/E3JCE3 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05990 ^@ http://purl.uniprot.org/uniprot/E3J191 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/298654:FRAEUI1C_RS23350 ^@ http://purl.uniprot.org/uniprot/E3IYA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09105 ^@ http://purl.uniprot.org/uniprot/E3JCP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS07050 ^@ http://purl.uniprot.org/uniprot/E3J530 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS30575 ^@ http://purl.uniprot.org/uniprot/E3J231 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS16450 ^@ http://purl.uniprot.org/uniprot/E3IVF7 ^@ Caution|||Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/298654:FRAEUI1C_RS08295 ^@ http://purl.uniprot.org/uniprot/E3JA29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/298654:FRAEUI1C_RS26375 ^@ http://purl.uniprot.org/uniprot/E3J8A3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS02370 ^@ http://purl.uniprot.org/uniprot/E3J9Z6 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/298654:FRAEUI1C_RS23725 ^@ http://purl.uniprot.org/uniprot/E3IZK1 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35355 ^@ http://purl.uniprot.org/uniprot/E3IYL9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS19520 ^@ http://purl.uniprot.org/uniprot/E3J5J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35325 ^@ http://purl.uniprot.org/uniprot/E3IYL3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS36600 ^@ http://purl.uniprot.org/uniprot/E3IY70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/298654:FRAEUI1C_RS16095 ^@ http://purl.uniprot.org/uniprot/E3IU56 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS08795 ^@ http://purl.uniprot.org/uniprot/E3JBF3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/298654:FRAEUI1C_RS22040 ^@ http://purl.uniprot.org/uniprot/E3IU98 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS10880 ^@ http://purl.uniprot.org/uniprot/E3IXR6 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05050 ^@ http://purl.uniprot.org/uniprot/E3IYU2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS35100 ^@ http://purl.uniprot.org/uniprot/E3IXD9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS28845 ^@ http://purl.uniprot.org/uniprot/E3IX16 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/298654:FRAEUI1C_RS11590 ^@ http://purl.uniprot.org/uniprot/E3J083 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS13780 ^@ http://purl.uniprot.org/uniprot/E3J7P4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09335 ^@ http://purl.uniprot.org/uniprot/E3JCT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS32080 ^@ http://purl.uniprot.org/uniprot/E3J767 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/298654:FRAEUI1C_RS22960 ^@ http://purl.uniprot.org/uniprot/E3IX00 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17085 ^@ http://purl.uniprot.org/uniprot/E3IXZ2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/298654:FRAEUI1C_RS08050 ^@ http://purl.uniprot.org/uniprot/E3J8V1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/298654:FRAEUI1C_RS02250 ^@ http://purl.uniprot.org/uniprot/E3J9X1 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23050 ^@ http://purl.uniprot.org/uniprot/E3IY44 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05350 ^@ http://purl.uniprot.org/uniprot/E3J002 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/298654:FRAEUI1C_RS20850 ^@ http://purl.uniprot.org/uniprot/E3JAK9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15960 ^@ http://purl.uniprot.org/uniprot/E3IU28 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/298654:FRAEUI1C_RS27010 ^@ http://purl.uniprot.org/uniprot/E3JAT4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS01600 ^@ http://purl.uniprot.org/uniprot/E3J7D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/298654:FRAEUI1C_RS25435 ^@ http://purl.uniprot.org/uniprot/E3J5M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16900 ^@ http://purl.uniprot.org/uniprot/E3IXV5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS28060 ^@ http://purl.uniprot.org/uniprot/E3IUE5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/298654:FRAEUI1C_RS12920 ^@ http://purl.uniprot.org/uniprot/E3J3Z3 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS20350 ^@ http://purl.uniprot.org/uniprot/E3J983 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS27970 ^@ http://purl.uniprot.org/uniprot/E3JDH9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS22050 ^@ http://purl.uniprot.org/uniprot/E3IUA0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23375 ^@ http://purl.uniprot.org/uniprot/E3IZD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19940 ^@ http://purl.uniprot.org/uniprot/E3J7X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35490 ^@ http://purl.uniprot.org/uniprot/E3IYP6 ^@ Function|||Similarity ^@ Belongs to the EgtB family.|||Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/298654:FRAEUI1C_RS14725 ^@ http://purl.uniprot.org/uniprot/E3JAD2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/298654:FRAEUI1C_RS02705 ^@ http://purl.uniprot.org/uniprot/E3JB95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/298654:FRAEUI1C_RS22855 ^@ http://purl.uniprot.org/uniprot/E3IWX9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/298654:FRAEUI1C_RS23200 ^@ http://purl.uniprot.org/uniprot/E3IY73 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/298654:FRAEUI1C_RS05565 ^@ http://purl.uniprot.org/uniprot/E3J047 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/298654:FRAEUI1C_RS33055 ^@ http://purl.uniprot.org/uniprot/E3JB03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. EgtD family.