http://togogenome.org/gene/323098:NWI_RS00180 ^@ http://purl.uniprot.org/uniprot/Q3SWP0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/323098:NWI_RS07985 ^@ http://purl.uniprot.org/uniprot/Q3SSE6 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/323098:NWI_RS09170 ^@ http://purl.uniprot.org/uniprot/Q3SRS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/323098:NWI_RS15275 ^@ http://purl.uniprot.org/uniprot/Q3SNF5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS09825 ^@ http://purl.uniprot.org/uniprot/Q3SRE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS02230 ^@ http://purl.uniprot.org/uniprot/Q3SVJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/323098:NWI_RS03120 ^@ http://purl.uniprot.org/uniprot/Q3SV25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/323098:NWI_RS08580 ^@ http://purl.uniprot.org/uniprot/Q3SS37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/323098:NWI_RS03005 ^@ http://purl.uniprot.org/uniprot/Q3SV48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/323098:NWI_RS09395 ^@ http://purl.uniprot.org/uniprot/Q3SRN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/323098:NWI_RS06375 ^@ http://purl.uniprot.org/uniprot/Q3ST95 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/323098:NWI_RS05685 ^@ http://purl.uniprot.org/uniprot/Q3STM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/323098:NWI_RS12055 ^@ http://purl.uniprot.org/uniprot/Q3SQ73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS03115 ^@ http://purl.uniprot.org/uniprot/Q3SV26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS10350 ^@ http://purl.uniprot.org/uniprot/Q3SR47 ^@ Similarity ^@ Belongs to the CsoS2 family. http://togogenome.org/gene/323098:NWI_RS10010 ^@ http://purl.uniprot.org/uniprot/Q3SRB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS13265 ^@ http://purl.uniprot.org/uniprot/Q3SPI8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/323098:NWI_RS09805 ^@ http://purl.uniprot.org/uniprot/Q3SRF0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS04550 ^@ http://purl.uniprot.org/uniprot/Q3SUA1 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/323098:NWI_RS11050 ^@ http://purl.uniprot.org/uniprot/Q3SQR8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS06895 ^@ http://purl.uniprot.org/uniprot/Q3ST00 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS04750 ^@ http://purl.uniprot.org/uniprot/Q3SU64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS01150 ^@ http://purl.uniprot.org/uniprot/Q3SW54 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/323098:NWI_RS02045 ^@ http://purl.uniprot.org/uniprot/Q3SVM9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS13505 ^@ http://purl.uniprot.org/uniprot/Q3SPD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS00680 ^@ http://purl.uniprot.org/uniprot/Q3SWE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08335 ^@ http://purl.uniprot.org/uniprot/Q3SS83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS07180 ^@ http://purl.uniprot.org/uniprot/Q3SSU5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS10805 ^@ http://purl.uniprot.org/uniprot/Q3SQW4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell inner membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/323098:NWI_RS05745 ^@ http://purl.uniprot.org/uniprot/Q3STL3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS09780 ^@ http://purl.uniprot.org/uniprot/Q3SRF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS02300 ^@ http://purl.uniprot.org/uniprot/Q3SVI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS15080 ^@ http://purl.uniprot.org/uniprot/Q3SNI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS06390 ^@ http://purl.uniprot.org/uniprot/Q3ST92 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/323098:NWI_RS06900 ^@ http://purl.uniprot.org/uniprot/Q3SSZ9 ^@ Similarity ^@ Belongs to the virb1 family. http://togogenome.org/gene/323098:NWI_RS01930 ^@ http://purl.uniprot.org/uniprot/Q3SVQ4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS05830 ^@ http://purl.uniprot.org/uniprot/Q3STJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure. http://togogenome.org/gene/323098:NWI_RS12205 ^@ http://purl.uniprot.org/uniprot/Q3SQ44 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/323098:NWI_RS03140 ^@ http://purl.uniprot.org/uniprot/Q3SV21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08190 ^@ http://purl.uniprot.org/uniprot/Q3SSB4 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/323098:NWI_RS07540 ^@ http://purl.uniprot.org/uniprot/Q3SSM5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/323098:NWI_RS09815 ^@ http://purl.uniprot.org/uniprot/Q3SRE8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/323098:NWI_RS00235 ^@ http://purl.uniprot.org/uniprot/Q3SWM9 ^@ Function|||Similarity ^@ Belongs to the dUTPase family.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/323098:NWI_RS06780 ^@ http://purl.uniprot.org/uniprot/Q3ST24 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/323098:NWI_RS12615 ^@ http://purl.uniprot.org/uniprot/Q3SPW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02645 ^@ http://purl.uniprot.org/uniprot/Q3SVB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.|||Cell inner membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/323098:NWI_RS12485 ^@ http://purl.uniprot.org/uniprot/Q3SPY6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/323098:NWI_RS00085 ^@ http://purl.uniprot.org/uniprot/Q3SWQ8 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/323098:NWI_RS01525 ^@ http://purl.uniprot.org/uniprot/Q3SVY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/323098:NWI_RS15560 ^@ http://purl.uniprot.org/uniprot/Q3SNA1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS09690 ^@ http://purl.uniprot.org/uniprot/Q3SRH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS13965 ^@ http://purl.uniprot.org/uniprot/Q3SP50 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/323098:NWI_RS15890 ^@ http://purl.uniprot.org/uniprot/Q3SN39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS08675 ^@ http://purl.uniprot.org/uniprot/Q3SS18 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/323098:NWI_RS09120 ^@ http://purl.uniprot.org/uniprot/Q3SRT3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/323098:NWI_RS09685 ^@ http://purl.uniprot.org/uniprot/Q3SRH4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/323098:NWI_RS09935 ^@ http://purl.uniprot.org/uniprot/Q3SRC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer.|||In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. http://togogenome.org/gene/323098:NWI_RS11450 ^@ http://purl.uniprot.org/uniprot/Q3SQJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/323098:NWI_RS10500 ^@ http://purl.uniprot.org/uniprot/Q3SR18 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/323098:NWI_RS01960 ^@ http://purl.uniprot.org/uniprot/Q3SVP7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/323098:NWI_RS05080 ^@ http://purl.uniprot.org/uniprot/Q3SU00 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/323098:NWI_RS13440 ^@ http://purl.uniprot.org/uniprot/Q3SPF2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/323098:NWI_RS14910 ^@ http://purl.uniprot.org/uniprot/Q3SNM3 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/323098:NWI_RS13605 ^@ http://purl.uniprot.org/uniprot/Q3SPB9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS15935 ^@ http://purl.uniprot.org/uniprot/Q3SN32 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/323098:NWI_RS05440 ^@ http://purl.uniprot.org/uniprot/Q3STS4 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/323098:NWI_RS13240 ^@ http://purl.uniprot.org/uniprot/Q3SPJ3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/323098:NWI_RS13385 ^@ http://purl.uniprot.org/uniprot/Q3SPG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/323098:NWI_RS12840 ^@ http://purl.uniprot.org/uniprot/Q3SPS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/323098:NWI_RS00645 ^@ http://purl.uniprot.org/uniprot/Q3SWF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/323098:NWI_RS09720 ^@ http://purl.uniprot.org/uniprot/Q3SRG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/323098:NWI_RS10680 ^@ http://purl.uniprot.org/uniprot/Q3SQY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS11255 ^@ http://purl.uniprot.org/uniprot/Q3SQM9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS16230 ^@ http://purl.uniprot.org/uniprot/Q3SMW9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/323098:NWI_RS01655 ^@ http://purl.uniprot.org/uniprot/Q3SVV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/323098:NWI_RS09445 ^@ http://purl.uniprot.org/uniprot/Q3SRM1 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/323098:NWI_RS15955 ^@ http://purl.uniprot.org/uniprot/Q3SN28 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/323098:NWI_RS03050 ^@ http://purl.uniprot.org/uniprot/Q3SV39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/323098:NWI_RS10110 ^@ http://purl.uniprot.org/uniprot/Q3SR95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/323098:NWI_RS02700 ^@ http://purl.uniprot.org/uniprot/Q3SVA4 ^@ Function ^@ Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY. http://togogenome.org/gene/323098:NWI_RS10355 ^@ http://purl.uniprot.org/uniprot/Q3SR46 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO small chain family.|||Heterohexadecamer of 8 large and 8 small subunits.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/323098:NWI_RS05515 ^@ http://purl.uniprot.org/uniprot/Q3STQ9 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS01850 ^@ http://purl.uniprot.org/uniprot/Q3SVR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/323098:NWI_RS07160 ^@ http://purl.uniprot.org/uniprot/Q3SSU9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/323098:NWI_RS06240 ^@ http://purl.uniprot.org/uniprot/Q3STC1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/323098:NWI_RS09990 ^@ http://purl.uniprot.org/uniprot/Q3SRB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/323098:NWI_RS00015 ^@ http://purl.uniprot.org/uniprot/Q3SMV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/323098:NWI_RS05150 ^@ http://purl.uniprot.org/uniprot/Q3STY3 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/323098:NWI_RS14190 ^@ http://purl.uniprot.org/uniprot/Q3SP07 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/323098:NWI_RS04015 ^@ http://purl.uniprot.org/uniprot/Q3SUK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS11285 ^@ http://purl.uniprot.org/uniprot/Q3SQM3 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/323098:NWI_RS13325 ^@ http://purl.uniprot.org/uniprot/Q3SPH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS05145 ^@ http://purl.uniprot.org/uniprot/Q3STY4 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/323098:NWI_RS12640 ^@ http://purl.uniprot.org/uniprot/Q3SPV7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/323098:NWI_RS02380 ^@ http://purl.uniprot.org/uniprot/Q3SVG7 ^@ Similarity ^@ Belongs to the CmpA/NrtA family. http://togogenome.org/gene/323098:NWI_RS09235 ^@ http://purl.uniprot.org/uniprot/Q3SRR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/323098:NWI_RS11305 ^@ http://purl.uniprot.org/uniprot/Q3SQM0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/323098:NWI_RS09315 ^@ http://purl.uniprot.org/uniprot/Q3SRP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/323098:NWI_RS09410 ^@ http://purl.uniprot.org/uniprot/Q3SRM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS04665 ^@ http://purl.uniprot.org/uniprot/Q3SU79 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/323098:NWI_RS01070 ^@ http://purl.uniprot.org/uniprot/Q3SW68 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/323098:NWI_RS10925 ^@ http://purl.uniprot.org/uniprot/Q3SQU2 ^@ Similarity ^@ Belongs to the TrbG/VirB9 family. http://togogenome.org/gene/323098:NWI_RS01645 ^@ http://purl.uniprot.org/uniprot/Q3SVW0 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/323098:NWI_RS07185 ^@ http://purl.uniprot.org/uniprot/Q3SSU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/323098:NWI_RS01030 ^@ http://purl.uniprot.org/uniprot/Q3SW76 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/323098:NWI_RS02190 ^@ http://purl.uniprot.org/uniprot/Q3SVK1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/323098:NWI_RS07070 ^@ http://purl.uniprot.org/uniprot/Q3SSW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS05435 ^@ http://purl.uniprot.org/uniprot/Q3STS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS00560 ^@ http://purl.uniprot.org/uniprot/Q3SWG8 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/323098:NWI_RS13740 ^@ http://purl.uniprot.org/uniprot/Q3SP93 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/323098:NWI_RS15970 ^@ http://purl.uniprot.org/uniprot/Q3SN25 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS13495 ^@ http://purl.uniprot.org/uniprot/Q3SPE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS05790 ^@ http://purl.uniprot.org/uniprot/Q3STK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS13275 ^@ http://purl.uniprot.org/uniprot/Q3SPI6 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/323098:NWI_RS06875 ^@ http://purl.uniprot.org/uniprot/Q3ST04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/323098:NWI_RS04600 ^@ http://purl.uniprot.org/uniprot/Q3SU92 ^@ Similarity ^@ Belongs to the TULIP P47 family. http://togogenome.org/gene/323098:NWI_RS09795 ^@ http://purl.uniprot.org/uniprot/Q3SRF2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS05400 ^@ http://purl.uniprot.org/uniprot/Q3STT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/323098:NWI_RS11685 ^@ http://purl.uniprot.org/uniprot/Q3SQE7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/323098:NWI_RS07490 ^@ http://purl.uniprot.org/uniprot/Q3SSN5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/323098:NWI_RS03105 ^@ http://purl.uniprot.org/uniprot/Q3SV28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS07145 ^@ http://purl.uniprot.org/uniprot/Q3SSV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/323098:NWI_RS06225 ^@ http://purl.uniprot.org/uniprot/Q3STC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS03335 ^@ http://purl.uniprot.org/uniprot/Q3SUY2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/323098:NWI_RS02605 ^@ http://purl.uniprot.org/uniprot/Q3SVC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide deacetylase family.