http://togogenome.org/gene/326424:FRAAL_RS27345 ^@ http://purl.uniprot.org/uniprot/Q0RCD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/326424:FRAAL_RS09515 ^@ http://purl.uniprot.org/uniprot/Q0RNQ8 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-Y family.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/326424:FRAAL_RS07860 ^@ http://purl.uniprot.org/uniprot/Q0RPQ6 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/326424:FRAAL_RS10095 ^@ http://purl.uniprot.org/uniprot/Q0RND1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/326424:FRAAL_RS13100 ^@ http://purl.uniprot.org/uniprot/Q0RLG0 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/326424:FRAAL_RS21255 ^@ http://purl.uniprot.org/uniprot/Q0RG76 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS12160 ^@ http://purl.uniprot.org/uniprot/Q0RM16 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS08525 ^@ http://purl.uniprot.org/uniprot/Q0RPB6 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/326424:FRAAL_RS25025 ^@ http://purl.uniprot.org/uniprot/Q0RDT8 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS04230 ^@ http://purl.uniprot.org/uniprot/Q0RS15 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS21015 ^@ http://purl.uniprot.org/uniprot/Q0RGD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS07780 ^@ http://purl.uniprot.org/uniprot/Q0RPS4 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS27920 ^@ http://purl.uniprot.org/uniprot/Q0RC09 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/326424:FRAAL_RS15065 ^@ http://purl.uniprot.org/uniprot/Q0RK63 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS28690 ^@ http://purl.uniprot.org/uniprot/Q0RBI8 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/326424:FRAAL_RS17655 ^@ http://purl.uniprot.org/uniprot/Q0RIJ5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/326424:FRAAL_RS00525 ^@ http://purl.uniprot.org/uniprot/Q0RUF0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS07680 ^@ http://purl.uniprot.org/uniprot/Q0RPU4 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/326424:FRAAL_RS25620 ^@ http://purl.uniprot.org/uniprot/Q0RDG0 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/326424:FRAAL_RS21815 ^@ http://purl.uniprot.org/uniprot/Q0RFU6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/326424:FRAAL_RS25005 ^@ http://purl.uniprot.org/uniprot/Q0RDU3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/326424:FRAAL_RS24030 ^@ http://purl.uniprot.org/uniprot/Q0REG1 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/326424:FRAAL_RS10380 ^@ http://purl.uniprot.org/uniprot/Q0RN73 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/326424:FRAAL_RS10650 ^@ http://purl.uniprot.org/uniprot/Q0RN04 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/326424:FRAAL_RS22520 ^@ http://purl.uniprot.org/uniprot/Q0RFE1 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/326424:FRAAL_RS08445 ^@ http://purl.uniprot.org/uniprot/Q0RPD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/326424:FRAAL_RS03400 ^@ http://purl.uniprot.org/uniprot/Q0RSK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS06570 ^@ http://purl.uniprot.org/uniprot/Q0RQK9 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/326424:FRAAL_RS08020 ^@ http://purl.uniprot.org/uniprot/Q0RPM3 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/326424:FRAAL_RS25730 ^@ http://purl.uniprot.org/uniprot/Q0RDD4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS04455 ^@ http://purl.uniprot.org/uniprot/Q0RRW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS26130 ^@ http://purl.uniprot.org/uniprot/Q0RD51 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/326424:FRAAL_RS27365 ^@ http://purl.uniprot.org/uniprot/Q0RCD2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/326424:FRAAL_RS23425 ^@ http://purl.uniprot.org/uniprot/Q0REU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/326424:FRAAL_RS25590 ^@ http://purl.uniprot.org/uniprot/Q0RDG7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/326424:FRAAL_RS03985 ^@ http://purl.uniprot.org/uniprot/Q0RS68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS04645 ^@ http://purl.uniprot.org/uniprot/Q0RRT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/326424:FRAAL_RS06130 ^@ http://purl.uniprot.org/uniprot/Q0RQV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS28655 ^@ http://purl.uniprot.org/uniprot/Q0RBJ5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/326424:FRAAL_RS24895 ^@ http://purl.uniprot.org/uniprot/Q0RDW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS28570 ^@ http://purl.uniprot.org/uniprot/Q0RBL3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/326424:FRAAL_RS22620 ^@ http://purl.uniprot.org/uniprot/Q0RFC0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS29590 ^@ http://purl.uniprot.org/uniprot/Q0RAY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04505 ^@ http://purl.uniprot.org/uniprot/Q0RRV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS02795 ^@ http://purl.uniprot.org/uniprot/Q0RSZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/326424:FRAAL_RS02915 ^@ http://purl.uniprot.org/uniprot/Q0RSW2 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/326424:FRAAL_RS09580 ^@ http://purl.uniprot.org/uniprot/Q0RNP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/326424:FRAAL_RS01970 ^@ http://purl.uniprot.org/uniprot/Q0RTI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS12510 ^@ http://purl.uniprot.org/uniprot/Q0RLU1 ^@ Domain|||Function|||Similarity|||Subunit ^@ ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.|||Belongs to the AAA ATPase family.|||Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.|||Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets. http://togogenome.org/gene/326424:FRAAL_RS04205 ^@ http://purl.uniprot.org/uniprot/Q0RS20 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/326424:FRAAL_RS19470 ^@ http://purl.uniprot.org/uniprot/Q0RHD6 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS18545 ^@ http://purl.uniprot.org/uniprot/Q0RHY8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/326424:FRAAL_RS02645 ^@ http://purl.uniprot.org/uniprot/Q0RT18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/326424:FRAAL_RS02130 ^@ http://purl.uniprot.org/uniprot/Q0RTD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6. http://togogenome.org/gene/326424:FRAAL_RS12290 ^@ http://purl.uniprot.org/uniprot/Q0RLY8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/326424:FRAAL_RS23115 ^@ http://purl.uniprot.org/uniprot/Q0RF17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/326424:FRAAL_RS22805 ^@ http://purl.uniprot.org/uniprot/Q0RF87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/326424:FRAAL_RS04780 ^@ http://purl.uniprot.org/uniprot/Q0RRQ3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS14570 ^@ http://purl.uniprot.org/uniprot/Q0RKH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.|||Cell membrane|||Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA). http://togogenome.org/gene/326424:FRAAL_RS08370 ^@ http://purl.uniprot.org/uniprot/Q0RPF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/326424:FRAAL_RS16850 ^@ http://purl.uniprot.org/uniprot/Q0RJ18 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04590 ^@ http://purl.uniprot.org/uniprot/Q0RRU1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/326424:FRAAL_RS15060 ^@ http://purl.uniprot.org/uniprot/Q0RK64 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/326424:FRAAL_RS05410 ^@ http://purl.uniprot.org/uniprot/Q0RRC1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/326424:FRAAL_RS14040 ^@ http://purl.uniprot.org/uniprot/Q0RKU9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS29880 ^@ http://purl.uniprot.org/uniprot/Q0RAS6 ^@ Function|||Similarity ^@ Belongs to the EgtB family.|||Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/326424:FRAAL_RS15195 ^@ http://purl.uniprot.org/uniprot/Q0RK33 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/326424:FRAAL_RS02200 ^@ http://purl.uniprot.org/uniprot/Q0RTB9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/326424:FRAAL_RS12685 ^@ http://purl.uniprot.org/uniprot/Q0RLQ3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS25320 ^@ http://purl.uniprot.org/uniprot/Q0RDM2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS01050 ^@ http://purl.uniprot.org/uniprot/Q0RU33 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/326424:FRAAL_RS15340 ^@ http://purl.uniprot.org/uniprot/Q0RK04 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04885 ^@ http://purl.uniprot.org/uniprot/Q0RRN2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS07935 ^@ http://purl.uniprot.org/uniprot/Q0RPP0 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS04225 ^@ http://purl.uniprot.org/uniprot/Q0RS16 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/326424:FRAAL_RS23035 ^@ http://purl.uniprot.org/uniprot/Q0RF35 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/326424:FRAAL_RS09620 ^@ http://purl.uniprot.org/uniprot/Q0RNN6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/326424:FRAAL_RS22175 ^@ http://purl.uniprot.org/uniprot/Q0RFL7 ^@ Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS29760 ^@ http://purl.uniprot.org/uniprot/Q0RAV3 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family.|||This protein is a Fe-Mo-cofactor biosynthetic component. http://togogenome.org/gene/326424:FRAAL_RS01390 ^@ http://purl.uniprot.org/uniprot/Q0RTV7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS10455 ^@ http://purl.uniprot.org/uniprot/Q0RN52 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/326424:FRAAL_RS19645 ^@ http://purl.uniprot.org/uniprot/Q0RH96 ^@ Function|||Similarity|||Subunit ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family.|||Homotrimer. http://togogenome.org/gene/326424:FRAAL_RS25375 ^@ http://purl.uniprot.org/uniprot/Q0RDK9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/326424:FRAAL_RS22820 ^@ http://purl.uniprot.org/uniprot/Q0RF84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/326424:FRAAL_RS08265 ^@ http://purl.uniprot.org/uniprot/Q0RPH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/326424:FRAAL_RS03060 ^@ http://purl.uniprot.org/uniprot/Q0RSS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS22170 ^@ http://purl.uniprot.org/uniprot/Q0RFL8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/326424:FRAAL_RS22770 ^@ http://purl.uniprot.org/uniprot/Q0RF94 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/326424:FRAAL_RS26960 ^@ http://purl.uniprot.org/uniprot/Q0RCM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS19630 ^@ http://purl.uniprot.org/uniprot/Q0RHA0 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||In the N-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/326424:FRAAL_RS23875 ^@ http://purl.uniprot.org/uniprot/Q0REJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS29735 ^@ http://purl.uniprot.org/uniprot/Q0RAV8 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/326424:FRAAL_RS15445 ^@ http://purl.uniprot.org/uniprot/Q0RJY1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS06355 ^@ http://purl.uniprot.org/uniprot/Q0RQQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homotetramer. http://togogenome.org/gene/326424:FRAAL_RS26555 ^@ http://purl.uniprot.org/uniprot/Q0RCW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/326424:FRAAL_RS27515 ^@ http://purl.uniprot.org/uniprot/Q0RC99 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/326424:FRAAL_RS27325 ^@ http://purl.uniprot.org/uniprot/Q0RCE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS21005 ^@ http://purl.uniprot.org/uniprot/Q0RGD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS34650 ^@ http://purl.uniprot.org/uniprot/Q0RQK4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS03875 ^@ http://purl.uniprot.org/uniprot/Q0RS91 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS00605 ^@ http://purl.uniprot.org/uniprot/Q0RUD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS08750 ^@ http://purl.uniprot.org/uniprot/Q0RP67 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS19965 ^@ http://purl.uniprot.org/uniprot/Q0RH26 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS30755 ^@ http://purl.uniprot.org/uniprot/Q0RCU9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/326424:FRAAL_RS04740 ^@ http://purl.uniprot.org/uniprot/Q0RRR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/326424:FRAAL_RS17610 ^@ http://purl.uniprot.org/uniprot/Q0RIK7 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/326424:FRAAL_RS25145 ^@ http://purl.uniprot.org/uniprot/Q0RDR2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/326424:FRAAL_RS26050 ^@ http://purl.uniprot.org/uniprot/Q0RD69 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/326424:FRAAL_RS17915 ^@ http://purl.uniprot.org/uniprot/Q0RID4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS29745 ^@ http://purl.uniprot.org/uniprot/Q0RAV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Binds 1 [8Fe-7S] cluster per heterodimer.