http://togogenome.org/gene/314260:PB2503_RS07190 ^@ http://purl.uniprot.org/uniprot/E0TGI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/314260:PB2503_RS12605 ^@ http://purl.uniprot.org/uniprot/E0TGQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/314260:PB2503_RS03865 ^@ http://purl.uniprot.org/uniprot/E0TEQ8 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/314260:PB2503_RS12795 ^@ http://purl.uniprot.org/uniprot/E0TGU7 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/314260:PB2503_RS00275 ^@ http://purl.uniprot.org/uniprot/E0TB26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/314260:PB2503_RS12210 ^@ http://purl.uniprot.org/uniprot/E0TFM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02185 ^@ http://purl.uniprot.org/uniprot/E0TCL8 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/314260:PB2503_RS10610 ^@ http://purl.uniprot.org/uniprot/E0TIG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS09690 ^@ http://purl.uniprot.org/uniprot/E0TFY3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/314260:PB2503_RS10485 ^@ http://purl.uniprot.org/uniprot/E0THW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS06395 ^@ http://purl.uniprot.org/uniprot/E0TE70 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/314260:PB2503_RS12340 ^@ http://purl.uniprot.org/uniprot/E0TG41 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS06610 ^@ http://purl.uniprot.org/uniprot/E0TEB3 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/314260:PB2503_RS08880 ^@ http://purl.uniprot.org/uniprot/E0TDB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/314260:PB2503_RS06560 ^@ http://purl.uniprot.org/uniprot/E0TEA3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/314260:PB2503_RS04480 ^@ http://purl.uniprot.org/uniprot/E0TFQ1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS00575 ^@ http://purl.uniprot.org/uniprot/E0TB92 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS00770 ^@ http://purl.uniprot.org/uniprot/E0TBC9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS07815 ^@ http://purl.uniprot.org/uniprot/E0TID8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/314260:PB2503_RS01120 ^@ http://purl.uniprot.org/uniprot/E0TBM2 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS10055 ^@ http://purl.uniprot.org/uniprot/E0TGP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/314260:PB2503_RS02830 ^@ http://purl.uniprot.org/uniprot/E0TDH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS03400 ^@ http://purl.uniprot.org/uniprot/E0TE28 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/314260:PB2503_RS09530 ^@ http://purl.uniprot.org/uniprot/E0TEX6 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/314260:PB2503_RS07740 ^@ http://purl.uniprot.org/uniprot/E0TIC2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/314260:PB2503_RS10470 ^@ http://purl.uniprot.org/uniprot/E0THW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/314260:PB2503_RS06805 ^@ http://purl.uniprot.org/uniprot/E0TEV5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/314260:PB2503_RS03970 ^@ http://purl.uniprot.org/uniprot/E0TES9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/314260:PB2503_RS12725 ^@ http://purl.uniprot.org/uniprot/E0TGT3 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/314260:PB2503_RS13765 ^@ http://purl.uniprot.org/uniprot/E0TEK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/314260:PB2503_RS10480 ^@ http://purl.uniprot.org/uniprot/E0THW4 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/314260:PB2503_RS10415 ^@ http://purl.uniprot.org/uniprot/E0THV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/314260:PB2503_RS04745 ^@ http://purl.uniprot.org/uniprot/E0TFV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/314260:PB2503_RS08630 ^@ http://purl.uniprot.org/uniprot/E0TCU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS00305 ^@ http://purl.uniprot.org/uniprot/E0TB32 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/314260:PB2503_RS01480 ^@ http://purl.uniprot.org/uniprot/E0TBX5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/314260:PB2503_RS02170 ^@ http://purl.uniprot.org/uniprot/E0TCL5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/314260:PB2503_RS10670 ^@ http://purl.uniprot.org/uniprot/E0TC38 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS13490 ^@ http://purl.uniprot.org/uniprot/E0TIJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/314260:PB2503_RS02635 ^@ http://purl.uniprot.org/uniprot/E0TD38 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/314260:PB2503_RS05710 ^@ http://purl.uniprot.org/uniprot/E0THL4 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/314260:PB2503_RS10075 ^@ http://purl.uniprot.org/uniprot/E0TH88 ^@ Cofactor ^@ Binds 1 heme c group covalently per subunit. http://togogenome.org/gene/314260:PB2503_RS02505 ^@ http://purl.uniprot.org/uniprot/E0TD12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/314260:PB2503_RS11125 ^@ http://purl.uniprot.org/uniprot/E0TDF5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/314260:PB2503_RS05375 ^@ http://purl.uniprot.org/uniprot/E0TGZ8 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/314260:PB2503_RS06215 ^@ http://purl.uniprot.org/uniprot/E0TI70 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/314260:PB2503_RS11435 ^@ http://purl.uniprot.org/uniprot/E0TEH0 ^@ Similarity ^@ Belongs to the transglycosylase Slt family.|||Belongs to the virb1 family. http://togogenome.org/gene/314260:PB2503_RS00360 ^@ http://purl.uniprot.org/uniprot/E0TB43 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS02540 ^@ http://purl.uniprot.org/uniprot/E0TD19 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/314260:PB2503_RS07610 ^@ http://purl.uniprot.org/uniprot/E0THS3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/314260:PB2503_RS01475 ^@ http://purl.uniprot.org/uniprot/E0TBX4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/314260:PB2503_RS09005 ^@ http://purl.uniprot.org/uniprot/E0TDD9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS06230 ^@ http://purl.uniprot.org/uniprot/E0TI73 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/314260:PB2503_RS00345 ^@ http://purl.uniprot.org/uniprot/E0TB40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/314260:PB2503_RS12565 ^@ http://purl.uniprot.org/uniprot/E0TGQ0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/314260:PB2503_RS10080 ^@ http://purl.uniprot.org/uniprot/E0TH89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/314260:PB2503_RS13230 ^@ http://purl.uniprot.org/uniprot/E0THZ0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS12780 ^@ http://purl.uniprot.org/uniprot/E0TGU4 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/314260:PB2503_RS01680 ^@ http://purl.uniprot.org/uniprot/E0TC74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04770 ^@ http://purl.uniprot.org/uniprot/E0TG82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS06820 ^@ http://purl.uniprot.org/uniprot/E0TFC9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS02705 ^@ http://purl.uniprot.org/uniprot/E0TD51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01490 ^@ http://purl.uniprot.org/uniprot/E0TBX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/314260:PB2503_RS00490 ^@ http://purl.uniprot.org/uniprot/E0TB75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS10845 ^@ http://purl.uniprot.org/uniprot/E0TCH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS00675 ^@ http://purl.uniprot.org/uniprot/E0TBB0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/314260:PB2503_RS00370 ^@ http://purl.uniprot.org/uniprot/E0TB45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family. Hemolysin C subfamily.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12640 ^@ http://purl.uniprot.org/uniprot/E0TGR6 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/314260:PB2503_RS05120 ^@ http://purl.uniprot.org/uniprot/E0TGF0 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/314260:PB2503_RS03470 ^@ http://purl.uniprot.org/uniprot/E0TE42 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/314260:PB2503_RS04905 ^@ http://purl.uniprot.org/uniprot/E0TGA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS00265 ^@ http://purl.uniprot.org/uniprot/E0TB24 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS05965 ^@ http://purl.uniprot.org/uniprot/E0THR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS07320 ^@ http://purl.uniprot.org/uniprot/E0TGK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||Periplasm|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/314260:PB2503_RS00870 ^@ http://purl.uniprot.org/uniprot/E0TBH5 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/314260:PB2503_RS12690 ^@ http://purl.uniprot.org/uniprot/E0TGS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/314260:PB2503_RS13140 ^@ http://purl.uniprot.org/uniprot/E0THW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08115 ^@ http://purl.uniprot.org/uniprot/E0TBR0 ^@ Similarity ^@ Belongs to the GSP N family. http://togogenome.org/gene/314260:PB2503_RS02860 ^@ http://purl.uniprot.org/uniprot/E0TDI4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/314260:PB2503_RS03065 ^@ http://purl.uniprot.org/uniprot/E0TDM5 ^@ Similarity ^@ Belongs to the argonaute family. Long pAgo subfamily. http://togogenome.org/gene/314260:PB2503_RS11485 ^@ http://purl.uniprot.org/uniprot/E0TEI0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/314260:PB2503_RS03130 ^@ http://purl.uniprot.org/uniprot/E0TDN8 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/314260:PB2503_RS01920 ^@ http://purl.uniprot.org/uniprot/E0TCC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/314260:PB2503_RS08125 ^@ http://purl.uniprot.org/uniprot/E0TBR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01640 ^@ http://purl.uniprot.org/uniprot/E0TC66 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/314260:PB2503_RS12625 ^@ http://purl.uniprot.org/uniprot/E0TGR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02920 ^@ http://purl.uniprot.org/uniprot/E0TDJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS07665 ^@ http://purl.uniprot.org/uniprot/E0TIA7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/314260:PB2503_RS03250 ^@ http://purl.uniprot.org/uniprot/E0TDZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS06165 ^@ http://purl.uniprot.org/uniprot/E0TI59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell inner membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/314260:PB2503_RS01155 ^@ http://purl.uniprot.org/uniprot/E0TBM9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/314260:PB2503_RS04590 ^@ http://purl.uniprot.org/uniprot/E0TFS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS11390 ^@ http://purl.uniprot.org/uniprot/E0TDY4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/314260:PB2503_RS06085 ^@ http://purl.uniprot.org/uniprot/E0TI43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS10550 ^@ http://purl.uniprot.org/uniprot/E0TIF2 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/314260:PB2503_RS10815 ^@ http://purl.uniprot.org/uniprot/E0TCG8 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/314260:PB2503_RS04705 ^@ http://purl.uniprot.org/uniprot/E0TFU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/314260:PB2503_RS11220 ^@ http://purl.uniprot.org/uniprot/E0TDV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/314260:PB2503_RS09190 ^@ http://purl.uniprot.org/uniprot/E0TDT4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS02650 ^@ http://purl.uniprot.org/uniprot/E0TD41 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/314260:PB2503_RS08985 ^@ http://purl.uniprot.org/uniprot/E0TDD5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/314260:PB2503_RS05825 ^@ http://purl.uniprot.org/uniprot/E0THN6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS08850 ^@ http://purl.uniprot.org/uniprot/E0TDA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/314260:PB2503_RS08590 ^@ http://purl.uniprot.org/uniprot/E0TCU1 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/314260:PB2503_RS06355 ^@ http://purl.uniprot.org/uniprot/E0TI98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09050 ^@ http://purl.uniprot.org/uniprot/E0TDQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS11380 ^@ http://purl.uniprot.org/uniprot/E0TDY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS11750 ^@ http://purl.uniprot.org/uniprot/E0TF20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS06180 ^@ http://purl.uniprot.org/uniprot/E0TI63 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Multidrug efflux pump. http://togogenome.org/gene/314260:PB2503_RS04060 ^@ http://purl.uniprot.org/uniprot/E0TF62 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/314260:PB2503_RS04425 ^@ http://purl.uniprot.org/uniprot/E0TFP0 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/314260:PB2503_RS09210 ^@ http://purl.uniprot.org/uniprot/E0TDT8 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/314260:PB2503_RS03365 ^@ http://purl.uniprot.org/uniprot/E0TE21 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/314260:PB2503_RS08895 ^@ http://purl.uniprot.org/uniprot/E0TDB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS05990 ^@ http://purl.uniprot.org/uniprot/E0TI24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS12035 ^@ http://purl.uniprot.org/uniprot/E0TFK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS11020 ^@ http://purl.uniprot.org/uniprot/E0TCX8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/314260:PB2503_RS09655 ^@ http://purl.uniprot.org/uniprot/E0TFH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02095 ^@ http://purl.uniprot.org/uniprot/E0TCK0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS10320 ^@ http://purl.uniprot.org/uniprot/E0THT4 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/314260:PB2503_RS12200 ^@ http://purl.uniprot.org/uniprot/E0TFM5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/314260:PB2503_RS10325 ^@ http://purl.uniprot.org/uniprot/E0THT5 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/314260:PB2503_RS06635 ^@ http://purl.uniprot.org/uniprot/E0TEB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/314260:PB2503_RS05245 ^@ http://purl.uniprot.org/uniprot/E0TGX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09945 ^@ http://purl.uniprot.org/uniprot/E0TGM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09505 ^@ http://purl.uniprot.org/uniprot/E0TEX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/314260:PB2503_RS05275 ^@ http://purl.uniprot.org/uniprot/E0TGY3 ^@ Similarity ^@ Belongs to the argonaute family. Long pAgo subfamily. http://togogenome.org/gene/314260:PB2503_RS02780 ^@ http://purl.uniprot.org/uniprot/E0TD65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08780 ^@ http://purl.uniprot.org/uniprot/E0TD94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS04315 ^@ http://purl.uniprot.org/uniprot/E0TFB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS05800 ^@ http://purl.uniprot.org/uniprot/E0THN1 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/314260:PB2503_RS00580 ^@ http://purl.uniprot.org/uniprot/E0TB93 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/314260:PB2503_RS11300 ^@ http://purl.uniprot.org/uniprot/E0TDW7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/314260:PB2503_RS00915 ^@ http://purl.uniprot.org/uniprot/E0TBI4 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/314260:PB2503_RS05915 ^@ http://purl.uniprot.org/uniprot/E0THQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/314260:PB2503_RS04370 ^@ http://purl.uniprot.org/uniprot/E0TFC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS05785 ^@ http://purl.uniprot.org/uniprot/E0THM8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS05230 ^@ http://purl.uniprot.org/uniprot/E0TGX4 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/314260:PB2503_RS01445 ^@ http://purl.uniprot.org/uniprot/E0TBW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS03710 ^@ http://purl.uniprot.org/uniprot/E0TEM8 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/314260:PB2503_RS04980 ^@ http://purl.uniprot.org/uniprot/E0TGC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS12630 ^@ http://purl.uniprot.org/uniprot/E0TGR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/314260:PB2503_RS10930 ^@ http://purl.uniprot.org/uniprot/E0TCW0 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/314260:PB2503_RS04850 ^@ http://purl.uniprot.org/uniprot/E0TG98 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/314260:PB2503_RS09610 ^@ http://purl.uniprot.org/uniprot/E0TFG2 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/314260:PB2503_RS05215 ^@ http://purl.uniprot.org/uniprot/E0TGX1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/314260:PB2503_RS04265 ^@ http://purl.uniprot.org/uniprot/E0TFA4 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/314260:PB2503_RS03990 ^@ http://purl.uniprot.org/uniprot/E0TF48 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/314260:PB2503_RS09355 ^@ http://purl.uniprot.org/uniprot/E0TEE7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/314260:PB2503_RS13225 ^@ http://purl.uniprot.org/uniprot/E0THY9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/314260:PB2503_RS11070 ^@ http://purl.uniprot.org/uniprot/E0TCY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsuA/YedE (TC 9.B.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS00635 ^@ http://purl.uniprot.org/uniprot/E0TBA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/314260:PB2503_RS03715 ^@ http://purl.uniprot.org/uniprot/E0TEM9 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/314260:PB2503_RS01690 ^@ http://purl.uniprot.org/uniprot/E0TC76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02375 ^@ http://purl.uniprot.org/uniprot/E0TCQ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/314260:PB2503_RS02965 ^@ http://purl.uniprot.org/uniprot/E0TDK5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS13595 ^@ http://purl.uniprot.org/uniprot/E0TB34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02105 ^@ http://purl.uniprot.org/uniprot/E0TCK2 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/314260:PB2503_RS09385 ^@ http://purl.uniprot.org/uniprot/E0TEF3 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/314260:PB2503_RS03835 ^@ http://purl.uniprot.org/uniprot/E0TEQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/314260:PB2503_RS02815 ^@ http://purl.uniprot.org/uniprot/E0TDH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS07090 ^@ http://purl.uniprot.org/uniprot/E0TGG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS11815 ^@ http://purl.uniprot.org/uniprot/E0TF33 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/314260:PB2503_RS05875 ^@ http://purl.uniprot.org/uniprot/E0THP6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS11235 ^@ http://purl.uniprot.org/uniprot/E0TDV3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS02165 ^@ http://purl.uniprot.org/uniprot/E0TCL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/314260:PB2503_RS12890 ^@ http://purl.uniprot.org/uniprot/E0THD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS00375 ^@ http://purl.uniprot.org/uniprot/E0TB46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/314260:PB2503_RS05795 ^@ http://purl.uniprot.org/uniprot/E0THN0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/314260:PB2503_RS07370 ^@ http://purl.uniprot.org/uniprot/E0TH49 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/314260:PB2503_RS12855 ^@ http://purl.uniprot.org/uniprot/E0TGV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10030 ^@ http://purl.uniprot.org/uniprot/E0TGN7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS06050 ^@ http://purl.uniprot.org/uniprot/E0TI36 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/314260:PB2503_RS12730 ^@ http://purl.uniprot.org/uniprot/E0TGT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/314260:PB2503_RS08980 ^@ http://purl.uniprot.org/uniprot/E0TDD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/314260:PB2503_RS08330 ^@ http://purl.uniprot.org/uniprot/E0TC32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/314260:PB2503_RS10995 ^@ http://purl.uniprot.org/uniprot/E0TCX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS12520 ^@ http://purl.uniprot.org/uniprot/E0TG79 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/314260:PB2503_RS07145 ^@ http://purl.uniprot.org/uniprot/E0TGH3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/314260:PB2503_RS09115 ^@ http://purl.uniprot.org/uniprot/E0TDR9 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/314260:PB2503_RS10565 ^@ http://purl.uniprot.org/uniprot/E0TIF5 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/314260:PB2503_RS11410 ^@ http://purl.uniprot.org/uniprot/E0TEG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/314260:PB2503_RS06680 ^@ http://purl.uniprot.org/uniprot/E0TEC7 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/314260:PB2503_RS08430 ^@ http://purl.uniprot.org/uniprot/E0TCF7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS13990 ^@ http://purl.uniprot.org/uniprot/E0TBQ5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GSP I family.|||Cell inner membrane|||Cleaved by prepilin peptidase.|||Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane|||Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. http://togogenome.org/gene/314260:PB2503_RS06810 ^@ http://purl.uniprot.org/uniprot/E0TEV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS07050 ^@ http://purl.uniprot.org/uniprot/E0TFX4 ^@ Function ^@ Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. http://togogenome.org/gene/314260:PB2503_RS04520 ^@ http://purl.uniprot.org/uniprot/E0TFQ9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/314260:PB2503_RS10060 ^@ http://purl.uniprot.org/uniprot/E0TGP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/314260:PB2503_RS08975 ^@ http://purl.uniprot.org/uniprot/E0TDD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/314260:PB2503_RS01130 ^@ http://purl.uniprot.org/uniprot/E0TBM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/314260:PB2503_RS10015 ^@ http://purl.uniprot.org/uniprot/E0TGN4 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/314260:PB2503_RS10400 ^@ http://purl.uniprot.org/uniprot/E0THU8 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS06730 ^@ http://purl.uniprot.org/uniprot/E0TEU0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS09150 ^@ http://purl.uniprot.org/uniprot/E0TDS6 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS10515 ^@ http://purl.uniprot.org/uniprot/E0TIE5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS01870 ^@ http://purl.uniprot.org/uniprot/E0TCB1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/314260:PB2503_RS04990 ^@ http://purl.uniprot.org/uniprot/E0TGC6 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/314260:PB2503_RS06700 ^@ http://purl.uniprot.org/uniprot/E0TET3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08935 ^@ http://purl.uniprot.org/uniprot/E0TDC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS09620 ^@ http://purl.uniprot.org/uniprot/E0TFG4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS09010 ^@ http://purl.uniprot.org/uniprot/E0TDE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/314260:PB2503_RS09045 ^@ http://purl.uniprot.org/uniprot/E0TDQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/314260:PB2503_RS12790 ^@ http://purl.uniprot.org/uniprot/E0TGU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS11405 ^@ http://purl.uniprot.org/uniprot/E0TEG4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/314260:PB2503_RS05820 ^@ http://purl.uniprot.org/uniprot/E0THN5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS11905 ^@ http://purl.uniprot.org/uniprot/E0TFH8 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/314260:PB2503_RS03445 ^@ http://purl.uniprot.org/uniprot/E0TE37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family.|||Cell outer membrane|||Homodimer.|||Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. http://togogenome.org/gene/314260:PB2503_RS00260 ^@ http://purl.uniprot.org/uniprot/E0TB23 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/314260:PB2503_RS10600 ^@ http://purl.uniprot.org/uniprot/E0TIG3 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/314260:PB2503_RS06250 ^@ http://purl.uniprot.org/uniprot/E0TI77 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/314260:PB2503_RS02510 ^@ http://purl.uniprot.org/uniprot/E0TD13 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/314260:PB2503_RS01520 ^@ http://purl.uniprot.org/uniprot/E0TBY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/314260:PB2503_RS04835 ^@ http://purl.uniprot.org/uniprot/E0TG95 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/314260:PB2503_RS01885 ^@ http://purl.uniprot.org/uniprot/E0TCB4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/314260:PB2503_RS03285 ^@ http://purl.uniprot.org/uniprot/E0TE05 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/314260:PB2503_RS00365 ^@ http://purl.uniprot.org/uniprot/E0TB44 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS12525 ^@ http://purl.uniprot.org/uniprot/E0TG80 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/314260:PB2503_RS07465 ^@ http://purl.uniprot.org/uniprot/E0TH67 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/314260:PB2503_RS03110 ^@ http://purl.uniprot.org/uniprot/E0TDN4 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/314260:PB2503_RS00950 ^@ http://purl.uniprot.org/uniprot/E0TBI9 ^@ Function ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. http://togogenome.org/gene/314260:PB2503_RS10685 ^@ http://purl.uniprot.org/uniprot/E0TC41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS07450 ^@ http://purl.uniprot.org/uniprot/E0TH64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02785 ^@ http://purl.uniprot.org/uniprot/E0TD66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08190 ^@ http://purl.uniprot.org/uniprot/E0TC03 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/314260:PB2503_RS06535 ^@ http://purl.uniprot.org/uniprot/E0TE99 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/314260:PB2503_RS07885 ^@ http://purl.uniprot.org/uniprot/E0TBD9 