|||Cytoplasm|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/323098:NWI_RS01295 ^@ http://purl.uniprot.org/uniprot/Q3SW26 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/323098:NWI_RS14455 ^@ http://purl.uniprot.org/uniprot/Q3SNV3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/323098:NWI_RS03915 ^@ http://purl.uniprot.org/uniprot/Q3SUM2 ^@ Cofactor|||Similarity ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer. http://togogenome.org/gene/323098:NWI_RS05460 ^@ http://purl.uniprot.org/uniprot/Q3STS0 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/323098:NWI_RS13295 ^@ http://purl.uniprot.org/uniprot/Q3SPI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/323098:NWI_RS04540 ^@ http://purl.uniprot.org/uniprot/Q3SUA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS12090 ^@ http://purl.uniprot.org/uniprot/Q3SQ66 ^@ Similarity ^@ Belongs to the amidinotransferase family. http://togogenome.org/gene/323098:NWI_RS10495 ^@ http://purl.uniprot.org/uniprot/Q3SR19 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/323098:NWI_RS01020 ^@ http://purl.uniprot.org/uniprot/Q3SW78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/323098:NWI_RS07060 ^@ http://purl.uniprot.org/uniprot/Q3SSW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS01160 ^@ http://purl.uniprot.org/uniprot/Q3SW52 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/323098:NWI_RS00755 ^@ http://purl.uniprot.org/uniprot/Q3SWC9 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/323098:NWI_RS10470 ^@ http://purl.uniprot.org/uniprot/Q3SR23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/323098:NWI_RS06420 ^@ http://purl.uniprot.org/uniprot/Q3ST86 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/323098:NWI_RS04605 ^@ http://purl.uniprot.org/uniprot/Q3SU91 ^@ Similarity ^@ Belongs to the TULIP P47 family. http://togogenome.org/gene/323098:NWI_RS13800 ^@ http://purl.uniprot.org/uniprot/Q3SP81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS02655 ^@ http://purl.uniprot.org/uniprot/Q3SVB3 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/323098:NWI_RS11655 ^@ http://purl.uniprot.org/uniprot/Q3SQF3 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/323098:NWI_RS15505 ^@ http://purl.uniprot.org/uniprot/Q3SNB0 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/323098:NWI_RS13515 ^@ http://purl.uniprot.org/uniprot/Q3SPD7 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/323098:NWI_RS11535 ^@ http://purl.uniprot.org/uniprot/Q3SQH5 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS00295 ^@ http://purl.uniprot.org/uniprot/Q3SWL7 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/323098:NWI_RS05500 ^@ http://purl.uniprot.org/uniprot/Q3STR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS07155 ^@ http://purl.uniprot.org/uniprot/Q3SSV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/323098:NWI_RS10360 ^@ http://purl.uniprot.org/uniprot/Q3SR45 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO large chain family. Type I subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterohexadecamer of 8 large chains and 8 small chains.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/323098:NWI_RS01035 ^@ http://purl.uniprot.org/uniprot/Q3SW75 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/323098:NWI_RS15895 ^@ http://purl.uniprot.org/uniprot/Q3SN38 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/323098:NWI_RS10505 ^@ http://purl.uniprot.org/uniprot/Q3SR17 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/323098:NWI_RS00185 ^@ http://purl.uniprot.org/uniprot/Q3SWN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/323098:NWI_RS08980 ^@ http://purl.uniprot.org/uniprot/Q3SRV8 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/323098:NWI_RS10860 ^@ http://purl.uniprot.org/uniprot/Q3SQV4 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/323098:NWI_RS10930 ^@ http://purl.uniprot.org/uniprot/Q3SQU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS04760 ^@ http://purl.uniprot.org/uniprot/Q3SU62 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/323098:NWI_RS02455 ^@ http://purl.uniprot.org/uniprot/Q3SVF2 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/323098:NWI_RS08685 ^@ http://purl.uniprot.org/uniprot/Q3SS16 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/323098:NWI_RS05775 ^@ http://purl.uniprot.org/uniprot/Q3STK7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/323098:NWI_RS08620 ^@ http://purl.uniprot.org/uniprot/Q3SS29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS05665 ^@ http://purl.uniprot.org/uniprot/Q3STM9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/323098:NWI_RS03165 ^@ http://purl.uniprot.org/uniprot/Q3SV17 ^@ Function|||Similarity ^@ Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/323098:NWI_RS02430 ^@ http://purl.uniprot.org/uniprot/Q3SVF7 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/323098:NWI_RS13785 ^@ http://purl.uniprot.org/uniprot/Q3SP84 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS12850 ^@ http://purl.uniprot.org/uniprot/Q3SPS0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS18120 ^@ http://purl.uniprot.org/uniprot/Q3SUP9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS11570 ^@ http://purl.uniprot.org/uniprot/Q3SQG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS06320 ^@ http://purl.uniprot.org/uniprot/Q3STA6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Maintains high levels of reduced glutathione. http://togogenome.org/gene/323098:NWI_RS00110 ^@ http://purl.uniprot.org/uniprot/Q3SWQ3 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/323098:NWI_RS06715 ^@ http://purl.uniprot.org/uniprot/Q3ST35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS13595 ^@ http://purl.uniprot.org/uniprot/Q3SPC1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/323098:NWI_RS00695 ^@ http://purl.uniprot.org/uniprot/Q3SWE1 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/323098:NWI_RS05420 ^@ http://purl.uniprot.org/uniprot/Q3STS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/323098:NWI_RS13520 ^@ http://purl.uniprot.org/uniprot/Q3SPD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS01665 ^@ http://purl.uniprot.org/uniprot/Q3SVV6 ^@ Similarity ^@ Belongs to the thioredoxin family. DsbE subfamily. http://togogenome.org/gene/323098:NWI_RS14100 ^@ http://purl.uniprot.org/uniprot/Q3SP24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Cell outer membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/323098:NWI_RS00670 ^@ http://purl.uniprot.org/uniprot/Q3SWE6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/323098:NWI_RS09465 ^@ http://purl.uniprot.org/uniprot/Q3SRL7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/323098:NWI_RS02785 ^@ http://purl.uniprot.org/uniprot/Q3SV88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS13990 ^@ http://purl.uniprot.org/uniprot/Q3SP45 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/323098:NWI_RS07095 ^@ http://purl.uniprot.org/uniprot/Q3SSW2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/323098:NWI_RS07000 ^@ http://purl.uniprot.org/uniprot/Q3SSY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/323098:NWI_RS12705 ^@ http://purl.uniprot.org/uniprot/Q3SPU7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/323098:NWI_RS02180 ^@ http://purl.uniprot.org/uniprot/Q3SVK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/323098:NWI_RS04925 ^@ http://purl.uniprot.org/uniprot/Q3SU28 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/323098:NWI_RS12780 ^@ http://purl.uniprot.org/uniprot/Q3SPT5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS15220 ^@ http://purl.uniprot.org/uniprot/Q3SNG3 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO small chain family.|||Heterohexadecamer of 8 large and 8 small subunits.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/323098:NWI_RS09055 ^@ http://purl.uniprot.org/uniprot/Q3SRU5 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/323098:NWI_RS11105 ^@ http://purl.uniprot.org/uniprot/Q3SQQ8 ^@ Similarity ^@ Belongs to the SBNO family. http://togogenome.org/gene/323098:NWI_RS06830 ^@ http://purl.uniprot.org/uniprot/Q3ST13 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/323098:NWI_RS01520 ^@ http://purl.uniprot.org/uniprot/Q3SVY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/323098:NWI_RS14490 ^@ http://purl.uniprot.org/uniprot/Q3SNU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/323098:NWI_RS15975 ^@ http://purl.uniprot.org/uniprot/Q3SN24 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/323098:NWI_RS05850 ^@ http://purl.uniprot.org/uniprot/Q3STJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/323098:NWI_RS11670 ^@ http://purl.uniprot.org/uniprot/Q3SQF0 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/323098:NWI_RS01755 ^@ http://purl.uniprot.org/uniprot/Q3SVT8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/323098:NWI_RS09580 ^@ http://purl.uniprot.org/uniprot/Q3SRJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/323098:NWI_RS08330 ^@ http://purl.uniprot.org/uniprot/Q3SS84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/323098:NWI_RS15465 ^@ http://purl.uniprot.org/uniprot/Q3SNB8 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/323098:NWI_RS02435 ^@ http://purl.uniprot.org/uniprot/Q3SVF6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/323098:NWI_RS14080 ^@ http://purl.uniprot.org/uniprot/Q3SP28 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS15580 ^@ http://purl.uniprot.org/uniprot/Q3SN97 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/323098:NWI_RS00810 ^@ http://purl.uniprot.org/uniprot/Q3SWC0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS09530 ^@ http://purl.uniprot.org/uniprot/Q3SRK4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/323098:NWI_RS09740 ^@ http://purl.uniprot.org/uniprot/Q3SRG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS03830 ^@ http://purl.uniprot.org/uniprot/Q3SUN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS04850 ^@ http://purl.uniprot.org/uniprot/Q3SU44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS02170 ^@ http://purl.uniprot.org/uniprot/Q3SVK5 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/323098:NWI_RS00730 ^@ http://purl.uniprot.org/uniprot/Q3SWD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS14445 ^@ http://purl.uniprot.org/uniprot/Q3SNV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/323098:NWI_RS14325 ^@ http://purl.uniprot.org/uniprot/Q3SNY0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/323098:NWI_RS10525 ^@ http://purl.uniprot.org/uniprot/Q3SR13 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/323098:NWI_RS10825 ^@ http://purl.uniprot.org/uniprot/Q3SQW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS00030 ^@ http://purl.uniprot.org/uniprot/Q3SMU7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/323098:NWI_RS03090 ^@ http://purl.uniprot.org/uniprot/Q3SV31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BA14k family.|||Cell membrane|||Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.|||Membrane http://togogenome.org/gene/323098:NWI_RS03920 ^@ http://purl.uniprot.org/uniprot/Q3SUM1 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS12100 ^@ http://purl.uniprot.org/uniprot/Q3SQ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/323098:NWI_RS01690 ^@ http://purl.uniprot.org/uniprot/Q3SVV1 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/323098:NWI_RS09610 ^@ http://purl.uniprot.org/uniprot/Q3SRI9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS01920 ^@ http://purl.uniprot.org/uniprot/Q3SVQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/323098:NWI_RS03290 ^@ http://purl.uniprot.org/uniprot/Q3SUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/323098:NWI_RS00150 ^@ http://purl.uniprot.org/uniprot/Q3SWP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/323098:NWI_RS00145 ^@ http://purl.uniprot.org/uniprot/Q3SWP7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/323098:NWI_RS03300 ^@ http://purl.uniprot.org/uniprot/Q3SUY8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/323098:NWI_RS13995 ^@ http://purl.uniprot.org/uniprot/Q3SP44 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS01455 ^@ http://purl.uniprot.org/uniprot/Q3SVZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/323098:NWI_RS14215 ^@ http://purl.uniprot.org/uniprot/Q3SP02 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/323098:NWI_RS10920 ^@ http://purl.uniprot.org/uniprot/Q3SQU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS00120 ^@ http://purl.uniprot.org/uniprot/Q3SWQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/323098:NWI_RS06280 ^@ http://purl.uniprot.org/uniprot/Q3STB3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 7 family. http://togogenome.org/gene/323098:NWI_RS06945 ^@ http://purl.uniprot.org/uniprot/Q3SSZ0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS06330 ^@ http://purl.uniprot.org/uniprot/Q3STA4 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS06300 ^@ http://purl.uniprot.org/uniprot/Q3STB0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/323098:NWI_RS08650 ^@ http://purl.uniprot.org/uniprot/Q3SS23 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/323098:NWI_RS03415 ^@ http://purl.uniprot.org/uniprot/Q3SUW7 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS01245 ^@ http://purl.uniprot.org/uniprot/Q3SW35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/323098:NWI_RS14150 ^@ http://purl.uniprot.org/uniprot/Q3SP15 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/323098:NWI_RS09680 ^@ http://purl.uniprot.org/uniprot/Q3SRH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/323098:NWI_RS12590 ^@ http://purl.uniprot.org/uniprot/Q3SPW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS12185 ^@ http://purl.uniprot.org/uniprot/Q3SQ48 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS05470 ^@ http://purl.uniprot.org/uniprot/Q3STR8 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/323098:NWI_RS07510 ^@ http://purl.uniprot.org/uniprot/Q3SSN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/323098:NWI_RS08870 ^@ http://purl.uniprot.org/uniprot/Q3SRX8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/323098:NWI_RS11565 ^@ http://purl.uniprot.org/uniprot/Q3SQG9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/323098:NWI_RS00270 ^@ http://purl.uniprot.org/uniprot/Q3SWM2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/323098:NWI_RS02145 ^@ http://purl.uniprot.org/uniprot/Q3SVL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS07120 ^@ http://purl.uniprot.org/uniprot/Q3SSV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS08105 ^@ http://purl.uniprot.org/uniprot/Q3SSC6 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/323098:NWI_RS13630 ^@ http://purl.uniprot.org/uniprot/Q3SPB4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. PCD1 subfamily. http://togogenome.org/gene/323098:NWI_RS00480 ^@ http://purl.uniprot.org/uniprot/Q3SWI4 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/323098:NWI_RS15030 ^@ http://purl.uniprot.org/uniprot/Q3SNJ9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/323098:NWI_RS13445 ^@ http://purl.uniprot.org/uniprot/Q3SPF1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/323098:NWI_RS05820 ^@ http://purl.uniprot.org/uniprot/Q3STJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/323098:NWI_RS02585 ^@ http://purl.uniprot.org/uniprot/Q3SVC7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/323098:NWI_RS00420 ^@ http://purl.uniprot.org/uniprot/Q3SWJ5 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/323098:NWI_RS11590 ^@ http://purl.uniprot.org/uniprot/Q3SQG4 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/323098:NWI_RS01120 ^@ http://purl.uniprot.org/uniprot/Q3SW60 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS13600 ^@ http://purl.uniprot.org/uniprot/Q3SPC0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/323098:NWI_RS00140 ^@ http://purl.uniprot.org/uniprot/Q3SWP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/323098:NWI_RS05475 ^@ http://purl.uniprot.org/uniprot/Q3STR7 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/323098:NWI_RS10690 ^@ http://purl.uniprot.org/uniprot/Q3SQY2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS08920 ^@ http://purl.uniprot.org/uniprot/Q3SRW8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/323098:NWI_RS02150 ^@ http://purl.uniprot.org/uniprot/Q3SVK9 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS12785 ^@ http://purl.uniprot.org/uniprot/Q3SPT4 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS08660 ^@ http://purl.uniprot.org/uniprot/Q3SS21 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/323098:NWI_RS09840 ^@ http://purl.uniprot.org/uniprot/Q3SRE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS02580 ^@ http://purl.uniprot.org/uniprot/Q3SVC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/323098:NWI_RS10440 ^@ http://purl.uniprot.org/uniprot/Q3SR29 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/323098:NWI_RS08750 ^@ http://purl.uniprot.org/uniprot/Q3SS02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS14570 ^@ http://purl.uniprot.org/uniprot/Q3SNT2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/323098:NWI_RS13490 ^@ http://purl.uniprot.org/uniprot/Q3SPE2 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/323098:NWI_RS10165 ^@ http://purl.uniprot.org/uniprot/Q3SR84 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/323098:NWI_RS01685 ^@ http://purl.uniprot.org/uniprot/Q3SVV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.