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/326424:FRAAL_RS16485 ^@ http://purl.uniprot.org/uniprot/Q0RJA0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS05945 ^@ http://purl.uniprot.org/uniprot/Q0RR05 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/326424:FRAAL_RS19910 ^@ http://purl.uniprot.org/uniprot/Q0RH38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/326424:FRAAL_RS04620 ^@ http://purl.uniprot.org/uniprot/Q0RRT7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/326424:FRAAL_RS30045 ^@ http://purl.uniprot.org/uniprot/Q0RAP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of guanine in position 518 of 16S rRNA. http://togogenome.org/gene/326424:FRAAL_RS27055 ^@ http://purl.uniprot.org/uniprot/Q0RCJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS09560 ^@ http://purl.uniprot.org/uniprot/Q0RNP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/326424:FRAAL_RS29160 ^@ http://purl.uniprot.org/uniprot/Q0RB84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS06055 ^@ http://purl.uniprot.org/uniprot/Q0RQX6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS25840 ^@ http://purl.uniprot.org/uniprot/Q0RDB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/326424:FRAAL_RS13095 ^@ http://purl.uniprot.org/uniprot/Q0RLG1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS24020 ^@ http://purl.uniprot.org/uniprot/Q0REG3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS25515 ^@ http://purl.uniprot.org/uniprot/Q0RDI1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/326424:FRAAL_RS18290 ^@ http://purl.uniprot.org/uniprot/Q0RI44 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/326424:FRAAL_RS29575 ^@ http://purl.uniprot.org/uniprot/Q0RAZ1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS22675 ^@ http://purl.uniprot.org/uniprot/Q0RFB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS11420 ^@ http://purl.uniprot.org/uniprot/Q0RMI3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS19290 ^@ http://purl.uniprot.org/uniprot/Q0RHH4 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/326424:FRAAL_RS08260 ^@ http://purl.uniprot.org/uniprot/Q0RPH4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/326424:FRAAL_RS07270 ^@ http://purl.uniprot.org/uniprot/Q0RQ43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS29740 ^@ http://purl.uniprot.org/uniprot/Q0RAV7 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/326424:FRAAL_RS00815 ^@ http://purl.uniprot.org/uniprot/Q0RU88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS28030 ^@ http://purl.uniprot.org/uniprot/Q0RBY4 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/326424:FRAAL_RS29640 ^@ http://purl.uniprot.org/uniprot/Q0RAX7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS16565 ^@ http://purl.uniprot.org/uniprot/Q0RJ82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS13300 ^@ http://purl.uniprot.org/uniprot/Q0RLB8 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/326424:FRAAL_RS10835 ^@ http://purl.uniprot.org/uniprot/Q0RMW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25220 ^@ http://purl.uniprot.org/uniprot/Q0RDP7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/326424:FRAAL_RS16065 ^@ http://purl.uniprot.org/uniprot/Q0RJJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS28475 ^@ http://purl.uniprot.org/uniprot/Q0RBN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.|||Homooctamer.|||Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. http://togogenome.org/gene/326424:FRAAL_RS11000 ^@ http://purl.uniprot.org/uniprot/Q0RMT6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS10315 ^@ http://purl.uniprot.org/uniprot/Q0RN86 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/326424:FRAAL_RS04630 ^@ http://purl.uniprot.org/uniprot/Q0RRT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/326424:FRAAL_RS11475 ^@ http://purl.uniprot.org/uniprot/Q0RMH2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS04755 ^@ http://purl.uniprot.org/uniprot/Q0RRQ8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/326424:FRAAL_RS04355 ^@ http://purl.uniprot.org/uniprot/Q0RRY7 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/326424:FRAAL_RS29915 ^@ http://purl.uniprot.org/uniprot/Q0RAR7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/326424:FRAAL_RS22460 ^@ http://purl.uniprot.org/uniprot/Q0RFF4 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/326424:FRAAL_RS16785 ^@ http://purl.uniprot.org/uniprot/Q0RJ34 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/326424:FRAAL_RS05230 ^@ http://purl.uniprot.org/uniprot/Q0RRF8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/326424:FRAAL_RS28020 ^@ http://purl.uniprot.org/uniprot/Q0RBY6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS25885 ^@ http://purl.uniprot.org/uniprot/Q0RDA1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/326424:FRAAL_RS09015 ^@ http://purl.uniprot.org/uniprot/Q0RP11 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/326424:FRAAL_RS26230 ^@ http://purl.uniprot.org/uniprot/Q0RD28 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS14735 ^@ http://purl.uniprot.org/uniprot/Q0RKD8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS02650 ^@ http://purl.uniprot.org/uniprot/Q0RT17 ^@ Similarity ^@ Belongs to the DnaX/STICHEL family. http://togogenome.org/gene/326424:FRAAL_RS01495 ^@ http://purl.uniprot.org/uniprot/Q0RTT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS13805 ^@ http://purl.uniprot.org/uniprot/Q0RL01 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS31395 ^@ http://purl.uniprot.org/uniprot/Q0RQE7 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS23785 ^@ http://purl.uniprot.org/uniprot/Q0REL4 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/326424:FRAAL_RS25305 ^@ http://purl.uniprot.org/uniprot/Q0RDM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/326424:FRAAL_RS21090 ^@ http://purl.uniprot.org/uniprot/Q0RGB5 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS24300 ^@ http://purl.uniprot.org/uniprot/Q0RE98 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/326424:FRAAL_RS22485 ^@ http://purl.uniprot.org/uniprot/Q0RFE9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/326424:FRAAL_RS16765 ^@ http://purl.uniprot.org/uniprot/Q0RJ42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS16530 ^@ http://purl.uniprot.org/uniprot/Q0RJ90 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/326424:FRAAL_RS21120 ^@ http://purl.uniprot.org/uniprot/Q0RGA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS25095 ^@ http://purl.uniprot.org/uniprot/Q0RDS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/326424:FRAAL_RS03375 ^@ http://purl.uniprot.org/uniprot/Q0RSL0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/326424:FRAAL_RS06165 ^@ http://purl.uniprot.org/uniprot/Q0RQU9 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/326424:FRAAL_RS14845 ^@ http://purl.uniprot.org/uniprot/Q0RKB3 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/326424:FRAAL_RS06050 ^@ http://purl.uniprot.org/uniprot/Q0RQX7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS10540 ^@ http://purl.uniprot.org/uniprot/Q0RN32 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/326424:FRAAL_RS19300 ^@ http://purl.uniprot.org/uniprot/Q0RHH2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS24910 ^@ http://purl.uniprot.org/uniprot/Q0RDW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21260 ^@ http://purl.uniprot.org/uniprot/Q0RG75 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS23270 ^@ http://purl.uniprot.org/uniprot/Q0REY3 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/326424:FRAAL_RS13965 ^@ http://purl.uniprot.org/uniprot/Q0RKW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).|||Cytoplasm|||In the C-terminal section; belongs to the AccA family.|||In the N-terminal section; belongs to the AccD/PCCB family. http://togogenome.org/gene/326424:FRAAL_RS25235 ^@ http://purl.uniprot.org/uniprot/Q0RDP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/326424:FRAAL_RS24970 ^@ http://purl.uniprot.org/uniprot/Q0RDV0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS05235 ^@ http://purl.uniprot.org/uniprot/Q0RRF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. http://togogenome.org/gene/326424:FRAAL_RS21605 ^@ http://purl.uniprot.org/uniprot/Q0RFZ5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/326424:FRAAL_RS04880 ^@ http://purl.uniprot.org/uniprot/Q0RRN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/326424:FRAAL_RS23110 ^@ http://purl.uniprot.org/uniprot/Q0RF18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/326424:FRAAL_RS10440 ^@ http://purl.uniprot.org/uniprot/Q0RN55 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/326424:FRAAL_RS15740 ^@ http://purl.uniprot.org/uniprot/Q0RJR7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS19930 ^@ http://purl.uniprot.org/uniprot/Q0RH33 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/326424:FRAAL_RS13585 ^@ http://purl.uniprot.org/uniprot/Q0RL52 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS18375 ^@ http://purl.uniprot.org/uniprot/Q0RI28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS09375 ^@ http://purl.uniprot.org/uniprot/Q0RNT9 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/326424:FRAAL_RS13105 ^@ http://purl.uniprot.org/uniprot/Q0RLF8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS14890 ^@ http://purl.uniprot.org/uniprot/Q0RKA3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS28215 ^@ http://purl.uniprot.org/uniprot/Q0RBU0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS13215 ^@ http://purl.uniprot.org/uniprot/Q0RLD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the gas vesicle GvpA family.|||Gas vesicle shell|||Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.|||The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle. http://togogenome.org/gene/326424:FRAAL_RS14415 ^@ http://purl.uniprot.org/uniprot/Q0RKL5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS04000 ^@ http://purl.uniprot.org/uniprot/Q0RS64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS02925 ^@ http://purl.uniprot.org/uniprot/Q0RSW0 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/326424:FRAAL_RS20060 ^@ http://purl.uniprot.org/uniprot/Q0RH05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS07725 ^@ http://purl.uniprot.org/uniprot/Q0RPT5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/326424:FRAAL_RS21705 ^@ http://purl.uniprot.org/uniprot/Q0RFX5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS01750 ^@ http://purl.uniprot.org/uniprot/Q0RTN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS07355 ^@ http://purl.uniprot.org/uniprot/Q0RQ25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/326424:FRAAL_RS04375 ^@ http://purl.uniprot.org/uniprot/Q0RRY3 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/326424:FRAAL_RS04145 ^@ http://purl.uniprot.org/uniprot/Q0RS34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/326424:FRAAL_RS25055 ^@ http://purl.uniprot.org/uniprot/Q0RDT2 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/326424:FRAAL_RS20845 ^@ http://purl.uniprot.org/uniprot/Q0RGG7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS20935 ^@ http://purl.uniprot.org/uniprot/Q0RGE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS20055 ^@ http://purl.uniprot.org/uniprot/Q0RH06 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS29785 ^@ http://purl.uniprot.org/uniprot/Q0RAU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS29130 ^@ http://purl.uniprot.org/uniprot/Q0RB90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS11020 ^@ http://purl.uniprot.org/uniprot/Q0RMT1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS04855 ^@ http://purl.uniprot.org/uniprot/Q0RRN8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/326424:FRAAL_RS29675 ^@ http://purl.uniprot.org/uniprot/Q0RAX0 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/326424:FRAAL_RS22840 ^@ http://purl.uniprot.org/uniprot/Q0RF80 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/326424:FRAAL_RS12580 ^@ http://purl.uniprot.org/uniprot/Q0RLS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/326424:FRAAL_RS04425 ^@ http://purl.uniprot.org/uniprot/Q0RRX3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/326424:FRAAL_RS19635 ^@ http://purl.uniprot.org/uniprot/Q0RH98 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS04950 ^@ http://purl.uniprot.org/uniprot/Q0RRL8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/326424:FRAAL_RS04680 ^@ http://purl.uniprot.org/uniprot/Q0RRS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/326424:FRAAL_RS08395 ^@ http://purl.uniprot.org/uniprot/Q0RPE8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/326424:FRAAL_RS15670 ^@ http://purl.uniprot.org/uniprot/Q0RJT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS18840 ^@ http://purl.uniprot.org/uniprot/Q0RHR9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS18950 ^@ http://purl.uniprot.org/uniprot/Q70Z03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/326424:FRAAL_RS13740 ^@ http://purl.uniprot.org/uniprot/Q0RL16 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS29120 ^@ http://purl.uniprot.org/uniprot/Q0RB92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS25480 ^@ http://purl.uniprot.org/uniprot/Q0RDI8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. http://togogenome.org/gene/326424:FRAAL_RS28540 ^@ http://purl.uniprot.org/uniprot/Q0RBL9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/326424:FRAAL_RS14760 ^@ http://purl.uniprot.org/uniprot/Q0RKD3 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/326424:FRAAL_RS25855 ^@ http://purl.uniprot.org/uniprot/Q0RDA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. http://togogenome.org/gene/326424:FRAAL_RS18615 ^@ http://purl.uniprot.org/uniprot/Q0RHX4 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/326424:FRAAL_RS10190 ^@ http://purl.uniprot.org/uniprot/Q0RNB1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS15420 ^@ http://purl.uniprot.org/uniprot/Q0RJY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS01395 ^@ http://purl.uniprot.org/uniprot/Q0RTV6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS13760 ^@ http://purl.uniprot.org/uniprot/Q0RL12 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/326424:FRAAL_RS09520 ^@ http://purl.uniprot.org/uniprot/Q0RNQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/326424:FRAAL_RS22830 ^@ http://purl.uniprot.org/uniprot/Q0RF82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS13690 ^@ http://purl.uniprot.org/uniprot/Q0RL28 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS26725 ^@ http://purl.uniprot.org/uniprot/Q0RCS3 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/326424:FRAAL_RS22670 ^@ http://purl.uniprot.org/uniprot/Q0RFB4 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/326424:FRAAL_RS01705 ^@ http://purl.uniprot.org/uniprot/Q0RTP2 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/326424:FRAAL_RS28375 ^@ http://purl.uniprot.org/uniprot/Q0RBQ4 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/326424:FRAAL_RS16755 ^@ http://purl.uniprot.org/uniprot/Q0RJ44 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS25015 ^@ http://purl.uniprot.org/uniprot/Q0RDU0 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS10955 ^@ http://purl.uniprot.org/uniprot/Q0RMU5 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/326424:FRAAL_RS00335 ^@ http://purl.uniprot.org/uniprot/Q0RUI8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS01560 ^@ http://purl.uniprot.org/uniprot/Q0RTS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS00125 ^@ http://purl.uniprot.org/uniprot/Q0RUN7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/326424:FRAAL_RS25915 ^@ http://purl.uniprot.org/uniprot/Q0RD95 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS22510 ^@ http://purl.uniprot.org/uniprot/Q0RFE4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/326424:FRAAL_RS23810 ^@ http://purl.uniprot.org/uniprot/Q0REK8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS19420 ^@ http://purl.uniprot.org/uniprot/Q0RHE6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS13325 ^@ http://purl.uniprot.org/uniprot/Q0RLB3 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/326424:FRAAL_RS16505 ^@ http://purl.uniprot.org/uniprot/Q0RJ96 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/326424:FRAAL_RS27170 ^@ http://purl.uniprot.org/uniprot/Q0RCH4 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS28985 ^@ http://purl.uniprot.org/uniprot/Q0RBC2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/326424:FRAAL_RS14225 ^@ http://purl.uniprot.org/uniprot/Q0RKQ8 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/326424:FRAAL_RS21115 ^@ http://purl.uniprot.org/uniprot/Q0RGB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS27485 ^@ http://purl.uniprot.org/uniprot/Q0RCA5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/326424:FRAAL_RS05565 ^@ http://purl.uniprot.org/uniprot/Q0RR88 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/326424:FRAAL_RS26980 ^@ http://purl.uniprot.org/uniprot/Q0RCL6 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS00900 ^@ http://purl.uniprot.org/uniprot/Q0RU70 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS22815 ^@ http://purl.uniprot.org/uniprot/Q0RF85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/326424:FRAAL_RS26760 ^@ http://purl.uniprot.org/uniprot/Q0RCR5 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/326424:FRAAL_RS07980 ^@ http://purl.uniprot.org/uniprot/Q0RPN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS19680 ^@ http://purl.uniprot.org/uniprot/Q0RH88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/326424:FRAAL_RS08105 ^@ http://purl.uniprot.org/uniprot/Q0RPK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS06135 ^@ http://purl.uniprot.org/uniprot/Q0RQV5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS00915 ^@ http://purl.uniprot.org/uniprot/Q0RU67 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS29115 ^@ http://purl.uniprot.org/uniprot/Q0RB93 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/326424:FRAAL_RS19475 ^@ http://purl.uniprot.org/uniprot/Q0RHD5 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS25185 ^@ http://purl.uniprot.org/uniprot/Q0RDQ4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/326424:FRAAL_RS30285 ^@ http://purl.uniprot.org/uniprot/Q0RPE1 ^@ Similarity ^@ Belongs to the ice-binding protein family. http://togogenome.org/gene/326424:FRAAL_RS22220 ^@ http://purl.uniprot.org/uniprot/Q0RFK8 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/326424:FRAAL_RS02605 ^@ http://purl.uniprot.org/uniprot/Q0RT26 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21595 ^@ http://purl.uniprot.org/uniprot/Q0RFZ7 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/326424:FRAAL_RS24525 ^@ http://purl.uniprot.org/uniprot/Q0RE47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25870 ^@ http://purl.uniprot.org/uniprot/Q0RDA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS15115 ^@ http://purl.uniprot.org/uniprot/Q0RK51 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS00055 ^@ http://purl.uniprot.org/uniprot/Q0RUQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/326424:FRAAL_RS15695 ^@ http://purl.uniprot.org/uniprot/Q0RJS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS07865 ^@ http://purl.uniprot.org/uniprot/Q0RPQ5 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/326424:FRAAL_RS18830 ^@ http://purl.uniprot.org/uniprot/Q0RHS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/326424:FRAAL_RS15525 ^@ http://purl.uniprot.org/uniprot/Q0RJW5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS29240 ^@ http://purl.uniprot.org/uniprot/Q0RB68 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/326424:FRAAL_RS09600 ^@ http://purl.uniprot.org/uniprot/Q0RNP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/326424:FRAAL_RS26490 ^@ http://purl.uniprot.org/uniprot/Q0RCX7 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/326424:FRAAL_RS00385 ^@ http://purl.uniprot.org/uniprot/Q0RUH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS21550 ^@ http://purl.uniprot.org/uniprot/Q0RG08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS16090 ^@ http://purl.uniprot.org/uniprot/Q0RJI7 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS04700 ^@ http://purl.uniprot.org/uniprot/Q0RRR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/326424:FRAAL_RS28470 ^@ http://purl.uniprot.org/uniprot/Q0RBN3 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/326424:FRAAL_RS13860 ^@ http://purl.uniprot.org/uniprot/Q0RKY7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/326424:FRAAL_RS29100 ^@ http://purl.uniprot.org/uniprot/Q0RB96 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/326424:FRAAL_RS27845 ^@ http://purl.uniprot.org/uniprot/Q0RC25 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS24435 ^@ http://purl.uniprot.org/uniprot/Q0RE66 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/326424:FRAAL_RS13200 ^@ http://purl.uniprot.org/uniprot/Q0RLD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle GvpF/GvpL family.|||Gas vesicle|||Vesicle http://togogenome.org/gene/326424:FRAAL_RS08210 ^@ http://purl.uniprot.org/uniprot/Q0RPI2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS13150 ^@ http://purl.uniprot.org/uniprot/Q0RLE9 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/326424:FRAAL_RS06805 ^@ http://purl.uniprot.org/uniprot/Q0RQF1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04675 ^@ http://purl.uniprot.org/uniprot/Q0RRS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS26750 ^@ http://purl.uniprot.org/uniprot/Q0RCR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS30685 ^@ http://purl.uniprot.org/uniprot/Q0REJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS22890 ^@ http://purl.uniprot.org/uniprot/Q0RF70 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/326424:FRAAL_RS20540 ^@ http://purl.uniprot.org/uniprot/Q0RGN3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS25125 ^@ http://purl.uniprot.org/uniprot/Q0RDR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS12965 ^@ http://purl.uniprot.org/uniprot/Q0RLJ0 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/326424:FRAAL_RS22115 ^@ http://purl.uniprot.org/uniprot/Q0RFM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS11450 ^@ http://purl.uniprot.org/uniprot/Q0RMH7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS24945 ^@ http://purl.uniprot.org/uniprot/Q0RDV6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/326424:FRAAL_RS25070 ^@ http://purl.uniprot.org/uniprot/Q0RDS9 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/326424:FRAAL_RS10375 ^@ http://purl.uniprot.org/uniprot/Q0RN74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS05970 ^@ http://purl.uniprot.org/uniprot/Q0RR00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/326424:FRAAL_RS26715 ^@ http://purl.uniprot.org/uniprot/Q0RCS5 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/326424:FRAAL_RS24175 ^@ http://purl.uniprot.org/uniprot/Q0RED0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS13290 ^@ http://purl.uniprot.org/uniprot/Q0RLC0 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS11180 ^@ http://purl.uniprot.org/uniprot/Q0RMP2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS25255 ^@ http://purl.uniprot.org/uniprot/Q0RDP1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/326424:FRAAL_RS13565 ^@ http://purl.uniprot.org/uniprot/Q0RL56 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS25875 ^@ http://purl.uniprot.org/uniprot/Q0RDA3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS33930 ^@ http://purl.uniprot.org/uniprot/Q0RTP3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS06270 ^@ http://purl.uniprot.org/uniprot/Q0RQS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/326424:FRAAL_RS06910 ^@ http://purl.uniprot.org/uniprot/Q0RQC5 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/326424:FRAAL_RS06815 ^@ http://purl.uniprot.org/uniprot/Q0RQE9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS06400 ^@ http://purl.uniprot.org/uniprot/Q0RQP8 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/326424:FRAAL_RS26485 ^@ http://purl.uniprot.org/uniprot/Q0RCX8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS01570 ^@ http://purl.uniprot.org/uniprot/Q0RTR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS19950 ^@ http://purl.uniprot.org/uniprot/Q0RH29 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/326424:FRAAL_RS27135 ^@ http://purl.uniprot.org/uniprot/Q0RCI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS25075 ^@ http://purl.uniprot.org/uniprot/Q0RDS8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/326424:FRAAL_RS27910 ^@ http://purl.uniprot.org/uniprot/Q0RC11 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/326424:FRAAL_RS27200 ^@ http://purl.uniprot.org/uniprot/Q0RCG7 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/326424:FRAAL_RS26270 ^@ http://purl.uniprot.org/uniprot/Q0RD21 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/326424:FRAAL_RS00945 ^@ http://purl.uniprot.org/uniprot/Q0RU60 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/326424:FRAAL_RS29545 ^@ http://purl.uniprot.org/uniprot/Q0RB00 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/326424:FRAAL_RS13835 ^@ http://purl.uniprot.org/uniprot/Q0RKZ4 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/326424:FRAAL_RS11440 ^@ http://purl.uniprot.org/uniprot/Q0RMH9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS26705 ^@ http://purl.uniprot.org/uniprot/Q0RCS7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/326424:FRAAL_RS22405 ^@ http://purl.uniprot.org/uniprot/Q0RFG5 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/326424:FRAAL_RS00885 ^@ http://purl.uniprot.org/uniprot/Q0RU73 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS07145 ^@ http://purl.uniprot.org/uniprot/Q0RQ69 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/326424:FRAAL_RS26965 ^@ http://purl.uniprot.org/uniprot/Q0RCL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS09365 ^@ http://purl.uniprot.org/uniprot/Q0RNU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS20800 ^@ http://purl.uniprot.org/uniprot/Q0RGH7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS09585 ^@ http://purl.uniprot.org/uniprot/Q0RNP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS10355 ^@ http://purl.uniprot.org/uniprot/Q0RN78 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS07605 ^@ http://purl.uniprot.org/uniprot/Q0RPW1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/326424:FRAAL_RS24930 ^@ http://purl.uniprot.org/uniprot/Q0RDW1 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/326424:FRAAL_RS21190 ^@ http://purl.uniprot.org/uniprot/Q0RG92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Belongs to the glycosyltransferase 2 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS10620 ^@ http://purl.uniprot.org/uniprot/Q0RN11 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/326424:FRAAL_RS04560 ^@ http://purl.uniprot.org/uniprot/Q0RRU5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS25240 ^@ http://purl.uniprot.org/uniprot/Q0RDP3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein uS19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein uS19. http://togogenome.org/gene/326424:FRAAL_RS26745 ^@ http://purl.uniprot.org/uniprot/Q0RCR9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MshB deacetylase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. http://togogenome.org/gene/326424:FRAAL_RS22515 ^@ http://purl.uniprot.org/uniprot/Q0RFE2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/326424:FRAAL_RS02415 ^@ http://purl.uniprot.org/uniprot/Q0RT71 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/326424:FRAAL_RS25910 ^@ http://purl.uniprot.org/uniprot/Q0RD96 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/326424:FRAAL_RS26605 ^@ http://purl.uniprot.org/uniprot/Q0RCV1 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/326424:FRAAL_RS08150 ^@ http://purl.uniprot.org/uniprot/Q0RPJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25175 ^@ http://purl.uniprot.org/uniprot/Q0RDQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/326424:FRAAL_RS02860 ^@ http://purl.uniprot.org/uniprot/Q0RSX4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/326424:FRAAL_RS09230 ^@ http://purl.uniprot.org/uniprot/Q0RNW7 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/326424:FRAAL_RS15655 ^@ http://purl.uniprot.org/uniprot/Q0RJT4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/326424:FRAAL_RS12555 ^@ http://purl.uniprot.org/uniprot/Q0RLT2 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/326424:FRAAL_RS04470 ^@ http://purl.uniprot.org/uniprot/Q0RRW3 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/326424:FRAAL_RS16685 ^@ http://purl.uniprot.org/uniprot/Q0RJ58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04925 ^@ http://purl.uniprot.org/uniprot/Q0RRM3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/326424:FRAAL_RS09085 ^@ http://purl.uniprot.org/uniprot/Q0RNZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS29965 ^@ http://purl.uniprot.org/uniprot/Q0RAQ7 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/326424:FRAAL_RS23120 ^@ http://purl.uniprot.org/uniprot/Q0RF16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/326424:FRAAL_RS28280 ^@ http://purl.uniprot.org/uniprot/Q0RBS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/326424:FRAAL_RS09555 ^@ http://purl.uniprot.org/uniprot/Q0RNQ0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/326424:FRAAL_RS06290 ^@ http://purl.uniprot.org/uniprot/Q0RQS0 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/326424:FRAAL_RS17955 ^@ http://purl.uniprot.org/uniprot/Q0RIC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS14120 ^@ http://purl.uniprot.org/uniprot/Q0RKT3 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/326424:FRAAL_RS13090 ^@ http://purl.uniprot.org/uniprot/Q0RLG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04685 ^@ http://purl.uniprot.org/uniprot/Q0RRS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS18140 ^@ http://purl.uniprot.org/uniprot/Q0RI82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS21710 ^@ http://purl.uniprot.org/uniprot/Q0RFX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS10950 ^@ http://purl.uniprot.org/uniprot/Q0RMU6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/326424:FRAAL_RS25295 ^@ http://purl.uniprot.org/uniprot/Q0RDM9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS25475 ^@ http://purl.uniprot.org/uniprot/Q0RDI9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/326424:FRAAL_RS21215 ^@ http://purl.uniprot.org/uniprot/Q0RG85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS24640 ^@ http://purl.uniprot.org/uniprot/Q0RE21 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/326424:FRAAL_RS12630 ^@ http://purl.uniprot.org/uniprot/Q0RLR6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS14070 ^@ http://purl.uniprot.org/uniprot/Q0RKU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial phospholipase C family.|||cell wall http://togogenome.org/gene/326424:FRAAL_RS13770 ^@ http://purl.uniprot.org/uniprot/Q0RL10 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/326424:FRAAL_RS25610 ^@ http://purl.uniprot.org/uniprot/Q0RDG2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS25995 ^@ http://purl.uniprot.org/uniprot/Q0RD80 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS02585 ^@ http://purl.uniprot.org/uniprot/Q0RT30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS25710 ^@ http://purl.uniprot.org/uniprot/Q0RDD9 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/326424:FRAAL_RS26390 ^@ http://purl.uniprot.org/uniprot/Q0RCZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/326424:FRAAL_RS04815 ^@ http://purl.uniprot.org/uniprot/Q0RRP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/326424:FRAAL_RS20740 ^@ http://purl.uniprot.org/uniprot/Q0RGJ0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS24905 ^@ http://purl.uniprot.org/uniprot/Q0RDW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/326424:FRAAL_RS05335 ^@ http://purl.uniprot.org/uniprot/Q0RRD6 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS14675 ^@ http://purl.uniprot.org/uniprot/Q0RKF1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS04790 ^@ http://purl.uniprot.org/uniprot/Q0RRQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/326424:FRAAL_RS19870 ^@ http://purl.uniprot.org/uniprot/Q0RH48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS14915 ^@ http://purl.uniprot.org/uniprot/Q0RK96 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS21300 ^@ http://purl.uniprot.org/uniprot/Q0RG66 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS29835 ^@ http://purl.uniprot.org/uniprot/Q0RAT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Cell membrane|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/326424:FRAAL_RS19745 ^@ http://purl.uniprot.org/uniprot/Q0RH75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III. http://togogenome.org/gene/326424:FRAAL_RS20790 ^@ http://purl.uniprot.org/uniprot/Q0RGH9 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS25430 ^@ http://purl.uniprot.org/uniprot/Q0RDJ9 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/326424:FRAAL_RS15345 ^@ http://purl.uniprot.org/uniprot/Q0RK03 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04800 ^@ http://purl.uniprot.org/uniprot/Q0RRP9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/326424:FRAAL_RS16690 ^@ http://purl.uniprot.org/uniprot/Q0RJ57 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/326424:FRAAL_RS04690 ^@ http://purl.uniprot.org/uniprot/Q0RRS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/326424:FRAAL_RS25100 ^@ http://purl.uniprot.org/uniprot/Q0RDS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/326424:FRAAL_RS19285 ^@ http://purl.uniprot.org/uniprot/Q0RHH6 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/326424:FRAAL_RS06415 ^@ http://purl.uniprot.org/uniprot/Q0RQP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/326424:FRAAL_RS16905 ^@ http://purl.uniprot.org/uniprot/Q0RJ07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS10960 ^@ http://purl.uniprot.org/uniprot/Q0RMU4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS00080 ^@ http://purl.uniprot.org/uniprot/Q0RUP1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/326424:FRAAL_RS21545 ^@ http://purl.uniprot.org/uniprot/Q0RG09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17485 ^@ http://purl.uniprot.org/uniprot/Q0RIN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS18850 ^@ http://purl.uniprot.org/uniprot/Q0RHR7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/326424:FRAAL_RS09300 ^@ http://purl.uniprot.org/uniprot/Q0RNV5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS25760 ^@ http://purl.uniprot.org/uniprot/Q0RDC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS09790 ^@ http://purl.uniprot.org/uniprot/Q0RNJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS11405 ^@ http://purl.uniprot.org/uniprot/Q0RMI6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS20525 ^@ http://purl.uniprot.org/uniprot/Q0RGN6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS04795 ^@ http://purl.uniprot.org/uniprot/Q0RRQ0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS15980 ^@ http://purl.uniprot.org/uniprot/Q0RJL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17450 ^@ http://purl.uniprot.org/uniprot/Q0RIP3 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/326424:FRAAL_RS18390 ^@ http://purl.uniprot.org/uniprot/Q0RI24 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS18205 ^@ http://purl.uniprot.org/uniprot/Q0RI66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS12585 ^@ http://purl.uniprot.org/uniprot/Q0RLS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/326424:FRAAL_RS08700 ^@ http://purl.uniprot.org/uniprot/Q0RP78 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/326424:FRAAL_RS26780 ^@ http://purl.uniprot.org/uniprot/Q0RCR0 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/326424:FRAAL_RS22545 ^@ http://purl.uniprot.org/uniprot/Q0RFD5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/326424:FRAAL_RS01500 ^@ http://purl.uniprot.org/uniprot/Q0RTT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS08590 ^@ http://purl.uniprot.org/uniprot/Q0RPA1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS18430 ^@ http://purl.uniprot.org/uniprot/Q0RI14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS04640 ^@ http://purl.uniprot.org/uniprot/Q0RRT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/326424:FRAAL_RS20455 ^@ http://purl.uniprot.org/uniprot/Q0RGQ6 ^@ Similarity ^@ Belongs to the clavaminate synthase family. http://togogenome.org/gene/326424:FRAAL_RS15840 ^@ http://purl.uniprot.org/uniprot/Q0RJP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17180 ^@ http://purl.uniprot.org/uniprot/Q0RIU9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS28805 ^@ http://purl.uniprot.org/uniprot/Q0RBG4 ^@ Similarity|||Subunit ^@ Belongs to the Bpa family.|||Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings. http://togogenome.org/gene/326424:FRAAL_RS06475 ^@ http://purl.uniprot.org/uniprot/Q0RQN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS20135 ^@ http://purl.uniprot.org/uniprot/Q0RGY7 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/326424:FRAAL_RS27010 ^@ http://purl.uniprot.org/uniprot/Q0RCK9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS09040 ^@ http://purl.uniprot.org/uniprot/Q0RP06 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/326424:FRAAL_RS25385 ^@ http://purl.uniprot.org/uniprot/Q0RDK7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/326424:FRAAL_RS04835 ^@ http://purl.uniprot.org/uniprot/Q0RRP2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/326424:FRAAL_RS09345 ^@ http://purl.uniprot.org/uniprot/Q0RNU6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvB family.|||Cytoplasm|||Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.|||Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA. http://togogenome.org/gene/326424:FRAAL_RS20080 ^@ http://purl.uniprot.org/uniprot/Q0RH00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/326424:FRAAL_RS18720 ^@ http://purl.uniprot.org/uniprot/Q0RHU8 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/326424:FRAAL_RS15570 ^@ http://purl.uniprot.org/uniprot/Q0RJV6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS07840 ^@ http://purl.uniprot.org/uniprot/Q0RPR1 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/326424:FRAAL_RS14155 ^@ http://purl.uniprot.org/uniprot/Q0RKS5 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/326424:FRAAL_RS06690 ^@ http://purl.uniprot.org/uniprot/Q0RQI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/326424:FRAAL_RS10010 ^@ http://purl.uniprot.org/uniprot/Q0RNE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS14410 ^@ http://purl.uniprot.org/uniprot/Q0RKL6 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/326424:FRAAL_RS20045 ^@ http://purl.uniprot.org/uniprot/Q0RH09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS17840 ^@ http://purl.uniprot.org/uniprot/Q0RIF4 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/326424:FRAAL_RS09495 ^@ http://purl.uniprot.org/uniprot/Q0RNR3 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/326424:FRAAL_RS05245 ^@ http://purl.uniprot.org/uniprot/Q0RRF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS24320 ^@ http://purl.uniprot.org/uniprot/Q0RE94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/326424:FRAAL_RS21195 ^@ http://purl.uniprot.org/uniprot/Q0RG91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17630 ^@ http://purl.uniprot.org/uniprot/Q0RIK2 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/326424:FRAAL_RS21530 ^@ http://purl.uniprot.org/uniprot/Q0RG14 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS23190 ^@ http://purl.uniprot.org/uniprot/Q0RF00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS29005 ^@ http://purl.uniprot.org/uniprot/Q0RBB8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/326424:FRAAL_RS00355 ^@ http://purl.uniprot.org/uniprot/Q0RUI4 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/326424:FRAAL_RS06205 ^@ http://purl.uniprot.org/uniprot/Q0RQU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS26550 ^@ http://purl.uniprot.org/uniprot/Q0RCW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/326424:FRAAL_RS29405 ^@ http://purl.uniprot.org/uniprot/Q0RB30 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/326424:FRAAL_RS09330 ^@ http://purl.uniprot.org/uniprot/Q0RNU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS14935 ^@ http://purl.uniprot.org/uniprot/Q0RK92 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS29885 ^@ http://purl.uniprot.org/uniprot/Q0RAS5 ^@ Function ^@ Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/326424:FRAAL_RS07325 ^@ http://purl.uniprot.org/uniprot/Q0RQ32 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/326424:FRAAL_RS29710 ^@ http://purl.uniprot.org/uniprot/Q0RAW3 ^@ Similarity ^@ Belongs to the NifZ family. http://togogenome.org/gene/326424:FRAAL_RS04725 ^@ http://purl.uniprot.org/uniprot/Q0RRR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS20815 ^@ http://purl.uniprot.org/uniprot/Q0RGH4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS09070 ^@ http://purl.uniprot.org/uniprot/Q0RP00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS09940 ^@ http://purl.uniprot.org/uniprot/Q0RNG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS06085 ^@ http://purl.uniprot.org/uniprot/Q0RQW9 ^@ Similarity ^@ Belongs to the bacterial lectin family. http://togogenome.org/gene/326424:FRAAL_RS28320 ^@ http://purl.uniprot.org/uniprot/Q0RBR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/326424:FRAAL_RS25285 ^@ http://purl.uniprot.org/uniprot/Q0RDN2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS01900 ^@ http://purl.uniprot.org/uniprot/Q0RTK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS28755 ^@ http://purl.uniprot.org/uniprot/Q0RBH5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS09325 ^@ http://purl.uniprot.org/uniprot/Q0RNV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/326424:FRAAL_RS22690 ^@ http://purl.uniprot.org/uniprot/Q0RFB0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS27420 ^@ http://purl.uniprot.org/uniprot/Q0RCC0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/326424:FRAAL_RS21610 ^@ http://purl.uniprot.org/uniprot/Q0RFZ4 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/326424:FRAAL_RS02615 ^@ http://purl.uniprot.org/uniprot/Q0RT24 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/326424:FRAAL_RS24565 ^@ http://purl.uniprot.org/uniprot/Q0RE36 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/326424:FRAAL_RS13890 ^@ http://purl.uniprot.org/uniprot/Q0RKY0 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/326424:FRAAL_RS08405 ^@ http://purl.uniprot.org/uniprot/Q0RPE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein uL14 (rplN). http://togogenome.org/gene/326424:FRAAL_RS12535 ^@ http://purl.uniprot.org/uniprot/Q0RLT6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/326424:FRAAL_RS22790 ^@ http://purl.uniprot.org/uniprot/Q0RF90 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/326424:FRAAL_RS09335 ^@ http://purl.uniprot.org/uniprot/Q0RNU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvC family.|||Binds 2 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/326424:FRAAL_RS08280 ^@ http://purl.uniprot.org/uniprot/Q0RPH0 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/326424:FRAAL_RS04750 ^@ http://purl.uniprot.org/uniprot/Q0RRQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/326424:FRAAL_RS05525 ^@ http://purl.uniprot.org/uniprot/Q0RR96 ^@ Function|||Similarity ^@ Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.|||In the C-terminal section; belongs to the radical SAM superfamily. CofH family.|||In the N-terminal section; belongs to the radical SAM superfamily. CofG family. http://togogenome.org/gene/326424:FRAAL_RS22745 ^@ http://purl.uniprot.org/uniprot/Q0RF99 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/326424:FRAAL_RS04495 ^@ http://purl.uniprot.org/uniprot/Q0RRV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS12610 ^@ http://purl.uniprot.org/uniprot/Q0RLS0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS13870 ^@ http://purl.uniprot.org/uniprot/Q0RKY5 ^@ Function|||Similarity ^@ A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).|||Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily. http://togogenome.org/gene/326424:FRAAL_RS02320 ^@ http://purl.uniprot.org/uniprot/Q0RT91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS08945 ^@ http://purl.uniprot.org/uniprot/Q0RP27 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS14900 ^@ http://purl.uniprot.org/uniprot/Q0RK99 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/326424:FRAAL_RS19100 ^@ http://purl.uniprot.org/uniprot/Q0RHL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS16800 ^@ http://purl.uniprot.org/uniprot/Q0RJ31 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS07810 ^@ http://purl.uniprot.org/uniprot/Q0RPR8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/326424:FRAAL_RS14775 ^@ http://purl.uniprot.org/uniprot/Q0RKD0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04710 ^@ http://purl.uniprot.org/uniprot/Q0RRR7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/326424:FRAAL_RS13920 ^@ http://purl.uniprot.org/uniprot/Q0RKX4 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/326424:FRAAL_RS29715 ^@ http://purl.uniprot.org/uniprot/Q0RAW2|||http://purl.uniprot.org/uniprot/Q2TT19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifW family.|||Homotrimer; associates with NifD.|||May protect the nitrogenase Fe-Mo protein from oxidative damage. http://togogenome.org/gene/326424:FRAAL_RS07500 ^@ http://purl.uniprot.org/uniprot/Q0RPY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS27415 ^@ http://purl.uniprot.org/uniprot/Q0RCC1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS06845 ^@ http://purl.uniprot.org/uniprot/Q0RQD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04665 ^@ http://purl.uniprot.org/uniprot/Q0RRS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/326424:FRAAL_RS14920 ^@ http://purl.uniprot.org/uniprot/Q0RK95 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS05790 ^@ http://purl.uniprot.org/uniprot/Q0RR41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS26260 ^@ http://purl.uniprot.org/uniprot/Q0RD23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS01480 ^@ http://purl.uniprot.org/uniprot/Q0RTT8 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/326424:FRAAL_RS25850 ^@ http://purl.uniprot.org/uniprot/Q0RDA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS22600 ^@ http://purl.uniprot.org/uniprot/Q0RFC4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS25250 ^@ http://purl.uniprot.org/uniprot/Q0RDP2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/326424:FRAAL_RS10040 ^@ http://purl.uniprot.org/uniprot/Q0RNE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS09590 ^@ http://purl.uniprot.org/uniprot/Q0RNP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS06410 ^@ http://purl.uniprot.org/uniprot/Q0RQP6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS04635 ^@ http://purl.uniprot.org/uniprot/Q0RRT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/326424:FRAAL_RS03325 ^@ http://purl.uniprot.org/uniprot/Q0RSL9 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/326424:FRAAL_RS29085 ^@ http://purl.uniprot.org/uniprot/Q0RBA0 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/326424:FRAAL_RS06970 ^@ http://purl.uniprot.org/uniprot/Q0RQA8 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/326424:FRAAL_RS16540 ^@ http://purl.uniprot.org/uniprot/Q0RJ88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04970 ^@ http://purl.uniprot.org/uniprot/Q0RRL4 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/326424:FRAAL_RS08205 ^@ http://purl.uniprot.org/uniprot/Q0RPI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS28995 ^@ http://purl.uniprot.org/uniprot/Q0RBC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/326424:FRAAL_RS25770 ^@ http://purl.uniprot.org/uniprot/Q0RDC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS29365 ^@ http://purl.uniprot.org/uniprot/Q0RB38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS28975 ^@ http://purl.uniprot.org/uniprot/Q0RBC4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/326424:FRAAL_RS04760 ^@ http://purl.uniprot.org/uniprot/Q0RRQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/326424:FRAAL_RS24935 ^@ http://purl.uniprot.org/uniprot/Q0RDW0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/326424:FRAAL_RS17885 ^@ http://purl.uniprot.org/uniprot/Q0RIE3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/326424:FRAAL_RS25260 ^@ http://purl.uniprot.org/uniprot/Q0RDN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/326424:FRAAL_RS23795 ^@ http://purl.uniprot.org/uniprot/Q0REL2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/326424:FRAAL_RS04910 ^@ http://purl.uniprot.org/uniprot/Q0RRM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/326424:FRAAL_RS07220 ^@ http://purl.uniprot.org/uniprot/Q0RQ53 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS30060 ^@ http://purl.uniprot.org/uniprot/Q0RAN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/326424:FRAAL_RS14395 ^@ http://purl.uniprot.org/uniprot/Q0RKL9 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/326424:FRAAL_RS06190 ^@ http://purl.uniprot.org/uniprot/Q0RQU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS09010 ^@ http://purl.uniprot.org/uniprot/Q0RP12 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/326424:FRAAL_RS25535 ^@ http://purl.uniprot.org/uniprot/Q0RDH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS02570 ^@ http://purl.uniprot.org/uniprot/Q0RT34 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/326424:FRAAL_RS17310 ^@ http://purl.uniprot.org/uniprot/Q0RIS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS06865 ^@ http://purl.uniprot.org/uniprot/Q0RQD5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS12285 ^@ http://purl.uniprot.org/uniprot/Q0RLY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS17405 ^@ http://purl.uniprot.org/uniprot/Q0RIQ2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS20020 ^@ http://purl.uniprot.org/uniprot/Q0RH15 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/326424:FRAAL_RS03995 ^@ http://purl.uniprot.org/uniprot/Q0RS65 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/326424:FRAAL_RS06555 ^@ http://purl.uniprot.org/uniprot/Q0RQL3 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/326424:FRAAL_RS07015 ^@ http://purl.uniprot.org/uniprot/Q0RQ99 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS07385 ^@ http://purl.uniprot.org/uniprot/Q0RQ19 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/326424:FRAAL_RS29635 ^@ http://purl.uniprot.org/uniprot/Q0RAX8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS24960 ^@ http://purl.uniprot.org/uniprot/Q0RDV2 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/326424:FRAAL_RS01510 ^@ http://purl.uniprot.org/uniprot/Q0RTT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS07065 ^@ http://purl.uniprot.org/uniprot/Q0RQ87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS10660 ^@ http://purl.uniprot.org/uniprot/Q0RN02 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/326424:FRAAL_RS21665 ^@ http://purl.uniprot.org/uniprot/Q0RFY3 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/326424:FRAAL_RS16825 ^@ http://purl.uniprot.org/uniprot/Q0RJ24 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS20685 ^@ http://purl.uniprot.org/uniprot/Q0RGK2 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/326424:FRAAL_RS22885 ^@ http://purl.uniprot.org/uniprot/Q0RF71 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS01595 ^@ http://purl.uniprot.org/uniprot/Q0RTR4 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS25485 ^@ http://purl.uniprot.org/uniprot/Q0RDI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/326424:FRAAL_RS04510 ^@ http://purl.uniprot.org/uniprot/Q0RRV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS06965 ^@ http://purl.uniprot.org/uniprot/Q0RQA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS25525 ^@ http://purl.uniprot.org/uniprot/Q0RDH8 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/326424:FRAAL_RS09885 ^@ http://purl.uniprot.org/uniprot/Q0RNH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS24615 ^@ http://purl.uniprot.org/uniprot/Q0RE26 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/326424:FRAAL_RS08350 ^@ http://purl.uniprot.org/uniprot/Q0RPF7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/326424:FRAAL_RS00490 ^@ http://purl.uniprot.org/uniprot/Q0RUF8 ^@ Cofactor|||Similarity ^@ Belongs to the DNA photolyase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/326424:FRAAL_RS11220 ^@ http://purl.uniprot.org/uniprot/Q0RMN4 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/326424:FRAAL_RS09140 ^@ http://purl.uniprot.org/uniprot/Q0RNY6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS14905 ^@ http://purl.uniprot.org/uniprot/Q0RK98 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS15995 ^@ http://purl.uniprot.org/uniprot/Q0RJK8 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/326424:FRAAL_RS28950 ^@ http://purl.uniprot.org/uniprot/Q0RBD0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/326424:FRAAL_RS20260 ^@ http://purl.uniprot.org/uniprot/Q0RGV4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/326424:FRAAL_RS23495 ^@ http://purl.uniprot.org/uniprot/Q0RET5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS28740 ^@ http://purl.uniprot.org/uniprot/Q0RBH8 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/326424:FRAAL_RS08760 ^@ http://purl.uniprot.org/uniprot/Q0RP65 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/326424:FRAAL_RS16610 ^@ http://purl.uniprot.org/uniprot/Q0RJ73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS00520 ^@ http://purl.uniprot.org/uniprot/Q0RUF1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/326424:FRAAL_RS04245 ^@ http://purl.uniprot.org/uniprot/Q0RS11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS21985 ^@ http://purl.uniprot.org/uniprot/Q0RFQ7 ^@ Similarity ^@ Belongs to the ice-binding protein family. http://togogenome.org/gene/326424:FRAAL_RS04765 ^@ http://purl.uniprot.org/uniprot/Q0RRQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/326424:FRAAL_RS21675 ^@ http://purl.uniprot.org/uniprot/Q0RFY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/326424:FRAAL_RS07950 ^@ http://purl.uniprot.org/uniprot/Q0RPN7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/326424:FRAAL_RS17185 ^@ http://purl.uniprot.org/uniprot/Q0RIU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS19305 ^@ http://purl.uniprot.org/uniprot/Q0RHH1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS27810 ^@ http://purl.uniprot.org/uniprot/Q0RC32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS03405 ^@ http://purl.uniprot.org/uniprot/Q0RSK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS11750 ^@ http://purl.uniprot.org/uniprot/Q0RMA8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS13695 ^@ http://purl.uniprot.org/uniprot/Q0RL27 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS16620 ^@ http://purl.uniprot.org/uniprot/Q0RJ70 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS04820 ^@ http://purl.uniprot.org/uniprot/Q0RRP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/326424:FRAAL_RS15585 ^@ http://purl.uniprot.org/uniprot/Q0RJV3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS17635 ^@ http://purl.uniprot.org/uniprot/Q0RIK1 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/326424:FRAAL_RS06735 ^@ http://purl.uniprot.org/uniprot/Q0RQG6 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS22390 ^@ http://purl.uniprot.org/uniprot/Q0RFH0 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/326424:FRAAL_RS22740 ^@ http://purl.uniprot.org/uniprot/Q0RFA0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/326424:FRAAL_RS24985 ^@ http://purl.uniprot.org/uniprot/Q0RDU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/326424:FRAAL_RS14680 ^@ http://purl.uniprot.org/uniprot/Q0RKF0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/326424:FRAAL_RS15900 ^@ http://purl.uniprot.org/uniprot/Q0RJN2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS30035 ^@ http://purl.uniprot.org/uniprot/Q0RAP2 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/326424:FRAAL_RS17890 ^@ http://purl.uniprot.org/uniprot/Q0RIE2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS20930 ^@ http://purl.uniprot.org/uniprot/Q0RGF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS25230 ^@ http://purl.uniprot.org/uniprot/Q0RDP5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/326424:FRAAL_RS12655 ^@ http://purl.uniprot.org/uniprot/Q0RLR1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS12560 ^@ http://purl.uniprot.org/uniprot/Q0RLT1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/326424:FRAAL_RS22680 ^@ http://purl.uniprot.org/uniprot/Q0RFB2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/326424:FRAAL_RS05045 ^@ http://purl.uniprot.org/uniprot/Q0RRJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/326424:FRAAL_RS28500 ^@ http://purl.uniprot.org/uniprot/Q0RBM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/326424:FRAAL_RS04490 ^@ http://purl.uniprot.org/uniprot/Q0RRV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS25020 ^@ http://purl.uniprot.org/uniprot/Q0RDT9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS16600 ^@ http://purl.uniprot.org/uniprot/Q0RJ75 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS24900 ^@ http://purl.uniprot.org/uniprot/Q0RDW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/326424:FRAAL_RS21075 ^@ http://purl.uniprot.org/uniprot/Q0RGB8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04220 ^@ http://purl.uniprot.org/uniprot/Q0RS17 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/326424:FRAAL_RS16255 ^@ http://purl.uniprot.org/uniprot/Q0RJF1 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/326424:FRAAL_RS04550 ^@ http://purl.uniprot.org/uniprot/Q0RRU6 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/326424:FRAAL_RS21235 ^@ http://purl.uniprot.org/uniprot/Q0RG80 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS06080 ^@ http://purl.uniprot.org/uniprot/Q0RQX1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS05960 ^@ http://purl.uniprot.org/uniprot/Q0RR02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/326424:FRAAL_RS12500 ^@ http://purl.uniprot.org/uniprot/Q0RLU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/326424:FRAAL_RS13840 ^@ http://purl.uniprot.org/uniprot/Q0RKZ3 ^@ Cofactor|||Similarity ^@ Belongs to the Fur family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/326424:FRAAL_RS26240 ^@ http://purl.uniprot.org/uniprot/Q0RD26 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS13710 ^@ http://purl.uniprot.org/uniprot/Q0RL24 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS28865 ^@ http://purl.uniprot.org/uniprot/Q0RBE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17395 ^@ http://purl.uniprot.org/uniprot/Q0RIQ4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS03950 ^@ http://purl.uniprot.org/uniprot/Q0RS75 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/326424:FRAAL_RS00905 ^@ http://purl.uniprot.org/uniprot/Q0RU69 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS28400 ^@ http://purl.uniprot.org/uniprot/Q0RBP8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/326424:FRAAL_RS16135 ^@ http://purl.uniprot.org/uniprot/Q0RJH6 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/326424:FRAAL_RS06535 ^@ http://purl.uniprot.org/uniprot/Q0RQL8 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/326424:FRAAL_RS26440 ^@ http://purl.uniprot.org/uniprot/Q0RCY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS07025 ^@ http://purl.uniprot.org/uniprot/Q0RQ96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS05250 ^@ http://purl.uniprot.org/uniprot/Q0RRF4 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/326424:FRAAL_RS09225 ^@ http://purl.uniprot.org/uniprot/Q0RNW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS22165 ^@ http://purl.uniprot.org/uniprot/Q0RFL9 ^@ Cofactor|||Similarity ^@ Belongs to the class-II DAHP synthase family.|||Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions. http://togogenome.org/gene/326424:FRAAL_RS05560 ^@ http://purl.uniprot.org/uniprot/Q0RR89 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/326424:FRAAL_RS20075 ^@ http://purl.uniprot.org/uniprot/Q0RH01 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/326424:FRAAL_RS10210 ^@ http://purl.uniprot.org/uniprot/Q0RNA7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS12635 ^@ http://purl.uniprot.org/uniprot/Q0RLR5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS01345 ^@ http://purl.uniprot.org/uniprot/Q0RTW8 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/326424:FRAAL_RS04480 ^@ http://purl.uniprot.org/uniprot/Q0RRW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/326424:FRAAL_RS15305 ^@ http://purl.uniprot.org/uniprot/Q0RK11 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/326424:FRAAL_RS20985 ^@ http://purl.uniprot.org/uniprot/Q0RGD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS29750 ^@ http://purl.uniprot.org/uniprot/Q0RAV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/326424:FRAAL_RS25615 ^@ http://purl.uniprot.org/uniprot/Q0RDG1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/326424:FRAAL_RS09825 ^@ http://purl.uniprot.org/uniprot/Q0RNI8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/326424:FRAAL_RS21670 ^@ http://purl.uniprot.org/uniprot/Q0RFY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS16965 ^@ http://purl.uniprot.org/uniprot/Q0RIZ4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS21800 ^@ http://purl.uniprot.org/uniprot/Q0RFU9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/326424:FRAAL_RS00305 ^@ http://purl.uniprot.org/uniprot/Q0RUJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS08580 ^@ http://purl.uniprot.org/uniprot/Q0RPA4 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS12300 ^@ http://purl.uniprot.org/uniprot/Q0RLY6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/326424:FRAAL_RS28630 ^@ http://purl.uniprot.org/uniprot/Q0RBK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS05620 ^@ http://purl.uniprot.org/uniprot/Q0RR76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS27175 ^@ http://purl.uniprot.org/uniprot/Q0RCH2 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/326424:FRAAL_RS21940 ^@ http://purl.uniprot.org/uniprot/Q0RFR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25825 ^@ http://purl.uniprot.org/uniprot/Q0RDB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/326424:FRAAL_RS29945 ^@ http://purl.uniprot.org/uniprot/Q0RAR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS13355 ^@ http://purl.uniprot.org/uniprot/Q0RLA7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS24315 ^@ http://purl.uniprot.org/uniprot/Q0RE95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/326424:FRAAL_RS09605 ^@ http://purl.uniprot.org/uniprot/Q0RNP0 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/326424:FRAAL_RS06060 ^@ http://purl.uniprot.org/uniprot/Q0RQX5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS29410 ^@ http://purl.uniprot.org/uniprot/Q0RB29 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/326424:FRAAL_RS14130 ^@ http://purl.uniprot.org/uniprot/Q0RKT0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS09340 ^@ http://purl.uniprot.org/uniprot/Q0RNU7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RuvA family.|||Cytoplasm|||Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.|||Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA. http://togogenome.org/gene/326424:FRAAL_RS13245 ^@ http://purl.uniprot.org/uniprot/Q0RLC9 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/326424:FRAAL_RS19450 ^@ http://purl.uniprot.org/uniprot/Q0RHE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS04825 ^@ http://purl.uniprot.org/uniprot/Q0RRP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/326424:FRAAL_RS29070 ^@ http://purl.uniprot.org/uniprot/Q0RBA3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/326424:FRAAL_RS29045 ^@ http://purl.uniprot.org/uniprot/Q0RBA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS24690 ^@ http://purl.uniprot.org/uniprot/Q0RE11 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/326424:FRAAL_RS19415 ^@ http://purl.uniprot.org/uniprot/Q0RHE7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS25380 ^@ http://purl.uniprot.org/uniprot/Q0RDK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/326424:FRAAL_RS16300 ^@ http://purl.uniprot.org/uniprot/Q0RJE2 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. http://togogenome.org/gene/326424:FRAAL_RS08305 ^@ http://purl.uniprot.org/uniprot/Q0RPG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS09640 ^@ http://purl.uniprot.org/uniprot/Q0RNN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS10890 ^@ http://purl.uniprot.org/uniprot/Q0RMV6 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/326424:FRAAL_RS04775 ^@ http://purl.uniprot.org/uniprot/Q0RRQ4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/326424:FRAAL_RS10460 ^@ http://purl.uniprot.org/uniprot/Q0RN51 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/326424:FRAAL_RS16890 ^@ http://purl.uniprot.org/uniprot/Q0RJ10 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/326424:FRAAL_RS30945 ^@ http://purl.uniprot.org/uniprot/Q0RPT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS26095 ^@ http://purl.uniprot.org/uniprot/Q0RD59 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. http://togogenome.org/gene/326424:FRAAL_RS25290 ^@ http://purl.uniprot.org/uniprot/Q0RDN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS24735 ^@ http://purl.uniprot.org/uniprot/Q0RE02 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/326424:FRAAL_RS15640 ^@ http://purl.uniprot.org/uniprot/Q0RJT8 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS05210 ^@ http://purl.uniprot.org/uniprot/Q0RRG2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS18325 ^@ http://purl.uniprot.org/uniprot/Q0RI37 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/326424:FRAAL_RS08355 ^@ http://purl.uniprot.org/uniprot/Q0RPF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS09965 ^@ http://purl.uniprot.org/uniprot/Q0RNF6 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/326424:FRAAL_RS14615 ^@ http://purl.uniprot.org/uniprot/Q0RKG4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/326424:FRAAL_RS20005 ^@ http://purl.uniprot.org/uniprot/Q0RH18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/326424:FRAAL_RS18670 ^@ http://purl.uniprot.org/uniprot/Q0RHW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/326424:FRAAL_RS22415 ^@ http://purl.uniprot.org/uniprot/Q0RFG3 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/326424:FRAAL_RS22365 ^@ http://purl.uniprot.org/uniprot/Q0RFH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS24925 ^@ http://purl.uniprot.org/uniprot/Q0RDW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17990 ^@ http://purl.uniprot.org/uniprot/Q0RIB8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS18755 ^@ http://purl.uniprot.org/uniprot/Q0RHU1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/326424:FRAAL_RS05170 ^@ http://purl.uniprot.org/uniprot/Q0RRH0 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/326424:FRAAL_RS06745 ^@ http://purl.uniprot.org/uniprot/Q0RQG4 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/326424:FRAAL_RS22705 ^@ http://purl.uniprot.org/uniprot/Q0RFA7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/326424:FRAAL_RS29370 ^@ http://purl.uniprot.org/uniprot/Q0RB37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS00530 ^@ http://purl.uniprot.org/uniprot/Q0RUE9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/326424:FRAAL_RS04830 ^@ http://purl.uniprot.org/uniprot/Q0RRP3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/326424:FRAAL_RS12520 ^@ http://purl.uniprot.org/uniprot/Q0RLT9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/326424:FRAAL_RS09360 ^@ http://purl.uniprot.org/uniprot/Q0RNU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/326424:FRAAL_RS00175 ^@ http://purl.uniprot.org/uniprot/Q0RUM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS28025 ^@ http://purl.uniprot.org/uniprot/Q0RBY5 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/326424:FRAAL_RS12215 ^@ http://purl.uniprot.org/uniprot/Q0RM05 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/326424:FRAAL_RS04625 ^@ http://purl.uniprot.org/uniprot/Q0RRT6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/326424:FRAAL_RS16695 ^@ http://purl.uniprot.org/uniprot/Q0RJ56 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS06645 ^@ http://purl.uniprot.org/uniprot/Q0RQJ3 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS04140 ^@ http://purl.uniprot.org/uniprot/Q0RS35 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/326424:FRAAL_RS06940 ^@ http://purl.uniprot.org/uniprot/Q0RQB5 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/326424:FRAAL_RS04900 ^@ http://purl.uniprot.org/uniprot/Q0RRM8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS01630 ^@ http://purl.uniprot.org/uniprot/Q0RTQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS15875 ^@ http://purl.uniprot.org/uniprot/Q0RJN7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/326424:FRAAL_RS28120 ^@ http://purl.uniprot.org/uniprot/Q0RBW3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS24600 ^@ http://purl.uniprot.org/uniprot/Q0RE29 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/326424:FRAAL_RS07770 ^@ http://purl.uniprot.org/uniprot/Q0RPS6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/326424:FRAAL_RS17735 ^@ http://purl.uniprot.org/uniprot/Q0RIH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS30180 ^@ http://purl.uniprot.org/uniprot/Q0RSL7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS30020 ^@ http://purl.uniprot.org/uniprot/Q0RAP5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/326424:FRAAL_RS26420 ^@ http://purl.uniprot.org/uniprot/Q0RCZ1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/326424:FRAAL_RS13425 ^@ http://purl.uniprot.org/uniprot/Q0RL87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21895 ^@ http://purl.uniprot.org/uniprot/Q0RFS9 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/326424:FRAAL_RS06200 ^@ http://purl.uniprot.org/uniprot/Q0RQU2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS28350 ^@ http://purl.uniprot.org/uniprot/Q0RBR0 ^@ Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family. http://togogenome.org/gene/326424:FRAAL_RS19810 ^@ http://purl.uniprot.org/uniprot/Q0RH61 ^@ Similarity ^@ Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family. http://togogenome.org/gene/326424:FRAAL_RS29485 ^@ http://purl.uniprot.org/uniprot/Q0RB13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS10810 ^@ http://purl.uniprot.org/uniprot/Q0RMX2 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/326424:FRAAL_RS04860 ^@ http://purl.uniprot.org/uniprot/Q0RRN7 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/326424:FRAAL_RS16070 ^@ http://purl.uniprot.org/uniprot/Q0RJJ1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS09430 ^@ http://purl.uniprot.org/uniprot/Q0RNS7 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/326424:FRAAL_RS26775 ^@ http://purl.uniprot.org/uniprot/Q0RCR2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/326424:FRAAL_RS25200 ^@ http://purl.uniprot.org/uniprot/Q0RDQ1 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/326424:FRAAL_RS28035 ^@ http://purl.uniprot.org/uniprot/Q0RBY3 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/326424:FRAAL_RS18550 ^@ http://purl.uniprot.org/uniprot/Q0RHY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS28345 ^@ http://purl.uniprot.org/uniprot/Q0RBR1 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/326424:FRAAL_RS22785 ^@ http://purl.uniprot.org/uniprot/Q0RF91 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS12495 ^@ http://purl.uniprot.org/uniprot/Q0RLU4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS08710 ^@ http://purl.uniprot.org/uniprot/Q0RP76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS11050 ^@ http://purl.uniprot.org/uniprot/Q0RMS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS26085 ^@ http://purl.uniprot.org/uniprot/Q0RD61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS17580 ^@ http://purl.uniprot.org/uniprot/Q0RIL4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/326424:FRAAL_RS11430 ^@ http://purl.uniprot.org/uniprot/Q0RMI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS22915 ^@ http://purl.uniprot.org/uniprot/Q0RF65 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21805 ^@ http://purl.uniprot.org/uniprot/Q0RFU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS05070 ^@ http://purl.uniprot.org/uniprot/Q0RRJ4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/326424:FRAAL_RS04305 ^@ http://purl.uniprot.org/uniprot/Q0RRZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25205 ^@ http://purl.uniprot.org/uniprot/Q0RDQ0 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/326424:FRAAL_RS20875 ^@ http://purl.uniprot.org/uniprot/Q0RGG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS13345 ^@ http://purl.uniprot.org/uniprot/Q0RLA9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS16360 ^@ http://purl.uniprot.org/uniprot/Q0RJC9 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/326424:FRAAL_RS00300 ^@ http://purl.uniprot.org/uniprot/Q0RUJ5 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/326424:FRAAL_RS06505 ^@ http://purl.uniprot.org/uniprot/Q0RQM5 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/326424:FRAAL_RS06120 ^@ http://purl.uniprot.org/uniprot/Q0RQW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS22905 ^@ http://purl.uniprot.org/uniprot/Q0RF67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/326424:FRAAL_RS09435 ^@ http://purl.uniprot.org/uniprot/Q0RNS6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/326424:FRAAL_RS13365 ^@ http://purl.uniprot.org/uniprot/Q0RLA5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS28210 ^@ http://purl.uniprot.org/uniprot/Q0RBU1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/326424:FRAAL_RS04270 ^@ http://purl.uniprot.org/uniprot/Q0RS04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/326424:FRAAL_RS29805 ^@ http://purl.uniprot.org/uniprot/Q0RAU1 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/326424:FRAAL_RS08975 ^@ http://purl.uniprot.org/uniprot/Q0RP21 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/326424:FRAAL_RS17290 ^@ http://purl.uniprot.org/uniprot/Q0RIS7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/326424:FRAAL_RS29050 ^@ http://purl.uniprot.org/uniprot/Q0RBA8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/326424:FRAAL_RS01770 ^@ http://purl.uniprot.org/uniprot/Q0RTM7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/326424:FRAAL_RS12480 ^@ http://purl.uniprot.org/uniprot/Q0RLU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25595 ^@ http://purl.uniprot.org/uniprot/Q0RDG6 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/326424:FRAAL_RS24385 ^@ http://purl.uniprot.org/uniprot/Q0RE77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS09980 ^@ http://purl.uniprot.org/uniprot/Q0RNF3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/326424:FRAAL_RS24685 ^@ http://purl.uniprot.org/uniprot/Q0RE12 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21810 ^@ http://purl.uniprot.org/uniprot/Q0RFU7 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS21655 ^@ http://purl.uniprot.org/uniprot/Q0RFY5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS02400 ^@ http://purl.uniprot.org/uniprot/Q0RT74 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/326424:FRAAL_RS12410 ^@ http://purl.uniprot.org/uniprot/Q0RLW2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS20435 ^@ http://purl.uniprot.org/uniprot/Q0RGR0 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/326424:FRAAL_RS07350 ^@ http://purl.uniprot.org/uniprot/Q0RQ26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS23485 ^@ http://purl.uniprot.org/uniprot/Q0RET7 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS22695 ^@ http://purl.uniprot.org/uniprot/Q0RFA9 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/326424:FRAAL_RS05625 ^@ http://purl.uniprot.org/uniprot/Q0RR74 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS04945 ^@ http://purl.uniprot.org/uniprot/Q0RRL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/326424:FRAAL_RS05570 ^@ http://purl.uniprot.org/uniprot/Q0RR87 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/326424:FRAAL_RS24950 ^@ http://purl.uniprot.org/uniprot/Q0RDV4 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/326424:FRAAL_RS05065 ^@ http://purl.uniprot.org/uniprot/Q0RRJ5 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS06795 ^@ http://purl.uniprot.org/uniprot/Q0RQF3 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS24875 ^@ http://purl.uniprot.org/uniprot/Q0RDX2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS28480 ^@ http://purl.uniprot.org/uniprot/Q0RBN1 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/326424:FRAAL_RS02685 ^@ http://purl.uniprot.org/uniprot/Q0RT10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS22490 ^@ http://purl.uniprot.org/uniprot/Q0RFE8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS02640 ^@ http://purl.uniprot.org/uniprot/Q0RT19 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/326424:FRAAL_RS16945 ^@ http://purl.uniprot.org/uniprot/Q0RIZ9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS11150 ^@ http://purl.uniprot.org/uniprot/Q0RMQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS21700 ^@ http://purl.uniprot.org/uniprot/Q0RFX6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/326424:FRAAL_RS23595 ^@ http://purl.uniprot.org/uniprot/Q0RER1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25845 ^@ http://purl.uniprot.org/uniprot/Q0RDB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains. http://togogenome.org/gene/326424:FRAAL_RS04805 ^@ http://purl.uniprot.org/uniprot/Q0RRP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/326424:FRAAL_RS01840 ^@ http://purl.uniprot.org/uniprot/Q0RTL3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/326424:FRAAL_RS25925 ^@ http://purl.uniprot.org/uniprot/Q0RD93 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS00620 ^@ http://purl.uniprot.org/uniprot/Q0RUC9 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/326424:FRAAL_RS04695 ^@ http://purl.uniprot.org/uniprot/Q0RRS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS25310 ^@ http://purl.uniprot.org/uniprot/Q0RDM5 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/326424:FRAAL_RS08290 ^@ http://purl.uniprot.org/uniprot/Q0RPG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/326424:FRAAL_RS13605 ^@ http://purl.uniprot.org/uniprot/Q0RL47 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS05265 ^@ http://purl.uniprot.org/uniprot/Q0RRF1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/326424:FRAAL_RS22795 ^@ http://purl.uniprot.org/uniprot/Q0RF89 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/326424:FRAAL_RS01305 ^@ http://purl.uniprot.org/uniprot/Q0RTX6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS22375 ^@ http://purl.uniprot.org/uniprot/Q0RFH3 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/326424:FRAAL_RS25920 ^@ http://purl.uniprot.org/uniprot/Q0RD94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/326424:FRAAL_RS06300 ^@ http://purl.uniprot.org/uniprot/Q0RQR8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/326424:FRAAL_RS18340 ^@ http://purl.uniprot.org/uniprot/Q0RI34 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS08735 ^@ http://purl.uniprot.org/uniprot/Q0RP71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS09210 ^@ http://purl.uniprot.org/uniprot/Q0RNX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS04310 ^@ http://purl.uniprot.org/uniprot/Q0RRZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS13065 ^@ http://purl.uniprot.org/uniprot/Q0RLG9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS13010 ^@ http://purl.uniprot.org/uniprot/Q0RLI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS21130 ^@ http://purl.uniprot.org/uniprot/Q0RGA6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/326424:FRAAL_RS25060 ^@ http://purl.uniprot.org/uniprot/Q0RDT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/326424:FRAAL_RS33975 ^@ http://purl.uniprot.org/uniprot/Q0RLI8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/326424:FRAAL_RS09630 ^@ http://purl.uniprot.org/uniprot/Q0RNN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/326424:FRAAL_RS00565 ^@ http://purl.uniprot.org/uniprot/Q0RUE1 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/326424:FRAAL_RS14620 ^@ http://purl.uniprot.org/uniprot/Q0RKG3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/326424:FRAAL_RS25045 ^@ http://purl.uniprot.org/uniprot/Q0RDT4 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/326424:FRAAL_RS05205 ^@ http://purl.uniprot.org/uniprot/Q0RRG3 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS22595 ^@ http://purl.uniprot.org/uniprot/Q0RFC5 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/326424:FRAAL_RS10020 ^@ http://purl.uniprot.org/uniprot/Q0RNE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS00510 ^@ http://purl.uniprot.org/uniprot/Q0RUF3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS08135 ^@ http://purl.uniprot.org/uniprot/Q0RPJ8 ^@ Cofactor|||Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family.