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/314260:PB2503_RS01095 ^@ http://purl.uniprot.org/uniprot/E0TBL7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/314260:PB2503_RS05745 ^@ http://purl.uniprot.org/uniprot/E0THM1 ^@ Function|||Similarity ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family. http://togogenome.org/gene/314260:PB2503_RS09705 ^@ http://purl.uniprot.org/uniprot/E0TFY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08130 ^@ http://purl.uniprot.org/uniprot/E0TBR3 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/314260:PB2503_RS03780 ^@ http://purl.uniprot.org/uniprot/E0TEP2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/314260:PB2503_RS05030 ^@ http://purl.uniprot.org/uniprot/E0TGD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS00590 ^@ http://purl.uniprot.org/uniprot/E0TB94 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS13110 ^@ http://purl.uniprot.org/uniprot/E0THI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS04015 ^@ http://purl.uniprot.org/uniprot/E0TF53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS14135 ^@ http://purl.uniprot.org/uniprot/E0TEI4 ^@ Caution|||Similarity ^@ Belongs to the NTE family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS03900 ^@ http://purl.uniprot.org/uniprot/E0TER5 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/314260:PB2503_RS09515 ^@ http://purl.uniprot.org/uniprot/E0TEX2 ^@ Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/314260:PB2503_RS08995 ^@ http://purl.uniprot.org/uniprot/E0TDD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS03505 ^@ http://purl.uniprot.org/uniprot/E0TE49 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/314260:PB2503_RS07860 ^@ http://purl.uniprot.org/uniprot/E0TBD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/314260:PB2503_RS09000 ^@ http://purl.uniprot.org/uniprot/E0TDD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/314260:PB2503_RS01655 ^@ http://purl.uniprot.org/uniprot/E0TC69 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/314260:PB2503_RS04665 ^@ http://purl.uniprot.org/uniprot/E0TFT8 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/314260:PB2503_RS00995 ^@ http://purl.uniprot.org/uniprot/E0TBJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/314260:PB2503_RS09780 ^@ http://purl.uniprot.org/uniprot/E0TG03 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/314260:PB2503_RS07745 ^@ http://purl.uniprot.org/uniprot/E0TIC3 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/314260:PB2503_RS02420 ^@ http://purl.uniprot.org/uniprot/E0TCZ5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08905 ^@ http://purl.uniprot.org/uniprot/E0TDB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS07965 ^@ http://purl.uniprot.org/uniprot/E0TBF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS03790 ^@ http://purl.uniprot.org/uniprot/E0TEP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02195 ^@ http://purl.uniprot.org/uniprot/E0TCM0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/314260:PB2503_RS10070 ^@ http://purl.uniprot.org/uniprot/E0TH87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/314260:PB2503_RS01375 ^@ http://purl.uniprot.org/uniprot/E0TBV4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS07845 ^@ http://purl.uniprot.org/uniprot/E0TB53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/314260:PB2503_RS14720 ^@ http://purl.uniprot.org/uniprot/E0TH98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/314260:PB2503_RS12720 ^@ http://purl.uniprot.org/uniprot/E0TGT2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS00330 ^@ http://purl.uniprot.org/uniprot/E0TB37 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/314260:PB2503_RS03500 ^@ http://purl.uniprot.org/uniprot/E0TE48 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-52 and Arg-55) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/314260:PB2503_RS08105 ^@ http://purl.uniprot.org/uniprot/E0TBQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP L family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS00690 ^@ http://purl.uniprot.org/uniprot/E0TBB2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS03395 ^@ http://purl.uniprot.org/uniprot/E0TE27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/314260:PB2503_RS12775 ^@ http://purl.uniprot.org/uniprot/E0TGU3 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/314260:PB2503_RS03330 ^@ http://purl.uniprot.org/uniprot/E0TE14 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/314260:PB2503_RS09340 ^@ http://purl.uniprot.org/uniprot/E0TEE4 ^@ Function ^@ Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/314260:PB2503_RS13960 ^@ http://purl.uniprot.org/uniprot/E0TH58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/314260:PB2503_RS02020 ^@ http://purl.uniprot.org/uniprot/E0TCI5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS04130 ^@ http://purl.uniprot.org/uniprot/E0TF76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/314260:PB2503_RS09015 ^@ http://purl.uniprot.org/uniprot/E0TDE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/314260:PB2503_RS05470 ^@ http://purl.uniprot.org/uniprot/E0TH20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10675 ^@ http://purl.uniprot.org/uniprot/E0TC39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/314260:PB2503_RS03620 ^@ http://purl.uniprot.org/uniprot/E0TEL0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/314260:PB2503_RS02450 ^@ http://purl.uniprot.org/uniprot/E0TD02 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/314260:PB2503_RS04345 ^@ http://purl.uniprot.org/uniprot/E0TFC1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/314260:PB2503_RS08195 ^@ http://purl.uniprot.org/uniprot/E0TC04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS10145 ^@ http://purl.uniprot.org/uniprot/E0THA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS09345 ^@ http://purl.uniprot.org/uniprot/E0TEE5 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/314260:PB2503_RS10300 ^@ http://purl.uniprot.org/uniprot/E0THT0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/314260:PB2503_RS02610 ^@ http://purl.uniprot.org/uniprot/E0TD33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS07185 ^@ http://purl.uniprot.org/uniprot/E0TGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS04400 ^@ http://purl.uniprot.org/uniprot/E0TFN5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Binds 1 Mn(2+) or Fe(2+) ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS09730 ^@ http://purl.uniprot.org/uniprot/E0TFZ2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/314260:PB2503_RS08005 ^@ http://purl.uniprot.org/uniprot/E0TBN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/314260:PB2503_RS09020 ^@ http://purl.uniprot.org/uniprot/E0TDE2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/314260:PB2503_RS05920 ^@ http://purl.uniprot.org/uniprot/E0THQ5 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/314260:PB2503_RS09065 ^@ http://purl.uniprot.org/uniprot/E0TDQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS10575 ^@ http://purl.uniprot.org/uniprot/E0TIF7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02935 ^@ http://purl.uniprot.org/uniprot/E0TDJ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/314260:PB2503_RS12335 ^@ http://purl.uniprot.org/uniprot/E0TG40 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/314260:PB2503_RS05050 ^@ http://purl.uniprot.org/uniprot/E0TGD7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS05815 ^@ http://purl.uniprot.org/uniprot/E0THN4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/314260:PB2503_RS03410 ^@ http://purl.uniprot.org/uniprot/E0TE30 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS09070 ^@ http://purl.uniprot.org/uniprot/E0TDR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/314260:PB2503_RS10615 ^@ http://purl.uniprot.org/uniprot/E0TIG6 ^@ Similarity ^@ Belongs to the OmpW/AlkL family. http://togogenome.org/gene/314260:PB2503_RS12970 ^@ http://purl.uniprot.org/uniprot/E0THF1 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/314260:PB2503_RS12385 ^@ http://purl.uniprot.org/uniprot/E0TG51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS04530 ^@ http://purl.uniprot.org/uniprot/E0TFR2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS12460 ^@ http://purl.uniprot.org/uniprot/E0TG67 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/314260:PB2503_RS12165 ^@ http://purl.uniprot.org/uniprot/E0TFL8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS09185 ^@ http://purl.uniprot.org/uniprot/E0TDT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS02335 ^@ http://purl.uniprot.org/uniprot/E0TCP8 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS06725 ^@ http://purl.uniprot.org/uniprot/E0TET9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/314260:PB2503_RS01755 ^@ http://purl.uniprot.org/uniprot/E0TC89 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/314260:PB2503_RS01365 ^@ http://purl.uniprot.org/uniprot/E0TBV2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/314260:PB2503_RS13240 ^@ http://purl.uniprot.org/uniprot/E0THZ2 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/314260:PB2503_RS02930 ^@ http://purl.uniprot.org/uniprot/E0TDJ8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/314260:PB2503_RS04675 ^@ http://purl.uniprot.org/uniprot/E0TFU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/314260:PB2503_RS13050 ^@ http://purl.uniprot.org/uniprot/E0THG7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/314260:PB2503_RS03660 ^@ http://purl.uniprot.org/uniprot/E0TEL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01350 ^@ http://purl.uniprot.org/uniprot/E0TBU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/314260:PB2503_RS03690 ^@ http://purl.uniprot.org/uniprot/E0TEM4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/314260:PB2503_RS01305 ^@ http://purl.uniprot.org/uniprot/E0TBU0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/314260:PB2503_RS07775 ^@ http://purl.uniprot.org/uniprot/E0TIC9 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/314260:PB2503_RS08275 ^@ http://purl.uniprot.org/uniprot/E0TC21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS10940 ^@ http://purl.uniprot.org/uniprot/E0TCW2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/314260:PB2503_RS11030 ^@ http://purl.uniprot.org/uniprot/E0TCY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01005 ^@ http://purl.uniprot.org/uniprot/E0TBJ9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/314260:PB2503_RS08660 ^@ http://purl.uniprot.org/uniprot/E0TD71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS03915 ^@ http://purl.uniprot.org/uniprot/E0TER8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/314260:PB2503_RS12905 ^@ http://purl.uniprot.org/uniprot/E0THD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS12875 ^@ http://purl.uniprot.org/uniprot/E0THD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS05250 ^@ http://purl.uniprot.org/uniprot/E0TGX8 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/314260:PB2503_RS00520 ^@ http://purl.uniprot.org/uniprot/E0TB81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/314260:PB2503_RS01225 ^@ http://purl.uniprot.org/uniprot/E0TBS5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/314260:PB2503_RS04755 ^@ http://purl.uniprot.org/uniprot/E0TFV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS03775 ^@ http://purl.uniprot.org/uniprot/E0TEP1 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/314260:PB2503_RS00860 ^@ http://purl.uniprot.org/uniprot/E0TBH3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/314260:PB2503_RS09080 ^@ http://purl.uniprot.org/uniprot/E0TDR2 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/314260:PB2503_RS08165 ^@ http://purl.uniprot.org/uniprot/E0TBZ8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS01440 ^@ http://purl.uniprot.org/uniprot/E0TBW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS11140 ^@ http://purl.uniprot.org/uniprot/E0TDF8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/314260:PB2503_RS12235 ^@ http://purl.uniprot.org/uniprot/E0TG21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08890 ^@ http://purl.uniprot.org/uniprot/E0TDB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/314260:PB2503_RS03820 ^@ http://purl.uniprot.org/uniprot/E0TEQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/314260:PB2503_RS07460 ^@ http://purl.uniprot.org/uniprot/E0TH66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS07820 ^@ http://purl.uniprot.org/uniprot/E0TID9 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/314260:PB2503_RS09135 ^@ http://purl.uniprot.org/uniprot/E0TDS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/314260:PB2503_RS07210 ^@ http://purl.uniprot.org/uniprot/E0TGI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS11810 ^@ http://purl.uniprot.org/uniprot/E0TF32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS13865 ^@ http://purl.uniprot.org/uniprot/E0TGZ6 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/314260:PB2503_RS09865 ^@ http://purl.uniprot.org/uniprot/E0TG19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/314260:PB2503_RS05325 ^@ http://purl.uniprot.org/uniprot/E0TGZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02385 ^@ http://purl.uniprot.org/uniprot/E0TCQ8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS07165 ^@ http://purl.uniprot.org/uniprot/E0TGH7 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/314260:PB2503_RS13300 ^@ http://purl.uniprot.org/uniprot/E0TI02 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/314260:PB2503_RS05580 ^@ http://purl.uniprot.org/uniprot/E0THI8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS13000 ^@ http://purl.uniprot.org/uniprot/E0THF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS07880 ^@ http://purl.uniprot.org/uniprot/E0TBD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/314260:PB2503_RS03420 ^@ http://purl.uniprot.org/uniprot/E0TE32 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/314260:PB2503_RS02740 ^@ http://purl.uniprot.org/uniprot/E0TD57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS10810 ^@ http://purl.uniprot.org/uniprot/E0TCG7 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/314260:PB2503_RS06520 ^@ http://purl.uniprot.org/uniprot/E0TE96 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/314260:PB2503_RS09820 ^@ http://purl.uniprot.org/uniprot/E0TG10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurD2 subfamily.