|||Cell inner membrane|||Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB). http://togogenome.org/gene/323098:NWI_RS02245 ^@ http://purl.uniprot.org/uniprot/Q3SVJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/323098:NWI_RS02630 ^@ http://purl.uniprot.org/uniprot/Q3SVB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/323098:NWI_RS05085 ^@ http://purl.uniprot.org/uniprot/Q3STZ9 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS13955 ^@ http://purl.uniprot.org/uniprot/Q3SP52 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/323098:NWI_RS00305 ^@ http://purl.uniprot.org/uniprot/Q3SWL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/323098:NWI_RS12255 ^@ http://purl.uniprot.org/uniprot/Q3SQ34 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/323098:NWI_RS01915 ^@ http://purl.uniprot.org/uniprot/Q3SVQ7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/323098:NWI_RS14265 ^@ http://purl.uniprot.org/uniprot/Q3SNZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS01180 ^@ http://purl.uniprot.org/uniprot/Q3SUL3|||http://purl.uniprot.org/uniprot/Q3SW48 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/323098:NWI_RS10840 ^@ http://purl.uniprot.org/uniprot/Q3SQV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/323098:NWI_RS04745 ^@ http://purl.uniprot.org/uniprot/Q3SU65 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS09375 ^@ http://purl.uniprot.org/uniprot/Q3SRN5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS11915 ^@ http://purl.uniprot.org/uniprot/Q3SQA1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/323098:NWI_RS06385 ^@ http://purl.uniprot.org/uniprot/Q3ST93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/323098:NWI_RS08295 ^@ http://purl.uniprot.org/uniprot/Q3SS91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/323098:NWI_RS04000 ^@ http://purl.uniprot.org/uniprot/Q3SUK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS02840 ^@ http://purl.uniprot.org/uniprot/Q3SV77 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/323098:NWI_RS06165 ^@ http://purl.uniprot.org/uniprot/Q3STD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell inner membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/323098:NWI_RS10445 ^@ http://purl.uniprot.org/uniprot/Q3SR28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF nuclease family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS05525 ^@ http://purl.uniprot.org/uniprot/Q3STQ7 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/323098:NWI_RS05675 ^@ http://purl.uniprot.org/uniprot/Q3STM7 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/323098:NWI_RS05405 ^@ http://purl.uniprot.org/uniprot/Q3STT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS05750 ^@ http://purl.uniprot.org/uniprot/Q3STL2 ^@ Caution|||Similarity ^@ Belongs to the NTE family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS01205 ^@ http://purl.uniprot.org/uniprot/Q3SW43 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/323098:NWI_RS00800 ^@ http://purl.uniprot.org/uniprot/Q3SWC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08770 ^@ http://purl.uniprot.org/uniprot/Q3SRZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/323098:NWI_RS10550 ^@ http://purl.uniprot.org/uniprot/Q3SR08 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/323098:NWI_RS12095 ^@ http://purl.uniprot.org/uniprot/Q3SQ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.|||Cell inner membrane|||Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (HmuV), two transmembrane proteins (HmuU) and a solute-binding protein (HmuT). http://togogenome.org/gene/323098:NWI_RS08775 ^@ http://purl.uniprot.org/uniprot/Q3SRZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/323098:NWI_RS09705 ^@ http://purl.uniprot.org/uniprot/Q3SRG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/323098:NWI_RS14135 ^@ http://purl.uniprot.org/uniprot/Q3SP18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/323098:NWI_RS01470 ^@ http://purl.uniprot.org/uniprot/Q3SVZ5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/323098:NWI_RS06560 ^@ http://purl.uniprot.org/uniprot/Q3SQ81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/323098:NWI_RS02235 ^@ http://purl.uniprot.org/uniprot/Q3SVJ2 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/323098:NWI_RS10800 ^@ http://purl.uniprot.org/uniprot/Q3SQW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS09655 ^@ http://purl.uniprot.org/uniprot/Q3SRI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/323098:NWI_RS08700 ^@ http://purl.uniprot.org/uniprot/Q3SS13 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/323098:NWI_RS09205 ^@ http://purl.uniprot.org/uniprot/Q3SRR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02260 ^@ http://purl.uniprot.org/uniprot/Q3SVI8 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/323098:NWI_RS13255 ^@ http://purl.uniprot.org/uniprot/Q3SPJ0 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/323098:NWI_RS11150 ^@ http://purl.uniprot.org/uniprot/Q3SQP9 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/323098:NWI_RS14000 ^@ http://purl.uniprot.org/uniprot/Q3SP43 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS12000 ^@ http://purl.uniprot.org/uniprot/Q3SQ84 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS11445 ^@ http://purl.uniprot.org/uniprot/Q3SQJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS13155 ^@ http://purl.uniprot.org/uniprot/Q3SPK9 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/323098:NWI_RS04805 ^@ http://purl.uniprot.org/uniprot/Q3SU53 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/323098:NWI_RS05365 ^@ http://purl.uniprot.org/uniprot/Q3STT9 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/323098:NWI_RS12415 ^@ http://purl.uniprot.org/uniprot/Q3SQ00 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/323098:NWI_RS13590 ^@ http://purl.uniprot.org/uniprot/Q3SPC2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 1 heme c group covalently per subunit.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||Mitochondrion inner membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/323098:NWI_RS12190 ^@ http://purl.uniprot.org/uniprot/Q3SQ47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||In the C-terminal section; belongs to the OsmX family.|||In the N-terminal section; belongs to the binding-protein-dependent transport system permease family. http://togogenome.org/gene/323098:NWI_RS14205 ^@ http://purl.uniprot.org/uniprot/Q3SP04 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS05840 ^@ http://purl.uniprot.org/uniprot/Q3STJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/323098:NWI_RS08790 ^@ http://purl.uniprot.org/uniprot/Q3SRZ4 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/323098:NWI_RS02570 ^@ http://purl.uniprot.org/uniprot/Q3SVD0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/323098:NWI_RS07050 ^@ http://purl.uniprot.org/uniprot/Q3SSX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/323098:NWI_RS15600 ^@ http://purl.uniprot.org/uniprot/Q3SN93 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/323098:NWI_RS07960 ^@ http://purl.uniprot.org/uniprot/Q3SSF1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/323098:NWI_RS13470 ^@ http://purl.uniprot.org/uniprot/Q3SPE6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/323098:NWI_RS03220 ^@ http://purl.uniprot.org/uniprot/Q3SV05 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS10215 ^@ http://purl.uniprot.org/uniprot/Q3SR74 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/323098:NWI_RS04960 ^@ http://purl.uniprot.org/uniprot/Q3SU22 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS00885 ^@ http://purl.uniprot.org/uniprot/Q3SWA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/323098:NWI_RS10610 ^@ http://purl.uniprot.org/uniprot/Q3SQZ7 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS09110 ^@ http://purl.uniprot.org/uniprot/Q3SRT5 ^@ Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. http://togogenome.org/gene/323098:NWI_RS11405 ^@ http://purl.uniprot.org/uniprot/Q3SQK0 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/323098:NWI_RS12765 ^@ http://purl.uniprot.org/uniprot/Q3SPT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/323098:NWI_RS13115 ^@ http://purl.uniprot.org/uniprot/Q3SPL7 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/323098:NWI_RS04820 ^@ http://purl.uniprot.org/uniprot/Q3SU50 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/323098:NWI_RS03205 ^@ http://purl.uniprot.org/uniprot/Q3SV08 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/323098:NWI_RS13135 ^@ http://purl.uniprot.org/uniprot/Q3SPL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/323098:NWI_RS08245 ^@ http://purl.uniprot.org/uniprot/Q3SSA2 ^@ Similarity ^@ Belongs to the thioester dehydratase family. FabA subfamily. http://togogenome.org/gene/323098:NWI_RS06995 ^@ http://purl.uniprot.org/uniprot/Q3SSY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/323098:NWI_RS05410 ^@ http://purl.uniprot.org/uniprot/Q3STT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS00020 ^@ http://purl.uniprot.org/uniprot/Q3SMU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/323098:NWI_RS11195 ^@ http://purl.uniprot.org/uniprot/Q3SQP1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/323098:NWI_RS05380 ^@ http://purl.uniprot.org/uniprot/Q3STT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/323098:NWI_RS03955 ^@ http://purl.uniprot.org/uniprot/Q3SUL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/323098:NWI_RS12885 ^@ http://purl.uniprot.org/uniprot/Q3SPR3 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/323098:NWI_RS10020 ^@ http://purl.uniprot.org/uniprot/Q3SRB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/323098:NWI_RS06365 ^@ http://purl.uniprot.org/uniprot/Q3ST97 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/323098:NWI_RS00870 ^@ http://purl.uniprot.org/uniprot/Q3SWA8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS09930 ^@ http://purl.uniprot.org/uniprot/Q3SRC9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS08910 ^@ http://purl.uniprot.org/uniprot/Q3SRX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide deacetylase family.|||Cytoplasm|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/323098:NWI_RS00215 ^@ http://purl.uniprot.org/uniprot/Q3SWN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/323098:NWI_RS14450 ^@ http://purl.uniprot.org/uniprot/Q3SNV5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/323098:NWI_RS05415 ^@ http://purl.uniprot.org/uniprot/Q3STS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS08605 ^@ http://purl.uniprot.org/uniprot/Q3SS32 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/323098:NWI_RS14045 ^@ http://purl.uniprot.org/uniprot/Q3SP35 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/323098:NWI_RS13550 ^@ http://purl.uniprot.org/uniprot/Q3SPD0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/323098:NWI_RS09910 ^@ http://purl.uniprot.org/uniprot/Q3SRD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/323098:NWI_RS03185 ^@ http://purl.uniprot.org/uniprot/Q3SV13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS14510 ^@ http://purl.uniprot.org/uniprot/Q3SNU3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS05200 ^@ http://purl.uniprot.org/uniprot/Q3STX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/323098:NWI_RS10135 ^@ http://purl.uniprot.org/uniprot/Q3SR90 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/323098:NWI_RS07445 ^@ http://purl.uniprot.org/uniprot/Q3SSP4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/323098:NWI_RS01860 ^@ http://purl.uniprot.org/uniprot/Q3SVR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/323098:NWI_RS12935 ^@ http://purl.uniprot.org/uniprot/Q3SPQ3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/323098:NWI_RS14530 ^@ http://purl.uniprot.org/uniprot/Q3SNT9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/323098:NWI_RS00620 ^@ http://purl.uniprot.org/uniprot/Q3SWF6 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/323098:NWI_RS14430 ^@ http://purl.uniprot.org/uniprot/Q3SNV9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/323098:NWI_RS07885 ^@ http://purl.uniprot.org/uniprot/Q3SSG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RecG subfamily.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS14495 ^@ http://purl.uniprot.org/uniprot/Q3SNU6 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/323098:NWI_RS14580 ^@ http://purl.uniprot.org/uniprot/Q3SNT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS08630 ^@ http://purl.uniprot.org/uniprot/Q3SS27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/323098:NWI_RS09545 ^@ http://purl.uniprot.org/uniprot/Q3SRK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS09915 ^@ http://purl.uniprot.org/uniprot/Q3SRD1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/323098:NWI_RS07165 ^@ http://purl.uniprot.org/uniprot/Q3SSU8 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS13475 ^@ http://purl.uniprot.org/uniprot/Q3SPE5 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/323098:NWI_RS10630 ^@ http://purl.uniprot.org/uniprot/Q3SQZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/323098:NWI_RS04465 ^@ http://purl.uniprot.org/uniprot/Q3SUB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrbI/VirB10 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS09035 ^@ http://purl.uniprot.org/uniprot/Q3SRU9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/323098:NWI_RS05205 ^@ http://purl.uniprot.org/uniprot/Q3STX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/323098:NWI_RS08740 ^@ http://purl.uniprot.org/uniprot/Q3SS04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/323098:NWI_RS01300 ^@ http://purl.uniprot.org/uniprot/Q3SW25 ^@ Similarity ^@ Belongs to the UPF0262 family. http://togogenome.org/gene/323098:NWI_RS07460 ^@ http://purl.uniprot.org/uniprot/Q3SSP1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02825 ^@ http://purl.uniprot.org/uniprot/Q3SV80 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/323098:NWI_RS03080 ^@ http://purl.uniprot.org/uniprot/Q3SV33 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/323098:NWI_RS00485 ^@ http://purl.uniprot.org/uniprot/Q3SWI3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/323098:NWI_RS07065 ^@ http://purl.uniprot.org/uniprot/Q3SSW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/323098:NWI_RS02215 ^@ http://purl.uniprot.org/uniprot/Q3SVJ6 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/323098:NWI_RS16365 ^@ http://purl.uniprot.org/uniprot/Q3SW06 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/323098:NWI_RS01055 ^@ http://purl.uniprot.org/uniprot/Q3SW71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS10370 ^@ http://purl.uniprot.org/uniprot/Q3SR43 ^@ Function|||Subunit ^@ Homotrimer.