|||Probably binds two magnesium or manganese ions per subunit. http://togogenome.org/gene/326424:FRAAL_RS03860 ^@ http://purl.uniprot.org/uniprot/Q0RS94 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/326424:FRAAL_RS22120 ^@ http://purl.uniprot.org/uniprot/Q0RFM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25805 ^@ http://purl.uniprot.org/uniprot/Q0RDB8 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/326424:FRAAL_RS27915 ^@ http://purl.uniprot.org/uniprot/Q0RC10 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/326424:FRAAL_RS04670 ^@ http://purl.uniprot.org/uniprot/Q0RRS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/326424:FRAAL_RS22945 ^@ http://purl.uniprot.org/uniprot/Q0RF57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/326424:FRAAL_RS27445 ^@ http://purl.uniprot.org/uniprot/Q0RCB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS21310 ^@ http://purl.uniprot.org/uniprot/Q0RG64 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS28515 ^@ http://purl.uniprot.org/uniprot/Q0RBM4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS19710 ^@ http://purl.uniprot.org/uniprot/Q0RH82 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/326424:FRAAL_RS20915 ^@ http://purl.uniprot.org/uniprot/Q0RGF3 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/326424:FRAAL_RS28660 ^@ http://purl.uniprot.org/uniprot/Q0RBJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS27275 ^@ http://purl.uniprot.org/uniprot/Q0RCF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS04715 ^@ http://purl.uniprot.org/uniprot/Q0RRR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). http://togogenome.org/gene/326424:FRAAL_RS08275 ^@ http://purl.uniprot.org/uniprot/Q0RPH1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/326424:FRAAL_RS04810 ^@ http://purl.uniprot.org/uniprot/Q0RRP7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/326424:FRAAL_RS20430 ^@ http://purl.uniprot.org/uniprot/Q0RGR1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS08450 ^@ http://purl.uniprot.org/uniprot/Q0RPD4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS24830 ^@ http://purl.uniprot.org/uniprot/Q0RDY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/326424:FRAAL_RS21640 ^@ http://purl.uniprot.org/uniprot/Q0RFY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS08705 ^@ http://purl.uniprot.org/uniprot/Q0RP77 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/326424:FRAAL_RS15110 ^@ http://purl.uniprot.org/uniprot/Q0RK52 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS25065 ^@ http://purl.uniprot.org/uniprot/Q0RDT0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/326424:FRAAL_RS09900 ^@ http://purl.uniprot.org/uniprot/Q0RNH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/326424:FRAAL_RS06895 ^@ http://purl.uniprot.org/uniprot/Q0RQC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS15290 ^@ http://purl.uniprot.org/uniprot/Q0RK14 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS16095 ^@ http://purl.uniprot.org/uniprot/Q0RJI6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/326424:FRAAL_RS23180 ^@ http://purl.uniprot.org/uniprot/Q0RF02 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/326424:FRAAL_RS03855 ^@ http://purl.uniprot.org/uniprot/Q0RS95 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/326424:FRAAL_RS22325 ^@ http://purl.uniprot.org/uniprot/Q0RFI3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS14220 ^@ http://purl.uniprot.org/uniprot/Q0RKR0 ^@ Function|||Similarity ^@ Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/326424:FRAAL_RS05020 ^@ http://purl.uniprot.org/uniprot/Q0RRK4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/326424:FRAAL_RS29260 ^@ http://purl.uniprot.org/uniprot/Q0RB64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/326424:FRAAL_RS17080 ^@ http://purl.uniprot.org/uniprot/Q0RIX0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/326424:FRAAL_RS17275 ^@ http://purl.uniprot.org/uniprot/Q0RIT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS12905 ^@ http://purl.uniprot.org/uniprot/Q0RLK2 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/326424:FRAAL_RS20070 ^@ http://purl.uniprot.org/uniprot/Q0RH02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/326424:FRAAL_RS24815 ^@ http://purl.uniprot.org/uniprot/Q0RDY5 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/326424:FRAAL_RS28445 ^@ http://purl.uniprot.org/uniprot/Q0RBN8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/326424:FRAAL_RS03065 ^@ http://purl.uniprot.org/uniprot/Q0RSS6 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/326424:FRAAL_RS29925 ^@ http://purl.uniprot.org/uniprot/Q0RAR5 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS14110 ^@ http://purl.uniprot.org/uniprot/Q0RKT5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS08695 ^@ http://purl.uniprot.org/uniprot/Q0RP79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/326424:FRAAL_RS09320 ^@ http://purl.uniprot.org/uniprot/Q0RNV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/326424:FRAAL_RS08840 ^@ http://purl.uniprot.org/uniprot/Q0RP48 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/326424:FRAAL_RS18870 ^@ http://purl.uniprot.org/uniprot/Q0RHR3 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/326424:FRAAL_RS11790 ^@ http://purl.uniprot.org/uniprot/Q0RMA0 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/326424:FRAAL_RS21245 ^@ http://purl.uniprot.org/uniprot/Q0RG78 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS04705 ^@ http://purl.uniprot.org/uniprot/Q0RRR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/326424:FRAAL_RS04545 ^@ http://purl.uniprot.org/uniprot/Q0RRU7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS19345 ^@ http://purl.uniprot.org/uniprot/Q0RHG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS07855 ^@ http://purl.uniprot.org/uniprot/Q0RPQ7 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/326424:FRAAL_RS20495 ^@ http://purl.uniprot.org/uniprot/Q0RGP1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/326424:FRAAL_RS09355 ^@ http://purl.uniprot.org/uniprot/Q0RNU3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/326424:FRAAL_RS00940 ^@ http://purl.uniprot.org/uniprot/Q0RU61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS05355 ^@ http://purl.uniprot.org/uniprot/Q0RRD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS21685 ^@ http://purl.uniprot.org/uniprot/Q0RFX9 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/326424:FRAAL_RS23500 ^@ http://purl.uniprot.org/uniprot/Q0RET4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS24850 ^@ http://purl.uniprot.org/uniprot/Q0RDX7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS25835 ^@ http://purl.uniprot.org/uniprot/Q0RDB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/326424:FRAAL_RS00460 ^@ http://purl.uniprot.org/uniprot/Q0RUG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/326424:FRAAL_RS06930 ^@ http://purl.uniprot.org/uniprot/Q0RQB7 ^@ Function ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. http://togogenome.org/gene/326424:FRAAL_RS02790 ^@ http://purl.uniprot.org/uniprot/Q0RSZ2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/326424:FRAAL_RS29245 ^@ http://purl.uniprot.org/uniprot/Q0RB67 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/326424:FRAAL_RS04500 ^@ http://purl.uniprot.org/uniprot/Q0RRV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS17920 ^@ http://purl.uniprot.org/uniprot/Q0RID3 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/326424:FRAAL_RS18690 ^@ http://purl.uniprot.org/uniprot/Q0RHV6 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/326424:FRAAL_RS22450 ^@ http://purl.uniprot.org/uniprot/Q0RFF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/326424:FRAAL_RS27905 ^@ http://purl.uniprot.org/uniprot/Q0RC12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/326424:FRAAL_RS25085 ^@ http://purl.uniprot.org/uniprot/Q0RDS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/326424:FRAAL_RS21325 ^@ http://purl.uniprot.org/uniprot/Q0RG59 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/326424:FRAAL_RS04650 ^@ http://purl.uniprot.org/uniprot/Q0RRS9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/326424:FRAAL_RS12185 ^@ http://purl.uniprot.org/uniprot/Q0RM11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/326424:FRAAL_RS18945 ^@ http://purl.uniprot.org/uniprot/Q70Z02 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/326424:FRAAL_RS04430 ^@ http://purl.uniprot.org/uniprot/Q0RRX2 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/326424:FRAAL_RS00710 ^@ http://purl.uniprot.org/uniprot/Q0RUA9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS30115 ^@ http://purl.uniprot.org/uniprot/Q0RU43 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/326424:FRAAL_RS04865 ^@ http://purl.uniprot.org/uniprot/Q0RRN6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/326424:FRAAL_RS25500 ^@ http://purl.uniprot.org/uniprot/Q0RDI4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/326424:FRAAL_RS13970 ^@ http://purl.uniprot.org/uniprot/Q0RKW4 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/326424:FRAAL_RS24375 ^@ http://purl.uniprot.org/uniprot/Q0RE79 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/326424:FRAAL_RS06145 ^@ http://purl.uniprot.org/uniprot/Q0RQV3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/326424:FRAAL_RS17965 ^@ http://purl.uniprot.org/uniprot/Q0RIC4 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS18795 ^@ http://purl.uniprot.org/uniprot/Q0RHT0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/326424:FRAAL_RS00240 ^@ http://purl.uniprot.org/uniprot/Q0RUL1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/326424:FRAAL_RS04250 ^@ http://purl.uniprot.org/uniprot/Q0RS10 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/326424:FRAAL_RS00065 ^@ http://purl.uniprot.org/uniprot/Q0RUP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/326424:FRAAL_RS02195 ^@ http://purl.uniprot.org/uniprot/Q0RTC1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/326424:FRAAL_RS08720 ^@ http://purl.uniprot.org/uniprot/Q0RP74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/326424:FRAAL_RS05810 ^@ http://purl.uniprot.org/uniprot/Q0RR37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS08665 ^@ http://purl.uniprot.org/uniprot/Q0RP86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS25895 ^@ http://purl.uniprot.org/uniprot/Q0RD99 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/326424:FRAAL_RS19895 ^@ http://purl.uniprot.org/uniprot/Q0RH42 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/326424:FRAAL_RS29580 ^@ http://purl.uniprot.org/uniprot/Q0RAZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/326424:FRAAL_RS19065 ^@ http://purl.uniprot.org/uniprot/Q0RHM2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/326424:FRAAL_RS04485 ^@ http://purl.uniprot.org/uniprot/Q0RRW0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS27195 ^@ http://purl.uniprot.org/uniprot/Q0RCG8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/326424:FRAAL_RS28365 ^@ http://purl.uniprot.org/uniprot/Q0RBQ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS02255 ^@ http://purl.uniprot.org/uniprot/Q0RTA5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/326424:FRAAL_RS27550 ^@ http://purl.uniprot.org/uniprot/Q0RC92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/326424:FRAAL_RS12640 ^@ http://purl.uniprot.org/uniprot/Q0RLR4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/326424:FRAAL_RS25180 ^@ http://purl.uniprot.org/uniprot/Q0RDQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/326424:FRAAL_RS04460 ^@ http://purl.uniprot.org/uniprot/Q0RRW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/326424:FRAAL_RS18405 ^@ http://purl.uniprot.org/uniprot/Q0RI20 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/326424:FRAAL_RS28040 ^@ http://purl.uniprot.org/uniprot/Q0RBY2 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/326424:FRAAL_RS14705 ^@ http://purl.uniprot.org/uniprot/Q0RKE4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/326424:FRAAL_RS22585 ^@ http://purl.uniprot.org/uniprot/Q0RFC7 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/326424:FRAAL_RS19995 ^@ http://purl.uniprot.org/uniprot/Q0RH20 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.