|||Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS07335 ^@ http://purl.uniprot.org/uniprot/E0TH43 ^@ Similarity ^@ Belongs to the FliN/MopA/SpaO family. http://togogenome.org/gene/314260:PB2503_RS05240 ^@ http://purl.uniprot.org/uniprot/E0TGX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04440 ^@ http://purl.uniprot.org/uniprot/E0TFP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OpgD/OpgG family.|||Periplasm http://togogenome.org/gene/314260:PB2503_RS00825 ^@ http://purl.uniprot.org/uniprot/E0TBG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/314260:PB2503_RS11260 ^@ http://purl.uniprot.org/uniprot/E0TDV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS03360 ^@ http://purl.uniprot.org/uniprot/E0TE20 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/314260:PB2503_RS12315 ^@ http://purl.uniprot.org/uniprot/E0TG36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04540 ^@ http://purl.uniprot.org/uniprot/E0TFR4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/314260:PB2503_RS13635 ^@ http://purl.uniprot.org/uniprot/E0TBH6 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/314260:PB2503_RS02220 ^@ http://purl.uniprot.org/uniprot/E0TCM5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS10980 ^@ http://purl.uniprot.org/uniprot/E0TCX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/314260:PB2503_RS02190 ^@ http://purl.uniprot.org/uniprot/E0TCL9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/314260:PB2503_RS02275 ^@ http://purl.uniprot.org/uniprot/E0TCN6 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS10110 ^@ http://purl.uniprot.org/uniprot/E0TH94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/314260:PB2503_RS04020 ^@ http://purl.uniprot.org/uniprot/E0TF54 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/314260:PB2503_RS03685 ^@ http://purl.uniprot.org/uniprot/E0TEM3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/314260:PB2503_RS11250 ^@ http://purl.uniprot.org/uniprot/E0TDV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01695 ^@ http://purl.uniprot.org/uniprot/E0TC77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS10885 ^@ http://purl.uniprot.org/uniprot/E0TCH8 ^@ Function ^@ Acts on leucine, isoleucine and valine. http://togogenome.org/gene/314260:PB2503_RS09175 ^@ http://purl.uniprot.org/uniprot/E0TDT1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS04135 ^@ http://purl.uniprot.org/uniprot/E0TF77 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/314260:PB2503_RS08140 ^@ http://purl.uniprot.org/uniprot/E0TBR5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/314260:PB2503_RS03005 ^@ http://purl.uniprot.org/uniprot/E0TDL3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/314260:PB2503_RS03430 ^@ http://purl.uniprot.org/uniprot/E0TE34 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/314260:PB2503_RS08825 ^@ http://purl.uniprot.org/uniprot/E0TDA2 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/314260:PB2503_RS13475 ^@ http://purl.uniprot.org/uniprot/E0TIJ2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS11470 ^@ http://purl.uniprot.org/uniprot/E0TD69 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/314260:PB2503_RS05065 ^@ http://purl.uniprot.org/uniprot/E0TGE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS12475 ^@ http://purl.uniprot.org/uniprot/E0TG70 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/314260:PB2503_RS05700 ^@ http://purl.uniprot.org/uniprot/E0THL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/314260:PB2503_RS14715 ^@ http://purl.uniprot.org/uniprot/E0TG11 ^@ Function|||Similarity ^@ Belongs to the MurL family.|||Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate. http://togogenome.org/gene/314260:PB2503_RS11455 ^@ http://purl.uniprot.org/uniprot/E0TEH4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS04210 ^@ http://purl.uniprot.org/uniprot/E0TF93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/314260:PB2503_RS01465 ^@ http://purl.uniprot.org/uniprot/E0TBX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS01515 ^@ http://purl.uniprot.org/uniprot/E0TBY2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/314260:PB2503_RS11275 ^@ http://purl.uniprot.org/uniprot/E0TDW2 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/314260:PB2503_RS04790 ^@ http://purl.uniprot.org/uniprot/E0TG86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10290 ^@ http://purl.uniprot.org/uniprot/E0THS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS12540 ^@ http://purl.uniprot.org/uniprot/E0TGP5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/314260:PB2503_RS10455 ^@ http://purl.uniprot.org/uniprot/E0THV9 ^@ Similarity ^@ Belongs to the lycopene cyclase family. http://togogenome.org/gene/314260:PB2503_RS04330 ^@ http://purl.uniprot.org/uniprot/E0TFB7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/314260:PB2503_RS05530 ^@ http://purl.uniprot.org/uniprot/E0TH34 ^@ Similarity ^@ Belongs to the argonaute family. Long pAgo subfamily. http://togogenome.org/gene/314260:PB2503_RS12405 ^@ http://purl.uniprot.org/uniprot/E0TG55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12010 ^@ http://purl.uniprot.org/uniprot/E0TFJ7 ^@ Similarity ^@ Belongs to the TrbE/VirB4 family. http://togogenome.org/gene/314260:PB2503_RS07395 ^@ http://purl.uniprot.org/uniprot/E0TH54 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/314260:PB2503_RS04550 ^@ http://purl.uniprot.org/uniprot/E0TFR6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS01545 ^@ http://purl.uniprot.org/uniprot/E0TBY8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS10835 ^@ http://purl.uniprot.org/uniprot/E0TCH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/314260:PB2503_RS09320 ^@ http://purl.uniprot.org/uniprot/E0TEE0 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/314260:PB2503_RS00830 ^@ http://purl.uniprot.org/uniprot/E0TBG8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/314260:PB2503_RS02490 ^@ http://purl.uniprot.org/uniprot/E0TD09 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/314260:PB2503_RS10915 ^@ http://purl.uniprot.org/uniprot/E0TCV7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/314260:PB2503_RS10495 ^@ http://purl.uniprot.org/uniprot/E0TIE1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.|||Binds 1 Co(2+) ion per subunit.|||Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway. http://togogenome.org/gene/314260:PB2503_RS04910 ^@ http://purl.uniprot.org/uniprot/E0TGB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08480 ^@ http://purl.uniprot.org/uniprot/E0TCR9 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/314260:PB2503_RS12950 ^@ http://purl.uniprot.org/uniprot/E0THE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.|||Cell inner membrane|||Forms a complex with DabA.|||Membrane|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/314260:PB2503_RS04940 ^@ http://purl.uniprot.org/uniprot/E0TGB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS03800 ^@ http://purl.uniprot.org/uniprot/E0TEP6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/314260:PB2503_RS12215 ^@ http://purl.uniprot.org/uniprot/E0TFM8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/314260:PB2503_RS11465 ^@ http://purl.uniprot.org/uniprot/E0TEH6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/314260:PB2503_RS04710 ^@ http://purl.uniprot.org/uniprot/E0TFU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/314260:PB2503_RS08290 ^@ http://purl.uniprot.org/uniprot/E0TC24 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/314260:PB2503_RS04055 ^@ http://purl.uniprot.org/uniprot/E0TF61 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/314260:PB2503_RS05670 ^@ http://purl.uniprot.org/uniprot/E0THK5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS00270 ^@ http://purl.uniprot.org/uniprot/E0TB25 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/314260:PB2503_RS08225 ^@ http://purl.uniprot.org/uniprot/E0TC11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/314260:PB2503_RS09435 ^@ http://purl.uniprot.org/uniprot/E0TEG3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/314260:PB2503_RS07075 ^@ http://purl.uniprot.org/uniprot/E0TFX9 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/314260:PB2503_RS04875 ^@ http://purl.uniprot.org/uniprot/E0TGA3 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/314260:PB2503_RS08340 ^@ http://purl.uniprot.org/uniprot/E0TCD7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/314260:PB2503_RS06690 ^@ http://purl.uniprot.org/uniprot/E0TEC9 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS08765 ^@ http://purl.uniprot.org/uniprot/E0TD91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/314260:PB2503_RS12205 ^@ http://purl.uniprot.org/uniprot/E0TFM6 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/314260:PB2503_RS10160 ^@ http://purl.uniprot.org/uniprot/E0THA4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/314260:PB2503_RS08965 ^@ http://purl.uniprot.org/uniprot/E0TDD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/314260:PB2503_RS12265 ^@ http://purl.uniprot.org/uniprot/E0TG26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/314260:PB2503_RS12900 ^@ http://purl.uniprot.org/uniprot/E0THD6 ^@ Similarity ^@ Belongs to the OmpW/AlkL family. http://togogenome.org/gene/314260:PB2503_RS11255 ^@ http://purl.uniprot.org/uniprot/E0TDV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS01990 ^@ http://purl.uniprot.org/uniprot/E0TCD5 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS01880 ^@ http://purl.uniprot.org/uniprot/E0TCB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/314260:PB2503_RS10790 ^@ http://purl.uniprot.org/uniprot/E0TCG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08235 ^@ http://purl.uniprot.org/uniprot/E0TC13 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/314260:PB2503_RS01580 ^@ http://purl.uniprot.org/uniprot/E0TBZ4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/314260:PB2503_RS08145 ^@ http://purl.uniprot.org/uniprot/E0TBR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/314260:PB2503_RS08270 ^@ http://purl.uniprot.org/uniprot/E0TC20 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/314260:PB2503_RS08100 ^@ http://purl.uniprot.org/uniprot/E0TBQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS01795 ^@ http://purl.uniprot.org/uniprot/E0TC97 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/314260:PB2503_RS09510 ^@ http://purl.uniprot.org/uniprot/E0TEX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/314260:PB2503_RS09755 ^@ http://purl.uniprot.org/uniprot/E0TFZ8 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/314260:PB2503_RS09025 ^@ http://purl.uniprot.org/uniprot/E0TDE3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/314260:PB2503_RS08070 ^@ http://purl.uniprot.org/uniprot/E0TBQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.|||Belongs to the GSP E family.