|||In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. http://togogenome.org/gene/323098:NWI_RS00655 ^@ http://purl.uniprot.org/uniprot/Q3SWE9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR. http://togogenome.org/gene/323098:NWI_RS14435 ^@ http://purl.uniprot.org/uniprot/Q3SNV8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/323098:NWI_RS08985 ^@ http://purl.uniprot.org/uniprot/Q3SRV7 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/323098:NWI_RS08590 ^@ http://purl.uniprot.org/uniprot/Q3SS35 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/323098:NWI_RS03465 ^@ http://purl.uniprot.org/uniprot/Q3SUV7 ^@ Function ^@ Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS08210 ^@ http://purl.uniprot.org/uniprot/Q3SSA9 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/323098:NWI_RS09150 ^@ http://purl.uniprot.org/uniprot/Q3SRS7 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/323098:NWI_RS09785 ^@ http://purl.uniprot.org/uniprot/Q3SRF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS12380 ^@ http://purl.uniprot.org/uniprot/Q3SQ07 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS09005 ^@ http://purl.uniprot.org/uniprot/Q3SRV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS15820 ^@ http://purl.uniprot.org/uniprot/Q3SN51 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/323098:NWI_RS03040 ^@ http://purl.uniprot.org/uniprot/Q3SV41 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS08060 ^@ http://purl.uniprot.org/uniprot/Q3SSD4 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/323098:NWI_RS03885 ^@ http://purl.uniprot.org/uniprot/Q3SUM8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/323098:NWI_RS00860 ^@ http://purl.uniprot.org/uniprot/Q3SWB0 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/323098:NWI_RS01670 ^@ http://purl.uniprot.org/uniprot/Q3SVV5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/323098:NWI_RS12290 ^@ http://purl.uniprot.org/uniprot/Q3SQ27 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/323098:NWI_RS00200 ^@ http://purl.uniprot.org/uniprot/Q3SWN6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS10475 ^@ http://purl.uniprot.org/uniprot/Q3SR22 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/323098:NWI_RS07125 ^@ http://purl.uniprot.org/uniprot/Q3SSV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/323098:NWI_RS07505 ^@ http://purl.uniprot.org/uniprot/Q3SSN2 ^@ Function ^@ Acts on leucine, isoleucine and valine. http://togogenome.org/gene/323098:NWI_RS02440 ^@ http://purl.uniprot.org/uniprot/Q3SVF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08975 ^@ http://purl.uniprot.org/uniprot/Q3SRV9 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/323098:NWI_RS12300 ^@ http://purl.uniprot.org/uniprot/Q3SQ25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07990 ^@ http://purl.uniprot.org/uniprot/Q3SSE5 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/323098:NWI_RS12365 ^@ http://purl.uniprot.org/uniprot/Q3SQ10 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/323098:NWI_RS06195 ^@ http://purl.uniprot.org/uniprot/Q3STD0 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/323098:NWI_RS15215 ^@ http://purl.uniprot.org/uniprot/Q3SNG4 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/323098:NWI_RS14240 ^@ http://purl.uniprot.org/uniprot/Q3SNZ7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS07090 ^@ http://purl.uniprot.org/uniprot/Q3SSW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/323098:NWI_RS13485 ^@ http://purl.uniprot.org/uniprot/Q3SPE3 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/323098:NWI_RS00450 ^@ http://purl.uniprot.org/uniprot/Q3SWJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/323098:NWI_RS09965 ^@ http://purl.uniprot.org/uniprot/Q3SRC2 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/323098:NWI_RS03905 ^@ http://purl.uniprot.org/uniprot/Q3SUM4 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/323098:NWI_RS07930 ^@ http://purl.uniprot.org/uniprot/Q3SSF7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/323098:NWI_RS11425 ^@ http://purl.uniprot.org/uniprot/Q3SQJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/323098:NWI_RS10345 ^@ http://purl.uniprot.org/uniprot/Q3SR48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.|||Carboxysome http://togogenome.org/gene/323098:NWI_RS05105 ^@ http://purl.uniprot.org/uniprot/Q3STZ3 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/323098:NWI_RS08595 ^@ http://purl.uniprot.org/uniprot/Q3SS34 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/323098:NWI_RS09800 ^@ http://purl.uniprot.org/uniprot/Q3SRF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/323098:NWI_RS15355 ^@ http://purl.uniprot.org/uniprot/Q3SND9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS13960 ^@ http://purl.uniprot.org/uniprot/Q3SP51 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/323098:NWI_RS08820 ^@ http://purl.uniprot.org/uniprot/Q3SRY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/323098:NWI_RS13195 ^@ http://purl.uniprot.org/uniprot/Q3SPK1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/323098:NWI_RS01110 ^@ http://purl.uniprot.org/uniprot/Q3SW62 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS14440 ^@ http://purl.uniprot.org/uniprot/Q3SNV7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/323098:NWI_RS16345 ^@ http://purl.uniprot.org/uniprot/Q3SMV1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/323098:NWI_RS06625 ^@ http://purl.uniprot.org/uniprot/Q3ST50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS14630 ^@ http://purl.uniprot.org/uniprot/Q3SNS1 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs. http://togogenome.org/gene/323098:NWI_RS09870 ^@ http://purl.uniprot.org/uniprot/Q3SRD8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/323098:NWI_RS07590 ^@ http://purl.uniprot.org/uniprot/Q3SSL6 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/323098:NWI_RS02500 ^@ http://purl.uniprot.org/uniprot/Q3SVE5 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/323098:NWI_RS16125 ^@ http://purl.uniprot.org/uniprot/Q3SMZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/323098:NWI_RS09275 ^@ http://purl.uniprot.org/uniprot/Q3SRQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/323098:NWI_RS05490 ^@ http://purl.uniprot.org/uniprot/Q3STR4 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS00505 ^@ http://purl.uniprot.org/uniprot/Q3SWH9 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/323098:NWI_RS00700 ^@ http://purl.uniprot.org/uniprot/Q3SWE0 ^@ Activity Regulation|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/323098:NWI_RS16255 ^@ http://purl.uniprot.org/uniprot/Q3SMW4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/323098:NWI_RS01530 ^@ http://purl.uniprot.org/uniprot/Q3SVY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/323098:NWI_RS09830 ^@ http://purl.uniprot.org/uniprot/Q3SRE5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS04645 ^@ http://purl.uniprot.org/uniprot/Q3SU83 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS11690 ^@ http://purl.uniprot.org/uniprot/Q3SQE6 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/323098:NWI_RS02415 ^@ http://purl.uniprot.org/uniprot/Q3SVG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/323098:NWI_RS03540 ^@ http://purl.uniprot.org/uniprot/Q3SUU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/323098:NWI_RS02125 ^@ http://purl.uniprot.org/uniprot/Q3SVL3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/323098:NWI_RS04225 ^@ http://purl.uniprot.org/uniprot/Q3SUG1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/323098:NWI_RS13125 ^@ http://purl.uniprot.org/uniprot/Q3SPL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaE family.|||Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/323098:NWI_RS12310 ^@ http://purl.uniprot.org/uniprot/Q3SQ23 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS15285 ^@ http://purl.uniprot.org/uniprot/Q3SNF1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS14540 ^@ http://purl.uniprot.org/uniprot/Q3SNT7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/323098:NWI_RS00360 ^@ http://purl.uniprot.org/uniprot/Q3SWK5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/323098:NWI_RS01765 ^@ http://purl.uniprot.org/uniprot/Q3SVT6 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS11520 ^@ http://purl.uniprot.org/uniprot/Q3SQH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS04795 ^@ http://purl.uniprot.org/uniprot/Q3SU55 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/323098:NWI_RS11025 ^@ http://purl.uniprot.org/uniprot/Q3SQS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/323098:NWI_RS05425 ^@ http://purl.uniprot.org/uniprot/Q3STS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02360 ^@ http://purl.uniprot.org/uniprot/Q3SVH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS14160 ^@ http://purl.uniprot.org/uniprot/Q3SP13 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/323098:NWI_RS11530 ^@ http://purl.uniprot.org/uniprot/Q3SQH6 ^@ Function ^@ Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS15945 ^@ http://purl.uniprot.org/uniprot/Q3SN30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS02385 ^@ http://purl.uniprot.org/uniprot/Q3SVG6 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS07410 ^@ http://purl.uniprot.org/uniprot/Q3SSQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/323098:NWI_RS14500 ^@ http://purl.uniprot.org/uniprot/Q3SNU5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS04720 ^@ http://purl.uniprot.org/uniprot/Q3SU69 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/323098:NWI_RS08680 ^@ http://purl.uniprot.org/uniprot/Q3SS17 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS04825 ^@ http://purl.uniprot.org/uniprot/Q3SU49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS14970 ^@ http://purl.uniprot.org/uniprot/Q3SNL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07455 ^@ http://purl.uniprot.org/uniprot/Q3SSP2 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/323098:NWI_RS02160 ^@ http://purl.uniprot.org/uniprot/Q3SVK7 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/323098:NWI_RS12210 ^@ http://purl.uniprot.org/uniprot/Q3SQ43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Monomer. http://togogenome.org/gene/323098:NWI_RS12910 ^@ http://purl.uniprot.org/uniprot/Q3SPQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS15125 ^@ http://purl.uniprot.org/uniprot/Q3SNH9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/323098:NWI_RS00835 ^@ http://purl.uniprot.org/uniprot/Q3SWB5 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/323098:NWI_RS10530 ^@ http://purl.uniprot.org/uniprot/Q3SR12 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/323098:NWI_RS14595 ^@ http://purl.uniprot.org/uniprot/Q3SNS8 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/323098:NWI_RS09630 ^@ http://purl.uniprot.org/uniprot/Q3SRI5 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/323098:NWI_RS11385 ^@ http://purl.uniprot.org/uniprot/Q3SQK3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/323098:NWI_RS01505 ^@ http://purl.uniprot.org/uniprot/Q3SVY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS05785 ^@ http://purl.uniprot.org/uniprot/Q3STK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/323098:NWI_RS09585 ^@ http://purl.uniprot.org/uniprot/Q3SRJ3 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/323098:NWI_RS13370 ^@ http://purl.uniprot.org/uniprot/Q3SPG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CheZ family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS09900 ^@ http://purl.uniprot.org/uniprot/Q3SRD4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/323098:NWI_RS14180 ^@ http://purl.uniprot.org/uniprot/Q3SP09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02445 ^@ http://purl.uniprot.org/uniprot/Q3SVF4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/323098:NWI_RS11750 ^@ http://purl.uniprot.org/uniprot/Q3SQD3 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/323098:NWI_RS10455 ^@ http://purl.uniprot.org/uniprot/Q3SR26 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS07140 ^@ http://purl.uniprot.org/uniprot/Q3SSV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/323098:NWI_RS03995 ^@ http://purl.uniprot.org/uniprot/Q3SUK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS08795 ^@ http://purl.uniprot.org/uniprot/Q3SRZ3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS12700 ^@ http://purl.uniprot.org/uniprot/Q3SPU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/323098:NWI_RS12390 ^@ http://purl.uniprot.org/uniprot/Q3SQ05 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/323098:NWI_RS08925 ^@ http://purl.uniprot.org/uniprot/Q3SRW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS09675 ^@ http://purl.uniprot.org/uniprot/Q3SRH6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS09975 ^@ http://purl.uniprot.org/uniprot/Q3SRC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/323098:NWI_RS09660 ^@ http://purl.uniprot.org/uniprot/Q3SRH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/323098:NWI_RS01595 ^@ http://purl.uniprot.org/uniprot/Q3SVX1 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/323098:NWI_RS02015 ^@ http://purl.uniprot.org/uniprot/Q3SVN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS11540 ^@ http://purl.uniprot.org/uniprot/Q3SQH4 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/323098:NWI_RS06220 ^@ http://purl.uniprot.org/uniprot/Q3STC5 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/323098:NWI_RS02820 ^@ http://purl.uniprot.org/uniprot/Q3SV81 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS03990 ^@ http://purl.uniprot.org/uniprot/Q3SUK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS00665 ^@ http://purl.uniprot.org/uniprot/Q3SWE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS00565 ^@ http://purl.uniprot.org/uniprot/Q3SWG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/323098:NWI_RS15705 ^@ http://purl.uniprot.org/uniprot/Q3SN74 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS14320 ^@ http://purl.uniprot.org/uniprot/Q3SNY1 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS14395 ^@ http://purl.uniprot.org/uniprot/Q3SNW5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS04115 ^@ http://purl.uniprot.org/uniprot/Q3SUI2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/323098:NWI_RS02050 ^@ http://purl.uniprot.org/uniprot/Q3SVM8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02175 ^@ http://purl.uniprot.org/uniprot/Q3SVK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/323098:NWI_RS03230 ^@ http://purl.uniprot.org/uniprot/Q3SV02 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/323098:NWI_RS06980 ^@ http://purl.uniprot.org/uniprot/Q3SSY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/323098:NWI_RS02020 ^@ http://purl.uniprot.org/uniprot/Q3SVN4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||May bind 1 zinc ion per subunit.|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/323098:NWI_RS09905 ^@ http://purl.uniprot.org/uniprot/Q3SRD3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/323098:NWI_RS09380 ^@ http://purl.uniprot.org/uniprot/Q3SRN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/323098:NWI_RS05605 ^@ http://purl.uniprot.org/uniprot/Q3STP1 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/323098:NWI_RS15225 ^@ http://purl.uniprot.org/uniprot/Q3SNG2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the RuBisCO large chain family. Type I subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterohexadecamer of 8 large chains and 8 small chains.|||RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.