|||Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS00335 ^@ http://purl.uniprot.org/uniprot/E3J3F3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/298654:FRAEUI1C_RS04690 ^@ http://purl.uniprot.org/uniprot/E3IXJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/298654:FRAEUI1C_RS01140 ^@ http://purl.uniprot.org/uniprot/E3J623 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS00190 ^@ http://purl.uniprot.org/uniprot/E3J287 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/298654:FRAEUI1C_RS32885 ^@ http://purl.uniprot.org/uniprot/E3J9T6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS11600 ^@ http://purl.uniprot.org/uniprot/E3J085 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS36095 ^@ http://purl.uniprot.org/uniprot/E3IWI0 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/298654:FRAEUI1C_RS32310 ^@ http://purl.uniprot.org/uniprot/E3J8E6 ^@ Similarity ^@ Belongs to the gas vesicle GvpA family. http://togogenome.org/gene/298654:FRAEUI1C_RS08940 ^@ http://purl.uniprot.org/uniprot/E3JBI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS04920 ^@ http://purl.uniprot.org/uniprot/E3IYR8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS32430 ^@ http://purl.uniprot.org/uniprot/E3J8H0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05150 ^@ http://purl.uniprot.org/uniprot/E3IYW2 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS40525 ^@ http://purl.uniprot.org/uniprot/E3J8G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS23735 ^@ http://purl.uniprot.org/uniprot/E3IZK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS02175 ^@ http://purl.uniprot.org/uniprot/E3J9V6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS29775 ^@ http://purl.uniprot.org/uniprot/E3IZQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/298654:FRAEUI1C_RS31165 ^@ http://purl.uniprot.org/uniprot/E3J4I8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS32425 ^@ http://purl.uniprot.org/uniprot/E3J8G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS32635 ^@ http://purl.uniprot.org/uniprot/E3J9N9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08335 ^@ http://purl.uniprot.org/uniprot/E3JA37 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS00330 ^@ http://purl.uniprot.org/uniprot/E3J3F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05375 ^@ http://purl.uniprot.org/uniprot/E3J007 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/298654:FRAEUI1C_RS08390 ^@ http://purl.uniprot.org/uniprot/E3JA49 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS31695 ^@ http://purl.uniprot.org/uniprot/E3J5X5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/298654:FRAEUI1C_RS35545 ^@ http://purl.uniprot.org/uniprot/E3IZT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/298654:FRAEUI1C_RS30355 ^@ http://purl.uniprot.org/uniprot/E3J1Y7 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/298654:FRAEUI1C_RS34895 ^@ http://purl.uniprot.org/uniprot/E3IXA1 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11435 ^@ http://purl.uniprot.org/uniprot/E3IZ55 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/298654:FRAEUI1C_RS24205 ^@ http://purl.uniprot.org/uniprot/E3J1R0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/298654:FRAEUI1C_RS26330 ^@ http://purl.uniprot.org/uniprot/E3J894 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS24865 ^@ http://purl.uniprot.org/uniprot/E3J349 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29950 ^@ http://purl.uniprot.org/uniprot/E3J0U8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS16955 ^@ http://purl.uniprot.org/uniprot/E3IXW6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS00015 ^@ http://purl.uniprot.org/uniprot/E3J252 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/298654:FRAEUI1C_RS01645 ^@ http://purl.uniprot.org/uniprot/E3J7E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS09110 ^@ http://purl.uniprot.org/uniprot/E3JCP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS06815 ^@ http://purl.uniprot.org/uniprot/E3J4Y2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS05870 ^@ http://purl.uniprot.org/uniprot/E3J167 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS05380 ^@ http://purl.uniprot.org/uniprot/E3J008 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/298654:FRAEUI1C_RS25070 ^@ http://purl.uniprot.org/uniprot/E3J4C2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11855 ^@ http://purl.uniprot.org/uniprot/E3J197 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/298654:FRAEUI1C_RS33830 ^@ http://purl.uniprot.org/uniprot/E3JDL7 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/298654:FRAEUI1C_RS03140 ^@ http://purl.uniprot.org/uniprot/E3JCL3 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS22195 ^@ http://purl.uniprot.org/uniprot/E3IUC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS31210 ^@ http://purl.uniprot.org/uniprot/E3J4J7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/298654:FRAEUI1C_RS24940 ^@ http://purl.uniprot.org/uniprot/E3J495 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08410 ^@ http://purl.uniprot.org/uniprot/E3JA53 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/298654:FRAEUI1C_RS12375 ^@ http://purl.uniprot.org/uniprot/E3J2K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/298654:FRAEUI1C_RS04650 ^@ http://purl.uniprot.org/uniprot/E3IXI5 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/298654:FRAEUI1C_RS40535 ^@ http://purl.uniprot.org/uniprot/E3J8G7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS24620 ^@ http://purl.uniprot.org/uniprot/E3J2Z9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS19070 ^@ http://purl.uniprot.org/uniprot/E3J470 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS33795 ^@ http://purl.uniprot.org/uniprot/E3JDK9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS05595 ^@ http://purl.uniprot.org/uniprot/E3J053 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS31225 ^@ http://purl.uniprot.org/uniprot/E3J4K0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS02000 ^@ http://purl.uniprot.org/uniprot/E3J8P1 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/298654:FRAEUI1C_RS18160 ^@ http://purl.uniprot.org/uniprot/E3J1J8 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family.|||Belongs to the fatty acyl-CoA reductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27595 ^@ http://purl.uniprot.org/uniprot/E3JC83 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS35205 ^@ http://purl.uniprot.org/uniprot/E3IYI9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27610 ^@ http://purl.uniprot.org/uniprot/E3JC86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08760 ^@ http://purl.uniprot.org/uniprot/E3JBE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS08340 ^@ http://purl.uniprot.org/uniprot/E3JA38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS33705 ^@ http://purl.uniprot.org/uniprot/E3JDJ1 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/298654:FRAEUI1C_RS12225 ^@ http://purl.uniprot.org/uniprot/E3J1G8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35200 ^@ http://purl.uniprot.org/uniprot/E3IYI8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/298654:FRAEUI1C_RS29880 ^@ http://purl.uniprot.org/uniprot/E3IZT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/298654:FRAEUI1C_RS31460 ^@ http://purl.uniprot.org/uniprot/E3J5S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/298654:FRAEUI1C_RS24725 ^@ http://purl.uniprot.org/uniprot/E3J320 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS26125 ^@ http://purl.uniprot.org/uniprot/E3J853 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12405 ^@ http://purl.uniprot.org/uniprot/E3J2L1 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31280 ^@ http://purl.uniprot.org/uniprot/E3J4L1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/298654:FRAEUI1C_RS26515 ^@ http://purl.uniprot.org/uniprot/E3J9G0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17185 ^@ http://purl.uniprot.org/uniprot/E3IY12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS27005 ^@ http://purl.uniprot.org/uniprot/E3JAT3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS35370 ^@ http://purl.uniprot.org/uniprot/E3IYM2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS30935 ^@ http://purl.uniprot.org/uniprot/E3J3B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/298654:FRAEUI1C_RS30665 ^@ http://purl.uniprot.org/uniprot/E3J249 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/298654:FRAEUI1C_RS13065 ^@ http://purl.uniprot.org/uniprot/E3J557 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS12775 ^@ http://purl.uniprot.org/uniprot/E3J3W5 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS33815 ^@ http://purl.uniprot.org/uniprot/E3JDL4 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS18305 ^@ http://purl.uniprot.org/uniprot/E3J1M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS00400 ^@ http://purl.uniprot.org/uniprot/E3J3G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/298654:FRAEUI1C_RS13470 ^@ http://purl.uniprot.org/uniprot/E3J6F7 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/298654:FRAEUI1C_RS18715 ^@ http://purl.uniprot.org/uniprot/E3J2W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS17010 ^@ http://purl.uniprot.org/uniprot/E3IXX7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS05360 ^@ http://purl.uniprot.org/uniprot/E3J004 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/298654:FRAEUI1C_RS11580 ^@ http://purl.uniprot.org/uniprot/E3J081 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/298654:FRAEUI1C_RS03650 ^@ http://purl.uniprot.org/uniprot/E3ITQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/298654:FRAEUI1C_RS30730 ^@ http://purl.uniprot.org/uniprot/E3J371 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/298654:FRAEUI1C_RS16500 ^@ http://purl.uniprot.org/uniprot/E3IWK1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS29675 ^@ http://purl.uniprot.org/uniprot/E3IZN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28035 ^@ http://purl.uniprot.org/uniprot/E3IUE0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/298654:FRAEUI1C_RS23380 ^@ http://purl.uniprot.org/uniprot/E3IZD6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/298654:FRAEUI1C_RS12585 ^@ http://purl.uniprot.org/uniprot/E3J2P6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS09980 ^@ http://purl.uniprot.org/uniprot/E3IV33 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/298654:FRAEUI1C_RS17220 ^@ http://purl.uniprot.org/uniprot/E3IY19 