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS02270 ^@ http://purl.uniprot.org/uniprot/E0TCN5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS02255 ^@ http://purl.uniprot.org/uniprot/E0TCN2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS00335 ^@ http://purl.uniprot.org/uniprot/E0TB38 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/314260:PB2503_RS02620 ^@ http://purl.uniprot.org/uniprot/E0TD35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/314260:PB2503_RS03270 ^@ http://purl.uniprot.org/uniprot/E0TE02 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/314260:PB2503_RS08160 ^@ http://purl.uniprot.org/uniprot/E0TBR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/314260:PB2503_RS08315 ^@ http://purl.uniprot.org/uniprot/E0TC29 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/314260:PB2503_RS06450 ^@ http://purl.uniprot.org/uniprot/E0TE81 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/314260:PB2503_RS08465 ^@ http://purl.uniprot.org/uniprot/E0TCR5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/314260:PB2503_RS08620 ^@ http://purl.uniprot.org/uniprot/E0TCU7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS02315 ^@ http://purl.uniprot.org/uniprot/E0TCP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS12945 ^@ http://purl.uniprot.org/uniprot/E0THE6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS11855 ^@ http://purl.uniprot.org/uniprot/E0TF42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS08180 ^@ http://purl.uniprot.org/uniprot/E0TC01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/314260:PB2503_RS09880 ^@ http://purl.uniprot.org/uniprot/E0TGK9 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/314260:PB2503_RS00890 ^@ http://purl.uniprot.org/uniprot/E0TBH9 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/314260:PB2503_RS06195 ^@ http://purl.uniprot.org/uniprot/E0TI66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS07640 ^@ http://purl.uniprot.org/uniprot/E0TIA2 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/314260:PB2503_RS03300 ^@ http://purl.uniprot.org/uniprot/E0TE08 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/314260:PB2503_RS13185 ^@ http://purl.uniprot.org/uniprot/E0THX9 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/314260:PB2503_RS03875 ^@ http://purl.uniprot.org/uniprot/E0TER0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/314260:PB2503_RS00470 ^@ http://purl.uniprot.org/uniprot/E0TB71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Could be part of an ABC transporter complex.|||Membrane http://togogenome.org/gene/314260:PB2503_RS01115 ^@ http://purl.uniprot.org/uniprot/E0TBM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10450 ^@ http://purl.uniprot.org/uniprot/E0THV8 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/314260:PB2503_RS00320 ^@ http://purl.uniprot.org/uniprot/E0TB35 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/314260:PB2503_RS05975 ^@ http://purl.uniprot.org/uniprot/E0TI21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS01000 ^@ http://purl.uniprot.org/uniprot/E0TBJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/314260:PB2503_RS09215 ^@ http://purl.uniprot.org/uniprot/E0TDT9 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/314260:PB2503_RS07215 ^@ http://purl.uniprot.org/uniprot/E0TGI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS00340 ^@ http://purl.uniprot.org/uniprot/E0TB39 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/314260:PB2503_RS07970 ^@ http://purl.uniprot.org/uniprot/E0TBF5 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/314260:PB2503_RS12610 ^@ http://purl.uniprot.org/uniprot/E0TGQ9 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/314260:PB2503_RS01535 ^@ http://purl.uniprot.org/uniprot/E0TBY6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/314260:PB2503_RS08770 ^@ http://purl.uniprot.org/uniprot/E0TD92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/314260:PB2503_RS01530 ^@ http://purl.uniprot.org/uniprot/E0TBY5 ^@ Similarity ^@ Belongs to the UPF0262 family. http://togogenome.org/gene/314260:PB2503_RS10895 ^@ http://purl.uniprot.org/uniprot/E0TCI0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS08355 ^@ http://purl.uniprot.org/uniprot/E0TCE0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/314260:PB2503_RS02800 ^@ http://purl.uniprot.org/uniprot/E0TD69 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/314260:PB2503_RS04645 ^@ http://purl.uniprot.org/uniprot/E0TFT4 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/314260:PB2503_RS11335 ^@ http://purl.uniprot.org/uniprot/E0TDX4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/314260:PB2503_RS09875 ^@ http://purl.uniprot.org/uniprot/E0TGK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/314260:PB2503_RS01630 ^@ http://purl.uniprot.org/uniprot/E0TC64 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/314260:PB2503_RS07315 ^@ http://purl.uniprot.org/uniprot/E0TGK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/314260:PB2503_RS13370 ^@ http://purl.uniprot.org/uniprot/E0TI17 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS08920 ^@ http://purl.uniprot.org/uniprot/E0TDC2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/314260:PB2503_RS01915 ^@ http://purl.uniprot.org/uniprot/E0TCC0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/314260:PB2503_RS03595 ^@ http://purl.uniprot.org/uniprot/E0TEK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS02395 ^@ http://purl.uniprot.org/uniprot/E0TCR0 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/314260:PB2503_RS13345 ^@ http://purl.uniprot.org/uniprot/E0TI12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS07850 ^@ http://purl.uniprot.org/uniprot/E0TB54 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/314260:PB2503_RS03605 ^@ http://purl.uniprot.org/uniprot/E0TEK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/314260:PB2503_RS06415 ^@ http://purl.uniprot.org/uniprot/E0TE74 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/314260:PB2503_RS06460 ^@ http://purl.uniprot.org/uniprot/E0TE83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS11995 ^@ http://purl.uniprot.org/uniprot/E0TFJ4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/314260:PB2503_RS12030 ^@ http://purl.uniprot.org/uniprot/E0TFK1 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/314260:PB2503_RS03890 ^@ http://purl.uniprot.org/uniprot/E0TER3 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/314260:PB2503_RS08955 ^@ http://purl.uniprot.org/uniprot/E0TDC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS13075 ^@ http://purl.uniprot.org/uniprot/E0THH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaE family.|||Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/314260:PB2503_RS07030 ^@ http://purl.uniprot.org/uniprot/E0TFX2 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/314260:PB2503_RS09055 ^@ http://purl.uniprot.org/uniprot/E0TDQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12895 ^@ http://purl.uniprot.org/uniprot/E0THD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS01850 ^@ http://purl.uniprot.org/uniprot/E0TCA7 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/314260:PB2503_RS01845 ^@ http://purl.uniprot.org/uniprot/E0TCA6 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/314260:PB2503_RS10355 ^@ http://purl.uniprot.org/uniprot/E0THU0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS08635 ^@ http://purl.uniprot.org/uniprot/E0TCV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS03475 ^@ http://purl.uniprot.org/uniprot/E0TE43 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/314260:PB2503_RS04900 ^@ http://purl.uniprot.org/uniprot/E0TGA8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/314260:PB2503_RS08230 ^@ http://purl.uniprot.org/uniprot/E0TC12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS01740 ^@ http://purl.uniprot.org/uniprot/E0TC86 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/314260:PB2503_RS12870 ^@ http://purl.uniprot.org/uniprot/E0TGW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS07345 ^@ http://purl.uniprot.org/uniprot/E0TH45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10245 ^@ http://purl.uniprot.org/uniprot/E0THC1 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/314260:PB2503_RS03930 ^@ http://purl.uniprot.org/uniprot/E0TES1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/314260:PB2503_RS08695 ^@ http://purl.uniprot.org/uniprot/E0TD77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS08670 ^@ http://purl.uniprot.org/uniprot/E0TD72 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/314260:PB2503_RS08925 ^@ http://purl.uniprot.org/uniprot/E0TDC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/314260:PB2503_RS05890 ^@ http://purl.uniprot.org/uniprot/E0THP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS11205 ^@ http://purl.uniprot.org/uniprot/E0TDH0 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS03310 ^@ http://purl.uniprot.org/uniprot/E0TE10 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/314260:PB2503_RS03385 ^@ http://purl.uniprot.org/uniprot/E0TE25 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/314260:PB2503_RS08110 ^@ http://purl.uniprot.org/uniprot/E0TBQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP M family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS04650 ^@ http://purl.uniprot.org/uniprot/E0TFT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS13265 ^@ http://purl.uniprot.org/uniprot/E0THZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS13485 ^@ http://purl.uniprot.org/uniprot/E0TIJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12635 ^@ http://purl.uniprot.org/uniprot/E0TGR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/314260:PB2503_RS11315 ^@ http://purl.uniprot.org/uniprot/E0TDX0 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/314260:PB2503_RS10965 ^@ http://purl.uniprot.org/uniprot/E0TCW7 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/314260:PB2503_RS01860 ^@ http://purl.uniprot.org/uniprot/E0TCA9 ^@ Similarity ^@ Belongs to the thioredoxin family. DsbE subfamily. http://togogenome.org/gene/314260:PB2503_RS07455 ^@ http://purl.uniprot.org/uniprot/E0TH65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04205 ^@ http://purl.uniprot.org/uniprot/E0TF92 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/314260:PB2503_RS02995 ^@ http://purl.uniprot.org/uniprot/E0TDL1 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/314260:PB2503_RS08845 ^@ http://purl.uniprot.org/uniprot/E0TDA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/314260:PB2503_RS00990 ^@ http://purl.uniprot.org/uniprot/E0TBJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/314260:PB2503_RS01495 ^@ http://purl.uniprot.org/uniprot/E0TBX8 ^@ Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.|||Sulfate-activating enzymes, NodP and NodQ, may be physically associated.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/314260:PB2503_RS01415 ^@ http://purl.uniprot.org/uniprot/E0TBW2 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/314260:PB2503_RS08650 ^@ http://purl.uniprot.org/uniprot/E0TCV3 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS02565 ^@ http://purl.uniprot.org/uniprot/E0TD24 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/314260:PB2503_RS11055 ^@ http://purl.uniprot.org/uniprot/E0TCY5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/314260:PB2503_RS04285 ^@ http://purl.uniprot.org/uniprot/E0TFA8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS02245 ^@ http://purl.uniprot.org/uniprot/E0TCN0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/314260:PB2503_RS10025 ^@ http://purl.uniprot.org/uniprot/E0TGN6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/314260:PB2503_RS13380 ^@ http://purl.uniprot.org/uniprot/E0TI19 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/314260:PB2503_RS10540 ^@ http://purl.uniprot.org/uniprot/E0TIF0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/314260:PB2503_RS07660 ^@ http://purl.uniprot.org/uniprot/E0TIA6 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/314260:PB2503_RS05925 ^@ http://purl.uniprot.org/uniprot/E0THQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/314260:PB2503_RS09155 ^@ http://purl.uniprot.org/uniprot/E0TDS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/314260:PB2503_RS01775 ^@ http://purl.uniprot.org/uniprot/E0TC93 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS07730 ^@ http://purl.uniprot.org/uniprot/E0TIC0 ^@ Similarity ^@ Belongs to the UPF0174 family. http://togogenome.org/gene/314260:PB2503_RS09675 ^@ http://purl.uniprot.org/uniprot/E0TFY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/314260:PB2503_RS08945 ^@ http://purl.uniprot.org/uniprot/E0TDC7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS00515 ^@ http://purl.uniprot.org/uniprot/E0TB80 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/314260:PB2503_RS04760 ^@ http://purl.uniprot.org/uniprot/E0TFV8 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/314260:PB2503_RS01925 ^@ http://purl.uniprot.org/uniprot/E0TCC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/314260:PB2503_RS12020 ^@ http://purl.uniprot.org/uniprot/E0TFJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10420 ^@ http://purl.uniprot.org/uniprot/E0THV2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS02400 ^@ http://purl.uniprot.org/uniprot/E0TCZ1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/314260:PB2503_RS01960 ^@ http://purl.uniprot.org/uniprot/E0TCD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/314260:PB2503_RS02015 ^@ http://purl.uniprot.org/uniprot/E0TCI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/314260:PB2503_RS04050 ^@ http://purl.uniprot.org/uniprot/E0TF60 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/314260:PB2503_RS01040 ^@ http://purl.uniprot.org/uniprot/E0TBK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/314260:PB2503_RS08075 ^@ http://purl.uniprot.org/uniprot/E0TBQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04535 ^@ http://purl.uniprot.org/uniprot/E0TFR3 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/314260:PB2503_RS09790 ^@ http://purl.uniprot.org/uniprot/E0TG05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/314260:PB2503_RS01950 ^@ http://purl.uniprot.org/uniprot/E0TCC8 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/314260:PB2503_RS12415 ^@ http://purl.uniprot.org/uniprot/E0TG57 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/314260:PB2503_RS10045 ^@ http://purl.uniprot.org/uniprot/E0TGP0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS08410 ^@ http://purl.uniprot.org/uniprot/E0TCF2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS07530 ^@ http://purl.uniprot.org/uniprot/E0TH81 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/314260:PB2503_RS10520 ^@ http://purl.uniprot.org/uniprot/E0TIE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS09225 ^@ http://purl.uniprot.org/uniprot/E0TDU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/314260:PB2503_RS03825 ^@ http://purl.uniprot.org/uniprot/E0TEQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/314260:PB2503_RS12395 ^@ http://purl.uniprot.org/uniprot/E0TG53 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/314260:PB2503_RS04230 ^@ http://purl.uniprot.org/uniprot/E0TF97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS11095 ^@ http://purl.uniprot.org/uniprot/E0TDE9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/314260:PB2503_RS06080 ^@ http://purl.uniprot.org/uniprot/E0TI42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS01750 ^@ http://purl.uniprot.org/uniprot/E0TC88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS05045 ^@ http://purl.uniprot.org/uniprot/E0TGD6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/314260:PB2503_RS09465 ^@ http://purl.uniprot.org/uniprot/E0TEW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS10525 ^@ http://purl.uniprot.org/uniprot/E0TIE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS06170 ^@ http://purl.uniprot.org/uniprot/E0TI61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/314260:PB2503_RS05690 ^@ http://purl.uniprot.org/uniprot/E0THL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08435 ^@ http://purl.uniprot.org/uniprot/E0TCF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS04845 ^@ http://purl.uniprot.org/uniprot/E0TG97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/314260:PB2503_RS13480 ^@ http://purl.uniprot.org/uniprot/E0TIJ3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/314260:PB2503_RS03375 ^@ http://purl.uniprot.org/uniprot/E0TE23 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/314260:PB2503_RS02205 ^@ http://purl.uniprot.org/uniprot/E0TCM2 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/314260:PB2503_RS10555 ^@ http://purl.uniprot.org/uniprot/E0TIF3 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/314260:PB2503_RS01315 ^@ http://purl.uniprot.org/uniprot/E0TBU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS03145 ^@ http://purl.uniprot.org/uniprot/E0TDP1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/314260:PB2503_RS13450 ^@ http://purl.uniprot.org/uniprot/E0TII7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04420 ^@ http://purl.uniprot.org/uniprot/E0TFN9 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/314260:PB2503_RS08875 ^@ http://purl.uniprot.org/uniprot/E0TDB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/314260:PB2503_RS00300 ^@ http://purl.uniprot.org/uniprot/E0TB31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/314260:PB2503_RS02590 ^@ http://purl.uniprot.org/uniprot/E0TD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS09600 ^@ http://purl.uniprot.org/uniprot/E0TFG0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/314260:PB2503_RS08600 ^@ http://purl.uniprot.org/uniprot/E0TCU3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/314260:PB2503_RS03295 ^@ http://purl.uniprot.org/uniprot/E0TE07 ^@ Similarity ^@ Belongs to the thioester dehydratase family. FabA subfamily. http://togogenome.org/gene/314260:PB2503_RS04105 ^@ http://purl.uniprot.org/uniprot/E0TF71 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/314260:PB2503_RS13500 ^@ http://purl.uniprot.org/uniprot/E0TIJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS06590 ^@ http://purl.uniprot.org/uniprot/E0TEA9 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/314260:PB2503_RS10635 ^@ http://purl.uniprot.org/uniprot/E0TIH0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/314260:PB2503_RS08970 ^@ http://purl.uniprot.org/uniprot/E0TDD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/314260:PB2503_RS05255 ^@ http://purl.uniprot.org/uniprot/E0TGX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10530 ^@ http://purl.uniprot.org/uniprot/E0TIE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS12960 ^@ http://purl.uniprot.org/uniprot/E0THE9 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/314260:PB2503_RS07795 ^@ http://purl.uniprot.org/uniprot/E0TID4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/314260:PB2503_RS11790 ^@ http://purl.uniprot.org/uniprot/E0TF28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04725 ^@ http://purl.uniprot.org/uniprot/E0TFV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/314260:PB2503_RS07925 ^@ http://purl.uniprot.org/uniprot/E0TBE7 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/314260:PB2503_RS01235 ^@ http://purl.uniprot.org/uniprot/E0TBS7 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/314260:PB2503_RS13180 ^@ http://purl.uniprot.org/uniprot/E0THX8 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/314260:PB2503_RS08575 ^@ http://purl.uniprot.org/uniprot/E0TCT8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Arsenite methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS00410 ^@ http://purl.uniprot.org/uniprot/E0TB58 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/314260:PB2503_RS06315 ^@ http://purl.uniprot.org/uniprot/E0TI90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS06090 ^@ http://purl.uniprot.org/uniprot/E0TI44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/314260:PB2503_RS02820 ^@ http://purl.uniprot.org/uniprot/E0TDH6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/314260:PB2503_RS09260 ^@ http://purl.uniprot.org/uniprot/E0TDU8 ^@ Caution|||Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS09470 ^@ http://purl.uniprot.org/uniprot/E0TEW3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/314260:PB2503_RS03340 ^@ http://purl.uniprot.org/uniprot/E0TE16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS11325 ^@ http://purl.uniprot.org/uniprot/E0TDX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/314260:PB2503_RS13100 ^@ http://purl.uniprot.org/uniprot/E0THH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS07705 ^@ http://purl.uniprot.org/uniprot/E0TIB5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/314260:PB2503_RS00430 ^@ http://purl.uniprot.org/uniprot/E0TB62 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS12925 ^@ http://purl.uniprot.org/uniprot/E0THE1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS09715 ^@ http://purl.uniprot.org/uniprot/E0TFY8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/314260:PB2503_RS02880 ^@ http://purl.uniprot.org/uniprot/E0TDI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/314260:PB2503_RS02260 ^@ http://purl.uniprot.org/uniprot/E0TCN3 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/314260:PB2503_RS11190 ^@ http://purl.uniprot.org/uniprot/E0TDG7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/314260:PB2503_RS02750 ^@ http://purl.uniprot.org/uniprot/E0TD59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02640 ^@ http://purl.uniprot.org/uniprot/E0TD39 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/314260:PB2503_RS12420 ^@ http://purl.uniprot.org/uniprot/E0TG58 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS01770 ^@ http://purl.uniprot.org/uniprot/E0TC92 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/314260:PB2503_RS02030 ^@ http://purl.uniprot.org/uniprot/E0TCI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS02680 ^@ http://purl.uniprot.org/uniprot/E0TD46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS03920 ^@ http://purl.uniprot.org/uniprot/E0TER9 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/314260:PB2503_RS10395 ^@ http://purl.uniprot.org/uniprot/E0THU7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/314260:PB2503_RS08505 ^@ http://purl.uniprot.org/uniprot/E0TCS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10955 ^@ http://purl.uniprot.org/uniprot/E0TCW5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/314260:PB2503_RS02210 ^@ http://purl.uniprot.org/uniprot/E0TCM3 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/314260:PB2503_RS08950 ^@ http://purl.uniprot.org/uniprot/E0TDC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/314260:PB2503_RS13955 ^@ http://purl.uniprot.org/uniprot/E0TH51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/314260:PB2503_RS12115 ^@ http://purl.uniprot.org/uniprot/E0TFK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02445 ^@ http://purl.uniprot.org/uniprot/E0TD01 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/314260:PB2503_RS06670 ^@ http://purl.uniprot.org/uniprot/E0TEC5 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/314260:PB2503_RS09665 ^@ http://purl.uniprot.org/uniprot/E0TFH3 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/314260:PB2503_RS09630 ^@ http://purl.uniprot.org/uniprot/E0TFG7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/314260:PB2503_RS07865 ^@ http://purl.uniprot.org/uniprot/E0TBD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/314260:PB2503_RS08885 ^@ http://purl.uniprot.org/uniprot/E0TDB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS06655 ^@ http://purl.uniprot.org/uniprot/E0TEC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS02390 ^@ http://purl.uniprot.org/uniprot/E0TCQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/314260:PB2503_RS02690 ^@ http://purl.uniprot.org/uniprot/E0TD48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/314260:PB2503_RS07440 ^@ http://purl.uniprot.org/uniprot/E0TH62 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/314260:PB2503_RS03980 ^@ http://purl.uniprot.org/uniprot/E0TET1 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/314260:PB2503_RS06870 ^@ http://purl.uniprot.org/uniprot/E0TFD9 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS02895 ^@ http://purl.uniprot.org/uniprot/E0TDJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/314260:PB2503_RS02200 ^@ http://purl.uniprot.org/uniprot/E0TCM1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/314260:PB2503_RS10140 ^@ http://purl.uniprot.org/uniprot/E0THA0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 7 family. http://togogenome.org/gene/314260:PB2503_RS03720 ^@ http://purl.uniprot.org/uniprot/E0TEN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/314260:PB2503_RS11530 ^@ http://purl.uniprot.org/uniprot/E0TEI9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/314260:PB2503_RS01135 ^@ http://purl.uniprot.org/uniprot/E0TBM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/314260:PB2503_RS07365 ^@ http://purl.uniprot.org/uniprot/E0TH48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS06595 ^@ http://purl.uniprot.org/uniprot/E0TEB0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/314260:PB2503_RS09485 ^@ http://purl.uniprot.org/uniprot/E0TEW6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/314260:PB2503_RS04995 ^@ http://purl.uniprot.org/uniprot/E0TGC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS01890 ^@ http://purl.uniprot.org/uniprot/E0TCB5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/314260:PB2503_RS12220 ^@ http://purl.uniprot.org/uniprot/E0TFM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS01035 ^@ http://purl.uniprot.org/uniprot/E0TBK5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/314260:PB2503_RS08910 ^@ http://purl.uniprot.org/uniprot/E0TDC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/314260:PB2503_RS08535 ^@ http://purl.uniprot.org/uniprot/E0TCS9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/314260:PB2503_RS07385 ^@ http://purl.uniprot.org/uniprot/E0TH52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/314260:PB2503_RS05190 ^@ http://purl.uniprot.org/uniprot/E0TGW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS07710 ^@ http://purl.uniprot.org/uniprot/E0TIB6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS08095 ^@ http://purl.uniprot.org/uniprot/E0TBQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP J family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS07475 ^@ http://purl.uniprot.org/uniprot/E0TH69 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/314260:PB2503_RS12810 ^@ http://purl.uniprot.org/uniprot/E0TGV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS01360 ^@ http://purl.uniprot.org/uniprot/E0TBV1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS03765 ^@ http://purl.uniprot.org/uniprot/E0TEN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS11110 ^@ http://purl.uniprot.org/uniprot/E0TDF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02875 ^@ http://purl.uniprot.org/uniprot/E0TDI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/314260:PB2503_RS00705 ^@ http://purl.uniprot.org/uniprot/E0TBB5 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/314260:PB2503_RS00630 ^@ http://purl.uniprot.org/uniprot/E0TBA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02685 ^@ http://purl.uniprot.org/uniprot/E0TD47 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/314260:PB2503_RS07300 ^@ http://purl.uniprot.org/uniprot/E0TGK1 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/314260:PB2503_RS04110 ^@ http://purl.uniprot.org/uniprot/E0TF72 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/314260:PB2503_RS13360 ^@ http://purl.uniprot.org/uniprot/E0TI15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12955 ^@ http://purl.uniprot.org/uniprot/E0THE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell inner membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/314260:PB2503_RS01675 ^@ http://purl.uniprot.org/uniprot/E0TC73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12830 ^@ http://purl.uniprot.org/uniprot/E0TGV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02500 ^@ http://purl.uniprot.org/uniprot/E0TD11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/314260:PB2503_RS06245 ^@ http://purl.uniprot.org/uniprot/E0TI76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/314260:PB2503_RS02115 ^@ http://purl.uniprot.org/uniprot/E0TCK4 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the reversible phosphorylation of pyruvate and phosphate. http://togogenome.org/gene/314260:PB2503_RS10125 ^@ http://purl.uniprot.org/uniprot/E0TH97 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/314260:PB2503_RS03415 ^@ http://purl.uniprot.org/uniprot/E0TE31 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/314260:PB2503_RS05715 ^@ http://purl.uniprot.org/uniprot/E0THL5 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/314260:PB2503_RS12255 ^@ http://purl.uniprot.org/uniprot/E0TG24 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS08210 ^@ http://purl.uniprot.org/uniprot/E0TC07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS00975 ^@ http://purl.uniprot.org/uniprot/E0TBJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09245 ^@ http://purl.uniprot.org/uniprot/E0TDU5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.|||Homotetramer formed by a dimer of dimers. http://togogenome.org/gene/314260:PB2503_RS06720 ^@ http://purl.uniprot.org/uniprot/E0TET8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/314260:PB2503_RS09375 ^@ http://purl.uniprot.org/uniprot/E0TEF1 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/314260:PB2503_RS09695 ^@ http://purl.uniprot.org/uniprot/E0TFY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS11480 ^@ http://purl.uniprot.org/uniprot/E0TEH9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS09415 ^@ http://purl.uniprot.org/uniprot/E0TEF9 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/314260:PB2503_RS11740 ^@ http://purl.uniprot.org/uniprot/E0TF18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS05805 ^@ http://purl.uniprot.org/uniprot/E0THN2 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/314260:PB2503_RS13540 ^@ http://purl.uniprot.org/uniprot/E0TIK5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS02100 ^@ http://purl.uniprot.org/uniprot/E0TCK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS12535 ^@ http://purl.uniprot.org/uniprot/E0TGP4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS12940 ^@ http://purl.uniprot.org/uniprot/E0THE5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS12515 ^@ http://purl.uniprot.org/uniprot/E0TG78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10370 ^@ http://purl.uniprot.org/uniprot/E0THU2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS09740 ^@ http://purl.uniprot.org/uniprot/E0TFZ4 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/314260:PB2503_RS04350 ^@ http://purl.uniprot.org/uniprot/E0TFC2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/314260:PB2503_RS12330 ^@ http://purl.uniprot.org/uniprot/E0TG39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/314260:PB2503_RS06285 ^@ http://purl.uniprot.org/uniprot/E0TI84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12230 ^@ http://purl.uniprot.org/uniprot/E0TG20 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/314260:PB2503_RS06145 ^@ http://purl.uniprot.org/uniprot/E0TI55 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS03745 ^@ http://purl.uniprot.org/uniprot/E0TEN5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS03045 ^@ http://purl.uniprot.org/uniprot/E0TDM0 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/314260:PB2503_RS04215 ^@ http://purl.uniprot.org/uniprot/E0TF94 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/314260:PB2503_RS13200 ^@ http://purl.uniprot.org/uniprot/E0THY4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/314260:PB2503_RS02535 ^@ http://purl.uniprot.org/uniprot/E0TD18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS03560 ^@ http://purl.uniprot.org/uniprot/E0TE60 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/314260:PB2503_RS08185 ^@ http://purl.uniprot.org/uniprot/E0TC02 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/314260:PB2503_RS07680 ^@ http://purl.uniprot.org/uniprot/E0TIB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS09785 ^@ http://purl.uniprot.org/uniprot/E0TG04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/314260:PB2503_RS02345 ^@ http://purl.uniprot.org/uniprot/E0TCQ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/314260:PB2503_RS06675 ^@ http://purl.uniprot.org/uniprot/E0TEC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/314260:PB2503_RS04115 ^@ http://purl.uniprot.org/uniprot/E0TF73 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS07855 ^@ http://purl.uniprot.org/uniprot/E0TBD3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS00195 ^@ http://purl.uniprot.org/uniprot/E0TB12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/314260:PB2503_RS05010 ^@ http://purl.uniprot.org/uniprot/E0TGC9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/314260:PB2503_RS13255 ^@ http://purl.uniprot.org/uniprot/E0THZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS12320 ^@ http://purl.uniprot.org/uniprot/E0TG37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS04120 ^@ http://purl.uniprot.org/uniprot/E0TF74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/314260:PB2503_RS07310 ^@ http://purl.uniprot.org/uniprot/E0TGK3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/314260:PB2503_RS12245 ^@ http://purl.uniprot.org/uniprot/E0TG22 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS08915 ^@ http://purl.uniprot.org/uniprot/E0TDC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/314260:PB2503_RS02120 ^@ http://purl.uniprot.org/uniprot/E0TCK5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/314260:PB2503_RS12620 ^@ http://purl.uniprot.org/uniprot/E0TGR1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/314260:PB2503_RS05970 ^@ http://purl.uniprot.org/uniprot/E0TI20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS01975 ^@ http://purl.uniprot.org/uniprot/E0TCD2 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/314260:PB2503_RS01280 ^@ http://purl.uniprot.org/uniprot/E0TBT5 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/314260:PB2503_RS15060 ^@ http://purl.uniprot.org/uniprot/E0THC5 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/314260:PB2503_RS02080 ^@ http://purl.uniprot.org/uniprot/E0TCJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10235 ^@ http://purl.uniprot.org/uniprot/E0THB9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/314260:PB2503_RS02455 ^@ http://purl.uniprot.org/uniprot/E0TD03 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/314260:PB2503_RS00645 ^@ http://purl.uniprot.org/uniprot/E0TBA5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/314260:PB2503_RS06760 ^@ http://purl.uniprot.org/uniprot/E0TEU6 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/314260:PB2503_RS10780 ^@ http://purl.uniprot.org/uniprot/E0TCG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02755 ^@ http://purl.uniprot.org/uniprot/E0TD60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08930 ^@ http://purl.uniprot.org/uniprot/E0TDC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/314260:PB2503_RS03925 ^@ http://purl.uniprot.org/uniprot/E0TES0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS05860 ^@ http://purl.uniprot.org/uniprot/E0THP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/314260:PB2503_RS07750 ^@ http://purl.uniprot.org/uniprot/E0TIC4 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS07990 ^@ http://purl.uniprot.org/uniprot/E0TBF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS04145 ^@ http://purl.uniprot.org/uniprot/E0TF79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/314260:PB2503_RS06495 ^@ http://purl.uniprot.org/uniprot/E0TE91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02855 ^@ http://purl.uniprot.org/uniprot/E0TDI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/314260:PB2503_RS07305 ^@ http://purl.uniprot.org/uniprot/E0TGK2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/314260:PB2503_RS13025 ^@ http://purl.uniprot.org/uniprot/E0THG2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS03240 ^@ http://purl.uniprot.org/uniprot/E0TDZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS07840 ^@ http://purl.uniprot.org/uniprot/E0TB52 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/314260:PB2503_RS05000 ^@ http://purl.uniprot.org/uniprot/E0TGC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/314260:PB2503_RS04970 ^@ http://purl.uniprot.org/uniprot/E0TGC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/314260:PB2503_RS04485 ^@ http://purl.uniprot.org/uniprot/E0TFQ2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS00740 ^@ http://purl.uniprot.org/uniprot/E0TBC3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/314260:PB2503_RS01900 ^@ http://purl.uniprot.org/uniprot/E0TCB7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/314260:PB2503_RS07675 ^@ http://purl.uniprot.org/uniprot/E0TIA9 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/314260:PB2503_RS00785 ^@ http://purl.uniprot.org/uniprot/E0TBD2 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/314260:PB2503_RS08445 ^@ http://purl.uniprot.org/uniprot/E0TCR1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/314260:PB2503_RS11365 ^@ http://purl.uniprot.org/uniprot/E0TDX9 ^@ Cofactor|||Similarity ^@ Belongs to the alkaline phosphatase family.|||Binds 1 Mg(2+) ion.|||Binds 2 Zn(2+) ions. http://togogenome.org/gene/314260:PB2503_RS03570 ^@ http://purl.uniprot.org/uniprot/E0TE62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/314260:PB2503_RS02475 ^@ http://purl.uniprot.org/uniprot/E0TD06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/314260:PB2503_RS11320 ^@ http://purl.uniprot.org/uniprot/E0TDX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS01145 ^@ http://purl.uniprot.org/uniprot/E0TBM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS08400 ^@ http://purl.uniprot.org/uniprot/E0TCF0 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/314260:PB2503_RS09195 ^@ http://purl.uniprot.org/uniprot/E0TDT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/314260:PB2503_RS04045 ^@ http://purl.uniprot.org/uniprot/E0TF59 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/314260:PB2503_RS08990 ^@ http://purl.uniprot.org/uniprot/E0TDD6 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/314260:PB2503_RS05755 ^@ http://purl.uniprot.org/uniprot/E0THM3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS01345 ^@ http://purl.uniprot.org/uniprot/E0TBU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS09930 ^@ http://purl.uniprot.org/uniprot/E0TGL9 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/314260:PB2503_RS02655 ^@ http://purl.uniprot.org/uniprot/E0TD42 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/314260:PB2503_RS12530 ^@ http://purl.uniprot.org/uniprot/E0TG81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS02890 ^@ http://purl.uniprot.org/uniprot/E0TDJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS05735 ^@ http://purl.uniprot.org/uniprot/E0THL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/314260:PB2503_RS09305 ^@ http://purl.uniprot.org/uniprot/E0TED8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/314260:PB2503_RS02720 ^@ http://purl.uniprot.org/uniprot/E0TD53 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/314260:PB2503_RS03550 ^@ http://purl.uniprot.org/uniprot/E0TE58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/314260:PB2503_RS11830 ^@ http://purl.uniprot.org/uniprot/E0TF36 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/314260:PB2503_RS07870 ^@ http://purl.uniprot.org/uniprot/E0TBD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS00620 ^@ http://purl.uniprot.org/uniprot/E0TBA0 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/314260:PB2503_RS04090 ^@ http://purl.uniprot.org/uniprot/E0TF68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/314260:PB2503_RS08030 ^@ http://purl.uniprot.org/uniprot/E0TBP3 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/314260:PB2503_RS11080 ^@ http://purl.uniprot.org/uniprot/E0TCY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS03885 ^@ http://purl.uniprot.org/uniprot/E0TER2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08755 ^@ http://purl.uniprot.org/uniprot/E0TD89 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS09455 ^@ http://purl.uniprot.org/uniprot/E0TEW0 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/314260:PB2503_RS03105 ^@ http://purl.uniprot.org/uniprot/E0TDN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS11535 ^@ http://purl.uniprot.org/uniprot/E0TEJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS07035 ^@ http://purl.uniprot.org/uniprot/E0TFX3 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/314260:PB2503_RS04765 ^@ http://purl.uniprot.org/uniprot/E0TFV9 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS13045 ^@ http://purl.uniprot.org/uniprot/E0THG6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/314260:PB2503_RS07470 ^@ http://purl.uniprot.org/uniprot/E0TH68 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/314260:PB2503_RS03910 ^@ http://purl.uniprot.org/uniprot/E0TER7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS12560 ^@ http://purl.uniprot.org/uniprot/E0TGP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS10330 ^@ http://purl.uniprot.org/uniprot/E0THT6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS07250 ^@ http://purl.uniprot.org/uniprot/E0TGJ2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/314260:PB2503_RS08940 ^@ http://purl.uniprot.org/uniprot/E0TDC6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/314260:PB2503_RS03705 ^@ http://purl.uniprot.org/uniprot/E0TEM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/314260:PB2503_RS03630 ^@ http://purl.uniprot.org/uniprot/E0TEL2 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/314260:PB2503_RS00735 ^@ http://purl.uniprot.org/uniprot/E0TBC2 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/314260:PB2503_RS00325 ^@ http://purl.uniprot.org/uniprot/E0TB36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/314260:PB2503_RS08570 ^@ http://purl.uniprot.org/uniprot/E0TCT7 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/314260:PB2503_RS12175 ^@ http://purl.uniprot.org/uniprot/E0TFM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/314260:PB2503_RS07060 ^@ http://purl.uniprot.org/uniprot/E0TFX6 ^@ Function ^@ Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. http://togogenome.org/gene/314260:PB2503_RS02065 ^@ http://purl.uniprot.org/uniprot/E0TCJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02765 ^@ http://purl.uniprot.org/uniprot/E0TD62 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS03965 ^@ http://purl.uniprot.org/uniprot/E0TES8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/314260:PB2503_RS05600 ^@ http://purl.uniprot.org/uniprot/E0THJ2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/314260:PB2503_RS07330 ^@ http://purl.uniprot.org/uniprot/E0TH42 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/314260:PB2503_RS05790 ^@ http://purl.uniprot.org/uniprot/E0THM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/314260:PB2503_RS05070 ^@ http://purl.uniprot.org/uniprot/E0TGE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/314260:PB2503_RS03120 ^@ http://purl.uniprot.org/uniprot/E0TDN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbL/VirB6 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS13720 ^@ http://purl.uniprot.org/uniprot/E0TD52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/314260:PB2503_RS13880 ^@ http://purl.uniprot.org/uniprot/E0THM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12250 ^@ http://purl.uniprot.org/uniprot/E0TG23 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/314260:PB2503_RS08045 ^@ http://purl.uniprot.org/uniprot/E0TBP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/314260:PB2503_RS03680 ^@ http://purl.uniprot.org/uniprot/E0TEM2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/314260:PB2503_RS01570 ^@ http://purl.uniprot.org/uniprot/E0TBZ2 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/314260:PB2503_RS02265 ^@ http://purl.uniprot.org/uniprot/E0TCN4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/314260:PB2503_RS09860 ^@ http://purl.uniprot.org/uniprot/E0TG18 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/314260:PB2503_RS13150 ^@ http://purl.uniprot.org/uniprot/E0THX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS03115 ^@ http://purl.uniprot.org/uniprot/E0TDN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS06515 ^@ http://purl.uniprot.org/uniprot/E0TE95 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS06830 ^@ http://purl.uniprot.org/uniprot/E0TFD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS04035 ^@ http://purl.uniprot.org/uniprot/E0TF57 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/314260:PB2503_RS06650 ^@ http://purl.uniprot.org/uniprot/E0TEC1 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/314260:PB2503_RS02215 ^@ http://purl.uniprot.org/uniprot/E0TCM4 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/314260:PB2503_RS08490 ^@ http://purl.uniprot.org/uniprot/E0TCS1 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/314260:PB2503_RS12290 ^@ http://purl.uniprot.org/uniprot/E0TG31 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/314260:PB2503_RS00940 ^@ http://purl.uniprot.org/uniprot/E0TBI8 ^@ Similarity ^@ Belongs to the transglycosylase Slt family.|||Belongs to the virb1 family. http://togogenome.org/gene/314260:PB2503_RS14005 ^@ http://purl.uniprot.org/uniprot/E0TCS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS10680 ^@ http://purl.uniprot.org/uniprot/E0TC40 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/314260:PB2503_RS00835 ^@ http://purl.uniprot.org/uniprot/E0TBG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/314260:PB2503_RS03325 ^@ http://purl.uniprot.org/uniprot/E0TE13 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/314260:PB2503_RS11050 ^@ http://purl.uniprot.org/uniprot/E0TCY4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/314260:PB2503_RS12545 ^@ http://purl.uniprot.org/uniprot/E0TGP6 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/314260:PB2503_RS12880 ^@ http://purl.uniprot.org/uniprot/E0THD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS05370 ^@ http://purl.uniprot.org/uniprot/E0TGZ7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS11265 ^@ http://purl.uniprot.org/uniprot/E0TDV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS00745 ^@ http://purl.uniprot.org/uniprot/E0TBC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS09160 ^@ http://purl.uniprot.org/uniprot/E0TDS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS13920 ^@ http://purl.uniprot.org/uniprot/E0TET4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS08760 ^@ http://purl.uniprot.org/uniprot/E0TD90 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/314260:PB2503_RS01965 ^@ http://purl.uniprot.org/uniprot/E0TCD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/314260:PB2503_RS07445 ^@ http://purl.uniprot.org/uniprot/E0TH63 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/314260:PB2503_RS12860 ^@ http://purl.uniprot.org/uniprot/E0TGW0 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/314260:PB2503_RS09995 ^@ http://purl.uniprot.org/uniprot/E0TGN0 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/314260:PB2503_RS12570 ^@ http://purl.uniprot.org/uniprot/E0TGQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/314260:PB2503_RS10225 ^@ http://purl.uniprot.org/uniprot/E0THB7 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/314260:PB2503_RS01080 ^@ http://purl.uniprot.org/uniprot/E0TBL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS13340 ^@ http://purl.uniprot.org/uniprot/E0TI10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/314260:PB2503_RS07720 ^@ http://purl.uniprot.org/uniprot/E0TIB8 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/314260:PB2503_RS05980 ^@ http://purl.uniprot.org/uniprot/E0TI22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/314260:PB2503_RS01985 ^@ http://purl.uniprot.org/uniprot/E0TCD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS02230 ^@ http://purl.uniprot.org/uniprot/E0TCM7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/314260:PB2503_RS01260 ^@ http://purl.uniprot.org/uniprot/E0TBT1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/314260:PB2503_RS08240 ^@ http://purl.uniprot.org/uniprot/E0TC14 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/314260:PB2503_RS08595 ^@ http://purl.uniprot.org/uniprot/E0TCU2 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/314260:PB2503_RS01765 ^@ http://purl.uniprot.org/uniprot/E0TC91 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/314260:PB2503_RS01160 ^@ http://purl.uniprot.org/uniprot/E0TBN0 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/314260:PB2503_RS02150 ^@ http://purl.uniprot.org/uniprot/E0TCL1 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/314260:PB2503_RS07230 ^@ http://purl.uniprot.org/uniprot/E0TGI9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/314260:PB2503_RS08010 ^@ http://purl.uniprot.org/uniprot/E0TBN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS08855 ^@ http://purl.uniprot.org/uniprot/E0TDB0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/314260:PB2503_RS10280 ^@ http://purl.uniprot.org/uniprot/E0THC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/314260:PB2503_RS09520 ^@ http://purl.uniprot.org/uniprot/E0TEX3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS09625 ^@ http://purl.uniprot.org/uniprot/E0TFG5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/314260:PB2503_RS08300 ^@ http://purl.uniprot.org/uniprot/E0TC26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/314260:PB2503_RS05740 ^@ http://purl.uniprot.org/uniprot/E0THM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the O-antigen polymerase family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS00380 ^@ http://purl.uniprot.org/uniprot/E0TB47 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/314260:PB2503_RS08580 ^@ http://purl.uniprot.org/uniprot/E0TCT9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/314260:PB2503_RS10590 ^@ http://purl.uniprot.org/uniprot/E0TIG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.|||Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).|||Homodimer or monomer when oxidized or reduced, respectively.|||chloroplast http://togogenome.org/gene/314260:PB2503_RS03640 ^@ http://purl.uniprot.org/uniprot/E0TEL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/314260:PB2503_RS02945 ^@ http://purl.uniprot.org/uniprot/E0TDK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS07140 ^@ http://purl.uniprot.org/uniprot/E0TGH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/314260:PB2503_RS11245 ^@ http://purl.uniprot.org/uniprot/E0TDV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/314260:PB2503_RS08960 ^@ http://purl.uniprot.org/uniprot/E0TDD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/314260:PB2503_RS12595 ^@ http://purl.uniprot.org/uniprot/E0TGQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09855 ^@ http://purl.uniprot.org/uniprot/E0TG17 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/314260:PB2503_RS06160 ^@ http://purl.uniprot.org/uniprot/E0TI58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/314260:PB2503_RS09440 ^@ http://purl.uniprot.org/uniprot/E0TEV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/314260:PB2503_RS09905 ^@ http://purl.uniprot.org/uniprot/E0TGL4 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/314260:PB2503_RS06360 ^@ http://purl.uniprot.org/uniprot/E0TI99 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus membrane http://togogenome.org/gene/314260:PB2503_RS10435 ^@ http://purl.uniprot.org/uniprot/E0THV5 ^@ Similarity ^@ Belongs to the sterol desaturase family. http://togogenome.org/gene/314260:PB2503_RS04720 ^@ http://purl.uniprot.org/uniprot/E0TFV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/314260:PB2503_RS07160 ^@ http://purl.uniprot.org/uniprot/E0TGH6 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/314260:PB2503_RS12985 ^@ http://purl.uniprot.org/uniprot/E0THF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/314260:PB2503_RS03935 ^@ http://purl.uniprot.org/uniprot/E0TES2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/314260:PB2503_RS11875 ^@ http://purl.uniprot.org/uniprot/E0TF45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/314260:PB2503_RS08510 ^@ http://purl.uniprot.org/uniprot/E0TCS5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily. http://togogenome.org/gene/314260:PB2503_RS11820 ^@ http://purl.uniprot.org/uniprot/E0TF34 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/314260:PB2503_RS04010 ^@ http://purl.uniprot.org/uniprot/E0TF52 ^@ Subcellular Location Annotation ^@ Membrane