|||The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'. http://togogenome.org/gene/323098:NWI_RS15400 ^@ http://purl.uniprot.org/uniprot/Q3SND1 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/323098:NWI_RS03200 ^@ http://purl.uniprot.org/uniprot/Q3SV09 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS08765 ^@ http://purl.uniprot.org/uniprot/Q3SRZ9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/323098:NWI_RS11710 ^@ http://purl.uniprot.org/uniprot/Q3SQE2 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/323098:NWI_RS05740 ^@ http://purl.uniprot.org/uniprot/Q3STL4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS07560 ^@ http://purl.uniprot.org/uniprot/Q3SSM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS13335 ^@ http://purl.uniprot.org/uniprot/Q3SPH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS07055 ^@ http://purl.uniprot.org/uniprot/Q3SSX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/323098:NWI_RS03640 ^@ http://purl.uniprot.org/uniprot/Q3SUS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/323098:NWI_RS06235 ^@ http://purl.uniprot.org/uniprot/Q3STC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/323098:NWI_RS05770 ^@ http://purl.uniprot.org/uniprot/Q3STK8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/323098:NWI_RS00285 ^@ http://purl.uniprot.org/uniprot/Q3SWL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/323098:NWI_RS12915 ^@ http://purl.uniprot.org/uniprot/Q3SPQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. Tam family.|||Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS09595 ^@ http://purl.uniprot.org/uniprot/Q3SRJ1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/323098:NWI_RS03625 ^@ http://purl.uniprot.org/uniprot/Q3SUS4 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/323098:NWI_RS15120 ^@ http://purl.uniprot.org/uniprot/Q3SNI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS10640 ^@ http://purl.uniprot.org/uniprot/Q3SQZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.|||Cell inner membrane|||Homodimer.|||Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. http://togogenome.org/gene/323098:NWI_RS12295 ^@ http://purl.uniprot.org/uniprot/Q3SQ26 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS08345 ^@ http://purl.uniprot.org/uniprot/Q3SS81 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/323098:NWI_RS12015 ^@ http://purl.uniprot.org/uniprot/Q3SQ81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/323098:NWI_RS14235 ^@ http://purl.uniprot.org/uniprot/Q3SNZ8 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/323098:NWI_RS14010 ^@ http://purl.uniprot.org/uniprot/Q3SP42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/323098:NWI_RS09535 ^@ http://purl.uniprot.org/uniprot/Q3SRK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02830 ^@ http://purl.uniprot.org/uniprot/Q3SV79 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/323098:NWI_RS00625 ^@ http://purl.uniprot.org/uniprot/Q3SWF5 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/323098:NWI_RS09970 ^@ http://purl.uniprot.org/uniprot/Q3SRC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS10565 ^@ http://purl.uniprot.org/uniprot/Q3SR05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/323098:NWI_RS09390 ^@ http://purl.uniprot.org/uniprot/Q3SRN2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/323098:NWI_RS00955 ^@ http://purl.uniprot.org/uniprot/Q3SW91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.|||Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).|||Homodimer or monomer when oxidized or reduced, respectively.|||chloroplast http://togogenome.org/gene/323098:NWI_RS05075 ^@ http://purl.uniprot.org/uniprot/Q3SU01 ^@ Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer. http://togogenome.org/gene/323098:NWI_RS13615 ^@ http://purl.uniprot.org/uniprot/Q3SPB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/323098:NWI_RS07465 ^@ http://purl.uniprot.org/uniprot/Q3SSP0 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/323098:NWI_RS06360 ^@ http://purl.uniprot.org/uniprot/Q3ST98 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/323098:NWI_RS10085 ^@ http://purl.uniprot.org/uniprot/Q3SR98 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alphaproteobacteria porin family.|||Cell outer membrane|||Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.|||Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane. http://togogenome.org/gene/323098:NWI_RS15995 ^@ http://purl.uniprot.org/uniprot/Q3SN20 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/323098:NWI_RS13710 ^@ http://purl.uniprot.org/uniprot/Q3SP99 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/323098:NWI_RS05485 ^@ http://purl.uniprot.org/uniprot/Q3STR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS14270 ^@ http://purl.uniprot.org/uniprot/Q3SNZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS02140 ^@ http://purl.uniprot.org/uniprot/Q3SVL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS01005 ^@ http://purl.uniprot.org/uniprot/Q3SW81 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/323098:NWI_RS06650 ^@ http://purl.uniprot.org/uniprot/Q3ST44 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/323098:NWI_RS06370 ^@ http://purl.uniprot.org/uniprot/Q3ST96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS08745 ^@ http://purl.uniprot.org/uniprot/Q3SS03 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS13805 ^@ http://purl.uniprot.org/uniprot/Q3SP80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07190 ^@ http://purl.uniprot.org/uniprot/Q3SSU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/323098:NWI_RS04990 ^@ http://purl.uniprot.org/uniprot/Q3SU16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS14175 ^@ http://purl.uniprot.org/uniprot/Q3SP10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS09385 ^@ http://purl.uniprot.org/uniprot/Q3SRN3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/323098:NWI_RS06655 ^@ http://purl.uniprot.org/uniprot/Q3ST43 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08830 ^@ http://purl.uniprot.org/uniprot/Q3SRY6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/323098:NWI_RS13575 ^@ http://purl.uniprot.org/uniprot/Q3SPC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS05130 ^@ http://purl.uniprot.org/uniprot/Q3STY8 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS10015 ^@ http://purl.uniprot.org/uniprot/Q3SRB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS04445 ^@ http://purl.uniprot.org/uniprot/Q3SUC1 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/323098:NWI_RS00545 ^@ http://purl.uniprot.org/uniprot/Q3SWH1 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/323098:NWI_RS11905 ^@ http://purl.uniprot.org/uniprot/Q3SQA3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/323098:NWI_RS13020 ^@ http://purl.uniprot.org/uniprot/Q3SPN6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/323098:NWI_RS02290 ^@ http://purl.uniprot.org/uniprot/Q3SVI4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/323098:NWI_RS13410 ^@ http://purl.uniprot.org/uniprot/Q3SPF9 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/323098:NWI_RS01710 ^@ http://purl.uniprot.org/uniprot/Q3SVU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS04735 ^@ http://purl.uniprot.org/uniprot/Q3SU66 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/323098:NWI_RS02240 ^@ http://purl.uniprot.org/uniprot/Q3SVJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/323098:NWI_RS06290 ^@ http://purl.uniprot.org/uniprot/Q3STB2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/323098:NWI_RS00230 ^@ http://purl.uniprot.org/uniprot/Q3SWN0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS14210 ^@ http://purl.uniprot.org/uniprot/Q3SP03 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS07425 ^@ http://purl.uniprot.org/uniprot/Q3SSP8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS08800 ^@ http://purl.uniprot.org/uniprot/Q3SRZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS07495 ^@ http://purl.uniprot.org/uniprot/Q3SSN4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS09435 ^@ http://purl.uniprot.org/uniprot/Q3SRM3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS13110 ^@ http://purl.uniprot.org/uniprot/Q3SPL8 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/323098:NWI_RS09260 ^@ http://purl.uniprot.org/uniprot/Q3SRQ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/323098:NWI_RS15960 ^@ http://purl.uniprot.org/uniprot/Q3SN27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS06170 ^@ http://purl.uniprot.org/uniprot/Q3STD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS13565 ^@ http://purl.uniprot.org/uniprot/Q3SPC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/323098:NWI_RS07135 ^@ http://purl.uniprot.org/uniprot/Q3SSV4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/323098:NWI_RS01680 ^@ http://purl.uniprot.org/uniprot/Q3SVV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/323098:NWI_RS07010 ^@ http://purl.uniprot.org/uniprot/Q3SSY0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/323098:NWI_RS02730 ^@ http://purl.uniprot.org/uniprot/Q3SV98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cytoplasm|||Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. http://togogenome.org/gene/323098:NWI_RS09600 ^@ http://purl.uniprot.org/uniprot/Q3SRJ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/323098:NWI_RS08285 ^@ http://purl.uniprot.org/uniprot/Q3SS93 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/323098:NWI_RS11030 ^@ http://purl.uniprot.org/uniprot/Q3SQS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/323098:NWI_RS12195 ^@ http://purl.uniprot.org/uniprot/Q3SQ46 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. http://togogenome.org/gene/323098:NWI_RS00290 ^@ http://purl.uniprot.org/uniprot/Q3SWL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/323098:NWI_RS15720 ^@ http://purl.uniprot.org/uniprot/Q3SN71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0283 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS02070 ^@ http://purl.uniprot.org/uniprot/Q3SVM4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/323098:NWI_RS14340 ^@ http://purl.uniprot.org/uniprot/Q3SNX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS01175 ^@ http://purl.uniprot.org/uniprot/Q3SUL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/323098:NWI_RS05540 ^@ http://purl.uniprot.org/uniprot/Q3STQ4 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/323098:NWI_RS05660 ^@ http://purl.uniprot.org/uniprot/Q3STN0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/323098:NWI_RS02505 ^@ http://purl.uniprot.org/uniprot/Q3SVE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS07115 ^@ http://purl.uniprot.org/uniprot/Q3SSV8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/323098:NWI_RS12730 ^@ http://purl.uniprot.org/uniprot/Q3SPU1 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/323098:NWI_RS06275 ^@ http://purl.uniprot.org/uniprot/Q3STB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/323098:NWI_RS10055 ^@ http://purl.uniprot.org/uniprot/Q3SRA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/323098:NWI_RS07215 ^@ http://purl.uniprot.org/uniprot/Q3SST8 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/323098:NWI_RS11755 ^@ http://purl.uniprot.org/uniprot/Q3SQD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/323098:NWI_RS00850 ^@ http://purl.uniprot.org/uniprot/Q3SWB2 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/323098:NWI_RS09145 ^@ http://purl.uniprot.org/uniprot/Q3SRS8 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/323098:NWI_RS13795 ^@ http://purl.uniprot.org/uniprot/Q3SP82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS06215 ^@ http://purl.uniprot.org/uniprot/Q3STC6 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/323098:NWI_RS00610 ^@ http://purl.uniprot.org/uniprot/Q3SWF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS05835 ^@ http://purl.uniprot.org/uniprot/Q3STJ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/323098:NWI_RS08340 ^@ http://purl.uniprot.org/uniprot/Q3SS82 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS03170 ^@ http://purl.uniprot.org/uniprot/Q3SV16 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS09250 ^@ http://purl.uniprot.org/uniprot/Q3SRQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS09075 ^@ http://purl.uniprot.org/uniprot/Q3SRU1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/323098:NWI_RS15990 ^@ http://purl.uniprot.org/uniprot/Q3SN21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS08815 ^@ http://purl.uniprot.org/uniprot/Q3SRY9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with bS18 to 16S ribosomal RNA. http://togogenome.org/gene/323098:NWI_RS02650 ^@ http://purl.uniprot.org/uniprot/Q3SVB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/323098:NWI_RS14585 ^@ http://purl.uniprot.org/uniprot/Q3SNS9 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/323098:NWI_RS03630 ^@ http://purl.uniprot.org/uniprot/Q3SUS3 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS11615 ^@ http://purl.uniprot.org/uniprot/Q3SQG0 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/323098:NWI_RS16275 ^@ http://purl.uniprot.org/uniprot/Q3SMW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS02345 ^@ http://purl.uniprot.org/uniprot/Q3SVH3 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/323098:NWI_RS01830 ^@ http://purl.uniprot.org/uniprot/Q3SVS3 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/323098:NWI_RS09570 ^@ http://purl.uniprot.org/uniprot/Q3SRJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/323098:NWI_RS13985 ^@ http://purl.uniprot.org/uniprot/Q3SP46 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/323098:NWI_RS00520 ^@ http://purl.uniprot.org/uniprot/Q3SWH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/323098:NWI_RS11800 ^@ http://purl.uniprot.org/uniprot/Q3SQC4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/323098:NWI_RS14825 ^@ http://purl.uniprot.org/uniprot/Q3SNN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/323098:NWI_RS10615 ^@ http://purl.uniprot.org/uniprot/Q3SQZ6 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/323098:NWI_RS04295 ^@ http://purl.uniprot.org/uniprot/Q3SUE7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/323098:NWI_RS09650 ^@ http://purl.uniprot.org/uniprot/Q3SRI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/323098:NWI_RS07845 ^@ http://purl.uniprot.org/uniprot/Q3SSH3 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/323098:NWI_RS07130 ^@ http://purl.uniprot.org/uniprot/Q3SSV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS09615 ^@ http://purl.uniprot.org/uniprot/Q3SRI8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS08045 ^@ http://purl.uniprot.org/uniprot/Q3SSD7 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/323098:NWI_RS03250 ^@ http://purl.uniprot.org/uniprot/Q3SUZ8 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/323098:NWI_RS02035 ^@ http://purl.uniprot.org/uniprot/Q3SVN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/323098:NWI_RS04455 ^@ http://purl.uniprot.org/uniprot/Q3SUB9 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/323098:NWI_RS15905 ^@ http://purl.uniprot.org/uniprot/Q3SN37 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/323098:NWI_RS09995 ^@ http://purl.uniprot.org/uniprot/Q3SRB6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/323098:NWI_RS09590 ^@ http://purl.uniprot.org/uniprot/Q3SRJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/323098:NWI_RS03340 ^@ http://purl.uniprot.org/uniprot/Q3SUY1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/323098:NWI_RS09810 ^@ http://purl.uniprot.org/uniprot/Q3SRE9 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/323098:NWI_RS10405 ^@ http://purl.uniprot.org/uniprot/Q3SR35 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/323098:NWI_RS03470 ^@ http://purl.uniprot.org/uniprot/Q3SUV6 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS14515 ^@ http://purl.uniprot.org/uniprot/Q3SNU2 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/323098:NWI_RS11430 ^@ http://purl.uniprot.org/uniprot/Q3SQJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/323098:NWI_RS00525 ^@ http://purl.uniprot.org/uniprot/Q3SWH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/323098:NWI_RS12610 ^@ http://purl.uniprot.org/uniprot/Q3SPW3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS08275 ^@ http://purl.uniprot.org/uniprot/Q3SS95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide deacetylase family.