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/298654:FRAEUI1C_RS28585 ^@ http://purl.uniprot.org/uniprot/E3IVT3 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS26235 ^@ http://purl.uniprot.org/uniprot/E3J875 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17135 ^@ http://purl.uniprot.org/uniprot/E3IY02 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS29700 ^@ http://purl.uniprot.org/uniprot/E3IZP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/298654:FRAEUI1C_RS08355 ^@ http://purl.uniprot.org/uniprot/E3JA41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/298654:FRAEUI1C_RS04570 ^@ http://purl.uniprot.org/uniprot/E3IXH2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/298654:FRAEUI1C_RS11785 ^@ http://purl.uniprot.org/uniprot/E3J0C1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/298654:FRAEUI1C_RS31180 ^@ http://purl.uniprot.org/uniprot/E3J4J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/298654:FRAEUI1C_RS12430 ^@ http://purl.uniprot.org/uniprot/E3J2L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS29185 ^@ http://purl.uniprot.org/uniprot/E3IYB4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/298654:FRAEUI1C_RS29985 ^@ http://purl.uniprot.org/uniprot/E3J0V5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS08600 ^@ http://purl.uniprot.org/uniprot/E3JA86 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/298654:FRAEUI1C_RS26605 ^@ http://purl.uniprot.org/uniprot/E3J9H8 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS11860 ^@ http://purl.uniprot.org/uniprot/E3J198 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/298654:FRAEUI1C_RS05020 ^@ http://purl.uniprot.org/uniprot/E3IYT6 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27185 ^@ http://purl.uniprot.org/uniprot/E3JAW9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS07305 ^@ http://purl.uniprot.org/uniprot/E3J6A2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS18485 ^@ http://purl.uniprot.org/uniprot/E3J2S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS28695 ^@ http://purl.uniprot.org/uniprot/E3IVV6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS27730 ^@ http://purl.uniprot.org/uniprot/E3JDD2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/298654:FRAEUI1C_RS06805 ^@ http://purl.uniprot.org/uniprot/E3J4Y0 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/298654:FRAEUI1C_RS15125 ^@ http://purl.uniprot.org/uniprot/E3JBP2 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS31430 ^@ http://purl.uniprot.org/uniprot/E3J4N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/298654:FRAEUI1C_RS08805 ^@ http://purl.uniprot.org/uniprot/E3JBF5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/298654:FRAEUI1C_RS09315 ^@ http://purl.uniprot.org/uniprot/E3JCT5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/298654:FRAEUI1C_RS19455 ^@ http://purl.uniprot.org/uniprot/E3J5I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS13590 ^@ http://purl.uniprot.org/uniprot/E3J6I3 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/298654:FRAEUI1C_RS00995 ^@ http://purl.uniprot.org/uniprot/E3J4W5 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS03835 ^@ http://purl.uniprot.org/uniprot/E3IUW3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/298654:FRAEUI1C_RS26795 ^@ http://purl.uniprot.org/uniprot/E3J9L5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS17450 ^@ http://purl.uniprot.org/uniprot/E3IZ93 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes. http://togogenome.org/gene/298654:FRAEUI1C_RS22940 ^@ http://purl.uniprot.org/uniprot/E3IWZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/298654:FRAEUI1C_RS14150 ^@ http://purl.uniprot.org/uniprot/E3J7W8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/298654:FRAEUI1C_RS14650 ^@ http://purl.uniprot.org/uniprot/E3JAB7 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/298654:FRAEUI1C_RS34155 ^@ http://purl.uniprot.org/uniprot/E3IUN5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/298654:FRAEUI1C_RS13565 ^@ http://purl.uniprot.org/uniprot/E3J6H8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/298654:FRAEUI1C_RS21485 ^@ http://purl.uniprot.org/uniprot/E3JD44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS10075 ^@ http://purl.uniprot.org/uniprot/E3IV52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS35070 ^@ http://purl.uniprot.org/uniprot/E3IXD3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/298654:FRAEUI1C_RS08875 ^@ http://purl.uniprot.org/uniprot/E3JBG9 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/298654:FRAEUI1C_RS18565 ^@ http://purl.uniprot.org/uniprot/E3J2T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/298654:FRAEUI1C_RS03475 ^@ http://purl.uniprot.org/uniprot/E3ITL5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/298654:FRAEUI1C_RS30130 ^@ http://purl.uniprot.org/uniprot/E3J0Y4 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family. http://togogenome.org/gene/298654:FRAEUI1C_RS22820 ^@ http://purl.uniprot.org/uniprot/E3IWX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/298654:FRAEUI1C_RS37500 ^@ http://purl.uniprot.org/uniprot/E3ITX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/298654:FRAEUI1C_RS26445 ^@ http://purl.uniprot.org/uniprot/E3J8B7 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/298654:FRAEUI1C_RS34755 ^@ http://purl.uniprot.org/uniprot/E3IW43 ^@ Function ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.