|||Cytoplasm|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/323098:NWI_RS16235 ^@ http://purl.uniprot.org/uniprot/Q3SMW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07200 ^@ http://purl.uniprot.org/uniprot/Q3SSU1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/323098:NWI_RS01000 ^@ http://purl.uniprot.org/uniprot/Q3SW82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/323098:NWI_RS12435 ^@ http://purl.uniprot.org/uniprot/Q3SPZ6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR. http://togogenome.org/gene/323098:NWI_RS02310 ^@ http://purl.uniprot.org/uniprot/Q3SVI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS02735 ^@ http://purl.uniprot.org/uniprot/Q3SV97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS12240 ^@ http://purl.uniprot.org/uniprot/Q3SQ37 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/323098:NWI_RS01790 ^@ http://purl.uniprot.org/uniprot/Q3SVT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/323098:NWI_RS09140 ^@ http://purl.uniprot.org/uniprot/Q3SRS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/323098:NWI_RS12760 ^@ http://purl.uniprot.org/uniprot/Q3SPT8 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/323098:NWI_RS15640 ^@ http://purl.uniprot.org/uniprot/Q3SN85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS09550 ^@ http://purl.uniprot.org/uniprot/Q3SRK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS09070 ^@ http://purl.uniprot.org/uniprot/Q3SRU2 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/323098:NWI_RS07225 ^@ http://purl.uniprot.org/uniprot/Q3SST6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RluA family. http://togogenome.org/gene/323098:NWI_RS00540 ^@ http://purl.uniprot.org/uniprot/Q3SWH2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/323098:NWI_RS15835 ^@ http://purl.uniprot.org/uniprot/Q3SN48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS01570 ^@ http://purl.uniprot.org/uniprot/Q3SVX6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/323098:NWI_RS15385 ^@ http://purl.uniprot.org/uniprot/Q3SND3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/323098:NWI_RS12235 ^@ http://purl.uniprot.org/uniprot/Q3SQ38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/323098:NWI_RS05845 ^@ http://purl.uniprot.org/uniprot/Q3STJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/323098:NWI_RS00115 ^@ http://purl.uniprot.org/uniprot/Q3SWQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/323098:NWI_RS11955 ^@ http://purl.uniprot.org/uniprot/Q3SQ93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07375 ^@ http://purl.uniprot.org/uniprot/Q3SSQ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/323098:NWI_RS06865 ^@ http://purl.uniprot.org/uniprot/Q3ST06 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS00550 ^@ http://purl.uniprot.org/uniprot/Q3SWH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/323098:NWI_RS15595 ^@ http://purl.uniprot.org/uniprot/Q3SN94 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/323098:NWI_RS05035 ^@ http://purl.uniprot.org/uniprot/Q3SU08 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/323098:NWI_RS00165 ^@ http://purl.uniprot.org/uniprot/Q3SWP3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer. http://togogenome.org/gene/323098:NWI_RS05095 ^@ http://purl.uniprot.org/uniprot/Q3STZ7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS07965 ^@ http://purl.uniprot.org/uniprot/Q3SSF0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/323098:NWI_RS02640 ^@ http://purl.uniprot.org/uniprot/Q3SVB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS11185 ^@ http://purl.uniprot.org/uniprot/Q3SQP3 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS06345 ^@ http://purl.uniprot.org/uniprot/Q3STA1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS13570 ^@ http://purl.uniprot.org/uniprot/Q3SPC6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/323098:NWI_RS07150 ^@ http://purl.uniprot.org/uniprot/Q3SSV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/323098:NWI_RS00825 ^@ http://purl.uniprot.org/uniprot/Q3SWB7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/323098:NWI_RS00935 ^@ http://purl.uniprot.org/uniprot/Q3SW95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/323098:NWI_RS04040 ^@ http://purl.uniprot.org/uniprot/Q3SUJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS15740 ^@ http://purl.uniprot.org/uniprot/Q3SN67 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/323098:NWI_RS07260 ^@ http://purl.uniprot.org/uniprot/Q3SST0 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/323098:NWI_RS09625 ^@ http://purl.uniprot.org/uniprot/Q3SRI6 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/323098:NWI_RS03895 ^@ http://purl.uniprot.org/uniprot/Q3SUM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS02450 ^@ http://purl.uniprot.org/uniprot/Q3SVF3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/323098:NWI_RS10590 ^@ http://purl.uniprot.org/uniprot/Q3SR01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS02780 ^@ http://purl.uniprot.org/uniprot/Q3SV89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS13030 ^@ http://purl.uniprot.org/uniprot/Q3SPN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS05165 ^@ http://purl.uniprot.org/uniprot/Q3STY0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/323098:NWI_RS08995 ^@ http://purl.uniprot.org/uniprot/Q3SRV5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/323098:NWI_RS13225 ^@ http://purl.uniprot.org/uniprot/Q3SPJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/323098:NWI_RS08705 ^@ http://purl.uniprot.org/uniprot/Q3SS12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS07085 ^@ http://purl.uniprot.org/uniprot/Q3SSW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/323098:NWI_RS03975 ^@ http://purl.uniprot.org/uniprot/Q3SUL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS03945 ^@ http://purl.uniprot.org/uniprot/Q3SUL6 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/323098:NWI_RS08290 ^@ http://purl.uniprot.org/uniprot/Q3SS92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS02325 ^@ http://purl.uniprot.org/uniprot/Q3SVH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/323098:NWI_RS12230 ^@ http://purl.uniprot.org/uniprot/Q3SQ39 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/323098:NWI_RS02010 ^@ http://purl.uniprot.org/uniprot/Q3SVN6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/323098:NWI_RS13060 ^@ http://purl.uniprot.org/uniprot/Q3SPM8 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/323098:NWI_RS01290 ^@ http://purl.uniprot.org/uniprot/Q3SW27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS06310 ^@ http://purl.uniprot.org/uniprot/Q3STA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS02670 ^@ http://purl.uniprot.org/uniprot/Q3SVB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. http://togogenome.org/gene/323098:NWI_RS09405 ^@ http://purl.uniprot.org/uniprot/Q3SRM9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/323098:NWI_RS01170 ^@ http://purl.uniprot.org/uniprot/Q3SUL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/323098:NWI_RS01550 ^@ http://purl.uniprot.org/uniprot/Q3SVY0 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/323098:NWI_RS01235 ^@ http://purl.uniprot.org/uniprot/Q3SW37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity). http://togogenome.org/gene/323098:NWI_RS13250 ^@ http://purl.uniprot.org/uniprot/Q3SPJ1 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/323098:NWI_RS15240 ^@ http://purl.uniprot.org/uniprot/Q3SNF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.|||Carboxysome http://togogenome.org/gene/323098:NWI_RS07430 ^@ http://purl.uniprot.org/uniprot/Q3SSP7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/323098:NWI_RS08835 ^@ http://purl.uniprot.org/uniprot/Q3SRY5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/323098:NWI_RS08725 ^@ http://purl.uniprot.org/uniprot/Q3SS07 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS13545 ^@ http://purl.uniprot.org/uniprot/Q3SPD1 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family. DsbA subfamily.|||May be required for disulfide bond formation in some proteins. http://togogenome.org/gene/323098:NWI_RS04985 ^@ http://purl.uniprot.org/uniprot/Q3SU17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Membrane http://togogenome.org/gene/323098:NWI_RS03305 ^@ http://purl.uniprot.org/uniprot/Q3SUY7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS08855 ^@ http://purl.uniprot.org/uniprot/Q3SRY1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/323098:NWI_RS09230 ^@ http://purl.uniprot.org/uniprot/Q3SRR1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/323098:NWI_RS10320 ^@ http://purl.uniprot.org/uniprot/Q3SR53 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/323098:NWI_RS14605 ^@ http://purl.uniprot.org/uniprot/Q3SNS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/323098:NWI_RS06790 ^@ http://purl.uniprot.org/uniprot/Q3ST21 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/323098:NWI_RS16025 ^@ http://purl.uniprot.org/uniprot/Q3SN14 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS00095 ^@ http://purl.uniprot.org/uniprot/Q3SWQ6 ^@ Similarity ^@ Belongs to the UPF0053 family. Hemolysin C subfamily. http://togogenome.org/gene/323098:NWI_RS01560 ^@ http://purl.uniprot.org/uniprot/Q3SVX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS09505 ^@ http://purl.uniprot.org/uniprot/Q3SRK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS01940 ^@ http://purl.uniprot.org/uniprot/Q3SVQ1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/323098:NWI_RS08780 ^@ http://purl.uniprot.org/uniprot/Q3SRZ6 ^@ Similarity ^@ Belongs to the YicC/YloC family. http://togogenome.org/gene/323098:NWI_RS09265 ^@ http://purl.uniprot.org/uniprot/Q3SRQ4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS06805 ^@ http://purl.uniprot.org/uniprot/Q3ST18 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/323098:NWI_RS01970 ^@ http://purl.uniprot.org/uniprot/Q3SVP5 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/323098:NWI_RS07100 ^@ http://purl.uniprot.org/uniprot/Q3SSW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/323098:NWI_RS09775 ^@ http://purl.uniprot.org/uniprot/Q3SRF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/323098:NWI_RS11045 ^@ http://purl.uniprot.org/uniprot/Q3SQR9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/323098:NWI_RS00855 ^@ http://purl.uniprot.org/uniprot/Q3SWB1 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/323098:NWI_RS05555 ^@ http://purl.uniprot.org/uniprot/Q3STQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/323098:NWI_RS00245 ^@ http://purl.uniprot.org/uniprot/Q3SWM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS11870 ^@ http://purl.uniprot.org/uniprot/Q3SQB0 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/323098:NWI_RS04450 ^@ http://purl.uniprot.org/uniprot/Q3SUC0 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/323098:NWI_RS15530 ^@ http://purl.uniprot.org/uniprot/Q3SNA6 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/323098:NWI_RS06640 ^@ http://purl.uniprot.org/uniprot/Q3ST46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/323098:NWI_RS05225 ^@ http://purl.uniprot.org/uniprot/Q3STW8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/323098:NWI_RS07595 ^@ http://purl.uniprot.org/uniprot/Q3SSL5 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/323098:NWI_RS06785 ^@ http://purl.uniprot.org/uniprot/Q3ST22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/323098:NWI_RS09485 ^@ http://purl.uniprot.org/uniprot/Q3SRL3 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/323098:NWI_RS15985 ^@ http://purl.uniprot.org/uniprot/Q3SN22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS11230 ^@ http://purl.uniprot.org/uniprot/Q3SQN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/323098:NWI_RS05175 ^@ http://purl.uniprot.org/uniprot/Q3STX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/323098:NWI_RS15910 ^@ http://purl.uniprot.org/uniprot/Q3SN36 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS11740 ^@ http://purl.uniprot.org/uniprot/Q3SQD5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/323098:NWI_RS01195 ^@ http://purl.uniprot.org/uniprot/Q3SUL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS14130 ^@ http://purl.uniprot.org/uniprot/Q3SP19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/323098:NWI_RS07365 ^@ http://purl.uniprot.org/uniprot/Q3SSR0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/323098:NWI_RS10510 ^@ http://purl.uniprot.org/uniprot/Q3SR16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS12845 ^@ http://purl.uniprot.org/uniprot/Q3SPS1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS14335 ^@ http://purl.uniprot.org/uniprot/Q3SNX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/323098:NWI_RS11215 ^@ http://purl.uniprot.org/uniprot/Q3SQN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS00635 ^@ http://purl.uniprot.org/uniprot/Q3SWF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS12075 ^@ http://purl.uniprot.org/uniprot/Q3SQ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS02335 ^@ http://purl.uniprot.org/uniprot/Q3SVH5 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/323098:NWI_RS12725 ^@ http://purl.uniprot.org/uniprot/Q3SPU2 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/323098:NWI_RS09940 ^@ http://purl.uniprot.org/uniprot/Q3SRC7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/323098:NWI_RS13730 ^@ http://purl.uniprot.org/uniprot/Q3SP95 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS05180 ^@ http://purl.uniprot.org/uniprot/Q3STX7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/323098:NWI_RS09480 ^@ http://purl.uniprot.org/uniprot/Q3SRL4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/323098:NWI_RS06845 ^@ http://purl.uniprot.org/uniprot/Q3ST10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS07530 ^@ http://purl.uniprot.org/uniprot/Q3SSM7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/323098:NWI_RS01925 ^@ http://purl.uniprot.org/uniprot/Q3SVQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/323098:NWI_RS00805 ^@ http://purl.uniprot.org/uniprot/Q3SWC1 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS01675 ^@ http://purl.uniprot.org/uniprot/Q3SVV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/323098:NWI_RS00175 ^@ http://purl.uniprot.org/uniprot/Q3SWP1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/323098:NWI_RS15700 ^@ http://purl.uniprot.org/uniprot/Q3SN75 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/323098:NWI_RS00740 ^@ http://purl.uniprot.org/uniprot/Q3SWD2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.|||Cell inner membrane|||Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function. http://togogenome.org/gene/323098:NWI_RS10430 ^@ http://purl.uniprot.org/uniprot/Q3SR31 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/323098:NWI_RS06100 ^@ http://purl.uniprot.org/uniprot/Q3STE9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/323098:NWI_RS01265 ^@ http://purl.uniprot.org/uniprot/Q3SW31 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS15025 ^@ http://purl.uniprot.org/uniprot/Q3SNK0 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS01640 ^@ http://purl.uniprot.org/uniprot/Q3SVW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/323098:NWI_RS05120 ^@ http://purl.uniprot.org/uniprot/Q3STZ0 ^@ Similarity ^@ Belongs to the UPF0335 family. http://togogenome.org/gene/323098:NWI_RS12370 ^@ http://purl.uniprot.org/uniprot/Q3SQ09 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS08320 ^@ http://purl.uniprot.org/uniprot/Q3SS86 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/323098:NWI_RS00405 ^@ http://purl.uniprot.org/uniprot/Q3SWJ7 ^@ Function|||Subunit ^@ Homotrimer.|||In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. http://togogenome.org/gene/323098:NWI_RS01965 ^@ http://purl.uniprot.org/uniprot/Q3SVP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS12180 ^@ http://purl.uniprot.org/uniprot/Q3SQ49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS14220 ^@ http://purl.uniprot.org/uniprot/Q3SP01 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/323098:NWI_RS15425 ^@ http://purl.uniprot.org/uniprot/Q3SNC6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/323098:NWI_RS12620 ^@ http://purl.uniprot.org/uniprot/Q3SPW1 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/323098:NWI_RS05155 ^@ http://purl.uniprot.org/uniprot/Q3STY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/323098:NWI_RS02025 ^@ http://purl.uniprot.org/uniprot/Q3SVN3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/323098:NWI_RS07875 ^@ http://purl.uniprot.org/uniprot/Q3SSG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/323098:NWI_RS02525 ^@ http://purl.uniprot.org/uniprot/Q3SVE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/323098:NWI_RS12355 ^@ http://purl.uniprot.org/uniprot/Q3SQ12 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/323098:NWI_RS04900 ^@ http://purl.uniprot.org/uniprot/Q3SU34 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/323098:NWI_RS11660 ^@ http://purl.uniprot.org/uniprot/Q3SQF2 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/323098:NWI_RS05050 ^@ http://purl.uniprot.org/uniprot/Q3SU05 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/323098:NWI_RS14345 ^@ http://purl.uniprot.org/uniprot/Q3SNX6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/323098:NWI_RS02055 ^@ http://purl.uniprot.org/uniprot/Q3SVM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family. Hemolysin C subfamily.|||Membrane http://togogenome.org/gene/323098:NWI_RS15345 ^@ http://purl.uniprot.org/uniprot/Q3SNE1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/323098:NWI_RS09450 ^@ http://purl.uniprot.org/uniprot/Q3SRM0 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/323098:NWI_RS00160 ^@ http://purl.uniprot.org/uniprot/Q3SWP4 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS06890 ^@ http://purl.uniprot.org/uniprot/Q3ST01 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/323098:NWI_RS00930 ^@ http://purl.uniprot.org/uniprot/Q3SW96 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/323098:NWI_RS11880 ^@ http://purl.uniprot.org/uniprot/Q3SQA8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/323098:NWI_RS13215 ^@ http://purl.uniprot.org/uniprot/Q3SPJ7 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/323098:NWI_RS05455 ^@ http://purl.uniprot.org/uniprot/Q3STS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/323098:NWI_RS12505 ^@ http://purl.uniprot.org/uniprot/Q3SPY2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/323098:NWI_RS02220 ^@ http://purl.uniprot.org/uniprot/Q3SVJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/323098:NWI_RS07355 ^@ http://purl.uniprot.org/uniprot/Q3SSR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COX15/CtaA family. Type 2 subfamily.|||Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.|||Cell membrane|||Interacts with CtaB. http://togogenome.org/gene/323098:NWI_RS15445 ^@ http://purl.uniprot.org/uniprot/Q3SNC2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/323098:NWI_RS03950 ^@ http://purl.uniprot.org/uniprot/Q3SUL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/323098:NWI_RS13140 ^@ http://purl.uniprot.org/uniprot/Q3SPL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/323098:NWI_RS07480 ^@ http://purl.uniprot.org/uniprot/Q3SSN7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/323098:NWI_RS08600 ^@ http://purl.uniprot.org/uniprot/Q3SS33 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS07105 ^@ http://purl.uniprot.org/uniprot/Q3SSW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/323098:NWI_RS07075 ^@ http://purl.uniprot.org/uniprot/Q3SSW6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/323098:NWI_RS00280 ^@ http://purl.uniprot.org/uniprot/Q3SWM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS07570 ^@ http://purl.uniprot.org/uniprot/Q3SSL9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/323098:NWI_RS09790 ^@ http://purl.uniprot.org/uniprot/Q3SRF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS13345 ^@ http://purl.uniprot.org/uniprot/Q3SPH2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/323098:NWI_RS07840 ^@ http://purl.uniprot.org/uniprot/Q3SSH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.|||Membrane http://togogenome.org/gene/323098:NWI_RS13610 ^@ http://purl.uniprot.org/uniprot/Q3SPB8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. http://togogenome.org/gene/323098:NWI_RS05610 ^@ http://purl.uniprot.org/uniprot/Q3STP0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS09280 ^@ http://purl.uniprot.org/uniprot/Q3SRQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/323098:NWI_RS07950 ^@ http://purl.uniprot.org/uniprot/Q3SSF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS09665 ^@ http://purl.uniprot.org/uniprot/Q3SRH8 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/323098:NWI_RS00155 ^@ http://purl.uniprot.org/uniprot/Q3SWP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/323098:NWI_RS12755 ^@ http://purl.uniprot.org/uniprot/Q3SPT9 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS03450 ^@ http://purl.uniprot.org/uniprot/Q3SUW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS12085 ^@ http://purl.uniprot.org/uniprot/Q3SQ67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS10105 ^@ http://purl.uniprot.org/uniprot/Q3SR96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/323098:NWI_RS09865 ^@ http://purl.uniprot.org/uniprot/Q3SRD9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/323098:NWI_RS10375 ^@ http://purl.uniprot.org/uniprot/Q3SR42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.|||Cell inner membrane|||Forms a complex with DabB.|||Part of an energy-coupled inorganic carbon pump. http://togogenome.org/gene/323098:NWI_RS01750 ^@ http://purl.uniprot.org/uniprot/Q3SVT9 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/323098:NWI_RS01085 ^@ http://purl.uniprot.org/uniprot/Q3SW65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS12200 ^@ http://purl.uniprot.org/uniprot/Q3SQ45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/323098:NWI_RS01190 ^@ http://purl.uniprot.org/uniprot/Q3SUL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/323098:NWI_RS16260 ^@ http://purl.uniprot.org/uniprot/Q3SMW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS00535 ^@ http://purl.uniprot.org/uniprot/Q3SWH3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rho family.|||Cell inner membrane|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS13790 ^@ http://purl.uniprot.org/uniprot/Q3SP83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS15010 ^@ http://purl.uniprot.org/uniprot/Q3SNK3 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/323098:NWI_RS01775 ^@ http://purl.uniprot.org/uniprot/Q3SVT4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/323098:NWI_RS00400 ^@ http://purl.uniprot.org/uniprot/Q3SWJ8 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/323098:NWI_RS08200 ^@ http://purl.uniprot.org/uniprot/Q3SSB2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/323098:NWI_RS09575 ^@ http://purl.uniprot.org/uniprot/Q3SRJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PpiC/parvulin rotamase family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS10170 ^@ http://purl.uniprot.org/uniprot/Q3SR83 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the PduL family.|||Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/323098:NWI_RS03130 ^@ http://purl.uniprot.org/uniprot/Q3SV23 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/323098:NWI_RS06295 ^@ http://purl.uniprot.org/uniprot/Q3STB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/323098:NWI_RS12585 ^@ http://purl.uniprot.org/uniprot/Q3SPW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS11410 ^@ http://purl.uniprot.org/uniprot/Q3SQJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell inner membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/323098:NWI_RS13270 ^@ http://purl.uniprot.org/uniprot/Q3SPI7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/323098:NWI_RS06205 ^@ http://purl.uniprot.org/uniprot/Q3STC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS16090 ^@ http://purl.uniprot.org/uniprot/Q3SN02 ^@ Similarity ^@ Belongs to the RelE toxin family. http://togogenome.org/gene/323098:NWI_RS13380 ^@ http://purl.uniprot.org/uniprot/Q3SPG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/323098:NWI_RS15755 ^@ http://purl.uniprot.org/uniprot/Q3SN64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS14020 ^@ http://purl.uniprot.org/uniprot/Q3SP40 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/323098:NWI_RS11350 ^@ http://purl.uniprot.org/uniprot/Q3SQL1 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/323098:NWI_RS07825 ^@ http://purl.uniprot.org/uniprot/Q3SSH7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/323098:NWI_RS08355 ^@ http://purl.uniprot.org/uniprot/Q3SS79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/323098:NWI_RS03685 ^@ http://purl.uniprot.org/uniprot/Q3SUR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/323098:NWI_RS03925 ^@ http://purl.uniprot.org/uniprot/Q3SUM0 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/323098:NWI_RS05450 ^@ http://purl.uniprot.org/uniprot/Q3STS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/323098:NWI_RS05465 ^@ http://purl.uniprot.org/uniprot/Q3STR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/323098:NWI_RS14535 ^@ http://purl.uniprot.org/uniprot/Q3SNT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS01545 ^@ http://purl.uniprot.org/uniprot/Q3SVY1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/323098:NWI_RS15485 ^@ http://purl.uniprot.org/uniprot/Q3SNB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/323098:NWI_RS06325 ^@ http://purl.uniprot.org/uniprot/Q3STA5 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/323098:NWI_RS15605 ^@ http://purl.uniprot.org/uniprot/Q3SN92 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/323098:NWI_RS01230 ^@ http://purl.uniprot.org/uniprot/Q3SW38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. http://togogenome.org/gene/323098:NWI_RS03695 ^@ http://purl.uniprot.org/uniprot/Q3SUR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS15815 ^@ http://purl.uniprot.org/uniprot/Q3SN52 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/323098:NWI_RS01955 ^@ http://purl.uniprot.org/uniprot/Q3SVP8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/323098:NWI_RS06485 ^@ http://purl.uniprot.org/uniprot/Q3ST76 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/323098:NWI_RS07325 ^@ http://purl.uniprot.org/uniprot/Q3SSR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/323098:NWI_RS00845 ^@ http://purl.uniprot.org/uniprot/Q3SWB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS04400 ^@ http://purl.uniprot.org/uniprot/Q3SUD0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/323098:NWI_RS01725 ^@ http://purl.uniprot.org/uniprot/Q3SVU4 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/323098:NWI_RS09000 ^@ http://purl.uniprot.org/uniprot/Q3SRV4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/323098:NWI_RS11725 ^@ http://purl.uniprot.org/uniprot/Q3SQD9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS07340 ^@ http://purl.uniprot.org/uniprot/Q3SSR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS05720 ^@ http://purl.uniprot.org/uniprot/Q3STL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||Periplasm|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/323098:NWI_RS00355 ^@ http://purl.uniprot.org/uniprot/Q3SWK6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/323098:NWI_RS06645 ^@ http://purl.uniprot.org/uniprot/Q3ST45 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/323098:NWI_RS07110 ^@ http://purl.uniprot.org/uniprot/Q3SSV9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS13940 ^@ http://purl.uniprot.org/uniprot/Q3SP55 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/323098:NWI_RS06775 ^@ http://purl.uniprot.org/uniprot/Q3ST25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/323098:NWI_RS00425 ^@ http://purl.uniprot.org/uniprot/Q3SWJ4 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/323098:NWI_RS10515 ^@ http://purl.uniprot.org/uniprot/Q3SR15 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS03265 ^@ http://purl.uniprot.org/uniprot/Q3SUZ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/323098:NWI_RS10600 ^@ http://purl.uniprot.org/uniprot/Q3SQZ9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/323098:NWI_RS07450 ^@ http://purl.uniprot.org/uniprot/Q3SSP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS01880 ^@ http://purl.uniprot.org/uniprot/Q3SVR3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/323098:NWI_RS16000 ^@ http://purl.uniprot.org/uniprot/Q3SN19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/323098:NWI_RS13065 ^@ http://purl.uniprot.org/uniprot/Q3SPM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/323098:NWI_RS02200 ^@ http://purl.uniprot.org/uniprot/Q3SVJ9 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/323098:NWI_RS00555 ^@ http://purl.uniprot.org/uniprot/Q3SWG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS04590 ^@ http://purl.uniprot.org/uniprot/Q3SU94 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/323098:NWI_RS03075 ^@ http://purl.uniprot.org/uniprot/Q3SV34 ^@ Cofactor|||Function|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. http://togogenome.org/gene/323098:NWI_RS09695 ^@ http://purl.uniprot.org/uniprot/Q3SRH2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/323098:NWI_RS05140 ^@ http://purl.uniprot.org/uniprot/Q3STY6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/323098:NWI_RS13150 ^@ http://purl.uniprot.org/uniprot/Q3SPL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/323098:NWI_RS11265 ^@ http://purl.uniprot.org/uniprot/Q3SQM7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/323098:NWI_RS10365 ^@ http://purl.uniprot.org/uniprot/Q3SR44 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS07005 ^@ http://purl.uniprot.org/uniprot/Q3SSY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/323098:NWI_RS05940 ^@ http://purl.uniprot.org/uniprot/Q3STH9 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/323098:NWI_RS03280 ^@ http://purl.uniprot.org/uniprot/Q3SUZ2 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/323098:NWI_RS01200 ^@ http://purl.uniprot.org/uniprot/Q3SW44 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/323098:NWI_RS11180 ^@ http://purl.uniprot.org/uniprot/Q3SQP4 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS12675 ^@ http://purl.uniprot.org/uniprot/Q3SPV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS13525 ^@ http://purl.uniprot.org/uniprot/Q3SPD5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/323098:NWI_RS02745 ^@ http://purl.uniprot.org/uniprot/Q3SV95 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/323098:NWI_RS15930 ^@ http://purl.uniprot.org/uniprot/Q3SN33 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/323098:NWI_RS11650 ^@ http://purl.uniprot.org/uniprot/Q3SQF4 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/323098:NWI_RS15870 ^@ http://purl.uniprot.org/uniprot/Q3SN43 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS05170 ^@ http://purl.uniprot.org/uniprot/Q3STX9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell inner membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Membrane http://togogenome.org/gene/323098:NWI_RS01540 ^@ http://purl.uniprot.org/uniprot/Q3SVY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS02185 ^@ http://purl.uniprot.org/uniprot/Q3SVK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/323098:NWI_RS03295 ^@ http://purl.uniprot.org/uniprot/Q3SUY9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/323098:NWI_RS04640 ^@ http://purl.uniprot.org/uniprot/Q3SU84 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/323098:NWI_RS02690 ^@ http://purl.uniprot.org/uniprot/Q3SVA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/323098:NWI_RS05690 ^@ http://purl.uniprot.org/uniprot/Q3STM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/323098:NWI_RS11550 ^@ http://purl.uniprot.org/uniprot/Q3SQH2 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/323098:NWI_RS08240 ^@ http://purl.uniprot.org/uniprot/Q3SSA3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/323098:NWI_RS05290 ^@ http://purl.uniprot.org/uniprot/Q3STV5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/323098:NWI_RS09725 ^@ http://purl.uniprot.org/uniprot/Q3SRG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS09285 ^@ http://purl.uniprot.org/uniprot/Q3SRQ0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/323098:NWI_RS13620 ^@ http://purl.uniprot.org/uniprot/Q3SPB6 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/323098:NWI_RS15535 ^@ http://purl.uniprot.org/uniprot/Q3SNA5 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/323098:NWI_RS08810 ^@ http://purl.uniprot.org/uniprot/Q3SRZ0 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/323098:NWI_RS06705 ^@ http://purl.uniprot.org/uniprot/Q3ST36 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/323098:NWI_RS05950 ^@ http://purl.uniprot.org/uniprot/Q3STH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS00915 ^@ http://purl.uniprot.org/uniprot/Q3SW99 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS13290 ^@ http://purl.uniprot.org/uniprot/Q3SPI3 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/323098:NWI_RS02575 ^@ http://purl.uniprot.org/uniprot/Q3SVC9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/323098:NWI_RS06825 ^@ http://purl.uniprot.org/uniprot/Q3ST14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/323098:NWI_RS13280 ^@ http://purl.uniprot.org/uniprot/Q3SPI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/323098:NWI_RS14360 ^@ http://purl.uniprot.org/uniprot/Q3SNX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Monomer. http://togogenome.org/gene/323098:NWI_RS03275 ^@ http://purl.uniprot.org/uniprot/Q3SUZ3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/323098:NWI_RS10065 ^@ http://purl.uniprot.org/uniprot/Q3SRA2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/323098:NWI_RS08670 ^@ http://purl.uniprot.org/uniprot/Q3SS19 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/323098:NWI_RS12175 ^@ http://purl.uniprot.org/uniprot/Q3SQ50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/323098:NWI_RS03580 ^@ http://purl.uniprot.org/uniprot/Q3SUT3 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/323098:NWI_RS13865 ^@ http://purl.uniprot.org/uniprot/Q3SP69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/323098:NWI_RS03970 ^@ http://purl.uniprot.org/uniprot/Q3SUL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/323098:NWI_RS15440 ^@ http://purl.uniprot.org/uniprot/Q3SNC3 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/323098:NWI_RS15095 ^@ http://purl.uniprot.org/uniprot/Q3SNI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS02225 ^@ http://purl.uniprot.org/uniprot/Q3SVJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/323098:NWI_RS02105 ^@ http://purl.uniprot.org/uniprot/Q3SVL8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/323098:NWI_RS00275 ^@ http://purl.uniprot.org/uniprot/Q3SWM1 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/323098:NWI_RS12215 ^@ http://purl.uniprot.org/uniprot/Q3SQ42 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/323098:NWI_RS04595 ^@ http://purl.uniprot.org/uniprot/Q3SU93 ^@ Similarity ^@ Belongs to the TULIP P47 family. http://togogenome.org/gene/323098:NWI_RS14165 ^@ http://purl.uniprot.org/uniprot/Q3SP12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/323098:NWI_RS09755 ^@ http://purl.uniprot.org/uniprot/Q3SRG0 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/323098:NWI_RS16005 ^@ http://purl.uniprot.org/uniprot/Q3SN18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/323098:NWI_RS11830 ^@ http://purl.uniprot.org/uniprot/Q3SQB8 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/323098:NWI_RS07175 ^@ http://purl.uniprot.org/uniprot/Q3SSU6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/323098:NWI_RS11205 ^@ http://purl.uniprot.org/uniprot/Q3SQN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS14980 ^@ http://purl.uniprot.org/uniprot/Q3SNK8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS02285 ^@ http://purl.uniprot.org/uniprot/Q3SVI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/323098:NWI_RS00990 ^@ http://purl.uniprot.org/uniprot/Q3SW84 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane http://togogenome.org/gene/323098:NWI_RS07250 ^@ http://purl.uniprot.org/uniprot/Q3SST2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/323098:NWI_RS15845 ^@ http://purl.uniprot.org/uniprot/Q3SN46 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/323098:NWI_RS06990 ^@ http://purl.uniprot.org/uniprot/Q3SSY4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/323098:NWI_RS12245 ^@ http://purl.uniprot.org/uniprot/Q3SQ36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS01975 ^@ http://purl.uniprot.org/uniprot/Q3SVP3 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/323098:NWI_RS09365 ^@ http://purl.uniprot.org/uniprot/Q3SRN6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/323098:NWI_RS07475 ^@ http://purl.uniprot.org/uniprot/Q3SSN8 ^@ Function|||Similarity ^@ Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. http://togogenome.org/gene/323098:NWI_RS13070 ^@ http://purl.uniprot.org/uniprot/Q3SPM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/323098:NWI_RS03270 ^@ http://purl.uniprot.org/uniprot/Q3SUZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/323098:NWI_RS07080 ^@ http://purl.uniprot.org/uniprot/Q3SSW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS00345 ^@ http://purl.uniprot.org/uniprot/Q3SWK8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/323098:NWI_RS04035 ^@ http://purl.uniprot.org/uniprot/Q3SUJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS07895 ^@ http://purl.uniprot.org/uniprot/Q3SSG3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS10025 ^@ http://purl.uniprot.org/uniprot/Q3SRB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/323098:NWI_RS12420 ^@ http://purl.uniprot.org/uniprot/Q3SPZ9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/323098:NWI_RS10410 ^@ http://purl.uniprot.org/uniprot/Q3SR34 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS07015 ^@ http://purl.uniprot.org/uniprot/Q3SSX9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/323098:NWI_RS05550 ^@ http://purl.uniprot.org/uniprot/Q3STQ2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/323098:NWI_RS01240 ^@ http://purl.uniprot.org/uniprot/Q3SW36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/323098:NWI_RS10460 ^@ http://purl.uniprot.org/uniprot/Q3SR25 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/323098:NWI_RS11930 ^@ http://purl.uniprot.org/uniprot/Q3SQ98 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/323098:NWI_RS01270 ^@ http://purl.uniprot.org/uniprot/Q3SW30 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/323098:NWI_RS13220 ^@ http://purl.uniprot.org/uniprot/Q3SPJ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/323098:NWI_RS14355 ^@ http://purl.uniprot.org/uniprot/Q3SNX4 ^@ Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.|||Sulfate-activating enzymes, NodP and NodQ, may be physically associated. http://togogenome.org/gene/323098:NWI_RS08755 ^@ http://purl.uniprot.org/uniprot/Q3SS01 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS11245 ^@ http://purl.uniprot.org/uniprot/Q3SQN1 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/323098:NWI_RS01015 ^@ http://purl.uniprot.org/uniprot/Q3SW79 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/323098:NWI_RS05520 ^@ http://purl.uniprot.org/uniprot/Q3STQ8 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/323098:NWI_RS12405 ^@ http://purl.uniprot.org/uniprot/Q3SQ02 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS09560 ^@ http://purl.uniprot.org/uniprot/Q3SRJ8 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS02305 ^@ http://purl.uniprot.org/uniprot/Q3SVI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS14625 ^@ http://purl.uniprot.org/uniprot/Q3SNS2 ^@ Cofactor|||Similarity ^@ Belongs to the ApbE family.|||Magnesium. Can also use manganese. http://togogenome.org/gene/323098:NWI_RS13725 ^@ http://purl.uniprot.org/uniprot/Q3SP96 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/323098:NWI_RS09645 ^@ http://purl.uniprot.org/uniprot/Q3SRI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/323098:NWI_RS11225 ^@ http://purl.uniprot.org/uniprot/Q3SQN5 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/323098:NWI_RS09770 ^@ http://purl.uniprot.org/uniprot/Q3SRF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/323098:NWI_RS01735 ^@ http://purl.uniprot.org/uniprot/Q3SVU2 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. http://togogenome.org/gene/323098:NWI_RS01010 ^@ http://purl.uniprot.org/uniprot/Q3SW80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/323098:NWI_RS00570 ^@ http://purl.uniprot.org/uniprot/Q3SWG6 ^@ Similarity ^@ Belongs to the Tim44 family. http://togogenome.org/gene/323098:NWI_RS09620 ^@ http://purl.uniprot.org/uniprot/Q3SRI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/323098:NWI_RS13535 ^@ http://purl.uniprot.org/uniprot/Q3SPD3 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/323098:NWI_RS03535 ^@ http://purl.uniprot.org/uniprot/Q3SUU3 ^@ Function|||Similarity ^@ Belongs to the SsuD family.|||Catalyzes the desulfonation of aliphatic sulfonates. http://togogenome.org/gene/323098:NWI_RS06985 ^@ http://purl.uniprot.org/uniprot/Q3SSY5 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/323098:NWI_RS07360 ^@ http://purl.uniprot.org/uniprot/Q3SSR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/323098:NWI_RS01825 ^@ http://purl.uniprot.org/uniprot/Q3SVS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/323098:NWI_RS03960 ^@ http://purl.uniprot.org/uniprot/Q3SUL3|||http://purl.uniprot.org/uniprot/Q3SW48 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. http://togogenome.org/gene/323098:NWI_RS05760 ^@ http://purl.uniprot.org/uniprot/Q3STL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/323098:NWI_RS05535 ^@ http://purl.uniprot.org/uniprot/Q3STQ5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/323098:NWI_RS02495 ^@ http://purl.uniprot.org/uniprot/Q3SVE6 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/323098:NWI_RS01075 ^@ http://purl.uniprot.org/uniprot/Q3SW67 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/323098:NWI_RS07300 ^@ http://purl.uniprot.org/uniprot/Q3SSS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/323098:NWI_RS07290 ^@ http://purl.uniprot.org/uniprot/Q3SSS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/323098:NWI_RS09715 ^@ http://purl.uniprot.org/uniprot/Q3SRG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/323098:NWI_RS10845 ^@ http://purl.uniprot.org/uniprot/Q3SQV7 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS07170 ^@ http://purl.uniprot.org/uniprot/Q3SSU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/323098:NWI_RS05505 ^@ http://purl.uniprot.org/uniprot/Q3STR1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/323098:NWI_RS01565 ^@ http://purl.uniprot.org/uniprot/Q3SVX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/323098:NWI_RS12430 ^@ http://purl.uniprot.org/uniprot/Q3SPZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HisA/HisF family.|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/323098:NWI_RS09225 ^@ http://purl.uniprot.org/uniprot/Q3SRR2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/323098:NWI_RS02030 ^@ http://purl.uniprot.org/uniprot/Q3SVN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS13530 ^@ http://purl.uniprot.org/uniprot/Q3SPD4 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/323098:NWI_RS07295 ^@ http://purl.uniprot.org/uniprot/Q3SSS3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/323098:NWI_RS12045 ^@ http://purl.uniprot.org/uniprot/Q3SQ75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HemJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS09640 ^@ http://purl.uniprot.org/uniprot/Q3SRI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/323098:NWI_RS05395 ^@ http://purl.uniprot.org/uniprot/Q3STT3 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/323098:NWI_RS04610 ^@ http://purl.uniprot.org/uniprot/Q3SU90 ^@ Similarity ^@ Belongs to the TULIP P47 family. http://togogenome.org/gene/323098:NWI_RS00135 ^@ http://purl.uniprot.org/uniprot/Q3SWP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/323098:NWI_RS09270 ^@ http://purl.uniprot.org/uniprot/Q3SRQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/323098:NWI_RS02205 ^@ http://purl.uniprot.org/uniprot/Q3SVJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/323098:NWI_RS10035 ^@ http://purl.uniprot.org/uniprot/Q3SRA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/323098:NWI_RS02540 ^@ http://purl.uniprot.org/uniprot/Q3SVD6 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers. http://togogenome.org/gene/323098:NWI_RS00490 ^@ http://purl.uniprot.org/uniprot/Q3SWI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/323098:NWI_RS01740 ^@ http://purl.uniprot.org/uniprot/Q3SVU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/323098:NWI_RS10060 ^@ http://purl.uniprot.org/uniprot/Q3SRA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer. http://togogenome.org/gene/323098:NWI_RS01135 ^@ http://purl.uniprot.org/uniprot/Q3SW57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/323098:NWI_RS08785 ^@ http://purl.uniprot.org/uniprot/Q3SRZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/323098:NWI_RS08625 ^@ http://purl.uniprot.org/uniprot/Q3SS28 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/323098:NWI_RS06575 ^@ http://purl.uniprot.org/uniprot/Q3ST59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS14155 ^@ http://purl.uniprot.org/uniprot/Q3SP14 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/323098:NWI_RS06760 ^@ http://purl.uniprot.org/uniprot/Q3ST28 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/323098:NWI_RS05855 ^@ http://purl.uniprot.org/uniprot/Q3STJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/323098:NWI_RS07955 ^@ http://purl.uniprot.org/uniprot/Q3SSF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/323098:NWI_RS05445 ^@ http://purl.uniprot.org/uniprot/Q3STS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/323098:NWI_RS03445 ^@ http://purl.uniprot.org/uniprot/Q3SUW1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alphaproteobacteria porin family.|||Cell outer membrane|||Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.|||Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane. http://togogenome.org/gene/323098:NWI_RS02210 ^@ http://purl.uniprot.org/uniprot/Q3SVJ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/323098:NWI_RS06245 ^@ http://purl.uniprot.org/uniprot/Q3STC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/323098:NWI_RS14555 ^@ http://purl.uniprot.org/uniprot/Q3SNT5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/323098:NWI_RS04935 ^@ http://purl.uniprot.org/uniprot/Q3SU26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer.